Kong D; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. Mourtzinos A; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. Heegsma J; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. Blokzijl H; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. de Meijer VE; Department of Surgery, Division of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. FaberKN; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. k.n.faber@umcg.nl.
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2023 Oct 05; Vol. 14 (1), pp. 288. Date of Electronic Publication: 2023 Oct 05.
Proteomic analyses do not reveal subclinical inflammation in fatigued patients with clinically quiescent inflammatory bowel disease.
Autorzy:
Bourgonje AR; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Wichers SJ; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Hu S; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. van Dullemen HM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Visschedijk MC; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. FaberKN; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Festen EAM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Samsom JN; Division of Gastroenterology, Department of Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands. Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Spekhorst LM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. .; Department of Gastroenterology and Hepatology, Medisch Spectrum Twente, Enschede, The Netherlands. .
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Źródło:
Scientific reports [Sci Rep] 2022 Aug 26; Vol. 12 (1), pp. 14581. Date of Electronic Publication: 2022 Aug 26.
Serological biomarkers of type I, III and IV collagen turnover are associated with the presence and future progression of stricturing and penetrating Crohn's disease.
Autorzy:
Bourgonje AR; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Alexdottir MS; Biomarkers and Research, Nordic Bioscience, Herlev, Denmark. Otten AT; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Loveikyte R; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Bay-Jensen AC; Biomarkers and Research, Nordic Bioscience, Herlev, Denmark. Pehrsson M; Biomarkers and Research, Nordic Bioscience, Herlev, Denmark. van Dullemen HM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Visschedijk MC; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Festen EAM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Karsdal MA; Biomarkers and Research, Nordic Bioscience, Herlev, Denmark. FaberKN; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Mortensen JH; Biomarkers and Research, Nordic Bioscience, Herlev, Denmark. Dijkstra G; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Serological Biomarkers of Extracellular Matrix Turnover and Neutrophil Activity Are Associated with Long-Term Use of Vedolizumab in Patients with Crohn's Disease.
Autorzy:
Alexdottir MS; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark. Bourgonje AR; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. Karsdal MA; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark. Pehrsson M; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark. Loveikyte R; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. van Dullemen HM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. Visschedijk MC; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. Festen EAM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. Weersma RK; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. FaberKN; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. Dijkstra G; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. Mortensen JH; Biomarkers and Research, Nordic Bioscience, 2730 Herlev, Denmark.
Mucosal Eosinophil Abundance in Non-Inflamed Colonic Tissue Is Associated with Response to Vedolizumab Induction Therapy in Inflammatory Bowel Disease.
Autorzy:
Gabriëls RY; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Bourgonje AR; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. von Martels JZH; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Blokzijl T; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Weersma RK; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Galinsky K; Gastroenterology Drug Discovery Unit, Takeda Pharmaceuticals, Cambridge, MA 02139, USA. Juarez J; Gastroenterology Drug Discovery Unit, Takeda Pharmaceuticals, Cambridge, MA 02139, USA. FaberKN; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Kats-Ugurlu G; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Dijkstra G; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
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Źródło:
Journal of clinical medicine [J Clin Med] 2022 Jul 16; Vol. 11 (14). Date of Electronic Publication: 2022 Jul 16.
Regulation of the Intestinal Extra-Adrenal Steroidogenic Pathway Component LRH-1 by Glucocorticoids in Ulcerative Colitis.
Autorzy:
Landskron G; Innate Immunity Laboratory, Immunology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile.; Biomedicine Research Laboratory, Medical School, Universidad Finis Terrae, Santiago 7501015, Chile. Dubois-Camacho K; Innate Immunity Laboratory, Immunology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile. Orellana-Serradell O; Innate Immunity Laboratory, Immunology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile. De la Fuente M; Innate Immunity Laboratory, Immunology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile.; Biomedicine Research Laboratory, Medical School, Universidad Finis Terrae, Santiago 7501015, Chile. Parada-Venegas D; Innate Immunity Laboratory, Immunology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile.; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. Bitrán M; Innate Immunity Laboratory, Immunology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile. Diaz-Jimenez D; Molecular Endocrinology Group, Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, Durham, NC 27709, USA. Tang S; Metabolism and Nuclear Medicine Group, Fudan University Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200433, China. Cidlowski JA; Molecular Endocrinology Group, Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, Durham, NC 27709, USA. Li X; Metabolism, Genes, and Environment Group, Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, Durham, NC 27709, USA. Molina H; Innate Immunity Laboratory, Immunology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile. Gonzalez CM; School of Veterinary Medicine, Faculty of Life Sciences, Universidad Andrés Bello, Santiago 8370251, Chile. Simian D; Academic Research Unit, Clínica Las Condes, Santiago 7591018, Chile. Lubascher J; Inflammatory Bowel Disease Program, Gastroenterology Department, Clínica Las Condes, Santiago 7591018, Chile. Pola V; Institute of Biomedical Sciences, Faculty of Medicine and Faculty of Life Sciences, Universidad Andrés Bello, Santiago 8370186, Chile.; FONDAP Center for Genome Regulation, Santiago 8370146, Chile. Montecino M; Institute of Biomedical Sciences, Faculty of Medicine and Faculty of Life Sciences, Universidad Andrés Bello, Santiago 8370186, Chile.; FONDAP Center for Genome Regulation, Santiago 8370146, Chile. Blokzijl T; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. FaberKN; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. González MJ; Cell and Molecular Biology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile. Quera R; Centro de Enfermedades Digestivas, Programa Enfermedad Inflamatoria Intestinal, Clínica Universidad de Los Andes, Universidad de los Andes, Santiago 7620157, Chile. Hermoso MA; Innate Immunity Laboratory, Immunology Program, Biomedical Sciences Institute, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile.
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Źródło:
Cells [Cells] 2022 Jun 12; Vol. 11 (12). Date of Electronic Publication: 2022 Jun 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
The Effect of Phenotype and Genotype on the Plasma Proteome in Patients with Inflammatory Bowel Disease.
Autorzy:
Bourgonje AR; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands. Hu S; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands. Spekhorst LM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands. Zhernakova DV; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.; Laboratory of Genomic Diversity, Center for Computer Technologies, ITMO University, St Petersburg, Russia. Vich Vila A; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands. Li Y; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands. Voskuil MD; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands. van Berkel LA; Department of Pediatrics, Division of Gastroenterology, Erasmus University Medical Center, Rotterdam, The Netherlands. Bley Folly B; Department of Pediatrics, Division of Gastroenterology, Erasmus University Medical Center, Rotterdam, The Netherlands. Charrout M; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands.; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, The Netherlands. Mahfouz A; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands.; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. Reinders MJT; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands.; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, The Netherlands. van Heck JIP; Department of Internal Medicine and Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands. Joosten LAB; Department of Internal Medicine and Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands. Visschedijk MC; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands. van Dullemen HM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands. FaberKN; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands. Samsom JN; Department of Pediatrics, Division of Gastroenterology, Erasmus University Medical Center, Rotterdam, The Netherlands. Festen EAM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands. Dijkstra G; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands. Weersma RK; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands.
The Mitochondrial Epigenome: An Unexplored Avenue to Explain Unexplained Myopathies?
Autorzy:
Mposhi A; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Liang L; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Mennega KP; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.; Department of Laboratory Medicine, Laboratory of Metabolic Diseases, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Yildiz D; Department of Laboratory Medicine, Laboratory of Metabolic Diseases, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Kampert C; Department of Laboratory Medicine, Laboratory of Metabolic Diseases, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Hof IH; Department of Laboratory Medicine, Laboratory of Metabolic Diseases, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Jellema PG; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. de Koning TJ; Department of Genetics, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.; Department of Clinical Sciences, Lund University, Lasarettgatan 40, 221 85 Lund, Sweden. FaberKN; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Ruiters MHJ; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Niezen-Koning KE; Department of Laboratory Medicine, Laboratory of Metabolic Diseases, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Rots MG; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
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