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Tytuł :
Mycobacterial antigens accumulation in foamy macrophages in murine pulmonary tuberculosis lesions: Association with necrosis and making of cavities.
Autorzy :
Riaz SM; Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Bjune GA; Department of Community Medicine, Institute of Health and Society, The Faculty of Medicine, University of Oslo, Oslo, Norway.
Wiker HG; Department of Clinical Science, University of Bergen, Bergen, Norway.
Sviland L; Department of Clinical Medicine, University of Bergen, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway.
Mustafa T; Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.; Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.
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Źródło :
Scandinavian journal of immunology [Scand J Immunol] 2020 Apr; Vol. 91 (4), pp. e12866. Date of Electronic Publication: 2020 Feb 18.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0323767 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-3083 (Electronic) Linking ISSN: 03009475 NLM ISO Abbreviation: Scand. J. Immunol. Subsets: MEDLINE
MeSH Terms :
Antigens, Bacterial/*immunology
Foam Cells/*immunology
Foam Cells/*microbiology
Tuberculosis, Pulmonary/*pathology
Animals ; Foam Cells/pathology ; Mice ; Mycobacterium tuberculosis ; Necrosis ; Tuberculosis, Pulmonary/immunology
Czasopismo naukowe
Tytuł :
Probucol-induced hypocholesterolemia is not associated with exacerbated foam cell formation in ABCG1 knockout mice.
Autorzy :
Hoekstra M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Einsteinweg 55, 2333CC, Leiden, the Netherlands. Electronic address: .
Van Eck M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Einsteinweg 55, 2333CC, Leiden, the Netherlands.
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Źródło :
Atherosclerosis [Atherosclerosis] 2020 Mar; Vol. 296, pp. 91-92. Date of Electronic Publication: 2020 Jan 30.
Typ publikacji :
Letter; Comment
Journal Info :
Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE
MeSH Terms :
Atherosclerosis*
Foam Cells*
ATP Binding Cassette Transporter, Subfamily G, Member 1 ; Animals ; Apolipoproteins E ; Bone Marrow ; Mice ; Mice, Knockout ; Mice, Knockout, ApoE ; Probucol
Opinia redakcyjna
Tytuł :
Gynura procumbens ethanol extract and its fractions inhibit macrophage derived foam cell formation.
Autorzy :
Manogaran M; Regenerative Medicine Cluster, Malaysia.
Vuanghao L; Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia.
Mohamed R; Regenerative Medicine Cluster, Malaysia. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2020 Mar 01; Vol. 249, pp. 112410. Date of Electronic Publication: 2019 Nov 17.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
MeSH Terms :
Asteraceae/*chemistry
Atherosclerosis/*prevention & control
Foam Cells/*drug effects
Plant Extracts/*pharmacology
ATP Binding Cassette Transporter 1/metabolism ; Animals ; Atherosclerosis/blood ; Ethanol/chemistry ; Foam Cells/metabolism ; Humans ; Interleukin-1beta/metabolism ; Lipoproteins, LDL/metabolism ; Malaysia ; Medicine, Traditional/methods ; Mice ; Plant Extracts/isolation & purification ; Plant Extracts/therapeutic use ; RAW 264.7 Cells ; Scavenger Receptors, Class E/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Contrasting effects of membrane enrichment with polyunsaturated fatty acids on phospholipid composition and cholesterol efflux from cholesterol-loaded J774 mouse or primary human macrophages.
Autorzy :
Fournier N; Lip(Sys)(2) - EA 7357, Athérosclérose: homéostasie et trafic du cholestérol des macrophages, Univ. Paris-Sud, Université Paris-Saclay, UFR de Pharmacie, 92290 Châtenay-Malabry, France; Laboratoire de Biochimie, AP-HP (Assistance Publique-Hôpitaux de Paris), Hôpital Européen Georges Pompidou, 75015 Paris, France. Electronic address: .
Benoist JF; Lip(Sys)(2) - EA 7357, Athérosclérose: homéostasie et trafic du cholestérol des macrophages, Univ. Paris-Sud, Université Paris-Saclay, UFR de Pharmacie, 92290 Châtenay-Malabry, France; Laboratoire de Biochimie hormonale, AP-HP (Assistance Publique-Hôpitaux de Paris), Hôpital Robert Debré, 75019 Paris, France.
Allaoui F; Lip(Sys)(2) - EA 7357, Athérosclérose: homéostasie et trafic du cholestérol des macrophages, Univ. Paris-Sud, Université Paris-Saclay, UFR de Pharmacie, 92290 Châtenay-Malabry, France.
Nowak M; Lip(Sys)(2) - EA 7357, Athérosclérose: homéostasie et trafic du cholestérol des macrophages, Univ. Paris-Sud, Université Paris-Saclay, UFR de Pharmacie, 92290 Châtenay-Malabry, France.
Dakroub H; Lip(Sys)(2) - EA 7357, Athérosclérose: homéostasie et trafic du cholestérol des macrophages, Univ. Paris-Sud, Université Paris-Saclay, UFR de Pharmacie, 92290 Châtenay-Malabry, France.
Vedie B; Laboratoire de Biochimie, AP-HP (Assistance Publique-Hôpitaux de Paris), Hôpital Européen Georges Pompidou, 75015 Paris, France.
Paul JL; Lip(Sys)(2) - EA 7357, Athérosclérose: homéostasie et trafic du cholestérol des macrophages, Univ. Paris-Sud, Université Paris-Saclay, UFR de Pharmacie, 92290 Châtenay-Malabry, France; Laboratoire de Biochimie, AP-HP (Assistance Publique-Hôpitaux de Paris), Hôpital Européen Georges Pompidou, 75015 Paris, France.
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Źródło :
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2020 Feb; Vol. 1865 (2), pp. 158536. Date of Electronic Publication: 2019 Oct 29.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731727 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2618 (Electronic) Linking ISSN: 13881981 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Biol Lipids Subsets: MEDLINE
MeSH Terms :
Arachidonic Acid/*administration & dosage
Cell Membrane/*drug effects
Cholesterol/*metabolism
Docosahexaenoic Acids/*administration & dosage
Eicosapentaenoic Acid/*administration & dosage
Foam Cells/*drug effects
ATP Binding Cassette Transporter 1/metabolism ; Animals ; Atherosclerosis/etiology ; Atherosclerosis/prevention & control ; Cell Line, Tumor ; Cell Membrane/metabolism ; Cholesterol/administration & dosage ; Cholesterol/adverse effects ; Dietary Supplements ; Foam Cells/cytology ; Foam Cells/metabolism ; Healthy Volunteers ; Humans ; Mice ; Phospholipids/metabolism ; Primary Cell Culture
Czasopismo naukowe
Tytuł :
Blood miR-1275 is associated with risk of ischemic stroke and inhibits macrophage foam cell formation by targeting ApoC2 gene.
Autorzy :
Li L; Research Center of Translational Medicine, The Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Xu W; Research Center of Translational Medicine, The Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Fu X; Department of Neurology, People's Hospital of Shenzhen, Guangdong, China.
Huang Y; Department of Neurology, People's Hospital of Shenzhen, Guangdong, China.
Wen Y; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
Xu Q; Department of Neurology, People's Hospital of Shenzhen, Guangdong, China.
He X; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China.
Wang K; Research Center of Translational Medicine, The Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Huang S; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China. Electronic address: .
Lv Z; Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Mar 20; Vol. 731, pp. 144364. Date of Electronic Publication: 2020 Jan 11.
Typ publikacji :
Journal Article; Validation Study
Journal Info :
Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0038 (Electronic) Linking ISSN: 03781119 NLM ISO Abbreviation: Gene Subsets: MEDLINE
MeSH Terms :
Apolipoprotein C-II/*genetics
Foam Cells/*pathology
MicroRNAs/*blood
Stroke/*genetics
Apolipoprotein C-II/metabolism ; Atherosclerosis/blood ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Brain Ischemia/blood ; Brain Ischemia/complications ; Brain Ischemia/genetics ; Case-Control Studies ; Cohort Studies ; Female ; Foam Cells/metabolism ; Gene Expression Regulation ; HEK293 Cells ; Humans ; Macrophages/pathology ; Macrophages/physiology ; Male ; MicroRNAs/physiology ; Risk Factors ; Stroke/blood ; THP-1 Cells
Czasopismo naukowe
Tytuł :
MicroRNA-23a suppresses the apoptosis of inflammatory macrophages and foam cells in atherogenesis by targeting HSP90.
Autorzy :
Qiao Y; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Wang C; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Translational Medicine Center of Northern China, Harbin Medical University, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Kou J; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Wang L; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Han D; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Huo D; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Li F; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Zhou X; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Meng D; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Xu J; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Murtaza G; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Artyom B; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China.
Ma N; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin, China; Medical Science Institute of Hei Longjiang Province, Harbin, China. Electronic address: .
Luo S; Department of Gerontology, The First Hospital of Harbin Medical University, Harbin, China. Electronic address: .
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Źródło :
Gene [Gene] 2020 Mar 01; Vol. 729, pp. 144319. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0038 (Electronic) Linking ISSN: 03781119 NLM ISO Abbreviation: Gene Subsets: MEDLINE
MeSH Terms :
Atherosclerosis/*genetics
Atherosclerosis/*pathology
Foam Cells/*pathology
HSP90 Heat-Shock Proteins/*genetics
Macrophages/*pathology
MicroRNAs/*genetics
3' Untranslated Regions ; Apoptosis/genetics ; Atherosclerosis/metabolism ; Cell Proliferation/genetics ; Foam Cells/metabolism ; Humans ; Inflammation/genetics ; Macrophages/metabolism ; MicroRNAs/metabolism ; NF-kappa B/metabolism ; THP-1 Cells
Czasopismo naukowe
Tytuł :
circRNA/lncRNA-miRNA-mRNA Network in Oxidized, Low-Density, Lipoprotein-Induced Foam Cells.
Autorzy :
Wang L; Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Zheng Z; Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Feng X; Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Zang X; Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Ding W; Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Wu F; Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Zhao Q; Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, China.; Jilin Provincial Key Laboratory for Genetic Diagnosis of Cardiovascular Disease, China-Japan Union Hospital of Jilin University, Changchun, China.; Jilin Provincial Engineering Laboratory for Endothelial Function and Genetic Diagnosis of Cardiovascular Disease, China-Japan Union Hospital of Jilin University, Changchun, China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2019 Dec; Vol. 38 (12), pp. 1499-1511.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 9004522 Publication Model: Print Cited Medium: Internet ISSN: 1557-7430 (Electronic) Linking ISSN: 10445498 NLM ISO Abbreviation: DNA Cell Biol. Subsets: MEDLINE
MeSH Terms :
Foam Cells/*metabolism
Lipoproteins, LDL/*administration & dosage
Macrophages/*metabolism
MicroRNAs/*genetics
RNA, Circular/*genetics
RNA, Long Noncoding/*genetics
RNA, Messenger/*genetics
Cells, Cultured ; Foam Cells/cytology ; Foam Cells/drug effects ; Gene Expression Regulation/drug effects ; Gene Regulatory Networks ; Humans ; Macrophages/cytology ; Macrophages/drug effects ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
CCAAT/enhancer-binding protein beta (C/EBPβ) knockdown reduces inflammation, ER stress, and apoptosis, and promotes autophagy in oxLDL-treated RAW264.7 macrophage cells.
Autorzy :
Zahid MDK; Department of Nutritional Sciences & Obesity Research Institute, Texas Tech University, Lubbock, TX, 79409-1270, USA.
Rogowski M; Department of Nutritional Sciences & Obesity Research Institute, Texas Tech University, Lubbock, TX, 79409-1270, USA.
Ponce C; Department of Mathematics, Texas Tech University, Lubbock, TX, 79409-1270, USA.
Choudhury M; Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M, Health Sciences Center, College Station, TX, 78363, USA.
Moustaid-Moussa N; Department of Nutritional Sciences & Obesity Research Institute, Texas Tech University, Lubbock, TX, 79409-1270, USA.
Rahman SM; Department of Nutritional Sciences & Obesity Research Institute, Texas Tech University, Lubbock, TX, 79409-1270, USA. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2020 Jan; Vol. 463 (1-2), pp. 211-223. Date of Electronic Publication: 2019 Nov 04.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol. Cell. Biochem. Subsets: MEDLINE
MeSH Terms :
Apoptosis*
Endoplasmic Reticulum Stress*
Gene Expression Regulation*
CCAAT-Enhancer-Binding Protein-beta/*metabolism
Foam Cells/*metabolism
Lipoproteins, LDL/*metabolism
Animals ; CCAAT-Enhancer-Binding Protein-beta/genetics ; Foam Cells/pathology ; Gene Knockdown Techniques ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Lipoproteins, LDL/genetics ; Mice ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism of LDL (Low-Density Lipoprotein) Aggregates.
Autorzy :
Singh RK; From the Department of Biochemistry, Weill Cornell Medical College, New York, NY (R.K.S., A.S.H., A.A., V.C.B.-L., I.G., H.F.C., F.R.M.).
Haka AS; From the Department of Biochemistry, Weill Cornell Medical College, New York, NY (R.K.S., A.S.H., A.A., V.C.B.-L., I.G., H.F.C., F.R.M.).
Asmal A; From the Department of Biochemistry, Weill Cornell Medical College, New York, NY (R.K.S., A.S.H., A.A., V.C.B.-L., I.G., H.F.C., F.R.M.).
Barbosa-Lorenzi VC; From the Department of Biochemistry, Weill Cornell Medical College, New York, NY (R.K.S., A.S.H., A.A., V.C.B.-L., I.G., H.F.C., F.R.M.).
Grosheva I; From the Department of Biochemistry, Weill Cornell Medical College, New York, NY (R.K.S., A.S.H., A.A., V.C.B.-L., I.G., H.F.C., F.R.M.).
Chin HF; From the Department of Biochemistry, Weill Cornell Medical College, New York, NY (R.K.S., A.S.H., A.A., V.C.B.-L., I.G., H.F.C., F.R.M.).
Xiong Y; Vascular Biology Program, Boston Children's Hospital and Department of Surgery, Harvard Medical School, Boston, MA (Y.X., T.H.).; Current address: Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY (Y.X.).
Hla T; Vascular Biology Program, Boston Children's Hospital and Department of Surgery, Harvard Medical School, Boston, MA (Y.X., T.H.).
Maxfield FR; From the Department of Biochemistry, Weill Cornell Medical College, New York, NY (R.K.S., A.S.H., A.A., V.C.B.-L., I.G., H.F.C., F.R.M.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Jan; Vol. 40 (1), pp. 86-102. Date of Electronic Publication: 2019 Oct 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler. Thromb. Vasc. Biol. Subsets: MEDLINE
MeSH Terms :
Aorta, Thoracic/*metabolism
Atherosclerosis/*metabolism
Extracellular Fluid/*metabolism
Foam Cells/*metabolism
Lipoproteins, LDL/*metabolism
Toll-Like Receptor 4/*metabolism
Animals ; Aorta, Thoracic/pathology ; Atherosclerosis/pathology ; Cells, Cultured ; Disease Models, Animal ; Female ; Flow Cytometry ; Foam Cells/pathology ; Immunoblotting ; Mice ; Mice, Knockout ; Signal Transduction
Czasopismo naukowe
Tytuł :
Quercetin Suppresses the Progression of Atherosclerosis by Regulating MST1-Mediated Autophagy in ox-LDL-Induced RAW264.7 Macrophage Foam Cells.
Autorzy :
Cao H; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365C Xiangyang South Road, Xuhui, Shanghai 200031, China.
Jia Q; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365C Xiangyang South Road, Xuhui, Shanghai 200031, China.
Yan L; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365C Xiangyang South Road, Xuhui, Shanghai 200031, China.
Chen C; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365C Xiangyang South Road, Xuhui, Shanghai 200031, China.
Xing S; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365C Xiangyang South Road, Xuhui, Shanghai 200031, China.
Shen D; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 365C Xiangyang South Road, Xuhui, Shanghai 200031, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Dec 03; Vol. 20 (23). Date of Electronic Publication: 2019 Dec 03.
Typ publikacji :
Journal Article
Journal Info :
Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
MeSH Terms :
Disease Progression*
Atherosclerosis/*pathology
Autophagy/*drug effects
Foam Cells/*metabolism
Foam Cells/*pathology
Hepatocyte Growth Factor/*metabolism
Lipoproteins, LDL/*pharmacology
Proto-Oncogene Proteins/*metabolism
Quercetin/*pharmacology
Adenine/analogs & derivatives ; Adenine/pharmacology ; Animals ; Cell Survival/drug effects ; Cellular Senescence/drug effects ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Foam Cells/drug effects ; Lipid Metabolism/drug effects ; Mice ; RAW 264.7 Cells ; Sirolimus/pharmacology ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Geniposide against atherosclerosis by inhibiting the formation of foam cell and lowering reverse lipid transport via p38/MAPK signaling pathways.
Autorzy :
Shen D; College of Pharmacy, Institute of Life Science, Chongqing Medical University, Chongqing, 400016, PR China; Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing, 400016, PR China.
Zhao D; College of Pharmacy, Institute of Life Science, Chongqing Medical University, Chongqing, 400016, PR China.
Yang X; College of Pharmacy, Institute of Life Science, Chongqing Medical University, Chongqing, 400016, PR China.
Zhang J; College of Pharmacy, Institute of Life Science, Chongqing Medical University, Chongqing, 400016, PR China.
He H; College of Pharmacy, Institute of Life Science, Chongqing Medical University, Chongqing, 400016, PR China; Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing, 400016, PR China.
Yu C; College of Pharmacy, Institute of Life Science, Chongqing Medical University, Chongqing, 400016, PR China; Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing, 400016, PR China; Chongqing pharmacodynamic evaluation engineering technology research center, Chongqing, 400016, PR China. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2019 Dec 01; Vol. 864, pp. 172728. Date of Electronic Publication: 2019 Oct 07.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur. J. Pharmacol. Subsets: MEDLINE
MeSH Terms :
Atherosclerosis/*drug therapy
Foam Cells/*drug effects
Iridoids/*pharmacology
Lipid Metabolism/*drug effects
MAP Kinase Signaling System/*drug effects
p38 Mitogen-Activated Protein Kinases/*metabolism
ATP Binding Cassette Transporter 1/metabolism ; Animals ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Biological Transport/drug effects ; CD36 Antigens/metabolism ; Dose-Response Relationship, Drug ; Down-Regulation/drug effects ; Foam Cells/pathology ; Iridoids/therapeutic use ; Male ; Mice ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Scavenger Receptors, Class A/metabolism ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Oxygen levels during negative pressure wound therapy.
Autorzy :
Biermann N; Department of Plastic, Hand- and Reconstructive Surgery, University Hospital Regensburg, Germany.
Geissler EK; Department of Surgery, University Hospital Regensburg, Germany.
Brix E; Department of Plastic, Hand- and Reconstructive Surgery, University Hospital Regensburg, Germany.
Schiltz D; Department of Plastic, Hand- and Reconstructive Surgery, University Hospital Regensburg, Germany.
Prantl L; Department of Plastic, Hand- and Reconstructive Surgery, University Hospital Regensburg, Germany.
Kehrer A; Department of Plastic, Hand- and Reconstructive Surgery, University Hospital Regensburg, Germany.
Taeger CD; Department of Plastic, Hand- and Reconstructive Surgery, University Hospital Regensburg, Germany. Electronic address: .
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Źródło :
Journal of tissue viability [J Tissue Viability] 2019 Nov; Vol. 28 (4), pp. 223-226. Date of Electronic Publication: 2019 Sep 04.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Tissue Viability Society Country of Publication: England NLM ID: 9306822 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0965-206X (Print) Linking ISSN: 0965206X NLM ISO Abbreviation: J Tissue Viability Subsets: Nursing
MeSH Terms :
Foam Cells/*metabolism
Negative-Pressure Wound Therapy/*instrumentation
Oxygen/*analysis
Wound Healing/*physiology
Foam Cells/chemistry ; Foam Cells/physiology ; Humans ; Negative-Pressure Wound Therapy/standards ; Negative-Pressure Wound Therapy/statistics & numerical data ; Oxygen/metabolism
Czasopismo naukowe
Tytuł :
MiR-202-3p Inhibits Foam Cell Formation and is Associated with Coronary Heart Disease Risk in a Chinese Population.
Autorzy :
Li L; Research Center of Translational Medicine, The Second Affiliated Hospital of Shantou University Medical College.
Wu F; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University.
Xie Y; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University.
Xu W; Research Center of Translational Medicine, The Second Affiliated Hospital of Shantou University Medical College.
Xiong G; Medical Big Data Research Center, The Second Affiliated Hospital of Nanchang University.
Xu Y; Medical Big Data Research Center, The Second Affiliated Hospital of Nanchang University.
Huang S; Department of Molecular Epidemiology, Shenzhen Center for Disease Control and Prevention.
Wu Y; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University.
Jiang X; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University.
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Źródło :
International heart journal [Int Heart J] 2020 Jan 31; Vol. 61 (1), pp. 153-159. Date of Electronic Publication: 2020 Jan 17.
Typ publikacji :
Journal Article
Journal Info :
Publisher: International Heart Journal Association Country of Publication: Japan NLM ID: 101244240 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-3299 (Electronic) Linking ISSN: 13492365 NLM ISO Abbreviation: Int Heart J Subsets: MEDLINE
MeSH Terms :
Asian Continental Ancestry Group/*genetics
Coronary Disease/*genetics
Foam Cells/*cytology
MicroRNAs/*genetics
Aged ; Case-Control Studies ; Cells, Cultured ; Female ; Foam Cells/metabolism ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Lipoproteins, LDL/metabolism ; Macrophages/cytology ; Macrophages/metabolism ; Male ; Middle Aged ; THP-1 Cells ; Up-Regulation
Czasopismo naukowe
Tytuł :
Fisetin, via CKIP-1/REGγ, limits oxidized LDL-induced lipid accumulation and senescence in RAW264.7 macrophage-derived foam cells.
Autorzy :
Jia Q; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200031, China.
Cao H; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200031, China.
Shen D; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200031, China. Electronic address: .
Yan L; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200031, China.
Chen C; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200031, China.
Xing S; Shanghai Geriatric Institute of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200031, China.
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2019 Dec 15; Vol. 865, pp. 172748. Date of Electronic Publication: 2019 Oct 23.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur. J. Pharmacol. Subsets: MEDLINE
MeSH Terms :
Autoantigens/*metabolism
Carrier Proteins/*metabolism
Flavonoids/*pharmacology
Foam Cells/*drug effects
Lipoproteins, LDL/*metabolism
Proteasome Endopeptidase Complex/*metabolism
Animals ; Cellular Senescence/drug effects ; Foam Cells/metabolism ; Lipid Metabolism/drug effects ; Mice ; RAW 264.7 Cells ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NFκB-mediated NLRP3 upregulation.
Autorzy :
Zang YH; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Chen D; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Zhou B; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Chen AD; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Wang JJ; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Gao XY; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Chen Q; Department of Pathophysiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Li YH; Department of Pathophysiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
Kang YM; Department of Physiology and Pathophysiology, Cardiovascular Research Center, Xi'an Jiaotong University School of Medicine, Xi'an 710061, China.
Zhu GQ; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, Department of Physiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China; Department of Pathophysiology, Nanjing Medical University, Nanjing, Jiangsu 211166, China. Electronic address: .
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Źródło :
Vascular pharmacology [Vascul Pharmacol] 2019 Oct; Vol. 121, pp. 106579. Date of Electronic Publication: 2019 Jul 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3649 (Electronic) Linking ISSN: 15371891 NLM ISO Abbreviation: Vascul. Pharmacol. Subsets: MEDLINE
MeSH Terms :
Cell Adhesion/*drug effects
Fibronectins/*metabolism
Foam Cells/*drug effects
Lipoproteins, LDL/*pharmacology
Monocytes/*drug effects
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
NF-kappa B/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Animals ; Fibronectins/genetics ; Fibronectins/pharmacology ; Foam Cells/metabolism ; Foam Cells/pathology ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Monocytes/metabolism ; Monocytes/pathology ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Signal Transduction ; THP-1 Cells ; Up-Regulation
Czasopismo naukowe
Tytuł :
Oligomeric proanthocyanidins and epigallocatechin gallate aggravate autophagy of foam cells through the activation of Class III PI3K/Beclin1-complex mediated cholesterol efflux.
Autorzy :
Jamuna S; Department of Biochemistry, University of Madras, Chennai, Tamil Nadu, India.
Ashokkumar R; Department of Biochemistry, University of Madras, Chennai, Tamil Nadu, India.
Sakeena Sadullah MS; Department of Biochemistry, University of Madras, Chennai, Tamil Nadu, India.
Devaraj SN; Department of Biochemistry, University of Madras, Chennai, Tamil Nadu, India.
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Źródło :
BioFactors (Oxford, England) [Biofactors] 2019 Sep; Vol. 45 (5), pp. 763-773. Date of Electronic Publication: 2019 Jun 25.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Ios Press Country of Publication: Netherlands NLM ID: 8807441 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8081 (Electronic) Linking ISSN: 09516433 NLM ISO Abbreviation: Biofactors Subsets: MEDLINE
MeSH Terms :
Beclin-1/*genetics
Catechin/*analogs & derivatives
Cholesterol/*metabolism
Class III Phosphatidylinositol 3-Kinases/*genetics
Foam Cells/*drug effects
Proanthocyanidins/*pharmacology
ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter 1/metabolism ; Autophagy/drug effects ; Autophagy/genetics ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 5/metabolism ; Beclin-1/metabolism ; Catechin/pharmacology ; Chromones/pharmacology ; Class III Phosphatidylinositol 3-Kinases/antagonists & inhibitors ; Class III Phosphatidylinositol 3-Kinases/metabolism ; Enzyme Inhibitors/pharmacology ; Foam Cells/cytology ; Foam Cells/metabolism ; Gene Expression Regulation ; Humans ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism ; Morpholines/pharmacology ; Phagosomes/drug effects ; Phagosomes/metabolism ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; THP-1 Cells ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Giant cells lepromatous leprosy. Diffuse dermatitis with exuberant foreign body giant cells in treated lepromatous leprosy
Transliterated Title :
Células gigantes en lepra lepromatosa. Dermatitis difusa con células gigantes tipo cuerpo extraño exuberantes en lepra lepromatosa tratada
Autorzy :
Rodríguez G; Facultad de Medicina, Universidad de La Sabana, Chía, Colombia; Hospital Centro Dermatológico Federico Lleras Acosta, Bogotá, D.C., Colombia. .
Arias V
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Źródło :
Biomedica : revista del Instituto Nacional de Salud [Biomedica] 2019 Aug 01; Vol. 39 (Supl. 2), pp. 26-31. Date of Electronic Publication: 2019 Aug 01.
Typ publikacji :
Case Reports; Journal Article
Journal Info :
Publisher: Instituto Nacional de Salud Country of Publication: Colombia NLM ID: 8205605 Publication Model: Electronic Cited Medium: Internet ISSN: 0120-4157 (Print) Linking ISSN: 01204157 NLM ISO Abbreviation: Biomedica Subsets: MEDLINE
MeSH Terms :
Foam Cells/*pathology
Giant Cells, Foreign-Body/*pathology
Leprosy, Lepromatous/*pathology
Skin/*pathology
Antigens, CD/analysis ; Antigens, Differentiation, Myelomonocytic/analysis ; Biopsy ; Cell Wall/chemistry ; Drug Therapy, Combination ; Female ; Foam Cells/chemistry ; Foam Cells/microbiology ; Giant Cells, Foreign-Body/chemistry ; Giant Cells, Foreign-Body/microbiology ; Host-Pathogen Interactions ; Humans ; Leprostatic Agents/therapeutic use ; Leprosy, Lepromatous/drug therapy ; Lipids/analysis ; Middle Aged ; Mycobacterium leprae/chemistry ; Mycobacterium leprae/isolation & purification ; Skin/microbiology ; Vacuoles
Czasopismo naukowe

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