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Tytuł:
Effectiveness of artemether-lumefantrine for treating uncomplicated malaria in low- and high-transmission areas of Ghana.
Autorzy:
Mawuli MA; West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), College of Basic and Applied Sciences, University of Ghana, Legon, Accra, Ghana. .; Department of Pathology, University of Ghana Medical School, College of Health Sciences, University of Ghana, Korle-Bu, Accra, Ghana. .
Amoah LE; Department of Immunology, Noguchi Memorial Institute for Medical Research College of Health Sciences, University of Ghana, Legon, Accra, Ghana.
Cui L; Department of Internal Medicine, University of South Florida, 3720 Spectrum Blvd, Tampa, FL, 33612, USA.
Quashie NB; West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), College of Basic and Applied Sciences, University of Ghana, Legon, Accra, Ghana.; Department of Epidemiology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, Ghana.; Centre for Tropical Clinical Pharmacology and Therapeutics, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana.
Afrane YA; Department of Medical Microbiology, University of Ghana Medical School College of Health Sciences, University of Ghana, Korle-Bu, Accra, Ghana.
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Źródło:
Malaria journal [Malar J] 2024 Feb 05; Vol. 23 (1), pp. 40. Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials*/therapeutic use
Artemisinins*/therapeutic use
Malaria, Falciparum*/drug therapy
Humans ; Artemether, Lumefantrine Drug Combination/therapeutic use ; Ghana ; Drug Combinations ; Artemether/therapeutic use ; Recurrence ; Parasitemia/drug therapy ; Ethanolamines/therapeutic use ; Fluorenes/therapeutic use ; Plasmodium falciparum/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy and safety of pyronaridine-artesunate versus artemether-lumefantrine in the treatment of acute uncomplicated malaria in children in South-West Nigeria: an open-labelled randomized controlled trial.
Autorzy:
Falade CO; Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria. .; Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria. .
Orimadegun AE; Institute of Child Health, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Olusola FI; Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Michael OS; Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Anjorin OE; Department of Accident and Emergency, Obafemi Awolowo University Teaching, Hospital, Ile-Ife, Nigeria.
Funwei RI; Department of Pharmacology, Babcock University, Ilisan, Remo, Ogun State, Nigeria.
Adedapo AD; Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Olusanya AL; Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Orimadegun BE; Department of Chemical Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Mokuolu OA; Department of Paediatrics, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
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Źródło:
Malaria journal [Malar J] 2023 May 13; Vol. 22 (1), pp. 154. Date of Electronic Publication: 2023 May 13.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Antimalarials*/adverse effects
Artemisinins*/adverse effects
Malaria, Falciparum*/drug therapy
Humans ; Child ; Male ; Infant ; Female ; Artemether, Lumefantrine Drug Combination/therapeutic use ; Nigeria ; Retrospective Studies ; Artemether/therapeutic use ; Drug Combinations ; Ethanolamines/therapeutic use ; Treatment Outcome ; Fluorenes/adverse effects
SCR Disease Name:
Acute malaria
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Artemether-lumefantrine efficacy among adults on antiretroviral therapy in Malawi.
Autorzy:
Nyangulu W; Dignitas International, Zomba, Malawi.; Public Health and Nutrition Research Group, Kamuzu University of Health Sciences, Mangochi, Malawi.
Mungwira RG; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi.
Divala TH; Dignitas International, Zomba, Malawi.
Nampota-Nkomba N; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi.
Nyirenda OM; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi.
Buchwald AG; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., Baltimore, MD, 21201, USA.
Miller J; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., Baltimore, MD, 21201, USA.
Earland DE; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., Baltimore, MD, 21201, USA.
Adams M; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., Baltimore, MD, 21201, USA.
Plowe CV; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., Baltimore, MD, 21201, USA.
Taylor TE; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi.; Michigan State University, East Lansing, USA.
Mallewa JE; Department of Medicine, Kamuzu University of Health Sciences, Blantyre, Malawi.
van Oosterhout JJ; Dignitas International, Zomba, Malawi.; Partners in Hope, Lilongwe Malawi and David Geffen School of Medicine, University of California, Los Angeles, USA.
Parikh S; Yale School of Public Health, New Haven, USA.
Laurens MB; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., Baltimore, MD, 21201, USA.
Laufer MK; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., Baltimore, MD, 21201, USA. .
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Corporate Authors:
TSCQ Study Team
Źródło:
Malaria journal [Malar J] 2023 Jan 27; Vol. 22 (1), pp. 32. Date of Electronic Publication: 2023 Jan 27.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Antimalarials*/therapeutic use
Artemisinins*/therapeutic use
Malaria*/drug therapy
Malaria, Falciparum*/drug therapy
Malaria, Falciparum*/prevention & control
HIV Infections*/drug therapy
Humans ; Adult ; Malawi ; Artemether/therapeutic use ; Drug Combinations ; Artemether, Lumefantrine Drug Combination/therapeutic use ; Lumefantrine/therapeutic use ; Treatment Outcome ; Ethanolamines/therapeutic use ; Fluorenes/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Safety and therapeutic efficacy of artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria at Shecha health centre, Arba Minch, Ethiopia.
Autorzy:
Gubae K; Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.; Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Mohammed H; Malaria and Other Parasitological and Entomological Research Team, Bacterial, Parasitic and Zoonotic Diseases Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Sime H; Malaria and Other Parasitological and Entomological Research Team, Bacterial, Parasitic and Zoonotic Diseases Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Hailgiorgis H; Malaria and Other Parasitological and Entomological Research Team, Bacterial, Parasitic and Zoonotic Diseases Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Mare AK; Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Gidey B; Malaria and Other Parasitological and Entomological Research Team, Bacterial, Parasitic and Zoonotic Diseases Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Haile M; Ethiopian Ministry of Health, Addis Ababa, Ethiopia.
Assefa G; Ethiopian Ministry of Health, Addis Ababa, Ethiopia.
Bekele W; World Health Organization, Addis Ababa, Ethiopia.
Tasew G; Malaria and Other Parasitological and Entomological Research Team, Bacterial, Parasitic and Zoonotic Diseases Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Abay SM; Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia. .
Assefa A; Malaria and Other Parasitological and Entomological Research Team, Bacterial, Parasitic and Zoonotic Diseases Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.; Institute of Infectious Disease and Global Health, University of North Carolina at Chapel Hill, Chapel Hill, USA.
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Źródło:
Malaria journal [Malar J] 2023 Jan 07; Vol. 22 (1), pp. 9. Date of Electronic Publication: 2023 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials*/adverse effects
Artemisinins*/adverse effects
Malaria, Falciparum*/epidemiology
Humans ; Infant ; Artemether, Lumefantrine Drug Combination/therapeutic use ; Ethiopia/epidemiology ; Artemether/therapeutic use ; Plasmodium falciparum ; Drug Combinations ; Fluorenes/adverse effects ; Treatment Outcome ; Ethanolamines/adverse effects ; Fever/drug therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Modelling the optimal dosing schedule for artemether-lumefantrine chemoprophylaxis against malaria.
Autorzy:
Tarning J; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
von Seidlein L; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Dondorp AM; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
White NJ; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Maude RJ; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. .; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK. .; Harvard TH Chan School of Public Health, Harvard University, Boston, USA. .; The Open University, Milton Keynes, UK. .
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Źródło:
BMC research notes [BMC Res Notes] 2022 Oct 02; Vol. 15 (1), pp. 313. Date of Electronic Publication: 2022 Oct 02.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Antimalarials*/therapeutic use
Artemisinins*/therapeutic use
Malaria*/drug therapy
Malaria*/prevention & control
Malaria, Falciparum*/drug therapy
Malaria, Falciparum*/prevention & control
Artemether/therapeutic use ; Artemether, Lumefantrine Drug Combination/therapeutic use ; Chemoprevention ; Drug Combinations ; Ethanolamines ; Fluorenes/therapeutic use ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Quinine plus clindamycin vs artemether-lumefantrine for treatment of uncomplicated falciparum malaria in western Kenya.
Autorzy:
Obonyo CO; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya. .
Ogutu BR; Centre for Clinical Research, Kenya Medical Research Institute, P.O. Box 20778, Nairobi, Kenya.
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Źródło:
Malaria journal [Malar J] 2022 Jun 21; Vol. 21 (1), pp. 198. Date of Electronic Publication: 2022 Jun 21.
Typ publikacji:
Letter
MeSH Terms:
Antimalarials*/therapeutic use
Malaria, Falciparum*/drug therapy
Artemether/therapeutic use ; Artemether, Lumefantrine Drug Combination/therapeutic use ; Clindamycin/therapeutic use ; Drug Combinations ; Ethanolamines/therapeutic use ; Fluorenes/therapeutic use ; Humans ; Kenya ; Quinine/therapeutic use
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Need for optimized dosages in the design of comparative clinical trials of anti-malarial drugs.
Autorzy:
Krishna S; Centre for Diagnostics and Antimicrobial Resistance, Institute for Infection and Immunity, St George's University of London, London, UK.; Institut für Tropenmedizin, Universitätsklinikum Tübingen, Tübingen, Germany.
Kremsner PG; Institut für Tropenmedizin, Universitätsklinikum Tübingen, Tübingen, Germany. .; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon. .
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Źródło:
Malaria journal [Malar J] 2022 Jun 20; Vol. 21 (1), pp. 194. Date of Electronic Publication: 2022 Jun 20.
Typ publikacji:
Letter
MeSH Terms:
Antimalarials*/therapeutic use
Artemisinins*/therapeutic use
Malaria*/drug therapy
Malaria, Falciparum*/drug therapy
Drug Combinations ; Ethanolamines/therapeutic use ; Fluorenes/therapeutic use ; Humans ; Quinine/therapeutic use ; Treatment Outcome
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women.
Autorzy:
Mutagonda RF; Department of Clinical Pharmacy and Pharmacology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, P.O. Box 65013, Dar es Salaam, Tanzania. .
Kamuhabwa AAR; Department of Clinical Pharmacy and Pharmacology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, P.O. Box 65013, Dar es Salaam, Tanzania.
Minzi OMS; Department of Clinical Pharmacy and Pharmacology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, P.O. Box 65013, Dar es Salaam, Tanzania.
Massawe SN; Department of Obstetrics and Gynaecology, School of Medicine, Muhimbili University of Allied Sciences, P.O Box 65013, Dar es Salaam, Tanzania.
Asghar M; Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Solna, 171 76, Stockholm, Sweden.
Homann MV; Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Solna, 171 76, Stockholm, Sweden.
Färnert A; Unit of Infectious Diseases, Department of Medicine, Karolinska Institutet, Solna, 171 76, Stockholm, Sweden.; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
Aklillu E; Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77, Stockholm, Sweden.
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Źródło:
Malaria journal [Malar J] 2017 Jul 03; Vol. 16 (1), pp. 267. Date of Electronic Publication: 2017 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials/*pharmacokinetics
Ethanolamines/*pharmacokinetics
Fluorenes/*pharmacokinetics
Malaria, Falciparum/*drug therapy
Pregnancy Complications, Parasitic/*drug therapy
ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; Adolescent ; Adult ; Alleles ; Antimalarials/blood ; Antimalarials/therapeutic use ; Aryl Hydrocarbon Hydroxylases/genetics ; Cohort Studies ; Cytochrome P-450 CYP2B6/genetics ; Cytochrome P-450 CYP3A/genetics ; Cytochrome P450 Family 2/genetics ; Ethanolamines/blood ; Ethanolamines/therapeutic use ; Female ; Fluorenes/blood ; Fluorenes/therapeutic use ; Gene Frequency ; Genotype ; Haplotypes ; Humans ; Lumefantrine ; Malaria, Falciparum/genetics ; Malaria, Falciparum/metabolism ; Pharmacogenetics ; Pregnancy ; Pregnancy Complications, Parasitic/genetics ; Pregnancy Complications, Parasitic/metabolism ; Pregnancy Trimester, Second ; Pregnancy Trimester, Third ; Prospective Studies ; Steroid Hydroxylases/genetics ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Engineering of microcomplex of artemether and lumefantrine for effective drug treatment in malaria.
Autorzy:
Shende P; a Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management , SVKM's NMIMS University , Mumbai , India.
Desai P; a Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management , SVKM's NMIMS University , Mumbai , India.
Gaud RS; a Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management , SVKM's NMIMS University , Mumbai , India.
Dhumatkar R; a Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management , SVKM's NMIMS University , Mumbai , India.
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Źródło:
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2017 Dec; Vol. 45 (8), pp. 1597-1604. Date of Electronic Publication: 2016 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials/*chemistry
Artemisinins/*chemistry
Drug Carriers/*chemistry
Ethanolamines/*chemistry
Fluorenes/*chemistry
Malaria/*drug therapy
Antimalarials/therapeutic use ; Artemether ; Artemisinins/therapeutic use ; Citric Acid/chemistry ; Drug Interactions ; Drug Liberation ; Ethanolamines/therapeutic use ; Fluorenes/therapeutic use ; Lumefantrine ; Microspheres ; Particle Size ; Pyrrolidines/chemistry ; Vinyl Compounds/chemistry ; beta-Cyclodextrins/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Community-led Responses for Elimination (CoRE): a study protocol for a community randomized controlled trial assessing the effectiveness of community-level, reactive focal drug administration for reducing Plasmodium falciparum infection prevalence and incidence in Southern Province, Zambia.
Autorzy:
Bridges DJ; PATH-Malaria Control and Elimination Partnership in Africa (MACEPA), National Malaria Control Centre, Chainama Hospital College Grounds, Lusaka, Zambia. .
Miller JM; PATH-Malaria Control and Elimination Partnership in Africa (MACEPA), National Malaria Control Centre, Chainama Hospital College Grounds, Lusaka, Zambia.
Chalwe V; Zambia Ministry of Health, Provincial Medical Office, Mansa, Luapula Province, Zambia.
Moonga H; National Malaria Control Centre, Zambia Ministry of Health, Chainama Hospital, Lusaka, Zambia.
Hamainza B; National Malaria Control Centre, Zambia Ministry of Health, Chainama Hospital, Lusaka, Zambia.
Steketee R; PATH-Malaria Control and Elimination Partnership in Africa (MACEPA), 2201 Westlake Avenue, Seattle, WA, USA.
Silumbe K; PATH-Malaria Control and Elimination Partnership in Africa (MACEPA), National Malaria Control Centre, Chainama Hospital College Grounds, Lusaka, Zambia.
Nyangu J; PATH-Malaria Control and Elimination Partnership in Africa (MACEPA), National Malaria Control Centre, Chainama Hospital College Grounds, Lusaka, Zambia.
Larsen DA; Syracuse University Department of Public Health, Food Studies and Nutrition, Syracuse, NY, USA.
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Źródło:
Trials [Trials] 2017 Nov 02; Vol. 18 (1), pp. 511. Date of Electronic Publication: 2017 Nov 02.
Typ publikacji:
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms:
Antimalarials/*administration & dosage
Artemisinins/*administration & dosage
Ethanolamines/*administration & dosage
Fluorenes/*administration & dosage
Malaria, Falciparum/*prevention & control
Plasmodium falciparum/*drug effects
Quinolines/*administration & dosage
Adolescent ; Adult ; Antimalarials/adverse effects ; Artemether, Lumefantrine Drug Combination ; Artemisinins/adverse effects ; Child ; Child, Preschool ; Clinical Protocols ; Community Health Services ; Drug Administration Schedule ; Drug Combinations ; Ethanolamines/adverse effects ; Female ; Fluorenes/adverse effects ; Humans ; Incidence ; Infant ; Malaria, Falciparum/diagnosis ; Malaria, Falciparum/epidemiology ; Malaria, Falciparum/parasitology ; Male ; Middle Aged ; Plasmodium falciparum/pathogenicity ; Prevalence ; Quinolines/adverse effects ; Research Design ; Risk Factors ; Time Factors ; Treatment Outcome ; Young Adult ; Zambia/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cost-effectiveness of artemisinin-naphthoquine versus artemether-lumefantrine for the treatment of uncomplicated malaria in Papua New Guinean children.
Autorzy:
Moore BR; School of Pharmacy, Curtin University of Technology, Perth, WA, Australia.; School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia.
Davis WA; School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia.
Clarke PM; Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.
Robinson LJ; Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea.; Burnet Institute, Parkville, Melbourne, VIC, Australia.; Division of Population Health and Immunity, Walter and Eliza Hall Institute, Parkville, VIC, Australia.
Laman M; Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea.
Davis TME; School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia. .
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Źródło:
Malaria journal [Malar J] 2017 Oct 30; Vol. 16 (1), pp. 438. Date of Electronic Publication: 2017 Oct 30.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Cost-Benefit Analysis*
Antimalarials/*economics
Artemisinins/*economics
Ethanolamines/*economics
Fluorenes/*economics
Malaria, Falciparum/*economics
Malaria, Vivax/*economics
Naphthoquinones/*economics
Randomized Controlled Trials as Topic/*statistics & numerical data
Antimalarials/therapeutic use ; Artemether, Lumefantrine Drug Combination ; Artemisinins/therapeutic use ; Child, Preschool ; Drug Combinations ; Ethanolamines/therapeutic use ; Female ; Fluorenes/therapeutic use ; Humans ; Infant ; Malaria, Falciparum/drug therapy ; Malaria, Vivax/drug therapy ; Male ; Naphthoquinones/therapeutic use ; Papua New Guinea ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Concomitant nevirapine impacts pharmacokinetic exposure to the antimalarial artemether-lumefantrine in African children.
Autorzy:
Huang L; Drug Research Unit, Department of Clinical Pharmacy, University of California, San Francisco, CA, United States of America.
Carey V; Center for Biostatistics in AIDS Research, Harvard TH Chan School of Public Health, Boston, MA, United States of America.
Lindsey JC; Center for Biostatistics in AIDS Research, Harvard TH Chan School of Public Health, Boston, MA, United States of America.
Marzan F; Drug Research Unit, Department of Clinical Pharmacy, University of California, San Francisco, CA, United States of America.
Gingrich D; Drug Research Unit, Department of Clinical Pharmacy, University of California, San Francisco, CA, United States of America.
Graham B; Frontier Science and Technology Research Foundation, Buffalo, NY, United States of America.
Barlow-Mosha L; Makerere University, MUJHU Research Collaboration, Kampala, Uganda.
Ssemambo PK; Makerere University, MUJHU Research Collaboration, Kampala, Uganda.
Kamthunzi P; Kamuzu Central Hospital, Private Bag A-104, Lilongwe, Malawi.
Nachman S; School of Medicine, Stony Brook University, Stony Brook, NY, United States of America.
Parikh S; Yale School of Public Health, New Haven, CT, United States of America.
Aweeka FT; Drug Research Unit, Department of Clinical Pharmacy, University of California, San Francisco, CA, United States of America.
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Corporate Authors:
IMPAACT P1079 protocol team
Źródło:
PloS one [PLoS One] 2017 Oct 24; Vol. 12 (10), pp. e0186589. Date of Electronic Publication: 2017 Oct 24 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials/*pharmacokinetics
Artemisinins/*pharmacokinetics
Ethanolamines/*pharmacokinetics
Fluorenes/*pharmacokinetics
Nevirapine/*therapeutic use
Africa South of the Sahara ; Artemether ; Artemisinins/administration & dosage ; Child ; Child, Preschool ; Ethanolamines/administration & dosage ; Female ; Fluorenes/administration & dosage ; Humans ; Lumefantrine ; Male
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The drug transporter ABCB1 c.3435C>T SNP influences artemether-lumefantrine treatment outcome.
Autorzy:
Kiaco K; Unidade de Parasitologia Médica, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal. .; Serviços de Saúde das Forças Armadas Angolanas, Estado Maior General das Forças Armadas, Luanda, Angola. .
Rodrigues AS; Centre for Toxicogenomics and Human Health, Genetics, Oncology and Human Toxicology, Universidade Nova de Lisboa, Lisbon, Portugal.
do Rosário V; Unidade de Parasitologia Médica, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.
Gil JP; Drug Resistance Unit, Division of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Lopes D; Global Health and Tropical Medicine (GHTM), Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.; Center for Biodiversity, Functional and Integrative Genomics, Faculdade de Ciências, Universidade de Lisboa, Lisbon, Portugal.
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Źródło:
Malaria journal [Malar J] 2017 Sep 21; Vol. 16 (1), pp. 383. Date of Electronic Publication: 2017 Sep 21.
Typ publikacji:
Journal Article
MeSH Terms:
Genotype*
Polymorphism, Single Nucleotide*
Antimalarials/*pharmacology
Artemisinins/*pharmacology
Ethanolamines/*pharmacology
Fluorenes/*pharmacology
Malaria/*drug therapy
ATP Binding Cassette Transporter, Subfamily B/genetics ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; Angola ; Antimalarials/pharmacokinetics ; Artemether, Lumefantrine Drug Combination ; Artemisinins/pharmacokinetics ; Cytochrome P-450 CYP3A/genetics ; Cytochrome P-450 CYP3A/metabolism ; Drug Combinations ; Ethanolamines/pharmacokinetics ; Fluorenes/pharmacokinetics ; Humans ; Prevalence ; Recurrence ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Oil-Fortified Maize Porridge Increases Absorption of Lumefantrine in Children with Uncomplicated Falciparum Malaria.
Autorzy:
Mwebaza N; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institute Huddinge, Stockholm, Sweden.; Department of Pharmacology and Therapeutics, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala, Uganda.
Jerling M; Markus Jerling Consulting AB, Bromma, Sweden.
Gustafsson LL; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institute Huddinge, Stockholm, Sweden.
Silva AV; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institute Huddinge, Stockholm, Sweden.
Pohanka A; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institute Huddinge, Stockholm, Sweden.
Obua C; Department of Pharmacology and Therapeutics, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala, Uganda.
Waako P; Department of Pharmacology and Therapeutics, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala, Uganda.
Beck O; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institute Huddinge, Stockholm, Sweden.
Homann MV; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Unit of Infectious Diseases, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.
Färnert A; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Unit of Infectious Diseases, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.
Hellgren U; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institute, Stockholm, Sweden.
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Źródło:
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2017 May; Vol. 120 (5), pp. 457-465. Date of Electronic Publication: 2017 Feb 22.
Typ publikacji:
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms:
Food-Drug Interactions*
Antimalarials/*administration & dosage
Ethanolamines/*administration & dosage
Fluorenes/*administration & dosage
Malaria, Falciparum/*drug therapy
Administration, Oral ; Animals ; Antimalarials/pharmacokinetics ; Area Under Curve ; Biological Availability ; Child, Preschool ; Ethanolamines/pharmacokinetics ; Female ; Fluorenes/pharmacokinetics ; Humans ; Infant ; Lumefantrine ; Male ; Milk ; Plant Oils/administration & dosage ; Tablets ; Time Factors ; Treatment Outcome ; Uganda ; Zea mays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Therapeutic efficacy of artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria in a high-transmission area in northwest Ethiopia.
Autorzy:
Teklemariam M; Department of Microbial, Cellular and Molecular Biology; College of Natural Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Assefa A; Bacterial, Parasitic and Zoonotic Diseases Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Kassa M; Bacterial, Parasitic and Zoonotic Diseases Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Mohammed H; Bacterial, Parasitic and Zoonotic Diseases Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Mamo H; Department of Microbial, Cellular and Molecular Biology; College of Natural Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
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Źródło:
PloS one [PLoS One] 2017 Apr 26; Vol. 12 (4), pp. e0176004. Date of Electronic Publication: 2017 Apr 26 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials/*therapeutic use
Artemisinins/*therapeutic use
Ethanolamines/*therapeutic use
Fluorenes/*therapeutic use
Malaria, Falciparum/*drug therapy
Adolescent ; Adult ; Antimalarials/adverse effects ; Artemether ; Artemisinins/adverse effects ; Child ; Child, Preschool ; DNA, Protozoan/metabolism ; Drug Combinations ; Ethanolamines/adverse effects ; Ethiopia/epidemiology ; Female ; Fluorenes/adverse effects ; Follow-Up Studies ; Headache/etiology ; Hemoglobins/analysis ; Humans ; Lumefantrine ; Malaria, Falciparum/epidemiology ; Malaria, Falciparum/microbiology ; Malaria, Falciparum/transmission ; Male ; Plasmodium falciparum/genetics ; Plasmodium falciparum/isolation & purification ; Prospective Studies ; Treatment Outcome ; World Health Organization ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Efficacy of artemether-lumefantrine in relation to drug exposure in children with and without severe acute malnutrition: an open comparative intervention study in Mali and Niger.
Autorzy:
Denoeud-Ndam L; Epicentre, Paris, France. .
Dicko A; Malaria Research and Training Center, Faculté de Médecine et d'Odonto-stomatologie et Faculté de Pharmacie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali.
Baudin E; Epicentre, Paris, France.
Guindo O; Epicentre, Maradi, Niger.
Grandesso F; Epicentre, Paris, France.
Diawara H; Malaria Research and Training Center, Faculté de Médecine et d'Odonto-stomatologie et Faculté de Pharmacie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali.
Sissoko S; Malaria Research and Training Center, Faculté de Médecine et d'Odonto-stomatologie et Faculté de Pharmacie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali.
Sanogo K; Malaria Research and Training Center, Faculté de Médecine et d'Odonto-stomatologie et Faculté de Pharmacie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali.
Traoré S; Malaria Research and Training Center, Faculté de Médecine et d'Odonto-stomatologie et Faculté de Pharmacie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali.
Keita S; Malaria Research and Training Center, Faculté de Médecine et d'Odonto-stomatologie et Faculté de Pharmacie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali.
Barry A; Malaria Research and Training Center, Faculté de Médecine et d'Odonto-stomatologie et Faculté de Pharmacie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali.
de Smet M; Medecins Sans Frontieres, Brussels, Belgium.
Lasry E; Medecins Sans Frontieres, New York, NY, USA.
Smit M; Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa.
Wiesner L; Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa.
Barnes KI; Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa.; WorldWide Antimalarial Resistance Network (WWARN), Oxford, UK.
Djimde AA; Malaria Research and Training Center, Faculté de Médecine et d'Odonto-stomatologie et Faculté de Pharmacie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali.
Guerin PJ; WorldWide Antimalarial Resistance Network (WWARN), Oxford, UK.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Oxford University, Oxford, UK.
Grais RF; Epicentre, Paris, France.
Doumbo OK; Malaria Research and Training Center, Faculté de Médecine et d'Odonto-stomatologie et Faculté de Pharmacie, Université des Sciences Techniques et Technologies de Bamako, Bamako, Mali.
Etard JF; Epicentre, Paris, France.; TransVIHMI UMI 233, Institut de Recherche pour le Développement (IRD) - Inserm U 1175 - Montpellier 1 University, Montpellier, France.
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Źródło:
BMC medicine [BMC Med] 2016 Oct 24; Vol. 14 (1), pp. 167. Date of Electronic Publication: 2016 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials/*pharmacokinetics
Artemisinins/*pharmacokinetics
Ethanolamines/*pharmacokinetics
Fluorenes/*pharmacokinetics
Malaria, Falciparum/*drug therapy
Severe Acute Malnutrition/*metabolism
Antimalarials/administration & dosage ; Artemether, Lumefantrine Drug Combination ; Artemisinins/administration & dosage ; Child, Preschool ; Drug Combinations ; Ethanolamines/administration & dosage ; Female ; Fluorenes/administration & dosage ; Humans ; Infant ; Malaria, Falciparum/metabolism ; Male ; Mali ; Niger ; Severe Acute Malnutrition/parasitology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Therapeutic efficacy of artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria from three highly malarious states in India.
Autorzy:
Bharti PK; National Institute for Research in Tribal Health (NIRTH), Jabalpur, Madhya Pradesh, 482003, India.
Shukla MM; National Institute for Research in Tribal Health (NIRTH), Jabalpur, Madhya Pradesh, 482003, India.
Ringwald P; Global Malaria Programme World Health Organization, Geneva, Switzerland.
Krishna S; National Institute for Research in Tribal Health (NIRTH), Jabalpur, Madhya Pradesh, 482003, India.
Singh PP; National Institute for Research in Tribal Health (NIRTH), Jabalpur, Madhya Pradesh, 482003, India.
Yadav A; National Institute for Research in Tribal Health (NIRTH), Jabalpur, Madhya Pradesh, 482003, India.
Mishra S; National Institute for Research in Tribal Health (NIRTH), Jabalpur, Madhya Pradesh, 482003, India.
Gahlot U; Community Health Centre Ranapur, District Jhabua, Madhya Pradesh, India.
Malaiya JP; Community Health Centre Rajendragram, District Anuppur, Madhya Pradesh, India.
Kumar A; Community Health Centre Jaldega, District Simdega, Jharkhand, India.
Prasad S; Community Health Centre Bano, District Simdega, Jharkhand, India.
Baghel P; Community Health Centre Kilepal, District Bastar, Chhattisgarh, India.
Singh M; Satpura Bhawan, Bhopal, Madhya Pradesh, India.
Vadadi J; Indravati Bhawan, Raipur, Chhattisgarh, India.
Singh MP; National Institute of Malaria Research (NIMR) Field Station, Jabalpur, MP, India.
Bustos MD; World Health Organization, Country Office for Thailand, Bangkok, Thailand.
Ortega LI; Global Malaria Programme World Health Organization, Geneva, Switzerland.
Christophel EM; World Health Organization, Regional Office for South-East Asia, New Delhi, India.
Kashyotia SS; National Vector Borne Disease Control Programme (NVBDCP), New Delhi, India.
Sonal GS; National Vector Borne Disease Control Programme (NVBDCP), New Delhi, India.
Singh N; National Institute for Research in Tribal Health (NIRTH), Jabalpur, Madhya Pradesh, 482003, India. .
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Źródło:
Malaria journal [Malar J] 2016 Oct 13; Vol. 15 (1), pp. 498. Date of Electronic Publication: 2016 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials/*therapeutic use
Artemisinins/*therapeutic use
Ethanolamines/*therapeutic use
Fluorenes/*therapeutic use
Malaria, Falciparum/*drug therapy
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antigens, Protozoan/genetics ; Antimalarials/adverse effects ; Artemether, Lumefantrine Drug Combination ; Artemisinins/adverse effects ; Child ; Child, Preschool ; Drug Combinations ; Drug-Related Side Effects and Adverse Reactions ; Ethanolamines/adverse effects ; Fluorenes/adverse effects ; Humans ; India ; Infant ; Merozoite Surface Protein 1/genetics ; Middle Aged ; Plasmodium falciparum/classification ; Plasmodium falciparum/genetics ; Plasmodium falciparum/isolation & purification ; Prospective Studies ; Protozoan Proteins/genetics ; Sequence Analysis, DNA ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Formulation design, in vitro characterizations and anti-malarial investigations of artemether and lumefantrine-entrapped solid lipid microparticles.
Autorzy:
Agbo C; a Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences , University of Nigeria , Nsukka , Enugu State , Nigeria ;
Umeyor C; b Nanomedicines and Drug Delivery Research Group, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences , Nnamdi Azikiwe University , Awka , Anambra State , Nigeria ;
Kenechukwu F; a Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences , University of Nigeria , Nsukka , Enugu State , Nigeria ;
Ogbonna J; a Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences , University of Nigeria , Nsukka , Enugu State , Nigeria ;
Chime S; c Department of Pharmaceutical Technology and Industrial Pharmacy, Faculty of Pharmaceutical Sciences , University of Nigeria , Nsukka , Enugu State , Nigeria.
Lovelyn C; a Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences , University of Nigeria , Nsukka , Enugu State , Nigeria ;
Agubata O; c Department of Pharmaceutical Technology and Industrial Pharmacy, Faculty of Pharmaceutical Sciences , University of Nigeria , Nsukka , Enugu State , Nigeria.
Ofokansi K; a Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences , University of Nigeria , Nsukka , Enugu State , Nigeria ;
Attama A; a Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences , University of Nigeria , Nsukka , Enugu State , Nigeria ;
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Źródło:
Drug development and industrial pharmacy [Drug Dev Ind Pharm] 2016 Oct; Vol. 42 (10), pp. 1708-21. Date of Electronic Publication: 2016 Apr 19.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials/*administration & dosage
Artemisinins/*administration & dosage
Drug Delivery Systems/*methods
Ethanolamines/*administration & dosage
Fluorenes/*administration & dosage
Lipids/*chemistry
Administration, Oral ; Animals ; Antimalarials/chemistry ; Artemether ; Artemisinins/chemistry ; Biological Availability ; Drug Design ; Ethanolamines/chemistry ; Fluorenes/chemistry ; Lumefantrine ; Mice ; Microspheres ; Particle Size ; Solubility
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Selection of N86F184D1246 haplotype of Pfmrd1 gene by artemether-lumefantrine drug pressure on Plasmodium falciparum populations in Senegal.
Autorzy:
Mbaye A; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal. .
Dieye B; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Ndiaye YD; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Bei AK; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA.
Muna A; Malaria Research Centre, Serrekunda, Gambia.
Deme AB; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Yade MS; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Diongue K; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Gaye A; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Ndiaye IM; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Ndiaye T; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Sy M; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Diallo MA; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Badiane AS; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Ndiaye M; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Seck MC; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Sy N; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.
Koita O; University of Bamako, Bamako, Mali.
Krogstad DJ; Tulane University, New Orleans, LA, USA.
Nwakanma D; Malaria Research Centre, Serrekunda, Gambia.
Ndiaye D; Laboratory of Parasitology/Mycology HALD, Cheikh Anta Diop University of Dakar, PO Box 5005, Dakar, Senegal.; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, USA.
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Źródło:
Malaria journal [Malar J] 2016 Aug 25; Vol. 15 (1), pp. 433. Date of Electronic Publication: 2016 Aug 25.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Frequency*
Haplotypes*
Selection, Genetic*
Antimalarials/*pharmacology
Artemisinins/*pharmacology
Ethanolamines/*pharmacology
Fluorenes/*pharmacology
Multidrug Resistance-Associated Proteins/*genetics
Plasmodium falciparum/*drug effects
Adolescent ; Antimalarials/therapeutic use ; Artemether, Lumefantrine Drug Combination ; Artemisinins/therapeutic use ; Child ; Child, Preschool ; Drug Combinations ; Ethanolamines/therapeutic use ; Female ; Fluorenes/therapeutic use ; Genetics, Population ; Genotyping Techniques ; Humans ; Malaria, Falciparum/parasitology ; Male ; Plasmodium falciparum/classification ; Plasmodium falciparum/genetics ; Senegal ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Development of a pharmacovigilance safety monitoring tool for the rollout of single low-dose primaquine and artemether-lumefantrine to treat Plasmodium falciparum infections in Swaziland: a pilot study.
Autorzy:
Poirot E; Global Health Group, University of California San Francisco, San Francisco, CA, USA. .; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA. .
Soble A; Clinton Health Access Initiative, Mbabane, Swaziland.
Ntshalintshali N; Clinton Health Access Initiative, Mbabane, Swaziland.
Mwandemele A; University of Namibia, Windhoek, Namibia.
Mkhonta N; National Malaria Control Programme, Manzini, Swaziland.
Malambe C; National Malaria Control Programme, Manzini, Swaziland.
Vilakati S; National Malaria Control Programme, Manzini, Swaziland.
Pan S; Clinton Health Access Initiative, Mbabane, Swaziland.
Darteh S; International Center for AIDS Care and Treatment Programs, Mbabane, Swaziland.
Maphalala G; Swaziland Health Laboratory Services, Mbabane, Swaziland.
Brown J; Global Health Group, University of California San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Hwang J; Global Health Group, University of California San Francisco, San Francisco, CA, USA.; President's Malaria Initiative, Malaria Branch, U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Pace C; Liverpool School of Tropical Medicine, Liverpool, UK.
Stergachis A; Departments of Pharmacy and Global Health, Schools of Pharmacy and Public Health, University of Washington, Seattle, USA.
Vittinghoff E; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Kunene S; National Malaria Control Programme, Manzini, Swaziland.
Gosling R; Global Health Group, University of California San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
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Źródło:
Malaria journal [Malar J] 2016 Jul 22; Vol. 15 (1), pp. 384. Date of Electronic Publication: 2016 Jul 22.
Typ publikacji:
Journal Article
MeSH Terms:
Pharmacovigilance*
Antimalarials/*adverse effects
Artemisinins/*adverse effects
Ethanolamines/*adverse effects
Fluorenes/*adverse effects
Malaria, Falciparum/*drug therapy
Primaquine/*adverse effects
Product Surveillance, Postmarketing/*methods
Adolescent ; Adult ; Aged ; Antimalarials/administration & dosage ; Artemether, Lumefantrine Drug Combination ; Artemisinins/administration & dosage ; Child ; Child, Preschool ; Drug Combinations ; Drug-Related Side Effects and Adverse Reactions/epidemiology ; Drug-Related Side Effects and Adverse Reactions/pathology ; Eswatini ; Ethanolamines/administration & dosage ; Female ; Fluorenes/administration & dosage ; Humans ; Infant ; Male ; Middle Aged ; Pilot Projects ; Primaquine/administration & dosage ; Prospective Studies ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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