Autor: "Fisher, Andrew J." - OpacWWW

Skocz do pozycji: 1 1.

Tytuł :: cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis.
Autorzy :: Worrell JC; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Leslie J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Smith GR; Bioinformatics Support Unit, Newcastle University, Newcastle upon Tyne, UK.
Zaki MYW; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.; Biochemistry Department, Faculty of Pharmacy, Minia University, Egypt.
Paish HL; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Knox A; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
James ML; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Cartwright TN; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
O'Reilly S; Department of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.
Kania G; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.
Distler O; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.
Distler JHW; Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
Herrick AL; Centre for Musculoskeletal Research, The University of Manchester, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester.
Jeziorska M; Division of Cardiovascular Sciences, University of Manchester, Manchester.
Borthwick LA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Fisher AJ; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.; Institute of Transplantation, The Freeman Hospital, High Heaton, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Mann J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Mann DA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.; Pokaż więcej
Źródło :: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Dec 01; Vol. 59 (12), pp. 3939-3951.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Fibroblasts/*metabolism
Proto-Oncogene Proteins c-rel/*metabolism
Scleroderma, Systemic/*metabolism
Animals ; Extracellular Matrix/metabolism ; Fibrosis ; Fluorescent Antibody Technique ; Gene Expression Regulation ; Humans ; Lung/metabolism ; Lung/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Scleroderma, Systemic/pathology
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Skocz do pozycji: 2 2.

Tytuł :: The circadian clock protein REVERBα inhibits pulmonary fibrosis development.
Autorzy :: Cunningham PS; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Meijer P; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Nazgiewicz A; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Anderson SG; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; The George Alleyne Chronic Disease Research Centre, The University of the West Indies, Bridgetown. Barbados BB11000.
Borthwick LA; Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Bagnall J; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Kitchen GB; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Lodyga M; Laboratory of Tissue Repair and Regeneration, Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Begley N; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Venkateswaran RV; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Shah R; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Mercer PF; Centre for Inflammation and Tissue Repair, Faculty of Medical Sciences, University College London, London WC1E 6JJ, United Kingdom.
Durrington HJ; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Henderson NC; Centre for Inflammation Research, University of Edinburgh, EH16 4TJ Edinburgh, United Kingdom.
Piper-Hanley K; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Fisher AJ; Institute of Transplantation, Freeman Hospital, The Newcastle upon Tyne Hospitals National Health Service Foundation Trust, Newcastle upon Tyne NE7 7DN, United Kingdom.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Chambers RC; Centre for Inflammation and Tissue Repair, Faculty of Medical Sciences, University College London, London WC1E 6JJ, United Kingdom.
Bechtold DA; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Gibbs JE; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Loudon AS; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Rutter MK; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Hinz B; Laboratory of Tissue Repair and Regeneration, Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Ray DW; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LE, United Kingdom.
Blaikley JF; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom; .; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.; Pokaż więcej
Źródło :: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 14; Vol. 117 (2), pp. 1139-1147. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: CLOCK Proteins/*antagonists & inhibitors
Circadian Clocks/*physiology
Fibroblasts/*drug effects
Pulmonary Fibrosis/*drug therapy
Animals ; Bleomycin/adverse effects ; CLOCK Proteins/genetics ; CLOCK Proteins/therapeutic use ; Gene Expression Regulation ; Gene Knockdown Techniques ; Humans ; Idiopathic Pulmonary Fibrosis ; Integrins ; Lung/pathology ; Male ; Mesenchymal Stem Cells ; Mice ; Mice, Knockout ; Myofibroblasts/drug effects ; Myofibroblasts/metabolism ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/pathology ; TATA Box Binding Protein-Like Proteins/metabolism ; Transcriptome
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Skocz do pozycji: 3 3.

Tytuł :: Cathepsin K in Lymphangioleiomyomatosis: LAM Cell-Fibroblast Interactions Enhance Protease Activity by Extracellular Acidification.
Autorzy :: Dongre A; Division of Respiratory Medicine and Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom. Electronic address: .
Clements D; Division of Respiratory Medicine and Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom.
Fisher AJ; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Johnson SR; Division of Respiratory Medicine and Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom.; Pokaż więcej
Źródło :: The American journal of pathology [Am J Pathol] 2017 Aug; Vol. 187 (8), pp. 1750-1762. Date of Electronic Publication: 2017 Jun 15.
Typ publikacji :: Journal Article
MeSH Terms :: Cathepsin K/*metabolism
Fibroblasts/*metabolism
Lung/*metabolism
Lung Neoplasms/*metabolism
Lymphangioleiomyomatosis/*metabolism
Peptide Hydrolases/*metabolism
Adult ; Cell Communication ; Cell Line ; Coculture Techniques ; Female ; Fibroblasts/pathology ; Humans ; Lung/pathology ; Lung Neoplasms/pathology ; Lymphangioleiomyomatosis/pathology
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Skocz do pozycji: 4 4.

Tytuł :: The Role of the Fibroblast in Inflammatory Upper Airway Conditions.
Autorzy :: Ball SL; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Otolaryngology Head and Neck Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom. Electronic address: .
Mann DA; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Wilson JA; Department of Otolaryngology Head and Neck Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
Fisher AJ; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.; Pokaż więcej
Źródło :: The American journal of pathology [Am J Pathol] 2016 Feb; Vol. 186 (2), pp. 225-33. Date of Electronic Publication: 2015 Dec 10.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :: Airway Remodeling/*immunology
Asthma/*immunology
Fibroblasts/*cytology
Inflammation/*immunology
Respiratory System/*immunology
Animals ; Cytokines/immunology ; Fibroblasts/immunology ; Humans
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: TNF-α/IL-17 synergy inhibits IL-13 bioactivity via IL-13Rα2 induction.
Autorzy :: Badalyan V; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md; Division of Gastroenterology, Hepatology, and Nutrition, Children's National Medical Center, Washington, DC.
Thompson R; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md.
Addo K; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md.
Borthwick LA; Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Fisher AJ; Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Ort T; Janssen R&D Companies of Johnson & Johnson, Springhouse, Pa.
Myers TG; Genomic Technologies Section, National Institute of Allergy and Infectious Disease, Bethesda, Md.
Wynn TA; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md.
Ramalingam TR; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md. Electronic address: .; Pokaż więcej
Źródło :: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2014 Oct; Vol. 134 (4), pp. 975-8.e5. Date of Electronic Publication: 2014 Jun 20.
Typ publikacji :: Letter; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Asthma/*immunology
Fibroblasts/*immunology
Interleukin-13/*immunology
Interleukin-13 Receptor alpha2 Subunit/*metabolism
Interleukin-17/*immunology
Lung/*pathology
Tumor Necrosis Factor-alpha/*immunology
Animals ; Asthma/therapy ; Cells, Cultured ; Humans ; Immunotherapy ; Interleukin-13 Receptor alpha2 Subunit/genetics ; Interleukin-4/immunology ; Mice ; Molecular Targeted Therapy ; Up-Regulation
: Raport

Szczegóły

Skocz do pozycji: 6 6.

Tytuł :: Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD
Autorzy :: Clifford, Rachel L.
Fishbane, Nick
Patel, Jamie
MacIsaac, Julia L.
McEwen, Lisa M.
Fisher, Andrew J.
Brandsma, Corry-AnkeAff5, Aff6
Nair, Parameswaran
Kobor, Michael S.
Hackett, Tillie-LouiseAff2, Aff8
Knox, Alan J.; Pokaż więcej
Źródło :: Clinical Epigenetics: The official journal of the Clinical Epigenetics Society. 10(1)
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Skocz do pozycji: 7 7.

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Skocz do pozycji: 8 8.

Tytuł :: Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis.
Autorzy :: Bartis, Domokos
Crowley, Louise E.
D'Souza, Vijay K.
Borthwick, Lee
Fisher, Andrew J.
Croft, Adam P.
Pongrácz, Judit E.
Thompson, Richard
Langman, Gerald
Buckley, Christopher D.
Thickett, David R.; Pokaż więcej
Temat :: MEMBRANE proteins
TRANSFORMING growth factors-beta
BIOMARKERS
IDIOPATHIC pulmonary fibrosis
RENAL fibrosis
IMMUNOHISTOCHEMISTRY
FIBROBLASTS
MYOFIBROBLASTS
ANTIGENS
BIOPSY
CELL culture
CELL physiology
CELLULAR signal transduction
COMPARATIVE studies
FLOW cytometry
GENES
LUNGS
RESEARCH methodology
MEDICAL cooperation
POLYMERASE chain reaction
RESEARCH
RESEARCH funding
RNA
TUMOR antigens
EVALUATION research
RETROSPECTIVE studies
SEVERITY of illness index
DIAGNOSIS
Źródło :: BMC Pulmonary Medicine; 4/14/2016, Vol. 16, p1-10, 10p, 1 Color Photograph, 2 Charts, 4 Graphs
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Skocz do pozycji: 9 9.

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Skocz do pozycji: 10 10.

Tytuł :: The reversal of pulmonary vascular remodeling through inhibition of p38 MAPK-alpha: a potential novel anti-inflammatory strategy in pulmonary hypertension.
Autorzy :: Church, Alistair C.
Martin, Damien H.
Wadsworth, Roger
Bryson, Gareth
Fisher, Andrew J.
Welsh, David J.
Peacock, Andrew J.; Pokaż więcej
Temat :: VASCULAR remodeling
MITOGEN-activated protein kinases
ANTI-inflammatory agents
PULMONARY hypertension treatment
FIBROBLASTS
Źródło :: American Journal of Physiology: Lung Cellular & Molecular Physiology; 8/15/2015, Vol. 309 Issue 4, pL333-L347, 15p
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