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Tytuł:
The Role of Decorin in Autoimmune and Inflammatory Diseases.
Autorzy:
Dong Y; Department of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhong J; Department of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Dong L; Department of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Źródło:
Journal of immunology research [J Immunol Res] 2022 Aug 17; Vol. 2022, pp. 1283383. Date of Electronic Publication: 2022 Aug 17 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autoimmune Diseases*
Extracellular Matrix Proteins*
Inflammation*
Proteoglycans*
Decorin ; Extracellular Matrix ; Humans ; Neovascularization, Pathologic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue.
Autorzy:
Meen AJ; Department of Medical Biology, UIT The Arctic University of Norway, 9019 Tromsø, Norway.
Doncheva AI; Department of Nutrition, University of Oslo, 0316 Oslo, Norway.
Böttcher Y; EpiGen, Medical Division, Akershus University Hospital, 1474 Nordbyhagen, Norway.; Department of Endocrinology, Division of Medicine, Akershus University Hospital, 1478 Lørenskog, Norway.
Dankel SN; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway.; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5020 Bergen, Norway.
Hoffmann A; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, 04103 Leipzig, Germany.
Blüher M; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, 04103 Leipzig, Germany.; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, 04103 Leipzig, Germany.
Fernø J; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway.; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5020 Bergen, Norway.
Mellgren G; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway.; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, 5020 Bergen, Norway.
Ghosh A; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, 04103 Leipzig, Germany.
Sun W; Institute of Food, Nutrition and Health, ETH Zurich, 8092 Schwerzenbach, Switzerland.
Dong H; Institute of Food, Nutrition and Health, ETH Zurich, 8092 Schwerzenbach, Switzerland.
Noé F; Institute of Food, Nutrition and Health, ETH Zurich, 8092 Schwerzenbach, Switzerland.
Wolfrum C; Institute of Food, Nutrition and Health, ETH Zurich, 8092 Schwerzenbach, Switzerland.
Pejler G; Department of Medical Biochemistry and Microbiology, Uppsala University, 75123 Uppsala, Sweden.
Dalen KT; Department of Nutrition, University of Oslo, 0316 Oslo, Norway.
Kolset SO; Department of Nutrition, University of Oslo, 0316 Oslo, Norway.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 07; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 07.
Typ publikacji:
Journal Article
MeSH Terms:
Proteoglycans*/genetics
Proteoglycans*/metabolism
Adipose Tissue*/metabolism
Female ; Humans ; Male ; Animals ; Mice ; Obesity/genetics ; Obesity/metabolism ; Subcutaneous Fat/metabolism ; Adiposity ; Extracellular Matrix Proteins/metabolism ; Diet, High-Fat/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification.
Autorzy:
Skenteris NT; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden.; Division of Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.; Department of Biochemistry and CARIM, School for Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands.
Seime T; Division of Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Witasp A; Division of Renal Medicine, Department of Clinical Sciences, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.
Karlöf E; Division of Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Wasilewski GB; Department of Biochemistry and CARIM, School for Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands.; Nattopharma ASA, Oslo, Norway.
Heuschkel MA; Department of Biochemistry and CARIM, School for Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands.; Department of Internal Medicine I-Cardiology, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Jaminon AMG; Department of Biochemistry and CARIM, School for Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands.
Oduor L; Department of Clinical Sciences Malmö and Cardiology, Skåne University Hospital, Lund University, Lund, Sweden.
Dzhanaev R; Department of Biochemistry and CARIM, School for Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands.; Biointerface Group, Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Kronqvist M; Division of Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Lengquist M; Division of Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Peeters FECM; Department of Cardiology and CARIM, School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht, Netherlands.
Söderberg M; Cardiovascular, Renal and Metabolism Safety, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
Hultgren R; Division of Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Roy J; Division of Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Maegdefessel L; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden.; Klinikum rechts der Isar, Department for Vascular and Endovascular Surgery, Technical University Munich, Munich, Germany.
Arnardottir H; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden.
Bengtsson E; Department of Clinical Sciences Malmö and Cardiology, Skåne University Hospital, Lund University, Lund, Sweden.
Goncalves I; Department of Clinical Sciences Malmö and Cardiology, Skåne University Hospital, Lund University, Lund, Sweden.
Quertermous T; Department of Cardiovascular Medicine, University of Stanford, Stanford, California, USA.
Goettsch C; Department of Internal Medicine I-Cardiology, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Stenvinkel P; Division of Renal Medicine, Department of Clinical Sciences, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.
Schurgers LJ; Department of Biochemistry and CARIM, School for Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands.; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen, Germany.
Matic L; Division of Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Feb; Vol. 12 (2), pp. e682.
Typ publikacji:
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Extracellular Matrix Proteins/*pharmacology
Muscle, Smooth/*drug effects
Osteogenesis/*genetics
Proteoglycans/*pharmacology
Vascular Calcification/*etiology
Analysis of Variance ; Cohort Studies ; Cross-Sectional Studies ; Extracellular Matrix Proteins/metabolism ; Humans ; Linear Models ; Muscle, Smooth/physiology ; Netherlands ; Osteogenesis/physiology ; Prospective Studies ; Proteoglycans/metabolism ; Statistics, Nonparametric ; Sweden ; Vascular Calcification/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of proteoglycan form of DMP1 in cranial repair.
Autorzy:
Liu Y; Central Laboratory, The First Affiliated Hospital of Qiqihaer Medical University, Qiqihaer, Heilongjiang, China.
Niu P; Department of Implantology, School & Hospital of Stomatology, Tongji University, Shanghai, China.
Zhou M; Department of Endodontics, Shanghai Stomatological Hospital & Oral Biomedical Engineering LaboratoryShanghai Stomatological HospitalFudan University, Shanghai, China.
Xue H; Department of Stomatology, The First Affiliated Hospital of Qiqihaer Medical University, 26 Xiangyang Road, Fulaerji District, Heilongjiang, 161041, Qiqihaer, China. .
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Źródło:
BMC molecular and cell biology [BMC Mol Cell Biol] 2022 Sep 30; Vol. 23 (1), pp. 43. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Osteogenesis*
Proteoglycans*/genetics
Animals ; Disease Models, Animal ; Extracellular Matrix Proteins ; Mice ; Osteoblasts ; RNA ; X-Ray Microtomography
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Significant association of serum autoantibodies to TYMS, HAPLN1 and IGFBP5 with early stage canine malignant mammary tumours.
Autorzy:
Chang SC; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Yuan SH; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Li CY; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Chang HM; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Wang HC; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Pan YA; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Hsueh PC; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Wu CC; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Yang Y; Division of Hematology-Oncology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Liu HP; Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
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Źródło:
Veterinary and comparative oncology [Vet Comp Oncol] 2021 Mar; Vol. 19 (1), pp. 172-182. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
Dog Diseases/*immunology
Extracellular Matrix Proteins/*metabolism
Insulin-Like Growth Factor Binding Protein 5/*metabolism
Mammary Neoplasms, Animal/*immunology
Proteoglycans/*metabolism
Thymidylate Synthase/*metabolism
Animals ; Autoantibodies/blood ; Biomarkers, Tumor ; Carcinoma/metabolism ; Carcinoma/veterinary ; Dog Diseases/blood ; Dogs ; Extracellular Matrix Proteins/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Insulin-Like Growth Factor Binding Protein 5/genetics ; Mammary Neoplasms, Animal/metabolism ; Neoplasm Staging/veterinary ; Proteoglycans/genetics ; Thymidylate Synthase/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Into the Tissues: Extracellular Matrix and Its Artificial Substitutes: Cell Signalling Mechanisms.
Autorzy:
Bandzerewicz A; Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3 Street, 00-664 Warsaw, Poland.
Gadomska-Gajadhur A; Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3 Street, 00-664 Warsaw, Poland.
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Źródło:
Cells [Cells] 2022 Mar 07; Vol. 11 (5). Date of Electronic Publication: 2022 Mar 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Extracellular Matrix*/metabolism
Proteoglycans*/metabolism
Collagen/metabolism ; Extracellular Matrix Proteins/metabolism ; Glycoproteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI.
Autorzy:
Hansen U; Department of Physiological Chemistry & Pathobiochemistry, University Hospital of Münster, Münster, Germany.; Institute of Musculoskeletal Medicine, University Hospital Münster, Münster, Germany.
Holmes DF; Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Bruckner P; Department of Physiological Chemistry & Pathobiochemistry, University Hospital of Münster, Münster, Germany.
Bishop PN; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
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Źródło:
PloS one [PLoS One] 2020 Aug 07; Vol. 15 (8), pp. e0234672. Date of Electronic Publication: 2020 Aug 07 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Collagen/*metabolism
Extracellular Matrix Proteins/*metabolism
Proteoglycans/*metabolism
Animals ; Binding Sites ; Cattle ; Collagen/chemistry ; Collagen/ultrastructure ; Extracellular Matrix Proteins/chemistry ; Extracellular Matrix Proteins/deficiency ; In Vitro Techniques ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microscopy, Electron, Transmission ; Microscopy, Immunoelectron ; Protein Binding ; Proteoglycans/chemistry ; Proteoglycans/deficiency ; Vitreous Body/chemistry ; Vitreous Body/metabolism ; Vitreous Body/ultrastructure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An interplay of microglia and matrix metalloproteinase MMP9 under hypoxic stress regulates the opticin expression in retina.
Autorzy:
Patnaik S; Prof. Brien Holden Eye Research Centre, LV Prasad Eye Institute, Hyderabad, India.; Department of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Rai M; Prof. Brien Holden Eye Research Centre, LV Prasad Eye Institute, Hyderabad, India.
Jalali S; Smt. Kannuri Santhamma Centre for Vitreo Retinal Diseases, Hyderabad, India.
Agarwal K; Smt. Kannuri Santhamma Centre for Vitreo Retinal Diseases, Hyderabad, India.
Badakere A; Jasti V Ramanamma Children's Eye Care Centre, LV Prasad Eye Institute, Hyderabad, India.
Puppala L; Prof. Brien Holden Eye Research Centre, LV Prasad Eye Institute, Hyderabad, India.
Vishwakarma S; Prof. Brien Holden Eye Research Centre, LV Prasad Eye Institute, Hyderabad, India.
Balakrishnan D; Smt. Kannuri Santhamma Centre for Vitreo Retinal Diseases, Hyderabad, India.
Rani PK; Smt. Kannuri Santhamma Centre for Vitreo Retinal Diseases, Hyderabad, India.
Kekunnaya R; Jasti V Ramanamma Children's Eye Care Centre, LV Prasad Eye Institute, Hyderabad, India.
Chhablani PP; Jasti V Ramanamma Children's Eye Care Centre, LV Prasad Eye Institute, Hyderabad, India.; University of Pittsburgh Medical Center, Pittsburgh, USA.
Chakrabarti S; Prof. Brien Holden Eye Research Centre, LV Prasad Eye Institute, Hyderabad, India.
Kaur I; Prof. Brien Holden Eye Research Centre, LV Prasad Eye Institute, Hyderabad, India. .
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Źródło:
Scientific reports [Sci Rep] 2021 Apr 02; Vol. 11 (1), pp. 7444. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Stress, Physiological*/drug effects
Extracellular Matrix Proteins/*metabolism
Hypoxia/*metabolism
Matrix Metalloproteinase 9/*metabolism
Microglia/*metabolism
Proteoglycans/*metabolism
Retina/*metabolism
Case-Control Studies ; Computer Simulation ; Doxycycline/metabolism ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Gene Expression Regulation/drug effects ; Humans ; Infant ; Infant, Newborn ; Ligands ; Matrix Metalloproteinase Inhibitors/pharmacology ; Microglia/drug effects ; Models, Biological ; Protein Binding/drug effects ; Retina/drug effects ; Retinopathy of Prematurity/genetics ; Retinopathy of Prematurity/metabolism ; Retinopathy of Prematurity/pathology ; Signal Transduction/drug effects ; Tissue Inhibitor of Metalloproteinase-2/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Distinct effects of different matrix proteoglycans on collagen fibrillogenesis and cell-mediated collagen reorganization.
Autorzy:
Chen D; Bioengineering Graduate Group, University of Pennsylvania, Philadelphia, PA, 19104, USA.; National Science Foundation Center for Engineering MechanoBiology, Philadelphia, PA, 19104, USA.; The Materials Research Science & Engineering Center, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Smith LR; Department of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Khandekar G; Department of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Patel P; School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, 19104, USA.
Yu CK; Bioengineering Graduate Group, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Zhang K; Department of Biomedical Engineering, Boston University, Boston, MA, 02215, USA.
Chen CS; National Science Foundation Center for Engineering MechanoBiology, Philadelphia, PA, 19104, USA.; Department of Biomedical Engineering, Boston University, Boston, MA, 02215, USA.
Han L; School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, 19104, USA.
Wells RG; Bioengineering Graduate Group, University of Pennsylvania, Philadelphia, PA, 19104, USA. .; National Science Foundation Center for Engineering MechanoBiology, Philadelphia, PA, 19104, USA. .; The Materials Research Science & Engineering Center, University of Pennsylvania, Philadelphia, PA, 19104, USA. .; Department of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. .; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 04; Vol. 10 (1), pp. 19065. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Collagen/*metabolism
Extracellular Matrix/*metabolism
Extracellular Matrix Proteins/*metabolism
Fibrosis/*metabolism
Proteoglycans/*metabolism
Animals ; Cell Line ; Extracellular Matrix/ultrastructure ; Fibrillar Collagens/metabolism ; Mice ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bull's eye maculopathy caused by a novel IMPG-1 mutation.
Autorzy:
González-Gómez A; a Servicio de Oftalmología , Hospital Universitario Virgen de la Victoria , Málaga , Spain.
Romero-Trevejo JL; a Servicio de Oftalmología , Hospital Universitario Virgen de la Victoria , Málaga , Spain.
García-Ben A; b Servicio de Oftalmología , Hospital Clínico Universitario de Santiago , Santiago de Compostela , Spain.
García-Campos JM; a Servicio de Oftalmología , Hospital Universitario Virgen de la Victoria , Málaga , Spain.
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Źródło:
Ophthalmic genetics [Ophthalmic Genet] 2019 Feb; Vol. 40 (1), pp. 71-73. Date of Electronic Publication: 2018 Dec 27.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Mutation*
Extracellular Matrix Proteins/*genetics
Eye Proteins/*genetics
Macular Degeneration/*pathology
Proteoglycans/*genetics
Adult ; Female ; Humans ; Macular Degeneration/etiology ; Prognosis
SCR Disease Name:
Macular dystrophy, concentric annular
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The small leucine rich proteoglycan fibromodulin is overexpressed in human prostate epithelial cancer cell lines in culture and human prostate cancer tissue.
Autorzy:
Reyes N; School of Medicine, University of Cartagena, Cartagena, Colombia.; Research Group of Genetics and Molecular Biology, Colombia.
Benedetti I; School of Medicine, University of Cartagena, Cartagena, Colombia.
Bettin A; School of Medicine, University of Cartagena, Cartagena, Colombia.; Research Group of Genetics and Molecular Biology, Colombia.
Rebollo J; School of Medicine, University of Cartagena, Cartagena, Colombia.; Research Group of Genetics and Molecular Biology, Colombia.
Geliebter J; New York Medical College, Valhalla, NY, USA.
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Źródło:
Cancer biomarkers : section A of Disease markers [Cancer Biomark] 2016; Vol. 16 (1), pp. 191-202.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression*
Extracellular Matrix Proteins/*genetics
Prostatic Neoplasms/*genetics
Proteoglycans/*genetics
Biopsy ; Cell Line, Tumor ; Extracellular Matrix ; Extracellular Matrix Proteins/metabolism ; Fibromodulin ; Genes, Essential ; Humans ; Immunohistochemistry ; Male ; Prostate/metabolism ; Prostate/pathology ; Prostatic Hyperplasia/genetics ; Prostatic Hyperplasia/metabolism ; Prostatic Neoplasms/metabolism ; Proteoglycans/metabolism ; RNA, Messenger/genetics ; Transcription, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Matricryptins and matrikines: biologically active fragments of the extracellular matrix.
Autorzy:
Ricard-Blum S; Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS, Université Lyon 1, Lyon Cedex 07, France.
Salza R
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Źródło:
Experimental dermatology [Exp Dermatol] 2014 Jul; Vol. 23 (7), pp. 457-63.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Extracellular Matrix Proteins/*physiology
Glycosaminoglycans/*metabolism
Proteoglycans/*metabolism
Animals ; Extracellular Matrix/metabolism ; Extracellular Matrix Proteins/metabolism ; Humans ; Inflammation ; Mice ; Models, Theoretical ; Neoplasms/metabolism ; Neovascularization, Pathologic ; Neurodegenerative Diseases/physiopathology ; Protein Structure, Tertiary ; Proteomics ; Skin Diseases/metabolism ; Systems Biology ; Wound Healing/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comparison of secretome from osteoblasts derived from sclerotic versus non-sclerotic subchondral bone in OA: A pilot study.
Autorzy:
Sanchez C; Bone and Cartilage Research Unit, Arthropôle Liège, University of Liège, Liège, Belgium.
Mazzucchelli G; Laboratory of Mass Spectrometry-MolSys, Department of Chemistry, University of Liege, Liege, Belgium.
Lambert C; Bone and Cartilage Research Unit, Arthropôle Liège, University of Liège, Liège, Belgium.
Comblain F; Bone and Cartilage Research Unit, Arthropôle Liège, University of Liège, Liège, Belgium.
DePauw E; Laboratory of Mass Spectrometry-MolSys, Department of Chemistry, University of Liege, Liege, Belgium.
Henrotin Y; Bone and Cartilage Research Unit, Arthropôle Liège, University of Liège, Liège, Belgium.
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Źródło:
PloS one [PLoS One] 2018 Mar 16; Vol. 13 (3), pp. e0194591. Date of Electronic Publication: 2018 Mar 16 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone and Bones/*metabolism
Extracellular Matrix Proteins/*metabolism
Osteoarthritis, Knee/*pathology
Osteoblasts/*metabolism
Osteosclerosis/*pathology
Proteoglycans/*metabolism
Adult ; Aged ; Aged, 80 and over ; Biomarkers/analysis ; Bone Remodeling/physiology ; Bone and Bones/cytology ; Bone and Bones/pathology ; Calcification, Physiologic ; Cells, Cultured ; Enzyme-Linked Immunosorbent Assay ; Humans ; Male ; Middle Aged ; Osteoarthritis, Knee/diagnosis ; Pilot Projects ; Proteomics ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Link protein N-terminal peptide and fullerol promote matrix production and decrease degradation enzymes in rabbit annulus cells.
Autorzy:
Yeh CH; a Department of Orthopaedic Surgery , University of Virginia , Charlottesville , VA , USA.; b Centre for Infectious Disease and Cancer Research , Kaohsiung Medical University , Kaohsiung , Taiwan.
Chen D; a Department of Orthopaedic Surgery , University of Virginia , Charlottesville , VA , USA.
Aghdasi B; a Department of Orthopaedic Surgery , University of Virginia , Charlottesville , VA , USA.
Xiao L; a Department of Orthopaedic Surgery , University of Virginia , Charlottesville , VA , USA.
Ding M; a Department of Orthopaedic Surgery , University of Virginia , Charlottesville , VA , USA.
Jin L; a Department of Orthopaedic Surgery , University of Virginia , Charlottesville , VA , USA.
Li X; a Department of Orthopaedic Surgery , University of Virginia , Charlottesville , VA , USA.
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Źródło:
Connective tissue research [Connect Tissue Res] 2018 Mar; Vol. 59 (2), pp. 191-200. Date of Electronic Publication: 2017 Jun 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Annulus Fibrosus/*metabolism
Extracellular Matrix/*metabolism
Extracellular Matrix Proteins/*pharmacology
Fullerenes/*pharmacology
Peptides/*pharmacology
Proteoglycans/*pharmacology
Animals ; Annulus Fibrosus/pathology ; Collagenases/biosynthesis ; Cyclooxygenase 2/biosynthesis ; Extracellular Matrix/pathology ; Interleukin-1alpha/biosynthesis ; Interleukin-6/biosynthesis ; Intervertebral Disc Degeneration/drug therapy ; Intervertebral Disc Degeneration/metabolism ; Intervertebral Disc Degeneration/pathology ; Male ; Rabbits
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Link-N: The missing link towards intervertebral disc repair is species-specific.
Autorzy:
Bach FC; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Laagland LT; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Grant MP; Department of Surgery, McGill University, Montreal, Canada.; Orthopedic Research Laboratory, Lady Davis Institute for Medical Research, SMBD-Jewish General Hospital, Montreal, Canada.
Creemers LB; Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands.
Ito K; Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands.; Orthopedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
Meij BP; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Mwale F; Department of Surgery, McGill University, Montreal, Canada.
Tryfonidou MA; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
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Źródło:
PloS one [PLoS One] 2017 Nov 08; Vol. 12 (11), pp. e0187831. Date of Electronic Publication: 2017 Nov 08 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Chondrocytes/*drug effects
Extracellular Matrix/*drug effects
Extracellular Matrix Proteins/*chemistry
Peptides/*pharmacology
Proteoglycans/*chemistry
Regeneration/*drug effects
Amino Acid Sequence ; Animals ; Back Pain/complications ; Back Pain/genetics ; Back Pain/metabolism ; Back Pain/physiopathology ; Cattle ; Cells, Cultured ; Chondrocytes/metabolism ; Chondrocytes/pathology ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Collagen Type II/genetics ; Collagen Type II/metabolism ; DNA/metabolism ; Dogs ; Gene Expression Regulation ; Glycosaminoglycans/metabolism ; Humans ; Intervertebral Disc/drug effects ; Intervertebral Disc/metabolism ; Intervertebral Disc/pathology ; Intervertebral Disc Degeneration/complications ; Intervertebral Disc Degeneration/genetics ; Intervertebral Disc Degeneration/metabolism ; Intervertebral Disc Degeneration/pathology ; Smad1 Protein/genetics ; Smad1 Protein/metabolism ; Smad2 Protein/genetics ; Smad2 Protein/metabolism ; Species Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effect of decorin and dermatan sulfate on the mechanical properties of a neocartilage.
Autorzy:
Lewis JL; Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA. />Krawczak DA
Oegema TR Jr
Westendorf JJ
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Źródło:
Connective tissue research [Connect Tissue Res] 2010 Apr; Vol. 51 (2), pp. 159-70.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cartilage, Articular/*physiology
Chondrocytes/*physiology
Dermatan Sulfate/*metabolism
Extracellular Matrix Proteins/*metabolism
Proteoglycans/*metabolism
Animals ; Biomechanical Phenomena ; Cartilage, Articular/cytology ; Cells, Cultured ; Chondrocytes/cytology ; Collagen/metabolism ; Decorin ; Dermatan Sulfate/deficiency ; Dermatan Sulfate/genetics ; Extracellular Matrix/drug effects ; Extracellular Matrix Proteins/deficiency ; Extracellular Matrix Proteins/genetics ; Genetic Vectors ; Male ; Proteoglycans/genetics ; Rabbits ; Stress, Mechanical ; Tissue Engineering ; Transduction, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stimulation of small proteoglycan synthesis by the hyaluronan synthesis inhibitor 4-methylumbelliferone in human skin fibroblasts.
Autorzy:
Funahashi M; Department of Glycotechnology, Center for Advanced Medical Research, and Departments of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Japan. />Nakamura T
Kakizaki I
Mizunuma H
Endo M
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Źródło:
Connective tissue research [Connect Tissue Res] 2009; Vol. 50 (3), pp. 194-202.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Matrix Proteins/*biosynthesis
Hyaluronic Acid/*antagonists & inhibitors
Hymecromone/*analogs & derivatives
Proteoglycans/*biosynthesis
Skin/*drug effects
Cells, Cultured ; Decorin ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Extracellular Matrix Proteins/chemistry ; Extracellular Matrix Proteins/isolation & purification ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Humans ; Hyaluronic Acid/biosynthesis ; Hyaluronic Acid/isolation & purification ; Hymecromone/pharmacology ; Proteoglycans/chemistry ; Proteoglycans/isolation & purification ; Skin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Decorin is a secreted protein associated with obesity and type 2 diabetes.
Autorzy:
Bolton K; Metabolic Research Unit, School of Exercise and Nutrition Sciences, Deakin University, Waurn Ponds, Victoria, Australia.
Segal D
McMillan J
Jowett J
Heilbronn L
Abberton K
Zimmet P
Chisholm D
Collier G
Walder K
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2008 Jul; Vol. 32 (7), pp. 1113-21. Date of Electronic Publication: 2008 Apr 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Adipose Tissue/*metabolism
Diabetes Mellitus, Type 2/*metabolism
Extracellular Matrix Proteins/*analysis
Obesity/*metabolism
Proteoglycans/*analysis
Abdominal Fat/metabolism ; Adult ; Aged ; Animals ; Decorin ; Diabetes Mellitus, Type 2/blood ; Enzyme-Linked Immunosorbent Assay/methods ; Extracellular Matrix Proteins/blood ; Extracellular Matrix Proteins/genetics ; Female ; Gene Expression ; Gerbillinae ; Glucose Intolerance ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Models, Animal ; Proteoglycans/blood ; Proteoglycans/genetics ; RNA, Messenger/metabolism ; Regression Analysis ; Reverse Transcriptase Polymerase Chain Reaction/methods ; Subcutaneous Fat/metabolism ; Tissue Distribution ; Waist-Hip Ratio
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord.
Autorzy:
Galtrey CM; Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Robinson Way, Cambridge, CB2 2PY, UK.
Kwok JC
Carulli D
Rhodes KE
Fawcett JW
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2008 Mar; Vol. 27 (6), pp. 1373-90.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Extracellular Matrix/*metabolism
Extracellular Matrix Proteins/*metabolism
Hyaluronic Acid/*metabolism
Proteoglycans/*metabolism
Spinal Cord/*chemistry
Spinal Cord/*metabolism
Tenascin/*metabolism
Animals ; Animals, Newborn ; Dendrites/chemistry ; Dendrites/metabolism ; Extracellular Matrix/chemistry ; Extracellular Matrix/genetics ; Extracellular Matrix Proteins/biosynthesis ; Extracellular Matrix Proteins/genetics ; Gene Expression Regulation, Developmental/physiology ; Hyaluronic Acid/biosynthesis ; Hyaluronic Acid/genetics ; Neurons/chemistry ; Neurons/metabolism ; Proteoglycans/biosynthesis ; Proteoglycans/genetics ; Rats ; Rats, Sprague-Dawley ; Spinal Cord/cytology ; Tenascin/biosynthesis ; Tenascin/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Treatment with triamcinolone acetonide prevents decreased retinal levels of decorin in a rat model of oxygen-induced retinopathy.
Autorzy:
Park YJ; Department of Ophthalmology, School of Medicine, Institute of Health Science, Gyeongsang National University, Jinju, Gyeongnam, Korea, Republic of Korea.
Kim YH
Choi WS
Chung IY
Yoo JM
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Źródło:
Current eye research [Curr Eye Res] 2010 Jul; Vol. 35 (7), pp. 657-63.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Models, Animal*
Extracellular Matrix Proteins/*metabolism
Glucocorticoids/*therapeutic use
Hyperoxia/*drug therapy
Proteoglycans/*metabolism
Retina/*metabolism
Retinopathy of Prematurity/*drug therapy
Triamcinolone Acetonide/*therapeutic use
Animals ; Animals, Newborn ; Blotting, Western ; Cell Death ; Decorin ; Extracellular Matrix Proteins/genetics ; Female ; Humans ; Hyperoxia/metabolism ; Hyperoxia/pathology ; Immunohistochemistry ; In Situ Nick-End Labeling ; Infant, Newborn ; Oxygen/toxicity ; Pregnancy ; Proteoglycans/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Retinal Ganglion Cells/drug effects ; Retinal Ganglion Cells/pathology ; Retinopathy of Prematurity/metabolism ; Retinopathy of Prematurity/pathology ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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