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Tytuł :
Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge.
Autorzy :
Hansen SG; Oregon Health & Science University, Vaccine & Gene Therapy Institute, Beaverton, OR, United States of America.; Oregon Health & Science University, Oregon National Primate Research Center, Beaverton, OR, United States of America.
Womack J; Oregon Health & Science University, Vaccine & Gene Therapy Institute, Beaverton, OR, United States of America.
Scholz I; Oregon Health & Science University, Vaccine & Gene Therapy Institute, Beaverton, OR, United States of America.
Renner A; US Military Malaria Vaccine Program, Naval Medical Research Center, Silver Spring, MD, United States of America.
Edgel KA; US Military Malaria Vaccine Program, Naval Medical Research Center, Silver Spring, MD, United States of America.
Xu G; Oregon Health & Science University, Vaccine & Gene Therapy Institute, Beaverton, OR, United States of America.
Ford JC; Oregon Health & Science University, Vaccine & Gene Therapy Institute, Beaverton, OR, United States of America.
Grey M; Oregon Health & Science University, Vaccine & Gene Therapy Institute, Beaverton, OR, United States of America.
St Laurent B; National Institutes of Health, Laboratory of Malaria and Vector Research, Malaria Pathogenesis and Human Immunity Unit, Rockville, MD, United States of America.
Turner JM; Oregon Health & Science University, Oregon National Primate Research Center, Beaverton, OR, United States of America.
Planer S; Oregon Health & Science University, Oregon National Primate Research Center, Beaverton, OR, United States of America.
Legasse AW; Oregon Health & Science University, Oregon National Primate Research Center, Beaverton, OR, United States of America.
Richie TL; US Military Malaria Vaccine Program, Naval Medical Research Center, Silver Spring, MD, United States of America.
Aguiar JC; US Military Malaria Vaccine Program, Naval Medical Research Center, Silver Spring, MD, United States of America.
Axthelm MK; Oregon Health & Science University, Vaccine & Gene Therapy Institute, Beaverton, OR, United States of America.; Oregon Health & Science University, Oregon National Primate Research Center, Beaverton, OR, United States of America.
Villasante ED; US Military Malaria Vaccine Program, Naval Medical Research Center, Silver Spring, MD, United States of America.
Weiss W; US Military Malaria Vaccine Program, Naval Medical Research Center, Silver Spring, MD, United States of America.
Edlefsen PT; Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
Picker LJ; Oregon Health & Science University, Vaccine & Gene Therapy Institute, Beaverton, OR, United States of America.; Oregon Health & Science University, Oregon National Primate Research Center, Beaverton, OR, United States of America.
Früh K; Oregon Health & Science University, Vaccine & Gene Therapy Institute, Beaverton, OR, United States of America.; Oregon Health & Science University, Oregon National Primate Research Center, Beaverton, OR, United States of America.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2019 Jan 23; Vol. 14 (1), pp. e0210252. Date of Electronic Publication: 2019 Jan 23 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antigens, Protozoan/*immunology
Cytomegalovirus/*genetics
Malaria/*immunology
Malaria Vaccines/*immunology
Parasitemia/*immunology
Plasmodium knowlesi/*immunology
Sporozoites/*immunology
Animals ; Anopheles/immunology ; Anopheles/parasitology ; Female ; Genetic Vectors/administration & dosage ; Immunologic Memory ; Liver/immunology ; Liver/parasitology ; Macaca mulatta ; Malaria/blood ; Malaria/parasitology ; Malaria/prevention & control ; Male ; Parasitemia/blood ; Parasitemia/parasitology ; Parasitemia/prevention & control ; Plasmodium knowlesi/genetics ; Protozoan Proteins/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/parasitology
Czasopismo naukowe
Tytuł :
Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.
Autorzy :
Okoye AA; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Hansen SG; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Vaidya M; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Fukazawa Y; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Park H; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Duell DM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Lum R; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Hughes CM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Ventura AB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Ainslie E; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Ford JC; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Morrow D; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Gilbride RM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Legasse AW; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Hesselgesser J; Gilead Sciences, Inc., Foster City, CA, USA.
Geleziunas R; Gilead Sciences, Inc., Foster City, CA, USA.
Li Y; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Oswald K; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Shoemaker R; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Fast R; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Bosche WJ; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Borate BR; Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Edlefsen PT; Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Axthelm MK; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Picker LJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA. .
Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA. .
Pokaż więcej
Źródło :
Nature medicine [Nat Med] 2018 Sep; Vol. 24 (9), pp. 1430-1440. Date of Electronic Publication: 2018 Aug 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Retroviral Agents/*therapeutic use
Simian Acquired Immunodeficiency Syndrome/*drug therapy
Simian Acquired Immunodeficiency Syndrome/*virology
Simian Immunodeficiency Virus/*physiology
Adoptive Transfer ; Animals ; Anti-Retroviral Agents/pharmacology ; Drug Therapy, Combination ; Kinetics ; Macaca mulatta ; Necrosis ; Simian Immunodeficiency Virus/drug effects ; Vaccination ; Viral Vaccines/immunology ; Viremia/drug therapy ; Virus Replication
Czasopismo naukowe
Tytuł :
Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine.
Autorzy :
Hansen SG; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Zak DE; Center for Infectious Disease Research, Seattle, Washington, USA.
Xu G; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Ford JC; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Marshall EE; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Malouli D; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Gilbride RM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Hughes CM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Ventura AB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Ainslie E; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Randall KT; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Selseth AN; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Rundstrom P; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Herlache L; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Lewis MS; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Park H; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Planer SL; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Turner JM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Fischer M; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Armstrong C; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Zweig RC; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Valvo J; Center for Infectious Disease Research, Seattle, Washington, USA.
Braun JM; Center for Infectious Disease Research, Seattle, Washington, USA.
Shankar S; Center for Infectious Disease Research, Seattle, Washington, USA.
Lu L; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA.
Sylwester AW; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Legasse AW; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Messerle M; Department of Virology, Hannover Medical School, Hannover, Germany.
Jarvis MA; School of Biomedical and Healthcare Sciences, University of Plymouth, Devon, UK.
Amon LM; Center for Infectious Disease Research, Seattle, Washington, USA.
Aderem A; Center for Infectious Disease Research, Seattle, Washington, USA.
Alter G; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA.
Laddy DJ; Aeras, Rockville, Maryland, USA.
Stone M; Aeras, Rockville, Maryland, USA.
Bonavia A; Aeras, Rockville, Maryland, USA.
Evans TG; Aeras, Rockville, Maryland, USA.
Axthelm MK; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Früh K; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Edlefsen PT; Statistical Center for HIV-AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Picker LJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health and Science University (OHSU), Beaverton, Oregon, USA.
Pokaż więcej
Źródło :
Nature medicine [Nat Med] 2018 Feb; Vol. 24 (2), pp. 130-143. Date of Electronic Publication: 2018 Jan 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Mycobacterium tuberculosis/*immunology
Tuberculosis/*immunology
Animals ; BCG Vaccine/immunology ; Cytomegalovirus/immunology ; Macaca mulatta/immunology
Czasopismo naukowe
Tytuł :
Addendum: Immune clearance of highly pathogenic SIV infection.
Autorzy :
Hansen SG
Piatak M
Ventura AB
Hughes CM
Gilbride RM
Ford JC
Oswald K
Shoemaker R
Li Y
Lewis MS
Gilliam AN
Xu G
Whizin N
Burwitz BJ
Planer SL
Turner JM
Legasse AW
Axthelm MK
Nelson JA
Früh K
Sacha JB
Estes JD
Keele BF
Edlefsen PT
Lifson JD
Picker LJ
Pokaż więcej
Źródło :
Nature [Nature] 2017 Jul 06; Vol. 547 (7661), pp. 123-124. Date of Electronic Publication: 2017 Jun 21.
Typ publikacji :
Journal Article; Published Erratum
Czasopismo naukowe
Tytuł :
Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E.
Autorzy :
Hansen SG; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Wu HL; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Burwitz BJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Hughes CM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Hammond KB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Ventura AB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Reed JS; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Gilbride RM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Ainslie E; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Morrow DW; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Ford JC; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Selseth AN; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Pathak R; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Malouli D; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Legasse AW; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Axthelm MK; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Nelson JA; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Gillespie GM; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
Walters LC; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
Brackenridge S; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
Sharpe HR; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
López CA; Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Früh K; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Korber BT; Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. The New Mexico Consortium, Los Alamos, NM 87545, USA.
McMichael AJ; Nuffield Department of Medicine, University of Oxford, Oxford OX37FZ, UK.
Gnanakaran S; Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Sacha JB; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Picker LJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Pokaż więcej
Źródło :
Science (New York, N.Y.) [Science] 2016 Feb 12; Vol. 351 (6274), pp. 714-20. Date of Electronic Publication: 2016 Jan 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
CD8-Positive T-Lymphocytes/*immunology
Cytomegalovirus/*immunology
Epitopes, T-Lymphocyte/*immunology
Histocompatibility Antigens Class I/*immunology
Simian Immunodeficiency Virus/*immunology
Animals ; Antigen Presentation ; Antigenic Variation ; Cytomegalovirus/genetics ; Epitopes, T-Lymphocyte/chemistry ; Genetic Vectors/genetics ; Genetic Vectors/immunology ; Histocompatibility Antigens Class I/chemistry ; Host-Pathogen Interactions/immunology ; Immune Evasion ; Killer Cells, Natural/immunology ; Macaca mulatta ; Protein Structure, Secondary ; Vaccination
Czasopismo naukowe
Tytuł :
Immune clearance of highly pathogenic SIV infection.
Autorzy :
Hansen SG; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon 97006, USA.
Piatak M Jr
Ventura AB
Hughes CM
Gilbride RM
Ford JC
Oswald K
Shoemaker R
Li Y
Lewis MS
Gilliam AN
Xu G
Whizin N
Burwitz BJ
Planer SL
Turner JM
Legasse AW
Axthelm MK
Nelson JA
Früh K
Sacha JB
Estes JD
Keele BF
Edlefsen PT
Lifson JD
Picker LJ
Pokaż więcej
Źródło :
Nature [Nature] 2013 Oct 03; Vol. 502 (7469), pp. 100-4. Date of Electronic Publication: 2013 Sep 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
SAIDS Vaccines/*immunology
Simian Acquired Immunodeficiency Syndrome/*prevention & control
Simian Immunodeficiency Virus/*immunology
Animals ; Cytomegalovirus/genetics ; Cytomegalovirus/immunology ; Female ; Macaca mulatta ; Male ; Molecular Sequence Data ; Simian Acquired Immunodeficiency Syndrome/virology ; Time Factors ; Vaccines, Attenuated/immunology ; Viral Load ; Virus Replication/physiology
Czasopismo naukowe

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