Autor: "Fitzgerald, David" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Targeting Receptors on Cancer Cells with Protein Toxins.
Autorzy:: Antignani A; Biotherapy Section, Laboratory of Molecular Biology, Center of Cancer Research, National Cancer Institute, NIH., 37 Convent Dr, Room 5124, Bethesda, MD 20892, USA.
Ho ECH; Biotherapy Section, Laboratory of Molecular Biology, Center of Cancer Research, National Cancer Institute, NIH., 37 Convent Dr, Room 5124, Bethesda, MD 20892, USA.
Bilotta MT; Biotherapy Section, Laboratory of Molecular Biology, Center of Cancer Research, National Cancer Institute, NIH., 37 Convent Dr, Room 5124, Bethesda, MD 20892, USA.
Qiu R; Biotherapy Section, Laboratory of Molecular Biology, Center of Cancer Research, National Cancer Institute, NIH., 37 Convent Dr, Room 5124, Bethesda, MD 20892, USA.
Sarnvosky R; Biotherapy Section, Laboratory of Molecular Biology, Center of Cancer Research, National Cancer Institute, NIH., 37 Convent Dr, Room 5124, Bethesda, MD 20892, USA.
FitzGerald DJ; Biotherapy Section, Laboratory of Molecular Biology, Center of Cancer Research, National Cancer Institute, NIH., 37 Convent Dr, Room 5124, Bethesda, MD 20892, USA.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2020 Sep 17; Vol. 10 (9). Date of Electronic Publication: 2020 Sep 17.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:: Antibodies, Monoclonal/*immunology
Immunotoxins/*immunology
Neoplasms/*immunology
Receptors, Cell Surface/*immunology
Toxins, Biological/*immunology
Animals ; Antibodies, Monoclonal/metabolism ; Cell Survival/drug effects ; Cell Survival/immunology ; Humans ; Immunotoxins/metabolism ; Immunotoxins/therapeutic use ; Ligands ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Protein Binding ; Receptors, Cell Surface/antagonists & inhibitors ; Receptors, Cell Surface/metabolism ; Toxins, Biological/metabolism

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Skocz do pozycji: 2.

Tytuł:: Immunotoxin Therapies for the Treatment of Epidermal Growth Factor Receptor-Dependent Cancers.
Autorzy:: Simon N; Biotherapy Section, Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, 37/5124 Bethesda, MD 20892, USA. .
FitzGerald D; Biotherapy Section, Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, 37/5124 Bethesda, MD 20892, USA. .; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2016 May 04; Vol. 8 (5). Date of Electronic Publication: 2016 May 04.
Typ publikacji:: Journal Article; Review
MeSH Terms:: ErbB Receptors/*immunology
Immunotoxins/*therapeutic use
Neoplasms/*therapy
Animals ; Humans ; Immunotherapy ; Neoplasms/immunology

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Skocz do pozycji: 3.

Tytuł:: Immunotoxins: the role of the toxin.
Autorzy:: Antignani A; Biotherapy Section, Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, 37 Convent Dr, Bethesda, MD 20892, USA. />Fitzgerald D; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2013 Aug 21; Vol. 5 (8), pp. 1486-502. Date of Electronic Publication: 2013 Aug 21.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms:: Immunotoxins/*therapeutic use
Animals ; Antibodies, Monoclonal/therapeutic use ; Bacterial Toxins/therapeutic use ; Drug Therapy, Combination ; Humans ; Neoplasms/therapy ; Recombinant Fusion Proteins/therapeutic use

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Skocz do pozycji: 4.

Tytuł:: Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary.
Autorzy:: Tortorella LL; Department of Biochemistry, Weill Cornell Medical College, New York, New York, United States of America.
Pipalia NH
Mukherjee S
Pastan I
Fitzgerald D
Maxfield FR; Pokaż więcej
Źródło:: PloS one [PLoS One] 2012; Vol. 7 (10), pp. e47320. Date of Electronic Publication: 2012 Oct 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Furin/*metabolism
Immunotoxins/*metabolism
Membrane Glycoproteins/*metabolism
Animals ; Antibodies, Monoclonal/metabolism ; CHO Cells ; Cell Survival/genetics ; Cell Survival/physiology ; Cricetinae ; Exotoxins/metabolism ; Fluorescent Antibody Technique, Indirect ; Furin/genetics ; Humans ; Immunoblotting ; Immunotoxins/genetics ; Membrane Glycoproteins/genetics ; Receptors, Transferrin/genetics ; Receptors, Transferrin/metabolism

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Skocz do pozycji: 5.

Tytuł:: Recombinant immunotoxins and other therapies for relapsed/refractory hairy cell leukemia.
Autorzy:: Kreitman RJ; Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. />Arons E
Stetler-Stevenson M
Fitzgerald DJ
Wilson WH
Pastan I; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2011 Jun; Vol. 52 Suppl 2, pp. 82-6.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Immunotoxins/*therapeutic use
Leukemia, Hairy Cell/*drug therapy
Clinical Trials as Topic ; Humans ; Salvage Therapy/methods

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Skocz do pozycji: 6.

Tytuł:: Immunotoxins with decreased immunogenicity and improved activity.
Autorzy:: Pastan I; Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Onda M
Weldon J
Fitzgerald D
Kreitman R; Pokaż więcej
Źródło:: Leukemia & lymphoma [Leuk Lymphoma] 2011 Jun; Vol. 52 Suppl 2, pp. 87-90. Date of Electronic Publication: 2011 Apr 19.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Epitopes, B-Lymphocyte/*genetics
Immunotoxins/*therapeutic use
Leukemia, Lymphocytic, Chronic, B-Cell/*drug therapy
Animals ; Humans ; Immunotoxins/immunology ; Immunotoxins/pharmacology ; Leukemia, Lymphocytic, Chronic, B-Cell/immunology ; Mice ; Mutation

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Skocz do pozycji: 7.

Tytuł:: The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy.
Autorzy:: Xiang X; Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Phung Y
Feng M
Nagashima K
Zhang J
Broaddus VC
Hassan R
Fitzgerald D
Ho M; Pokaż więcej
Źródło:: PloS one [PLoS One] 2011 Jan 31; Vol. 6 (1), pp. e14640. Date of Electronic Publication: 2011 Jan 31.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:: Antibodies, Monoclonal/*therapeutic use
Immunotoxins/*therapeutic use
Mesothelioma/*pathology
Spheroids, Cellular/*pathology
Tumor Microenvironment/*immunology
Antibodies/therapeutic use ; Cadherins/analysis ; Cadherins/immunology ; Cell Culture Techniques/methods ; Humans ; Kinetics ; Mesothelioma/drug therapy ; Microscopy, Electron ; Tumor Cells, Cultured

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Skocz do pozycji: 8.

Tytuł:: Immunotoxin therapy of cancer.
Autorzy:: Pastan I; Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institues of Health, 37 Convent Drive, Bethesda, MD 20892-4264, USA. />Hassan R
Fitzgerald DJ
Kreitman RJ; Pokaż więcej
Źródło:: Nature reviews. Cancer [Nat Rev Cancer] 2006 Jul; Vol. 6 (7), pp. 559-65.
Typ publikacji:: Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Immunotherapy*
Antineoplastic Agents/*therapeutic use
Immunotoxins/*therapeutic use
Neoplasms/*therapy
Animals ; Bacterial Toxins/immunology ; Bacterial Toxins/therapeutic use ; Humans ; Immunoglobulin Variable Region/immunology ; Immunoglobulin Variable Region/therapeutic use ; Recombinant Proteins/immunology ; Recombinant Proteins/therapeutic use

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