Information

Dear user, the application need JavaScript support. Please enable JavaScript in your browser.

You search for a phrase ""FIBROBLASTS"" according to the criterion: Subject Terms


Title:
Disruption of LPA-LPAR1 pathway results in lung tumor growth inhibition by downregulating B7-H3 expression in fibroblasts.
Authors:
Meng F; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Yin Z; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Lu F; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Wang W; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Zhang H; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Show more
Source:
Thoracic cancer [Thorac Cancer] 2024 Feb; Vol. 15 (4), pp. 316-326. Date of Electronic Publication: 2023 Dec 20.
Publication Type:
Journal Article
MeSH Terms:
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Cancer-Associated Fibroblasts*/metabolism
Humans ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Signal Transduction ; Cell Proliferation ; Transcription Factors ; Tumor Microenvironment ; B7 Antigens/genetics ; B7 Antigens/pharmacology ; Receptors, Lysophosphatidic Acid/genetics ; Receptors, Lysophosphatidic Acid/metabolism
Academic Journal
Title:
The miR-1290/OGN axis in ovarian cancer-associated fibroblasts modulates cancer cell proliferation and invasion.
Authors:
Jiang B; Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, NO.138 Tongzipo Road, Yuelu District, Changsha, Hunan, 410013, China.
Xiao S; Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, NO.138 Tongzipo Road, Yuelu District, Changsha, Hunan, 410013, China.
Zhang S; Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, NO.138 Tongzipo Road, Yuelu District, Changsha, Hunan, 410013, China.
Xiao F; Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, NO.138 Tongzipo Road, Yuelu District, Changsha, Hunan, 410013, China. .
Show more
Source:
Journal of ovarian research [J Ovarian Res] 2024 Feb 24; Vol. 17 (1), pp. 52. Date of Electronic Publication: 2024 Feb 24.
Publication Type:
Journal Article
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Ovarian Neoplasms*/pathology
Animals ; Mice ; Humans ; Female ; Proto-Oncogene Proteins c-akt/metabolism ; Cell Line, Tumor ; Fibroblasts ; Cell Proliferation/genetics ; TOR Serine-Threonine Kinases/metabolism ; Cell Movement/genetics ; DNA ; Gene Expression Regulation, Neoplastic ; Intercellular Signaling Peptides and Proteins/genetics
Academic Journal
Title:
Dual effect of vitamin D 3 on breast cancer-associated fibroblasts.
Authors:
Łabędź N; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Weigla 12, 53-114, Wroclaw, Poland. .; Łukasiewicz Research Network-PORT Polish Center for Technology Development, Stabłowicka 147, 54-066, Wrocław, Poland. .
Anisiewicz A; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Weigla 12, 53-114, Wroclaw, Poland.
Stachowicz-Suhs M; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Weigla 12, 53-114, Wroclaw, Poland.
Banach J; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Weigla 12, 53-114, Wroclaw, Poland.
Kłopotowska D; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Weigla 12, 53-114, Wroclaw, Poland.
Maciejczyk A; Department of Oncology, Wroclaw Medical University, Pl. Ludwika Hirszfelda 12, 53-413, Wroclaw, Poland.; Lower Silesian Oncology, Pulmonology and Hematology Center, Pl. Ludwika Hirszfelda 12, 53-413, Wroclaw, Poland.
Gazińska P; Łukasiewicz Research Network-PORT Polish Center for Technology Development, Stabłowicka 147, 54-066, Wrocław, Poland.; Research Oncology, Division of Cancer Studies, Great Maze Pond, King's College London, London, SE1 3SS, UK.
Piotrowska A; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Ul., Chałubińskiego 6a, 50-368, Wroclaw, Poland.
Dzięgiel P; Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Ul., Chałubińskiego 6a, 50-368, Wroclaw, Poland.
Matkowski R; Department of Oncology, Wroclaw Medical University, Pl. Ludwika Hirszfelda 12, 53-413, Wroclaw, Poland.; Lower Silesian Oncology, Pulmonology and Hematology Center, Pl. Ludwika Hirszfelda 12, 53-413, Wroclaw, Poland.
Wietrzyk J; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Weigla 12, 53-114, Wroclaw, Poland.
Show more
Source:
BMC cancer [BMC Cancer] 2024 Feb 15; Vol. 24 (1), pp. 209. Date of Electronic Publication: 2024 Feb 15.
Publication Type:
Journal Article
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Humans ; Female ; Matrix Metalloproteinase 9/metabolism ; Matrix Metalloproteinase 2/metabolism ; Vitamin D3 24-Hydroxylase/genetics ; Vitamin D3 24-Hydroxylase/metabolism ; Cholecalciferol ; Calcitriol/pharmacology ; Fibroblasts/metabolism ; Cell Movement/genetics ; Cell Line, Tumor ; Tumor Microenvironment/genetics
Academic Journal
Title:
Glioblastoma-Associated Mesenchymal Stem/Stromal Cells and Cancer-Associated Fibroblasts: Partners in Crime?
Authors:
Lootens T; 4Brain, Department of Head and Skin, Ghent University, 9000 Ghent, Belgium.; Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), 9000 Ghent, Belgium.
Roman BI; Cancer Research Institute Ghent (CRIG), 9000 Ghent, Belgium.; SynBioC, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium.
Stevens CV; Cancer Research Institute Ghent (CRIG), 9000 Ghent, Belgium.; SynBioC, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium.
De Wever O; Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), 9000 Ghent, Belgium.
Raedt R; 4Brain, Department of Head and Skin, Ghent University, 9000 Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), 9000 Ghent, Belgium.
Show more
Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 14; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 14.
Publication Type:
Journal Article; Review
MeSH Terms:
Glioblastoma*/metabolism
Cancer-Associated Fibroblasts*
Mesenchymal Stem Cells*/metabolism
Humans ; Signal Transduction ; Crime ; Tumor Microenvironment ; Fibroblasts/pathology
Academic Journal
Title:
Tubulointerstitial nephritis antigen-like 1 from cancer-associated fibroblasts contribute to the progression of diffuse-type gastric cancers through the interaction with integrin β1.
Authors:
Lee D; Department of Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.; Cancer Biology Graduate Program, Ajou University School of Medicine Suwon, Suwon, Republic of Korea.; AI-Super Convergence KIURI Translational Research Center, Ajou University School of Medicine, Suwon, Republic of Korea.
Ham IH; Department of Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.; Inflamm-Aging Translational Research Center, Ajou University School of Medicine, Suwon, Republic of Korea.
Oh HJ; Department of Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.
Lee DM; Inflamm-Aging Translational Research Center, Ajou University School of Medicine, Suwon, Republic of Korea.
Yoon JH; Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Functional RNomics Research Center, College of Medicine, The Catholic University of Korea Seoul, Seoul, Republic of Korea.
Son SY; Department of Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.
Kim TM; Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Cancer Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Biomedicine and Health Science, Graduate School, The Catholic University of Korea, Seoul, Republic of Korea.
Kim JY; Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Daejeon, Republic of Korea.
Han SU; Department of Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.
Hur H; Department of Surgery, Ajou University School of Medicine, Suwon, Republic of Korea. .; Cancer Biology Graduate Program, Ajou University School of Medicine Suwon, Suwon, Republic of Korea. .; Inflamm-Aging Translational Research Center, Ajou University School of Medicine, Suwon, Republic of Korea. .
Show more
Source:
Journal of translational medicine [J Transl Med] 2024 Feb 14; Vol. 22 (1), pp. 154. Date of Electronic Publication: 2024 Feb 14.
Publication Type:
Journal Article
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
Nephritis, Interstitial*/metabolism
Nephritis, Interstitial*/pathology
Stomach Neoplasms*/pathology
Animals ; Humans ; Cell Line, Tumor ; Cell Movement/genetics ; Fibroblasts/metabolism ; Integrin beta1/genetics ; Integrin beta1/metabolism ; RNA, Small Interfering/metabolism ; Tumor Microenvironment
Academic Journal
Title:
Characterization of gastric cancer-stimulated signaling pathways and function of CTGF in cancer-associated fibroblasts.
Authors:
Choi KM; Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Daejeon, South Korea.
Kim B; Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Daejeon, South Korea.
Lee SM; Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Daejeon, South Korea.
Han J; Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Daejeon, South Korea.
Bae HS; Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Daejeon, South Korea.
Han SB; Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Daejeon, South Korea.
Lee D; Department of Surgery, Ajou University School of Medicine, Suwon, South Korea.; Inflamm-Aging Translational Research Center, Ajou University School of Medicine, Suwon, South Korea.; AI-Super Convergence KIURI Translational Research Center, Suwon, South Korea.
Ham IH; Department of Surgery, Ajou University School of Medicine, Suwon, South Korea.; Inflamm-Aging Translational Research Center, Ajou University School of Medicine, Suwon, South Korea.
Hur H; Department of Surgery, Ajou University School of Medicine, Suwon, South Korea.; Inflamm-Aging Translational Research Center, Ajou University School of Medicine, Suwon, South Korea.
Kim E; Natural Product Informatics Center, Korea Institute of Science and Technology (KIST), Gangneung, South Korea.
Kim JY; Graduate School of Analytical Science and Technology (GRAST), Chungnam National University, Daejeon, South Korea. .
Show more
Source:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jan 02; Vol. 22 (1), pp. 8. Date of Electronic Publication: 2024 Jan 02.
Publication Type:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
Connective Tissue Growth Factor*/metabolism
Stomach Neoplasms*/metabolism
Humans ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Fibroblasts/metabolism ; Protein-Tyrosine Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; Tumor Microenvironment
Academic Journal
Title:
circNOX4 activates an inflammatory fibroblast niche to promote tumor growth and metastasis in NSCLC via FAP/IL-6 axis.
Authors:
Zhao Y; Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China.; Department of Oncology, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050011, China.
Jia Y; Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China.
Wang J; Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China.
Chen X; Department of Nuclear Medicine, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050011, China.
Han J; Department of Nuclear Medicine, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050011, China.
Zhen S; Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China.
Yin S; Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China.
Lv W; Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China.
Yu F; Department of Thoracic Surgery, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050011, China.
Wang J; Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China.
Xu F; Departments of Oncology, The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China.
Zhao X; Department of Nuclear Medicine, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050011, China. .; Hebei Provincial Key Laboratory of Tumor Microenvironment and Drug Resistance, Shijiazhuang, 050011, China. .
Liu L; Department of Tumor Immunotherapy, The Fourth Hospital of Hebei Medical University and Hebei Provincial Tumor Hospital, Shijiazhuang, 050035, China. .; Cancer Research Institute of Hebei Province, Shijiazhuang, 050011, China. .; International Cooperation Laboratory of Stem Cell Research, Hebei Medical University, Shijiazhuang, 050011, China. .
Show more
Source:
Molecular cancer [Mol Cancer] 2024 Mar 08; Vol. 23 (1), pp. 47. Date of Electronic Publication: 2024 Mar 08.
Publication Type:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Cancer-Associated Fibroblasts*/metabolism
Humans ; Interleukin-6/genetics ; Interleukin-6/metabolism ; RNA, Circular/genetics ; RNA, Circular/metabolism ; In Situ Hybridization, Fluorescence ; Fibroblasts ; Cell Line, Tumor ; Cell Proliferation
Academic Journal
Title:
Simultaneous Expression of CD70 and POSTN in Cancer-Associated Fibroblasts Predicts Worse Survival of Colorectal Cancer Patients.
Authors:
Komura M; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Wang C; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Ito S; Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Kato S; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Ueki A; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Ebi M; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Ogasawara N; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Tsuzuki T; Surgical Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Kasai K; Department of Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Kasugai K; Division of Gastroenterology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.
Takiguchi S; Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Takahashi S; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
Inaguma S; Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.; Department of Pathology, Aichi Medical University School of Medicine, Nagakute 480-1195, Japan.; Department of Pathology, Nagoya City University East Medical Center, Nagoya 464-8547, Japan.
Show more
Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 22; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 22.
Publication Type:
Journal Article
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
Colorectal Neoplasms*/pathology
Humans ; Fibroblasts/metabolism ; Immunohistochemistry ; Cell Proliferation ; Cell Adhesion Molecules/metabolism ; CD27 Ligand/metabolism
Academic Journal
Title:
Dynamic phenotypic reprogramming and chemoresistance induced by lung fibroblasts in small cell lung cancer.
Authors:
Lu Y; Postdoctoral Research Workstation, Jilin Cancer Hospital, Changchun, China.
Li H; Medical Oncology Translational Research Lab, Jilin Cancer Hospital, No. 1066, Jinhu Road, High-tech District, Changchun, 130012, Jilin, China.
Zhao P; Medical Oncology Translational Research Lab, Jilin Cancer Hospital, No. 1066, Jinhu Road, High-tech District, Changchun, 130012, Jilin, China.
Tian L; Postdoctoral Research Workstation, Jilin Cancer Hospital, Changchun, China.
Liu Y; Medical Oncology Translational Research Lab, Jilin Cancer Hospital, No. 1066, Jinhu Road, High-tech District, Changchun, 130012, Jilin, China.
Sun X; Department of 1st Gynecologic Oncology Surgery, Jilin Cancer Hospital, Changchun, China.
Cheng Y; Medical Oncology Translational Research Lab, Jilin Cancer Hospital, No. 1066, Jinhu Road, High-tech District, Changchun, 130012, Jilin, China. .; Department of Medical Thoracic Oncology, Jilin Cancer Hospital, Changchun, China. .
Show more
Source:
Scientific reports [Sci Rep] 2024 Feb 05; Vol. 14 (1), pp. 2884. Date of Electronic Publication: 2024 Feb 05.
Publication Type:
Journal Article
MeSH Terms:
Small Cell Lung Carcinoma*/genetics
Small Cell Lung Carcinoma*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Carcinoma, Non-Small-Cell Lung*/genetics
Cancer-Associated Fibroblasts*/metabolism
Humans ; Drug Resistance, Neoplasm/genetics ; Fibroblasts/metabolism ; Phenotype ; Lung/metabolism ; Tumor Microenvironment
Academic Journal
Title:
Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancer.
Authors:
Chai C; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 10049, China.; Lars Bolund Institute of Regenerative Medicine Qingdao-Europe Advanced Institute for LifeScience, BGI Research, Qingdao, 266555, China.; BGI Research, Shenzhen, 518083, China.
Liang L; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 10049, China.; Lars Bolund Institute of Regenerative Medicine Qingdao-Europe Advanced Institute for LifeScience, BGI Research, Qingdao, 266555, China.; BGI Research, Shenzhen, 518083, China.
Mikkelsen NS; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Wang W; Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhao W; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 10049, China.; Lars Bolund Institute of Regenerative Medicine Qingdao-Europe Advanced Institute for LifeScience, BGI Research, Qingdao, 266555, China.
Sun C; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 10049, China.; Lars Bolund Institute of Regenerative Medicine Qingdao-Europe Advanced Institute for LifeScience, BGI Research, Qingdao, 266555, China.
Bak RO; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Li H; Lars Bolund Institute of Regenerative Medicine Qingdao-Europe Advanced Institute for LifeScience, BGI Research, Qingdao, 266555, China.; BGI Research, Shenzhen, 518083, China.
Lin L; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark.
Wang F; Lars Bolund Institute of Regenerative Medicine Qingdao-Europe Advanced Institute for LifeScience, BGI Research, Qingdao, 266555, China. .; BGI Research, Shenzhen, 518083, China. .; Department of Biomedicine, Aarhus University, Aarhus, Denmark. .
Luo Y; Lars Bolund Institute of Regenerative Medicine Qingdao-Europe Advanced Institute for LifeScience, BGI Research, Qingdao, 266555, China. .; BGI Research, Shenzhen, 518083, China. .; Department of Biomedicine, Aarhus University, Aarhus, Denmark. .; Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark. .
Show more
Source:
Communications biology [Commun Biol] 2024 Jan 26; Vol. 7 (1), pp. 131. Date of Electronic Publication: 2024 Jan 26.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
Ovarian Neoplasms*/pathology
Humans ; Female ; Cell Line, Tumor ; Single-Cell Gene Expression Analysis ; Fibroblasts/metabolism ; Tumor Microenvironment/genetics
Academic Journal
Title:
Cancer-Associated Fibroblast Heterogeneity in Malignancy with Focus on Oral Squamous Cell Carcinoma.
Authors:
Arebro J; Department of Interdisciplinary Oncology, British Columbia Cancer Research Centre, Vancouver, BC V5Z 1L3, Canada.; Division of ENT Diseases, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 14186 Stockholm, Sweden.; Department of ENT Diseases, Karolinska University Hospital, 14186 Stockholm, Sweden.
Lee CM; Department of Interdisciplinary Oncology, British Columbia Cancer Research Centre, Vancouver, BC V5Z 1L3, Canada.; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC V5Z 1L3, Canada.
Bennewith KL; Department of Interdisciplinary Oncology, British Columbia Cancer Research Centre, Vancouver, BC V5Z 1L3, Canada.; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC V5Z 1L3, Canada.; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z7, Canada.
Garnis C; Department of Interdisciplinary Oncology, British Columbia Cancer Research Centre, Vancouver, BC V5Z 1L3, Canada.; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC V5Z 1L3, Canada.; Division of Otolaryngology, Department of Surgery, University of British Columbia, Vancouver, BC V5Z 1M9, Canada.
Show more
Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 21; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 21.
Publication Type:
Journal Article; Review
MeSH Terms:
Carcinoma, Squamous Cell*/pathology
Mouth Neoplasms*/pathology
Cancer-Associated Fibroblasts*/metabolism
Head and Neck Neoplasms*/metabolism
Humans ; Squamous Cell Carcinoma of Head and Neck/metabolism ; Tumor Microenvironment ; Fibroblasts/metabolism
Academic Journal
Title:
Activation and Functions of Col6a1+ Fibroblasts in Colitis-Associated Cancer.
Authors:
Chalkidi N; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Centre (BSRC) 'Alexander Fleming', 16672 Vari, Greece.
Melissari MT; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Centre (BSRC) 'Alexander Fleming', 16672 Vari, Greece.
Henriques A; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Centre (BSRC) 'Alexander Fleming', 16672 Vari, Greece.
Stavropoulou A; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Centre (BSRC) 'Alexander Fleming', 16672 Vari, Greece.
Kollias G; Institute for Bioinnovation, Biomedical Sciences Research Centre (BSRC) 'Alexander Fleming', 16672 Vari, Greece.; Department of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Koliaraki V; Institute for Fundamental Biomedical Research, Biomedical Sciences Research Centre (BSRC) 'Alexander Fleming', 16672 Vari, Greece.
Show more
Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 21; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 21.
Publication Type:
Journal Article
MeSH Terms:
Colitis-Associated Neoplasms*
Cancer-Associated Fibroblasts*
Adenoma*
Humans ; Fibroblasts ; Carcinogenesis ; Tumor Necrosis Factor-alpha ; Collagen Type VI
Academic Journal
Title:
Transcription factors in fibroblast plasticity and CAF heterogeneity.
Authors:
Melchionna R; Tumor Immunology and Immunotherapy Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy. .
Trono P; Tumor Immunology and Immunotherapy Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy.; Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Rome, Italy.
Di Carlo A; Tumor Immunology and Immunotherapy Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy.
Di Modugno F; Tumor Immunology and Immunotherapy Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy.
Nisticò P; Tumor Immunology and Immunotherapy Unit, IRCCS-Regina Elena National Cancer Institute, Rome, Italy.
Show more
Source:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Dec 20; Vol. 42 (1), pp. 347. Date of Electronic Publication: 2023 Dec 20.
Publication Type:
Journal Article; Review
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
Neoplasms*/pathology
Humans ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Fibroblasts/metabolism ; Phenotype ; Tumor Microenvironment/genetics
Academic Journal
Title:
Cancer-associated fibroblasts induce sorafenib resistance of hepatocellular carcinoma cells through CXCL12/FOLR1.
Authors:
Zhao J; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China. .
Lin E; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Bai Z; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Jia Y; Department of Urology Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Wang B; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Dai Y; Department of Anesthesiology, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Zhuo W; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Zeng G; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Liu X; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Cai C; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China.
Li P; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China. .
Zou B; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China. .
Li J; Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, 519000, Guangdong, China. .
Show more
Source:
BMC cancer [BMC Cancer] 2023 Dec 06; Vol. 23 (1), pp. 1198. Date of Electronic Publication: 2023 Dec 06.
Publication Type:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Liver Neoplasms*/metabolism
Cancer-Associated Fibroblasts*/metabolism
Humans ; Sorafenib/pharmacology ; Sorafenib/therapeutic use ; Cell Line, Tumor ; Fibroblasts/metabolism ; Drug Resistance, Neoplasm ; Cell Proliferation ; Folate Receptor 1/metabolism ; Folate Receptor 1/therapeutic use ; Chemokine CXCL12/genetics ; Chemokine CXCL12/metabolism
Academic Journal
Title:
Cancer-Associated Fibroblasts in Gastrointestinal Cancers: Unveiling Their Dynamic Roles in the Tumor Microenvironment.
Authors:
Al-Bzour NN; Department of Medicine, Division of Hematology & Oncology, University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA 15232, USA.
Al-Bzour AN; Department of Medicine, Division of Hematology & Oncology, University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA 15232, USA.
Ababneh OE; Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Al-Jezawi MM; Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Saeed A; Department of Pathology and Laboratory Medicine, University of Vermont Medical Center, Burlington, VT 05401, USA.
Saeed A; Department of Medicine, Division of Hematology & Oncology, University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA 15232, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.
Show more
Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 19; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 19.
Publication Type:
Journal Article; Review
MeSH Terms:
Cancer-Associated Fibroblasts*/pathology
Gastrointestinal Neoplasms*/pathology
Humans ; Tumor Microenvironment ; Endothelial Cells ; Fibroblasts/pathology
Academic Journal
Title:
Crosstalk and plasticity driving between cancer-associated fibroblasts and tumor microenvironment: significance of breast cancer metastasis.
Authors:
Zhang W; State Key Laboratory of Quality Research in Chinese Medicine, and Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, China.; College of Traditional Chinese Medicine, Weifang Medical University, Weifang, 261000, China.; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Wang J; State Key Laboratory of Quality Research in Chinese Medicine, and Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, China.; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Liu C; College of Traditional Chinese Medicine, Weifang Medical University, Weifang, 261000, China.
Li Y; State Key Laboratory of Quality Research in Chinese Medicine, and Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, China.
Sun C; State Key Laboratory of Quality Research in Chinese Medicine, and Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, China. .; College of Traditional Chinese Medicine, Weifang Medical University, Weifang, 261000, China. .; Department of Oncology, Weifang Traditional Chinese Hospital, Weifang, 261000, China. .
Wu J; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China. .
Wu Q; State Key Laboratory of Quality Research in Chinese Medicine, and Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, 999078, Macau, China. .
Show more
Source:
Journal of translational medicine [J Transl Med] 2023 Nov 17; Vol. 21 (1), pp. 827. Date of Electronic Publication: 2023 Nov 17.
Publication Type:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/pathology
Cancer-Associated Fibroblasts*/pathology
Humans ; Female ; Fibroblasts/pathology ; Breast/pathology ; Tumor Microenvironment ; Melanoma, Cutaneous Malignant
Academic Journal
Title:
MYL9 expressed in cancer-associated fibroblasts regulate the immune microenvironment of colorectal cancer and promotes tumor progression in an autocrine manner.
Authors:
Deng S; Center for Liver Transplantation, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Cheng D; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Wang J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Gu J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Xue Y; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Jiang Z; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Qin L; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Mao F; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Cao Y; Department of Digestive Surgical Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
Cai K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
Show more
Source:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Nov 06; Vol. 42 (1), pp. 294. Date of Electronic Publication: 2023 Nov 06.
Publication Type:
Journal Article
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
Colorectal Neoplasms*/pathology
Myosin Light Chains*/genetics
Animals ; Cell Line, Tumor ; Cell Proliferation ; Fibroblasts/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Transcription Factors/metabolism ; Transforming Growth Factor beta1/metabolism ; Tumor Microenvironment ; Humans
Academic Journal
Title:
Pan-cancer spatially resolved single-cell analysis reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment.
Authors:
Ma C; Department of Human Microbiome and Periodontology and Implantology and Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University and Shandong Key Laboratory of Oral Tissue Regeneration and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration and Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, China.
Yang C; Department of Oral and Maxillofacial Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China.; Institute of Stomatology, Shandong University, Jinan, Shandong, China.
Peng A; Department of Human Microbiome and Periodontology and Implantology and Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University and Shandong Key Laboratory of Oral Tissue Regeneration and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration and Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, China.
Sun T; Department of Human Microbiome and Periodontology and Implantology and Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University and Shandong Key Laboratory of Oral Tissue Regeneration and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration and Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, China.
Ji X; Department of Stomatology, Central Hospital Affiliated to Shandong First Medical University, No.105 Jiefang Road, Jinan, Shandong, China.
Mi J; Department of Human Microbiome and Periodontology and Implantology and Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University and Shandong Key Laboratory of Oral Tissue Regeneration and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration and Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, China.
Wei L; Department of Human Microbiome and Periodontology and Implantology and Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University and Shandong Key Laboratory of Oral Tissue Regeneration and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration and Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, China.
Shen S; Department of Human Microbiome and Periodontology and Implantology and Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University and Shandong Key Laboratory of Oral Tissue Regeneration and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration and Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, China.
Feng Q; Department of Human Microbiome and Periodontology and Implantology and Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University and Shandong Key Laboratory of Oral Tissue Regeneration and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration and Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, China. .; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, China. .
Show more
Source:
Molecular cancer [Mol Cancer] 2023 Oct 13; Vol. 22 (1), pp. 170. Date of Electronic Publication: 2023 Oct 13.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cancer-Associated Fibroblasts*/metabolism
Carcinoma*/metabolism
Humans ; Tumor Microenvironment ; Epithelial-Mesenchymal Transition/genetics ; Single-Cell Analysis ; Fibroblasts
Academic Journal
Title:
Neutralizing tumor-related inflammation and reprogramming of cancer-associated fibroblasts by Curcumin in breast cancer therapy.
Authors:
Jalilian E; Department of Medical Immunology, School of Medicine, Kerman University of Medical Sciences, Pajoohesh Sq, Kerman, Iran.
Abolhasani-Zadeh F; Department of Surgery, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Afgar A; Departmeny of Parasitology and Mycology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Samoudi A; Department of Medical Immunology, School of Medicine, Kerman University of Medical Sciences, Pajoohesh Sq, Kerman, Iran.
Zeinalynezhad H; Department of Surgery, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Langroudi L; Department of Medical Immunology, School of Medicine, Kerman University of Medical Sciences, Pajoohesh Sq, Kerman, Iran. .
Show more
Source:
Scientific reports [Sci Rep] 2023 Nov 26; Vol. 13 (1), pp. 20770. Date of Electronic Publication: 2023 Nov 26.
Publication Type:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Cancer-Associated Fibroblasts*/metabolism
Curcumin*/pharmacology
Curcumin*/therapeutic use
Curcumin*/metabolism
Humans ; Female ; Cyclooxygenase 2/metabolism ; Dinoprostone/metabolism ; Fibroblasts/metabolism ; Inflammation/pathology ; Cell Line, Tumor ; Tumor Microenvironment
Academic Journal
Title:
Define cancer-associated fibroblasts (CAFs) in the tumor microenvironment: new opportunities in cancer immunotherapy and advances in clinical trials.
Authors:
Zhang H; Department of Neurosurgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Yue X; Department of Neurosurgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.; Department of Urology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Chen Z; Department of Neurosurgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Liu C; Department of Neurosurgery, Central Hospital of Zhuzhou, Zhuzhou, China.
Wu W; Department of Oncology, Xiangya Hospital, Central South University, Changsha, China.
Zhang N; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Liu Z; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yang L; Department of Laboratory Medicine, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Jiang Q; Department of Urology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Cheng Q; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China. .; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China. .
Luo P; Department of Neurosurgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China. .; Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China. .
Liu G; Department of Neurosurgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China. .
Show more
Source:
Molecular cancer [Mol Cancer] 2023 Oct 02; Vol. 22 (1), pp. 159. Date of Electronic Publication: 2023 Oct 02.
Publication Type:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Cancer-Associated Fibroblasts*/pathology
Neoplasms*/therapy
Neoplasms*/pathology
Humans ; Disease Progression ; Immunotherapy ; Tumor Microenvironment ; Fibroblasts
Academic Journal

We use cookies to help identify your computer so we can tailor your user experience, track shopping basket contents and remember where you are in the order process.