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Tytuł:
The effects of glycosylation modifications on monocyte recruitment and foam cell formation in atherosclerosis.
Autorzy:
Teng D; Yantai Yuhuangding Hospital affiliated to Qingdao University, Yantai, Shandong, People's Republic of China; Qingdao University, Qingdao, Shandong, People's Republic of China.
Wang W; Yantai Yuhuangding Hospital affiliated to Qingdao University, Yantai, Shandong, People's Republic of China; Qingdao University, Qingdao, Shandong, People's Republic of China.
Jia W; Yantai Yuhuangding Hospital affiliated to Qingdao University, Yantai, Shandong, People's Republic of China; Qingdao University, Qingdao, Shandong, People's Republic of China.
Song J; Yantai Yuhuangding Hospital affiliated to Qingdao University, Yantai, Shandong, People's Republic of China; Qingdao University, Qingdao, Shandong, People's Republic of China.
Gong L; Yantai Yuhuangding Hospital affiliated to Qingdao University, Yantai, Shandong, People's Republic of China.
Zhong L; Yantai Yuhuangding Hospital affiliated to Qingdao University, Yantai, Shandong, People's Republic of China. Electronic address: .
Yang J; Yantai Yuhuangding Hospital affiliated to Qingdao University, Yantai, Shandong, People's Republic of China; Qingdao University, Qingdao, Shandong, People's Republic of China. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Mar; Vol. 1870 (3), pp. 167027. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Foam Cells*
Atherosclerosis*/metabolism
Humans ; Monocytes/metabolism ; Glycosylation ; Macrophages/metabolism
Czasopismo naukowe
Tytuł:
Proteomic analysis reveals the mechanisms of the astaxanthin suppressed foam cell formation.
Autorzy:
Liu A; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Laboratory for Cereal Fermentation Technology, Collaborative Innovation Center of Food Safety and Quality Control, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China.
Li R; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Laboratory for Cereal Fermentation Technology, Collaborative Innovation Center of Food Safety and Quality Control, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China.
Zaaboul F; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Laboratory for Cereal Fermentation Technology, Collaborative Innovation Center of Food Safety and Quality Control, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China.
He M; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Laboratory for Cereal Fermentation Technology, Collaborative Innovation Center of Food Safety and Quality Control, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China.
Li X; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Laboratory for Cereal Fermentation Technology, Collaborative Innovation Center of Food Safety and Quality Control, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China.
Shi J; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Laboratory for Cereal Fermentation Technology, Collaborative Innovation Center of Food Safety and Quality Control, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China.
Liu Y; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Laboratory for Cereal Fermentation Technology, Collaborative Innovation Center of Food Safety and Quality Control, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China. Electronic address: .
Xu YJ; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Laboratory for Cereal Fermentation Technology, Collaborative Innovation Center of Food Safety and Quality Control, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2023 Jul 15; Vol. 325, pp. 121774. Date of Electronic Publication: 2023 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
Foam Cells*/metabolism
Atherosclerosis*/drug therapy
Atherosclerosis*/metabolism
Humans ; Proteomics ; Cholesterol/metabolism ; Lipoproteins, LDL/metabolism ; Proteins/metabolism ; Phosphatidylinositol 3-Kinases/metabolism
Czasopismo naukowe
Tytuł:
The atheroprotective role of fucoidan involves the reduction of foam cell formation by altering cholesterol flux-associated factors in macrophages.
Autorzy:
Fernandes-Braga W; Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
Aguilar EC; Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
Navia-Pelaez JM; Department of Medicine, University of California San Diego, San Diego, United States. Electronic address: .
Ávila DL; Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
Rezende L; Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
Andrade LO; Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
Miranda SEM; Department of Clinical and Toxicological Analysis, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
Barros ALB; Department of Clinical and Toxicological Analysis, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
Capettini LDSA; Department of Pharmacology, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
Alvarez-Leite JI; Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Apr 02; Vol. 650, pp. 21-29. Date of Electronic Publication: 2023 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Foam Cells*/metabolism
Atherosclerosis*/metabolism
Mice ; Animals ; Tissue Distribution ; Mice, Knockout, ApoE ; Macrophages/metabolism ; Cholesterol/metabolism ; Lipoproteins, LDL/metabolism ; Polysaccharides/metabolism ; Receptors, Scavenger/metabolism ; Apolipoproteins E/metabolism
Czasopismo naukowe
Tytuł:
The healing effects of L-carnitine and spongostan on cartilage defect in rat model.
Autorzy:
Ok MU; Department of Orthopaedia and Traumatology, Bismil State Hospital, Diyarbakir, Turkey.
Şahin R; Department of Orthopaedia and Traumatology, Faculty of Medicine, Recep Tayyip Erdogan University, Rize, Turkey. Electronic address: .
Balik MS; Department of Orthopaedia and Traumatology, Faculty of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.
Okçu O; Department of Pathology, Faculty of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.
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Źródło:
Injury [Injury] 2023 Dec; Vol. 54 (12), pp. 111115. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cartilage, Articular*/pathology
Cartilage Diseases*
Rats ; Animals ; Fibrin Foam/pharmacology ; Rats, Sprague-Dawley ; Carnitine/pharmacology ; Adenosine Triphosphate/pharmacology
Czasopismo naukowe
Tytuł:
Angiotensin II induces the expression of periostin to promote foam cell formation in oxLDL-treated macrophages.
Autorzy:
Gao F; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Bai R; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Qin W; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Liang B; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Yang Z; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Yang H; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China. Electronic address: .
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Źródło:
International journal of cardiology [Int J Cardiol] 2022 Jan 15; Vol. 347, pp. 46-53. Date of Electronic Publication: 2021 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin II*
Foam Cells*
Cell Adhesion Molecules ; Cholesterol ; Humans ; Lipoproteins, LDL ; Macrophages
Czasopismo naukowe
Tytuł:
Diverse diterpenoids from Callicarpa rubella Lindl. as natural inhibitors of macrophage foam cell formation.
Autorzy:
Wu XW; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
Feng QL; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
Xie YF; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
Song SC; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
Cheng B; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
Ma Y; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
Li Q; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
Ji X; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
Li XL; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China; State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, PR China. Electronic address: .
Cao G; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China. Electronic address: .
Xiao WL; Key Laboratory of Medicinal Chemistry for Natural Resource of Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Research & Development Center for Natural Products, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China; State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, PR China. Electronic address: .
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Źródło:
Phytochemistry [Phytochemistry] 2023 Sep; Vol. 213, pp. 113748. Date of Electronic Publication: 2023 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Callicarpa*/chemistry
Diterpenes*/chemistry
Rubella*/metabolism
Abietanes/chemistry ; Foam Cells ; Molecular Structure ; Plant Leaves/chemistry ; Macrophages
Czasopismo naukowe
Tytuł:
Activin a inhibits foam cell formation and up-regulates ABCA1 and ABCG1 expression through Alk4-Smad signaling pathway in RAW 264.7 macrophages.
Autorzy:
Wang H; Department of Geriatrics, Peking University First Hospital, Beijing 100034, People's Republic of China.
Zhang P; Department of Geriatrics, Peking University First Hospital, Beijing 100034, People's Republic of China; Division of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen 361000, People's Republic of China.
Chen X; Department of Geriatrics, Peking University First Hospital, Beijing 100034, People's Republic of China.
Liu W; Department of Geriatrics, Peking University First Hospital, Beijing 100034, People's Republic of China.
Fu Z; Department of Geriatrics, Peking University First Hospital, Beijing 100034, People's Republic of China.
Liu M; Department of Geriatrics, Peking University First Hospital, Beijing 100034, People's Republic of China. Electronic address: .
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Źródło:
Steroids [Steroids] 2021 Oct; Vol. 174, pp. 108887. Date of Electronic Publication: 2021 Jul 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Foam Cells*
Czasopismo naukowe
Tytuł:
Foam cell formation but not oxLDL cytotoxicity is inhibited by CD36 down regulation by the macrophage antioxidant 7,8-dihydroneopterin.
Autorzy:
Ghodsian N; Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand.
Yeandle A; Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand.
Gieseg SP; Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand; Department of Radiology, University of Otago, Christchurch, New Zealand. Electronic address: .
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Źródło:
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2021 Apr; Vol. 133, pp. 105918. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antioxidants/*pharmacology
CD36 Antigens/*antagonists & inhibitors
Foam Cells/*drug effects
Lipoproteins, LDL/*adverse effects
Macrophages/*metabolism
Neopterin/*analogs & derivatives
Plaque, Atherosclerotic/*drug therapy
Cell Differentiation ; Down-Regulation ; Foam Cells/metabolism ; Foam Cells/pathology ; Humans ; Neopterin/pharmacology ; Plaque, Atherosclerotic/metabolism ; Plaque, Atherosclerotic/pathology ; U937 Cells
Czasopismo naukowe
Tytuł:
Ganoderma lucidum triterpenoids and polysaccharides attenuate atherosclerotic plaque in high-fat diet rabbits.
Autorzy:
Li Y; Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Institute of Medical Laboratory Animal Science, CAMS & PUMC, Key Laboratory of Human Diseases Animal Models, State Administration of Traditional Chinese Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Beijing, 100021, China.
Tang J; Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Institute of Medical Laboratory Animal Science, CAMS & PUMC, Key Laboratory of Human Diseases Animal Models, State Administration of Traditional Chinese Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Beijing, 100021, China.
Gao H; Department of Pathology, Qinghai Provincial People's Hospital, Qinghai, 810007, China.
Xu Y; Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Institute of Medical Laboratory Animal Science, CAMS & PUMC, Key Laboratory of Human Diseases Animal Models, State Administration of Traditional Chinese Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Beijing, 100021, China.
Han Y; Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Institute of Medical Laboratory Animal Science, CAMS & PUMC, Key Laboratory of Human Diseases Animal Models, State Administration of Traditional Chinese Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Beijing, 100021, China.
Shang H; Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Institute of Medical Laboratory Animal Science, CAMS & PUMC, Key Laboratory of Human Diseases Animal Models, State Administration of Traditional Chinese Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Beijing, 100021, China.
Lu Y; Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Institute of Medical Laboratory Animal Science, CAMS & PUMC, Key Laboratory of Human Diseases Animal Models, State Administration of Traditional Chinese Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Beijing, 100021, China.
Qin C; Key Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Institute of Medical Laboratory Animal Science, CAMS & PUMC, Key Laboratory of Human Diseases Animal Models, State Administration of Traditional Chinese Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Beijing, 100021, China. Electronic address: .
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Źródło:
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2021 Jun 07; Vol. 31 (6), pp. 1929-1938. Date of Electronic Publication: 2021 Apr 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Plaque, Atherosclerotic*
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Aorta/*drug effects
Aortic Diseases/*prevention & control
Atherosclerosis/*prevention & control
Foam Cells/*drug effects
Polysaccharides/*pharmacology
Triterpenes/*pharmacology
Animals ; Anti-Inflammatory Agents/isolation & purification ; Antioxidants/isolation & purification ; Aorta/metabolism ; Aorta/pathology ; Aortic Diseases/metabolism ; Aortic Diseases/pathology ; Apoptosis/drug effects ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Cell Proliferation/drug effects ; Cytokines/metabolism ; Diet, High-Fat ; Disease Models, Animal ; Female ; Foam Cells/metabolism ; Foam Cells/pathology ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells/pathology ; Humans ; Inflammation Mediators/metabolism ; Male ; Oxidative Stress/drug effects ; Polysaccharides/isolation & purification ; Rabbits ; Reactive Oxygen Species/metabolism ; Reishi/chemistry ; THP-1 Cells ; Triterpenes/isolation & purification
Czasopismo naukowe
Tytuł:
Oxidized low-density lipoprotein induced hepatoma-derived growth factor upregulation mediates foam cell formation of cultured rat aortic vascular smooth muscle cells.
Autorzy:
Cheng CI; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang-Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address: .
Tai MH; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.
Chang HR; Department of Biomedical Engineering, I-Shou University, Kaohsiung, Taiwan.
Chou MH; Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Kaohsiung, Taiwan; Center for General Education, Cheng-Shiu University, Kaohsiung, Taiwan.
Chen GT; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang-Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Chen PH; Department of Medical Research, E-Da Hospital, Kaohsiung, Taiwan.
Kao YH; Department of Medical Research, E-Da Hospital, Kaohsiung, Taiwan. Electronic address: .
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Źródło:
European journal of cell biology [Eur J Cell Biol] 2021 Jun-Aug; Vol. 100 (5-6), pp. 151169. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji:
Journal Article
MeSH Terms:
Foam Cells*/metabolism
Muscle, Smooth, Vascular*
Animals ; Cells, Cultured ; Intercellular Signaling Peptides and Proteins ; Lipoproteins, LDL/metabolism ; Phosphatidylinositol 3-Kinases ; Rats ; Up-Regulation
Czasopismo naukowe
Tytuł:
The vitamin E long-chain metabolite α-13'-COOH affects macrophage foam cell formation via modulation of the lipoprotein lipase system.
Autorzy:
Kluge S; Institute of Nutritional Sciences, Friedrich Schiller University, Jena, Germany.
Schubert M; Institute of Nutritional Sciences, Friedrich Schiller University, Jena, Germany.
Börmel L; Institute of Nutritional Sciences, Friedrich Schiller University, Jena, Germany.
Lorkowski S; Institute of Nutritional Sciences, Friedrich Schiller University, Jena, Germany; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Germany. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Apr; Vol. 1866 (4), pp. 158875. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Benzopyrans/*metabolism
Fatty Acids/*metabolism
Foam Cells/*metabolism
Lipoprotein Lipase/*metabolism
Macrophages/*metabolism
Vitamin E/*metabolism
Cell Line ; Down-Regulation ; Foam Cells/cytology ; Humans ; Lipoprotein Lipase/genetics ; Macrophages/cytology ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Plasminogen-induced foam cell formation by macrophages occurs through a histone 2B (H2B)-PAR1 pathway and requires integrity of clathrin-coated pits.
Autorzy:
Izem L; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute Cleveland Clinic, Cleveland, Ohio, USA.
Bialkowska K; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute Cleveland Clinic, Cleveland, Ohio, USA.
Pluskota E; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute Cleveland Clinic, Cleveland, Ohio, USA.
Das M; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute Cleveland Clinic, Cleveland, Ohio, USA.
Das R; Roberts J. Tomsich Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Nieman MT; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA.
Plow EF; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute Cleveland Clinic, Cleveland, Ohio, USA.
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Źródło:
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Apr; Vol. 19 (4), pp. 941-953. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Foam Cells*/metabolism
Plasminogen*/metabolism
Animals ; Clathrin/metabolism ; Fibrinolysin/metabolism ; Histones ; Macrophages/metabolism ; Mice ; Receptor, PAR-1
Czasopismo naukowe
Tytuł:
Decidua basalis and acute atherosis: Expression of atherosclerotic foam cell associated proteins.
Autorzy:
Fosheim IK; Division of Obstetrics and Gynecology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.
Johnsen GM; Division of Obstetrics and Gynecology, Oslo University Hospital, Oslo, Norway.
Alnaes-Katjavivi P; Division of Obstetrics and Gynecology, Oslo University Hospital, Oslo, Norway.
Turowski G; Department of Pathology, Oslo University Hospital, Oslo, Norway.
Sugulle M; Division of Obstetrics and Gynecology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.
Staff AC; Division of Obstetrics and Gynecology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway. Electronic address: .
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Źródło:
Placenta [Placenta] 2021 Apr; Vol. 107, pp. 1-7. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis/*metabolism
Decidua/*metabolism
Fatty Acid-Binding Proteins/*metabolism
Foam Cells/*metabolism
Perilipin-2/*metabolism
Scavenger Receptors, Class E/*metabolism
Adult ; Atherosclerosis/pathology ; Decidua/pathology ; Female ; Foam Cells/pathology ; Humans
Czasopismo naukowe
Tytuł:
Effect of oxytocin on lipid accumulation under inflammatory conditions in human macrophages.
Autorzy:
Karten A; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America.
Vernice NA; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America.
Renna HA; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America.
Carsons SE; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America.
DeLeon J; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America.
Pinkhasov A; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America.
Gomolin IH; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America.
Glass DS; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America.
Reiss AB; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America.
Kasselman LJ; NYU Langone Hospital - Long Island Biomedical Research Institute and NYU Long Island School of Medicine, Mineola, New York, United States of America. Electronic address: .
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Źródło:
Experimental and molecular pathology [Exp Mol Pathol] 2021 Feb; Vol. 118, pp. 104604. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis/*drug therapy
Cholesterol/*metabolism
Foam Cells/*drug effects
Inflammation/*drug therapy
Macrophages/*drug effects
Oxytocin/*pharmacology
Plaque, Atherosclerotic/*drug therapy
ATP Binding Cassette Transporter, Subfamily G, Member 1/metabolism ; Atherosclerosis/chemically induced ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Cells, Cultured ; Foam Cells/metabolism ; Foam Cells/pathology ; Humans ; Inflammation/chemically induced ; Inflammation/metabolism ; Inflammation/pathology ; Lipopolysaccharides/toxicity ; Macrophages/metabolism ; Macrophages/pathology ; Oxytocics/pharmacology ; Plaque, Atherosclerotic/chemically induced ; Plaque, Atherosclerotic/metabolism ; Plaque, Atherosclerotic/pathology ; Receptors, Oxytocin/metabolism
Czasopismo naukowe
Tytuł:
SIRT1-autophagy axis inhibits excess iron-induced ferroptosis of foam cells and subsequently increases IL-1Β and IL-18.
Autorzy:
Su G; Department of Laboratory Diagnostics, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, NanGang, Harbin, Heilongjiang, 150001, PR China. Electronic address: .
Yang W; Department of Laboratory Diagnostics, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, NanGang, Harbin, Heilongjiang, 150001, PR China. Electronic address: .
Wang S; Department of Laboratory Diagnostics, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, NanGang, Harbin, Heilongjiang, 150001, PR China. Electronic address: .
Geng C; Department of Laboratory Diagnostics, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, NanGang, Harbin, Heilongjiang, 150001, PR China. Electronic address: .
Guan X; Department of Laboratory Diagnostics, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, NanGang, Harbin, Heilongjiang, 150001, PR China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jul 05; Vol. 561, pp. 33-39. Date of Electronic Publication: 2021 May 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis/*pathology
Foam Cells/*pathology
Interleukin-18/*metabolism
Interleukin-1beta/*metabolism
Iron Overload/*pathology
Sirtuin 1/*metabolism
Animals ; Atherosclerosis/metabolism ; Autophagy/physiology ; Cells, Cultured ; Disease Models, Animal ; Ferroptosis/physiology ; Foam Cells/metabolism ; Humans ; Interleukin-18/genetics ; Interleukin-1beta/genetics ; Iron Overload/metabolism ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Mice ; Mice, Knockout, ApoE ; Signal Transduction ; Sirtuin 1/genetics
Czasopismo naukowe
Tytuł:
A CD36 transmembrane domain peptide interrupts CD36 interactions with membrane partners on macrophages and inhibits atherogenic functions.
Autorzy:
Huang W; Laboratory of Vascular Pathobiology, Versiti Blood Center of Wisconsin, Blood Research Institute, Milwaukee, Wisconsin.
Li R; Department of Pediatrics, Division of Hematology/Oncology, Emory University School of Medicine, Atlanta, Georgia.
Zhang J; Laboratory of Vascular Pathobiology, Versiti Blood Center of Wisconsin, Blood Research Institute, Milwaukee, Wisconsin.
Cheng Y; Laboratory of Vascular Pathobiology, Versiti Blood Center of Wisconsin, Blood Research Institute, Milwaukee, Wisconsin; Department of Medicine, Medical Colleges of Wisconsin, Milwaukee, Wisconsin; Department of Biochemistry, Medical Colleges of Wisconsin, Milwaukee, Wisconsin.
Ramakrishnan DP; Laboratory of Vascular Pathobiology, Versiti Blood Center of Wisconsin, Blood Research Institute, Milwaukee, Wisconsin.
Silverstein RL; Laboratory of Vascular Pathobiology, Versiti Blood Center of Wisconsin, Blood Research Institute, Milwaukee, Wisconsin; Department of Medicine, Medical Colleges of Wisconsin, Milwaukee, Wisconsin. Electronic address: .
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Źródło:
Translational research : the journal of laboratory and clinical medicine [Transl Res] 2023 Apr; Vol. 254, pp. 68-76. Date of Electronic Publication: 2022 Nov 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis*/metabolism
Macrophages*/metabolism
Animals ; Mice ; CD36 Antigens/metabolism ; Foam Cells/metabolism ; Membrane Proteins ; Peptides ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
An advanced method for quantitative measurements of cholesterol crystallization.
Autorzy:
Halkias C; School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australia.
Orth A; ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP), School of Science, RMIT University, Melbourne, Victoria 3001, Australia; National Research Council of Canada, Ottawa, Canada.
Feltis BN; School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australia.
Macrides TA; School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australia.
Gibson BC; ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP), School of Science, RMIT University, Melbourne, Victoria 3001, Australia.
Wright PFA; School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australia. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Mar; Vol. 1866 (3), pp. 158872. Date of Electronic Publication: 2020 Dec 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholesterol/*metabolism
Foam Cells/*cytology
Monocytes/*cytology
Plaque, Atherosclerotic/*metabolism
Cholesterol/chemistry ; Crystallization ; Foam Cells/metabolism ; Foam Cells/ultrastructure ; Humans ; Microscopy, Polarization ; Monocytes/metabolism ; Monocytes/ultrastructure ; THP-1 Cells
Czasopismo naukowe
Tytuł:
Pro-inflammatory molecules induce cholesterol accumulation in macrophages: Role of inflammatory response in foam cell formation.
Autorzy:
Orekhov AN; Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 8 Baltiiskaya Street, Moscow, 125315, Russian Federation; Laboratory of Cellular and Molecular Pathology of Cardiovascular System, Institute of Human Morphology, 3 Tsyurupa Street, Moscow, 117418, Russian Federation. Electronic address: .
Markin AM; Laboratory of Cellular and Molecular Pathology of Cardiovascular System, Institute of Human Morphology, 3 Tsyurupa Street, Moscow, 117418, Russian Federation.
Sukhorukov VN; Laboratory of Cellular and Molecular Pathology of Cardiovascular System, Institute of Human Morphology, 3 Tsyurupa Street, Moscow, 117418, Russian Federation.
Khotina VA; Laboratory of Cellular and Molecular Pathology of Cardiovascular System, Institute of Human Morphology, 3 Tsyurupa Street, Moscow, 117418, Russian Federation.
Ivanova E; Institute for Atherosclerosis Research, Skolkovo Innovative Center, Osennyaya Street 4-1-7, Moscow, 121609, Russian Federation. Electronic address: .
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Źródło:
Atherosclerosis [Atherosclerosis] 2021 Mar; Vol. 320, pp. 129-130. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji:
Letter; Comment
MeSH Terms:
Atherosclerosis*
Foam Cells*
Cholesterol ; Humans ; Macrophages
Opinia redakcyjna
Tytuł:
Gypenoside inhibits ox-LDL uptake and foam cell formation through enhancing Sirt1-FOXO1 mediated autophagy flux restoration.
Autorzy:
Hui B; Department of Cardiology, Qingdao Municipal Hospital of Qingdao University, Qingdao, 266071, China.
Hou X; School of Medicine, the University of Missouri, Columbia, MO 65201, USA.
Liu R; Department of Cardiovascular Diseases, Tongji Hospital of Tongji University, Shanghai 200065, China.
Liu XH; Cardiovascular Department of Internal Medicine, Central Hospital of Karamay, Karamay 834000, Xinjiang Uyghur Autonomous Region, China. Electronic address: .
Hu Z; Department of Cardiovascular Diseases, Tongji Hospital of Tongji University, Shanghai 200065, China. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2021 Jan 01; Vol. 264, pp. 118721. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy*/drug effects
Foam Cells/*metabolism
Forkhead Box Protein O1/*metabolism
Lipoproteins, LDL/*metabolism
Sirtuin 1/*metabolism
Foam Cells/drug effects ; Forkhead Box Protein O1/genetics ; Gynostemma ; Humans ; Lysosomes/drug effects ; Lysosomes/metabolism ; Plant Extracts/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Sirtuin 1/genetics ; THP-1 Cells ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł:
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE mice.
Autorzy:
Wu H; Department of Endocrinology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University & The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.
Feng K; Key Laboratory of Bioactive Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, China.
Zhang C; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhang H; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhang J; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Hua Y; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Dong Z; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhu Y; Department of Endocrinology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University & The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China. Electronic address: .
Yang S; Department of Endocrinology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University & The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China. Electronic address: .
Ma C; First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jun 11; Vol. 557, pp. 334-341. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apolipoproteins E/*genetics
Atherosclerosis/*drug therapy
Autophagy/*drug effects
Foam Cells/*drug effects
Kruppel-Like Transcription Factors/*metabolism
Metformin/*pharmacology
Plaque, Atherosclerotic/*drug therapy
Animals ; Aorta/drug effects ; Aorta/metabolism ; Aorta/pathology ; Apoptosis/drug effects ; Atherosclerosis/genetics ; Atherosclerosis/metabolism ; Cholesterol/metabolism ; Diet, High-Fat ; Foam Cells/metabolism ; Kruppel-Like Transcription Factors/genetics ; Macrophages/drug effects ; Macrophages/metabolism ; Male ; Metformin/therapeutic use ; Mice ; Mice, Inbred C57BL ; Plaque, Atherosclerotic/genetics ; Plaque, Atherosclerotic/metabolism ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe

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