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Wyświetlanie 1-20 z 1522
Tytuł:
Frequency of DPYD gene variants and phenotype inference in a Southern Brazilian population.
Autorzy:
Botton MR; Department of Genetics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.; Cells, Tissues and Genes Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
Hentschke-Lopes M; Cells, Tissues and Genes Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.; Post Graduation Program on Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Matte U; Department of Genetics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.; Cells, Tissues and Genes Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.; Post Graduation Program on Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
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Źródło:
Annals of human genetics [Ann Hum Genet] 2022 Mar; Vol. 86 (2), pp. 102-107. Date of Electronic Publication: 2021 Dec 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dihydrouracil Dehydrogenase (NADP)*/genetics
Fluorouracil*/adverse effects
Alleles ; Brazil ; Gene Frequency ; Humans ; Phenotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative cytotoxic and antiproliferative profile of methotrexate and fluorouracil on different ocular cells.
Autorzy:
Schulz A; Eye Clinic Sulzbach, Klaus Heimann Eye Research Institute, Knappschaft Hospital Saar, Sulzbach, Germany.
Rickmann A; Eye Clinic Sulzbach, Klaus Heimann Eye Research Institute, Knappschaft Hospital Saar, Sulzbach, Germany.
Julich-Haertel H; Eye Clinic Sulzbach, Klaus Heimann Eye Research Institute, Knappschaft Hospital Saar, Sulzbach, Germany.
Germann A; Fraunhofer Institute for Biomedical Engineering, Sulzbach, Germany.
von Briesen H; Fraunhofer Institute for Biomedical Engineering, Sulzbach, Germany.
Januschowski K; Eye Clinic Sulzbach, Klaus Heimann Eye Research Institute, Knappschaft Hospital Saar, Sulzbach, Germany.; Centre for Ophthalmology, University Eye Hospital Tuebingen, Tuebingen, Germany.
Szurman P; Eye Clinic Sulzbach, Klaus Heimann Eye Research Institute, Knappschaft Hospital Saar, Sulzbach, Germany.
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Źródło:
Acta ophthalmologica [Acta Ophthalmol] 2021 Nov; Vol. 99 (7), pp. e1070-e1076. Date of Electronic Publication: 2020 Dec 30.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Fluorouracil/*adverse effects
Methotrexate/*adverse effects
Retinal Pigment Epithelium/*pathology
Vitreoretinopathy, Proliferative/*drug therapy
Apoptosis ; Cells, Cultured ; Fluorouracil/therapeutic use ; Humans ; Immunosuppressive Agents/adverse effects ; Immunosuppressive Agents/therapeutic use ; Methotrexate/therapeutic use ; Retinal Pigment Epithelium/drug effects ; Vitreoretinopathy, Proliferative/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy and safety of micro‐needling combined with topical 5‐fluorouracil and excimer light vs. excimer light alone in treatment of non‐segmental vitiligo: A comparative study.
Autorzy:
Saad, Mohammad A. (AUTHOR)
Tawfik, Khaled Mohamed (AUTHOR)
Abdelaleem, Hazem L. (AUTHOR)
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Źródło:
Journal of Cosmetic Dermatology. Mar2023, Vol. 22 Issue 3, p810-821. 12p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High therapeutic efficacy of 5-Fluorouracil-loaded exosomes against colon cancer cells.
Autorzy:
Shekh R; Department of Biosciences, Integral University, Kursi Road, India.
Ahmad A; Department of Biosciences, Integral University, Kursi Road, India.
Tiwari RK; Department of Biosciences, Integral University, Kursi Road, India.
Saeed M; Department of Biology, College of Sciences, University of Hail, Hail, Saudi Arabia.
Shukla R; Department of Clinical Research, Sharda School of Allied Health Sciences, Sharda University, Greater Noida, India.
Al-Thubiani WS; Department of Biology, Faculty of Applied Sciences, Umm Al-Qura University, Mecca, Saudi Arabia.
Ansari IA; Department of Biosciences, Integral University, Kursi Road, India.
Ashfaque M; Department of Biosciences, Integral University, Kursi Road, India.
Bajpai P; Department of Zoology, Mahatma Gandhi Central University, Motihari, India.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2023 Apr; Vol. 101 (4), pp. 962-976. Date of Electronic Publication: 2023 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Exosomes*/metabolism
Exosomes*/pathology
Colonic Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Humans ; Fluorouracil ; Apoptosis ; Cell Line, Tumor ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The efficacy of microneedling alone vs its combination with 5-fluorouracil solution vs 5-fluorouracil intralesional injection in the treatment of plantar warts.
Autorzy:
Ghonemy S; Faculty of Medicine, Department of Dermatology, Zagazig University, Zagazig, Egypt.
Ibrahim Ali M; Faculty of Medicine, Department of Dermatology, Zagazig University, Zagazig, Egypt.
Ebrahim HM; Faculty of Medicine, Department of Dermatology, Zagazig University, Zagazig, Egypt.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2020 Nov; Vol. 33 (6), pp. e14179. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Fluorouracil*/adverse effects
Warts*/diagnosis
Warts*/drug therapy
Humans ; Injections, Intralesional ; Pain ; Recurrence ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
5-Fluorouracil reduces the fibrotic scar via inhibiting matrix metalloproteinase 9 and stabilizing microtubules after spinal cord injury.
Autorzy:
Xu Y; Institute of Neurological Disease, West China Hospital, Sichuan University & The Research Units of West China, Chinese Academy of Medical Sciences, Chengdu, China.; Laboratory of Anesthesia and Critical Care Medicine, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, China.
He X; Institute of Neurological Disease, West China Hospital, Sichuan University & The Research Units of West China, Chinese Academy of Medical Sciences, Chengdu, China.; Laboratory of Anesthesia and Critical Care Medicine, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, China.
Wang Y; Institute of Neurological Disease, West China Hospital, Sichuan University & The Research Units of West China, Chinese Academy of Medical Sciences, Chengdu, China.
Jian J; Institute of Neuroscience, Laboratory Zoology Department, Kunming Medical University, Kunming, China.
Peng X; Institute of Neuroscience, Laboratory Zoology Department, Kunming Medical University, Kunming, China.
Zhou L; Yunnan Key Laboratory of Stem Cell and Regenerative Medicine, Biomedical Engineering Research Center, Kunming Medical University, Kunming, China.
Kang Y; Laboratory of Anesthesia and Critical Care Medicine, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, China.; National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Wang T; Institute of Neurological Disease, West China Hospital, Sichuan University & The Research Units of West China, Chinese Academy of Medical Sciences, Chengdu, China.; Institute of Neuroscience, Laboratory Zoology Department, Kunming Medical University, Kunming, China.; National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2022 Dec; Vol. 28 (12), pp. 2011-2023. Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cicatrix*/pathology
Spinal Cord Injuries*/pathology
Animals ; Matrix Metalloproteinase 9/pharmacology ; Matrix Metalloproteinase 9/therapeutic use ; Fluorouracil/pharmacology ; Fluorouracil/therapeutic use ; Disease Models, Animal ; Microtubules/metabolism ; Microtubules/pathology ; Spinal Cord/pathology ; Nerve Regeneration/physiology ; Axons
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy and safety of combined fractional ablative CO2 laser and 5 fluorouracil in the treatment of acral vitiligo: An open, uncontrolled study.
Autorzy:
Weshahy, Ragia (AUTHOR)
Abdelhamid, Mahmoud F. (AUTHOR)
Sayed, Khadiga S. (AUTHOR)
El Desouky, Eman D. (AUTHOR)
Ramez, Shahenda A. (AUTHOR)
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Źródło:
Journal of Cosmetic Dermatology. Nov2022, Vol. 21 Issue 11, p5636-5641. 6p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comprehensive treatment of basal cell carcinoma in nevoid basal cell carcinoma syndrome with 5-fluorouracil and salicylic acid.
Autorzy:
Yu Y; Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan Province, People's Republic of China.
Zhang G; Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan Province, People's Republic of China.
Fu S; Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan Province, People's Republic of China.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2022 Dec; Vol. 35 (12), pp. e15972. Date of Electronic Publication: 2022 Nov 16.
Typ publikacji:
Letter
MeSH Terms:
Basal Cell Nevus Syndrome*/drug therapy
Basal Cell Nevus Syndrome*/pathology
Carcinoma, Basal Cell*/drug therapy
Skin Neoplasms*/drug therapy
Humans ; Fluorouracil ; Salicylic Acid
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Norwich trabeculectomy study: risk factor analysis for the development of adverse, thin cystic blebs.
Autorzy:
Al-Mugheiry TS; Norfolk & Norwich University Hospital NHS Foundation Trust, Norwich, UK.
Clark A; Norwich Medical School, University of East Anglia, Norwich, UK.
Broadway DC; Norfolk & Norwich University Hospital NHS Foundation Trust, Norwich, UK.; Norwich Medical School, University of East Anglia, Norwich, UK.; School of Pharmacy, University of East Anglia, Norwich, UK.
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Źródło:
Acta ophthalmologica [Acta Ophthalmol] 2022 Nov; Vol. 100 (7), pp. e1463-e1469. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Glaucoma*/etiology
Glaucoma*/surgery
Trabeculectomy*/adverse effects
Trabeculectomy*/methods
Humans ; Antimetabolites/adverse effects ; Conjunctiva/surgery ; Factor Analysis, Statistical ; Fluorouracil ; Intraocular Pressure ; Mitomycin ; Regulatory Factor X1 ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis.
Autorzy:
Attwa E; Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Khater MH; Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Selim HM; Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Essam R; Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2022 Nov; Vol. 35 (11), pp. e15796. Date of Electronic Publication: 2022 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Keloid*/drug therapy
Psoriasis*/diagnosis
Psoriasis*/drug therapy
Psoriasis*/chemically induced
Hyperpigmentation*/chemically induced
Humans ; Triamcinolone Acetonide ; Drug Therapy, Combination ; Injections, Intralesional ; Fluorouracil ; Pain/drug therapy ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of the efficacy of intralesional 5-fluorouracil/lidocaine/epinephrine injection with cryotherapy to treat common and palmoplantar warts: A randomized, controlled trial.
Autorzy:
Sepaskhah M; Department of Dermatology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.; Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Sarani MB; Department of Dermatology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Bagheri Z; Department of Biostatistics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2022 Sep; Vol. 35 (9), pp. e15726. Date of Electronic Publication: 2022 Jul 31.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Lidocaine*/therapeutic use
Warts*/diagnosis
Warts*/therapy
Cryotherapy ; Epinephrine/therapeutic use ; Fluorouracil ; Humans ; Injections, Intralesional ; Pain/drug therapy ; Pain/etiology ; Quality of Life ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Blockage of PD-L1 by FERMT3-mediated Wnt/β-catenin signalling regulates chemoresistance and immune evasion of colorectal cancer cells.
Autorzy:
Tang Y; Department of Gastrointestinal Surgery, The First People's Hospital of Gui Yang, Gui Yang, China.
Nan N; Department of Pathology, The First People's Hospital of Gui Yang, Gui Yang, China.
Gui C; Department of Pathology, The First People's Hospital of Gui Yang, Gui Yang, China.
Zhou X; Department of Science and education, The First People's Hospital of Gui Yang, Gui Yang, China.
Jiang W; Department of Nephrology, The First People's Hospital of Gui Yang, Gui Yang, China.
Zhou X; Department of Gastroenterology, The First People's Hospital of Gui Yang, Gui Yang, China.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2022 Sep; Vol. 49 (9), pp. 988-997. Date of Electronic Publication: 2022 Jun 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B7-H1 Antigen*/metabolism
Colorectal Neoplasms*/genetics
Cell Line, Tumor ; Drug Resistance, Neoplasm ; Fluorouracil/pharmacology ; Fluorouracil/therapeutic use ; Gene Expression Regulation, Neoplastic ; Humans ; Immune Evasion ; Membrane Proteins ; Neoplasm Proteins ; Wnt Signaling Pathway ; beta Catenin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microneedling and 5-flurouracil can enhance the efficacy of non-cultured epidermal cell suspension transplantation for resistant acral vitiligo.
Autorzy:
Albalat W; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Elsayed M; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Salem A; Dermato-Pathology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Ehab R; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Fawzy M; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2022 Oct; Vol. 35 (10), pp. e15768. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article
MeSH Terms:
Vitiligo*/surgery
Vitiligo*/therapy
Fluorouracil ; Humans ; Melanocytes ; Skin Pigmentation ; Transplantation, Autologous ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Topical calcipotriol combined with urea 20% versus intralesional injection of triamcinolone acetonide, 5-fluorouracil, and methotrexate in the treatment of nail psoriasis: A comparative study.
Autorzy:
Abdelmeniem IM; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
El Eryan IM; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Nofal A; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Fouda I; Department of Dermatology, Venereology and Andrology, Damietta Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Omar SS; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2022 Sep; Vol. 35 (9), pp. e15660. Date of Electronic Publication: 2022 Jul 11.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Dermatologic Agents*
Nail Diseases*/diagnosis
Nail Diseases*/drug therapy
Psoriasis*/diagnosis
Psoriasis*/drug therapy
Calcitriol/analogs & derivatives ; Fluorouracil/adverse effects ; Humans ; Injections, Intralesional ; Methotrexate ; Treatment Outcome ; Triamcinolone Acetonide/adverse effects ; Urea
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pristine and alkali and alkaline earth metals encapsulated B36N36 nanoclusters as prospective delivery agents and detectors for 5‐fluorouracil anticancer drug.
Autorzy:
Shakerzadeh, Ehsan (AUTHOR)
Zborowski, Krzysztof K. (AUTHOR)
Anota, Ernesto Chigo (AUTHOR)
Nguyen, Minh Tho (AUTHOR)
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Źródło:
Applied Organometallic Chemistry. Jul2022, Vol. 36 Issue 7, p1-10. 10p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microneedling combined with pimecrolimus, 5-fluorouracil, and trichloroacetic acid in the treatment of vitiligo: A comparative study.
Autorzy:
Nofal A; Dermatology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Eldeeb F; Dermatology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Shalaby M; Dermatology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Al-Balat W; Dermatology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
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Źródło:
Dermatologic therapy [Dermatol Ther] 2022 Mar; Vol. 35 (3), pp. e15294. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Trichloroacetic Acid*/adverse effects
Vitiligo*/chemically induced
Vitiligo*/diagnosis
Vitiligo*/therapy
Combined Modality Therapy ; Fluorouracil ; Humans ; Tacrolimus/analogs & derivatives ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 1522

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