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    Wyświetlanie 1-9 z 9
    Tytuł:
    Correlative light-electron microscopy methods to characterize the ultrastructural features of the replicative and dormant liver stages of Plasmodium parasites.
    Autorzy:
    Mitchell G; Open Innovation at Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA. .
    Torres L; Open Innovation at Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA.
    Fishbaugher ME; Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA.
    Lam M; Open Innovation at Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA.
    Chuenchob V; Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA.
    Zalpuri R; Electron Microscope Laboratory, University of California, Berkeley, CA, USA.
    Ramasubban S; Electron Microscope Laboratory, University of California, Berkeley, CA, USA.
    Baxter CN; Electron Microscope Laboratory, University of California, Berkeley, CA, USA.
    Flannery EL; Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA.
    Harupa A; Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA.
    Mikolajczak SA; Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA.
    Jorgens DM; Electron Microscope Laboratory, University of California, Berkeley, CA, USA.
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    Źródło:
    Malaria journal [Malar J] 2024 Feb 21; Vol. 23 (1), pp. 53. Date of Electronic Publication: 2024 Feb 21.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Parasites*
    Malaria*/parasitology
    Animals ; Humans ; Liver/parasitology ; Plasmodium berghei ; Microscopy, Electron
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi.
    Autorzy:
    Mitchell G; Open Innovation at Novartis Institute for Tropical Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA, USA. .
    Roma G; Chemical Biology & Therapeutics, Novartis Institutes for BioMedical Research, Basel, Switzerland.
    Voorberg-van der Wel A; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
    Beibel M; Chemical Biology & Therapeutics, Novartis Institutes for BioMedical Research, Basel, Switzerland.
    Zeeman AM; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
    Schuierer S; Chemical Biology & Therapeutics, Novartis Institutes for BioMedical Research, Basel, Switzerland.
    Torres L; Open Innovation at Novartis Institute for Tropical Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
    Flannery EL; Novartis Institute for Tropical Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
    Kocken CHM; Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
    Mikolajczak SA; Novartis Institute for Tropical Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
    Diagana TT; Novartis Institute for Tropical Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA, USA.
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    Źródło:
    Malaria journal [Malar J] 2022 Dec 23; Vol. 21 (1), pp. 393. Date of Electronic Publication: 2022 Dec 23.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Plasmodium cynomolgi*/genetics
    Parasites*
    Malaria*/parasitology
    Animals ; Macaca mulatta/parasitology ; Hepatocytes/parasitology ; Liver/parasitology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Validation of the protein kinase Pf CLK3 as a multistage cross-species malarial drug target.
    Autorzy:
    Alam MM; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8QQ, UK.
    Sanchez-Azqueta A; Centre for Translational Pharmacology, Institute of Molecular Cell and Systems Biology, University of Glasgow, Glasgow G12 8QQ, UK.
    Janha O; Centre for Translational Pharmacology, Institute of Molecular Cell and Systems Biology, University of Glasgow, Glasgow G12 8QQ, UK.
    Flannery EL; Novartis Institute for Biomedical Research, Emeryville, CA 94608, USA.
    Mahindra A; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
    Mapesa K; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
    Char AB; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Science, University of Glasgow, Glasgow G12 8QQ, UK.
    Sriranganadane D; Structural Genomics Consortium, Universidade Estadual de Campinas, Campinas, São Paulo 13083-886, Brazil.
    Brancucci NMB; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.
    Antonova-Koch Y; Skaggs School of Pharmaceutical Sciences, UC Health Sciences Center for Immunology, Infection and Inflammation, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA.
    Crouch K; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8QQ, UK.
    Simwela NV; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8QQ, UK.
    Millar SB; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8QQ, UK.
    Akinwale J; Medical Research Council Toxicology Unit, University of Leicester, Leicester LE1 9HN, UK.
    Mitcheson D; Department of Molecular Cell Biology, University of Leicester, Leicester LE1 9HN, UK.
    Solyakov L; Medical Research Council Toxicology Unit, University of Leicester, Leicester LE1 9HN, UK.
    Dudek K; Medical Research Council Toxicology Unit, University of Leicester, Leicester LE1 9HN, UK.
    Jones C; Medical Research Council Toxicology Unit, University of Leicester, Leicester LE1 9HN, UK.
    Zapatero C; Diseases of the Developing World, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain.
    Doerig C; Biomedical Science Cluster, School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology, Melbourne, VIC 3000, Australia.
    Nwakanma DC; MRC Unit the Gambia, Fajara, Banjul, The Gambia.
    Vázquez MJ; Diseases of the Developing World, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain.
    Colmenarejo G; Biostatistics and Bioinformatics Unit, IMDEA Food Institute, 28049 Madrid, Spain.
    Lafuente-Monasterio MJ; Diseases of the Developing World, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain.
    Leon ML; Diseases of the Developing World, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain.
    Godoi PHC; Structural Genomics Consortium, Universidade Estadual de Campinas, Campinas, São Paulo 13083-886, Brazil.
    Elkins JM; Structural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7DQ, UK.
    Waters AP; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8QQ, UK.
    Jamieson AG; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
    Álvaro EF; Diseases of the Developing World, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain.
    Ranford-Cartwright LC; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Science, University of Glasgow, Glasgow G12 8QQ, UK.
    Marti M; Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow G12 8QQ, UK.
    Winzeler EA; Skaggs School of Pharmaceutical Sciences, UC Health Sciences Center for Immunology, Infection and Inflammation, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA.
    Gamo FJ; Diseases of the Developing World, GlaxoSmithKline, 28760 Tres Cantos, Madrid, Spain.
    Tobin AB; Centre for Translational Pharmacology, Institute of Molecular Cell and Systems Biology, University of Glasgow, Glasgow G12 8QQ, UK. .
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    Źródło:
    Science (New York, N.Y.) [Science] 2019 Aug 30; Vol. 365 (6456).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Molecular Targeted Therapy*
    Antimalarials/*pharmacology
    Plasmodium falciparum/*drug effects
    Protein Kinase Inhibitors/*pharmacology
    Protein Serine-Threonine Kinases/*antagonists & inhibitors
    Protein-Tyrosine Kinases/*antagonists & inhibitors
    Protozoan Proteins/*antagonists & inhibitors
    Animals ; Antimalarials/chemistry ; Antimalarials/isolation & purification ; Antimalarials/therapeutic use ; Gametogenesis/drug effects ; High-Throughput Screening Assays ; Mice ; Mice, Inbred BALB C ; Plasmodium falciparum/enzymology ; Plasmodium falciparum/genetics ; Protein Kinase Inhibitors/isolation & purification ; Protein Kinase Inhibitors/therapeutic use ; Protein Serine-Threonine Kinases/genetics ; Protein-Tyrosine Kinases/genetics ; Protozoan Proteins/genetics ; RNA Splicing/genetics ; Small Molecule Libraries/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages.
    Autorzy:
    Schafer C; Center for Infectious Disease Research, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA.
    Dambrauskas N; Center for Infectious Disease Research, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA.
    Steel RW; Center for Infectious Disease Research, Seattle, WA, USA.; The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
    Carbonetti S; Center for Infectious Disease Research, Seattle, WA, USA.
    Chuenchob V; Center for Infectious Disease Research, Seattle, WA, USA.
    Flannery EL; Center for Infectious Disease Research, Seattle, WA, USA.; Novartis Institute for Tropical Diseases, Emeryville, CA, USA.
    Vigdorovich V; Center for Infectious Disease Research, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA.
    Oliver BG; Center for Infectious Disease Research, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA.
    Roobsoong W; Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
    Maher SP; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA.
    Kyle D; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA.
    Sattabongkot J; Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
    Kappe SHI; Center for Infectious Disease Research, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA.; Department of Global Health, University of Washington, Seattle, USA.
    Mikolajczak SA; Center for Infectious Disease Research, Seattle, WA, USA. .; Novartis Institute for Tropical Diseases, Emeryville, CA, USA. .
    Sather DN; Center for Infectious Disease Research, Seattle, WA, USA. .; Seattle Children's Research Institute, Seattle, WA, USA. .; Department of Global Health, University of Washington, Seattle, USA. .
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    Źródło:
    Malaria journal [Malar J] 2018 Oct 17; Vol. 17 (1), pp. 370. Date of Electronic Publication: 2018 Oct 17.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Antibodies, Protozoan/*physiology
    Liver/*parasitology
    Plasmodium vivax/*isolation & purification
    Sporozoites/*immunology
    Biomarkers/analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    PfCap380 as a marker for Plasmodium falciparum oocyst development in vivo and in vitro.
    Autorzy:
    Itsara LS; MalarVx, Inc., 307 Westlake Ave N Suite 200, Seattle, WA, 98109, USA.
    Zhou Y; MalarVx, Inc., 307 Westlake Ave N Suite 200, Seattle, WA, 98109, USA.
    Do J; MalarVx, Inc., 307 Westlake Ave N Suite 200, Seattle, WA, 98109, USA.
    Dungel S; MalarVx, Inc., 307 Westlake Ave N Suite 200, Seattle, WA, 98109, USA.
    Fishbaugher ME; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA, 98109, USA.
    Betz WW; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA, 98109, USA.
    Nguyen T; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA, 98109, USA.
    Navarro MJ; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA, 98109, USA.
    Flannery EL; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA, 98109, USA.
    Vaughan AM; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA, 98109, USA.
    Kappe SHI; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA, 98109, USA.
    Ghosh AK; MalarVx, Inc., 307 Westlake Ave N Suite 200, Seattle, WA, 98109, USA. .; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA, 98109, USA. .
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    Źródło:
    Malaria journal [Malar J] 2018 Apr 02; Vol. 17 (1), pp. 135. Date of Electronic Publication: 2018 Apr 02.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    DNA, Protozoan/*genetics
    Genetic Markers/*genetics
    Malaria, Falciparum/*parasitology
    Oocysts/*genetics
    Plasmodium falciparum/*genetics
    Humans ; Limit of Detection ; Malaria, Falciparum/diagnosis ; Molecular Typing ; Parasitology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.
    Autorzy:
    Cowell AN; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Istvan ES; Departments of Medicine and Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Lukens AK; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.; Infectious Disease Program, The Broad Institute, 415 Main Street, Cambridge, MA 02142, USA.
    Gomez-Lorenzo MG; Tres Cantos Medicines Development Campus, Malaria Discovery Performance Unit, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
    Vanaerschot M; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
    Sakata-Kato T; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.
    Flannery EL; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Magistrado P; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.
    Owen E; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
    Abraham M; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    LaMonte G; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Painter HJ; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
    Williams RM; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Franco V; Tres Cantos Medicines Development Campus, Malaria Discovery Performance Unit, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
    Linares M; Tres Cantos Medicines Development Campus, Malaria Discovery Performance Unit, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
    Arriaga I; Tres Cantos Medicines Development Campus, Malaria Discovery Performance Unit, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
    Bopp S; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.
    Corey VC; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Gnädig NF; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
    Coburn-Flynn O; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
    Reimer C; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Gupta P; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Murithi JM; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
    Moura PA; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
    Fuchs O; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Sasaki E; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Kim SW; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Teng CH; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Wang LT; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Akidil A; Malaria Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
    Adjalley S; Malaria Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
    Willis PA; Medicines for Malaria Venture, Post Office Box 1826, 20 Route de Pre-Bois, 1215 Geneva 15, Switzerland.
    Siegel D; Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD, 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Tanaseichuk O; Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
    Zhong Y; Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
    Zhou Y; Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
    Llinás M; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
    Ottilie S; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA.
    Gamo FJ; Tres Cantos Medicines Development Campus, Malaria Discovery Performance Unit, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
    Lee MCS; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.; Malaria Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
    Goldberg DE; Departments of Medicine and Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
    Fidock DA; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.; Division of Infectious Diseases, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
    Wirth DF; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.; Infectious Disease Program, The Broad Institute, 415 Main Street, Cambridge, MA 02142, USA.
    Winzeler EA; School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, CA 92093, USA. .; Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD, 9500 Gilman Drive, La Jolla, CA 92093, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2018 Jan 12; Vol. 359 (6372), pp. 191-199.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genome, Protozoan*
    Antimalarials/*pharmacology
    Drug Resistance/*genetics
    Plasmodium falciparum/*drug effects
    Plasmodium falciparum/*genetics
    Activation, Metabolic ; Alleles ; DNA Copy Number Variations ; Directed Molecular Evolution ; Drug Resistance, Multiple/genetics ; Genes, Protozoan ; Metabolomics ; Mutation ; Plasmodium falciparum/growth & development ; Selection, Genetic ; Transcription Factors/chemistry ; Transcription Factors/genetics ; Transcription Factors/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Proteogenomic analysis of the total and surface-exposed proteomes of Plasmodium vivax salivary gland sporozoites.
    Autorzy:
    Swearingen KE; Institute for Systems Biology, Seattle, Washington, United States of America.; Center for Infectious Disease Research, Seattle, Washington, United States of America.
    Lindner SE; Center for Infectious Disease Research, Seattle, Washington, United States of America.; Department of Biochemistry and Molecular Biology, Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America.
    Flannery EL; Center for Infectious Disease Research, Seattle, Washington, United States of America.
    Vaughan AM; Center for Infectious Disease Research, Seattle, Washington, United States of America.
    Morrison RD; Center for Infectious Disease Research, Seattle, Washington, United States of America.
    Patrapuvich R; Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
    Koepfli C; Population Health and Immunity Division, The Walter and Eliza Hall Institute for Medical Research, Parkville, Victoria, Australia.
    Muller I; Population Health and Immunity Division, The Walter and Eliza Hall Institute for Medical Research, Parkville, Victoria, Australia.; Malaria: Parasites & Hosts Unit, Institut Pasteur, Paris, France.
    Jex A; Population Health and Immunity Division, The Walter and Eliza Hall Institute for Medical Research, Parkville, Victoria, Australia.; Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.
    Moritz RL; Institute for Systems Biology, Seattle, Washington, United States of America.
    Kappe SHI; Center for Infectious Disease Research, Seattle, Washington, United States of America.; Department of Global Health, University of Washington, Seattle, Washington, United States of America.
    Sattabongkot J; Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
    Mikolajczak SA; Center for Infectious Disease Research, Seattle, Washington, United States of America.
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    Źródło:
    PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2017 Jul 31; Vol. 11 (7), pp. e0005791. Date of Electronic Publication: 2017 Jul 31 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Protein Processing, Post-Translational*
    Membrane Proteins/*analysis
    Plasmodium vivax/*isolation & purification
    Proteome/*analysis
    Protozoan Proteins/*analysis
    Animals ; Anopheles/parasitology ; Malaria, Vivax/metabolism ; Mass Spectrometry ; Proteogenomics ; Salivary Glands/parasitology ; Sporozoites/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Identification of pathogen genomic variants through an integrated pipeline.
    Autorzy:
    Manary MJ; Department of Pediatrics, University of California, San Diego, School of Medicine, 9500 Gilman Drive 0741, La Jolla, California 92093, USA. .
    Singhakul SS
    Flannery EL
    Bopp SE
    Corey VC
    Bright AT
    McNamara CW
    Walker JR
    Winzeler EA
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    Źródło:
    BMC bioinformatics [BMC Bioinformatics] 2014 Mar 03; Vol. 15, pp. 63. Date of Electronic Publication: 2014 Mar 03.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Software*
    DNA Copy Number Variations/*genetics
    Genome, Protozoan/*genetics
    Genomics/*methods
    Plasmodium falciparum/*genetics
    Antimalarials/pharmacology ; DNA, Protozoan/genetics ; Drug Resistance/genetics ; Plasmodium falciparum/drug effects ; Polymorphism, Single Nucleotide/genetics ; Sequence Analysis, DNA/methods
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Antimalarial drug discovery - approaches and progress towards new medicines.
    Autorzy:
    Flannery EL; Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive 0741, La Jolla, California 92093, USA.
    Chatterjee AK
    Winzeler EA
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    Źródło:
    Nature reviews. Microbiology [Nat Rev Microbiol] 2013 Dec; Vol. 11 (12), pp. 849-62. Date of Electronic Publication: 2013 Nov 11.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Antimalarials/*isolation & purification
    Antimalarials/*pharmacology
    Drug Discovery/*methods
    Drug Discovery/*trends
    Clinical Trials as Topic ; Drug Evaluation, Preclinical ; Humans
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-9 z 9

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