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Wyszukujesz frazę ""Extracellular Signal-Regulated MAP Kinases -- metabolism"" wg kryterium: Temat

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Wyświetlanie 1-20 z 45
Podgląd okładki
Tytuł :
Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation
Index Terms :
Colorectal Neoplasms/diagnosis
Electrophoresis, Capillary/methods
Extracellular Signal-Regulated MAP Kinases/metabolism
Human Umbilical Vein Endothelial Cells/metabolism
Humans
Isoelectric Focusing/methods
Nanoparticles/chemistry
Nucleic Acid Amplification Techniques/methods
Phosphorylation
Proteins/analysis
Sensitivity and Specificity
Signal Transduction/drug effects
Vascular Endothelial Growth Factor A/pharmacology
Journal Article
Research Support, Non-U.S. Gov't
Tijdschriftartikel
Article
Źródło :
Scientific Reports vol.7 (2017) date: 2017-05-04 nr.1 [ISSN 2045-2322]
URL :
https://research.tue.nl/en/publications/highly-sensitive-and-specific-protein-detection-via-combined-capillary-isoelectric-focusing-and-proximity-ligation(f2398458-50c5-4d28-bde6-ed9487fd8a92).html">https://research.tue.nl/en/publications/highly-sensitive-and-specific-protein-detection-via-combined-capillary-isoelectric-focusing-and-proximity-ligation(f2398458-50c5-4d28-bde6-ed9487fd8a92).html
https://pure.tue.nl/ws/files/73246581/s41598_017_01516_7.pdf">https://pure.tue.nl/ws/files/73246581/s41598_017_01516_7.pdf
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogenic KRas-mutant cancer cells.
Index Terms :
Cell Line, Tumor
Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors
Extracellular Signal-Regulated MAP Kinases/genetics
Extracellular Signal-Regulated MAP Kinases/metabolism
Gene Expression Regulation, Neoplastic/drug effects
Humans
Intracellular Signaling Peptides and Proteins/genetics
Intracellular Signaling Peptides and Proteins/metabolism
MAP Kinase Signaling System/drug effects
MAP Kinase Signaling System/genetics
Multiprotein Complexes/biosynthesis
Multiprotein Complexes/genetics
Mutation
Neoplasms/drug therapy
Neoplasms/genetics
Neoplasms/metabolism
Phosphatidylinositol 3-Kinases/genetics
Phosphatidylinositol 3-Kinases/metabolism
Protein Kinase Inhibitors/pharmacology
Proto-Oncogene Proteins/genetics
Proto-Oncogene Proteins/metabolism
Proto-Oncogene Proteins B-raf/genetics
Proto-Oncogene Proteins B-raf/metabolism
TOR Serine-Threonine Kinases/biosynthesis
TOR Serine-Threonine Kinases/genetics
Telomerase/genetics
Telomerase/metabolism
Tumor Suppressor Proteins/genetics
Tumor Suppressor Proteins/metabolism
Up-Regulation/drug effects
ras Proteins/genetics
ras Proteins/metabolism
Journal Article
URL :
http://hdl.handle.net/2433/207613">http://hdl.handle.net/2433/207613
10.1038/onc.2015.16
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Fluorescence resonance energy transfer based quantitative analysis of feedforward and feedback loops in epidermal growth factor receptor signaling and the sensitivity to molecular targeting drugs.
Index Terms :
Akt
EGFR
ERK
FRET
simulation
Drug Delivery Systems
Extracellular Signal-Regulated MAP Kinases/metabolism
Feedback, Physiological/physiology
Fluorescence Resonance Energy Transfer
HeLa Cells
Homeostasis/physiology
Humans
MAP Kinase Signaling System/physiology
Monomeric GTP-Binding Proteins/physiology
Neuropeptides/physiology
Phosphatidylinositol 3-Kinases/physiology
Proto-Oncogene Proteins B-raf/physiology
Proto-Oncogene Proteins c-akt/metabolism
Receptor, Epidermal Growth Factor/physiology
Ribosomal Protein S6 Kinases/physiology
Signal Transduction/physiology
Systems Biology
TOR Serine-Threonine Kinases/physiology
Journal Article
URL :
http://hdl.handle.net/2433/199651">http://hdl.handle.net/2433/199651
10.1111/febs.12852
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Heterogeneity in ERK activity as visualized by in vivo FRET imaging of mammary tumor cells developed in MMTV-Neu mice.
Index Terms :
Animals
Antineoplastic Agents/pharmacokinetics
Benzamides/pharmacokinetics
Computer Systems
Diphenylamine/analogs & derivatives
Diphenylamine/pharmacokinetics
Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors
Extracellular Signal-Regulated MAP Kinases/metabolism
Female
Fluorescence Resonance Energy Transfer
Genes, erbB-2
Mammary Neoplasms, Experimental/genetics
Mammary Neoplasms, Experimental/metabolism
Mammary Neoplasms, Experimental/pathology
Mammary Tumor Virus, Mouse/genetics
Mice
Mice, Transgenic
Molecular Imaging/methods
Neoplasm Metastasis
Protein Kinase Inhibitors/pharmacokinetics
Journal Article
URL :
http://hdl.handle.net/2433/198805">http://hdl.handle.net/2433/198805
10.1038/onc.2014.28
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Thioredoxin-interacting protein suppresses bladder carcinogenesis.
Index Terms :
Aged
Animals
Blotting, Western
Butylhydroxybutylnitrosamine/toxicity
Carrier Proteins/genetics
Carrier Proteins/metabolism
Carrier Proteins/physiology
Chemokine CXCL12/genetics
Chemokine CXCL12/metabolism
Disease Models, Animal
Extracellular Signal-Regulated MAP Kinases/genetics
Extracellular Signal-Regulated MAP Kinases/metabolism
Female
Humans
Immunoenzyme Techniques
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Neoplasm Staging
Prognosis
RNA, Messenger/genetics
Receptors, CXCR4/antagonists & inhibitors
Receptors, CXCR4/genetics
Receptors, CXCR4/metabolism
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Survival Rate
Thioredoxins/metabolism
Thioredoxins/physiology
Urinary Bladder Neoplasms/chemically induced
Urinary Bladder Neoplasms/metabolism
Urinary Bladder Neoplasms/pathology
Journal Article
URL :
http://hdl.handle.net/2433/158366">http://hdl.handle.net/2433/158366
10.1093/carcin/bgr137
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.
Index Terms :
Animals
Antigens, CD44/metabolism
Cytokines/genetics/metabolism
Down-Regulation/genetics
Extracellular Signal-Regulated MAP Kinases/metabolism
Forkhead Transcription Factors
Gene Knockdown Techniques
Humans
L-Selectin/metabolism
MAP Kinase Signaling System
Mice
Mice, Knockout
STAT5 Transcription Factor/metabolism
Signal Transduction/genetics
T-Lymphocytes, Regulatory/enzymology/metabolism
Time Factors
Transcriptome/genetics
Urokinase-Type Plasminogen Activator/genetics/metabolism
info:eu-repo/semantics/article
URL :
http://orbilu.uni.lu/handle/10993/910">http://orbilu.uni.lu/handle/10993/910
http://orbilu.uni.lu/bitstream/10993/910/1/Feng_HE_PLAU_Treg_MSB%2C%202012.pdf">http://orbilu.uni.lu/bitstream/10993/910/1/Feng_HE_PLAU_Treg_MSB%2C%202012.pdf
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.
Index Terms :
Animals
Antigens, CD44/metabolism
Cytokines/genetics/metabolism
Down-Regulation/genetics
Extracellular Signal-Regulated MAP Kinases/metabolism
Forkhead Transcription Factors
Gene Knockdown Techniques
Humans
L-Selectin/metabolism
MAP Kinase Signaling System
Mice
Mice, Knockout
STAT5 Transcription Factor/metabolism
Signal Transduction/genetics
T-Lymphocytes, Regulatory/enzymology/metabolism
Time Factors
Transcriptome/genetics
Urokinase-Type Plasminogen Activator/genetics/metabolism
info:eu-repo/semantics/article
URL :
http://orbilu.uni.lu/handle/10993/910">http://orbilu.uni.lu/handle/10993/910
http://orbilu.uni.lu/bitstream/10993/910/1/Feng_HE_PLAU_Treg_MSB%2C%202012.pdf">http://orbilu.uni.lu/bitstream/10993/910/1/Feng_HE_PLAU_Treg_MSB%2C%202012.pdf
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells.
Index Terms :
Adult; Aged; Antigens, CD3/analysis; Antigens, Neoplasm/immunology; CD8-Positive T-Lymphocytes/immunology; Extracellular Signal-Regulated MAP Kinases/metabolism; Female; Humans; Immunocompetence; MART-1 Antigen/immunology; Male; Middle Aged; Phosphorylation; STAT1 Transcription Factor/metabolism; STAT5 Transcription Factor/metabolism; Vaccination
info:eu-repo/semantics/article
article
URL :
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6D78EF0CB6629">http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6D78EF0CB6629
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.
Index Terms :
Animals
Antigens, CD44/metabolism
Cytokines/genetics/metabolism
Down-Regulation/genetics
Extracellular Signal-Regulated MAP Kinases/metabolism
Forkhead Transcription Factors
Gene Knockdown Techniques
Humans
L-Selectin/metabolism
MAP Kinase Signaling System
Mice
Mice, Knockout
STAT5 Transcription Factor/metabolism
Signal Transduction/genetics
T-Lymphocytes, Regulatory/enzymology/metabolism
Time Factors
Transcriptome/genetics
Urokinase-Type Plasminogen Activator/genetics/metabolism
info:eu-repo/semantics/article
URL :
http://orbilu.uni.lu/handle/10993/910">http://orbilu.uni.lu/handle/10993/910
http://orbilu.uni.lu/bitstream/10993/910/1/Feng_HE_PLAU_Treg_MSB%2C%202012.pdf">http://orbilu.uni.lu/bitstream/10993/910/1/Feng_HE_PLAU_Treg_MSB%2C%202012.pdf
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Thioredoxin-interacting protein suppresses bladder carcinogenesis.
Index Terms :
Aged
Animals
Blotting, Western
Butylhydroxybutylnitrosamine/toxicity
Carrier Proteins/genetics
Carrier Proteins/metabolism
Carrier Proteins/physiology
Chemokine CXCL12/genetics
Chemokine CXCL12/metabolism
Disease Models, Animal
Extracellular Signal-Regulated MAP Kinases/genetics
Extracellular Signal-Regulated MAP Kinases/metabolism
Female
Humans
Immunoenzyme Techniques
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Neoplasm Staging
Prognosis
RNA, Messenger/genetics
Receptors, CXCR4/antagonists & inhibitors
Receptors, CXCR4/genetics
Receptors, CXCR4/metabolism
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Survival Rate
Thioredoxins/metabolism
Thioredoxins/physiology
Urinary Bladder Neoplasms/chemically induced
Urinary Bladder Neoplasms/metabolism
Urinary Bladder Neoplasms/pathology
Journal Article
Źródło :
Carcinogenesis
URL :
http://hdl.handle.net/2433/158366">http://hdl.handle.net/2433/158366
10.1093/carcin/bgr137
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Adipokines identified as new downstream targets for adiponectin : lessons from adiponectin-overexpressing or -deficient mice.
Index Terms :
AMP-Activated Protein Kinases - metabolism
Adipocytes - cytology, physiology
Gene Expression - physiology
Glucose - metabolism
Inflammation - genetics, immunology, metabolism
Intercellular Signaling Peptides and Proteins - metabolism
Lipid Metabolism - physiology
Male
Metabolic Syndrome X - genetics, immunology, metabolism
Mice
Mice, Knockout
NF-kappa B - metabolism
Adiponectin - genetics, immunology, metabolism
Stromal Cells - cytology, physiology
Adipose Tissue - cytology, metabolism
Animals
Cells, Cultured
Cytokines - metabolism
Disease Models, Animal
Endothelial Cells - cytology, physiology
Extracellular Signal-Regulated MAP Kinases - metabolism
Inflammation
Adipocytes
Stromal-vascular cells
Secretome
info:eu-repo/semantics/article
URL :
http://hdl.handle.net/2078.1/109251">http://hdl.handle.net/2078.1/109251
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Adipokines identified as new downstream targets for adiponectin : lessons from adiponectin-overexpressing or -deficient mice.
Index Terms :
AMP-Activated Protein Kinases - metabolism
Adipocytes - cytology, physiology
Gene Expression - physiology
Glucose - metabolism
Inflammation - genetics, immunology, metabolism
Intercellular Signaling Peptides and Proteins - metabolism
Lipid Metabolism - physiology
Male
Metabolic Syndrome X - genetics, immunology, metabolism
Mice
Mice, Knockout
NF-kappa B - metabolism
Adiponectin - genetics, immunology, metabolism
Stromal Cells - cytology, physiology
Adipose Tissue - cytology, metabolism
Animals
Cells, Cultured
Cytokines - metabolism
Disease Models, Animal
Endothelial Cells - cytology, physiology
Extracellular Signal-Regulated MAP Kinases - metabolism
info:eu-repo/semantics/article
URL :
http://hdl.handle.net/2078.1/109251">http://hdl.handle.net/2078.1/109251
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Adipokines identified as new downstream targets for adiponectin : lessons from adiponectin-overexpressing or -deficient mice.
Index Terms :
AMP-Activated Protein Kinases - metabolism
Adipocytes - cytology, physiology
Gene Expression - physiology
Glucose - metabolism
Inflammation - genetics, immunology, metabolism
Intercellular Signaling Peptides and Proteins - metabolism
Lipid Metabolism - physiology
Male
Metabolic Syndrome X - genetics, immunology, metabolism
Mice
Mice, Knockout
NF-kappa B - metabolism
Adiponectin - genetics, immunology, metabolism
Stromal Cells - cytology, physiology
Adipose Tissue - cytology, metabolism
Animals
Cells, Cultured
Cytokines - metabolism
Disease Models, Animal
Endothelial Cells - cytology, physiology
Extracellular Signal-Regulated MAP Kinases - metabolism
info:eu-repo/semantics/article
URL :
http://hdl.handle.net/2078.1/109251">http://hdl.handle.net/2078.1/109251
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Tissue plasminogen activator prevents white matter damage following stroke.
Index Terms :
Sciences bio-médicales et agricoles
Aging
Animals
Apoptosis
Brain -- pathology
Brain Injuries -- pathology
Caspase 3 -- metabolism
Cell Lineage
Cytokines -- metabolism
Endothelium, Vascular -- cytology
Epidermal Growth Factor -- chemistry
Extracellular Signal-Regulated MAP Kinases -- metabolism
Humans
Mice
Mice, Inbred C57BL
Oligodendroglia -- cytology
Stroke -- pathology
Tissue Plasminogen Activator -- metabolism
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/148424">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/148424
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment.
Index Terms :
Analysis of Variance
Animals
Humans
Hyperthermia, Induced
Hypoxia-Inducible Factor 1 - metabolism
Immunohistochemistry
Lactic Acid - blood
Mice
NADPH Oxidase - metabolism
Neoplasms - metabolism, therapy
Protein-Serine-Threonine Kinases - metabolism
Reactive Oxygen Species - metabolism
Blotting, Western
Reverse Transcriptase Polymerase Chain Reaction
Vascular Endothelial Growth Factor A - metabolism
Cell Hypoxia - physiology
Cell Line, Tumor
DNA Primers - genetics
Enzyme-Linked Immunosorbent Assay
Extracellular Signal-Regulated MAP Kinases - metabolism
Female
Gene Expression Regulation - physiology
info:eu-repo/semantics/article
URL :
http://hdl.handle.net/2078.1/88185">http://hdl.handle.net/2078.1/88185
info:eu-repo/grantAgreement/EC/FP7/243188
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment.
Index Terms :
Analysis of Variance
Animals
Humans
Hyperthermia, Induced
Hypoxia-Inducible Factor 1 - metabolism
Immunohistochemistry
Lactic Acid - blood
Mice
NADPH Oxidase - metabolism
Neoplasms - metabolism, therapy
Protein-Serine-Threonine Kinases - metabolism
Reactive Oxygen Species - metabolism
Blotting, Western
Reverse Transcriptase Polymerase Chain Reaction
Vascular Endothelial Growth Factor A - metabolism
Cell Hypoxia - physiology
Cell Line, Tumor
DNA Primers - genetics
Enzyme-Linked Immunosorbent Assay
Extracellular Signal-Regulated MAP Kinases - metabolism
Female
Gene Expression Regulation - physiology
info:eu-repo/semantics/article
URL :
http://hdl.handle.net/2078.1/88185">http://hdl.handle.net/2078.1/88185
info:eu-repo/grantAgreement/EC/FP7/243188
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment.
Index Terms :
Analysis of Variance
Animals
Humans
Hyperthermia, Induced
Hypoxia-Inducible Factor 1 - metabolism
Immunohistochemistry
Lactic Acid - blood
Mice
NADPH Oxidase - metabolism
Neoplasms - metabolism, therapy
Protein-Serine-Threonine Kinases - metabolism
Reactive Oxygen Species - metabolism
Blotting, Western
Reverse Transcriptase Polymerase Chain Reaction
Vascular Endothelial Growth Factor A - metabolism
Cell Hypoxia - physiology
Cell Line, Tumor
DNA Primers - genetics
Enzyme-Linked Immunosorbent Assay
Extracellular Signal-Regulated MAP Kinases - metabolism
Female
Gene Expression Regulation - physiology
info:eu-repo/semantics/article
URL :
http://hdl.handle.net/2078.1/88185">http://hdl.handle.net/2078.1/88185
info:eu-repo/grantAgreement/EC/FP7/243188
Zasób elektroniczny
Szczegóły
Podgląd okładki
Tytuł :
Crosstalks between the receptors tyrosine kinase EGFR and TrkA and the GPCR, FPR, in human monocytes are essential for receptors-mediated cell activation.
Index Terms :
Sciences bio-médicales et agricoles
Antigens, CD11b -- metabolism
Epidermal Growth Factor -- pharmacology
Extracellular Signal-Regulated MAP Kinases -- metabolism
Gene Knockdown Techniques
Humans
Hydrogen Peroxide -- metabolism
Monocytes -- enzymology
Monocytes -- metabolism
N-Formylmethionine Leucyl-Phenylalanine -- pharmacology
Nerve Growth Factor -- pharmacology
Receptor Cross-Talk
Receptor, Epidermal Growth Factor -- antagonists & inhibitors
Receptor, Epidermal Growth Factor -- genetics
Receptor, Epidermal Growth Factor -- metabolism
Receptor, trkA -- antagonists & inhibitors
Receptor, trkA -- genetics
Receptor, trkA -- metabolism
Receptors, Formyl Peptide -- antagonists & inhibitors
Receptors, Formyl Peptide -- genetics
Receptors, Formyl Peptide -- metabolism
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
URL :
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/73192">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/73192
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Zasób elektroniczny
Szczegóły
Wyświetlanie 1-20 z 45

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