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Wyszukujesz frazę ""Fisher, Andrew J."" wg kryterium: Autor


Wyświetlanie 1-10 z 10
Tytuł :
cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis.
Autorzy :
Worrell JC; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Leslie J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Smith GR; Bioinformatics Support Unit, Newcastle University, Newcastle upon Tyne, UK.
Zaki MYW; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.; Biochemistry Department, Faculty of Pharmacy, Minia University, Egypt.
Paish HL; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Knox A; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
James ML; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Cartwright TN; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
O'Reilly S; Department of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.
Kania G; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.
Distler O; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.
Distler JHW; Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
Herrick AL; Centre for Musculoskeletal Research, The University of Manchester, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester.
Jeziorska M; Division of Cardiovascular Sciences, University of Manchester, Manchester.
Borthwick LA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Fisher AJ; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.; Institute of Transplantation, The Freeman Hospital, High Heaton, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Mann J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Mann DA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2020 Dec 01; Vol. 59 (12), pp. 3939-3951.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fibroblasts/*metabolism
Proto-Oncogene Proteins c-rel/*metabolism
Scleroderma, Systemic/*metabolism
Animals ; Extracellular Matrix/metabolism ; Fibrosis ; Fluorescent Antibody Technique ; Gene Expression Regulation ; Humans ; Lung/metabolism ; Lung/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Scleroderma, Systemic/pathology
Czasopismo naukowe
Tytuł :
The circadian clock protein REVERBα inhibits pulmonary fibrosis development.
Autorzy :
Cunningham PS; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Meijer P; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Nazgiewicz A; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Anderson SG; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; The George Alleyne Chronic Disease Research Centre, The University of the West Indies, Bridgetown. Barbados BB11000.
Borthwick LA; Fibrosis Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Bagnall J; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Kitchen GB; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Lodyga M; Laboratory of Tissue Repair and Regeneration, Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Begley N; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Venkateswaran RV; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Shah R; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Mercer PF; Centre for Inflammation and Tissue Repair, Faculty of Medical Sciences, University College London, London WC1E 6JJ, United Kingdom.
Durrington HJ; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Henderson NC; Centre for Inflammation Research, University of Edinburgh, EH16 4TJ Edinburgh, United Kingdom.
Piper-Hanley K; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Fisher AJ; Institute of Transplantation, Freeman Hospital, The Newcastle upon Tyne Hospitals National Health Service Foundation Trust, Newcastle upon Tyne NE7 7DN, United Kingdom.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Chambers RC; Centre for Inflammation and Tissue Repair, Faculty of Medical Sciences, University College London, London WC1E 6JJ, United Kingdom.
Bechtold DA; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Gibbs JE; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Loudon AS; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.
Rutter MK; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
Hinz B; Laboratory of Tissue Repair and Regeneration, Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Ray DW; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LE, United Kingdom.
Blaikley JF; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom; .; Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, United Kingdom.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 14; Vol. 117 (2), pp. 1139-1147. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CLOCK Proteins/*antagonists & inhibitors
Circadian Clocks/*physiology
Fibroblasts/*drug effects
Pulmonary Fibrosis/*drug therapy
Animals ; Bleomycin/adverse effects ; CLOCK Proteins/genetics ; CLOCK Proteins/therapeutic use ; Gene Expression Regulation ; Gene Knockdown Techniques ; Humans ; Idiopathic Pulmonary Fibrosis ; Integrins ; Lung/pathology ; Male ; Mesenchymal Stem Cells ; Mice ; Mice, Knockout ; Myofibroblasts/drug effects ; Myofibroblasts/metabolism ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/pathology ; TATA Box Binding Protein-Like Proteins/metabolism ; Transcriptome
Czasopismo naukowe
Tytuł :
Cathepsin K in Lymphangioleiomyomatosis: LAM Cell-Fibroblast Interactions Enhance Protease Activity by Extracellular Acidification.
Autorzy :
Dongre A; Division of Respiratory Medicine and Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom. Electronic address: .
Clements D; Division of Respiratory Medicine and Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom.
Fisher AJ; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Johnson SR; Division of Respiratory Medicine and Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom.
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Źródło :
The American journal of pathology [Am J Pathol] 2017 Aug; Vol. 187 (8), pp. 1750-1762. Date of Electronic Publication: 2017 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cathepsin K/*metabolism
Fibroblasts/*metabolism
Lung/*metabolism
Lung Neoplasms/*metabolism
Lymphangioleiomyomatosis/*metabolism
Peptide Hydrolases/*metabolism
Adult ; Cell Communication ; Cell Line ; Coculture Techniques ; Female ; Fibroblasts/pathology ; Humans ; Lung/pathology ; Lung Neoplasms/pathology ; Lymphangioleiomyomatosis/pathology
Czasopismo naukowe
Tytuł :
The Role of the Fibroblast in Inflammatory Upper Airway Conditions.
Autorzy :
Ball SL; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Otolaryngology Head and Neck Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom. Electronic address: .
Mann DA; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Wilson JA; Department of Otolaryngology Head and Neck Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
Fisher AJ; Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
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Źródło :
The American journal of pathology [Am J Pathol] 2016 Feb; Vol. 186 (2), pp. 225-33. Date of Electronic Publication: 2015 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Airway Remodeling/*immunology
Asthma/*immunology
Fibroblasts/*cytology
Inflammation/*immunology
Respiratory System/*immunology
Animals ; Cytokines/immunology ; Fibroblasts/immunology ; Humans
Czasopismo naukowe
Tytuł :
TNF-α/IL-17 synergy inhibits IL-13 bioactivity via IL-13Rα2 induction.
Autorzy :
Badalyan V; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md; Division of Gastroenterology, Hepatology, and Nutrition, Children's National Medical Center, Washington, DC.
Thompson R; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md.
Addo K; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md.
Borthwick LA; Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Fisher AJ; Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Ort T; Janssen R&D Companies of Johnson & Johnson, Springhouse, Pa.
Myers TG; Genomic Technologies Section, National Institute of Allergy and Infectious Disease, Bethesda, Md.
Wynn TA; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md.
Ramalingam TR; Immunopathogenesis Section, National Institute of Allergy and Infectious Disease, Bethesda, Md. Electronic address: .
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2014 Oct; Vol. 134 (4), pp. 975-8.e5. Date of Electronic Publication: 2014 Jun 20.
Typ publikacji :
Letter; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Asthma/*immunology
Fibroblasts/*immunology
Interleukin-13/*immunology
Interleukin-13 Receptor alpha2 Subunit/*metabolism
Interleukin-17/*immunology
Lung/*pathology
Tumor Necrosis Factor-alpha/*immunology
Animals ; Asthma/therapy ; Cells, Cultured ; Humans ; Immunotherapy ; Interleukin-13 Receptor alpha2 Subunit/genetics ; Interleukin-4/immunology ; Mice ; Molecular Targeted Therapy ; Up-Regulation
Raport
Tytuł :
Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD
Autorzy :
Clifford, Rachel L.
Fishbane, Nick
Patel, Jamie
MacIsaac, Julia L.
McEwen, Lisa M.
Fisher, Andrew J.
Brandsma, Corry-AnkeAff5, Aff6
Nair, Parameswaran
Kobor, Michael S.
Hackett, Tillie-LouiseAff2, Aff8
Knox, Alan J.
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Źródło :
Clinical Epigenetics: The official journal of the Clinical Epigenetics Society. 10(1)
Czasopismo naukowe
Tytuł :
The reversal of pulmonary vascular remodeling through inhibition of p38 MAPK-alpha: a potential novel anti-inflammatory strategy in pulmonary hypertension.
Autorzy :
Church, Alistair C.
Martin, Damien H.
Wadsworth, Roger
Bryson, Gareth
Fisher, Andrew J.
Welsh, David J.
Peacock, Andrew J.
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Temat :
VASCULAR remodeling
MITOGEN-activated protein kinases
ANTI-inflammatory agents
PULMONARY hypertension treatment
FIBROBLASTS
Źródło :
American Journal of Physiology: Lung Cellular & Molecular Physiology; 8/15/2015, Vol. 309 Issue 4, pL333-L347, 15p
Czasopismo naukowe
    Wyświetlanie 1-10 z 10

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