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Wyszukujesz frazę ""Fisher, Andrew J."" wg kryterium: Autor


Tytuł :
Rational Design of RNA Editing Guide Strands: Cytidine Analogs at the Orphan Position.
Autorzy :
Doherty EE; Department of Chemistry, University of California, Davis, California 95616, United States.
Wilcox XE; Department of Chemistry, University of California, Davis, California 95616, United States.
van Sint Fiet L; ProQR Therapeutics, 2333 CK Leiden, The Netherlands.
Kemmel C; ProQR Therapeutics, 2333 CK Leiden, The Netherlands.
Turunen JJ; ProQR Therapeutics, 2333 CK Leiden, The Netherlands.
Klein B; ProQR Therapeutics, 2333 CK Leiden, The Netherlands.
Tantillo DJ; Department of Chemistry, University of California, Davis, California 95616, United States.
Fisher AJ; Department of Chemistry, University of California, Davis, California 95616, United States.; Department of Molecular and Cellular Biology, University of California, Davis, California 95616, United States.
Beal PA; Department of Chemistry, University of California, Davis, California 95616, United States.
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Źródło :
Journal of the American Chemical Society [J Am Chem Soc] 2021 May 12; Vol. 143 (18), pp. 6865-6876. Date of Electronic Publication: 2021 May 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Stepwise pathogenic evolution of Mycobacterium abscessus .
Autorzy :
Bryant JM; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; University of Cambridge Centre for AI in Medicine, Cambridge, UK.
Brown KP; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, UK.
Burbaud S; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.
Everall I; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; Wellcome Sanger Institute, Hinxton, UK.
Belardinelli JM; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Rodriguez-Rincon D; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.
Grogono DM; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, UK.
Peterson CM; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Verma D; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Evans IE; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, UK.
Ruis C; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; University of Cambridge Centre for AI in Medicine, Cambridge, UK.
Weimann A; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; University of Cambridge Centre for AI in Medicine, Cambridge, UK.
Arora D; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.
Malhotra S; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK.; Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.
Bannerman B; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; University of Cambridge Centre for AI in Medicine, Cambridge, UK.
Passemar C; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.
Templeton K; Queen Elizabeth University Hospital, NHS Greater Glasgow & Clyde, Glasgow, Scotland, UK.
MacGregor G; Queen Elizabeth University Hospital, NHS Greater Glasgow & Clyde, Glasgow, Scotland, UK.
Jiwa K; Newcastle University Translational and Clinical Research Institute and Institute of Transplantation, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Fisher AJ; Newcastle University Translational and Clinical Research Institute and Institute of Transplantation, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Blundell TL; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK.
Ordway DJ; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Jackson M; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Parkhill J; Wellcome Sanger Institute, Hinxton, UK. .; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Floto RA; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK. .; University of Cambridge Centre for AI in Medicine, Cambridge, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, UK.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Apr 30; Vol. 372 (6541).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Evolution, Molecular*
Genetic Fitness*
Communicable Diseases, Emerging/*microbiology
Lung/*microbiology
Mycobacterium Infections, Nontuberculous/*microbiology
Mycobacterium abscessus/*genetics
Mycobacterium abscessus/*pathogenicity
Pneumonia, Bacterial/*microbiology
Communicable Diseases, Emerging/transmission ; Datasets as Topic ; Epigenesis, Genetic ; Gene Transfer, Horizontal ; Genome, Bacterial ; Humans ; Mutation ; Mycobacterium Infections, Nontuberculous/transmission ; Pneumonia, Bacterial/transmission ; Virulence/genetics
Czasopismo naukowe
Tytuł :
The Crystal Structure of Calmodulin Bound to the Cardiac Ryanodine Receptor (RyR2) at Residues Phe4246-Val4271 Reveals a Fifth Calcium Binding Site.
Autorzy :
Yu Q; Department of Chemistry, University of California, Davis, California 95616, United States.
Anderson DE; Department of Chemistry, University of California, Davis, California 95616, United States.
Kaur R; Department of Chemistry, University of California, Davis, California 95616, United States.
Fisher AJ; Department of Chemistry, University of California, Davis, California 95616, United States.; Department of Molecular and Cellular Biology, University of California, Davis, California 95616, United States.
Ames JB; Department of Chemistry, University of California, Davis, California 95616, United States.
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Źródło :
Biochemistry [Biochemistry] 2021 Apr 13; Vol. 60 (14), pp. 1088-1096. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Crystal structure of breast regression protein 39 (BRP39), a signaling glycoprotein expressed during mammary gland apoptosis, at 2.6 Å resolution.
Autorzy :
Mohanty AK; Animal Biotechnology Centre, National Dairy Research Institute, Karnal 132001, Haryana, India. Electronic address: .
Choudhary S; Animal Biotechnology Centre, National Dairy Research Institute, Karnal 132001, Haryana, India.
Kaushik JK; Animal Biotechnology Centre, National Dairy Research Institute, Karnal 132001, Haryana, India.
Fisher AJ; Department of Chemistry, University of California Davis, Davis, CA 95616, United States; Department of Molecular and Cellular Biology, University of California Davis, Davis, CA 95616, United States.
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Źródło :
Journal of structural biology [J Struct Biol] 2021 Apr 08; Vol. 213 (2), pp. 107737. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Pro-IL-1β Is an Early Prognostic Indicator of Severe Donor Lung Injury During Ex Vivo Lung Perfusion.
Autorzy :
Major T; The Transplant Centre, University Hospital of South Manchester, Manchester, United Kingdom.; The Ex-Vivo Lab, The Division of Cell Matrix and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Ball AL; The Transplant Centre, University Hospital of South Manchester, Manchester, United Kingdom.; The Ex-Vivo Lab, The Division of Cell Matrix and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Stone JP; The Transplant Centre, University Hospital of South Manchester, Manchester, United Kingdom.; The Ex-Vivo Lab, The Division of Cell Matrix and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, Division of Inflammation, Immunity and Respiratory Medicine, University of Manchester, Manchester, United Kingdom.
Edge RJ; The Transplant Centre, University Hospital of South Manchester, Manchester, United Kingdom.; The Ex-Vivo Lab, The Division of Cell Matrix and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Lopez-Castejon G; Lydia Becker Institute of Immunology and Inflammation, Division of Inflammation, Immunity and Respiratory Medicine, University of Manchester, Manchester, United Kingdom.
Sjöberg T; Department of Cardiothoracic Surgery, Lund University and Skåne University Hospital, Lund, Sweden.
Andreasson A; Institute of Transplantation, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom.
Brough D; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.
Steen S; Department of Cardiothoracic Surgery, Lund University and Skåne University Hospital, Lund, Sweden.
Fisher AJ; Institute of Transplantation, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom.; Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, United Kingdom.
Fildes JE; The Transplant Centre, University Hospital of South Manchester, Manchester, United Kingdom.; The Ex-Vivo Lab, The Division of Cell Matrix and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation, Division of Inflammation, Immunity and Respiratory Medicine, University of Manchester, Manchester, United Kingdom.
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Źródło :
Transplantation [Transplantation] 2021 Apr 01; Vol. 105 (4), pp. 768-774.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Novel delivery of cellular therapy to reduce ischemia reperfusion injury in kidney transplantation.
Autorzy :
Thompson ER; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Bates L; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Ibrahim IK; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Sewpaul A; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Stenberg B; Department of Radiology, Freeman Hospital, Newcastle upon Tyne, UK.
McNeill A; Department of Radiology, Freeman Hospital, Newcastle upon Tyne, UK.
Figueiredo R; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Girdlestone T; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Wilkins GC; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Wang L; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Tingle SJ; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Scott WE 3rd; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
de Paula Lemos H; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Mellor AL; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Roobrouck VD; ReGenesys, Leuven, Belgium.
Ting AE; Athersys Inc., Cleveland, OH, USA.
Hosgood SA; NIHR Blood and Transplant Research Unit, Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Nicholson ML; NIHR Blood and Transplant Research Unit, Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Fisher AJ; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Ali S; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Sheerin NS; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Wilson CH; NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
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Źródło :
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2021 Apr; Vol. 21 (4), pp. 1402-1414. Date of Electronic Publication: 2020 Jun 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
The impact of the SARS-CoV-2 pandemic and COVID-19 on lung transplantation in the UK: Lessons learned from the first wave.
Autorzy :
Hardman G; Clinical Research and Clinical Audit Fellow in Cardiothoracic Transplantation, NHS Blood and Transplant, Bristol, UK.; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Sutcliffe R; Allied Health Professional representative, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.; Recipient Transplant Coordinator, Wythenshawe Hospital, Manchester, UK.
Hogg R; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Mumford L; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Grocott L; Heart and Lung transplant recipient coordinator, Queen Elizabeth Hospital, Birmingham, UK.
Mead-Regan SJ; Heart and Lung Transplant Recipient Coordinator, Great Ormond Street Hospital for Children, London, UK.
Nuttall J; Recipient Transplant Coordinator, Wythenshawe Hospital, Manchester, UK.
Dunn S; Heart and Lung transplant recipient coordinator, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Seeley P; Lead Nurse for Heart and Lung Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Clark S; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Quigley R; Lead Nurse for transplantation, Royal Papworth Hospital, Cambridge, UK.
Al-Attar N; Chair, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.
Booth K; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Dark JH; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Fisher AJ; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
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Corporate Authors :
NHS Blood, Transplant Cardiothoracic Advisory Group Clinical Audit Group
Źródło :
Clinical transplantation [Clin Transplant] 2021 Mar; Vol. 35 (3), pp. e14210. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Lung Transplantation*
Pandemics*
Registries*
Tissue Donors*
Waiting Lists*
COVID-19/*epidemiology
Transplant Recipients/*statistics & numerical data
Comorbidity ; Female ; Humans ; Lung Diseases/epidemiology ; Lung Diseases/surgery ; Male ; Retrospective Studies ; SARS-CoV-2 ; United Kingdom/epidemiology
Czasopismo naukowe
Tytuł :
Heart transplantation in the UK during the first wave of the SARS-CoV-2 pandemic.
Autorzy :
Hardman G; Clinical Research and Clinical Audit Fellow in Cardiothoracic Transplantation, NHS Blood and Transplant, Bristol, UK.; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Sutcliffe R; Allied Health Professional representative, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.
Hogg R; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Mumford L; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Grocott L; Heart and Lung transplant recipient coordinator, Queen Elizabeth Hospital, Birmingham, UK.
Jerrett L; Heart transplant recipient coordinator, Golden Jubilee Hospital, Glasgow, UK.
Mead-Regan SJ; Heart and Lung transplant recipient coordinator, Great Ormond Street Hospital for Children, London, UK.
Nuttall J; Recipient transplant coordinator, Wythenshawe hospital, Manchester, UK.
Dunn S; Heart and Lung transplant recipient coordinator, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Seeley P; Lead Nurse for Heart and Lung Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Quigley R; Lead Nurse for transplantation, Royal Papworth Hospital, Cambridge, UK.
Dalzell JR; Consultant cardiologist and clinical lead, Scottish National Advanced Heart Failure Service, Golden Jubilee National Hospital, Glasgow, UK.
Al-Attar N; Chair, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.
Parameshwar J; Chair Cardiothoracic Advisory Group, NHS Blood and Transplant, Bristol, UK.
Fisher AJ; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Booth K; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Dark JH; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
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Źródło :
Clinical transplantation [Clin Transplant] 2021 Feb 20, pp. e14261. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis.
Autorzy :
Guillotin D; Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK.
Taylor AR; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK.
Platé M; Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK.
Mercer PF; Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK.
Edwards LM; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK.
Haggart R; Epistem Ltd, Manchester, UK.
Miele G; Epistem Ltd, Manchester, UK.
McAnulty RJ; Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK.
Maher TM; National Heart and Lung Institute, Imperial College London, London, UK.
Hynds RE; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, UK.
Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, UK.
Marshall RP; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK.
Fisher AJ; Newcastle Fibrosis Research Group, Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.; Institute of Transplantation, Newcastle Upon Tyne Hospitals, Newcastle Upon Tyne, UK.
Blanchard AD; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK.
Chambers RC; Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK .
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Źródło :
Thorax [Thorax] 2021 Jan; Vol. 76 (1), pp. 73-82. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Idiopathic Pulmonary Fibrosis/*genetics
RNA/*genetics
Transcriptome/*genetics
Cells, Cultured ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Gene Expression Profiling ; Humans ; Idiopathic Pulmonary Fibrosis/metabolism ; Idiopathic Pulmonary Fibrosis/pathology ; Lung/metabolism ; Lung/pathology ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Tytuł :
Author Correction: c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis.
Autorzy :
Leslie J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. .
Macia MG; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Luli S; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Worrell JC; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Reilly WJ; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Paish HL; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Knox A; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Barksby BS; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Gee LM; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Zaki MYW; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Biochemistry Department, Faculty of Pharmacy, Minia University, Minia, Egypt.
Collins AL; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Burgoyne RA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Cameron R; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Bragg C; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Xu X; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Chung GW; Newcells Biotech, The Biosphere, Newcastle Helix, Newcastle upon Tyne, UK.
Brown CDA; Newcells Biotech, The Biosphere, Newcastle Helix, Newcastle upon Tyne, UK.
Blanchard AD; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK.
Nanthakumar CB; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK.
Karsdal M; Nordic Bioscience A/S, Biomarkers & Research, Herlev, Denmark.
Robinson SM; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Manas DM; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Sen G; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
French J; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
White SA; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Murphy S; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Trost M; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Zakrzewski JL; Center for Discovery and Innovation and John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ, USA.
Klein U; Division of Haematology & Immunology, Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK.
Schwabe RF; Department of Medicine, Columbia University, New York, NY, USA.
Mederacke I; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Nixon C; Cancer Research UK Beatson Institute, Garscube Estate, Glasgow, UK.
Bird T; Cancer Research UK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK.; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
Teuwen LA; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
Schoonjans L; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
Mann J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Fisher AJ; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Institute of Transplantation, The Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Sheerin NS; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Borthwick LA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Mann DA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. .; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK. .
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Źródło :
Nature metabolism [Nat Metab] 2021 Jan; Vol. 3 (1), pp. 118-119.
Typ publikacji :
Published Erratum
Tytuł :
The Journal of Heart and Lung Transplantation: A golden age draws to a close and a new dawn begins.
Autorzy :
Fisher AJ; Newcastle University Translational and Clinical Research Institute, The Medical School, Newcastle Upon Tyne, United Kingdom. Electronic address: a.j.fisher@newcastle.ac.uk.
Rogers JG; Duke Clinical Research Institute, Duke University Medical Centre, Durham, North Carolina.
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Źródło :
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2021 Jan; Vol. 40 (1), pp. 3. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Editorial
Opinia redakcyjna
Tytuł :
An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices.
Autorzy :
Khan MM; European Molecular Biology Laboratory, Heidelberg, Germany.; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany.; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
Poeckel D; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany.
Halavatyi A; European Molecular Biology Laboratory, Heidelberg, Germany.; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
Zukowska-Kasprzyk J; European Molecular Biology Laboratory, Heidelberg, Germany.
Stein F; European Molecular Biology Laboratory, Heidelberg, Germany.
Vappiani J; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany.
Sevin DC; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany.
Tischer C; European Molecular Biology Laboratory, Heidelberg, Germany.
Zinn N; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany.
Eley JD; Novel human genetics research unit, GSK, Stevenage, UK.
Gudmann NS; Nordic Bioscience, Herlev, Denmark.
Muley T; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Biobank Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany.
Winter H; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.; Biobank Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany.
Fisher AJ; Newcastle University Translational and Clinical Research Institute and Institute of Transplantation, Newcastle Upon Tyne Hospitals, Newcastle upon Tyne, UK.
Nanthakumar CB; Novel human genetics research unit, GSK, Stevenage, UK.
Bergamini G; Discovery Biology, Cellzome GmbH, GSK, Heidelberg, Germany.
Pepperkok R; European Molecular Biology Laboratory, Heidelberg, Germany .; Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
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Źródło :
The European respiratory journal [Eur Respir J] 2020 Dec 24. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.
Autorzy :
Unger EK; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Keller JP; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20174, USA.
Altermatt M; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Liang R; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Matsui A; Laboratory on Neurobiology of Compulsive Behaviors, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892, USA.
Dong C; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Hon OJ; Bowles Center for Alcohol Studies, Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Yao Z; Department of Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
Sun J; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Banala S; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20174, USA.
Flanigan ME; Bowles Center for Alcohol Studies, Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Jaffe DA; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Hartanto S; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Carlen J; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Mizuno GO; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Borden PM; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20174, USA.
Shivange AV; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Cameron LP; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Sinning S; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
Underhill SM; Laboratory of Molecular and Cellular Neurobiology, National Institute on Mental Health, NIH, Bethesda, MD 20892, USA.
Olson DE; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Amara SG; Laboratory of Molecular and Cellular Neurobiology, National Institute on Mental Health, NIH, Bethesda, MD 20892, USA.
Temple Lang D; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Rudnick G; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
Marvin JS; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20174, USA.
Lavis LD; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20174, USA.
Lester HA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Alvarez VA; Laboratory on Neurobiology of Compulsive Behaviors, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892, USA.
Fisher AJ; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Prescher JA; Department of Chemistry, University of California, Irvine, Irvine, CA 92697, USA.
Kash TL; Bowles Center for Alcohol Studies, Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Yarov-Yarovoy V; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA.
Gradinaru V; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Looger LL; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20174, USA. Electronic address: .
Tian L; Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA. Electronic address: .
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Źródło :
Cell [Cell] 2020 Dec 23; Vol. 183 (7), pp. 1986-2002.e26. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis.
Autorzy :
Worrell JC; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Leslie J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Smith GR; Bioinformatics Support Unit, Newcastle University, Newcastle upon Tyne, UK.
Zaki MYW; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.; Biochemistry Department, Faculty of Pharmacy, Minia University, Egypt.
Paish HL; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Knox A; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
James ML; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Cartwright TN; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
O'Reilly S; Department of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.
Kania G; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.
Distler O; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.
Distler JHW; Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
Herrick AL; Centre for Musculoskeletal Research, The University of Manchester, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester.
Jeziorska M; Division of Cardiovascular Sciences, University of Manchester, Manchester.
Borthwick LA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Fisher AJ; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.; Institute of Transplantation, The Freeman Hospital, High Heaton, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Mann J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Mann DA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Dec 01; Vol. 59 (12), pp. 3939-3951.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fibroblasts/*metabolism
Proto-Oncogene Proteins c-rel/*metabolism
Scleroderma, Systemic/*metabolism
Animals ; Extracellular Matrix/metabolism ; Fibrosis ; Fluorescent Antibody Technique ; Gene Expression Regulation ; Humans ; Lung/metabolism ; Lung/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Scleroderma, Systemic/pathology
Czasopismo naukowe
Tytuł :
A far-red cyanobacteriochrome lineage specific for verdins.
Autorzy :
Moreno MV; Department of Molecular and Cellular Biology, University of California, Davis, CA 95616.
Rockwell NC; Department of Molecular and Cellular Biology, University of California, Davis, CA 95616.
Mora M; Department of Molecular and Cellular Biology, University of California, Davis, CA 95616.
Fisher AJ; Department of Molecular and Cellular Biology, University of California, Davis, CA 95616.; Department of Chemistry, University of California, Davis, CA 95616.
Lagarias JC; Department of Molecular and Cellular Biology, University of California, Davis, CA 95616; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 10; Vol. 117 (45), pp. 27962-27970. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Phycobilins/*metabolism
Phytochrome/*genetics
Porphyrins/*genetics
Bacterial Proteins/metabolism ; Biliverdine/chemistry ; Cyanobacteria/genetics ; Cyanobacteria/metabolism ; Light ; Photoreceptor Cells/metabolism ; Photoreceptors, Microbial/chemistry ; Phycobilins/genetics ; Phycocyanin/genetics ; Phycocyanin/metabolism ; Phytochrome/metabolism ; Porphyrins/metabolism
Czasopismo naukowe
Tytuł :
Insight into the potential factors influencing the catalytic direction in cellobiose 2-epimerase by crystallization and mutagenesis.
Autorzy :
Feng Y; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Hua X; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Shen Q; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Matthews M; Department of Molecular and Cellular Biology, University of California Davis, Davis, CA 95616, USA.
Zhang Y; Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
Fisher AJ; Department of Molecular and Cellular Biology, University of California Davis, Davis, CA 95616, USA.
Lyu X; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Yang R; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
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Źródło :
Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2020 Nov 01; Vol. 76 (Pt 11), pp. 1104-1113. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis.
Autorzy :
Leslie J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. .
Macia MG; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Luli S; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Worrell JC; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Reilly WJ; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Paish HL; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Knox A; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Barksby BS; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Gee LM; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Zaki MYW; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Biochemistry Department, Faculty of Pharmacy, Minia University, Minia, Egypt.
Collins AL; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Burgoyne RA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Cameron R; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Bragg C; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Xu X; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Chung GW; Newcells Biotech, The Biosphere, Newcastle Helix, Newcastle upon Tyne, UK.
Brown CDA; Newcells Biotech, The Biosphere, Newcastle Helix, Newcastle upon Tyne, UK.
Blanchard AD; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK.
Nanthakumar CB; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK.
Karsdal M; Nordic Bioscience A/S, Biomarkers & Research, Herlev, Denmark.
Robinson SM; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Manas DM; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Sen G; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
French J; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
White SA; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Murphy S; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Trost M; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Zakrzewski JL; Center for Discovery and Innovation and John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ, USA.
Klein U; Division of Haematology & Immunology, Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK.
Schwabe RF; Department of Medicine, Columbia University, New York, NY, USA.
Mederacke I; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Nixon C; Cancer Research UK Beatson Institute, Garscube Estate, Glasgow, UK.
Bird T; Cancer Research UK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK.; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
Teuwen LA; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
Schoonjans L; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
Mann J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Fisher AJ; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Institute of Transplantation, The Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Sheerin NS; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Borthwick LA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Mann DA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. .; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK. .
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Źródło :
Nature metabolism [Nat Metab] 2020 Nov; Vol. 2 (11), pp. 1350-1367. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epithelium/*pathology
Liver Cirrhosis/*genetics
Liver Cirrhosis/*pathology
Macrophages/*pathology
Proto-Oncogene Proteins c-rel/*genetics
Animals ; Cell Polarity/genetics ; Gene Targeting ; Hepatocytes/pathology ; Hydroxyproline/metabolism ; Liver Cirrhosis/prevention & control ; Liver Regeneration/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitosis/genetics ; Paracrine Communication/genetics ; Phosphofructokinase-2/genetics ; Proto-Oncogene Proteins c-rel/antagonists & inhibitors ; Proto-Oncogene Proteins c-rel/metabolism
Czasopismo naukowe
Tytuł :
Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A.
Autorzy :
Hurlburt NK; Department of Chemistry, University of California, Davis, CA 95616, USA.
Guan J; Department of Chemistry, University of California, Davis, CA 95616, USA.
Ong H; Department of Chemistry, University of California, Davis, CA 95616, USA.
Yu H; Department of Chemistry, University of California, Davis, CA 95616, USA.
Chen X; Department of Chemistry, University of California, Davis, CA 95616, USA.
Fisher AJ; Department of Chemistry, University of California, Davis, CA 95616, USA.
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Źródło :
Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2020 Nov 01; Vol. 76 (Pt 11), pp. 557-567. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis.
Autorzy :
Gardner AI; Translational and Clinical Research Institute, Faculty of Medical Sciences, and.
Haq IJ; Translational and Clinical Research Institute, Faculty of Medical Sciences, and.; Paediatric Respiratory Medicine, Great North Children's Hospital, and.
Simpson AJ; Translational and Clinical Research Institute, Faculty of Medical Sciences, and.; Respiratory Medicine, Freeman Hospital, Newcastle upon Tyne Hospitals National Health Service Foundation Trust, Newcastle upon Tyne, United Kingdom.
Becker KA; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany.
Gallagher J; Translational and Clinical Research Institute, Faculty of Medical Sciences, and.
Saint-Criq V; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Verdon B; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Mavin E; Translational and Clinical Research Institute, Faculty of Medical Sciences, and.
Trigg A; Translational and Clinical Research Institute, Faculty of Medical Sciences, and.
Gray MA; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Koulman A; National Institute for Health Research Biomedical Research Centre Metabolomics and Lipidomics Facility, University of Cambridge, Cambridge, United Kingdom.
McDonnell MJ; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.; Department of Respiratory Medicine, Galway University Hospital, Galway, Ireland.
Fisher AJ; Translational and Clinical Research Institute, Faculty of Medical Sciences, and.
Kramer EL; Department of Pediatrics and.; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Clancy JP; Department of Pediatrics and.; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Ward C; Translational and Clinical Research Institute, Faculty of Medical Sciences, and.
Schuchman EH; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; and.
Gulbins E; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany.; Department of Surgery, University of Cincinnati, Cincinnati, Ohio.
Brodlie M; Translational and Clinical Research Institute, Faculty of Medical Sciences, and.; Paediatric Respiratory Medicine, Great North Children's Hospital, and.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2020 Oct 15; Vol. 202 (8), pp. 1133-1145.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acid Ceramidase/*metabolism
Acid Ceramidase/*pharmacology
Cystic Fibrosis/*drug therapy
Pneumonia/*diagnosis
Pseudomonas Infections/*diagnosis
Sphingolipids/*metabolism
Adolescent ; Alveolar Epithelial Cells/drug effects ; Animals ; Blotting, Western/methods ; Cells, Cultured ; Child ; Cystic Fibrosis/diagnosis ; Humans ; Inflammation/diagnosis ; Inflammation/drug therapy ; Mass Spectrometry/methods ; Mice ; Pneumonia/drug therapy ; Polymerase Chain Reaction/methods ; Pseudomonas Infections/drug therapy ; Sensitivity and Specificity ; Severity of Illness Index ; Young Adult
Czasopismo naukowe
Tytuł :
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis.
Autorzy :
John AE; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Graves RH; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Pun KT; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Vitulli G; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Forty EJ; Centre for Inflammation and Tissue Repair, University College London, London, UK.
Mercer PF; Centre for Inflammation and Tissue Repair, University College London, London, UK.
Morrell JL; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Barrett JW; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Rogers RF; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Hafeji M; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Bibby LI; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Gower E; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Morrison VS; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Man Y; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Roper JA; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Luckett JC; Radiological Sciences, University of Nottingham, Nottingham, UK.
Borthwick LA; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Barksby BS; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Burgoyne RA; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Barnes R; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Le J; Drug Design and Selection - Molecular Design, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Flint DJ; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
Pyne S; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
Habgood A; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Organ LA; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Joseph C; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Edwards-Pritchard RC; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Maher TM; NIHR Respiratory Clinical Research Facility, Royal Brompton Hospital, London, UK.; Fibrosis Research Group, National Heart and Lung Institute, Imperial College, London, UK.
Fisher AJ; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.; Institute of Transplantation, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS, Foundation Trust, Newcastle upon Tyne, UK.
Gudmann NS; Nordic Bioscience A/S, Biomarkers and Research, Herlev Hovedgade 205-207, Herlev, Denmark.
Leeming DJ; Nordic Bioscience A/S, Biomarkers and Research, Herlev Hovedgade 205-207, Herlev, Denmark.
Chambers RC; Centre for Inflammation and Tissue Repair, University College London, London, UK.
Lukey PT; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Marshall RP; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Macdonald SJF; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Jenkins RG; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK. .
Slack RJ; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
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Źródło :
Nature communications [Nat Commun] 2020 Sep 16; Vol. 11 (1), pp. 4659. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Butyrates/*pharmacology
Idiopathic Pulmonary Fibrosis/*drug therapy
Integrins/*antagonists & inhibitors
Naphthyridines/*pharmacology
Pyrazoles/*pharmacology
Pyrrolidines/*pharmacology
Administration, Inhalation ; Animals ; Antigens, Neoplasm/metabolism ; Bleomycin/toxicity ; Butyrates/administration & dosage ; Butyrates/metabolism ; Butyrates/pharmacokinetics ; Collagen/metabolism ; Disease Models, Animal ; Epithelial Cells/drug effects ; Humans ; Idiopathic Pulmonary Fibrosis/chemically induced ; Idiopathic Pulmonary Fibrosis/pathology ; Integrins/metabolism ; Male ; Mice, Inbred C57BL ; Molecular Docking Simulation ; Naphthyridines/administration & dosage ; Naphthyridines/metabolism ; Naphthyridines/pharmacokinetics ; Pyrazoles/administration & dosage ; Pyrazoles/metabolism ; Pyrazoles/pharmacokinetics ; Pyrrolidines/administration & dosage ; Pyrrolidines/metabolism ; Pyrrolidines/pharmacokinetics ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Tomography, Emission-Computed, Single-Photon ; Transforming Growth Factor beta/metabolism ; Translational Medical Research
Czasopismo naukowe

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