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    Wyświetlanie 1-5 z 5
    Tytuł:
    Brain-derived neurotrophic factor in cerebrospinal fluid and plasma is not a biomarker for Huntington's disease.
    Autorzy:
    Ou ZA; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
    Byrne LM; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
    Rodrigues FB; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
    Tortelli R; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
    Johnson EB; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
    Foiani MS; UK Dementia Research Institute at UCL, London, WC1E 6BT, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, WC1N 3BG, UK.
    Arridge M; Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, WC1N 3BG, UK.
    De Vita E; Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, WC1N 3BG, UK.; Department of Biomedical Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, SE1 7EH, UK.
    Scahill RI; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
    Heslegrave A; UK Dementia Research Institute at UCL, London, WC1E 6BT, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, WC1N 3BG, UK.
    Zetterberg H; UK Dementia Research Institute at UCL, London, WC1E 6BT, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, WC1N 3BG, UK.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 431 80, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, 431 80, Mölndal, Sweden.
    Wild EJ; UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK. .
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    Źródło:
    Scientific reports [Sci Rep] 2021 Feb 10; Vol. 11 (1), pp. 3481. Date of Electronic Publication: 2021 Feb 10.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Brain-Derived Neurotrophic Factor/*blood
    Brain-Derived Neurotrophic Factor/*cerebrospinal fluid
    Huntington Disease/*blood
    Huntington Disease/*cerebrospinal fluid
    Adult ; Biomarkers/blood ; Biomarkers/cerebrospinal fluid ; Cohort Studies ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunoassay ; Male ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    CSF synaptic protein concentrations are raised in those with atypical Alzheimer's disease but not frontotemporal dementia.
    Autorzy:
    Clarke MTM; Dementia Research Centre, Department of Neurodegenerative Disease, University College London, Queen Square Institute of Neurology, London, WC1N 3BG, UK.
    Brinkmalm A; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
    Foiani MS; UK Dementia Research Institute at UCL, London, UK.; Department of Neurodegenerative Disease, University College London, London, UK.
    Woollacott IOC; Dementia Research Centre, Department of Neurodegenerative Disease, University College London, Queen Square Institute of Neurology, London, WC1N 3BG, UK.
    Heller C; UK Dementia Research Institute at UCL, London, UK.; Department of Neurodegenerative Disease, University College London, London, UK.
    Heslegrave A; UK Dementia Research Institute at UCL, London, UK.; Department of Neurodegenerative Disease, University College London, London, UK.
    Keshavan A; Dementia Research Centre, Department of Neurodegenerative Disease, University College London, Queen Square Institute of Neurology, London, WC1N 3BG, UK.
    Fox NC; Dementia Research Centre, Department of Neurodegenerative Disease, University College London, Queen Square Institute of Neurology, London, WC1N 3BG, UK.
    Schott JM; Dementia Research Centre, Department of Neurodegenerative Disease, University College London, Queen Square Institute of Neurology, London, WC1N 3BG, UK.
    Warren JD; Dementia Research Centre, Department of Neurodegenerative Disease, University College London, Queen Square Institute of Neurology, London, WC1N 3BG, UK.
    Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
    Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; UK Dementia Research Institute at UCL, London, UK.; Department of Neurodegenerative Disease, University College London, London, UK.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
    Rohrer JD; Dementia Research Centre, Department of Neurodegenerative Disease, University College London, Queen Square Institute of Neurology, London, WC1N 3BG, UK. .
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    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2019 Dec 17; Vol. 11 (1), pp. 105. Date of Electronic Publication: 2019 Dec 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease/*cerebrospinal fluid
    Frontotemporal Dementia/*cerebrospinal fluid
    Neurogranin/*cerebrospinal fluid
    Synaptosomal-Associated Protein 25/*cerebrospinal fluid
    Synaptotagmin I/*cerebrospinal fluid
    Aged ; Amyloid beta-Peptides/cerebrospinal fluid ; Biomarkers/cerebrospinal fluid ; Female ; Humans ; Male ; Middle Aged ; Peptide Fragments/cerebrospinal fluid ; tau Proteins/cerebrospinal fluid
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer's disease.
    Autorzy:
    Sánchez-Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Villarroel, 170, 08036, Barcelona, Spain. .
    Heslegrave A; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.
    Foiani MS; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.
    Bosch B; Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Villarroel, 170, 08036, Barcelona, Spain.
    Antonell A; Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Villarroel, 170, 08036, Barcelona, Spain.
    Balasa M; Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Villarroel, 170, 08036, Barcelona, Spain.
    Lladó A; Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Villarroel, 170, 08036, Barcelona, Spain.
    Zetterberg H; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
    Fox NC; UK Dementia Research Institute at UCL, London, UK.; Dementia Research Centre, University College of London, Institute of Neurology, London, UK.
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    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2018 Nov 03; Vol. 10 (1), pp. 113. Date of Electronic Publication: 2018 Nov 03.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease/*diagnosis
    Neurofilament Proteins/*blood
    Adult ; Alzheimer Disease/blood ; Alzheimer Disease/cerebrospinal fluid ; Alzheimer Disease/genetics ; Biomarkers/blood ; Biomarkers/cerebrospinal fluid ; Cross-Sectional Studies ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Mutation ; Neurofilament Proteins/cerebrospinal fluid ; Severity of Illness Index
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup.
    Autorzy:
    Woollacott IOC; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
    Nicholas JM; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
    Heslegrave A; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute, London, UK.
    Heller C; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute, London, UK.
    Foiani MS; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute, London, UK.
    Dick KM; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
    Russell LL; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
    Paterson RW; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
    Keshavan A; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
    Fox NC; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.; UK Dementia Research Institute, London, UK.
    Warren JD; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
    Schott JM; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
    Zetterberg H; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute, London, UK.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
    Rohrer JD; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. .
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    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2018 Aug 16; Vol. 10 (1), pp. 79. Date of Electronic Publication: 2018 Aug 16.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Frontotemporal Dementia*/cerebrospinal fluid
    Frontotemporal Dementia*/genetics
    Frontotemporal Dementia*/pathology
    Membrane Glycoproteins/*cerebrospinal fluid
    Age Factors ; Aged ; Amyloid beta-Peptides/cerebrospinal fluid ; Aphasia, Primary Progressive/genetics ; C9orf72 Protein/genetics ; Cohort Studies ; Female ; Gene Expression Regulation/genetics ; Humans ; Male ; Middle Aged ; Peptide Fragments/cerebrospinal fluid ; Phosphorylation ; Receptors, Immunologic ; Statistics, Nonparametric ; tau Proteins/cerebrospinal fluid ; tau Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cerebrospinal fluid in the differential diagnosis of Alzheimer's disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic.
    Autorzy:
    Paterson RW; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.
    Slattery CF; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.
    Poole T; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.; Department of Medical Statistics, London School of Hygiene & Tropical Medicine, London, UK.
    Nicholas JM; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.; Department of Medical Statistics, London School of Hygiene & Tropical Medicine, London, UK.
    Magdalinou NK; Lila Weston Institute, UCL Institute of Neurology, London, UK.
    Toombs J; Department of Molecular Neuroscience, Institute of Neurology, UCL, London, UK.
    Chapman MD; Department of Neuroimmunology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
    Lunn MP; Department of Neuroimmunology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
    Heslegrave AJ; Department of Molecular Neuroscience, Institute of Neurology, UCL, London, UK.
    Foiani MS; Department of Molecular Neuroscience, Institute of Neurology, UCL, London, UK.
    Weston PSJ; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.
    Keshavan A; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.
    Rohrer JD; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.
    Rossor MN; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.
    Warren JD; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.
    Mummery CJ; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.
    Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
    Fox NC; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK.
    Zetterberg H; Department of Molecular Neuroscience, Institute of Neurology, UCL, London, UK.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
    Schott JM; Dementia Research Centre, UCL Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG, UK. .
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    Źródło:
    Alzheimer's research & therapy [Alzheimers Res Ther] 2018 Mar 20; Vol. 10 (1), pp. 32. Date of Electronic Publication: 2018 Mar 20.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Diagnosis, Differential*
    Alzheimer Disease/*cerebrospinal fluid
    Alzheimer Disease/*diagnosis
    Biomarkers/*cerebrospinal fluid
    Aged ; Amyloid beta-Peptides/cerebrospinal fluid ; Cohort Studies ; Female ; Humans ; Male ; Middle Aged ; Phosphorylation ; ROC Curve ; Sensitivity and Specificity ; tau Proteins/cerebrospinal fluid
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-5 z 5

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