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Wyświetlanie 1-20 z 22209
Tytuł:
Bacterial Production of Recombinant Coagulation Factor VIII Domains.
Autorzy:
Bashar S; Industry-Academia Cooperation Foundation, Hongik University, 2639 Sejong-ro, Sejong-si 30016, Republic of Korea.
Jeong HJ; Department of Biological and Chemical Engineering, Hongik University, 2639 Sejong-ro, Sejong-si 30016, Republic of Korea.
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Źródło:
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2023 Apr 01; Vol. 59 (4). Date of Electronic Publication: 2023 Apr 01.
Typ publikacji:
Journal Article
MeSH Terms:
Factor VIII*/chemistry
Factor VIII*/metabolism
Hemophilia A*
Humans ; Escherichia coli/genetics ; Blood Coagulation ; Antibodies ; Recombinant Proteins
Czasopismo naukowe
Szczegóły
Tytuł:
Ex vivo factor VIII-modified proliferating human hepatocytes therapy for haemophilia A.
Autorzy:
Zhang K; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Wu N; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Cen J; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Li J; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Wang Z; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Xia Q; Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Hui L; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.; Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
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Źródło:
Cell proliferation [Cell Prolif] 2023 May; Vol. 56 (5), pp. e13467. Date of Electronic Publication: 2023 May 17.
Typ publikacji:
Journal Article
MeSH Terms:
Factor VIII*/genetics
Hemophilia A*/genetics
Hemophilia A*/therapy
Humans ; Mice ; Animals ; Genetic Vectors ; Hepatocytes/physiology ; Liver
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cryoprecipitate for the treatment of life-threatening hemorrhage in children.
Autorzy:
Horst JA; Department of Pediatrics, Washington University, St. Louis, Missouri, USA.
Spinella PC; Department of Surgery and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Leonard JC; Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University, Columbus, Ohio, USA.
Josephson CD; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; The Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA.
Leeper CM; Department of Surgery and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
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Źródło:
Transfusion [Transfusion] 2023 May; Vol. 63 Suppl 3, pp. S10-S17. Date of Electronic Publication: 2023 Apr 26.
Typ publikacji:
Observational Study; Multicenter Study; Journal Article
MeSH Terms:
Fibrinogen*/therapeutic use
Factor VIII*/therapeutic use
Humans ; Child ; Female ; Prospective Studies ; Retrospective Studies ; Treatment Outcome ; Hemorrhage/etiology ; Hemorrhage/therapy
Czasopismo naukowe
Szczegóły
Tytuł:
Relationship between factor VIII levels and bleeding for rFVIII-SingleChain in severe hemophilia A: A repeated time-to-event analysis.
Autorzy:
Bukkems LH; Hospital Pharmacy-Clinical Pharmacology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Jönsson S; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Cnossen MH; Department of Pediatric Hematology, Erasmus University Medical Center - Sophia Children's Hospital Rotterdam, Rotterdam, The Netherlands.
Karlsson MO; Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Mathôt RAA; Hospital Pharmacy-Clinical Pharmacology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
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Corporate Authors:
OPTI-CLOT studies and the SYMPHONY consortium
Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 May; Vol. 12 (5), pp. 706-718. Date of Electronic Publication: 2023 Mar 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Factor VIII*/pharmacokinetics
Hemophilia A*/drug therapy
Humans ; Young Adult ; Adult ; Hemorrhage ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biological activity of a new recombinant human coagulation factor VIII and its efficacy in a small animal model.
Autorzy:
Wu J; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Zhang H; Beijing Tiantan Biological Products Co. Ltd., 100024, Beijing, China.
Lian T; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Ding Y; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Song C; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Li D; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Wu L; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Lei T; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China. Electronic address: .
Liang H; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China; Beijing Tiantan Biological Products Co. Ltd., 100024, Beijing, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Jan 15; Vol. 640, pp. 80-87. Date of Electronic Publication: 2022 Dec 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Factor VIII*/pharmacology
Factor VIII*/therapeutic use
Recombinant Proteins*/pharmacology
Recombinant Proteins*/therapeutic use
Animals ; Humans ; Mice ; Hemophilia A/drug therapy ; Hemorrhage ; Models, Animal
Czasopismo naukowe
Szczegóły
Tytuł:
Increased risk of dialysis circuit clotting in hemodialysis patients with COVID-19 is associated with elevated FVIII, fibrinogen and D-dimers.
Autorzy:
Sudusinghe D; Department of Physiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Riddell A; Haemophilia and Thrombosis Laboratory (Health Services Laboratories), Royal Free Hospital, London, UK.; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free Hospital, London, UK.
Gandhi T; Haemophilia and Thrombosis Laboratory (Health Services Laboratories), Royal Free Hospital, London, UK.
Chowdary P; Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free Hospital, London, UK.; Research Department of Haematology, Cancer Institute UCL, London, UK.
Davenport A; Department of Renal Medicine, Royal Free Hospital, Faculty of Medical Sciences, University College London, London, UK.
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Źródło:
Hemodialysis international. International Symposium on Home Hemodialysis [Hemodial Int] 2023 Jan; Vol. 27 (1), pp. 38-44. Date of Electronic Publication: 2022 Sep 08.
Typ publikacji:
Review; Journal Article
MeSH Terms:
COVID-19*/blood
COVID-19*/complications
Factor VIII*/analysis
Factor VIII*/metabolism
Renal Dialysis*/adverse effects
Thrombosis*/etiology
Kidney Diseases*/complications
Kidney Diseases*/therapy
Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Fibrinogen/analysis ; Heparin ; Antithrombins/blood
Czasopismo naukowe
Szczegóły
Tytuł:
Cost-effectiveness of recombinant factor VIII Fc versus emicizumab for prophylaxis in adults and adolescents with haemophilia A without inhibitors in the UK.
Autorzy:
Kragh N; Global Health Economics and Outcomes Research, Swedish Orphan Biovitrum AB (Sobi™), Stockholm, Sweden.
Tytula A; Health Economics and Outcomes Research Department, Putnam PHMR, Krakow, Poland.
Pochopien M; Economic Modelling, Assignity, Krakow, Poland.
Aballéa S; Public Health Department, Aix-Marseille University, Marseille, France.
Toumi M; Public Health Department, Aix-Marseille University, Marseille, France.
Hakimi Z; Global Health Economics and Outcomes Research, Swedish Orphan Biovitrum AB (Sobi™), Stockholm, Sweden.
Nazir J; Patient Access and Community Engagement, Swedish Orphan Biovitrum AB (Sobi™), Stockholm, Sweden.
Bystrická L; Medical Affairs and Clinical Science Haemophilia, Swedish Orphan Biovitrum AB (Sobi™), Stockholm, Sweden.
Fatoye F; Faculty of Health and Education, Manchester Metropolitan University, Manchester, UK.
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Źródło:
European journal of haematology [Eur J Haematol] 2023 Mar; Vol. 110 (3), pp. 262-270. Date of Electronic Publication: 2022 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Factor VIII*/therapeutic use
Hemophilia A*/therapy
Humans ; Adult ; Male ; Adolescent ; Cost-Benefit Analysis ; Prostate-Specific Antigen/therapeutic use ; Recombinant Fusion Proteins/therapeutic use ; United Kingdom
Czasopismo naukowe
Szczegóły
Tytuł:
Modified expi293 cell culture system using piggyBac transposon enables efficient production of human FVIII.
Autorzy:
Yoshimura T; Department of Pediatrics, Nara Medical University, 840 Shijo-Cho, Kashihara, Nara, 634-8522, Japan. .
Horiuchi K; Department of Pediatrics, Nara Medical University, 840 Shijo-Cho, Kashihara, Nara, 634-8522, Japan.
Shimonishi N; Department of Pediatrics, Nara Medical University, 840 Shijo-Cho, Kashihara, Nara, 634-8522, Japan.
Ogiwara K; Department of Pediatrics, Nara Medical University, 840 Shijo-Cho, Kashihara, Nara, 634-8522, Japan.
Horie K; Department of Physiology II, Nara Medical University, Kashihara, Nara, Japan.
Shima M; Department of Pediatrics, Nara Medical University, 840 Shijo-Cho, Kashihara, Nara, 634-8522, Japan.; The Center of Thrombosis and Hemostasis, Nara Medical University, Kashihara, Nara, Japan.
Nogami K; Department of Pediatrics, Nara Medical University, 840 Shijo-Cho, Kashihara, Nara, 634-8522, Japan. .
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Źródło:
International journal of hematology [Int J Hematol] 2023 Jan; Vol. 117 (1), pp. 56-67. Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Culture Techniques*/instrumentation
Cell Culture Techniques*/methods
Factor VIII*/biosynthesis
Genetic Therapy*/methods
Hemophilia A*/genetics
Hemophilia A*/therapy
Animals ; Cricetinae ; Humans ; Codon ; Genetic Vectors/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Budget impact of prophylactic treatment of rVIII-SingleChain in moderate and severe hemophilia A in Italy.
Autorzy:
Di Brino E; Altems Advisory SRL, Roma, Italy.
Yan S; CSL Behring King of Prussia, King of Prussia, PA, USA.
Tomic R; CSL Behring, Milan, Italy.
Panebianco M; CSL Behring, Milan, Italy.
Dlotko E; Certara USA Inc., New York, NY, USA.
Stern L; Certara USA Inc., New York, NY, USA.
Basile M; Altems Advisory SRL, Roma, Italy.
Rumi F; Altems Advisory SRL, Roma, Italy.
Cicchetti A; Altems Advisory SRL, Roma, Italy.
Marino R; University Hospital of Bari, Bari, Italy.
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Źródło:
Journal of medical economics [J Med Econ] 2023 Jan-Dec; Vol. 26 (1), pp. 554-564.
Typ publikacji:
Journal Article
MeSH Terms:
Factor VIII*/economics
Factor VIII*/therapeutic use
Hemophilia A*/drug therapy
Adult ; Humans ; Budgets ; Germany ; Hemorrhage/chemically induced ; Italy ; Costs and Cost Analysis
Czasopismo naukowe
Szczegóły
Tytuł:
Translational readthrough at F8 nonsense variants in the factor VIII B domain contributes to residual expression and lowers inhibitor association.
Autorzy:
Testa MF; Department of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Ferrara.
Lombardi S; Department of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Ferrara.
Bernardi F; Department of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Ferrara.
Ferrarese M; Department of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Ferrara.
Belvini D; Transfusion Service, Haemophilia Centre and Haematology, Castelfranco Veneto Hospital, Castelfranco Veneto.
Radossi P; Oncohematology-Oncologic Institute of Veneto, Castelfranco Veneto Hospital, Castelfranco Veneto.
Castaman G; Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Florence.
Pinotti M; Department of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Ferrara. .
Branchini A; Department of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Ferrara. .
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Źródło:
Haematologica [Haematologica] 2023 Feb 01; Vol. 108 (2), pp. 472-482. Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Factor VIII*
Hemophilia A*
Humans ; Protein Biosynthesis ; Codon, Nonsense ; Mutation, Missense ; Factor IX/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
rFVIII-Fc in severe haemophilia A: The incentive switch in case of high risk of joint bleedings.
Autorzy:
Horvais V; CHU de Nantes, Pôle Hospitalo-Universitaire 7, Biologie: Unité d'Investigation Clinique 17, Nantes, France.
Wargny M; CHU de Nantes, INSERM CIC-1413, Pôle Hospitalo-Universitaire 11, Santé Publique: Clinique des Données, Nantes, France.
Repessé Y; Haemophilia Treatment Centre CRC-MHC, University Hospital of Caen Normandie, Caen, France.
Guillet B; Haemophilia Treatment Centre CRC-MHC, Univ Rennes, CHU Rennes, Inserm, EHESP, IRSET (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, France.
Beurrier P; Haemophilia Treatment Centre CT-MHC, University Hospital of Angers, Angers, France.
Ardillon L; Haemophilia Treatment Centre CRC-MHC, University Hospital of Tours, Tours, France.
Pan-Petesch B; Haemophilia Treatment Centre CRC-MHC, University Hospital of Brest, Brest, France.
Cussac V; Haemophilia Treatment Centre, Hospital of Le Mans, Le Mans, France.
Trossaërt M; Haemophilia Treatment Centre CRC-MHC, University Hospital of Nantes, Nantes, France.
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Źródło:
European journal of clinical investigation [Eur J Clin Invest] 2022 Oct; Vol. 52 (10), pp. e13824. Date of Electronic Publication: 2022 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
Factor VIII*/pharmacology
Factor VIII*/therapeutic use
Hemophilia A*/drug therapy
Hemarthrosis/drug therapy ; Hemorrhage ; Humans ; Motivation ; Recombinant Fusion Proteins/therapeutic use ; Recombinant Proteins/therapeutic use ; Retrospective Studies
Czasopismo naukowe
Szczegóły
Tytuł:
Recombinant factor VIII protein aggregation and adsorption at the liquid-solid interface.
Autorzy:
Chae I; Department of Bioengineering, University of California, Berkeley, CA 94720, United States; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States. Electronic address: .
Han A; Bayer Corporation, Berkeley, CA 94710, United States. Electronic address: .
Sundaram J; Bayer Corporation, Berkeley, CA 94710, United States. Electronic address: .
Lee SW; Department of Bioengineering, University of California, Berkeley, CA 94720, United States; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States. Electronic address: .
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Źródło:
Journal of colloid and interface science [J Colloid Interface Sci] 2022 Dec 15; Vol. 628 (Pt A), pp. 820-828. Date of Electronic Publication: 2022 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Factor VIII*/chemistry
Factor VIII*/metabolism
Protein Aggregates*
Adsorption ; Pharmaceutical Preparations ; Recombinant Proteins/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
IL-15 blockade and rapamycin rescue multifactorial loss of factor VIII from AAV-transduced hepatocytes in hemophilia A mice.
Autorzy:
Butterfield JSS; Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32607, USA.
Yamada K; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Bertolini TB; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Syed F; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Kumar SRP; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Li X; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Arisa S; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Piñeros AR; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Tapia A; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Rogers CA; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Li N; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Rana J; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Biswas M; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Terhorst C; Division of Immunology, Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School, Boston, MA 02215, USA.
Kaufman RJ; Center for Genetic Disorders and Aging Research, Samford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
de Jong YP; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY 10065, USA.
Herzog RW; Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA. Electronic address: .
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Źródło:
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2022 Dec 07; Vol. 30 (12), pp. 3552-3569. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Factor VIII*/genetics
Interleukin-15*/genetics
Mice ; Animals ; Sirolimus/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs.
Autorzy:
Becker-Gotot J; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.
Meissner M; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.
Kotov V; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.
Jurado-Mestre B; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.
Maione A; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.
Pannek A; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.
Albert T; Institute for Experimental Hematology and Transfusion Medicine (IHT), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.
Flores C; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.
Schildberg FA; Clinic for Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany.
Gleeson PA; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.
Reipert BM; IMC University of Applied Sciences Krems, Krems, Austria.
Oldenburg J; Institute for Experimental Hematology and Transfusion Medicine (IHT), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.
Kurts C; Institute of Molecular Medicine and Experimental Immunology (IMMEI), Rheinische Friedrich-Wilhelms-Universität, Venusberg Campus 1, Bonn, Germany.
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Źródło:
The Journal of clinical investigation [J Clin Invest] 2022 Nov 15; Vol. 132 (22). Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B7-H1 Antigen*/metabolism
Factor VIII*/administration & dosage
Factor VIII*/immunology
Hemophilia A*/drug therapy
Immune Tolerance*
T-Lymphocytes, Regulatory*/immunology
Isoantibodies*/immunology
B-Lymphocytes*
Animals ; Humans ; Mice ; Programmed Cell Death 1 Receptor/metabolism ; Disease Models, Animal
Czasopismo naukowe
Szczegóły
Tytuł:
Usefulness of anti-factor VIII IgG ELISA in acquired hemophilia A follow-up.
Autorzy:
Chansavang A; Biological Hematology Department, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Philippe A; Biological Hematology Department, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Bozinovic I; Biological Hematology Department, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Ben Hadj Ali K; Biological Hematology Department, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Smadja D; Biological Hematology Department, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou; INSERM, UMR-S1140, Innovative Therapies in Haemostasis; Université de Paris-Cité, Paris, France.
Helley D; Biological Hematology Department, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou; INSERM, UMR-S970 - Paris Cardiovacasular Research Center (PARCC); Université de Paris Cité, Paris, France.
Darnige L; Biological Hematology Department, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou; INSERM, UMR-S1140, Innovative Therapies in Haemostasis, Paris, France.
Mauge L; Biological Hematology Department, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou; INSERM, UMR-S970 - Paris Cardiovacasular Research Center (PARCC); Université de Paris Cité, Paris, France. .
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Źródło:
Annals of hematology [Ann Hematol] 2022 Nov; Vol. 101 (11), pp. 2453-2460. Date of Electronic Publication: 2022 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Factor VIII*
Hemophilia A*/diagnosis
Autoantibodies ; Enzyme-Linked Immunosorbent Assay/methods ; Follow-Up Studies ; Humans ; Immunoglobulin G
SCR Disease Name:
Factor 8 deficiency, acquired
Czasopismo naukowe
Szczegóły
Tytuł:
Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts.
Autorzy:
Chun H; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Kurasawa JH; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Olivares P; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Marakasova ES; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Shestopal SA; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Hassink GU; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Karnaukhova E; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Migliorini M; Center for Vascular and Inflammatory Diseases, Departments of Surgery and Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Obi JO; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Smith AK; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Wintrode PL; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Durai P; Natural Product Informatics Research Center, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
Park K; Natural Product Informatics Research Center, Korea Institute of Science and Technology, Gangneung, Republic of Korea.
Deredge D; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Strickland DK; Center for Vascular and Inflammatory Diseases, Departments of Surgery and Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Sarafanov AG; Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
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Źródło:
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2022 Oct; Vol. 20 (10), pp. 2255-2269. Date of Electronic Publication: 2022 Aug 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:
Factor VIII*/metabolism
Low Density Lipoprotein Receptor-Related Protein-1*/metabolism
Binding Sites ; Deuterium ; Humans ; Ligands ; Lipoproteins, LDL/metabolism ; Protein Binding ; Receptors, LDL/genetics ; Receptors, LDL/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Modified moving average methodology applied to the treadmill stress testing analysis of microvolt T-wave alternans.
Autorzy:
Pereira Filho HG; Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Unidade de Eletrocardiografia, Sao Paulo, SP, 05403-900, Brazil.
Samesima N; Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Unidade de Eletrocardiografia, Sao Paulo, SP, 05403-900, Brazil.
Madaloso BA; Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Unidade de Eletrocardiografia, Sao Paulo, SP, 05403-900, Brazil.
de Oliveira Tobias NMM; Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Unidade de Eletrocardiografia, Sao Paulo, SP, 05403-900, Brazil.
Facin M; Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Unidade de Eletrocardiografia, Sao Paulo, SP, 05403-900, Brazil.
Pastore CA; Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Unidade de Eletrocardiografia, Sao Paulo, SP, 05403-900, Brazil. ecg_.
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 27; Vol. 12 (1), pp. 22454. Date of Electronic Publication: 2022 Dec 27.
Typ publikacji:
Journal Article
MeSH Terms:
Exercise Test*
Factor VIII*
Humans ; Retrospective Studies ; Arrhythmias, Cardiac/diagnosis ; Death, Sudden, Cardiac ; Electrocardiography/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transient expression of factor VIII and a chronic high-fat diet induces ER stress and late hepatocyte oncogenesis.
Autorzy:
Pierce GF; World Federation of Hemophilia, Montreal, QC, Canada. Electronic address: .
Mattis AN; Department of Pathology and Liver Center, University of California San Francisco, San Francisco, CA, USA.
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Źródło:
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2022 Dec 07; Vol. 30 (12), pp. 3510-3512. Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Factor VIII*/genetics
Diet, High-Fat*/adverse effects
Humans ; Cell Transformation, Neoplastic/genetics ; Carcinogenesis/genetics ; Hepatocytes
Czasopismo naukowe
Szczegóły
Tytuł:
Efficacy, safety and pharmacokinetics of recombinant human coagulation factor VIII (omfiloctocog alfa) in previously treated Chinese children with severe hemophilia A.
Autorzy:
Wu R; Beijing, Children's Hospital, Capital Medical University, Beijing, People's Republic of China.
Wang X; Beijing, Children's Hospital, Capital Medical University, Beijing, People's Republic of China.
Zhao X; Xiangya Hospital Central South University, Hunan, People's Republic of China.
Cheng Y; Shanxi Provincial Children's Hospital, Shanxi, People's Republic of China.
Zhou Z; The Second Affiliated Hospital of Kunming Medical University, Yunnan, People's Republic of China.
Sun J; Nanfang Hospital Affiliated to Southern Medical University, Guangdong, People's Republic of China.
Xu M; Chengdu Women's & Children's Central Hospital, Sichuan, People's Republic of China.
Li W; Qinghai Provincial People's Hospital, Qinghai, People's Republic of China.
Xiao J; The Affiliated Children's Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Yang F; Fujian Medical University Union Hospital, Fujian, People's Republic of China.
Chen Y; Jinan Central Hospital, Shandong, People's Republic of China.
Xu W; The Affiliated Children's Hospital of Zhejiang Medical University, Zhejiang, People's Republic of China.
Huang J; The Affiliated Hospital of Guizhou Medical University, Guangdong, People's Republic of China.
Ma C; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, People's Republic of China.
Gai W; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, People's Republic of China.
Xie L; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing, People's Republic of China.
Yang R; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Hematological Disorders, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, People's Republic of China.
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Źródło:
Haemophilia : the official journal of the World Federation of Hemophilia [Haemophilia] 2022 Nov; Vol. 28 (6), pp. e199-e208. Date of Electronic Publication: 2022 Jul 08.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Factor VIII*/adverse effects
Hemophilia A*
Humans ; Child ; Hemorrhage/etiology ; Hemorrhage/prevention & control ; Recombinant Proteins/adverse effects ; China ; Treatment Outcome
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 22209

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