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Tytuł:
Baicalein inhibits macrophage lipid accumulation and inflammatory response by activating the PPARγ/LXRα pathway.
Autorzy:
Zhang ZZ; School of Medicine, Hunan Polytechnic of Environment and Biology, Hengyang Hunan, China.
Yu XH; Institute of Clinical Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Tan WH; Emergency Department, The First Affiliated Hospital of University of South China, Hengyang, Hunan, China.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2022 Sep 29; Vol. 209 (3), pp. 316-325.
Typ publikacji:
Journal Article
MeSH Terms:
Foam Cells*/metabolism
PPAR gamma*
Cholesterol/metabolism ; Flavanones ; Flavonoids/metabolism ; Flavonoids/pharmacology ; Interleukin-6/metabolism ; Liver X Receptors/genetics ; Liver X Receptors/metabolism ; Macrophages/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
A novel therapeutic strategy for atherosclerosis: autophagy-dependent cholesterol efflux.
Autorzy:
Guo H; Department of Laboratory Medicine, The First Hospital of Qiqihar, Qiqihar, 161005, China.; Department of Laboratory Medicine, Affiliated Qiqihar Hospital, Southern Medical University, Qiqihar, 161005, China.
Wei D; Department of Traditional Chinese Geriatric Medicine, The First Hospital of Qiqihar, Qiqihar, 161005, China.; Department of Traditional Chinese Geriatric Medicine, Affiliated Qiqihar Hospital, Southern Medical University, Qiqihar, 161005, China.
Liu R; Ministry of Science and Education, The First Hospital of Qiqihar, Qiqihar, 161005, China.; Ministry of Science and Education, Affiliated Qiqihar Hospital, Southern Medical University, Qiqihar, 161005, China.
Zhang C; Department of Laboratory Medicine, The First Hospital of Qiqihar, Qiqihar, 161005, China.; Department of Laboratory Medicine, Affiliated Qiqihar Hospital, Southern Medical University, Qiqihar, 161005, China.
Jiang S; Department of Laboratory Medicine, The First Hospital of Qiqihar, Qiqihar, 161005, China.; Department of Laboratory Medicine, Affiliated Qiqihar Hospital, Southern Medical University, Qiqihar, 161005, China.
Wang W; Department of Laboratory Medicine, The First Hospital of Qiqihar, Qiqihar, 161005, China.; Department of Laboratory Medicine, Affiliated Qiqihar Hospital, Southern Medical University, Qiqihar, 161005, China.
Hu H; Department of Laboratory Medicine, The First Hospital of Qiqihar, Qiqihar, 161005, China.; Department of Laboratory Medicine, Affiliated Qiqihar Hospital, Southern Medical University, Qiqihar, 161005, China.
Shen L; Qiqihar MingZhu Hospital, Qiqihar, 161000, China.
Liang X; Department of Laboratory Medicine, The First Hospital of Qiqihar, Qiqihar, 161005, China. .; Department of Laboratory Medicine, Affiliated Qiqihar Hospital, Southern Medical University, Qiqihar, 161005, China. .
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Źródło:
Journal of physiology and biochemistry [J Physiol Biochem] 2022 Aug; Vol. 78 (3), pp. 557-572. Date of Electronic Publication: 2022 Jan 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Atherosclerosis*/metabolism
Foam Cells*
ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter 1/metabolism ; Autophagy ; Cholesterol/metabolism ; Humans ; Liver X Receptors/genetics ; Liver X Receptors/metabolism
Czasopismo naukowe
Tytuł:
Blocking cholesterol efflux mechanism is a potential target for antilymphoma therapy.
Autorzy:
Yano H; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Fujiwara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Horlad H; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Pan C; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Kai K; Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Niino D; Department of Pathology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Ohsawa K; Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
Higashi M; Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
Nosaka K; Department of Hematology, Rhaumatology, and Infectious Diseases, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Okuno Y; Department of Hematology, Rhaumatology, and Infectious Diseases, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Tamaru JI; Department of Pathology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
Mukasa A; Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Matsuoka M; Department of Hematology, Rhaumatology, and Infectious Diseases, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Komohara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Kumamoto University, Kumamoto, Japan.
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Źródło:
Cancer science [Cancer Sci] 2022 Jun; Vol. 113 (6), pp. 2129-2143. Date of Electronic Publication: 2022 Apr 08.
Typ publikacji:
Journal Article
MeSH Terms:
ATP-Binding Cassette Transporters*/metabolism
Foam Cells*/metabolism
Foam Cells*/pathology
Animals ; Cholesterol/metabolism ; Cholesterol Esters/metabolism ; Humans ; Mice ; Scavenger Receptors, Class B/metabolism
Czasopismo naukowe
Tytuł:
Topical Simvastatin Improves Lesions of Diffuse Normolipemic Plane Xanthoma by Inhibiting Foam Cell Pyroptosis.
Autorzy:
Zha S; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yu X; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang X; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Gu Y; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tan Y; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lu Y; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yao Z; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 May 10; Vol. 13, pp. 865704. Date of Electronic Publication: 2022 May 10 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Foam Cells*/metabolism
Xanthomatosis*/drug therapy
Xanthomatosis*/metabolism
Child ; Humans ; Inflammation/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Ointments/metabolism ; Pyroptosis ; Simvastatin/pharmacology
Czasopismo naukowe
Tytuł:
Vascular smooth muscle cell c-Fos is critical for foam cell formation and atherosclerosis.
Autorzy:
Miao G; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China; Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University, Beijing, China.
Zhao X; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Chan SL; Vascular Biology Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Zhang L; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Li Y; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Zhang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Zhang L; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. Electronic address: .
Wang B; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. Electronic address: .
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Źródło:
Metabolism: clinical and experimental [Metabolism] 2022 Jul; Vol. 132, pp. 155213. Date of Electronic Publication: 2022 May 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis*/metabolism
Foam Cells*
Animals ; Apolipoproteins E/genetics ; Apolipoproteins E/metabolism ; Humans ; Lipoproteins, LDL/metabolism ; Lipoproteins, LDL/pharmacology ; Mice ; Muscle, Smooth, Vascular ; Myocytes, Smooth Muscle ; Rats ; Scavenger Receptors, Class E/metabolism
Czasopismo naukowe
Tytuł:
Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling.
Autorzy:
Li B; Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.; The First Clinical School of Medicine, Nanjing Medical University, Nanjing 210000, China.
Ji Y; Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.; The First Clinical School of Medicine, Nanjing Medical University, Nanjing 210000, China.
Yi C; Department of Cardiovascular Surgery, Yangzhou First People's Hospital, Yangzhou 225000, China.
Wang X; Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.; The First Clinical School of Medicine, Nanjing Medical University, Nanjing 210000, China.
Liu C; Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.; The First Clinical School of Medicine, Nanjing Medical University, Nanjing 210000, China.
Wang C; Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.; The First Clinical School of Medicine, Nanjing Medical University, Nanjing 210000, China.
Lu X; Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.
Xu X; Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.
Wang X; Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jun 29; Vol. 27 (13). Date of Electronic Publication: 2022 Jun 29.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy*
Foam Cells*/metabolism
Inflammation*/metabolism
Macrophages*/drug effects
Macrophages*/metabolism
Lipoproteins, LDL/*metabolism
Rutin/*pharmacology
Animals ; Cell Survival ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Mice ; Phosphatidylinositol 3-Kinase/metabolism ; RAW 264.7 Cells ; Signal Transduction
Czasopismo naukowe
Tytuł:
2,2',4,4'-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPARγ Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation.
Autorzy:
Ren Q; State Key Laboratory of Environmental Chemistry and Eco-Toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Xie X; State Key Laboratory of Environmental Chemistry and Eco-Toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Zhao C; State Key Laboratory of Environmental Chemistry and Eco-Toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Wen Q; State Key Laboratory of Environmental Chemistry and Eco-Toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Pan R; State Key Laboratory of Environmental Chemistry and Eco-Toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Du Y; State Key Laboratory of Environmental Chemistry and Eco-Toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2022 Jun 20; Vol. 35 (6), pp. 1023-1035. Date of Electronic Publication: 2022 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
Foam Cells*/metabolism
PPAR gamma*/metabolism
CD36 Antigens/genetics ; Cell Line ; Cholesterol/metabolism ; Ether/metabolism ; Halogenated Diphenyl Ethers ; Humans ; Liver X Receptors ; Macrophages/metabolism ; Molecular Docking Simulation ; Rosiglitazone
Czasopismo naukowe
Tytuł:
Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis.
Autorzy:
Wang B; The State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University and.; Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China.
Tang X; Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China.
Yao L; Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China.
Wang Y; Key Laboratory of Remodeling-Related Cardiovascular Diseases (Ministry of Education), Beijing Collaborative Innovation Center for Cardiovascular Disorders, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Chen Z; Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China.
Li M; Department of Cardiovascular Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Wu N; Department of Cardiovascular Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Wu D; Department of Cardiovascular Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Dai X; Department of Cardiovascular Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Jiang H; Key Laboratory of Remodeling-Related Cardiovascular Diseases (Ministry of Education), Beijing Collaborative Innovation Center for Cardiovascular Disorders, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Ai D; The State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University and.; Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China.
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Źródło:
The Journal of clinical investigation [J Clin Invest] 2022 May 16; Vol. 132 (10).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis*/metabolism
Foam Cells*/metabolism
Macrophages*/metabolism
Ubiquitin Thiolesterase*/genetics
Animals ; Lipoproteins, LDL/metabolism ; Mice ; Mice, Knockout, ApoE
Czasopismo naukowe
Tytuł:
Lipidomics reveals the dysregulated ceramide metabolism in oxidized low-density lipoprotein-induced macrophage-derived foam cell.
Autorzy:
Liu J; Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Li T; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Pei W; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Zhao Y; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Zhang X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Shi X; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Li Y; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Xu W; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
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Źródło:
Biomedical chromatography : BMC [Biomed Chromatogr] 2022 Mar; Vol. 36 (3), pp. e5297. Date of Electronic Publication: 2021 Dec 19.
Typ publikacji:
Journal Article
MeSH Terms:
Foam Cells*/metabolism
Lipidomics*
Ceramides ; Lipoproteins, LDL/metabolism ; Lipoproteins, LDL/pharmacology ; Macrophages/metabolism
Czasopismo naukowe
Tytuł:
Bioactive components to inhibit foam cell formation in atherosclerosis.
Autorzy:
Singh S; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Export Promotions Industrial Park (EPIP), Industrial Area, Vaishali District, Hajipur, Bihar, 844102, India. .
Changkija S; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Export Promotions Industrial Park (EPIP), Industrial Area, Vaishali District, Hajipur, Bihar, 844102, India.
Mudgal R; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Export Promotions Industrial Park (EPIP), Industrial Area, Vaishali District, Hajipur, Bihar, 844102, India.
Ravichandiran V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Export Promotions Industrial Park (EPIP), Industrial Area, Vaishali District, Hajipur, Bihar, 844102, India.
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Źródło:
Molecular biology reports [Mol Biol Rep] 2022 Mar; Vol. 49 (3), pp. 2487-2501. Date of Electronic Publication: 2022 Jan 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Atherosclerosis*/metabolism
Foam Cells*
Cholesterol/metabolism ; Gene Expression ; Humans ; Lipoproteins, LDL/metabolism ; Macrophages/metabolism
Czasopismo naukowe
Tytuł:
Terpene Lactucopicrin Limits Macrophage Foam Cell Formation by a Reduction of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Lipid Rafts.
Autorzy:
Li Q; Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, P. R. China.
Liu X; Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, P. R. China.
Zhang X; Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, P. R. China.
Du Y; Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, P. R. China.
Chen G; Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, P. R. China.
Xiang P; Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, P. R. China.
Ling W; Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, P. R. China.; Guangdong Provincial Key Laboratory for Food, Nutrition and Health, Guangzhou, P. R. China.; Guangdong Engineering Technology Research Center for Nutrition Translation, Guangzhou, P. R. China.
Wang D; Department of Nutrition, School of Public Health, Sun Yat-sen University (Northern Campus), Guangzhou, P. R. China.; Guangdong Provincial Key Laboratory for Food, Nutrition and Health, Guangzhou, P. R. China.; Guangdong Engineering Technology Research Center for Nutrition Translation, Guangzhou, P. R. China.
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Źródło:
Molecular nutrition & food research [Mol Nutr Food Res] 2022 Feb; Vol. 66 (4), pp. e2100905. Date of Electronic Publication: 2021 Dec 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Foam Cells*
Scavenger Receptors, Class E*
Animals ; Humans ; Lactones ; Lipoproteins, LDL/metabolism ; Macrophages ; Membrane Microdomains ; Mice ; Sesquiterpenes ; Terpenes/pharmacology
Czasopismo naukowe
Tytuł:
PPARα/γ signaling pathways are involved in Chlamydia pneumoniae-induced foam cell formation via upregulation of SR-A1 and ACAT1 and downregulation of ABCA1/G1.
Autorzy:
Wu X; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China; Department of Geriatrics, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, 316021, China.
Cheng B; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Guo X; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Wu Q; Department of Geriatrics, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Sun S; Department of Geriatrics, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
He P; Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. Electronic address: .
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Źródło:
Microbial pathogenesis [Microb Pathog] 2021 Dec; Vol. 161 (Pt B), pp. 105284. Date of Electronic Publication: 2021 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Chlamydophila pneumoniae*/metabolism
Foam Cells*/metabolism
Foam Cells*/microbiology
Signal Transduction*
ATP Binding Cassette Transporter 1/genetics ; ATP Binding Cassette Transporter 1/metabolism ; Acyltransferases ; CD36 Antigens/genetics ; CD36 Antigens/metabolism ; Down-Regulation ; Humans ; PPAR alpha/genetics ; PPAR gamma ; THP-1 Cells ; Up-Regulation
Czasopismo naukowe
Tytuł:
Angiotensin II induces the expression of periostin to promote foam cell formation in oxLDL-treated macrophages.
Autorzy:
Gao F; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Bai R; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Qin W; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Liang B; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Yang Z; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.
Yang H; Departments of Cardiology, The Second Hospital of Shanxi Medical University, Taiyuan, China. Electronic address: .
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Źródło:
International journal of cardiology [Int J Cardiol] 2022 Jan 15; Vol. 347, pp. 46-53. Date of Electronic Publication: 2021 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin II*
Foam Cells*
Cell Adhesion Molecules ; Cholesterol ; Humans ; Lipoproteins, LDL ; Macrophages
Czasopismo naukowe
Tytuł:
Foam Cell Macrophages in Tuberculosis.
Autorzy:
Agarwal P; Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom.
Gordon S; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Martinez FO; Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom.
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Źródło:
Frontiers in immunology [Front Immunol] 2021 Dec 15; Vol. 12, pp. 775326. Date of Electronic Publication: 2021 Dec 15 (Print Publication: 2021).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Foam Cells/*physiology
Lipid Droplets/*physiology
Tuberculosis/*immunology
Foam Cells/immunology ; Humans ; Triglycerides/biosynthesis
Czasopismo naukowe
Tytuł:
Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics.
Autorzy:
Duan Y; Department of Cardiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, College of Food and Biological Engineering, Hefei University of Technology, Hefei, China.
Gong K; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, College of Food and Biological Engineering, Hefei University of Technology, Hefei, China.
Xu S; Department of Cardiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Zhang F; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, College of Food and Biological Engineering, Hefei University of Technology, Hefei, China.
Meng X; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, College of Food and Biological Engineering, Hefei University of Technology, Hefei, China.
Han J; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, College of Food and Biological Engineering, Hefei University of Technology, Hefei, China. .; College of Life Sciences, Key Laboratory of Bioactive Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China. .
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Źródło:
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2022 Aug 02; Vol. 7 (1), pp. 265. Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis*/drug therapy
Atherosclerosis*/genetics
Atherosclerosis*/metabolism
Cardiovascular Diseases*/drug therapy
Cardiovascular Diseases*/genetics
Cardiovascular Diseases*/metabolism
Cholesterol ; Foam Cells/metabolism ; Foam Cells/pathology ; Homeostasis ; Humans
Czasopismo naukowe
Tytuł:
High Content Image Analysis as a Tool to Morphologically Distinguish Macrophage Activation and Determine Its Importance for Foamy Alveolar Macrophage Responses.
Autorzy:
Hoffman E; Centre for Topical Drug Delivery and Toxicology School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.
Napieralska P; Department of Biochemistry and Molecular Diagnostics, Faculty of Pharmacy, Medical University of Lodz, Lodz, Poland.
Mahendran R; Centre for Topical Drug Delivery and Toxicology School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.
Murnane D; Centre for Topical Drug Delivery and Toxicology School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.
Hutter V; Centre for Topical Drug Delivery and Toxicology School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.
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Źródło:
Frontiers in immunology [Front Immunol] 2021 Sep 01; Vol. 12, pp. 611280. Date of Electronic Publication: 2021 Sep 01 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Molecular Imaging*/methods
Foam Cells/*metabolism
Foam Cells/*pathology
Macrophage Activation/*immunology
Macrophages/*cytology
Macrophages/*metabolism
Macrophages, Alveolar/*metabolism
Macrophages, Alveolar/*pathology
Biomarkers ; Cells, Cultured ; Cytokines/metabolism ; Foam Cells/immunology ; Immunophenotyping ; Lipid Metabolism ; Macrophages/immunology ; Macrophages, Alveolar/immunology ; Nitric Oxide/metabolism ; Phagocytosis/immunology
Czasopismo naukowe
Tytuł:
Loss of CD226 protects apolipoprotein E-deficient mice from diet-induced atherosclerosis.
Autorzy:
Zhang Y; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, Shaanxi 710072, China.
Xu X; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, Shaanxi 710072, China.
Ma J; Department of Immunology, Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi 710032, China.
Liu Y; Orthopedic Department of Tangdu Hospital, Fourth Military Medical University, 1 Xinsi Road, Xi'an, Shaanxi 710032, China.
Duan C; Department of Immunology, Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi 710032, China.
Liu Y; Orthopedic Department of Tangdu Hospital, Fourth Military Medical University, 1 Xinsi Road, Xi'an, Shaanxi 710032, China.
Feng C; Orthopedic Department of Tangdu Hospital, Fourth Military Medical University, 1 Xinsi Road, Xi'an, Shaanxi 710032, China.
Li W; Orthopedic Department of Tangdu Hospital, Fourth Military Medical University, 1 Xinsi Road, Xi'an, Shaanxi 710032, China.
Wang Y; Department of Immunology, Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi 710032, China.
Cheng K; Department of Immunology, Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi 710032, China.
Zhuang R; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, Shaanxi 710072, China; Department of Immunology, Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi 710032, China. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2022 Sep 01; Vol. 1868 (9), pp. 166452. Date of Electronic Publication: 2022 May 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atherosclerosis*/genetics
Atherosclerosis*/metabolism
Cholesterol*/metabolism
Antigens, Differentiation, T-Lymphocyte/*metabolism
Animals ; Apolipoproteins E/metabolism ; Diet ; Foam Cells ; Mice
Czasopismo naukowe
Tytuł:
Atypical antipsychotic drugs deregulate the cholesterol metabolism of macrophage-foam cells by activating NOX-ROS-PPARγ-CD36 signaling pathway.
Autorzy:
Chen CH; Graduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Leu SJ; Department of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan.
Hsu CP; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Division of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Pan CC; Cardiovascular Division, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Shyue SK; Cardiovascular Division, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan. Electronic address: .
Lee TS; Graduate Institute and Department of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address: .
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Źródło:
Metabolism: clinical and experimental [Metabolism] 2021 Oct; Vol. 123, pp. 154847. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antipsychotic Agents/*pharmacology
CD36 Antigens/*metabolism
Cholesterol/*metabolism
Foam Cells/*drug effects
NADPH Oxidases/*metabolism
Reactive Oxygen Species/*metabolism
Animals ; Atherosclerosis/pathology ; Foam Cells/metabolism ; Mice ; Mice, Knockout ; Olanzapine/pharmacology ; PPAR gamma/metabolism
Czasopismo naukowe

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