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Tytuł:
FHOD1 is upregulated in glioma cells and attenuates ferroptosis of glioma cells by targeting HSPB1 signaling.
Autorzy:
Zhang F; Department of Gynecology, Xiangya Hospital, Central South University, Changsha, China.; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, China.
Wu L; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, China.
Feng S; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Zhao Z; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
Zhang K; State Key Laboratory of Silkworm Genome Biology, Medical Research Institute, Southwest University, Chongqing, China.
Thakur A; Pritzker School of Molecular Engineering, Ben May Department for Cancer Research, University of Chicago, Chicago, Illinois, USA.
Xu Z; Department of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Liang Q; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.
Liu Y; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.
Liu W; Department of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Yan Y; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 Nov; Vol. 29 (11), pp. 3351-3363. Date of Electronic Publication: 2023 May 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ferroptosis*
Glioma*/metabolism
Humans ; Proteomics ; Signal Transduction ; Heat-Shock Proteins/genetics ; Heat-Shock Proteins/metabolism ; Formins/metabolism ; Fetal Proteins/genetics ; Fetal Proteins/metabolism ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism
Czasopismo naukowe
Tytuł:
ALCAM/CD166 Is Involved in the Binding and Uptake of Cancer-Derived Extracellular Vesicles.
Autorzy:
Cardeñes B; Centre for Molecular Biology 'Severo Ochoa' (CSIC-UAM), Cell-Cell Communication & Inflammation Unit, 28049 Madrid, Spain.
Clares I; Centre for Molecular Biology 'Severo Ochoa' (CSIC-UAM), Cell-Cell Communication & Inflammation Unit, 28049 Madrid, Spain.
Bezos T; Centre for Molecular Biology 'Severo Ochoa' (CSIC-UAM), Cell-Cell Communication & Inflammation Unit, 28049 Madrid, Spain.
Toribio V; Centre for Molecular Biology 'Severo Ochoa' (CSIC-UAM), Cell-Cell Communication & Inflammation Unit, 28049 Madrid, Spain.; Department of Molecular Biology, Faculty of Sciences, Instituto Universitario de Biología Molecular, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
López-Martín S; Centre for Molecular Biology 'Severo Ochoa' (CSIC-UAM), Cell-Cell Communication & Inflammation Unit, 28049 Madrid, Spain.; Department of Molecular Biology, Faculty of Sciences, Instituto Universitario de Biología Molecular, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Rocha A; Centre for Molecular Biology 'Severo Ochoa' (CSIC-UAM), Cell-Cell Communication & Inflammation Unit, 28049 Madrid, Spain.
Peinado H; Microenvironment and Metastasis Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Center (CNIO), 28029 Madrid, Spain.
Yáñez-Mó M; Centre for Molecular Biology 'Severo Ochoa' (CSIC-UAM), Cell-Cell Communication & Inflammation Unit, 28049 Madrid, Spain.; Department of Molecular Biology, Faculty of Sciences, Instituto Universitario de Biología Molecular, Universidad Autónoma de Madrid, 28049 Madrid, Spain.; Instituto de Investigación Sanitaria Hospital La Princesa, 28006 Madrid, Spain.
Cabañas C; Centre for Molecular Biology 'Severo Ochoa' (CSIC-UAM), Cell-Cell Communication & Inflammation Unit, 28049 Madrid, Spain.; Department of Immunology, Ophthalmology and Otorhinolaryngology, School of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain.; Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12), 28041 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 20; Vol. 23 (10). Date of Electronic Publication: 2022 May 20.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma*/pathology
Antigens, CD*/metabolism
Cell Adhesion Molecules, Neuronal*/metabolism
Extracellular Vesicles*/metabolism
Fetal Proteins*/metabolism
Ovarian Neoplasms*/pathology
Peritoneal Neoplasms*/metabolism
Activated-Leukocyte Cell Adhesion Molecule/metabolism ; Carcinoma, Ovarian Epithelial/pathology ; Female ; Humans
Czasopismo naukowe
Tytuł:
The evolutionary history of Brachyury genes in Hydrozoa involves duplications, divergence, and neofunctionalization.
Autorzy:
Vetrova AA; Laboratory of Morphogenesis Evolution, Koltzov Institute of Developmental Biology RAS, Vavilova 26, Moscow, 119334, Russia.
Kupaeva DM; Department of Embryology, Faculty of Biology, Lomonosov Moscow State University, Leninskiye Gory 1/12, Moscow, 119234, Russia.
Kizenko A; Institute of Science and Technology Austria (ISTA), Am Campus 1, 3400, Klosterneuburg, Austria.
Lebedeva TS; Department for Molecular Evolution and Development, Centre of Organismal Systems Biology, University of Vienna, Althanstraße 14, 1090, Vienna, Austria.
Walentek P; Renal Division, Internal Medicine IV, Medical Center, Faculty of Medicine, University of Freiburg, 79106, Freiburg, Germany.; CIBSS-Centre for Integrative Biological Signalling Studies, University of Freiburg, 79104, Freiburg, Germany.
Tsikolia N; Institute of Anatomy and Embryology, University Medical Center Göttingen, Kreuzbergring 36, 37085, Göttingen, Germany.
Kremnyov SV; Laboratory of Morphogenesis Evolution, Koltzov Institute of Developmental Biology RAS, Vavilova 26, Moscow, 119334, Russia. .; Department of Embryology, Faculty of Biology, Lomonosov Moscow State University, Leninskiye Gory 1/12, Moscow, 119234, Russia. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 09; Vol. 13 (1), pp. 9382. Date of Electronic Publication: 2023 Jun 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hydrozoa*/genetics
Cnidaria*/genetics
Animals ; Phylogeny ; Biological Evolution ; Fetal Proteins/genetics ; Fetal Proteins/metabolism
Czasopismo naukowe
Tytuł:
Activated leukocyte cell adhesion molecule expression correlates with the WNT subgroup in medulloblastoma and is involved in regulating tumor cell proliferation and invasion.
Autorzy:
Achiha T; Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.
Kijima N; Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Osaka National Hospital, National Hospital Organization, Osaka, Japan.
Kodama Y; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Pathology and Applied Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Department of Central Laboratory and Surgical Pathology, Osaka National Hospital, National Hospital Organization, Osaka, Japan.
Kagawa N; Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.
Kinoshita M; Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.
Fujimoto Y; Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.
Nonaka M; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Osaka National Hospital, National Hospital Organization, Osaka, Japan.; Department of Neurosurgery, Kansai Medical University, Hirakata, Japan.
Fukai J; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurological Surgery, Wakayama Medical University School of Medicine, Wakayama, Japan.
Inoue A; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Ehime University School of Medicine, Ehime, Japan.
Nishida N; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan.
Yamanaka T; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Harada A; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Pediatric Neurosurgery, Takatsuki General Hospital, Osaka, Japan.
Mori K; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Kansai Rosai Hospital, Amagasaki, Japan.
Tsuyuguchi N; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Kindai University Faculty of Medicine, Sayama, Japan.
Uda T; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Ishibashi K; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Osaka City General Hospital, Osaka, Japan.
Tomogane Y; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Hyogo College of Medicine, Hyogo, Japan.
Sakamoto D; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Hyogo College of Medicine, Hyogo, Japan.
Shofuda T; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Biomedical Research and Innovation Research, Institute for Clinical Research, Osaka National Hospital, National Hospital Organization, Osaka, Japan.
Yoshioka E; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Biomedical Research and Innovation Research, Institute for Clinical Research, Osaka National Hospital, National Hospital Organization, Osaka, Japan.
Kanematsu D; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Biomedical Research and Innovation Research, Institute for Clinical Research, Osaka National Hospital, National Hospital Organization, Osaka, Japan.
Mano M; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Central Laboratory and Surgical Pathology, Osaka National Hospital, National Hospital Organization, Osaka, Japan.
Luu B; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Taylor MD; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Surgery, Department of Laboratory Medicine and Pathobiology, and Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Kanemura Y; Kansai Molecular Diagnosis Network for Central Nervous System Tumors, Osaka, Japan.; Department of Neurosurgery, Osaka National Hospital, National Hospital Organization, Osaka, Japan.; Department of Neurosurgery, Hyogo College of Medicine, Hyogo, Japan.
Kishima H; Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.
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Źródło:
PloS one [PLoS One] 2020 Dec 03; Vol. 15 (12), pp. e0243272. Date of Electronic Publication: 2020 Dec 03 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD/*metabolism
Cell Adhesion Molecules, Neuronal/*metabolism
Fetal Proteins/*metabolism
Medulloblastoma/*metabolism
Wnt Proteins/*metabolism
Activated-Leukocyte Cell Adhesion Molecule/genetics ; Adolescent ; Animals ; Antigens, CD/physiology ; Biomarkers, Tumor/metabolism ; Brain Neoplasms/genetics ; Cell Adhesion/genetics ; Cell Adhesion Molecules, Neuronal/physiology ; Cell Movement/genetics ; Cell Proliferation/genetics ; Cerebellar Neoplasms/genetics ; Child ; Child, Preschool ; Female ; Fetal Proteins/physiology ; Gene Expression/genetics ; Gene Expression Profiling ; Humans ; Infant ; Japan/epidemiology ; Male ; Medulloblastoma/physiopathology ; Mice ; Neoplasm Invasiveness ; RNA, Messenger/genetics ; Wnt Proteins/genetics ; Young Adult
Czasopismo naukowe
Tytuł:
Multiple formin proteins participate in glioblastoma migration.
Autorzy:
Heuser VD; Laboratory Division, Department of Pathology, Turku University Hospital, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.
Kiviniemi A; Department of Radiology, Turku University Hospital and University of Turku, Turku, Finland.
Lehtinen L; Laboratory Division, Department of Pathology, Turku University Hospital, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.
Munthe S; Department of Neurosurgery, Odense University Hospital, Odense, Denmark.
Kristensen BW; Department of Pathology and Department of Clinical Research, Odense University Hospital, Odense, Denmark.
Posti JP; Division of Clinical Neurosciences, Department of Neurosurgery and Turku Brain Injury Centre, Turku University Hospital, Turku, Finland.; Department of Clinical Neurosciences, University of Turku, Turku, Finland.
Sipilä JOT; Department of Neurology, Siun sote, North Karelia Central Hospital, Joensuu, Finland.; Division of Clinical Neurosciences, Department of Neurology, Turku University Hospital, Turku, Finland.; Department of Neurology, University of Turku, Turku, Finland.
Vuorinen V; Division of Clinical Neurosciences, Department of Neurosurgery, Turku University Hospital, Turku, Finland.
Carpén O; Institute of Biomedicine, University of Turku, Turku, Finland.; Department of Pathology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Gardberg M; Laboratory Division, Department of Pathology, Turku University Hospital, Turku, Finland. .; Institute of Biomedicine, University of Turku, Turku, Finland. .
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Źródło:
BMC cancer [BMC Cancer] 2020 Jul 29; Vol. 20 (1), pp. 710. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Movement*
Brain Neoplasms/*metabolism
Fetal Proteins/*metabolism
Formins/*metabolism
Glioblastoma/*metabolism
Actins/metabolism ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Fetal Proteins/genetics ; Formins/genetics ; Gene Knockdown Techniques ; Glioblastoma/pathology ; Humans ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł:
Anti-CD166/4-1BB chimeric antigen receptor T cell therapy for the treatment of osteosarcoma.
Autorzy:
Wang Y; Department of Orthopedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, #88 Jie Fang Road, Hangzhou, 310009, Zhejiang, People's Republic of China.; Orthopedics Research Institute of Zhejiang University, No. 88, Jiefang Road, Hangzhou, 310009, China.
Yu W; Department of Orthopedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, #88 Jie Fang Road, Hangzhou, 310009, Zhejiang, People's Republic of China.; Orthopedics Research Institute of Zhejiang University, No. 88, Jiefang Road, Hangzhou, 310009, China.
Zhu J; Department of Orthopedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, #88 Jie Fang Road, Hangzhou, 310009, Zhejiang, People's Republic of China.; Orthopedics Research Institute of Zhejiang University, No. 88, Jiefang Road, Hangzhou, 310009, China.
Wang J; Department of Orthopedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, #88 Jie Fang Road, Hangzhou, 310009, Zhejiang, People's Republic of China.; Orthopedics Research Institute of Zhejiang University, No. 88, Jiefang Road, Hangzhou, 310009, China.
Xia K; Department of Orthopedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, #88 Jie Fang Road, Hangzhou, 310009, Zhejiang, People's Republic of China.; Orthopedics Research Institute of Zhejiang University, No. 88, Jiefang Road, Hangzhou, 310009, China.
Liang C; Department of Orthopedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, #88 Jie Fang Road, Hangzhou, 310009, Zhejiang, People's Republic of China.; Orthopedics Research Institute of Zhejiang University, No. 88, Jiefang Road, Hangzhou, 310009, China.
Tao H; Department of Orthopedics, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, #88 Jie Fang Road, Hangzhou, 310009, Zhejiang, People's Republic of China. .; Orthopedics Research Institute of Zhejiang University, No. 88, Jiefang Road, Hangzhou, 310009, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2019 Apr 17; Vol. 38 (1), pp. 168. Date of Electronic Publication: 2019 Apr 17.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, CD/*administration & dosage
Cell Adhesion Molecules, Neuronal/*administration & dosage
Fetal Proteins/*administration & dosage
Immunotherapy, Adoptive/*methods
Osteosarcoma/*therapy
Receptors, Antigen, T-Cell/*immunology
Receptors, Chimeric Antigen/*immunology
4-1BB Ligand/administration & dosage ; 4-1BB Ligand/genetics ; 4-1BB Ligand/immunology ; Animals ; Antigens, CD/genetics ; Antigens, CD/immunology ; Cell Adhesion Molecules, Neuronal/genetics ; Cell Adhesion Molecules, Neuronal/immunology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Fetal Proteins/genetics ; Fetal Proteins/immunology ; Flow Cytometry ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Interleukin-15/immunology ; Interleukin-2/genetics ; Interleukin-2/immunology ; Mice ; Osteosarcoma/genetics ; Osteosarcoma/immunology ; Osteosarcoma/pathology ; Receptors, Antigen, T-Cell/administration & dosage ; Receptors, Antigen, T-Cell/genetics ; Receptors, Chimeric Antigen/administration & dosage ; Receptors, Chimeric Antigen/genetics ; Signal Transduction/immunology ; T-Lymphocytes/immunology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
CircMED12L Protects Against Hydrogen Peroxide-induced Apoptotic and Oxidative Injury in Human Lens Epithelial Cells by miR-34a-5p/ALCAM axis.
Autorzy:
Wu B; Department of Ophthalmology, Lanzhou Purui Ophthalmology Hospital, Lanzhou, China.
Sun Y; Department of Ophthalmology, Lanzhou Purui Ophthalmology Hospital, Lanzhou, China.; Department of Ophthalmology, Gansu Rehabilitation Center Hospital, Lanzhou, China.; Clinical School of Traditional Chinese, Gansu University of Chinese Medicine, Lanzhou, China.
Hou J; Department of Ophthalmology, Lanzhou Purui Ophthalmology Hospital, Lanzhou, China.; Department of Ophthalmology, Gansu Rehabilitation Center Hospital, Lanzhou, China.
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Źródło:
Current eye research [Curr Eye Res] 2022 Dec; Vol. 47 (12), pp. 1631-1640. Date of Electronic Publication: 2022 Oct 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cataract*/genetics
Cataract*/metabolism
MicroRNAs*/genetics
MicroRNAs*/pharmacology
Humans ; Hydrogen Peroxide/toxicity ; Hydrogen Peroxide/metabolism ; Activated-Leukocyte Cell Adhesion Molecule/metabolism ; Activated-Leukocyte Cell Adhesion Molecule/pharmacology ; Oxidative Stress ; Epithelial Cells/metabolism ; Apoptosis ; Fetal Proteins ; Antigens, CD/metabolism ; Cell Adhesion Molecules, Neuronal
Czasopismo naukowe
Tytuł:
MiR-148b suppressed non-small cell lung cancer progression via inhibiting ALCAM through the NF-κB signaling pathway.
Autorzy:
Jiang Z; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Heilongjiang, China.
Zhang J; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Heilongjiang, China.
Chen F; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Heilongjiang, China.
Sun Y; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Heilongjiang, China.
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Źródło:
Thoracic cancer [Thorac Cancer] 2020 Feb; Vol. 11 (2), pp. 415-425. Date of Electronic Publication: 2019 Dec 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Antigens, CD/*metabolism
Biomarkers, Tumor/*metabolism
Carcinoma, Non-Small-Cell Lung/*pathology
Cell Adhesion Molecules, Neuronal/*metabolism
Fetal Proteins/*metabolism
Lung Neoplasms/*pathology
MicroRNAs/*genetics
NF-kappa B/*metabolism
Antigens, CD/genetics ; Apoptosis ; Biomarkers, Tumor/genetics ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/metabolism ; Cell Adhesion Molecules, Neuronal/genetics ; Cell Movement ; Cell Proliferation ; Disease Progression ; Female ; Fetal Proteins/genetics ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Male ; Middle Aged ; NF-kappa B/genetics ; Prognosis ; Survival Rate ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
Protecting fetal development.
Autorzy:
Kellam P; Department of Medicine, Division of Infectious Diseases, Imperial College London, London, UK. .
Weiss RA; Division of Infection and Immunity, University College London, London, UK. .
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Źródło:
Science (New York, N.Y.) [Science] 2019 Jul 12; Vol. 365 (6449), pp. 118-119.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Fetal Proteins*
Trophoblasts*
Female ; Fetal Death ; Fetal Development ; Humans ; Placenta ; Pregnancy
Czasopismo naukowe
Tytuł:
Critical Role of CD6highCD4+ T Cells in Driving Th1/Th17 Cell Immune Responses and Mucosal Inflammation in IBD.
Autorzy:
Ma C; Department of Gastroenterology, The Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
Wu W; Department of Gastroenterology, The Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
Lin R; Department of Gastroenterology, The Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
Ge Y; Department of Gastroenterology, The Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
Zhang C; Department of Gastroenterology, The Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
Sun S; Department of Gastroenterology, Henan Provincial People's Hospital, Henan University School of Medicine, Zhengzhou, China.
Cong Y; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston TX, USA.
Li X; Department of Gastroenterology, Henan Provincial People's Hospital, Henan University School of Medicine, Zhengzhou, China.
Liu Z; Department of Gastroenterology, The Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
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Źródło:
Journal of Crohn's & colitis [J Crohns Colitis] 2019 Mar 30; Vol. 13 (4), pp. 510-524.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, CD/*metabolism
Antigens, Differentiation, T-Lymphocyte/*metabolism
CD4-Positive T-Lymphocytes/*metabolism
Cell Adhesion Molecules, Neuronal/*metabolism
Fetal Proteins/*metabolism
Inflammatory Bowel Diseases/*immunology
Inflammatory Bowel Diseases/*metabolism
Intestinal Mucosa/*immunology
Antigens, CD/genetics ; Antigens, Differentiation, T-Lymphocyte/genetics ; CD4-Positive T-Lymphocytes/physiology ; Case-Control Studies ; Cell Adhesion Molecules, Neuronal/genetics ; Cell Differentiation ; Fetal Proteins/genetics ; Humans ; Inflammatory Bowel Diseases/genetics ; Intestinal Mucosa/metabolism ; Lymphocyte Activation ; Severity of Illness Index ; Th1 Cells/immunology ; Th17 Cells/immunology
Czasopismo naukowe
Tytuł:
Clinicocytopathological spectrum, including uncommon forms, of nine cases of chordomas with immunohistochemical results, including brachyury immunostaining: A single institutional experience.
Autorzy:
Rekhi B; Department of Surgical Pathology, Tata Memorial Hospital, Mumbai, India.
Karmarkar S; Department of Surgical Pathology, Tata Memorial Hospital, Mumbai, India.
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Źródło:
Cytopathology : official journal of the British Society for Clinical Cytology [Cytopathology] 2019 Mar; Vol. 30 (2), pp. 229-235. Date of Electronic Publication: 2018 Nov 08.
Typ publikacji:
Journal Article
MeSH Terms:
Cytodiagnosis*
Chordoma/*diagnosis
Fetal Proteins/*isolation & purification
T-Box Domain Proteins/*isolation & purification
Adult ; Aged ; Biopsy, Fine-Needle ; Chordoma/genetics ; Chordoma/pathology ; Female ; Fetal Proteins/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Male ; Middle Aged ; Mucin-1/genetics ; T-Box Domain Proteins/genetics
Czasopismo naukowe
Tytuł:
Significant co-expression of putative cancer stem cell markers, EpCAM and CD166, correlates with tumor stage and invasive behavior in colorectal cancer.
Autorzy:
Kalantari E; Oncopathology Research Center, Iran University of Medical Sciences, Hemmat Street (Highway), Next to Milad Tower, Tehran, 14496-14530, Iran.
Taheri T; Department of Pathology, Iran University of Medical Sciences, Tehran, Iran.
Fata S; Department of Pathology, Iran University of Medical Sciences, Tehran, Iran.
Abolhasani M; Oncopathology Research Center, Iran University of Medical Sciences, Hemmat Street (Highway), Next to Milad Tower, Tehran, 14496-14530, Iran.; Department of Pathology, Hasheminejad kidney Center, Iran University of Medical Sciences, Tehran, Iran.
Mehrazma M; Oncopathology Research Center, Iran University of Medical Sciences, Hemmat Street (Highway), Next to Milad Tower, Tehran, 14496-14530, Iran.
Madjd Z; Oncopathology Research Center, Iran University of Medical Sciences, Hemmat Street (Highway), Next to Milad Tower, Tehran, 14496-14530, Iran. .; Department of Molecular Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran. .
Asgari M; Oncopathology Research Center, Iran University of Medical Sciences, Hemmat Street (Highway), Next to Milad Tower, Tehran, 14496-14530, Iran. mojgan_.; Department of Pathology, Hasheminejad kidney Center, Iran University of Medical Sciences, Tehran, Iran. mojgan_.
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Źródło:
World journal of surgical oncology [World J Surg Oncol] 2022 Jan 11; Vol. 20 (1), pp. 15. Date of Electronic Publication: 2022 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*
Antigens, CD/*genetics
Cell Adhesion Molecules, Neuronal/*genetics
Epithelial Cell Adhesion Molecule/*genetics
Fetal Proteins/*genetics
Biomarkers, Tumor ; Humans ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Neoplastic Stem Cells ; Prognosis
Czasopismo naukowe
Tytuł:
Loss of mDia1 and Fhod1 impacts platelet formation but not platelet function.
Autorzy:
Zuidscherwoude M; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.
Haining EJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Simms VA; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Watson S; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Grygielska B; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Hardy AT; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Bacon A; Genome Editing Facility, Technology Hub, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Watson SP; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.
Thomas SG; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK.
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Źródło:
Platelets [Platelets] 2021 Nov 17; Vol. 32 (8), pp. 1051-1062. Date of Electronic Publication: 2020 Sep 27.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelets/*metabolism
Fetal Proteins/*metabolism
Formins/*metabolism
Microtubules/*metabolism
Platelet Function Tests/*methods
Animals ; Disease Models, Animal ; Humans ; Mice ; Mice, Knockout
Czasopismo naukowe
Tytuł:
DNA methylation changes following narrative exposure therapy in a randomized controlled trial with female former child soldiers.
Autorzy:
Carleial S; Department of Psychology, Centre for Psychiatry, University of Konstanz, Feuerstein-Strasse. 55, Haus 22, 78479, Konstanz, Germany. .
Nätt D; Division of Neurobiology, Department of Biomedical and Clinical Sciences, University of Linköping, Building 463, Room 12.023, Linköping, Sweden.
Unternährer E; Department of Psychology, Centre for Psychiatry, University of Konstanz, Feuerstein-Strasse. 55, Haus 22, 78479, Konstanz, Germany.; Child- and Adolescent Research Department, Psychiatric University Hospitals Basel (UPK), University of Basel, Basel, Switzerland.
Elbert T; Department of Psychology, Centre for Psychiatry, University of Konstanz, Feuerstein-Strasse. 55, Haus 22, 78479, Konstanz, Germany.; Vivo International E.V., Postbox 5108, 78430, Konstanz, Germany.
Robjant K; Vivo International E.V., Postbox 5108, 78430, Konstanz, Germany.
Wilker S; Vivo International E.V., Postbox 5108, 78430, Konstanz, Germany.; Department of Psychology and Sports Science, University of Bielefeld, 33501, Bielefeld, Germany.
Vukojevic V; Psychiatric University Clinics, Transfaculty Research Platform, University of Basel, Wilhelm Klein-Strasse 27, CH-4012, Basel, Switzerland.
Kolassa IT; Vivo International E.V., Postbox 5108, 78430, Konstanz, Germany.; Department of Clinical and Biological Psychology, Institute of Psychology & Education, University of Ulm, Ulm University, Ulm, Germany.
Zeller AC; Department of Psychology, Centre for Psychiatry, University of Konstanz, Feuerstein-Strasse. 55, Haus 22, 78479, Konstanz, Germany.; Vivo International E.V., Postbox 5108, 78430, Konstanz, Germany.
Koebach A; Department of Psychology, Centre for Psychiatry, University of Konstanz, Feuerstein-Strasse. 55, Haus 22, 78479, Konstanz, Germany.; Vivo International E.V., Postbox 5108, 78430, Konstanz, Germany.
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Źródło:
Scientific reports [Sci Rep] 2021 Sep 16; Vol. 11 (1), pp. 18493. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Adverse Childhood Experiences*
DNA Methylation*
Implosive Therapy*
Stress Disorders, Post-Traumatic/*genetics
Adolescent ; Adult ; Aggression ; Antigens, CD/genetics ; Armed Conflicts ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules, Neuronal/genetics ; Child ; Democratic Republic of the Congo ; Female ; Fetal Proteins/genetics ; Humans ; Microfilament Proteins/genetics ; Stress Disorders, Post-Traumatic/therapy ; Sulfurtransferases/genetics
Czasopismo naukowe
Tytuł:
Aurora kinase A is essential for meiosis in mouse oocytes.
Autorzy:
Blengini CS; Department of Genetics; Rutgers, The State University of New Jersey, Piscataway, New Jersey, United States of America.; Human Genetics Institute of New Jersey; Piscataway, New Jersey, United States of America.
Ibrahimian P; Department of Genetics; Rutgers, The State University of New Jersey, Piscataway, New Jersey, United States of America.
Vaskovicova M; Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, Libechov, Czech Republic.
Drutovic D; Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, Libechov, Czech Republic.
Solc P; Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, Libechov, Czech Republic.
Schindler K; Department of Genetics; Rutgers, The State University of New Jersey, Piscataway, New Jersey, United States of America.; Human Genetics Institute of New Jersey; Piscataway, New Jersey, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2021 Apr 26; Vol. 17 (4), pp. e1009327. Date of Electronic Publication: 2021 Apr 26 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Aurora Kinase A/*genetics
Cell Cycle Proteins/*genetics
Fetal Proteins/*genetics
Meiosis/*genetics
Microtubule-Associated Proteins/*genetics
Oocytes/*growth & development
Protein Serine-Threonine Kinases/*genetics
Proto-Oncogene Proteins/*genetics
Animals ; Aurora Kinase B/genetics ; Aurora Kinase C/genetics ; Cell Nucleus Division/genetics ; Chromosome Segregation/genetics ; Female ; Gene Expression Regulation, Developmental/genetics ; Humans ; Mice ; Microtubule-Organizing Center/metabolism ; Oocytes/metabolism ; Spindle Apparatus/genetics ; Spindle Poles/genetics ; Polo-Like Kinase 1
Czasopismo naukowe
Tytuł:
Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos.
Autorzy:
Madissoon E; Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm, Sweden.
Jouhilahti EM; Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm, Sweden.
Vesterlund L; Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm, Sweden.
Töhönen V; Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm, Sweden.
Krjutškov K; Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Competence Centre on Health Technologies, Tartu, Estonia.
Petropoulos S; Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Huddinge, Stockholm, Sweden.
Einarsdottir E; Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Molecular Neurology Research Program, University of Helsinki and Folkhälsan Institute of Genetics, Helsinki, Finland.
Linnarsson S; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Lanner F; Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Huddinge, Stockholm, Sweden.
Månsson R; Department of Laboratory Medicine, Division of Clinical Immunology, Karolinska Institutet, Huddinge, Stockholm, Sweden.
Hovatta O; Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Huddinge, Stockholm, Sweden.
Bürglin TR; Department of Biomedicine, University of Basel, Basel, Switzerland.
Katayama S; Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm, Sweden.
Kere J; Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Molecular Neurology Research Program, University of Helsinki and Folkhälsan Institute of Genetics, Helsinki, Finland.
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Źródło:
Scientific reports [Sci Rep] 2016 Jul 14; Vol. 6, pp. 28995. Date of Electronic Publication: 2016 Jul 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Developmental*
Genes, Homeobox*
Blastocyst/*metabolism
Fetal Proteins/*genetics
Homeodomain Proteins/*genetics
Transcription Factors/*genetics
Amino Acid Motifs ; Amino Acid Sequence ; Cloning, Molecular ; Consensus Sequence ; DNA, Complementary/genetics ; Fetal Proteins/biosynthesis ; Gene Expression Profiling ; Gene Library ; Homeodomain Proteins/biosynthesis ; Human Embryonic Stem Cells/metabolism ; Humans ; Multigene Family ; Organ Specificity ; Pluripotent Stem Cells/metabolism ; Promoter Regions, Genetic ; Sequence Alignment ; Sequence Homology, Amino Acid ; Transcription Factors/biosynthesis
Czasopismo naukowe
Tytuł:
Ciona Brachyury proximal and distal enhancers have different FGF dose-response relationships.
Autorzy:
Harder MJ; Division of Biology, Kansas State University, Manhattan, Kansas, United States of America.
Hix J; Division of Biology, Kansas State University, Manhattan, Kansas, United States of America.
Reeves WM; Division of Biology, Kansas State University, Manhattan, Kansas, United States of America.
Veeman MT; Division of Biology, Kansas State University, Manhattan, Kansas, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2021 Jan 19; Vol. 17 (1), pp. e1009305. Date of Electronic Publication: 2021 Jan 19 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Ciona intestinalis/*genetics
Enhancer Elements, Genetic/*genetics
Fetal Proteins/*genetics
Fibroblast Growth Factors/*genetics
T-Box Domain Proteins/*genetics
Amino Acid Sequence/genetics ; Animals ; Ciona intestinalis/growth & development ; Gene Expression Regulation, Developmental/genetics ; MAP Kinase Signaling System/genetics ; Notochord/growth & development ; Notochord/metabolism ; Promoter Regions, Genetic/genetics ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł:
Impact of Brachyury on epithelial-mesenchymal transitions and chemosensitivity in non-small cell lung cancer.
Autorzy:
Xu K; Department of Thoracic Surgery, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning 110042, P.R. China.
Liu B; Department of Medical Oncology, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning 110042, P.R. China.
Liu Y; Department of Thoracic Surgery, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning 110042, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2015 Jul; Vol. 12 (1), pp. 995-1001. Date of Electronic Publication: 2015 Feb 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Carcinoma, Non-Small-Cell Lung/*genetics
Epithelial-Mesenchymal Transition/*genetics
Fetal Proteins/*genetics
Lung Neoplasms/*genetics
T-Box Domain Proteins/*genetics
Aged ; Aged, 80 and over ; Antigens, CD/genetics ; Antigens, CD/metabolism ; Antineoplastic Agents/pharmacology ; Cadherins/genetics ; Cadherins/metabolism ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Cell Survival/drug effects ; Cisplatin/pharmacology ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Female ; Fetal Proteins/antagonists & inhibitors ; Fetal Proteins/metabolism ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Staging ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction ; Survival Analysis ; T-Box Domain Proteins/antagonists & inhibitors ; T-Box Domain Proteins/metabolism
Czasopismo naukowe
Tytuł:
Isolation of a recombinant antibody specific for a surface marker of the corneal endothelium by phage display.
Autorzy:
Dorfmueller S; Experimental Therapeutics Centre, 31 Biopolis Way, Nanos level 3, Singapore, 138669 Singapore.
Tan HC; Experimental Therapeutics Centre, 31 Biopolis Way, Nanos level 3, Singapore, 138669 Singapore.
Ngoh ZX; Experimental Therapeutics Centre, 31 Biopolis Way, Nanos level 3, Singapore, 138669 Singapore.
Toh KY; Experimental Therapeutics Centre, 31 Biopolis Way, Nanos level 3, Singapore, 138669 Singapore.
Peh G; Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, Singapore.
Ang HP; Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, Singapore.
Seah XY; Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, Singapore.
Chin A; Bioprocessing Technology Institute, 20 Biopolis Way, Centros Level 4, Singapore, 138668 Singapore.
Choo A; Bioprocessing Technology Institute, 20 Biopolis Way, Centros Level 4, Singapore, 138668 Singapore.; Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore.
Mehta JS; Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, Singapore.
Sun W; Institute of Bioengineering and Nanotechnology, Synthetic Biosystems, 31 Biopolis Way, #04-01 Nanos, Singapore, 138669 Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
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Źródło:
Scientific reports [Sci Rep] 2016 Feb 23; Vol. 6, pp. 21661. Date of Electronic Publication: 2016 Feb 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Library*
Antibodies, Monoclonal/*isolation & purification
Antigens, CD/*metabolism
Cell Adhesion Molecules, Neuronal/*metabolism
Endothelial Cells/*metabolism
Endothelium, Corneal/*metabolism
Fetal Proteins/*metabolism
Single-Chain Antibodies/*isolation & purification
Antibodies, Monoclonal/genetics ; Antibodies, Monoclonal/metabolism ; Antibody Specificity ; Antigens, CD/genetics ; Biomarkers/metabolism ; Cell Adhesion Molecules, Neuronal/genetics ; Endothelial Cells/cytology ; Endothelium, Corneal/cytology ; Fetal Proteins/genetics ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Gene Expression ; Humans ; Immunoprecipitation ; Organ Specificity ; Primary Cell Culture ; Protein Binding ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Single-Chain Antibodies/genetics ; Single-Chain Antibodies/metabolism
Czasopismo naukowe
Tytuł:
Benign notochordal cell tumor of the lung: Report of a case.
Autorzy:
Shintaku M; Department of Pathology, Hikone Municipal Hospital, Shiga, Japan.
Kikuchi R; Department of Thoracic Surgery, Shiga General Hospital, Shiga, Japan.
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Źródło:
Pathology international [Pathol Int] 2020 Nov; Vol. 70 (11), pp. 871-875. Date of Electronic Publication: 2020 Aug 22.
Typ publikacji:
Case Reports
MeSH Terms:
Bone Neoplasms/*pathology
Lung/*pathology
Lung Neoplasms/*pathology
Neoplasms, Germ Cell and Embryonal/*pathology
Adult ; Bone Neoplasms/diagnosis ; Fetal Proteins/metabolism ; Humans ; Male ; Neoplasm Recurrence, Local/diagnosis ; Neoplasm Recurrence, Local/pathology ; Neoplasms, Germ Cell and Embryonal/diagnosis ; Soft Tissue Neoplasms/diagnosis ; Soft Tissue Neoplasms/pathology ; T-Box Domain Proteins/metabolism
Raport

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