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Wyświetlanie 1-5 z 5
Tytuł :
Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.
Autorzy :
Okoye AA; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Hansen SG; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Vaidya M; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Fukazawa Y; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Park H; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Duell DM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Lum R; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Hughes CM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Ventura AB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Ainslie E; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Ford JC; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Morrow D; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Gilbride RM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Legasse AW; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Hesselgesser J; Gilead Sciences, Inc., Foster City, CA, USA.
Geleziunas R; Gilead Sciences, Inc., Foster City, CA, USA.
Li Y; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Oswald K; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Shoemaker R; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Fast R; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Bosche WJ; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Borate BR; Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Edlefsen PT; Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Axthelm MK; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Picker LJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA. .
Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA. .
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Źródło :
Nature medicine [Nat Med] 2018 Sep; Vol. 24 (9), pp. 1430-1440. Date of Electronic Publication: 2018 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Retroviral Agents/*therapeutic use
Simian Acquired Immunodeficiency Syndrome/*drug therapy
Simian Acquired Immunodeficiency Syndrome/*virology
Simian Immunodeficiency Virus/*physiology
Adoptive Transfer ; Animals ; Anti-Retroviral Agents/pharmacology ; Drug Therapy, Combination ; Kinetics ; Macaca mulatta ; Necrosis ; Simian Immunodeficiency Virus/drug effects ; Vaccination ; Viral Vaccines/immunology ; Viremia/drug therapy ; Virus Replication
Czasopismo naukowe
Tytuł :
CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.
Autorzy :
Cartwright EK; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Spicer L; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Smith SA; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Lee D; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Fast R; AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Paganini S; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Lawson BO; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Nega M; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Easley K; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Atlanta, GA 30329, USA.
Schmitz JE; Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Bosinger SE; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Paiardini M; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Chahroudi A; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Vanderford TH; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Estes JD; AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Lifson JD; AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Derdeyn CA; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Silvestri G; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA. Electronic address: .
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Źródło :
Immunity [Immunity] 2016 Sep 20; Vol. 45 (3), pp. 656-668.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Retroviral Agents/*pharmacology
CD8-Positive T-Lymphocytes/*immunology
Simian Acquired Immunodeficiency Syndrome/*drug therapy
Simian Acquired Immunodeficiency Syndrome/*immunology
Simian Immunodeficiency Virus/*immunology
Animals ; Antibodies, Viral/immunology ; Antiretroviral Therapy, Highly Active/methods ; CD4-Positive T-Lymphocytes/drug effects ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/drug effects ; Female ; Lymphocyte Depletion/methods ; Macaca mulatta ; Male ; Simian Acquired Immunodeficiency Syndrome/virology ; Simian Immunodeficiency Virus/drug effects ; Viral Load/drug effects ; Viral Load/immunology ; Viremia/drug therapy ; Viremia/immunology ; Viremia/virology ; Virus Replication/drug effects ; Virus Replication/immunology
Czasopismo naukowe
Tytuł :
Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy.
Autorzy :
Del Prete GQ; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Oswald K; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Lara A; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Shoemaker R; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Smedley J; Laboratory Animal Sciences Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Macallister R; Laboratory Animal Sciences Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Coalter V; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Wiles A; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Wiles R; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Li Y; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Fast R; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Kiser R; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Lu B; Gilead Sciences, Foster City, California, USA.
Zheng J; Gilead Sciences, Foster City, California, USA.
Alvord WG; Statistical Consulting, Data Management Services, Inc., Frederick, Maryland, USA.
Trubey CM; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Piatak M Jr; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Deleage C; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Keele BF; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Estes JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Hesselgesser J; Gilead Sciences, Foster City, California, USA.
Geleziunas R; Gilead Sciences, Foster City, California, USA.
Lifson JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA .
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2015 Dec 28; Vol. 60 (3), pp. 1560-72. Date of Electronic Publication: 2015 Dec 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Depsipeptides/*therapeutic use
Histone Deacetylase Inhibitors/*therapeutic use
Macaca mulatta/*virology
RNA, Viral/*blood
Simian Acquired Immunodeficiency Syndrome/*drug therapy
Simian Immunodeficiency Virus/*drug effects
Viral Load/*drug effects
Acetylation ; Animals ; Antiretroviral Therapy, Highly Active ; CD4-Positive T-Lymphocytes/metabolism ; Depsipeptides/pharmacokinetics ; Histone Deacetylase Inhibitors/pharmacokinetics ; Histones/metabolism ; Viremia/drug therapy ; Virus Activation/drug effects
Czasopismo naukowe
Tytuł :
Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques.
Autorzy :
Del Prete GQ; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Shoemaker R; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Oswald K; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Lara A; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Trubey CM; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Fast R; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Schneider DK; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Kiser R; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Coalter V; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Wiles A; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Wiles R; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Freemire B; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Keele BF; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Estes JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Quiñones OA; Statistical Consulting, Data Management Services, Inc., Frederick, Maryland, USA.
Smedley J; Laboratory Animal Sciences Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Macallister R; Laboratory Animal Sciences Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Sanchez RI; Merck Research Labs, West Point, Pennsylvania, USA.
Wai JS; Merck Research Labs, West Point, Pennsylvania, USA.
Tan CM; Merck Research Labs, Kenilworth, New Jersey, USA.
Alvord WG; Statistical Consulting, Data Management Services, Inc., Frederick, Maryland, USA.
Hazuda DJ; Merck Research Labs, West Point, Pennsylvania, USA.
Piatak M Jr; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Lifson JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA .
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2014 Nov; Vol. 58 (11), pp. 6790-806. Date of Electronic Publication: 2014 Sep 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Anti-Retroviral Agents/*therapeutic use
Histone Deacetylase Inhibitors/*therapeutic use
Hydroxamic Acids/*therapeutic use
Simian Acquired Immunodeficiency Syndrome/*drug therapy
Simian Immunodeficiency Virus/*drug effects
Acetylation/drug effects ; Animals ; CD4-Positive T-Lymphocytes/drug effects ; Disease Models, Animal ; Drug Therapy, Combination ; Histones/metabolism ; Macaca mulatta ; RNA, Viral/blood ; RNA, Viral/genetics ; Simian Acquired Immunodeficiency Syndrome/virology ; Viral Load/drug effects ; Vorinostat
Czasopismo naukowe
Tytuł :
Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins.
Autorzy :
Del Prete GQ; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Ailers B; Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA.
Moldt B; Department of Immunology and Microbiology, International AIDS Vaccine Initiative Neutralizing Antibody Center and Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
Keele BF; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Estes JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Rodriguez A; Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA.
Sampias M; Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA.
Oswald K; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Fast R; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Trubey CM; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Chertova E; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
Smedley J; Laboratory Animal Sciences Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Burton DR; Department of Immunology and Microbiology, International AIDS Vaccine Initiative Neutralizing Antibody Center and Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Shaw GM; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Markowitz M; Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA.
Piatak M Jr; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA.
KewalRamani VN; HIV Drug Resistance Program, National Cancer Institute, Frederick, MD 21702, USA.
Bieniasz PD; Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA; Laboratory of Retrovirology and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10016, USA.
Lifson JD; AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702, USA. Electronic address: .
Hatziioannou T; Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY 10016, USA. Electronic address: .
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Źródło :
Cell host & microbe [Cell Host Microbe] 2014 Sep 10; Vol. 16 (3), pp. 412-8.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
HIV Infections/*virology
HIV-1/*genetics
Simian Acquired Immunodeficiency Syndrome/*virology
Simian Immunodeficiency Virus/*genetics
env Gene Products, Human Immunodeficiency Virus/*genetics
Animals ; Antibodies, Neutralizing/immunology ; Disease Models, Animal ; Gene Expression ; HIV Antibodies/immunology ; HIV Infections/immunology ; HIV Infections/transmission ; HIV-1/metabolism ; Humans ; Macaca ; Simian Acquired Immunodeficiency Syndrome/immunology ; Simian Acquired Immunodeficiency Syndrome/transmission ; Simian Immunodeficiency Virus/metabolism ; Simian Immunodeficiency Virus/pathogenicity ; Virus Cultivation ; env Gene Products, Human Immunodeficiency Virus/metabolism
Czasopismo naukowe
    Wyświetlanie 1-5 z 5

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