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Tytuł :
Flumazenil therapy for a gabapentin-induced coma: a case report.
Autorzy :
Masciullo M; Spinal Cord Unit, IRCCS S. Lucia Foundation, Rome, Italy.; SPInal REhabilitation Lab (SPIRE), IRCCS Fondazione Santa Lucia, Rome, Italy.
Pichiorri F; Spinal Cord Unit, IRCCS S. Lucia Foundation, Rome, Italy.
Scivoletto G; Spinal Cord Unit, IRCCS S. Lucia Foundation, Rome, Italy. .; SPInal REhabilitation Lab (SPIRE), IRCCS Fondazione Santa Lucia, Rome, Italy. .
Foti C; Physical and Rehabilitation Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Molinari M; Spinal Cord Unit, IRCCS S. Lucia Foundation, Rome, Italy.
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Źródło :
Journal of medical case reports [J Med Case Rep] 2021 May 09; Vol. 15 (1), pp. 242. Date of Electronic Publication: 2021 May 09.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Coma*/chemically induced
Coma*/drug therapy
Flumazenil*/therapeutic use
Aged ; Antidotes ; Gabapentin/adverse effects ; Humans ; Male ; Quality of Life
Czasopismo naukowe
Tytuł :
Re-sleeping after reversal of remimazolam by flumazenil.
Autorzy :
Yamamoto T; Division of Anesthesiology, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-dori, Chuo ward, Niigata, 951-8510, Japan. .
Kurabe M; Division of Anesthesiology, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-dori, Chuo ward, Niigata, 951-8510, Japan.
Kamiya Y; Division of Anesthesiology, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-dori, Chuo ward, Niigata, 951-8510, Japan.
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Źródło :
Journal of anesthesia [J Anesth] 2021 Apr; Vol. 35 (2), pp. 322. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Letter
MeSH Terms :
Benzodiazepines*
Flumazenil*
Double-Blind Method ; Hypnotics and Sedatives/adverse effects ; Midazolam
Opinia redakcyjna
Tytuł :
[123I]Iomazenil SPECT Detects a Reversible Lesion of the Left Medial Temporal Lobe in a Case of Global Autobiographical Amnesia.
Autorzy :
Sehara Y; Department of Neurology, Haga Red Cross Hospital, Tochigi, Japan.; Division of Genetic Therapeutics, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
Ando Y; Department of Neurology, Haga Red Cross Hospital, Tochigi, Japan.
Minezumi T; Department of Neurology, Haga Red Cross Hospital, Tochigi, Japan.
Funayama N; Section of Community Medicine, Haga Red Cross Hospital, Tochigi, Japan.
Kawai K; Department of Neurosurgery, Jichi Medical University, Tochigi, Japan.
Sawada M; Department of Neurology, Haga Red Cross Hospital, Tochigi, Japan.
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Źródło :
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology [Cogn Behav Neurol] 2021 Mar 03; Vol. 34 (1), pp. 70-75. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Amnesia/*drug therapy
Flumazenil/*analogs & derivatives
Iodine Radioisotopes/*therapeutic use
Magnetic Resonance Imaging/*methods
Temporal Lobe/*drug effects
Tomography, Emission-Computed, Single-Photon/*methods
Female ; Flumazenil/pharmacology ; Flumazenil/therapeutic use ; Humans ; Iodine Radioisotopes/pharmacology ; Middle Aged
Czasopismo naukowe
Tytuł :
Bolus infusion scheme for the adjustment of steady state [ C]Flumazenil levels in the grey matter and in the blood plasma for neuroreceptor imaging.
Autorzy :
Mauler J; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany. Electronic address: .
Heinzel A; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany; Department of Nuclear Medicine, RWTH Aachen University, Aachen, Germany.
Matusch A; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany.
Herzog H; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany.
Neuner I; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany; Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany; JARA - BRAIN - Translational Medicine, Aachen, Germany.
Scheins J; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany.
Wyss C; Department of Psychiatry, Psychotherapy and Psychosomatics, University of Zurich, Zürich, Switzerland.
Dammers J; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany.
Lang M; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany.
Ermert J; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany.
Neumaier B; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany.
Langen KJ; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany; Department of Nuclear Medicine, RWTH Aachen University, Aachen, Germany; JARA - BRAIN - Translational Medicine, Aachen, Germany.
Shah NJ; Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany; JARA - BRAIN - Translational Medicine, Aachen, Germany; Department of Neurology, RWTH Aachen University, Aachen, Germany.
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Źródło :
NeuroImage [Neuroimage] 2020 Nov 01; Vol. 221, pp. 117160. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Flumazenil*/administration & dosage
Flumazenil*/blood
Flumazenil*/pharmacokinetics
GABA Modulators*/administration & dosage
GABA Modulators*/blood
GABA Modulators*/pharmacokinetics
Gray Matter*/diagnostic imaging
Gray Matter*/drug effects
Gray Matter*/metabolism
Magnetic Resonance Imaging*
Positron-Emission Tomography*
Sensory Receptor Cells*/drug effects
Sensory Receptor Cells*/metabolism
White Matter*/diagnostic imaging
White Matter*/drug effects
White Matter*/metabolism
Carbon Radioisotopes/*administration & dosage
Adult ; Humans ; Male ; Multimodal Imaging ; Young Adult
Czasopismo naukowe
Tytuł :
Detection of Transient Increase of Cerebral Blood Flow and Reversible Neuronal Dysfunction by Iodine-123-Iomazenil Single Photon Emission Computed Tomography After Cerebral Hyperperfusion Syndrome After Revascularization Surgery for Moyamoya Disease.
Autorzy :
Yamasaki M; Department of Neurosurgery, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan.
Yoshioka H; Department of Neurosurgery, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan.
Kanemaru K; Department of Neurosurgery, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan.
Yagi T; Department of Neurosurgery, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan.
Hashimoto K; Department of Neurosurgery, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan.
Senbokuya N; Department of Neurosurgery, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan.
Kinouchi H; Department of Neurosurgery, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan. Electronic address: .
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Źródło :
World neurosurgery [World Neurosurg] 2020 Sep; Vol. 141, pp. 335-338. Date of Electronic Publication: 2020 Jun 09.
Typ publikacji :
Case Reports
MeSH Terms :
Cerebral Revascularization*/methods
Cerebrovascular Circulation/*drug effects
Flumazenil/*analogs & derivatives
Moyamoya Disease/*surgery
Anastomosis, Surgical/adverse effects ; Brain/blood supply ; Brain/surgery ; Cerebral Angiography/adverse effects ; Cerebrovascular Circulation/physiology ; Female ; Flumazenil/pharmacology ; Humans ; Magnetic Resonance Imaging/adverse effects ; Middle Aged
Raport
Tytuł :
Adverse Drug Reaction: Midazolam-Induced Extrapyramidal Symptoms: A Case Report.
Autorzy :
McConn MM; From the Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, Rochester, New York.
Gundy JT
Karan SB
Lindenmuth DM
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Źródło :
A&A practice [A A Pract] 2020 Jun; Vol. 14 (8), pp. e01248.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Basal Ganglia Diseases/*chemically induced
Brachial Plexus Block/*methods
Flumazenil/*therapeutic use
Midazolam/*adverse effects
Female ; Flumazenil/administration & dosage ; Fracture Fixation, Internal/methods ; GABA Modulators/administration & dosage ; GABA Modulators/therapeutic use ; Humans ; Hypnotics and Sedatives/adverse effects ; Middle Aged ; Open Fracture Reduction/methods ; Radius Fractures/surgery ; Treatment Outcome ; Ultrasonography, Interventional/instrumentation
Czasopismo naukowe
Tytuł :
Video NeuroImages: Idiopathic Recurring Stupor: An Unusual Clinical Condition Responding to Flumazenil.
Autorzy :
Gómez García A; From the Department of Neurology, Fundación Jiménez Dïaz, Madrid, Spain. .
Navas Vinagre I; From the Department of Neurology, Fundación Jiménez Dïaz, Madrid, Spain.
Herranz Bárcenas A; From the Department of Neurology, Fundación Jiménez Dïaz, Madrid, Spain.
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Źródło :
Neurology [Neurology] 2021 Mar 23; Vol. 96 (12), pp. 586. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Case Reports; Journal Article; Video-Audio Media
MeSH Terms :
Flumazenil/*therapeutic use
GABA Modulators/*therapeutic use
Stupor/*diagnosis
Stupor/*drug therapy
Aged ; Chronic Disease ; Female ; Humans
Czasopismo naukowe
Tytuł :
How does α 1 Histidine102 affect the binding of modulators to α 1 β 2 γ 2 GABA A receptors? molecular insights from in silico experiments.
Autorzy :
Amundarain MJ; Instituto de Física del Sur (IFISUR), Departamento de Física, Universidad Nacional del Sur (UNS), CONICET, Av. L. N. Alem 1253, B8000CPB - Bahía Blanca, Argentina. .
Caffarena ER; Programa de Computação Científica - PROCC, Fundação Oswaldo Cruz, Manguinhos, CEP 21040-360, Av. Brasil 4365, Rio de Janeiro, RJ, Brazil.
Costabel MD; Instituto de Física del Sur (IFISUR), Departamento de Física, Universidad Nacional del Sur (UNS), CONICET, Av. L. N. Alem 1253, B8000CPB - Bahía Blanca, Argentina. .
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Źródło :
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2021 Feb 19; Vol. 23 (6), pp. 3993-4006.
Typ publikacji :
Journal Article
MeSH Terms :
Diazepam/*metabolism
Flumazenil/*metabolism
GABA Modulators/*metabolism
GABA-A Receptor Antagonists/*metabolism
Receptors, GABA-A/*metabolism
Histidine/chemistry ; Humans ; Molecular Dynamics Simulation ; Protein Conformation ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Protons ; Receptors, GABA-A/chemistry
Czasopismo naukowe
Tytuł :
Flumazenil-insensitive benzodiazepine binding sites in GABA A receptors contribute to benzodiazepine-induced immobility in zebrafish larvae.
Autorzy :
Cao Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Yan H; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Yu G; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China. Electronic address: .
Su R; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2019 Dec 15; Vol. 239, pp. 117033. Date of Electronic Publication: 2019 Nov 04.
Typ publikacji :
Journal Article
MeSH Terms :
Benzodiazepines/*metabolism
Benzodiazepines/*pharmacology
Flumazenil/*pharmacology
GABA Modulators/*pharmacology
Motor Activity/*drug effects
Receptors, GABA-A/*drug effects
Animals ; Azides/pharmacology ; Benzodiazepines/toxicity ; Bicuculline/pharmacology ; Binding Sites/drug effects ; Clonazepam/pharmacology ; Dose-Response Relationship, Drug ; Female ; Flumazenil/toxicity ; GABA Antagonists/pharmacology ; GABA Modulators/toxicity ; Larva ; Male ; Zebrafish
Czasopismo naukowe
Tytuł :
Use of Rodent Sedation Tests to Evaluate Midazolam and Flumazenil in Green Iguanas ( Iguana iguana ).
Autorzy :
Bressan TF; Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering - University of São Paulo, Brazil.
Sobreira T; Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering - University of São Paulo, Brazil.
Carregaro AB; Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering - University of São Paulo, Brazil;, Email: .
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Źródło :
Journal of the American Association for Laboratory Animal Science : JAALAS [J Am Assoc Lab Anim Sci] 2019 Nov 01; Vol. 58 (6), pp. 810-816. Date of Electronic Publication: 2019 Oct 23.
Typ publikacji :
Clinical Trial, Veterinary; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Iguanas*
Flumazenil/*pharmacology
Hypnotics and Sedatives/*pharmacology
Midazolam/*pharmacology
Animals ; Antidotes/administration & dosage ; Antidotes/pharmacology ; Female ; Flumazenil/administration & dosage ; Laboratory Animal Science ; Male ; Midazolam/administration & dosage
Czasopismo naukowe
Tytuł :
The GABA A -Benzodiazepine Receptor Antagonist Flumazenil Abolishes the Anxiolytic Effects of the Active Constituents of Crocus sativus L. Crocins in Rats.
Autorzy :
Pitsikas N; Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Panepistimiou 3, 415-00 Larissa, Greece.
Tarantilis PA; Laboratory of Chemistry, Department of Food Science and Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, 118-55 Athens, Greece.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Nov 30; Vol. 25 (23). Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Anxiety Agents/*pharmacology
Anxiety/*drug therapy
Benzodiazepines/*metabolism
Carotenoids/*toxicity
Crocus/*chemistry
Flumazenil/*pharmacology
GABA-A Receptor Antagonists/*pharmacology
Animals ; Anxiety/chemically induced ; Anxiety/metabolism ; Anxiety/pathology ; Behavior, Animal/drug effects ; Male ; Plant Extracts/toxicity ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
EVALUATION OF THE EFFECTS OF MIDAZOLAM AND FLUMAZENIL IN THE BALL PYTHON ( PYTHON REGIUS ).
Autorzy :
Larouche CB; Departments of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada, .; Toronto Zoo, Toronto, Ontario M1B 5K7, Canada.
Beaufrère H; Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Mosley C; VCA Canada, 404 Veterinary Emergency and Referral Hospital, Newmarket, Ontario L3Y 0B3, Canada.
Nemeth NM; Departments of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.; Toronto Zoo, Toronto, Ontario M1B 5K7, Canada.
Dutton C; Toronto Zoo, Toronto, Ontario M1B 5K7, Canada.
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Źródło :
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians [J Zoo Wildl Med] 2019 Sep; Vol. 50 (3), pp. 579-588.
Typ publikacji :
Journal Article; Randomized Controlled Trial, Veterinary
MeSH Terms :
Boidae*
Flumazenil/*pharmacology
GABA Modulators/*pharmacology
Hypnotics and Sedatives/*pharmacology
Midazolam/*pharmacology
Animals ; Cross-Over Studies ; Female ; Flumazenil/administration & dosage ; GABA Modulators/administration & dosage ; Hypnotics and Sedatives/administration & dosage ; Midazolam/administration & dosage
Czasopismo naukowe
Tytuł :
Long-Term Outcomes of Cerebral Blood Flow and Neurotransmitter Receptor Function on Iodine-123-Iomazenil Single-Photon Emission Computed Tomography and Cognitive Assessments After Parent Artery Occlusion Combined with Cerebral Revascularization for Internal Carotid Artery Aneurysms.
Autorzy :
Kubo Y; Department of Neurosurgery, Iwate Medical University, Morioka, Japan. Electronic address: .
Koji T; Department of Neurosurgery, Iwate Medical University, Morioka, Japan.
Murakami T; Department of Neurosurgery, Iwate Medical University, Morioka, Japan.
Yoshida K; Department of Neurosurgery, Iwate Medical University, Morioka, Japan.
Matsumoto Y; Department of Neurosurgery, Iwate Medical University, Morioka, Japan.
Ogasawara K; Department of Neurosurgery, Iwate Medical University, Morioka, Japan.
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Źródło :
World neurosurgery [World Neurosurg] 2020 Nov; Vol. 143, pp. e199-e205. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Cerebral Revascularization*
Brain/*diagnostic imaging
Carotid Artery Diseases/*surgery
Carotid Artery, Internal/*surgery
Cerebrovascular Circulation/*physiology
Cognition/*physiology
Intracranial Aneurysm/*surgery
Receptors, GABA-A/*metabolism
Aged ; Aged, 80 and over ; Brain/blood supply ; Brain/metabolism ; Female ; Flumazenil/analogs & derivatives ; Humans ; Longitudinal Studies ; Middle Aged ; Middle Cerebral Artery/surgery ; Prospective Studies ; Saphenous Vein/transplantation ; Temporal Arteries/surgery ; Tomography, Emission-Computed, Single-Photon ; Treatment Outcome ; Vascular Grafting
Czasopismo naukowe
Tytuł :
Chemical Composition of Essential Oil from Flower of 'Shanzhizi' ( Gardenia jasminoides Ellis) and Involvement of Serotonergic System in Its Anxiolytic Effect.
Autorzy :
Zhang N; Department of Landscape Architecture, School of Design, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200241, China.
Luo M; Department of Landscape Architecture, School of Design, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200241, China.
He L; Department of Resources and Environment, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200241, China.
Yao L; Department of Landscape Architecture, School of Design, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200241, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Oct 14; Vol. 25 (20). Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Anxiety Agents/*pharmacology
Gardenia/*chemistry
Oils, Volatile/*chemistry
Oils, Volatile/*pharmacology
Administration, Inhalation ; Animals ; Anti-Anxiety Agents/administration & dosage ; Anti-Anxiety Agents/chemistry ; Biogenic Monoamines/analysis ; Cyclohexanes/pharmacology ; Disease Models, Animal ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacology ; Elevated Plus Maze Test ; Flumazenil/pharmacology ; Gas Chromatography-Mass Spectrometry ; Hypnotics and Sedatives/administration & dosage ; Hypnotics and Sedatives/chemistry ; Hypnotics and Sedatives/pharmacology ; Male ; Mice, Inbred ICR ; Oils, Volatile/administration & dosage ; Pentobarbital/pharmacology ; Piperazines/pharmacology ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/metabolism ; Receptors, Neurotransmitter/antagonists & inhibitors ; Sleep/drug effects ; Sulpiride/pharmacology ; Synaptic Transmission/drug effects
Czasopismo naukowe
Tytuł :
Anxiolytic properties of Cymbopogon citratus (DC.) stapf extract, essential oil and its constituents in zebrafish (Danio rerio).
Autorzy :
Mendes Hacke AC; Departamento de Química, Universidade Estadual de Ponta Grossa, UEPG, Ponta Grossa, Brazil. Electronic address: .
Miyoshi E; Departamento de Ciências Farmacêuticas, Universidade Estadual de Ponta Grossa, UEPG, Ponta Grossa, Brazil. Electronic address: .
Marques JA; Departamento de Química, Universidade Estadual de Ponta Grossa, UEPG, Ponta Grossa, Brazil. Electronic address: .
Pereira RP; Departamento de Química, Universidade Estadual de Ponta Grossa, UEPG, Ponta Grossa, Brazil. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2020 Oct 05; Vol. 260, pp. 113036. Date of Electronic Publication: 2020 May 28.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anti-Anxiety Agents/*pharmacology
Cymbopogon/*chemistry
Oils, Volatile/*pharmacology
Plant Extracts/*pharmacology
Animals ; Anti-Anxiety Agents/chemistry ; Anti-Anxiety Agents/isolation & purification ; Anxiety/drug therapy ; Behavior, Animal/drug effects ; Disease Models, Animal ; Flumazenil/pharmacology ; Medicine, Traditional ; Oils, Volatile/chemistry ; Oils, Volatile/isolation & purification ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Plant Leaves ; Receptors, GABA-A/drug effects ; Receptors, GABA-A/metabolism ; Zebrafish
Czasopismo naukowe
Tytuł :
Early-stage C-Flumazenil PET predicts day-14 selective neuronal loss in a rodent model of transient focal cerebral ischemia.
Autorzy :
Hughes JL; Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Beech JS; Division of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge, UK.
Jones PS; Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Wang D; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Menon DK; Division of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge, UK.
Aigbirhio FI; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Fryer TD; Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Baron JC; Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Inserm U1266, Paris Descartes University, Sainte-Anne Hospital, Paris, France.
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Źródło :
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2020 Oct; Vol. 40 (10), pp. 1997-2009. Date of Electronic Publication: 2019 Oct 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ischemic Attack, Transient/*diagnostic imaging
Neurons/*pathology
Positron-Emission Tomography/*methods
Animals ; Antigens, Nuclear/metabolism ; Cerebral Infarction/diagnostic imaging ; Cerebral Infarction/pathology ; Female ; Flumazenil ; Immunohistochemistry ; Infarction, Middle Cerebral Artery/diagnostic imaging ; Infarction, Middle Cerebral Artery/pathology ; Ischemic Attack, Transient/pathology ; Male ; Nerve Tissue Proteins/metabolism ; Predictive Value of Tests ; Radiopharmaceuticals ; Rats ; Rats, Inbred SHR ; Receptors, GABA-A/drug effects ; Receptors, GABA-A/metabolism
Czasopismo naukowe
Tytuł :
Quantitative Analysis of [18F]FFMZ and [18F]FDG PET Studies in the Localization of Seizure Onset Zone in Drug-Resistant Temporal Lobe Epilepsy.
Autorzy :
Avendaño-Estrada A; Unidad Radiofarmacia-Ciclotrón, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Velasco F; Unit for Stereotactic and Functional Neurosurgery, Hospital General de México, Mexico City, Mexico.
Velasco AL; Unit for Stereotactic and Functional Neurosurgery, Hospital General de México, Mexico City, Mexico.
Cuellar-Herrera M; Unit for Stereotactic and Functional Neurosurgery, Hospital General de México, Mexico City, Mexico.
Saucedo-Alvarado PE; Unit for Stereotactic and Functional Neurosurgery, Hospital General de México, Mexico City, Mexico.
Marquez-Franco R; Unit for Stereotactic and Functional Neurosurgery, Hospital General de México, Mexico City, Mexico.
Rivera-Bravo B; Unidad PET/CT, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Ávila-Rodríguez MA; Unidad Radiofarmacia-Ciclotrón, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico, .
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Źródło :
Stereotactic and functional neurosurgery [Stereotact Funct Neurosurg] 2019; Vol. 97 (4), pp. 232-240. Date of Electronic Publication: 2019 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fluorine Radioisotopes*/metabolism
Fluorodeoxyglucose F18*/metabolism
Drug Resistant Epilepsy/*diagnostic imaging
Epilepsy, Temporal Lobe/*diagnostic imaging
Flumazenil/*analogs & derivatives
Positron-Emission Tomography/*methods
Adolescent ; Adult ; Brain Mapping/methods ; Drug Resistant Epilepsy/metabolism ; Drug Resistant Epilepsy/surgery ; Epilepsy, Temporal Lobe/metabolism ; Epilepsy, Temporal Lobe/surgery ; Female ; Flumazenil/metabolism ; Humans ; Male ; Middle Aged ; Seizures/diagnostic imaging ; Seizures/metabolism ; Seizures/surgery
Czasopismo naukowe
Tytuł :
Anti-Epileptic Effects of FABP3 Ligand MF1 through the Benzodiazepine Recognition Site of the GABA A Receptor.
Autorzy :
Yabuki Y; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.; Department of Genomic Neurology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan.
Liu J; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Kawahata I; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Izumi H; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Shinoda Y; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Koga K; Department of Neurophysiology, Hyogo College of Medicine, Nishinomiya 663-8501, Japan.; Department of Neurophysiology, Graduate School of Medicine, Hirosaki University, Hirosaki 036-8216, Japan.
Ueno S; Department of Neurophysiology, Graduate School of Medicine, Hirosaki University, Hirosaki 036-8216, Japan.
Shioda N; Department of Genomic Neurology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan.
Fukunaga K; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 01; Vol. 21 (15). Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article
MeSH Terms :
Anticonvulsants/*pharmacology
Benzodiazepines/*pharmacology
Fatty Acid Binding Protein 3/*metabolism
Receptors, GABA-A/*metabolism
Status Epilepticus/*drug therapy
Animals ; Anticonvulsants/chemistry ; Anticonvulsants/metabolism ; Benzodiazepines/metabolism ; Binding Sites ; Cell Line, Tumor ; Diazepam/metabolism ; Diazepam/pharmacology ; Flumazenil/metabolism ; Flumazenil/pharmacology ; Ligands ; Male ; Mice, Inbred ICR ; Pentylenetetrazole/metabolism ; Pentylenetetrazole/pharmacology ; Seizures/drug therapy ; Seizures/metabolism ; Status Epilepticus/metabolism
Czasopismo naukowe
Tytuł :
Postoperative expressive aphasia associated with intravenous midazolam administration: a 5-year retrospective case-control study.
Autorzy :
Oh S; Department of Anesthesiology and Pain Medicine, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Chung J; Department of Anesthesiology and Pain Medicine, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Baek S; Department of Anesthesiology and Pain Medicine, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Park YJ; Department of Anesthesiology and Pain Medicine, Saint Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
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Źródło :
The Journal of international medical research [J Int Med Res] 2020 Aug; Vol. 48 (8), pp. 300060520948751.
Typ publikacji :
Journal Article
MeSH Terms :
Aphasia, Broca*
Midazolam*/adverse effects
Aged ; Case-Control Studies ; Double-Blind Method ; Female ; Flumazenil/therapeutic use ; Humans ; Male ; Retrospective Studies
Czasopismo naukowe

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