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Wyszukujesz frazę ""Fisher, Andrew J."" wg kryterium: Autor


Wyświetlanie 1-18 z 18
Tytuł:
Effector immune cells in chronic lung allograft dysfunction: A systematic review.
Autorzy:
Bos S; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.; Institute of Transplantation, The Newcastle Upon Tyne Hospital NHS Foundation Trust, Newcastle upon Tyne, UK.
Filby AJ; Flow Cytometry Core and Innovation, Methodology and Application Research Theme, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Vos R; Department of CHROMETA, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium.; Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.
Fisher AJ; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.; Institute of Transplantation, The Newcastle Upon Tyne Hospital NHS Foundation Trust, Newcastle upon Tyne, UK.
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Źródło:
Immunology [Immunology] 2022 May; Vol. 166 (1), pp. 17-37. Date of Electronic Publication: 2022 Mar 01.
Typ publikacji:
Journal Article; Review; Systematic Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Graft vs Host Disease*
Lung Transplantation*/adverse effects
Allografts ; Bronchoalveolar Lavage Fluid ; Chronic Disease ; Humans ; Lung ; Retrospective Studies ; Transplantation, Homologous
Czasopismo naukowe
Tytuł:
Transcriptional analysis identifies potential novel biomarkers associated with successful ex-vivo perfusion of human donor lungs.
Autorzy:
Ferdinand JR; Molecular Immunity Unit, University of Cambridge, Department of Medicine, Cambridge, UK.
Morrison MI; Institute of Transplantation, Freeman Hospital, Newcastle Upon Tyne, UK.
Andreasson A; Institute of Transplantation, Freeman Hospital, Newcastle Upon Tyne, UK.
Charlton C; Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK.
Chhatwal AK; Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK.
Scott WE 3rd; Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK.
Borthwick LA; Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK.
Clatworthy MR; Molecular Immunity Unit, University of Cambridge, Department of Medicine, Cambridge, UK.; Cellular Genetics, Wellcome Sanger Institute, Hinxton, UK.
Fisher AJ; Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK.; Institute of Transplantation, Freeman Hospital, Newcastle Upon Tyne, UK.
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Źródło:
Clinical transplantation [Clin Transplant] 2022 Apr; Vol. 36 (4), pp. e14570. Date of Electronic Publication: 2022 Jan 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung Transplantation*
Biomarkers/metabolism ; Humans ; Lung ; Perfusion ; Tissue Donors
Czasopismo naukowe
Tytuł:
Heart transplantation in the UK during the first wave of the SARS-CoV-2 pandemic.
Autorzy:
Hardman G; Clinical Research and Clinical Audit Fellow in Cardiothoracic Transplantation, NHS Blood and Transplant, Bristol, UK.; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Sutcliffe R; Allied Health Professional representative, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.
Hogg R; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Mumford L; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Grocott L; Heart and Lung transplant recipient coordinator, Queen Elizabeth Hospital, Birmingham, UK.
Jerrett L; Heart transplant recipient coordinator, Golden Jubilee Hospital, Glasgow, UK.
Mead-Regan SJ; Heart and Lung transplant recipient coordinator, Great Ormond Street Hospital for Children, London, UK.
Nuttall J; Recipient transplant coordinator, Wythenshawe hospital, Manchester, UK.
Dunn S; Heart and Lung transplant recipient coordinator, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Seeley P; Lead Nurse for Heart and Lung Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Quigley R; Lead Nurse for transplantation, Royal Papworth Hospital, Cambridge, UK.
Dalzell JR; Consultant cardiologist and clinical lead, Scottish National Advanced Heart Failure Service, Golden Jubilee National Hospital, Glasgow, UK.
Al-Attar N; Chair, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.
Parameshwar J; Chair Cardiothoracic Advisory Group, NHS Blood and Transplant, Bristol, UK.
Fisher AJ; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Booth K; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Dark JH; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
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Źródło:
Clinical transplantation [Clin Transplant] 2021 May; Vol. 35 (5), pp. e14261. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*
Heart Transplantation*
Humans ; Pandemics ; Retrospective Studies ; SARS-CoV-2 ; United Kingdom/epidemiology
Czasopismo naukowe
Tytuł:
Stepwise pathogenic evolution of Mycobacterium abscessus .
Autorzy:
Bryant JM; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; University of Cambridge Centre for AI in Medicine, Cambridge, UK.
Brown KP; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, UK.
Burbaud S; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.
Everall I; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; Wellcome Sanger Institute, Hinxton, UK.
Belardinelli JM; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Rodriguez-Rincon D; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.
Grogono DM; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, UK.
Peterson CM; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Verma D; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Evans IE; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, UK.
Ruis C; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; University of Cambridge Centre for AI in Medicine, Cambridge, UK.
Weimann A; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; University of Cambridge Centre for AI in Medicine, Cambridge, UK.
Arora D; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.
Malhotra S; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK.; Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.
Bannerman B; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.; University of Cambridge Centre for AI in Medicine, Cambridge, UK.
Passemar C; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK.
Templeton K; Queen Elizabeth University Hospital, NHS Greater Glasgow & Clyde, Glasgow, Scotland, UK.
MacGregor G; Queen Elizabeth University Hospital, NHS Greater Glasgow & Clyde, Glasgow, Scotland, UK.
Jiwa K; Newcastle University Translational and Clinical Research Institute and Institute of Transplantation, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Fisher AJ; Newcastle University Translational and Clinical Research Institute and Institute of Transplantation, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Blundell TL; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK.
Ordway DJ; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Jackson M; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO, USA.
Parkhill J; Wellcome Sanger Institute, Hinxton, UK. .; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Floto RA; Molecular Immunity Unit, University of Cambridge Department of Medicine, MRC Laboratory of Molecular Biology, Cambridge, UK. .; University of Cambridge Centre for AI in Medicine, Cambridge, UK.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, UK.
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Źródło:
Science (New York, N.Y.) [Science] 2021 Apr 30; Vol. 372 (6541).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Evolution, Molecular*
Genetic Fitness*
Communicable Diseases, Emerging/*microbiology
Lung/*microbiology
Mycobacterium Infections, Nontuberculous/*microbiology
Mycobacterium abscessus/*genetics
Mycobacterium abscessus/*pathogenicity
Pneumonia, Bacterial/*microbiology
Communicable Diseases, Emerging/transmission ; Datasets as Topic ; Epigenesis, Genetic ; Gene Transfer, Horizontal ; Genome, Bacterial ; Humans ; Mutation ; Mycobacterium Infections, Nontuberculous/transmission ; Pneumonia, Bacterial/transmission ; Virulence/genetics
Czasopismo naukowe
Tytuł:
The impact of the SARS-CoV-2 pandemic and COVID-19 on lung transplantation in the UK: Lessons learned from the first wave.
Autorzy:
Hardman G; Clinical Research and Clinical Audit Fellow in Cardiothoracic Transplantation, NHS Blood and Transplant, Bristol, UK.; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Sutcliffe R; Allied Health Professional representative, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.; Recipient Transplant Coordinator, Wythenshawe Hospital, Manchester, UK.
Hogg R; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Mumford L; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, UK.
Grocott L; Heart and Lung transplant recipient coordinator, Queen Elizabeth Hospital, Birmingham, UK.
Mead-Regan SJ; Heart and Lung Transplant Recipient Coordinator, Great Ormond Street Hospital for Children, London, UK.
Nuttall J; Recipient Transplant Coordinator, Wythenshawe Hospital, Manchester, UK.
Dunn S; Heart and Lung transplant recipient coordinator, Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Seeley P; Lead Nurse for Heart and Lung Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Clark S; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Quigley R; Lead Nurse for transplantation, Royal Papworth Hospital, Cambridge, UK.
Al-Attar N; Chair, Cardiothoracic Advisory Group Clinical Audit Group, NHS Blood and Transplant, Bristol, UK.
Booth K; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.
Dark JH; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Fisher AJ; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.; Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
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Corporate Authors:
NHS Blood, Transplant Cardiothoracic Advisory Group Clinical Audit Group
Źródło:
Clinical transplantation [Clin Transplant] 2021 Mar; Vol. 35 (3), pp. e14210. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji:
Journal Article; Multicenter Study
MeSH Terms:
Lung Transplantation*
Pandemics*
Registries*
Tissue Donors*
Waiting Lists*
COVID-19/*epidemiology
Transplant Recipients/*statistics & numerical data
Comorbidity ; Female ; Humans ; Lung Diseases/epidemiology ; Lung Diseases/surgery ; Male ; Retrospective Studies ; SARS-CoV-2 ; United Kingdom/epidemiology
Czasopismo naukowe
Tytuł:
Insight into the potential factors influencing the catalytic direction in cellobiose 2-epimerase by crystallization and mutagenesis.
Autorzy:
Feng Y; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Hua X; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Shen Q; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Matthews M; Department of Molecular and Cellular Biology, University of California Davis, Davis, CA 95616, USA.
Zhang Y; Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
Fisher AJ; Department of Molecular and Cellular Biology, University of California Davis, Davis, CA 95616, USA.
Lyu X; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Yang R; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
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Źródło:
Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2020 Nov 01; Vol. 76 (Pt 11), pp. 1104-1113. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Bacillus/*enzymology
Bacterial Proteins/*chemistry
Caldicellulosiruptor/*enzymology
Carbohydrate Epimerases/*chemistry
Spirochaeta/*enzymology
Bacterial Proteins/genetics ; Biocatalysis ; Carbohydrate Epimerases/genetics ; Catalytic Domain ; Isomerism ; Mutagenesis, Site-Directed ; Substrate Specificity
SCR Organism:
Bacillus thermoamylovorans; Caldicellulosiruptor saccharolyticus; Spirochaeta thermophila
Czasopismo naukowe
Tytuł:
Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A.
Autorzy:
Hurlburt NK; Department of Chemistry, University of California, Davis, CA 95616, USA.
Guan J; Department of Chemistry, University of California, Davis, CA 95616, USA.
Ong H; Department of Chemistry, University of California, Davis, CA 95616, USA.
Yu H; Department of Chemistry, University of California, Davis, CA 95616, USA.
Chen X; Department of Chemistry, University of California, Davis, CA 95616, USA.
Fisher AJ; Department of Chemistry, University of California, Davis, CA 95616, USA.
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Źródło:
Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2020 Nov 01; Vol. 76 (Pt 11), pp. 557-567. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji:
Journal Article
MeSH Terms:
Neisseria meningitidis, Serogroup A/*enzymology
Allosteric Site ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Carbohydrate Epimerases/chemistry ; Carbohydrate Epimerases/genetics ; Carbohydrate Epimerases/metabolism ; Catalytic Domain ; Crystallography, X-Ray ; Hydrolysis ; Models, Molecular ; Protein Conformation ; Sodium/chemistry ; Sodium/metabolism ; Uridine Diphosphate N-Acetylglucosamine/chemistry ; Uridine Diphosphate N-Acetylglucosamine/metabolism ; Uridine Diphosphate Sugars/chemistry ; Uridine Diphosphate Sugars/metabolism
Czasopismo naukowe
Tytuł:
Enhanced avidity from a multivalent fluorescent antimicrobial peptide enables pathogen detection in a human lung model.
Autorzy:
Akram AR; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom. .
Avlonitis N; EaStCHEM, The University of Edinburgh School of Chemistry, Joseph Black Building, West Mains Road, EH9 3FJ, Edinburgh, United Kingdom.
Scholefield E; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom.
Vendrell M; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom.
McDonald N; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom.
Aslam T; EaStCHEM, The University of Edinburgh School of Chemistry, Joseph Black Building, West Mains Road, EH9 3FJ, Edinburgh, United Kingdom.
Craven TH; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom.
Gray C; Clinical Research Imaging Centre, Queen's Medical Research Institute, Edinburgh BioQuarter, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom.
Collie DS; The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom.
Fisher AJ; Institute of Transplantation, Newcastle University, Freeman Hospital, High Heaton, Newcastle upon Tyne, NE7 7DN, United Kingdom.
Corris PA; Institute of Transplantation, Newcastle University, Freeman Hospital, High Heaton, Newcastle upon Tyne, NE7 7DN, United Kingdom.
Walsh T; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom.
Haslett C; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom.
Bradley M; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom. .; EaStCHEM, The University of Edinburgh School of Chemistry, Joseph Black Building, West Mains Road, EH9 3FJ, Edinburgh, United Kingdom. .
Dhaliwal K; EPSRC IRC PROTEUS Hub, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom. .
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Źródło:
Scientific reports [Sci Rep] 2019 Jun 10; Vol. 9 (1), pp. 8422. Date of Electronic Publication: 2019 Jun 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Biological*
Antimicrobial Cationic Peptides/*metabolism
Fluorescent Dyes/*metabolism
Lung/*microbiology
Animals ; Bacteria/metabolism ; Cells, Cultured ; Cystic Fibrosis/microbiology ; Disease Models, Animal ; Fungi/metabolism ; Humans ; Hydrophobic and Hydrophilic Interactions ; Inflammation/pathology ; Lung/pathology ; Oxadiazoles/metabolism ; Pneumonia/microbiology ; Sheep ; Signal-To-Noise Ratio
Czasopismo naukowe
Tytuł:
Structure of the Cladosporium fulvum Avr4 effector in complex with (GlcNAc)6 reveals the ligand-binding mechanism and uncouples its intrinsic function from recognition by the Cf-4 resistance protein.
Autorzy:
Hurlburt NK; Department of Chemistry, University of California, Davis, Davis, California, United States of America.
Chen LH; Department of Plant Pathology, University of California, Davis, Davis, California, United States of America.
Stergiopoulos I; Department of Plant Pathology, University of California, Davis, Davis, California, United States of America.
Fisher AJ; Department of Chemistry, University of California, Davis, Davis, California, United States of America.; Department of Molecular and Cellular Biology, University of California, Davis, Davis, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2018 Aug 27; Vol. 14 (8), pp. e1007263. Date of Electronic Publication: 2018 Aug 27 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Cladosporium*/genetics
Cladosporium*/immunology
Cladosporium*/metabolism
Cladosporium*/pathogenicity
Disease Resistance*
Acetylglucosamine/*metabolism
Fungal Proteins/*chemistry
Fungal Proteins/*metabolism
Solanum lycopersicum/*immunology
Membrane Glycoproteins/*metabolism
Plant Proteins/*metabolism
Acetylglucosamine/chemistry ; Fungal Proteins/physiology ; Ligands ; Solanum lycopersicum/genetics ; Solanum lycopersicum/microbiology ; Membrane Glycoproteins/chemistry ; Membrane Glycoproteins/genetics ; Models, Molecular ; Organisms, Genetically Modified ; Plant Diseases/immunology ; Plant Diseases/microbiology ; Plant Proteins/chemistry ; Plant Proteins/genetics ; Plants, Genetically Modified ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Structure, Quaternary ; Receptors, Cell Surface/chemistry ; Receptors, Cell Surface/metabolism
Czasopismo naukowe
Tytuł:
Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD.
Autorzy:
Clifford RL; Nottingham NIHR Biomedical Research Centre, Nottingham MRC Molecular Pathology Node, Division of Respiratory Medicine, University of Nottingham, Nottingham University Hospitals NHS Trust, City Hospital, Nottingham, UK.
Fishbane N; 2Centre for Heart Lung Innovation, University of British Columbia, Vancouver, Canada.
Patel J; Nottingham NIHR Biomedical Research Centre, Nottingham MRC Molecular Pathology Node, Division of Respiratory Medicine, University of Nottingham, Nottingham University Hospitals NHS Trust, City Hospital, Nottingham, UK.
MacIsaac JL; 3Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada.
McEwen LM; 3Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada.
Fisher AJ; 4Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
Brandsma CA; 5Department of Pathology and Medical Biology, University of Groningen, University Medical Center, Groningen, Groningen, The Netherlands.; 6GRIAC (Groningen Research Institute of Asthma and COPD), University of Groningen, University Medical Center, Groningen, The Netherlands.
Nair P; 7Firestone Institute for Respiratory Health, St Joseph's Healthcare and Department of Medicine, McMaster University, Hamilton, Ontario Canada.
Kobor MS; 3Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, Canada.
Hackett TL; 2Centre for Heart Lung Innovation, University of British Columbia, Vancouver, Canada.; 8Department of Anaesthesiology, Pharmacology, & Therapeutics, University of British Columbia, Vancouver, Canada.
Knox AJ; Nottingham NIHR Biomedical Research Centre, Nottingham MRC Molecular Pathology Node, Division of Respiratory Medicine, University of Nottingham, Nottingham University Hospitals NHS Trust, City Hospital, Nottingham, UK.
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Źródło:
Clinical epigenetics [Clin Epigenetics] 2018 Mar 05; Vol. 10, pp. 32. Date of Electronic Publication: 2018 Mar 05 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Methylation*
Up-Regulation*
Lung/*chemistry
Ornithine-Oxo-Acid Transaminase/*genetics
Parenchymal Tissue/*chemistry
Pulmonary Disease, Chronic Obstructive/*genetics
Receptors, Kainic Acid/*genetics
Aged ; Cells, Cultured ; CpG Islands ; Epigenesis, Genetic ; Female ; Fibroblasts/chemistry ; Gene Expression Profiling/methods ; Gene Expression Regulation ; Humans ; Lung/cytology ; Male ; Middle Aged ; Organ Specificity ; Parenchymal Tissue/cytology ; Sequence Analysis, DNA ; GluK2 Kainate Receptor
Czasopismo naukowe
Tytuł:
Arabidopsis receptor-like cytoplasmic kinase BIK1: purification, crystallization and X-ray diffraction analysis.
Autorzy:
Lal NK; Department of Plant Biology and The Genome Centre, College of Biological Sciences, University of California, Davis, CA 95616, USA.
Fisher AJ; Department of Chemistry and Department of Molecular, Cellular and Developmental Biology, University of California, Davis, CA 95616, USA.
Dinesh-Kumar SP; Department of Plant Biology and The Genome Centre, College of Biological Sciences, University of California, Davis, CA 95616, USA.
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Źródło:
Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2016 Oct 01; Vol. 72 (Pt 10), pp. 738-742. Date of Electronic Publication: 2016 Sep 22.
Typ publikacji:
Journal Article
MeSH Terms:
Arabidopsis/*chemistry
Arabidopsis Proteins/*chemistry
Protein Serine-Threonine Kinases/*chemistry
Amino Acid Sequence ; Arabidopsis/enzymology ; Arabidopsis/immunology ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/immunology ; Cloning, Molecular ; Crystallization ; Crystallography, X-Ray ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Expression ; Plasmids/chemistry ; Plasmids/metabolism ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/immunology ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/immunology ; X-Ray Diffraction
Czasopismo naukowe
Tytuł:
Tunable magnetoresistance in an asymmetrically coupled single-molecule junction.
Autorzy:
Warner B; 1] London Centre for Nanotechnology, University College London (UCL), London WC1H 0AH, UK [2] Department of Physics &Astronomy, UCL, London WC1E 6BT, UK.
El Hallak F; London Centre for Nanotechnology, University College London (UCL), London WC1H 0AH, UK.
Prüser H; London Centre for Nanotechnology, University College London (UCL), London WC1H 0AH, UK.
Sharp J; Surface Science Research Centre and Department of Chemistry, University of Liverpool, Liverpool L69 3BX, UK.
Persson M; 1] Surface Science Research Centre and Department of Chemistry, University of Liverpool, Liverpool L69 3BX, UK [2] Department of Applied Physics, Chalmers University of Technology, SE-412 96, Göteborg, Sweden.
Fisher AJ; 1] London Centre for Nanotechnology, University College London (UCL), London WC1H 0AH, UK [2] Department of Physics &Astronomy, UCL, London WC1E 6BT, UK.
Hirjibehedin CF; 1] London Centre for Nanotechnology, University College London (UCL), London WC1H 0AH, UK [2] Department of Physics &Astronomy, UCL, London WC1E 6BT, UK [3] Department of Chemistry, UCL, London WC1H 0AJ, UK.
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Źródło:
Nature nanotechnology [Nat Nanotechnol] 2015 Mar; Vol. 10 (3), pp. 259-63. Date of Electronic Publication: 2015 Jan 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł:
Potential for spin-based information processing in a thin-film molecular semiconductor.
Autorzy:
Warner M; 1] London Centre for Nanotechnology and Department of Physics and Astronomy, University College London, London WC1H 0AH, UK [2] Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA (M.W.); Department of Physics, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK (G.W.M.); RMD Inc., 44 Hunt Street, Watertown, Massachusetts 02472, USA (J.A.G.).
Din S
Tupitsyn IS
Morley GW
Stoneham AM
Gardener JA
Wu Z
Fisher AJ
Heutz S
Kay CW
Aeppli G
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Źródło:
Nature [Nature] 2013 Nov 28; Vol. 503 (7477), pp. 504-8. Date of Electronic Publication: 2013 Oct 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł:
Isolation and characterisation of human pulmonary microvascular endothelial cells from patients with severe emphysema.
Autorzy:
Mackay LS; Institute of Cellular Medicine, Newcastle University, Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK. />Dodd S
Dougall IG
Tomlinson W
Lordan J
Fisher AJ
Corris PA
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Źródło:
Respiratory research [Respir Res] 2013 Feb 20; Vol. 14, pp. 23. Date of Electronic Publication: 2013 Feb 20.
Typ publikacji:
Journal Article
MeSH Terms:
Severity of Illness Index*
Cell Separation/*methods
Endothelium, Vascular/*pathology
Flow Cytometry/*methods
Microvessels/*pathology
Pulmonary Emphysema/*pathology
Adult ; Aged ; Cells, Cultured ; Endothelium, Vascular/cytology ; Female ; Humans ; Lung/cytology ; Lung/pathology ; Male ; Microvessels/cytology ; Middle Aged
Czasopismo naukowe
Tytuł:
Targeted Antibiotic Prophylaxis for Lung Transplantation in Cystic Fibrosis Patients Colonised with Pseudomonas aeruginosa Using Multiple Combination Bactericidal Testing.
Autorzy:
Haja Mydin H; Institute of Transplantation, The Freeman Hospital, Newcastle upon Tyne NHS Hospitals Trust, High Heaton, Newcastle upon Tyne NE7 7DN, UK.
Corris PA
Nicholson A
Perry JD
Meachery G
Marrs EC
Peart S
Fagan C
Lordan JL
Fisher AJ
Gould FK
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Źródło:
Journal of transplantation [J Transplant] 2012; Vol. 2012, pp. 135738. Date of Electronic Publication: 2012 Jul 16.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Is CFTR-delF508 really absent from the apical membrane of the airway epithelium?
Autorzy:
Borthwick LA; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Botha P
Verdon B
Brodlie MJ
Gardner A
Bourn D
Johnson GE
Gray MA
Fisher AJ
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Źródło:
PloS one [PLoS One] 2011; Vol. 6 (8), pp. e23226. Date of Electronic Publication: 2011 Aug 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cystic Fibrosis/*metabolism
Cystic Fibrosis Transmembrane Conductance Regulator/*metabolism
Respiratory Mucosa/*metabolism
Bronchi/metabolism ; Cystic Fibrosis/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Fluorescent Antibody Technique ; Humans ; In Vitro Techniques ; Lung/metabolism ; Lung Transplantation ; Microscopy, Confocal
Czasopismo naukowe
Tytuł:
Primary bronchial epithelial cell culture from explanted cystic fibrosis lungs.
Autorzy:
Brodlie M; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom. m.j. />McKean MC
Johnson GE
Perry JD
Nicholson A
Verdon B
Gray MA
Dark JH
Pearson JP
Fisher AJ
Corris PA
Lordan J
Ward C
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Źródło:
Experimental lung research [Exp Lung Res] 2010 Mar; Vol. 36 (2), pp. 101-10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Culture Techniques*
Cystic Fibrosis/*pathology
Epithelial Cells/*cytology
Lung/*pathology
Adult ; Anti-Infective Agents ; Cells, Cultured ; Humans ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł:
Allosteric inhibition via R-state destabilization in ATP sulfurylase from Penicillium chrysogenum.
Autorzy:
MacRae IJ; Section of Molecular and Cellular Biology, University of California, One Shields Avenue, Davis, California 95616, USA.
Segel IH
Fisher AJ
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Źródło:
Nature structural biology [Nat Struct Biol] 2002 Dec; Vol. 9 (12), pp. 945-9.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Models, Molecular*
Penicillium chrysogenum/*enzymology
Sulfate Adenylyltransferase/*chemistry
Sulfate Adenylyltransferase/*metabolism
Allosteric Regulation ; Allosteric Site ; Binding Sites ; Crystallography, X-Ray ; Enzyme Stability ; Kinetics ; Motion ; Mutagenesis, Site-Directed ; Phosphoadenosine Phosphosulfate/chemistry ; Phosphoadenosine Phosphosulfate/metabolism ; Protein Structure, Tertiary ; Sulfate Adenylyltransferase/genetics
Czasopismo naukowe
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