Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""FIBROBLASTS"" wg kryterium: Temat


Tytuł :
Generation and Characterization of a Tumor Stromal Microenvironment and Analysis of Its Interplay with Breast Cancer Cells: An In Vitro Model to Study Breast Cancer-Associated Fibroblast Inactivation.
Autorzy :
Romano V; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Ruocco MR; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
Carotenuto P; TIGEM, Telethon Institute of Genetics and Medicine, 80078 Naples, Italy.; Medical Genetics, Department of Translational Medical Science, University of Naples Federico II, 80131 Naples, Italy.
Barbato A; TIGEM, Telethon Institute of Genetics and Medicine, 80078 Naples, Italy.
Venuta A; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Acampora V; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
De Lella S; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Vigliar E; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Iaccarino A; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Troncone G; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Calì G; IEOS Istituto di Endocrinologia e Oncologia Sperimentale 'G. Salvatore', National Council of Research, 80131 Naples, Italy.
Insabato L; Anatomic Pathology Unit, Department of Advanced Biomedical Sciences, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.
Russo D; Anatomic Pathology Unit, Department of Advanced Biomedical Sciences, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.
Franco B; TIGEM, Telethon Institute of Genetics and Medicine, 80078 Naples, Italy.; Medical Genetics, Department of Translational Medical Science, University of Naples Federico II, 80131 Naples, Italy.; Scuola Superiore Meridionale, School for Advanced Studies, 80138 Naples, Italy.
Masone S; Department of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.
Velotti N; Department of Advanced Biochemical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Accurso A; Department of General, Oncological, Bariatric and Endocrine-Metabolic Surgery, University of Naples Federico II, 80131 Naples, Italy.
Pellegrino T; DAI Chirurgia Generale, Endocrinologia, Ortopedia e Riabilitazione, Azienda Ospedaliera Universitaria Federico II, 80131 Naples, Italy.
Fiume G; Department of Experimental and Clinical Medicine, University 'Magna Graecia' of Catanzaro, 88100 Catanzaro, Italy.
Belviso I; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Montagnani S; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Avagliano A; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Arcucci A; Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 20; Vol. 23 (12). Date of Electronic Publication: 2022 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms*/metabolism
Cancer-Associated Fibroblasts*/metabolism
Cell Line, Tumor ; Culture Media, Conditioned/metabolism ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Female ; Fibroblasts/metabolism ; Humans ; Inflammation/pathology ; Stromal Cells/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Alpha-smooth muscle actin-positive cancer-associated fibroblasts secreting osteopontin promote growth of luminal breast cancer.
Autorzy :
Muchlińska A; Laboratory of Translational Oncology, Intercollegiate Faculty of Biotechnology, Medical University of Gdansk, 80-211, Gdansk, Poland.
Nagel A; Laboratory of Translational Oncology, Intercollegiate Faculty of Biotechnology, Medical University of Gdansk, 80-211, Gdansk, Poland.
Popęda M; Laboratory of Translational Oncology, Intercollegiate Faculty of Biotechnology, Medical University of Gdansk, 80-211, Gdansk, Poland.
Szade J; Department of Pathomorphology, Medical University of Gdansk, 80-214, Gdansk, Poland.
Niemira M; Clinical Research Centre, Medical University of Bialystok, 15-276, Bialystok, Poland.
Zieliński J; Department of Surgical Oncology, Medical University of Gdansk, 80-214, Gdansk, Poland.
Skokowski J; Department of Surgical Oncology, Medical University of Gdansk, 80-214, Gdansk, Poland.; Biobanking and Biomolecular Resources Research Infrastructure Poland (BBMRI.PL), 80-211, Gdansk, Poland.
Bednarz-Knoll N; Laboratory of Translational Oncology, Intercollegiate Faculty of Biotechnology, Medical University of Gdansk, 80-211, Gdansk, Poland.
Żaczek AJ; Laboratory of Translational Oncology, Intercollegiate Faculty of Biotechnology, Medical University of Gdansk, 80-211, Gdansk, Poland. .
Pokaż więcej
Źródło :
Cellular & molecular biology letters [Cell Mol Biol Lett] 2022 Jun 11; Vol. 27 (1), pp. 45. Date of Electronic Publication: 2022 Jun 11.
Typ publikacji :
Letter
MeSH Terms :
Breast Neoplasms*/pathology
Cancer-Associated Fibroblasts*/chemistry
Cancer-Associated Fibroblasts*/metabolism
Cancer-Associated Fibroblasts*/pathology
Actins/metabolism ; Cell Line, Tumor ; Culture Media, Conditioned/pharmacology ; Female ; Fibroblasts/metabolism ; Humans ; Muscle, Smooth/chemistry ; Muscle, Smooth/metabolism ; Muscle, Smooth/pathology ; Osteopontin/genetics ; Osteopontin/metabolism
Opinia redakcyjna
Tytuł :
'Reverse Warburg effect' of cancer‑associated fibroblasts (Review).
Autorzy :
Liang L; NHC Key Laboratory of Carcinogenesis and Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, P.R. China.
Li W; NHC Key Laboratory of Carcinogenesis and Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, P.R. China.
Li X; Department of General Surgery, Breast Cancer Center, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Jin X; NHC Key Laboratory of Carcinogenesis and Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, P.R. China.
Liao Q; NHC Key Laboratory of Carcinogenesis and Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, P.R. China.
Li Y; Department of Nuclear Medicine, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, P.R. China.
Zhou Y; NHC Key Laboratory of Carcinogenesis and Hunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, P.R. China.
Pokaż więcej
Źródło :
International journal of oncology [Int J Oncol] 2022 Jun; Vol. 60 (6). Date of Electronic Publication: 2022 Apr 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cancer-Associated Fibroblasts*
Neoplasms*/pathology
Fibroblasts/metabolism ; Glycolysis ; Humans ; Oxidative Phosphorylation ; Stromal Cells/pathology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Cancer-associated fibroblasts at the unfavorable desmoplastic stroma promote colorectal cancer aggressiveness: Potential role of ADAM9.
Autorzy :
Ao T; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Mochizuki S; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Kajiwara Y; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Yonemura K; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Shiraishi T; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Nagata K; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Shinto E; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Okamoto K; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Nearchou IP; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Shimazaki H; Department of Laboratory Medicine, National Defence Medical College, Tokorozawa, Japan.
Kishi Y; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Okada Y; Department of Pathophysiology for Locomotive and Neoplastic Diseases, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ueno H; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Pokaż więcej
Źródło :
International journal of cancer [Int J Cancer] 2022 May 15; Vol. 150 (10), pp. 1706-1721. Date of Electronic Publication: 2022 Feb 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Colorectal Neoplasms*/metabolism
ADAM Proteins ; Animals ; Fibroblasts/pathology ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Neoplasm Recurrence, Local/pathology ; Prognosis ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
The lactate-NAD axis activates cancer-associated fibroblasts by downregulating p62.
Autorzy :
Linares JF; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Cid-Diaz T; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Duran A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Osrodek M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Martinez-Ordoñez A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Reina-Campos M; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Kuo HH; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Elemento O; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Martin ML; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Cordes T; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Thompson TC; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Metallo CM; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Moscat J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: .
Diaz-Meco MT; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: .
Pokaż więcej
Źródło :
Cell reports [Cell Rep] 2022 May 10; Vol. 39 (6), pp. 110792.
Typ publikacji :
Journal Article
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Neoplasms*/metabolism
Fibroblasts/metabolism ; Lactic Acid/metabolism ; NAD/metabolism ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Poly(ADP-ribose) Polymerases/metabolism
Czasopismo naukowe
Tytuł :
CAF promotes chemoresistance through NRP2 in gastric cancer.
Autorzy :
Yang Y; Department of Gastroenterology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, China.
Ma Y; Department of Endoscopic Center, Peking University First Hospital, Beijing, China.
Yan S; Department of Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Wang P; Department of Gastroenterology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, China.
Hu J; Department of Gastroenterology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, China.
Chen S; Department of Gastroenterology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, China.
Zhu J; Department of Gastroenterology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, China.
Wang J; Department of Gastroenterology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, China.
Chen G; Department of Gastroenterology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, China.
Liu Y; Department of Gastroenterology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing, China. .
Pokaż więcej
Źródło :
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association [Gastric Cancer] 2022 May; Vol. 25 (3), pp. 503-514. Date of Electronic Publication: 2021 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Cancer-Associated Fibroblasts*/pathology
Stomach Neoplasms*/pathology
Cell Line, Tumor ; Cell Proliferation/physiology ; Drug Resistance, Neoplasm ; Fibroblasts/pathology ; Fluorouracil/pharmacology ; Humans ; RNA/metabolism
Czasopismo naukowe
Tytuł :
Phenotypic heterogeneity, stability and plasticity in tumor-promoting carcinoma-associated fibroblasts.
Autorzy :
Mezawa Y; Department of Pathology and Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Orimo A; Department of Pathology and Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Pokaż więcej
Źródło :
The FEBS journal [FEBS J] 2022 May; Vol. 289 (9), pp. 2429-2447. Date of Electronic Publication: 2021 Apr 12.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Carcinoma*/metabolism
Fibroblasts/metabolism ; Humans ; Phenotype ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł :
Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer.
Autorzy :
Huang H; Department of Surgery, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA. Electronic address: .
Wang Z; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Zhang Y; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA; Cancer Biology Graduate Program, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA.
Pradhan RN; Genentech, South San Francisco, CA 94080, USA.
Ganguly D; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA; Cancer Biology Graduate Program, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA.
Chandra R; Department of Surgery, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA.
Murimwa G; Department of Surgery, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA.
Wright S; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA.
Gu X; Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA.
Maddipati R; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA.
Müller S; Genentech, South San Francisco, CA 94080, USA.
Turley SJ; Genentech, South San Francisco, CA 94080, USA.
Brekken RA; Department of Surgery, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA; Cancer Biology Graduate Program, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA; Department of Pharmacology, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390, USA. Electronic address: .
Pokaż więcej
Źródło :
Cancer cell [Cancer Cell] 2022 Jun 13; Vol. 40 (6), pp. 656-673.e7. Date of Electronic Publication: 2022 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Pancreatic Neoplasms*/pathology
Fibroblasts ; Humans ; T-Lymphocytes, Regulatory ; Transforming Growth Factor beta/metabolism
SCR Disease Name :
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł :
Biological features of canine cancer-associated fibroblasts and their influence on cancer cell invasion.
Autorzy :
Kudo A; Laboratory of Advanced Veterinary Medicine, Department of Veterinary Clinical Sciences Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.; Laboratory of Small Animal Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan.
Yoshimoto S; Laboratory of Advanced Veterinary Medicine, Department of Veterinary Clinical Sciences Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.; Laboratory of Small Animal Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan.
Yoshida H; Laboratory of Advanced Veterinary Medicine, Department of Veterinary Clinical Sciences Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.
Izumi Y; Laboratory of Advanced Veterinary Medicine, Department of Veterinary Clinical Sciences Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.
Takagi S; Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.; Laboratory of Small Animal Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan.
Pokaż więcej
Źródło :
The Journal of veterinary medical science [J Vet Med Sci] 2022 Jun 10; Vol. 84 (6), pp. 784-791. Date of Electronic Publication: 2022 Apr 11.
Typ publikacji :
Journal Article
MeSH Terms :
Cancer-Associated Fibroblasts*
Dog Diseases*/pathology
Animals ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Dogs ; Fibroblasts/metabolism ; Neoplasm Invasiveness/pathology
Czasopismo naukowe
Tytuł :
Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer.
Autorzy :
McAndrews KM; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Chen Y; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Darpolor JK; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Zheng X; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Yang S; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Carstens JL; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Li B; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Wang H; Department of Anatomical Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Miyake T; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Correa de Sampaio P; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Kirtley ML; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Natale M; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Wu CC; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Sugimoto H; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
LeBleu VS; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Feinberg School of Medicine, Northwestern University, Chicago, Illinois.; Kellogg School of Management, Northwestern University, Evanston, Illinois.
Kalluri R; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Bioengineering, Rice University, Houston, Texas.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
Pokaż więcej
Źródło :
Cancer discovery [Cancer Discov] 2022 Jun 02; Vol. 12 (6), pp. 1580-1597.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Carcinoma, Pancreatic Ductal*/drug therapy
Carcinoma, Pancreatic Ductal*/genetics
Carcinoma, Pancreatic Ductal*/metabolism
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Animals ; Cell Line, Tumor ; Fibroblasts/metabolism ; Humans ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Interleukin-6/therapeutic use ; Mice ; Tumor Microenvironment
SCR Disease Name :
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł :
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression.
Autorzy :
Verginadis II; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Avgousti H; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Monslow J; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Skoufos G; Department of Electrical and Computer Engineering, University of Thessaly, Volos, Greece.; Hellenic Pasteur Institute, Athens, Greece.
Chinga F; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kim K; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Leli NM; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Karagounis IV; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Bell BI; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, NY, USA.
Velalopoulou A; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Salinas CS; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Wu VS; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Li Y; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Ye J; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Scott DA; Cancer Metabolism Core, Sanford-Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Osterman AL; Cancer Metabolism Core, Sanford-Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Sengupta A; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute of Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Weljie A; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute of Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Huang M; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Zhang D; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Fan Y; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Radaelli E; Department of Pathobiology, School of Veterinary Medicine, Comparative Pathology Core, University of Pennsylvania, Philadelphia, PA, USA.
Tobias JW; Penn Genomic Analysis Core, Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Rambow F; Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, KU Leuven, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.
Karras P; Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, KU Leuven, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.
Marine JC; Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, KU Leuven, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.
Xu X; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Hatzigeorgiou AG; Department of Electrical and Computer Engineering, University of Thessaly, Volos, Greece.; Hellenic Pasteur Institute, Athens, Greece.; DIANA-Lab, Department of Computer Science and Biomedical Informatics, University of Thessaly, Lamia, Greece.
Ryeom S; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Surgery, Columbia University Irving Medical Center, New York, NY, USA.
Diehl JA; Department of Biochemistry, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Fuchs SY; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Puré E; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Koumenis C; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. .
Pokaż więcej
Źródło :
Nature cell biology [Nat Cell Biol] 2022 Jun; Vol. 24 (6), pp. 940-953. Date of Electronic Publication: 2022 Jun 02.
Typ publikacji :
Journal Article
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Melanoma*/genetics
Pancreatic Neoplasms*/pathology
Animals ; Collagen/metabolism ; Fibroblasts/metabolism ; Gene Expression Regulation, Neoplastic ; Mice ; Mice, Knockout ; Neovascularization, Pathologic/metabolism
Czasopismo naukowe
Tytuł :
HIF-2 in Cancer-Associated Fibroblasts Polarizes Macrophages and Creates an Immunosuppressive Tumor Microenvironment in Pancreatic Cancer.
Autorzy :
Ramakrishnan S; Department of Surgery, Miller School of Medicine, Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida. Electronic address: .
Pokaż więcej
Źródło :
Gastroenterology [Gastroenterology] 2022 Jun; Vol. 162 (7), pp. 1835-1837. Date of Electronic Publication: 2022 Mar 28.
Typ publikacji :
Editorial
MeSH Terms :
Cancer-Associated Fibroblasts*/pathology
Pancreatic Neoplasms*/pathology
Basic Helix-Loop-Helix Transcription Factors ; Cell Line, Tumor ; Fibroblasts/pathology ; Humans ; Macrophages/pathology ; Tumor Microenvironment
SCR Disease Name :
Pancreatic Carcinoma
Opinia redakcyjna
Tytuł :
PRRX1 is a master transcription factor of stromal fibroblasts for myofibroblastic lineage progression.
Autorzy :
Lee KW; Department of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, 06351, Republic of Korea.
Yeo SY; Department of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, 06351, Republic of Korea.
Gong JR; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Koo OJ; ToolGen Inc., Gasan digital 1-ro, Geumcheon, Seoul, 08594, Republic of Korea.
Sohn I; Arontier Inc., Gangnam-daero, Seoul, Republic of Korea.
Lee WY; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Kim HC; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Yun SH; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Cho YB; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Choi MA; Department of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, 06351, Republic of Korea.
An S; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Kim J; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Sung CO; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. .
Cho KH; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea. .
Kim SH; Department of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, 06351, Republic of Korea. .; Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. .; Single Cell Network Research Center, Sungkyunkwan University School of Medicine, Suwon, Gyeonggi-do, 16419, Republic of Korea. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2022 May 19; Vol. 13 (1), pp. 2793. Date of Electronic Publication: 2022 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Neoplasms*/metabolism
Animals ; Fibroblasts/metabolism ; Mice ; Myofibroblasts ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Galectin-1 orchestrates an inflammatory tumor-stroma crosstalk in hepatoma by enhancing TNFR1 protein stability and signaling in carcinoma-associated fibroblasts.
Autorzy :
Tsai YT; International PhD Program for Translational Science, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Translational Medicine, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan.
Li CY; International PhD Program for Translational Science, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Translational Medicine, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan.
Huang YH; Graduate Institute of Translational Medicine, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan.; Department of Biochemistry and Molecular Cell Biology, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan.
Chang TS; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Lin CY; Institute of Information Science, Academia Sinica, Taipei, Taiwan.
Chuang CH; Institute of Information Science, Academia Sinica, Taipei, Taiwan.
Wang CY; Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taipei, Taiwan.
Anuraga G; Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taipei, Taiwan.
Chang TH; Graduate Institute of Biomedical Informatics, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan.
Shih TC; Department of Biochemistry and Molecular Medicine, University of California, Davis, Sacramento, CA, USA.
Lin ZY; Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Faculty of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chen YL; Institute of Oral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chung I; Universiti Malaya Cancer Research Institute, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, 50603, Malaysia.; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, 50603, Malaysia.
Lee KH; Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taipei, Taiwan.
Chang CC; International PhD Program for Translational Science, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Translational Medicine, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan.
Sung SY; International PhD Program for Translational Science, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Translational Medicine, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan.
Yang KH; International PhD Program for Translational Science, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Translational Medicine, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan.
Tsui WL; International PhD Program for Translational Science, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Translational Medicine, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan.
Yap CV; International PhD Program for Translational Science, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Translational Medicine, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan.
Wu MH; International PhD Program for Translational Science, Taipei Medical University, Taipei, Taiwan. .; Graduate Institute of Translational Medicine, College of Medical Sciences and Technology, Taipei Medical University, Taipei, Taiwan. .; Center for Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan. .; TMU Research Center of Cancer Translational Medicine, Taipei, Taiwan. .
Pokaż więcej
Źródło :
Oncogene [Oncogene] 2022 May; Vol. 41 (21), pp. 3011-3023. Date of Electronic Publication: 2022 Apr 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Cell Line, Tumor ; Fibroblasts/metabolism ; Galectin 1/genetics ; Galectin 1/metabolism ; Humans ; Protein Stability ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Microfluidic one-directional interstitial flow generation from cancer to cancer associated fibroblast.
Autorzy :
Kim J; School of Mechanical Engineering, Korea University, Seoul, 02841, Korea; George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, United States.
Park H; School of Mechanical Engineering, Korea University, Seoul, 02841, Korea.
Kim H; School of Mechanical Engineering, Korea University, Seoul, 02841, Korea; Center for Systems Biology, Massachusetts General Hospital, Boston, MA, 02114, United States.
Kim Y; George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, United States; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332, United States; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, United States; Institute for Electronics and Nanotechnology, Georgia Institute of Technology, Atlanta, GA 30332, United States.
Oh HJ; School of Mechanical Engineering, Korea University, Seoul, 02841, Korea. Electronic address: .
Chung S; School of Mechanical Engineering, Korea University, Seoul, 02841, Korea; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Korea. Electronic address: .
Pokaż więcej
Źródło :
Acta biomaterialia [Acta Biomater] 2022 May; Vol. 144, pp. 258-265. Date of Electronic Publication: 2022 Mar 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Neoplasms*/pathology
Cell Line, Tumor ; Fibroblasts/metabolism ; Humans ; Hydrogels/metabolism ; Microfluidics ; Tumor Microenvironment/physiology ; Vimentin/metabolism
Czasopismo naukowe
Tytuł :
Crosstalk between cancer-associated fibroblasts and immune cells in peritoneal metastasis: inhibition in the migration of M2 macrophages and mast cells by Tranilast.
Autorzy :
Nakamura Y; Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.
Kinoshita J; Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan. .
Yamaguchi T; Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.
Aoki T; Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.
Saito H; Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.
Hamabe-Horiike T; Center for Biomedical Research and Education, School of Medicine, Kanazawa University, Kanazawa, Japan.
Harada S; Center for Biomedical Research and Education, School of Medicine, Kanazawa University, Kanazawa, Japan.
Nomura S; Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Inaki N; Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.
Fushida S; Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.
Pokaż więcej
Źródło :
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association [Gastric Cancer] 2022 May; Vol. 25 (3), pp. 515-526. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji :
Journal Article
MeSH Terms :
Cancer-Associated Fibroblasts*/pathology
Peritoneal Neoplasms*/metabolism
Stomach Neoplasms*/pathology
Animals ; Cell Line, Tumor ; Cell Proliferation ; Fibroblasts/pathology ; Fibrosis ; Humans ; Macrophages/pathology ; Mast Cells ; Mice ; Mice, Inbred C57BL ; Tumor Microenvironment ; ortho-Aminobenzoates
Czasopismo naukowe
Tytuł :
Cancer-associated fibroblasts in colorectal cancer.
Autorzy :
Kamali Zonouzi S; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Pezeshki PS; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Razi S; Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Tehran, Iran.; School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Rezaei N; Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Dr Qarib St, Keshavarz Blvd, 14194, Tehran, Iran. .; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. .; Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Stockholm, Sweden. .
Pokaż więcej
Źródło :
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2022 May; Vol. 24 (5), pp. 757-769. Date of Electronic Publication: 2021 Nov 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Colorectal Neoplasms*/pathology
Carboxypeptidases/metabolism ; Carcinogenesis/pathology ; Fibroblasts/metabolism ; Humans ; Prognosis ; Repressor Proteins/metabolism ; Transforming Growth Factor beta/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Metastatic colorectal carcinoma-associated fibroblasts have immunosuppressive properties related to increased IGFBP2 expression.
Autorzy :
Walterskirchen N; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Müller C; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Ramos C; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Zeindl S; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Stang S; Institute of Medical Genetics, Medical University of Vienna, Waehringer Straße 10, A-1090, Vienna, Austria.
Herzog D; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Sachet M; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Schimek V; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Unger L; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Gerakopoulos V; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Hengstschläger M; Institute of Medical Genetics, Medical University of Vienna, Waehringer Straße 10, A-1090, Vienna, Austria.
Bachleitner-Hofmann T; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Bergmann M; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Dolznig H; Institute of Medical Genetics, Medical University of Vienna, Waehringer Straße 10, A-1090, Vienna, Austria. Electronic address: .
Oehler R; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria. Electronic address: .
Pokaż więcej
Źródło :
Cancer letters [Cancer Lett] 2022 Aug 01; Vol. 540, pp. 215737. Date of Electronic Publication: 2022 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Colorectal Neoplasms*/pathology
Cell Movement/genetics ; Cell Proliferation/genetics ; Fibroblasts/metabolism ; Humans ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł :
Crosstalk of tumor stromal cells orchestrates invasion and spreading of gastric cancer.
Autorzy :
Tanaka M; Department of Molecular Medicine and Biochemistry, Akita University Graduate School of Medicine, Akita, Japan.
Pokaż więcej
Źródło :
Pathology international [Pathol Int] 2022 Apr; Vol. 72 (4), pp. 219-233. Date of Electronic Publication: 2022 Feb 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Stomach Neoplasms*/pathology
Cell Line, Tumor ; Fibroblasts/pathology ; Humans ; Stromal Cells/pathology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
A CFH peptide-decorated liposomal oxymatrine inactivates cancer-associated fibroblasts of hepatocellular carcinoma through epithelial-mesenchymal transition reversion.
Autorzy :
Guo J; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China.; Jiangsu Province Academy of Traditional Chinese Medicine, 100 Shizi Road, Nanjing, 210028, China.; Anhui Province Key Laboratory of Pharmaceutical Preparation Technology and Application, Engineering Technology Research Center of Modern Pharmaceutical Preparation, College of Pharmacy, Anhui University of Chinese Medicine, 230012, Hefei, China.
Zeng H; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China.
Shi X; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China.
Han T; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China.
Liu Y; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China.
Liu Y; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China.; Jiangsu Province Academy of Traditional Chinese Medicine, 100 Shizi Road, Nanjing, 210028, China.
Liu C; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China.; Jiangsu Province Academy of Traditional Chinese Medicine, 100 Shizi Road, Nanjing, 210028, China.
Qu D; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China. .; Jiangsu Province Academy of Traditional Chinese Medicine, 100 Shizi Road, Nanjing, 210028, China. .
Chen Y; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China. .; Jiangsu Province Academy of Traditional Chinese Medicine, 100 Shizi Road, Nanjing, 210028, China. .
Pokaż więcej
Źródło :
Journal of nanobiotechnology [J Nanobiotechnology] 2022 Mar 05; Vol. 20 (1), pp. 114. Date of Electronic Publication: 2022 Mar 05.
Typ publikacji :
Journal Article
MeSH Terms :
Cancer-Associated Fibroblasts*
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Alkaloids ; Animals ; Cell Line, Tumor ; Epithelial-Mesenchymal Transition/physiology ; Fibroblasts/metabolism ; Humans ; Mice ; Peptides/metabolism ; Peptides/pharmacology ; Quinolizines ; Tumor Microenvironment
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies