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Tytuł :
Two new polyoxygenated flavonoids from Blumea eriantha DC, methanol extract and their anti-proliferative activity.
Autorzy :
Tambewagh UU; R & D Centre in Pharmaceutical Sciences and Applied Chemistry, PCP Campus, Bharati Vidyapeeth (Deemed to Be University), Erandwane, Pune, India.
Javir GR; Department of Technology, Savitribai Phule Pune University, Pune, India.; Department of Biotechnology, SCOE, Affiliated to Savitribai Phule Pune University, Pune, India.
Joshi KS; Department of Biotechnology, SCOE, Affiliated to Savitribai Phule Pune University, Pune, India.
Rojatkar SR; R & D Centre in Pharmaceutical Sciences and Applied Chemistry, PCP Campus, Bharati Vidyapeeth (Deemed to Be University), Erandwane, Pune, India.
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Źródło :
Natural product research [Nat Prod Res] 2021 Sep; Vol. 35 (17), pp. 2815-2822. Date of Electronic Publication: 2019 Oct 03.
Typ publikacji :
Journal Article
MeSH Terms :
Asteraceae*/chemistry
Flavonoids*/isolation & purification
Flavonoids*/pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Antineoplastic Agents, Phytogenic/isolation & purification ; Cell Line, Tumor ; Humans ; Methanol ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Plant Extracts/pharmacology
Czasopismo naukowe
Tytuł :
Anastatin Derivatives Alleviate Myocardial Ischemia-Reperfusion Injury via Antioxidative Properties.
Autorzy :
Fu Y; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Bioengineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Zhao C; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Bioengineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Saxu R; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Bioengineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Yao C; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Bioengineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Zhao L; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Bioengineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Zheng W; Medical College, Yanbian University, No.977 Gongyuan Road, Yanji 133002, China.
Yu P; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Bioengineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Teng Y; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Bioengineering, Tianjin University of Science and Technology, Tianjin 300457, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 06; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*chemistry
Antioxidants/*pharmacology
Flavonoids/*chemistry
Flavonoids/*pharmacology
Myocardial Reperfusion Injury/*drug therapy
Animals ; Antioxidants/therapeutic use ; Apoptosis/drug effects ; Cell Survival/drug effects ; Flavonoids/therapeutic use ; Glutathione/metabolism ; Male ; Malondialdehyde/metabolism ; Myocardial Reperfusion Injury/metabolism ; Myocardial Reperfusion Injury/pathology ; Oxidative Stress/drug effects ; Rats
Czasopismo naukowe
Tytuł :
Prenylated Flavonoids and C-15 Isoprenoid Analogues with Antibacterial Properties from the Whole Plant of Imperata cylindrica (L.) Raeusch (Gramineae).
Autorzy :
Nago RDT; Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.
Nayim P; Department of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.
Mbaveng AT; Department of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.
Mpetga JDS; Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.
Bitchagno GTM; Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, D-33501 Bielefeld, Germany.
Garandi B; Department of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.
Tane P; Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.
Lenta BN; Department of Chemistry, Higher Teacher Training College, University of Yaounde I, P.O. Box 47 Yaounde, Cameroon.
Sewald N; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, D-33501 Bielefeld, Germany.
Tene M; Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.
Kuete V; Department of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.
Ngouela AS; Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67 Dschang, Cameroon.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 04; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 04.
Typ publikacji :
Journal Article
MeSH Terms :
Prenylation*
Anti-Bacterial Agents/*pharmacology
Flavonoids/*pharmacology
Poaceae/*chemistry
Terpenes/*pharmacology
Carbon-13 Magnetic Resonance Spectroscopy ; Flavonoids/chemistry ; Flavonoids/isolation & purification ; Microbial Sensitivity Tests ; Proton Magnetic Resonance Spectroscopy ; Terpenes/chemistry ; Terpenes/isolation & purification
Czasopismo naukowe
Tytuł :
Current methodologies to refine bioavailability, delivery, and therapeutic efficacy of plant flavonoids in cancer treatment.
Autorzy :
Vazhappilly CG; Department of Biotechnology, American University of Ras Al Khaimah, Ras Al Khaimah, UAE. Electronic address: .
Amararathna M; Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia, Canada.
Cyril AC; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE.
Linger R; Department of Pharmaceutical and Administrative Sciences, University of Charleston, Charleston, West Virginia, USA.
Matar R; Department of Biotechnology, American University of Ras Al Khaimah, Ras Al Khaimah, UAE.
Merheb M; Department of Biotechnology, American University of Ras Al Khaimah, Ras Al Khaimah, UAE.
Ramadan WS; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, UAE; College of Medicine, University of Sharjah, Sharjah, UAE.
Radhakrishnan R; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE.
Rupasinghe HPV; Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia, Canada; Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
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Źródło :
The Journal of nutritional biochemistry [J Nutr Biochem] 2021 Aug; Vol. 94, pp. 108623. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Flavonoids/*pharmacology
Neoplasms/*drug therapy
Antineoplastic Agents, Phytogenic/adverse effects ; Antineoplastic Agents, Phytogenic/chemistry ; Biological Availability ; Diet ; Drug Delivery Systems ; Flavonoids/adverse effects ; Flavonoids/chemistry ; Flavonoids/pharmacokinetics ; Humans
Czasopismo naukowe
Tytuł :
Systems biology analysis of the effect and mechanism of total flavonoids of Astragali Radix against cyclophosphamide-induced leucopenia in mice.
Autorzy :
Qu T; School of Pharmaceutical Science of Shanxi Medical University, No.56, Xinjian south Road, Taiyuan 030001, Shanxi, People's Republic of China; Modern Research Center for Traditional Chinese Medicine of Shanxi University, No.92, Wucheng Road, Taiyuan 030006, Shanxi, People's Republic of China.
Gao Y; Modern Research Center for Traditional Chinese Medicine of Shanxi University, No.92, Wucheng Road, Taiyuan 030006, Shanxi, People's Republic of China.
Li A; Modern Research Center for Traditional Chinese Medicine of Shanxi University, No.92, Wucheng Road, Taiyuan 030006, Shanxi, People's Republic of China.
Li Z; Modern Research Center for Traditional Chinese Medicine of Shanxi University, No.92, Wucheng Road, Taiyuan 030006, Shanxi, People's Republic of China. Electronic address: .
Qin X; Modern Research Center for Traditional Chinese Medicine of Shanxi University, No.92, Wucheng Road, Taiyuan 030006, Shanxi, People's Republic of China. Electronic address: .
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Źródło :
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2021 Oct 25; Vol. 205, pp. 114357. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/pharmacology
Flavonoids*/pharmacology
Animals ; Cyclophosphamide/toxicity ; Mice ; Phosphatidylinositol 3-Kinases ; Systems Biology
Czasopismo naukowe
Tytuł :
Comparative analysis of excretion of six major compounds of Polygonum orientale L. extract in urine, feces and bile under physiological and myocardial ischemia conditions in rats using UPLC-MS/MS.
Autorzy :
Lu Y; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China.
Li N; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China.; School of Pharmacy, Guizhou Medical University, Guiyang, China.
Zhu X; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China.; School of Pharmacy, Guizhou Medical University, Guiyang, China.
Pan J; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, China.
Wang Y; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China.
Lan Y; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, China.
Li Y; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, China.
Wang A; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, China.
Sun J; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, China.
Liu C; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, China.
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Źródło :
Biomedical chromatography : BMC [Biomed Chromatogr] 2021 Oct; Vol. 35 (10), pp. e5174. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Flavonoids*/analysis
Flavonoids*/chemistry
Flavonoids*/pharmacokinetics
Plant Extracts*/administration & dosage
Plant Extracts*/pharmacokinetics
Polygonum*
Chromatography, High Pressure Liquid/*methods
Myocardial Ischemia/*metabolism
Animals ; Bile/chemistry ; Feces/chemistry ; Limit of Detection ; Linear Models ; Male ; Rats ; Rats, Sprague-Dawley ; Reproducibility of Results ; Tandem Mass Spectrometry/methods
Czasopismo naukowe
Tytuł :
Preparative isolation of apple flavan-3-ols monomers and oligomers using pH-zone-refining centrifugal partition chromatography combined with reversed-phase liquid chromatography.
Autorzy :
Guilois-Dubois S; INRAE UR BIA-Polyphenols, Reactivity, Processes, Le Rheu F-35653, France; UMT ACTIA Nova2Cidre, Le Rheu F-35653, France.
Guyot S; INRAE UR BIA-Polyphenols, Reactivity, Processes, Le Rheu F-35653, France; UMT ACTIA Nova2Cidre, Le Rheu F-35653, France. Electronic address: .
Poupard P; IFPC (French Institute for Cider Production), Le Rheu F-35653, France; UMT ACTIA Nova2Cidre, Le Rheu F-35653, France.
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2021 Sep 13; Vol. 1653, pp. 462382. Date of Electronic Publication: 2021 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography, Liquid*
Chromatography, Reverse-Phase*
Flavonoids*/chemistry
Flavonoids*/isolation & purification
Malus*/chemistry
Hydrogen-Ion Concentration
Czasopismo naukowe
Tytuł :
Wound healing properties of flavonoids: A systematic review highlighting the mechanisms of action.
Autorzy :
Carvalho MTB; Laboratory of Neuroscience and Pharmacological Assays (LANEF), Department of Physiology, Federal University of Sergipe, Marechal Rondon Avenue, S/N, Rosa Elza, CEP: 49.000-100, São Cristóvão, SE, Brazil; Health Sciences Graduate Program (PPGCS), Federal University of Sergipe, São Cristóvão, SE, Brazil.
Araújo-Filho HG; Laboratory of Neuroscience and Pharmacological Assays (LANEF), Department of Physiology, Federal University of Sergipe, Marechal Rondon Avenue, S/N, Rosa Elza, CEP: 49.000-100, São Cristóvão, SE, Brazil.
Barreto AS; Health Sciences Graduate Program (PPGCS), Federal University of Sergipe, São Cristóvão, SE, Brazil; Laboratory Pharmacology Cardiovascular (LAFAC), Department of Physiology, Federal University of Sergipe, São Cristóvão, SE, Brazil.
Quintans-Júnior LJ; Laboratory of Neuroscience and Pharmacological Assays (LANEF), Department of Physiology, Federal University of Sergipe, Marechal Rondon Avenue, S/N, Rosa Elza, CEP: 49.000-100, São Cristóvão, SE, Brazil; Health Sciences Graduate Program (PPGCS), Federal University of Sergipe, São Cristóvão, SE, Brazil.
Quintans JSS; Laboratory of Neuroscience and Pharmacological Assays (LANEF), Department of Physiology, Federal University of Sergipe, Marechal Rondon Avenue, S/N, Rosa Elza, CEP: 49.000-100, São Cristóvão, SE, Brazil; Health Sciences Graduate Program (PPGCS), Federal University of Sergipe, São Cristóvão, SE, Brazil.
Barreto RSS; Laboratory of Neuroscience and Pharmacological Assays (LANEF), Department of Physiology, Federal University of Sergipe, Marechal Rondon Avenue, S/N, Rosa Elza, CEP: 49.000-100, São Cristóvão, SE, Brazil; Health Sciences Graduate Program (PPGCS), Federal University of Sergipe, São Cristóvão, SE, Brazil. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Sep; Vol. 90, pp. 153636. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Flavonoids*/pharmacology
Wound Healing*
Animals ; Cytokines ; Endothelial Cells ; Fibroblasts ; Macrophages ; Signal Transduction
Czasopismo naukowe
Tytuł :
Anthelmintic flavonoids and other compounds from Combretum glutinosum Perr. ex DC (Combretaceae) leaves.
Autorzy :
Toklo PM; Laboratoire de Pharmacognosie et des Huiles Essentielles, Facultés des Sciences et Techniques, Université d'Abomey Calavi, 01 BP: 918 ISBA Cotonou, Benin.
Yayi Ladekan E; Laboratoire de Pharmacognosie et des Huiles Essentielles, Facultés des Sciences et Techniques, Université d'Abomey Calavi, 01 BP: 918 ISBA Cotonou, Benin.
Linden A; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Hounzangbe-Adote S; Laboratoire d'Ethnopharmacologie et de Santé Animale, Faculté des Sciences Agronomiques, Université d'Abomey Calavi, 01 BP: 526 Cotonou, Benin.
Kouam SF; Department of Chemistry, Higher Teacher Training College, University of Yaounde I, PO Box 47, 4124 Yaounde, Cameroon.
Gbenou JD; Laboratoire de Pharmacognosie et des Huiles Essentielles, Facultés des Sciences et Techniques, Université d'Abomey Calavi, 01 BP: 918 ISBA Cotonou, Benin.
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Źródło :
Acta crystallographica. Section C, Structural chemistry [Acta Crystallogr C Struct Chem] 2021 Sep 01; Vol. 77 (Pt 9), pp. 505-512. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anthelmintics/*pharmacology
Anti-Infective Agents/*pharmacology
Combretaceae/*drug effects
Combretum/*chemistry
Flavones/*pharmacology
Flavonoids/*chemistry
Haemonchus/*drug effects
Larva/*drug effects
Plant Leaves/*drug effects
Animals ; Anthelmintics/chemistry ; Anthelmintics/therapeutic use ; Anti-Infective Agents/chemistry ; Crystallography, X-Ray ; Flavones/chemistry ; Flavonoids/pharmacology ; Haemonchus/growth & development ; Hydrogen Bonding ; Plant Leaves/chemistry
Czasopismo naukowe
Tytuł :
The study of citrus-derived flavonoids as effective bitter taste inhibitors.
Autorzy :
Huang J; School of Chemical Engineering and Light Industry, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Lu YJ; School of Chemical Engineering and Light Industry, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.; Goldenpomelo Biotechnology Co. Ltd, Meizhou, China.; Zhongke Institute (Meizhou) of High-Value Utilization of Green Plants, Meizhou, China.
Guo C; School of Chemical Engineering and Light Industry, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Zuo S; School of Chemical Engineering and Light Industry, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
Zhou JL; Goldenpomelo Biotechnology Co. Ltd, Meizhou, China.; Zhongke Institute (Meizhou) of High-Value Utilization of Green Plants, Meizhou, China.
Wong WL; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.; International Healthcare Innovation Institute (Jiangmen), Jiangmen, China.
Huang B; School of Chemical Engineering and Light Industry, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.
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Źródło :
Journal of the science of food and agriculture [J Sci Food Agric] 2021 Sep; Vol. 101 (12), pp. 5163-5171. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Journal Article
MeSH Terms :
Citrus/*chemistry
Flavonoids/*chemistry
Flavoring Agents/*chemistry
Plant Extracts/*chemistry
Electronic Nose ; Flavonoids/isolation & purification ; Flavoring Agents/isolation & purification ; Humans ; Plant Extracts/isolation & purification ; Taste ; Wine/analysis
Czasopismo naukowe
Tytuł :
New perspectives on natural flavonoids on COVID-19-induced lung injuries.
Autorzy :
Santana FPR; Department of Bioscience, Federal University of São Paulo, Santos, São Paulo, Brazil.; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, São Paulo, Brazil.
Thevenard F; Center of Natural Sciences and Humanities, Federal University of ABC, São Paulo, São Paulo, Brazil.
Gomes KS; Center of Natural Sciences and Humanities, Federal University of ABC, São Paulo, São Paulo, Brazil.
Taguchi L; Department of Bioscience, Federal University of São Paulo, Santos, São Paulo, Brazil.
Câmara NOS; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, São Paulo, Brazil.
Stilhano RS; Department of Physiological Sciences, Santa Casa de São Paulo School of Medical Sciences, São Paulo, São Paulo, Brazil.
Ureshino RP; Department of Biological Science, Federal University of São Paulo, Diadema, São Paulo, Brazil.
Prado CM; Department of Bioscience, Federal University of São Paulo, Santos, São Paulo, Brazil.
Lago JHG; Center of Natural Sciences and Humanities, Federal University of ABC, São Paulo, São Paulo, Brazil.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Sep; Vol. 35 (9), pp. 4988-5006. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19*/complications
Flavonoids*/pharmacology
Lung Injury*/drug therapy
Lung Injury*/virology
Humans ; Pandemics
Czasopismo naukowe
Tytuł :
Chemoprevention assessment, genotoxicity and cytotoxicity of flavonoids from Inga laurina leaves (FABACEAE).
Autorzy :
Sanzovo TOR; School of Pharmaceutical Sciences, Department of Clinical Analysis, São Paulo State University UNESP, Araraquara, SP, Brazil.
Lima NM; Institute of Chemistry, Nucleus Bioassays Biosynthesis & Ecophysiology of Natural Products, São Paulo State University UNESP, Araraquara, SP, Brazil.
Marqui SR; Institute of Chemistry, Nucleus Bioassays Biosynthesis & Ecophysiology of Natural Products, São Paulo State University UNESP, Araraquara, SP, Brazil.
Andrade TJAS; NIAC-Nucleus of Research Applied to Sciences-IFMA-Federal Institute of Education, Science and Technology of Maranhão.
Navegante G; School of Pharmaceutical Sciences, Department of Clinical Analysis, São Paulo State University UNESP, Araraquara, SP, Brazil.
Serafim RB; School of Pharmaceutical Sciences, Department of Clinical Analysis, São Paulo State University UNESP, Araraquara, SP, Brazil.
Sorbo JM; School of Pharmaceutical Sciences, Department of Clinical Analysis, São Paulo State University UNESP, Araraquara, SP, Brazil.
Valente V; School of Pharmaceutical Sciences, Department of Clinical Analysis, São Paulo State University UNESP, Araraquara, SP, Brazil.
Silva DHS; Institute of Chemistry, Nucleus Bioassays Biosynthesis & Ecophysiology of Natural Products, São Paulo State University UNESP, Araraquara, SP, Brazil.
Soares CP; School of Pharmaceutical Sciences, Department of Clinical Analysis, São Paulo State University UNESP, Araraquara, SP, Brazil.
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Źródło :
Natural product research [Nat Prod Res] 2021 Sep; Vol. 35 (18), pp. 3089-3094. Date of Electronic Publication: 2019 Nov 07.
Typ publikacji :
Journal Article
MeSH Terms :
Chemoprevention*
Fabaceae*/chemistry
Flavonoids/*pharmacology
Animals ; Comet Assay ; DNA Damage ; Flavonoids/isolation & purification ; Hep G2 Cells ; Humans ; Mice ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Plant Extracts/pharmacology ; Plant Leaves/chemistry
Czasopismo naukowe
Tytuł :
Construction of a nanotheranostic system ‑oxygen consumption and hypoxia sensitive chemotherapeutic drug.
Autorzy :
Wang X; Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, College of Chemistry & Chemical Engineering, Harbin Normal University, Harbin 150025, China.
Wang Z; Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, College of Chemistry & Chemical Engineering, Harbin Normal University, Harbin 150025, China. Electronic address: .
Ma W; Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, College of Chemistry & Chemical Engineering, Harbin Normal University, Harbin 150025, China.
Wu X; Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, College of Chemistry & Chemical Engineering, Harbin Normal University, Harbin 150025, China.
Fang W; Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, College of Chemistry & Chemical Engineering, Harbin Normal University, Harbin 150025, China.
Guo C; Key Laboratory of Molecular Cytogenetics and Genetic Breeding of Heilongjiang Province, College of Life Science and Technology, Harbin Normal University, Harbin 150025, China. Electronic address: .
Jin Y; Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, College of Chemistry & Chemical Engineering, Harbin Normal University, Harbin 150025, China; Key Laboratory of Molecular Cytogenetics and Genetic Breeding of Heilongjiang Province, College of Life Science and Technology, Harbin Normal University, Harbin 150025, China. Electronic address: .
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Źródło :
Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2021 Sep; Vol. 222, pp. 112274. Date of Electronic Publication: 2021 Jul 25.
Typ publikacji :
Journal Article
MeSH Terms :
Theranostic Nanomedicine*
Chlorophyll/*analogs & derivatives
Flavonoids/*chemistry
Metal-Organic Frameworks/*chemistry
Nanocomposites/*chemistry
Photochemotherapy/*methods
Animals ; Biocompatible Materials/chemistry ; Biocompatible Materials/pharmacology ; Biocompatible Materials/therapeutic use ; Cell Line, Tumor ; Cell Survival/drug effects ; Chlorophyll/chemistry ; Chlorophyll/metabolism ; Chlorophyll/therapeutic use ; Drug Liberation ; Female ; Flavonoids/metabolism ; Flavonoids/therapeutic use ; Humans ; Mice ; Mice, Inbred BALB C ; Nanocomposites/therapeutic use ; Nanocomposites/toxicity ; Neoplasms/drug therapy ; Neoplasms/pathology ; Polyethylene Glycols/chemistry ; Singlet Oxygen/metabolism ; Tumor Microenvironment ; Zirconium/chemistry
Czasopismo naukowe
Tytuł :
Flavonoids from Polyalthia longifolia prevents advanced glycation end products formation and protein oxidation aligned with fructose-induced protein glycation.
Autorzy :
Rai AK; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, India.
Singh SP; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, India.
Pandey AR; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, India.
Ansari A; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, India.
Ahmad S; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, India.; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.
Sashidhara KV; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, India.
Tamrakar AK; Biochemistry Division, CSIR-Central Drug Research Institute, Lucknow, India.; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India.
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Źródło :
Natural product research [Nat Prod Res] 2021 Sep; Vol. 35 (17), pp. 2921-2925. Date of Electronic Publication: 2019 Oct 04.
Typ publikacji :
Journal Article
MeSH Terms :
Flavonoids*/isolation & purification
Flavonoids*/pharmacology
Glycation End Products, Advanced*
Polyalthia*/chemistry
Fructose ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Plant Leaves/chemistry ; Serum Albumin, Bovine
Czasopismo naukowe
Tytuł :
Trifluoromethylated Flavonoid-Based Isoxazoles as Antidiabetic and Anti-Obesity Agents: Synthesis, In Vitro α -Amylase Inhibitory Activity, Molecular Docking and Structure-Activity Relationship Analysis.
Autorzy :
Algethami FK; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia.
Saidi I; Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11ES39), Medicinal Chemistry and Natural Products Team, Faculty of Science of Monastir, University of Monastir, Avenue of Environment, Monastir 5019, Tunisia.
Abdelhamid HN; Department of Chemistry, Advanced Multifunctional Materials Laboratory, Faculty of Science, Assiut University, Assiut 71575, Egypt.
Elamin MR; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia.
Abdulkhair BY; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia.
Chrouda A; Department of Chemistry, College of Science Al-Zulfi, Majmaah University, Al-Majmaah 11952, Saudi Arabia.
Ben Jannet H; Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11ES39), Medicinal Chemistry and Natural Products Team, Faculty of Science of Monastir, University of Monastir, Avenue of Environment, Monastir 5019, Tunisia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 27; Vol. 26 (17). Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Obesity Agents/*pharmacology
Diabetes Mellitus/*drug therapy
Flavonoids/*pharmacology
Hypoglycemic Agents/*pharmacology
Isoxazoles/*pharmacology
alpha-Amylases/*antagonists & inhibitors
Anti-Obesity Agents/chemistry ; Diabetes Mellitus/metabolism ; Flavonoids/chemistry ; Glycoside Hydrolase Inhibitors/chemistry ; Glycoside Hydrolase Inhibitors/pharmacology ; Humans ; Hypoglycemic Agents/chemistry ; Isoxazoles/chemistry ; Molecular Docking Simulation ; Structure-Activity Relationship ; alpha-Glucosidases/metabolism
Czasopismo naukowe
Tytuł :
Increased habitual flavonoid intake predicts attenuation of cognitive ageing in twins.
Autorzy :
Jennings A; Institute for Global Food Security, Queen's University Belfast, Belfast, Northern Ireland.
Steves CJ; Department of Twin Research & Genetic Epidemiology, King's College London, St Thomas' Campus, London, UK.
Macgregor A; Norwich Medical School, University of East Anglia, Norwich, UK.
Spector T; Department of Twin Research & Genetic Epidemiology, King's College London, St Thomas' Campus, London, UK.
Cassidy A; Institute for Global Food Security, Queen's University Belfast, Belfast, Northern Ireland. .
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Źródło :
BMC medicine [BMC Med] 2021 Aug 23; Vol. 19 (1), pp. 185. Date of Electronic Publication: 2021 Aug 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anthocyanins*
Flavonoids*
Aging ; Child ; Cognition ; Cross-Sectional Studies ; Diet ; Female ; Humans
Czasopismo naukowe
Tytuł :
Anticoronavirus and Immunomodulatory Phenolic Compounds: Opportunities and Pharmacotherapeutic Perspectives.
Autorzy :
Dejani NN; Department of Physiology and Pathology, Federal University of Paraíba, João Pessoa 58051-900, Brazil.
Elshabrawy HA; Department of Molecular and Cellular Biology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304, USA.
Bezerra Filho CDSM; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa 58051-900, Brazil.; Postgraduate Program in Bioactive Natural and Synthetic Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.
de Sousa DP; Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa 58051-900, Brazil.; Postgraduate Program in Bioactive Natural and Synthetic Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.
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Źródło :
Biomolecules [Biomolecules] 2021 Aug 23; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antiviral Agents/*therapeutic use
COVID-19/*drug therapy
Flavonoids/*therapeutic use
Immunologic Factors/*therapeutic use
Phytochemicals/*therapeutic use
Protease Inhibitors/*therapeutic use
Animals ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Coronavirus/drug effects ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Humans ; Immunologic Factors/chemistry ; Immunologic Factors/pharmacology ; Phytochemicals/chemistry ; Phytochemicals/pharmacology ; Protease Inhibitors/chemistry ; Protease Inhibitors/pharmacology
Czasopismo naukowe
Tytuł :
Protective Effects of Flavonoids Against Mitochondriopathies and Associated Pathologies: Focus on the Predictive Approach and Personalized Prevention.
Autorzy :
Koklesova L; Clinic of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Liskova A; Clinic of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Samec M; Clinic of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Zhai K; Department of Physiology and Biophysics, Weill Cornell Medicine in Qatar, Education City, Qatar Foundation, Doha 24144, Qatar.
Al-Ishaq RK; Department of Physiology and Biophysics, Weill Cornell Medicine in Qatar, Education City, Qatar Foundation, Doha 24144, Qatar.
Bugos O; Lambda Life JSC, 851 01 Bratislava, Slovakia.
Šudomová M; Museum of Literature in Moravia, Klášter 1, 664 61 Rajhrad, Czech Republic.
Biringer K; Clinic of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Pec M; Department of Medical Biology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Adamkov M; Department of Histology and Embryology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Hassan STS; Department of Applied Ecology, Faculty of Environmental Sciences, Czech University of Life Sciences Prague, Kamýcká 129, 165 00 Prague, Czech Republic.
Saso L; Department of Physiology and Pharmacology 'Vittorio Erspamer', Faculty of Pharmacy and Medicine, Sapienza University, 00185 Rome, Italy.
Giordano FA; Department of Radiation Oncology, University Hospital Bonn, Rheinische Friedrich-Wilhelms-Universität Bonn, 53127 Bonn, Germany.
Büsselberg D; Department of Physiology and Biophysics, Weill Cornell Medicine in Qatar, Education City, Qatar Foundation, Doha 24144, Qatar.
Kubatka P; Department of Medical Biology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.; European Association for Predictive, Preventive and Personalised Medicine, EPMA, 1150 Brussels, Belgium.
Golubnitschaja O; European Association for Predictive, Preventive and Personalised Medicine, EPMA, 1150 Brussels, Belgium.; Predictive, Preventive, Personalised (3P) Medicine, Department of Radiation Oncology, University Hospital Bonn, Rheinische Friedrich-Wilhelms-Universität Bonn, 53127 Bonn, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 11; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Flavonoids/*therapeutic use
Mitochondrial Diseases/*diagnosis
Mitochondrial Diseases/*prevention & control
Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Cytoprotection/drug effects ; Flavonoids/pharmacology ; Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitophagy/drug effects ; Oxidative Stress/drug effects ; Precision Medicine/methods ; Prognosis
Czasopismo naukowe
Tytuł :
Effect of Methyl Jasmonate on the Terpene Trilactones, Flavonoids, and Phenolic Acids in Ginkgo biloba L. Leaves: Relevance to Leaf Senescence.
Autorzy :
Horbowicz M; Department of Plant Physiology, Genetics and Biotechnology, University of Warmia and Mazury, Oczapowskiego 1a, 10-719 Olsztyn, Poland.
Wiczkowski W; Department of Chemistry and Biodynamics of Food, Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Tuwima 10, 10-748 Olsztyn, Poland.
Góraj-Koniarska J; Research Institute of Horticulture, Konstytucji 3 Maja 1/3, 96-100 Skierniewice, Poland.
Miyamoto K; Faculty of Liberal Arts and Sciences, Osaka Prefecture University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan.
Ueda J; Department of Biological Science, Graduate School of Science, Osaka Prefecture University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka 599-8531, Japan.
Saniewski M; Research Institute of Horticulture, Konstytucji 3 Maja 1/3, 96-100 Skierniewice, Poland.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 02; Vol. 26 (15). Date of Electronic Publication: 2021 Aug 02.
Typ publikacji :
Journal Article
MeSH Terms :
Cellular Senescence*
Cyclopentanes/*pharmacology
Flavonoids/*metabolism
Ginkgo biloba/*metabolism
Hydroxybenzoates/*metabolism
Lactones/*metabolism
Oxylipins/*pharmacology
Plant Leaves/*metabolism
Flavonoids/analysis ; Ginkgo biloba/drug effects ; Ginkgo biloba/growth & development ; Hydroxybenzoates/analysis ; Lactones/analysis ; Plant Growth Regulators/pharmacology ; Plant Leaves/drug effects ; Plant Leaves/growth & development ; Terpenes/analysis ; Terpenes/metabolism
Czasopismo naukowe
Tytuł :
Computational guided identification of a citrus flavonoid as potential inhibitor of SARS-CoV-2 main protease.
Autorzy :
Gogoi N; Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh, 786004, India.
Chowdhury P; Department of Health Research, Model Rural Health Research Unit, Tripura, 799035, India.
Goswami AK; Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh, 786004, India.
Das A; Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh, 786004, India.; Centre for Biotechnology and Bioinformatics, Faculty of Biological sciences, Dibrugarh University, Dibrugarh, 786004, India.
Chetia D; Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh, 786004, India.
Gogoi B; Department of Biotechnology, Royal School of Bio-Science, Royal Global University, Guwahati, 781035, India. .
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Źródło :
Molecular diversity [Mol Divers] 2021 Aug; Vol. 25 (3), pp. 1745-1759. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Discovery*
Citrus/*chemistry
Coronavirus 3C Proteases/*antagonists & inhibitors
Flavonoids/*pharmacology
Protease Inhibitors/*pharmacology
SARS-CoV-2/*enzymology
Coronavirus 3C Proteases/chemistry ; Coronavirus 3C Proteases/metabolism ; Flavonoids/metabolism ; Molecular Docking Simulation ; Protease Inhibitors/metabolism ; Protein Conformation ; Quercetin/analogs & derivatives ; Quercetin/metabolism ; Quercetin/pharmacology ; SARS-CoV-2/drug effects
Czasopismo naukowe

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