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Tytuł:
Induction of double-strand breaks with the non-steroidal androgen receptor ligand flutamide in patients on androgen suppression: a study protocol for a randomized, double-blind prospective trial.
Autorzy:
Lee E; Johns Hopkins University School of Medicine, Baltimore, USA.
Coulter J; Department of Urology, Johns Hopkins University, Baltimore, USA.
Mishra A; Department of Oncology, Johns Hopkins University, Baltimore, USA.
Caramella-Pereira F; Oncology Pathology, Johns Hopkins University, Baltimore, USA.
Demarzo A; Oncology Pathology, Johns Hopkins University, Baltimore, USA.
Rudek M; Department of Oncology, Johns Hopkins University, Baltimore, USA.
Hu C; Department of Biostatistics, Johns Hopkins University, Baltimore, USA.
Han M; Department of Urology, Johns Hopkins University, Baltimore, USA.
DeWeese TL; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, USA.
Yegnasubramanian S; Department of Urology, Johns Hopkins University, Baltimore, USA.; Department of Oncology, Johns Hopkins University, Baltimore, USA.
Song DY; Department of Urology, Johns Hopkins University, Baltimore, USA. .; Department of Oncology, Johns Hopkins University, Baltimore, USA. .; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, USA. .
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Źródło:
Trials [Trials] 2023 Dec 16; Vol. 24 (1), pp. 809. Date of Electronic Publication: 2023 Dec 16.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Flutamide*/therapeutic use
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/pathology
Male ; Humans ; Androgens ; Androgen Antagonists/therapeutic use ; Receptors, Androgen ; Ligands ; Prospective Studies ; Treatment Outcome ; DNA ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Resistance to 2-Hydroxy-Flutamide in Prostate Cancer Cells Is Associated with the Downregulation of Phosphatidylcholine Biosynthesis and Epigenetic Modifications.
Autorzy:
Mora-Rodríguez JM; Biochemistry and Molecular Biology Unit, Department of Systems Biology, School of Medicine and Health Sciences, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.; Health Research Institute of Castilla-La Mancha (IDISCAM), 13700 Tomelloso, Ciudad Real, Spain.
Sánchez BG; Biochemistry and Molecular Biology Unit, Department of Systems Biology, School of Medicine and Health Sciences, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.; Health Research Institute of Castilla-La Mancha (IDISCAM), 13700 Tomelloso, Ciudad Real, Spain.
Sebastián-Martín A; Biochemistry and Molecular Biology Unit, Department of Systems Biology, School of Medicine and Health Sciences, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.; Health Research Institute of Castilla-La Mancha (IDISCAM), 13700 Tomelloso, Ciudad Real, Spain.
Díaz-Yuste A; Biochemistry and Molecular Biology Unit, Department of Systems Biology, School of Medicine and Health Sciences, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.; Health Research Institute of Castilla-La Mancha (IDISCAM), 13700 Tomelloso, Ciudad Real, Spain.
Sánchez-Chapado M; Department of Urology, Príncipe de Asturias Hospital, 28805 Alcalá de Henares, Madrid, Spain.
Palacín AM; Department of Urology, Príncipe de Asturias Hospital, 28805 Alcalá de Henares, Madrid, Spain.
Sánchez-Rodríguez C; Department of Urology, Príncipe de Asturias Hospital, 28805 Alcalá de Henares, Madrid, Spain.
Bort A; Biochemistry and Molecular Biology Unit, Department of Systems Biology, School of Medicine and Health Sciences, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.; Health Research Institute of Castilla-La Mancha (IDISCAM), 13700 Tomelloso, Ciudad Real, Spain.; Department of Comparative Medicine, School of Medicine, Yale University, New Haven, CT 06519, USA.
Díaz-Laviada I; Biochemistry and Molecular Biology Unit, Department of Systems Biology, School of Medicine and Health Sciences, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.; Health Research Institute of Castilla-La Mancha (IDISCAM), 13700 Tomelloso, Ciudad Real, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 26; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Flutamide*/pharmacology
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/genetics
Prostatic Neoplasms*/metabolism
Male ; Humans ; Down-Regulation ; Androgen Antagonists/pharmacology ; Cell Line, Tumor ; Transferases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The High Stability and Selectivity of Electrochemical Sensor Using Low-Cost Diamond Nanoparticles for the Detection of Anti-Cancer Drug Flutamide in Environmental Samples.
Autorzy:
Baskaran N; Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei 10608, Taiwan.
Prasanna SB; Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei 10608, Taiwan.
Lin YC; Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei 10608, Taiwan.; School of Materials Science and Engineering, Nanyang Technological University, Singapore 639798, Singapore.
Duann YF; Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei 10608, Taiwan.
Chung RJ; Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei 10608, Taiwan.; High-Value Biomaterials Research and Commercialization Center, National Taipei University of Technology, Taipei 10608, Taiwan.
Wei Y; Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei 10608, Taiwan.; High-Value Biomaterials Research and Commercialization Center, National Taipei University of Technology, Taipei 10608, Taiwan.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2024 Feb 02; Vol. 24 (3). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*
Nanoparticles*/chemistry
Flutamide/chemistry ; Carbon/chemistry ; Water ; Electrochemical Techniques/methods ; Electrodes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activation of testosterone-androgen receptor mediates cerebrovascular protection by photobiomodulation treatment in photothrombosis-induced stroke rats.
Autorzy:
Feng Y; Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Huang Z; Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Ma X; Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Zong X; Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Wu CY; Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Lee RH; Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Lin HW; Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Hamblin MR; Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Zhang Q; Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14574.
Typ publikacji:
Journal Article
MeSH Terms:
Low-Level Light Therapy*
Stroke*/therapy
Humans ; Male ; Rats ; Mice ; Animals ; Testosterone/metabolism ; Androgens/metabolism ; Receptors, Androgen/metabolism ; Endothelial Cells/metabolism ; Flutamide/pharmacology ; Flutamide/therapeutic use ; Flutamide/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
PCDH1, a poor prognostic biomarker and potential target for pancreatic adenocarcinoma metastatic therapy.
Autorzy:
Du X; Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, 110016, China.; State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology, Beijing, 100850, China.; Nanhu Laboratory, Jiaxing, 314002, China.
Yi X; State Key Laboratory of Proteomics, Institute of Basic Medical Sciences, National Center of Biomedical Analysis, Beijing, 100850, China.; Nanhu Laboratory, Jiaxing, 314002, China.
Zou X; Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, 110016, China.; State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology, Beijing, 100850, China.
Chen Y; State Key Laboratory of Proteomics, Institute of Basic Medical Sciences, National Center of Biomedical Analysis, Beijing, 100850, China.; Nanhu Laboratory, Jiaxing, 314002, China.
Tai Y; Department of Pathology, No.307 Hospital of PLA, Beijing, 100071, China.
Ren X; Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, 110016, China. .
He X; State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology, Beijing, 100850, China. .; Nanhu Laboratory, Jiaxing, 314002, China. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Nov 13; Vol. 23 (1), pp. 1102. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma*
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Humans ; Prognosis ; Flutamide ; RNA ; Biomarkers ; Gene Expression Regulation, Neoplastic ; Protocadherins ; Pancreatic Neoplasms
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development and Evaluation of Tc Tricarbonyl Complexes Derived from Flutamide with Affinity for Androgen Receptor.
Autorzy:
Cardoso ME; Radiochemistry Area, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Decuadra P; Radiochemistry Area, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Zeni M; Radiochemistry Area, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Delfino A; Organic Chemistry Department, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Tejería E; Radiochemistry Area, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Coppe F; Centro de Medicina Nuclear e Imagenología Molecular-Hospital de Clínicas, Facultad de Medicina, Universidad de la República, Av.Italia s/n, Montevideo CP11400, Uruguay.
Mesa JM; Organic Chemistry Department, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Daher G; Organic Chemistry Department, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Giglio J; Radiochemistry Area, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Carrau G; Organic Chemistry Department, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Gamenara D; Organic Chemistry Department, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Alonso O; Centro de Medicina Nuclear e Imagenología Molecular-Hospital de Clínicas, Facultad de Medicina, Universidad de la República, Av.Italia s/n, Montevideo CP11400, Uruguay.
Terán M; Radiochemistry Area, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
Rey A; Radiochemistry Area, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo CP11800, Uruguay.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jan 13; Vol. 28 (2). Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:
Journal Article
MeSH Terms:
Flutamide*/pharmacology
Receptors, Androgen*
Male ; Humans ; Diagnostic Imaging ; Radiopharmaceuticals/chemistry ; Technetium/chemistry ; Organotechnetium Compounds/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lncap-AI prostate cancer cell line establishment by Flutamide and androgen-free environment to promote cell adherent.
Autorzy:
Wang H; Department of Human Anatomy, School of Basic Medical Sciences, Guangxi Medical University, 530021, Nanning, Guangxi, China.; Key Laboratory of Human Development and Disease Research, Education Department of Guangxi Zhuang Autonomous Region, Guangxi Medical University, Guangxi, 530021, Nanning, China.
Wei X; Institute of Life Sciences, Guangxi Medical University, 530021, Nanning, Guangxi, China.
Zhang D; Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry, Guangxi Medical University, 530021, Nanning, Guangxi, China.
Li W; Institute of Life Sciences, Guangxi Medical University, 530021, Nanning, Guangxi, China.
Hu Y; Institute of Life Sciences, Guangxi Medical University, 530021, Nanning, Guangxi, China. .
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Źródło:
BMC molecular and cell biology [BMC Mol Cell Biol] 2022 Nov 28; Vol. 23 (1), pp. 51. Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Flutamide*
Prostatic Neoplasms, Castration-Resistant*/drug therapy
Prostatic Neoplasms, Castration-Resistant*/genetics
Male ; Humans ; Androgens/pharmacology ; Androgen Antagonists/pharmacology ; Prostate-Specific Antigen ; Sincalide ; Cell Line
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The effect of Ganoderma lucidum polysaccharide extract on sensitizing prostate cancer cells to flutamide and docetaxel: an in vitro study.
Autorzy:
Rahimnia R; Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Akbari MR; Women's College Research Institute, Women's College Hospital, University of Toronto, Toronto, Canada.; Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Canada.
Yasseri AF; Alborz University of Medical Sciences, Shariati Hospital, Alborz, Iran.
Taheri D; Isfahan Kidney Disease Research Center, Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran.; Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mirzaei A; Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Ghajar HA; Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Farashah PD; Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Baghdadabad LZ; Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Aghamir SMK; Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 02; Vol. 13 (1), pp. 18940. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Reishi*
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/metabolism
Male ; Humans ; Docetaxel/pharmacology ; Docetaxel/therapeutic use ; Prostate/metabolism ; Flutamide/pharmacology ; Cell Line, Tumor ; Polysaccharides/pharmacology ; Polysaccharides/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison between "5% minoxidil plus 2% flutamide" solution vs. "5% minoxidil" solution in the treatment of androgenetic alopecia.
Autorzy:
Faghihi G; Dermatology Department, Isfahan University of Medical Sciences, Isfahan, Iran.
Iraji F; Dermatology Department, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Siadat AH; Department of Dermatology, Skin Diseases and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Saber M; Department of Dermatology, Skin Diseases and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Jelvan M; Department of Dermatology, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Hoseyni MS; Isfahan University of Medical Sciences, Isfahan, Iran.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2022 Oct; Vol. 21 (10), pp. 4447-4453. Date of Electronic Publication: 2022 Feb 18.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Minoxidil*
Flutamide*/therapeutic use
Humans ; Treatment Outcome ; Alopecia/diagnosis ; Alopecia/drug therapy ; Alopecia/chemically induced ; Finasteride ; Administration, Topical
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluation of covalent binding of flutamide and its risk assessment using F-NMR.
Autorzy:
Kakutani N; Drug Metabolism and Pharmacokinetics Research Laboratories, Japan Tobacco Inc, Takatsuki, Japan.
Iwai T; Product Development Laboratories, Japan Tobacco Inc, Takatsuki, Japan.
Ohno Y; Product Development Laboratories, Japan Tobacco Inc, Takatsuki, Japan.
Kobayashi S; Drug Metabolism and Pharmacokinetics Research Laboratories, Japan Tobacco Inc, Takatsuki, Japan.
Nomura Y; Drug Metabolism and Pharmacokinetics Research Laboratories, Japan Tobacco Inc, Takatsuki, Japan.
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Źródło:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Jan; Vol. 51 (1), pp. 88-94. Date of Electronic Publication: 2020 Sep 22.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents, Hormonal/*toxicity
Flutamide/*toxicity
Antineoplastic Agents, Hormonal/metabolism ; Chemical and Drug Induced Liver Injury ; Drug-Related Side Effects and Adverse Reactions ; Flutamide/metabolism ; Humans ; Magnetic Resonance Spectroscopy ; Microsomes, Liver/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Effect of Various Poly (N -vinylpyrrolidone) (PVP) Polymers on the Crystallization of Flutamide.
Autorzy:
Heczko, Dawid (AUTHOR)
Hachuła, Barbara (AUTHOR)
Maksym, Paulina (AUTHOR)
Kamiński, Kamil (AUTHOR)
Zięba, Andrzej (AUTHOR)
Orszulak, Luiza (AUTHOR)
Paluch, Marian (AUTHOR)
Kamińska, Ewa (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). Aug2022, Vol. 15 Issue 8, p971-971. 20p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Disruption of androgen signaling during puberty affects Notch pathway in rat seminiferous epithelium.
Autorzy:
Kamińska A; Department of Endocrinology, Faculty of Biology, Institute of Zoology & Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387, Krakow, Poland.
Marek S; Department of Endocrinology, Faculty of Biology, Institute of Zoology & Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387, Krakow, Poland.
Pardyak L; Department of Endocrinology, Faculty of Biology, Institute of Zoology & Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387, Krakow, Poland.
Brzoskwinia M; Department of Endocrinology, Faculty of Biology, Institute of Zoology & Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387, Krakow, Poland.
Pawlicki P; Department of Endocrinology, Faculty of Biology, Institute of Zoology & Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387, Krakow, Poland.
Bilińska B; Department of Endocrinology, Faculty of Biology, Institute of Zoology & Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387, Krakow, Poland.
Hejmej A; Department of Endocrinology, Faculty of Biology, Institute of Zoology & Biomedical Research, Jagiellonian University, Gronostajowa 9, 30-387, Krakow, Poland. .
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Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2020 Apr 16; Vol. 18 (1), pp. 30. Date of Electronic Publication: 2020 Apr 16.
Typ publikacji:
Journal Article
MeSH Terms:
Flutamide/*pharmacology
Receptors, Androgen/*metabolism
Receptors, Notch/*metabolism
Seminiferous Epithelium/*drug effects
Sexual Maturation/*physiology
Signal Transduction/*drug effects
Androgen Antagonists/administration & dosage ; Androgen Antagonists/pharmacology ; Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Flutamide/administration & dosage ; Gene Expression/drug effects ; Humans ; Jagged-1 Protein/genetics ; Jagged-1 Protein/metabolism ; Male ; Rats, Wistar ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Seminiferous Epithelium/metabolism ; Testosterone/metabolism ; Transcription Factor HES-1/genetics ; Transcription Factor HES-1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enzalutamide versus flutamide for castration-resistant prostate cancer after combined androgen blockade therapy with bicalutamide: study protocol for a multicenter randomized phase II trial (the OCUU-CRPC study).
Autorzy:
Iguchi T; Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan. .
Tamada S; Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Kato M; Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Yasuda S; Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Yamasaki T; Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Nakatani T; Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
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Źródło:
BMC cancer [BMC Cancer] 2019 Apr 11; Vol. 19 (1), pp. 339. Date of Electronic Publication: 2019 Apr 11.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Clinical Protocols*
Flutamide/*therapeutic use
Phenylthiohydantoin/*analogs & derivatives
Prostatic Neoplasms, Castration-Resistant/*drug therapy
Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Benzamides ; Flutamide/administration & dosage ; Flutamide/adverse effects ; Humans ; Male ; Nitriles ; Phenylthiohydantoin/administration & dosage ; Phenylthiohydantoin/adverse effects ; Phenylthiohydantoin/therapeutic use ; Prostatic Neoplasms, Castration-Resistant/diagnosis ; Research Design ; Retreatment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Very low dose of flutamide in the treatment of hyperandrogenism.
Autorzy:
Fulghesu AM; a Department of Obstetric and Gynecology , Univ di Cagliari , Cagliari , Italy.
Melis F; a Department of Obstetric and Gynecology , Univ di Cagliari , Cagliari , Italy.
Murru G; b Department of Obstetrics and Gynecology , Ospedale San Paolo, Università di Milano , Milano , Italy.
Canu E; a Department of Obstetric and Gynecology , Univ di Cagliari , Cagliari , Italy.
Melis GB; a Department of Obstetric and Gynecology , Univ di Cagliari , Cagliari , Italy.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2018 May; Vol. 34 (5), pp. 394-398. Date of Electronic Publication: 2017 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
Acne Vulgaris/*drug therapy
Androgen Antagonists/*therapeutic use
Flutamide/*therapeutic use
Hirsutism/*drug therapy
Hyperandrogenism/*drug therapy
Adolescent ; Androgen Antagonists/administration & dosage ; Androstenes/administration & dosage ; Androstenes/therapeutic use ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Ethinyl Estradiol/administration & dosage ; Ethinyl Estradiol/therapeutic use ; Female ; Flutamide/administration & dosage ; Humans ; Norpregnenes/administration & dosage ; Norpregnenes/therapeutic use ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Response to flutamide, as second-line therapy after bicalutamide, predicts efficacy of abiraterone, not that of enzalutamide.
Autorzy:
Nakai Y; Department of Urology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Tanaka N; Department of Urology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan. .
Miyake M; Department of Urology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Inoue T; Department of Urology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Anai S; Department of Urology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
Fujimoto K; Department of Urology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
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Źródło:
BMC research notes [BMC Res Notes] 2018 May 29; Vol. 11 (1), pp. 342. Date of Electronic Publication: 2018 May 29.
Typ publikacji:
Journal Article
MeSH Terms:
Outcome Assessment, Health Care*
Androstenes/*pharmacology
Anilides/*pharmacology
Antineoplastic Agents/*pharmacology
Flutamide/*pharmacology
Nitriles/*pharmacology
Phenylthiohydantoin/*analogs & derivatives
Prostatic Neoplasms, Castration-Resistant/*drug therapy
Tosyl Compounds/*pharmacology
Aged ; Aged, 80 and over ; Androstenes/administration & dosage ; Anilides/administration & dosage ; Antineoplastic Agents/administration & dosage ; Benzamides ; Disease-Free Survival ; Flutamide/administration & dosage ; Humans ; Male ; Middle Aged ; Nitriles/administration & dosage ; Phenylthiohydantoin/administration & dosage ; Phenylthiohydantoin/pharmacology ; Prostate-Specific Antigen ; Retrospective Studies ; Tosyl Compounds/administration & dosage
Czasopismo naukowe
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Wyświetlanie 1-20 z 2489

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