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    Tytuł:
    Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer's disease.
    Autorzy:
    Lynch MT; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
    Taub MA; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
    Farfel JM; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
    Yang J; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
    Abadir P; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
    De Jager PL; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
    Grodstein F; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
    Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
    Mathias RA; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. .
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    Źródło:
    Scientific reports [Sci Rep] 2023 Sep 07; Vol. 13 (1), pp. 14747. Date of Electronic Publication: 2023 Sep 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
    MeSH Terms:
    Alzheimer Disease*/genetics
    Hippocampal Sclerosis*
    Humans ; Genomics ; Brain ; DNA, Mitochondrial ; Aging/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Brain autopsies of critically ill COVID-19 patients demonstrate heterogeneous profile of acute vascular injury, inflammation and age-linked chronic brain diseases.
    Autorzy:
    Agrawal S; Rush Alzheimer's Disease Center, Rush University Medical Center, Jelke Building, 1750 W. Harrison Street, Chicago, IL, 60612, USA. sonal_.; Department of Pathology, Rush University Medical Center, Chicago, IL, USA. sonal_.
    Farfel JM; Rush Alzheimer's Disease Center, Rush University Medical Center, Jelke Building, 1750 W. Harrison Street, Chicago, IL, 60612, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
    Arfanakis K; Rush Alzheimer's Disease Center, Rush University Medical Center, Jelke Building, 1750 W. Harrison Street, Chicago, IL, 60612, USA.; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA.
    Al-Harthi L; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, USA.
    Shull T; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, USA.
    Teppen TL; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, USA.
    Evia AM; Rush Alzheimer's Disease Center, Rush University Medical Center, Jelke Building, 1750 W. Harrison Street, Chicago, IL, 60612, USA.
    Patel MB; Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; The Geriatric Research Education Clinical Center (GRECC), Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System (TVHS), Nashville, TN, USA.
    Ely EW; Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; The Geriatric Research Education Clinical Center (GRECC), Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System (TVHS), Nashville, TN, USA.
    Leurgans SE; Rush Alzheimer's Disease Center, Rush University Medical Center, Jelke Building, 1750 W. Harrison Street, Chicago, IL, 60612, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
    Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Jelke Building, 1750 W. Harrison Street, Chicago, IL, 60612, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
    Mehta R; Rush Alzheimer's Disease Center, Rush University Medical Center, Jelke Building, 1750 W. Harrison Street, Chicago, IL, 60612, USA.; Department of Pathology, Rush University Medical Center, Chicago, IL, USA.
    Schneider JA; Rush Alzheimer's Disease Center, Rush University Medical Center, Jelke Building, 1750 W. Harrison Street, Chicago, IL, 60612, USA.; Department of Pathology, Rush University Medical Center, Chicago, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
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    Źródło:
    Acta neuropathologica communications [Acta Neuropathol Commun] 2022 Dec 17; Vol. 10 (1), pp. 186. Date of Electronic Publication: 2022 Dec 17.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    COVID-19*/pathology
    Vascular System Injuries*/pathology
    Encephalitis*/pathology
    Humans ; Male ; Female ; SARS-CoV-2 ; Autopsy ; Critical Illness ; Brain/pathology ; Inflammation/pathology ; RNA, Viral
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Dementia and autopsy-verified causes of death in racially-diverse older Brazilians.
    Autorzy:
    Farfel JM; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, United States of America.; Department of Pathology, Rush University Medical Center, Chicago, IL, United States of America.; Health Sciences Program, Instituto de Assistência Medica ao Servidor Público do Estado (IAMSPE), São Paulo, Brazil.
    Leurgans SE; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, United States of America.; Department of Neurological Sciences, Rush Medical College, Chicago, IL, United States of America.
    Capuano AW; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, United States of America.; Health Sciences Program, Instituto de Assistência Medica ao Servidor Público do Estado (IAMSPE), São Paulo, Brazil.; Department of Neurological Sciences, Rush Medical College, Chicago, IL, United States of America.
    de Moraes Sampaio MC; Health Sciences Program, Instituto de Assistência Medica ao Servidor Público do Estado (IAMSPE), São Paulo, Brazil.
    Wilson RS; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, United States of America.; Department of Neurological Sciences, Rush Medical College, Chicago, IL, United States of America.; Department of Psychiatry and Behavioral Sciences, Rush Medical College, Chicago, IL, United States of America.
    Schneider JA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, United States of America.; Department of Pathology, Rush University Medical Center, Chicago, IL, United States of America.; Department of Neurological Sciences, Rush Medical College, Chicago, IL, United States of America.
    Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, United States of America.; Health Sciences Program, Instituto de Assistência Medica ao Servidor Público do Estado (IAMSPE), São Paulo, Brazil.; Department of Neurological Sciences, Rush Medical College, Chicago, IL, United States of America.
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    Źródło:
    PloS one [PLoS One] 2021 Dec 15; Vol. 16 (12), pp. e0261036. Date of Electronic Publication: 2021 Dec 15 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Cause of Death*
    Dementia/*complications
    Aged ; Aged, 80 and over ; Autopsy ; Brazil ; Dementia/ethnology ; Educational Status ; Female ; Humans ; Male
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Association between health literacy and glycemic control in elderly patients with type 2 diabetes and modifying effect of social support.
    Autorzy:
    Souza JG; Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, BA, Brazil.
    Farfel JM; Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Jaluul O; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Queiroz MS; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Nery M; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
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    Źródło:
    Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2020 Dec 07; Vol. 18, pp. eAO5572. Date of Electronic Publication: 2020 Dec 07 (Print Publication: 2020).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Diabetes Mellitus, Type 2*
    Health Literacy*
    Aged ; Blood Glucose ; Cross-Sectional Studies ; Glycated Hemoglobin/analysis ; Glycemic Control ; Humans ; Middle Aged ; Social Support
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Alzheimer's disease frequency peaks in the tenth decade and is lower afterwards.
    Autorzy:
    Farfel JM; Rush Alzheimer's Disease Center, Rush University Medical Center, 1750 W. Harrison, Suite 1000, Chicago, IL, 60612, USA. Jose_Farfel@rush.edu.; Department of Pathology, Rush University Medical Center, Chicago, IL, USA. Jose_Farfel@rush.edu.; Department of Geriatrics, University of Sao Paulo Medical School, Sao Paulo, Brazil. Jose_Farfel@rush.edu.
    Yu L; Rush Alzheimer's Disease Center, Rush University Medical Center, 1750 W. Harrison, Suite 1000, Chicago, IL, 60612, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
    Boyle PA; Rush Alzheimer's Disease Center, Rush University Medical Center, 1750 W. Harrison, Suite 1000, Chicago, IL, 60612, USA.; Department of Behavioral Sciences, Rush Medical College, Chicago, IL, USA.
    Leurgans S; Rush Alzheimer's Disease Center, Rush University Medical Center, 1750 W. Harrison, Suite 1000, Chicago, IL, 60612, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
    Shah RC; Rush Alzheimer's Disease Center, Rush University Medical Center, 1750 W. Harrison, Suite 1000, Chicago, IL, 60612, USA.; Department of Family Medicine, Rush Medical College, Chicago, IL, USA.
    Schneider JA; Rush Alzheimer's Disease Center, Rush University Medical Center, 1750 W. Harrison, Suite 1000, Chicago, IL, 60612, USA.; Department of Pathology, Rush University Medical Center, Chicago, IL, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
    Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, 1750 W. Harrison, Suite 1000, Chicago, IL, 60612, USA.; Department of Geriatrics, University of Sao Paulo Medical School, Sao Paulo, Brazil.; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
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    Źródło:
    Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Jul 03; Vol. 7 (1), pp. 104. Date of Electronic Publication: 2019 Jul 03.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Aging/*pathology
    Alzheimer Disease/*epidemiology
    Alzheimer Disease/*pathology
    Aged ; Aged, 80 and over ; Aging/psychology ; Alzheimer Disease/psychology ; Cognitive Dysfunction/epidemiology ; Cognitive Dysfunction/pathology ; Cognitive Dysfunction/psychology ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Male ; Neuropsychological Tests
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Initial findings of striatum tripartite model in OCD brain samples based on transcriptome analysis.
    Autorzy:
    Lisboa BCG; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Oliveira KC; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Tahira AC; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Barbosa AR; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.; Inter-institutional Grad Program on Bioinformatics, University of Sao Paulo, Sao Paulo, SP, Brazil.
    Feltrin AS; Center of Mathematics, Computation and Cognition, Federal University of ABC, Santo Andre, SP, Brazil.
    Gouveia G; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Lima L; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Feio Dos Santos AC; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Martins DC Jr; Center of Mathematics, Computation and Cognition, Federal University of ABC, Santo Andre, SP, Brazil.
    Puga RD; Academic Research Organization-Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil.
    Moretto AC; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    De Bragança Pereira CA; Inter-institutional Grad Program on Bioinformatics, University of Sao Paulo, Sao Paulo, SP, Brazil.
    Lafer B; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Leite REP; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Ferretti-Rebustini REL; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Farfel JM; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Grinberg LT; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.; Memory and Aging Center University of California, San Francisco, USA.
    Jacob-Filho W; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Miguel EC; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Hoexter MQ; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
    Brentani H; Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil. .; Inter-institutional Grad Program on Bioinformatics, University of Sao Paulo, Sao Paulo, SP, Brazil. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Feb 28; Vol. 9 (1), pp. 3086. Date of Electronic Publication: 2019 Feb 28.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Caudate Nucleus*/metabolism
    Caudate Nucleus*/physiopathology
    Nucleus Accumbens*/metabolism
    Nucleus Accumbens*/physiopathology
    Putamen*/metabolism
    Putamen*/physiopathology
    Transcriptome*
    Neural Pathways/*physiopathology
    Obsessive-Compulsive Disorder/*physiopathology
    Aged ; Aged, 80 and over ; Brain Mapping/methods ; Case-Control Studies ; Female ; Gene Expression Profiling/methods ; Humans ; Male
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Morphometric measurements of systemic atherosclerosis and visceral fat: Evidence from an autopsy study.
    Autorzy:
    Nishizawa A; Laboratory of Cardiovascular Pathology (LIM-22), Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil.; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Suemoto CK; Laboratory of Cardiovascular Pathology (LIM-22), Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil.; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.; Discipline of Geriatrics, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Farias-Itao DS; Laboratory of Cardiovascular Pathology (LIM-22), Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil.; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Campos FM; Laboratory of Cardiovascular Pathology (LIM-22), Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Silva KCS; Laboratory of Cardiovascular Pathology (LIM-22), Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil.; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Bittencourt MS; Division of Internal Medicine, University Hospital and State of São Paulo Cancer Institute (ICESP), University of São Paulo, Sao Paulo, Brazil.; Preventive Medicine Center, Hospital Israelita Albert Einstein and School of Medicine, Faculdade Israelita de Ciência da Saúde Albert Einstein, São Paulo, Brazil.
    Grinberg LT; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.; Department of Neurology, Memory and Aging Center, University of California, San Francisco, United States of America.; Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Leite REP; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.; Discipline of Geriatrics, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Ferretti-Rebustini REL; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.; Department of Medical Surgical Nursing, University of São Paulo Nursing School, Sao Paulo, Brazil.
    Farfel JM; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.; Discipline of Geriatrics, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Jacob-Filho W; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.; Discipline of Geriatrics, University of Sao Paulo Medical School, Sao Paulo, Brazil.
    Pasqualucci CA; Laboratory of Cardiovascular Pathology (LIM-22), Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil.; Pathophysiology in Aging Lab/Brazilian Aging Brain Study Group (LIM-22), University of Sao Paulo Medical School, Sao Paulo, Brazil.; Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil.
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    Źródło:
    PloS one [PLoS One] 2017 Oct 16; Vol. 12 (10), pp. e0186630. Date of Electronic Publication: 2017 Oct 16 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Atherosclerosis/*pathology
    Intra-Abdominal Fat/*pathology
    Adult ; Aged ; Aged, 80 and over ; Arteries/pathology ; Autopsy ; Female ; Humans ; Male ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease.
    Autorzy:
    Ehrenberg AJ; University of California, San Francisco, California, USA.; University of California, Berkeley, California, USA.
    Nguy AK; University of California, San Francisco, California, USA.; University of California, Berkeley, California, USA.
    Theofilas P; University of California, San Francisco, California, USA.
    Dunlop S; University of California, San Francisco, California, USA.
    Suemoto CK; University of São Paulo Medical School, São Paulo, Brazil.
    Di Lorenzo Alho AT; University of São Paulo Medical School, São Paulo, Brazil.; Hospital Israelita Albert Einstein, São Paulo, Brazil.
    Leite RP; University of São Paulo Medical School, São Paulo, Brazil.
    Diehl Rodriguez R; University of São Paulo Medical School, São Paulo, Brazil.
    Mejia MB; University of California, San Francisco, California, USA.
    Rüb U; University of Frankfurt, Frankfurt, Germany.
    Farfel JM; University of São Paulo Medical School, São Paulo, Brazil.
    de Lucena Ferretti-Rebustini RE; University of São Paulo, School of Nursing, São Paulo, Brazil.
    Nascimento CF; University of São Paulo Medical School, São Paulo, Brazil.
    Nitrini R; University of São Paulo Medical School, São Paulo, Brazil.
    Pasquallucci CA; University of São Paulo Medical School, São Paulo, Brazil.
    Jacob-Filho W; University of São Paulo Medical School, São Paulo, Brazil.
    Miller B; University of California, San Francisco, California, USA.
    Seeley WW; University of California, San Francisco, California, USA.
    Heinsen H; University of São Paulo Medical School, São Paulo, Brazil.; University of Wüerzburg, Wüerzburg, Germany.
    Grinberg LT; University of California, San Francisco, California, USA.; University of São Paulo Medical School, São Paulo, Brazil.
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    Źródło:
    Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2017 Aug; Vol. 43 (5), pp. 393-408. Date of Electronic Publication: 2017 Mar 31.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Alzheimer Disease/*pathology
    Dorsal Raphe Nucleus/*pathology
    Locus Coeruleus/*pathology
    tau Proteins/*metabolism
    Adult ; Aged ; Aged, 80 and over ; Alzheimer Disease/metabolism ; Disease Progression ; Dorsal Raphe Nucleus/metabolism ; Female ; Humans ; Inclusion Bodies/pathology ; Locus Coeruleus/metabolism ; Male ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Neuropathological diagnoses and clinical correlates in older adults in Brazil: A cross-sectional study.
    Autorzy:
    Suemoto CK; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.; Division of Geriatrics, University of São Paulo Medical School, São Paulo, Brazil.
    Ferretti-Rebustini RE; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.; Department of Medical Surgical Nursing, University of São Paulo Nursing School, São Paulo, Brazil.
    Rodriguez RD; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.; Department of Pathology, University of São Paulo Medical School, São Paulo, Brazil.
    Leite RE; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.; Division of Geriatrics, University of São Paulo Medical School, São Paulo, Brazil.
    Soterio L; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.
    Brucki SM; Department of Neurology, University of São Paulo Medical School, São Paulo, Brazil.
    Spera RR; Department of Neurology, University of São Paulo Medical School, São Paulo, Brazil.
    Cippiciani TM; Department of Neurology, University of São Paulo Medical School, São Paulo, Brazil.
    Farfel JM; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.; Division of Geriatrics, University of São Paulo Medical School, São Paulo, Brazil.
    Chiavegatto Filho A; Department of Epidemiology, School of Public Health, University of São Paulo, São Paulo, Brazil.
    Naslavsky MS; Human Genome and Stem Cell Center, Biosciences Institute, University of São Paulo, São Paulo, Brazil.
    Zatz M; Human Genome and Stem Cell Center, Biosciences Institute, University of São Paulo, São Paulo, Brazil.
    Pasqualucci CA; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.; Department of Pathology, University of São Paulo Medical School, São Paulo, Brazil.
    Jacob-Filho W; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.; Division of Geriatrics, University of São Paulo Medical School, São Paulo, Brazil.
    Nitrini R; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.; Department of Neurology, University of São Paulo Medical School, São Paulo, Brazil.
    Grinberg LT; Brazilian Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.; Department of Pathology, University of São Paulo Medical School, São Paulo, Brazil.; Memory and Aging Center, University of California San Francisco, San Francisco, California, United States of America.
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    Źródło:
    PLoS medicine [PLoS Med] 2017 Mar 28; Vol. 14 (3), pp. e1002267. Date of Electronic Publication: 2017 Mar 28 (Print Publication: 2017).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Dementia/*epidemiology
    Aged ; Aged, 80 and over ; Alzheimer Disease/epidemiology ; Alzheimer Disease/pathology ; Brazil/epidemiology ; Cognition ; Cross-Sectional Studies ; Dementia/pathology ; Dementia, Vascular/epidemiology ; Dementia, Vascular/pathology ; Female ; Humans ; Male ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Applicability of the Spoken Knowledge in Low Literacy Patients with Diabetes in Brazilian elderly.
    Autorzy:
    Souza JG; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Apolinario D; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Farfel JM; Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Jaluul O; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Magaldi RM; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Busse AL; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Campora F; Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
    Jacob-Filho W; Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
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    Źródło:
    Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2016 Oct-Dec; Vol. 14 (4), pp. 513-519.
    Typ publikacji:
    Evaluation Study; Journal Article
    MeSH Terms:
    Diabetes Mellitus, Type 2*
    Health Literacy*
    Surveys and Questionnaires*
    Aged ; Aged, 80 and over ; Brazil ; Cross-Sectional Studies ; Female ; Geriatric Assessment ; Humans ; Male ; Psychometrics ; Socioeconomic Factors ; Translations
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Olfaction in neurologic and neurodegenerative diseases: a literature review.
    Autorzy:
    Godoy MD; Department of Otorhinolaryngology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.
    Voegels RL; Department of Otorhinolaryngology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.
    Pinna Fde R; Department of Otorhinolaryngology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.
    Imamura R; Department of Otorhinolaryngology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.
    Farfel JM; Department of Geriatrics, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
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    Źródło:
    International archives of otorhinolaryngology [Int Arch Otorhinolaryngol] 2015 Apr; Vol. 19 (2), pp. 176-9. Date of Electronic Publication: 2014 Nov 14.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Sexual dimorphism in the human olfactory bulb: females have more neurons and glial cells than males.
    Autorzy:
    Oliveira-Pinto AV; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
    Santos RM; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
    Coutinho RA; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
    Oliveira LM; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
    Santos GB; Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil; Brain Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
    Alho AT; Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil; Brain Institute, Hospital Israelita Albert Einstein, São Paulo, Brazil.
    Leite RE; Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.
    Farfel JM; Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil; Discipline of Geriatrics, University of São Paulo Medical School, São Paulo, Brazil.
    Suemoto CK; Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil; Discipline of Geriatrics, University of São Paulo Medical School, São Paulo, Brazil.
    Grinberg LT; Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil; Department of Neurology and Pathology, University of California San Francisco, San Francisco, United States of America.
    Pasqualucci CA; Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil.
    Jacob-Filho W; Aging Brain Study Group, University of São Paulo Medical School, São Paulo, Brazil; Discipline of Geriatrics, University of São Paulo Medical School, São Paulo, Brazil.
    Lent R; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; National Institute of Translational Neuroscience, Ministry of Science and Technology, São Paulo, Brazil.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2014 Nov 05; Vol. 9 (11), pp. e111733. Date of Electronic Publication: 2014 Nov 05 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Sex Characteristics*
    Olfactory Bulb/*cytology
    Aged ; Aged, 80 and over ; Cell Count ; Female ; Humans ; Male ; Middle Aged ; Neuroglia/cytology ; Neurons/cytology ; Olfactory Bulb/anatomy & histology ; Organ Size ; Sex Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease.
    Autorzy:
    Silva AR; Laboratory of Clinical Pathology - Laboratory of Medical Investigations 23 (LIM 23), Department and Institute of Psychiatry, University of São Paulo, Medical School, São Paulo, Brazil.
    Santos AC; Laboratory of Clinical Pathology - Laboratory of Medical Investigations 23 (LIM 23), Department and Institute of Psychiatry, University of São Paulo, Medical School, São Paulo, Brazil.
    Farfel JM; Brazilian Brain Bank of the Aging Brain Study Group - Laboratory of Medical Investigations 22 (LIM 22), University of São Paulo, Medical School, São Paulo, Brazil; Division of Geriatrics, University of São Paulo, Medical School, São Paulo, Brazil.
    Grinberg LT; Brazilian Brain Bank of the Aging Brain Study Group - Laboratory of Medical Investigations 22 (LIM 22), University of São Paulo, Medical School, São Paulo, Brazil; Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America.
    Ferretti RE; Brazilian Brain Bank of the Aging Brain Study Group - Laboratory of Medical Investigations 22 (LIM 22), University of São Paulo, Medical School, São Paulo, Brazil; Division of Geriatrics, University of São Paulo, Medical School, São Paulo, Brazil.
    Campos AH; Department of Pathology, A. C. Camargo Cancer Center, São Paulo, Brazil.
    Cunha IW; Department of Pathology, A. C. Camargo Cancer Center, São Paulo, Brazil.
    Begnami MD; Department of Pathology, A. C. Camargo Cancer Center, São Paulo, Brazil.
    Rocha RM; Research Center (CIPE), A. C. Camargo Cancer Center, São Paulo, Brazil.
    Carraro DM; Research Center (CIPE), A. C. Camargo Cancer Center, São Paulo, Brazil.
    de Bragança Pereira CA; Mathematics and Statistics Institute, University of São Paulo, São Paulo, Brazil.
    Jacob-Filho W; Brazilian Brain Bank of the Aging Brain Study Group - Laboratory of Medical Investigations 22 (LIM 22), University of São Paulo, Medical School, São Paulo, Brazil; Division of Geriatrics, University of São Paulo, Medical School, São Paulo, Brazil.
    Brentani H; Laboratory of Clinical Pathology - Laboratory of Medical Investigations 23 (LIM 23), Department and Institute of Psychiatry, University of São Paulo, Medical School, São Paulo, Brazil.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2014 Jun 17; Vol. 9 (6), pp. e99897. Date of Electronic Publication: 2014 Jun 17 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Apoptosis*
    DNA Damage*
    DNA Repair*
    Alzheimer Disease/*pathology
    Neurons/*physiology
    Aged, 80 and over ; Alzheimer Disease/metabolism ; Cell Cycle ; Female ; Hippocampus/metabolism ; Hippocampus/pathology ; Humans ; Male ; Oxidative Stress ; Tissue Array Analysis ; Transcriptome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Estimating premorbid cognitive abilities in low-educated populations.
    Autorzy:
    Apolinario D; Geriatrics Division, Department of Internal Medicine, University of São Paulo Medical School, São Paulo, São Paulo, Brazil. />Brucki SM
    Ferretti RE
    Farfel JM
    Magaldi RM
    Busse AL
    Jacob-Filho W
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2013; Vol. 8 (3), pp. e60084. Date of Electronic Publication: 2013 Mar 21.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cognition Disorders/*physiopathology
    Educational Status ; Female ; Humans ; Intelligence/physiology ; Male ; Middle Aged ; Neuropsychological Tests ; Principal Component Analysis ; Surveys and Questionnaires
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease.
    Autorzy:
    Silva AR; Research Center-CIPE, A. C. Camargo Hospital, Sao Paulo, Brazil.
    Grinberg LT
    Farfel JM
    Diniz BS
    Lima LA
    Silva PJ
    Ferretti RE
    Rocha RM
    Filho WJ
    Carraro DM
    Brentani H
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2012; Vol. 7 (11), pp. e48751. Date of Electronic Publication: 2012 Nov 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease/*genetics
    Alzheimer Disease/complications ; Alzheimer Disease/pathology ; Brain/metabolism ; Brain/pathology ; Cellular Senescence/genetics ; Cluster Analysis ; DNA Damage ; DNA Repair/genetics ; Dementia/etiology ; Dementia/genetics ; Dementia/pathology ; Energy Metabolism/genetics ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Regulatory Networks ; Oligonucleotide Array Sequence Analysis ; Oxidative Stress/genetics ; Transcriptome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Adverse drug events leading to emergency department visits in elderly: the role of inappropriate prescription.
    Autorzy:
    Farfel JM; Advanced Unit Ibirapuera, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
    Accorsi TA; Advanced Unit Ibirapuera, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
    Franken M; Advanced Unit Ibirapuera, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
    Doudement SP; Advanced Unit Ibirapuera, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
    Moran M; Advanced Unit Ibirapuera, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
    Iervolino M; Advanced Unit Ibirapuera, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
    Bastos Neto AS; Advanced Unit Ibirapuera, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
    Pokaż więcej
    Źródło:
    Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2010 Jun; Vol. 8 (2), pp. 175-9.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?
    Autorzy:
    Grinberg LT; Department of Pathology, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil.
    Rüb U
    Ferretti RE
    Nitrini R
    Farfel JM
    Polichiso L
    Gierga K
    Jacob-Filho W
    Heinsen H
    Pokaż więcej
    Corporate Authors:
    Brazilian Brain Bank Study Group
    Źródło:
    Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2009 Aug; Vol. 35 (4), pp. 406-16.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease/*pathology
    Entorhinal Cortex/*pathology
    Neurofibrillary Tangles/*pathology
    Raphe Nuclei/*pathology
    tau Proteins/*metabolism
    Aged ; Aged, 80 and over ; Alzheimer Disease/epidemiology ; Alzheimer Disease/metabolism ; Depressive Disorder, Major/epidemiology ; Disease Progression ; Education ; Entorhinal Cortex/cytology ; Entorhinal Cortex/metabolism ; Female ; Humans ; Male ; Middle Aged ; Neurofibrillary Tangles/metabolism ; Phosphorylation ; Raphe Nuclei/cytology ; Raphe Nuclei/metabolism ; Severity of Illness Index
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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