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Wyszukujesz frazę ""Fatty acid"" wg kryterium: Temat


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Tytuł :
Fatty acid synthase inhibition ameliorates diabetes induced liver injury in rodent experimental model.
Autorzy :
Bedi O; Chitkara College of Pharmacy, Chitkara University, Punjab, India; Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India.
Srivastava N; Department of Dermatology, Venereology and Leprosy, PGIMER, Chandigarh, India.
Parsad D; Department of Dermatology, Venereology and Leprosy, PGIMER, Chandigarh, India.
Krishan P; Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Jun 15; Vol. 901, pp. 174078. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Complications/*drug therapy
Enzyme Inhibitors/*therapeutic use
Fatty Acid Synthase, Type I/*antagonists & inhibitors
Liver Diseases/*prevention & control
Animals ; Anthraquinones/therapeutic use ; Antioxidants/metabolism ; Arbutin/therapeutic use ; Blood Glucose/metabolism ; Diabetes Mellitus, Experimental/complications ; Diabetes Mellitus, Experimental/drug therapy ; Diet, High-Fat ; Fatty Acid Synthase, Type I/biosynthesis ; Fatty Acid Synthase, Type I/genetics ; Lipid Metabolism/drug effects ; Lipid Peroxidation/drug effects ; Liver Diseases/etiology ; Male ; Rats ; Rats, Wistar ; Signal Transduction/drug effects ; Stilbenes/therapeutic use
Czasopismo naukowe
Tytuł :
Exosomes isolated from the miR-215-modified bone marrow mesenchymal stem cells protect H 2 O 2 -induced rat myoblasts via the miR-215/FABP3 pathway.
Autorzy :
Zhou Q; Physical Education Department, Hohai University, Nanjing, Jiangsu 210098, China.
Yang H; Physical Education Department, Hohai University, Nanjing, Jiangsu 210098, China. Electronic address: .
Pan H; Department of food and drug, college of material and chemical engineering, Tongren University, Tongren, Guizhou 554300, China.
Pan H; Physical Education Department, Hohai University, Nanjing, Jiangsu 210098, China.
Zhou J; Department of clinical medicine, Jiangsu Health Vocational College, Nanjing, Jiangsu 211800, China.
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Źródło :
Experimental and molecular pathology [Exp Mol Pathol] 2021 Apr; Vol. 119, pp. 104608. Date of Electronic Publication: 2021 Jan 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytoprotection*/drug effects
Exosomes/*metabolism
Fatty Acid Binding Protein 3/*metabolism
Hydrogen Peroxide/*toxicity
Mesenchymal Stem Cells/*metabolism
MicroRNAs/*metabolism
Myoblasts/*metabolism
3' Untranslated Regions/genetics ; Animals ; Apoptosis/drug effects ; Apoptosis/genetics ; Base Sequence ; Cell Survival/drug effects ; Cell Survival/genetics ; Exosomes/drug effects ; Exosomes/ultrastructure ; Fatty Acid Binding Protein 3/genetics ; Gene Expression Regulation/drug effects ; Mesenchymal Stem Cells/drug effects ; MicroRNAs/genetics ; Myoblasts/drug effects ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Biosynthesis of Long-Chain Polyunsaturated Fatty Acids in Marine Gammarids: Molecular Cloning and Functional Characterisation of Three Fatty Acyl Elongases.
Autorzy :
Ribes-Navarro A; Instituto de Acuicultura de Torre de la Sal (IATS-CSIC), 12595 Ribera de Cabanes, Castellón, Spain.
Navarro JC; Instituto de Acuicultura de Torre de la Sal (IATS-CSIC), 12595 Ribera de Cabanes, Castellón, Spain.
Hontoria F; Instituto de Acuicultura de Torre de la Sal (IATS-CSIC), 12595 Ribera de Cabanes, Castellón, Spain.
Kabeya N; Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan.
Standal IB; Department of Fisheries and New Biomarine Industry, SINTEF Ocean, 7010 Trondheim, Norway.
Evjemo JO; Department of Fisheries and New Biomarine Industry, SINTEF Ocean, 7010 Trondheim, Norway.
Monroig Ó; Instituto de Acuicultura de Torre de la Sal (IATS-CSIC), 12595 Ribera de Cabanes, Castellón, Spain.
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Źródło :
Marine drugs [Mar Drugs] 2021 Apr 16; Vol. 19 (4). Date of Electronic Publication: 2021 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
Cloning, Molecular*
Amphipoda/*enzymology
Fatty Acid Elongases/*metabolism
Fatty Acids, Unsaturated/*biosynthesis
Amphipoda/genetics ; Animals ; Evolution, Molecular ; Fatty Acid Elongases/genetics ; Gene Expression Regulation, Enzymologic ; Phylogeny ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Comparison of the seed nutritional composition between conventional varieties and transgenic soybean overexpressing Physaria FAD3-1.
Autorzy :
Kim EH; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
Oh SW; R&D Coordination Division, Rural Development Administration, Jeonju, South Korea.
Lee SY; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
Park HY; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
Kang YY; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
Lee GM; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
Baek DY; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
Kang HJ; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
Park SY; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
Ryu TH; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
Chung YS; Department of Molecular Genetic Engineering, Dong-A University, Busan, South Korea.
Lee SG; Biosafety Division, National Institute of Agricultural Sciences, Jeonju, South Korea.
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Źródło :
Journal of the science of food and agriculture [J Sci Food Agric] 2021 Apr; Vol. 101 (6), pp. 2601-2613. Date of Electronic Publication: 2021 Jan 18.
Typ publikacji :
Journal Article
MeSH Terms :
Brassicaceae/*enzymology
Fatty Acid Desaturases/*genetics
Plant Proteins/*genetics
Plants, Genetically Modified/*chemistry
Soybeans/*chemistry
Soybeans/*genetics
Amino Acids/analysis ; Amino Acids/metabolism ; Brassicaceae/genetics ; Brassicaceae/metabolism ; Fatty Acid Desaturases/metabolism ; Fatty Acids/analysis ; Fatty Acids/metabolism ; Minerals/analysis ; Minerals/metabolism ; Nutritive Value ; Plant Proteins/metabolism ; Plants, Genetically Modified/genetics ; Plants, Genetically Modified/metabolism ; Republic of Korea ; Soybeans/classification ; Soybeans/metabolism
Czasopismo naukowe
Tytuł :
Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer.
Autorzy :
Grunt TW; Cell Signaling and Metabolism Networks Program, Division of Oncology, Department of Medicine I, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. .; Comprehensive Cancer Center, Vienna, Austria. .; Ludwig Boltzmann Institute for Hematology and Oncology, Vienna, Austria. .
Slany A; Department of Analytical Chemistry, University of Vienna, Vienna, Austria.
Semkova M; Department of Analytical Chemistry, University of Vienna, Vienna, Austria.
Colomer R; Department of Medical Oncology, Hospital Universitario La Princesa and Spanish National Cancer Research Centre (CNIO), Clinical Research Program, Madrid, Spain.
López-Rodríguez ML; Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Madrid, Spain.
Wuczkowski M; Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Wagner R; Cell Signaling and Metabolism Networks Program, Division of Oncology, Department of Medicine I, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Comprehensive Cancer Center, Vienna, Austria.
Gerner C; Department of Analytical Chemistry, University of Vienna, Vienna, Austria.
Stübiger G; Comprehensive Cancer Center, Vienna, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 10; Vol. 10 (1), pp. 14877. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Membrane/*drug effects
Fatty Acid Synthase, Type I/*antagonists & inhibitors
Gallic Acid/*analogs & derivatives
Lipidomics/*methods
Naphthalenes/*pharmacology
Ovarian Neoplasms/*drug therapy
Proteome/*metabolism
Cell Line, Tumor ; Cell Membrane/chemistry ; Cell Membrane/metabolism ; Cell Proliferation ; Drug Resistance, Neoplasm ; Fatty Acid Synthase, Type I/metabolism ; Fatty Acid Synthesis Inhibitors/pharmacology ; Female ; Gallic Acid/pharmacology ; Humans ; Metabolome ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Differences in erythrocyte phospholipid membrane long-chain polyunsaturated fatty acids and the prevalence of fatty acid desaturase genotype among African Americans and European Americans.
Autorzy :
Rifkin SB; Division of Gastroenterology and Hepatology, University of Michigan School of Medicine, 1150 W. Medical Center Drive, 6520 MSRB1, Ann Arbor, Michigan, United States. Electronic address: .
Shrubsole MJ; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Division of Epidemiology, Vanderbilt University School of Medicine, United States; Geriatrics Research, Education and Clinical Center (GRECC), Department of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN, United States.
Cai Q; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Division of Epidemiology, Vanderbilt University School of Medicine, United States.
Smalley WE; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Division of Gastroenterology, Vanderbilt University School of Medicine, United States.
Ness RM; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Division of Gastroenterology, Vanderbilt University School of Medicine, United States.
Swift LL; Department of Pathology, Microbiology and Immunology, Vanderbilt University, United States.
Milne G; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Division of Clinical Pharmacology, Vanderbilt University School of Medicine, United States.
Zheng W; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Division of Epidemiology, Vanderbilt University School of Medicine, United States; Geriatrics Research, Education and Clinical Center (GRECC), Department of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN, United States.
Murff HJ; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States; Geriatrics Research, Education and Clinical Center (GRECC), Department of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN, United States; Division of General Internal Medicine and Public Health, Vanderbilt University Medical Center, United States.
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Źródło :
Prostaglandins, leukotrienes, and essential fatty acids [Prostaglandins Leukot Essent Fatty Acids] 2021 Jan; Vol. 164, pp. 102216. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Erythrocyte Membrane*/genetics
Erythrocyte Membrane*/metabolism
Fatty Acid Desaturases*/genetics
Fatty Acid Desaturases*/metabolism
Fatty Acids, Unsaturated*/genetics
Fatty Acids, Unsaturated*/metabolism
Phospholipids*/genetics
Phospholipids*/metabolism
Polymorphism, Single Nucleotide*
African Americans/*genetics
European Continental Ancestry Group/*genetics
Female ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Production of branched-chain very-long-chain fatty acids by fatty acid elongases and their tissue distribution in mammals.
Autorzy :
Tanno H; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Sassa T; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. Electronic address: .
Sawai M; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Kihara A; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Jan; Vol. 1866 (1), pp. 158842. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acyl Coenzyme A/*metabolism
Amino Acids, Branched-Chain/*metabolism
Fatty Acid Elongases/*metabolism
Meibomian Glands/*metabolism
Acyltransferases/genetics ; Acyltransferases/metabolism ; Aldehyde Oxidoreductases/genetics ; Aldehyde Oxidoreductases/metabolism ; Amino Acids, Branched-Chain/classification ; Animals ; Ceramides/classification ; Ceramides/metabolism ; Cholesterol Esters/classification ; Cholesterol Esters/metabolism ; Fatty Acid Elongases/genetics ; Gene Expression Regulation ; HEK293 Cells ; Humans ; Lipidomics/methods ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Skin/metabolism ; Sterol O-Acyltransferase/genetics ; Sterol O-Acyltransferase/metabolism ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Thermal Shift Assay for Exploring Interactions Between Fatty Acid-Binding Protein and Inhibitors.
Autorzy :
Hao J; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2261, pp. 395-409.
Typ publikacji :
Journal Article
MeSH Terms :
Fatty Acid-Binding Proteins/*metabolism
Fluorescent Dyes/*metabolism
Real-Time Polymerase Chain Reaction/*instrumentation
Antineoplastic Agents/pharmacology ; Cell Line ; Fatty Acid-Binding Proteins/antagonists & inhibitors ; Fatty Acid-Binding Proteins/chemistry ; Humans ; Ligands ; Protein Binding ; Protein Folding ; Protein Stability ; Recombinant Proteins/metabolism ; Transition Temperature
Czasopismo naukowe
Tytuł :
Genetic inhibition of FABP4 attenuated endoplasmic reticulum stress and mitochondrial dysfunction in rhabdomyolysis-induced acute kidney injury.
Autorzy :
Liu J; Division of Nephrology and National Clinical Research Center for Geriatrics, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China.
Huang R; Division of Nephrology and National Clinical Research Center for Geriatrics, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China.
Li X; Division of Nephrology and National Clinical Research Center for Geriatrics, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China.
Guo F; Division of Nephrology and National Clinical Research Center for Geriatrics, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China.
Li L; Division of Nephrology and National Clinical Research Center for Geriatrics, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China.
Zeng X; West China Biomedical Big Data Center, West China Hospital of Sichuan University, Chengdu 610041, China.
Ma L; Division of Nephrology and National Clinical Research Center for Geriatrics, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China. Electronic address: .
Fu P; Division of Nephrology and National Clinical Research Center for Geriatrics, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China.
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Źródło :
Life sciences [Life Sci] 2021 Mar 01; Vol. 268, pp. 119023. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Kidney Injury/*etiology
Endoplasmic Reticulum Stress/*genetics
Fatty Acid-Binding Proteins/*genetics
Mitochondria/*pathology
Rhabdomyolysis/*pathology
Activating Transcription Factor 6/genetics ; Activating Transcription Factor 6/metabolism ; Acute Kidney Injury/pathology ; Animals ; Apoptosis/genetics ; Fatty Acid-Binding Proteins/metabolism ; Kidney/pathology ; Kidney/physiology ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/genetics ; Nephritis/genetics ; Nephritis/pathology ; Protein-Serine-Threonine Kinases/genetics ; Protein-Serine-Threonine Kinases/metabolism ; eIF-2 Kinase/genetics ; eIF-2 Kinase/metabolism
Czasopismo naukowe
Tytuł :
Biosynthesis of LC-PUFAs and VLC-PUFAs in Pampus argenteus : Characterization of Elovl4 Elongases and Regulation under Acute Salinity.
Autorzy :
Luo J; Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China.
Monroig Ó; Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes 12595, Castellón, Spain.
Liao K; School of Marine Sciences, Ningbo University, Ningbo 315211, China.
Ribes-Navarro A; Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes 12595, Castellón, Spain.
Navarro JC; Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes 12595, Castellón, Spain.
Zhu T; Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China.
Li J; School of Marine Sciences, Ningbo University, Ningbo 315211, China.
Xue L; School of Marine Sciences, Ningbo University, Ningbo 315211, China.
Zhou Q; Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China.
Jin M; Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Jan 27; Vol. 69 (3), pp. 932-944. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article
MeSH Terms :
Fatty Acid Elongases/*metabolism
Fatty Acids, Unsaturated/*biosynthesis
Fish Proteins/*metabolism
Fishes/*metabolism
Sodium Chloride/*metabolism
Amino Acid Sequence ; Animals ; Fatty Acid Elongases/chemistry ; Fatty Acid Elongases/genetics ; Fatty Acids, Unsaturated/chemistry ; Fish Proteins/chemistry ; Fish Proteins/genetics ; Fishes/classification ; Fishes/genetics ; Phylogeny ; Salinity ; Sequence Alignment
Czasopismo naukowe
Tytuł :
Crucial Role of FABP3 in αSyn-Induced Reduction of Septal GABAergic Neurons and Cognitive Decline in Mice.
Autorzy :
Matsuo K; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Yabuki Y; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.; Department of Genomic Neurology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan.
Melki R; Laboratory of Neurodegenerative Diseases, CEA, Institut François Jacob (MIRcen) and CNRS, 18 Route du Panorama, 92265 Fontenay-aux-Roses, France.
Bousset L; Laboratory of Neurodegenerative Diseases, CEA, Institut François Jacob (MIRcen) and CNRS, 18 Route du Panorama, 92265 Fontenay-aux-Roses, France.
Owada Y; Department of Organ Anatomy, Graduate School of Medicine, Tohoku University, Sendai 980-0872, Japan.
Fukunaga K; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 01; Vol. 22 (1). Date of Electronic Publication: 2021 Jan 01.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroprotection*
Cognitive Dysfunction/*etiology
Fatty Acid Binding Protein 3/*metabolism
GABAergic Neurons/*metabolism
Synucleinopathies/*complications
Animals ; Cognitive Dysfunction/physiopathology ; Cognitive Dysfunction/prevention & control ; Fatty Acid Binding Protein 3/physiology ; GABAergic Neurons/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Synucleinopathies/physiopathology ; alpha-Synuclein
Czasopismo naukowe
Tytuł :
Mitochondrial Fatty Acid Synthase Utilizes Multiple Acyl Carrier Protein Isoforms.
Autorzy :
Fu X; Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011.; Center for Biorenewable Chemicals (CBiRC), Iowa State University, Ames, Iowa 50011.; Center for Metabolic Biology, Iowa State University, Ames, Iowa 50011.
Guan X; Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011.; Center for Biorenewable Chemicals (CBiRC), Iowa State University, Ames, Iowa 50011.; Center for Metabolic Biology, Iowa State University, Ames, Iowa 50011.
Garlock R; Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011.
Nikolau BJ; Roy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011 .; Center for Biorenewable Chemicals (CBiRC), Iowa State University, Ames, Iowa 50011.; Center for Metabolic Biology, Iowa State University, Ames, Iowa 50011.
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Źródło :
Plant physiology [Plant Physiol] 2020 Jun; Vol. 183 (2), pp. 547-557. Date of Electronic Publication: 2020 Feb 24.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Acyl Carrier Protein/*metabolism
Fatty Acid Synthases/*metabolism
Protein Isoforms/*metabolism
Acyl Carrier Protein/genetics ; Arabidopsis/genetics ; Arabidopsis/metabolism ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Fatty Acid Synthase, Type II ; Fatty Acid Synthases/genetics ; Mitochondria/metabolism ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Multienzyme Complexes/genetics ; Multienzyme Complexes/metabolism ; Protein Binding ; Protein Isoforms/genetics
Czasopismo naukowe
Tytuł :
Novel carfilzomib-based combinations as potential therapeutic strategies for liposarcomas.
Autorzy :
Jeitany M; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. .; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. .
Prabhu A; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Dakle P; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Pathak E; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Madan V; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Kanojia D; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Mukundan V; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Jiang YY; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Landesman Y; Karyopharm Therapeutics, Newton, MA, USA.
Tam WL; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Kappei D; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Koeffler HP; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Cedars-Sinai Medical Center, Division of Hematology/Oncology, UCLA School of Medicine, Los Angeles, CA, USA.; Department of Hematology-Oncology, National University Cancer Institute of Singapore (NCIS), National University Hospital, Singapore, Singapore.
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Feb; Vol. 78 (4), pp. 1837-1851. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Fatty Acid Desaturases/*genetics
Karyopherins/*genetics
Liposarcoma/*drug therapy
Oligopeptides/*pharmacology
Receptors, Cytoplasmic and Nuclear/*genetics
Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Bortezomib/pharmacology ; Cell Line, Tumor ; Cell Nucleus/drug effects ; Drug Resistance, Neoplasm/genetics ; Drug Synergism ; Fatty Acid Desaturases/antagonists & inhibitors ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Hydrazines/pharmacology ; Liposarcoma/genetics ; Liposarcoma/pathology ; Piperazines/pharmacology ; Proteasome Endopeptidase Complex/drug effects ; Proteasome Inhibitors/pharmacology ; Triazoles/pharmacology
Czasopismo naukowe
Tytuł :
Is There a FADS2-Modulated Link between Long-Chain Polyunsaturated Fatty Acids in Plasma Phospholipids and Polyphenol Intake in Adult Subjects Who Are Overweight?
Autorzy :
Zec MM; Center of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
Krga I; Center of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
Stojković L; Laboratory for Radiobiology and Molecular Genetics, Vinča Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
Živković M; Laboratory for Radiobiology and Molecular Genetics, Vinča Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
Pokimica B; Center of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
Stanković A; Laboratory for Radiobiology and Molecular Genetics, Vinča Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
Glibetic M; Center of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.
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Źródło :
Nutrients [Nutrients] 2021 Jan 21; Vol. 13 (2). Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article
MeSH Terms :
Fatty Acid Desaturases/*metabolism
Fatty Acids/*metabolism
Overweight/*metabolism
Phospholipids/*administration & dosage
Plasma/*metabolism
Polyphenols/*administration & dosage
Adult ; Alleles ; Body Weight ; Eating ; Eicosapentaenoic Acid ; Fatty Acid Desaturases/genetics ; Female ; Gallic Acid ; Genotype ; Humans ; Male ; Middle Aged ; Obesity/genetics ; Obesity/metabolism ; Overweight/blood ; Overweight/genetics ; Photinia
Czasopismo naukowe
Tytuł :
In Silico Identification of Novel Interactions for FABP5 (Fatty Acid-Binding Protein 5) with Nutraceuticals: Possible Repurposing Approach.
Autorzy :
Cabezas R; Department of Physiology, School of Medicine, Universidad Antonio Nariño, Bogotá, Colombia.
Sahebkar A; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.; Polish Mother's Memorial Hospital Research Institute (PMMHRI), Lodz, Poland.
Echeverria V; Research and Development Department, Bay Pines VA Healthcare System, Bay Pines, FL, USA.
Santos JG; Departamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
Ashraf GM; King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Barreto GE; Department of Biological Sciences, University of Limerick, Limerick, Ireland. .; Health Research Institute, University of Limerick, Limerick, Ireland. .
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 1308, pp. 589-599.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents*
Fatty Acid-Binding Proteins*/genetics
Dietary Supplements ; Ligands ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł :
Delta or Omega? Δ12 (ω6) fatty acid desaturases count 3C after the pre-existing double bond.
Autorzy :
Starikov AY; K.A. Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya Street 35, Moscow, 127276, Russian Federation.
Sidorov RA; K.A. Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya Street 35, Moscow, 127276, Russian Federation.
Mironov KS; K.A. Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya Street 35, Moscow, 127276, Russian Federation.
Goriainov SV; Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya Street, Build. 6, Moscow, 117198, Russian Federation.
Los DA; K.A. Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya Street 35, Moscow, 127276, Russian Federation. Electronic address: .
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Źródło :
Biochimie [Biochimie] 2020 Dec; Vol. 179, pp. 46-53. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article
MeSH Terms :
Carbon/*chemistry
Fatty Acid Desaturases/*chemistry
Fatty Acid Desaturases/*supply & distribution
Fatty Acids, Monounsaturated/*chemistry
Carbon/metabolism ; Cyanobacteria/chemistry ; Cyanobacteria/enzymology ; Fatty Acid Desaturases/genetics ; Fatty Acid Desaturases/metabolism ; Fatty Acids, Monounsaturated/isolation & purification ; Fatty Acids, Monounsaturated/metabolism ; Galactolipids/analysis ; Glycolipids/analysis ; Lipid Metabolism ; Phosphatidylglycerols/analysis ; Spectrometry, Mass, Electrospray Ionization ; Synechococcus/chemistry ; Synechococcus/enzymology ; Synechocystis/chemistry ; Synechocystis/enzymology
SCR Organism :
Gloeobacter violaceus; Synechococcus elongatus
Czasopismo naukowe
Tytuł :
[Transgenesis of Drosophila melanogaster with an Elovl5 gene enables the production of longer-chain fatty acids].
Autorzy :
Wang L; School of Biology and Engineering, Guizhou Medical University, Guiyang 550025, Guizhou, China.
Tang Q; School of Biology and Engineering, Guizhou Medical University, Guiyang 550025, Guizhou, China.
He Y; School of Biology and Engineering, Guizhou Medical University, Guiyang 550025, Guizhou, China.
Wang Y; School of Biology and Engineering, Guizhou Medical University, Guiyang 550025, Guizhou, China.
Yang S; School of Biology and Engineering, Guizhou Medical University, Guiyang 550025, Guizhou, China.
Zhu G; School of Biology and Engineering, Guizhou Medical University, Guiyang 550025, Guizhou, China.
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Źródło :
Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2020 Oct 25; Vol. 36 (10), pp. 2171-2180.
Typ publikacji :
Journal Article
MeSH Terms :
Acetyltransferases*/genetics
Drosophila melanogaster*/genetics
Fatty Acid Elongases*/genetics
Fatty Acid Elongases*/metabolism
Fatty Acids*/biosynthesis
Fatty Acids*/genetics
Animals ; Gene Transfer Techniques ; Mice
Czasopismo naukowe
Tytuł :
Lactate and intestinal fatty acid binding protein as essential biomarkers in neonates with necrotizing enterocolitis: ultrasonographic and surgical considerations.
Autorzy :
El-Abd Ahmed A; Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, Egypt.
Hassan MH; Department of Medical Biochemistry, Faculty of Medicine, South Valley University, Qena, Egypt. Electronic address: .
Abo-Halawa N; Department of Pediatric Surgery, Pediatric Surgery Unit, Faculty of Medicine, South Valley University, Qena, Egypt.
Abdel-Razik GM; Department of Diagnostic Radiology, Faculty of Medicine, South Valley University, Qena, Egypt.
Moubarak FA; Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, Egypt.
Sakhr HM; Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, Egypt.
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Źródło :
Pediatrics and neonatology [Pediatr Neonatol] 2020 Oct; Vol. 61 (5), pp. 481-489. Date of Electronic Publication: 2020 Apr 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enterocolitis, Necrotizing/*diagnosis
Fatty Acid-Binding Proteins/*analysis
Lactic Acid/*blood
Biomarkers/analysis ; Enterocolitis, Necrotizing/metabolism ; Enterocolitis, Necrotizing/surgery ; Fatty Acid-Binding Proteins/blood ; Fatty Acid-Binding Proteins/urine ; Female ; Humans ; Infant, Newborn ; Male ; Ultrasonography
Czasopismo naukowe
Tytuł :
Role of Gal-3 and H-FABP in the early diagnosis of acute coronary syndrome.
Autorzy :
Atay E
Guzel M
Amanvermez R
Demir MT
Erenler AK
Ozgen E
Yucel M
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Źródło :
Bratislavske lekarske listy [Bratisl Lek Listy] 2019; Vol. 120 (2), pp. 124-130.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Coronary Syndrome*/blood
Acute Coronary Syndrome*/diagnosis
Biomarkers*/analysis
Biomarkers*/blood
Fatty Acid Binding Protein 3*/blood
Transcription Factors*/blood
Adult ; Early Diagnosis ; Fatty Acid-Binding Proteins ; Humans ; Sensitivity and Specificity ; Troponin I
Czasopismo naukowe
Tytuł :
Δ6 fatty acid desaturases in polyunsaturated fatty acid biosynthesis: insights into the evolution, function with substrate specificities and biotechnological use.
Autorzy :
Cui J; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.; School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.
Chen H; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China. .; School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China. .
Tang X; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.; School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.
Zhao J; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.; School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.
Zhang H; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.; School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, 214122, People's Republic of China.; Wuxi Translational Medicine Research Center and Jiangsu Translational Medicine Research Institute Wuxi Branch, Wuxi, 214122, People's Republic of China.
Chen YQ; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.; School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.; Department of Cancer Biology, Wake Forest School of Medicine, 5, Winston-Salem, NC, 27127, USA.
Chen W; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.; School of Food Science and Technology, Jiangnan University, Wuxi, 214122, People's Republic of China.; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, 214122, People's Republic of China.; Beijing Innovation Center of Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), Beijing, 100048, People's Republic of China.
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Źródło :
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2020 Dec; Vol. 104 (23), pp. 9947-9963. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Fatty Acid Desaturases*/genetics
Fatty Acid Desaturases*/metabolism
Fatty Acids, Omega-3*
Fatty Acids, Unsaturated ; Linoleic Acid ; Substrate Specificity
Czasopismo naukowe

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