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Tytuł :
Mice Lacking Connective Tissue Growth Factor in the Forebrain Exhibit Delayed Seizure Response, Reduced C-Fos Expression and Different Microglial Phenotype Following Acute PTZ Injection.
Autorzy :
Siow PF; Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei 10048, Taiwan.; Department of Neurology, Chang Gung Memorial Hospital, Keelung 20401, Taiwan.
Tsao CY; Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei 10048, Taiwan.
Chang HC; Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei 10048, Taiwan.
Chen CY; Department of Neurology, Chang Gung Memorial Hospital, Keelung 20401, Taiwan.
Yu IS; Laboratory Animal Center, College of Medicine, National Taiwan University, Taipei 10048, Taiwan.
Lee KY; Department of Neurology, Chang Gung Memorial Hospital, Keelung 20401, Taiwan.; College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Lee LJ; Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei 10048, Taiwan.; Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei 10048, Taiwan.; Neurobiology and Cognitive Science Center, National Taiwan University, Taipei 10617, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jul 12; Vol. 21 (14). Date of Electronic Publication: 2020 Jul 12.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, fos*
Astrocytes/*physiology
Connective Tissue Growth Factor/*deficiency
Microglia/*physiology
Prosencephalon/*metabolism
Seizures/*physiopathology
Animals ; Astrocytes/drug effects ; Cell Count ; Claustrum/drug effects ; Claustrum/metabolism ; Connective Tissue Growth Factor/physiology ; Convulsants/toxicity ; Gene Expression Regulation/drug effects ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microglia/drug effects ; Nerve Tissue Proteins/biosynthesis ; Nerve Tissue Proteins/genetics ; Pentylenetetrazole/toxicity ; Prosencephalon/drug effects ; Proto-Oncogene Proteins c-fos/biosynthesis ; Proto-Oncogene Proteins c-fos/genetics ; Seizures/chemically induced ; Seizures/genetics ; Seizures/pathology
Czasopismo naukowe
Tytuł :
Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers.
Autorzy :
Bejjani F; IGMM, Univ Montpellier, CNRS, Montpellier, France.; PRASE, DSST, ER045, Lebanese University, Beirut, Lebanon.
Tolza C; IGMM, Univ Montpellier, CNRS, Montpellier, France.
Boulanger M; IGMM, Univ Montpellier, CNRS, Montpellier, France.
Downes D; Medical Research Council, Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford University, Oxford, UK.
Romero R; IMAG, Univ Montpellier, CNRS, Montpellier, France.; LIRMM, Univ Montpellier, CNRS, Montpellier, France.
Maqbool MA; IGMM, Univ Montpellier, CNRS, Montpellier, France.
Zine El Aabidine A; IGMM, Univ Montpellier, CNRS, Montpellier, France.
Andrau JC; IGMM, Univ Montpellier, CNRS, Montpellier, France.
Lebre S; IMAG, Univ Montpellier, CNRS, Montpellier, France.
Brehelin L; LIRMM, Univ Montpellier, CNRS, Montpellier, France.
Parrinello H; Montpellier GenomiX, MGX, BioCampus Montpellier, CNRS, INSERM, Univ. Montpellier, F-34094 Montpellier, France.
Rohmer M; Montpellier GenomiX, MGX, BioCampus Montpellier, CNRS, INSERM, Univ. Montpellier, F-34094 Montpellier, France.
Kaoma T; Computational Biomedecine, Quantitative Biology Unit, Luxembourg Institute of Health, Strassen, Luxembourg.
Vallar L; Proteome and Genome Research Unit, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.
Hughes JR; Medical Research Council, Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford University, Oxford, UK.
Zibara K; PRASE, DSST, ER045, Lebanese University, Beirut, Lebanon.; Biology Department, Faculty of Sciences-I, Lebanese University, Beirut, Lebanon.
Lecellier CH; IGMM, Univ Montpellier, CNRS, Montpellier, France.; LIRMM, Univ Montpellier, CNRS, Montpellier, France.
Piechaczyk M; IGMM, Univ Montpellier, CNRS, Montpellier, France.
Jariel-Encontre I; IGMM, Univ Montpellier, CNRS, Montpellier, France.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Mar 18; Vol. 49 (5), pp. 2488-2508.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enhancer Elements, Genetic*
Gene Expression Regulation, Neoplastic*
Proto-Oncogene Proteins c-fos/*metabolism
Triple Negative Breast Neoplasms/*genetics
Binding Sites ; Cell Line, Tumor ; Chromatin/chemistry ; Chromatin/metabolism ; Epigenesis, Genetic ; Fos-Related Antigen-2/metabolism ; Humans ; Nucleotide Motifs ; Promoter Regions, Genetic ; Proto-Oncogene Proteins c-fos/physiology ; Transcription Factor AP-1/metabolism ; Triple Negative Breast Neoplasms/metabolism ; p300-CBP Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
FOS Rearrangement and Expression in Cementoblastoma.
Autorzy :
Lam SW; Departments of Pathology.
Cleven AHG; Departments of Pathology.
Briaire-de Bruijn IH; Departments of Pathology.
Schreuder WH; Department of Oral and Maxillofacial Surgery/Head and Neck Surgery, Amsterdam University Medical Center/Antoni van Leeuwenhoek Hospital.
Kroon HM; Radiology.
Savci-Heijink DC; Department of Pathology, Academic Medical Center, Amsterdam.
Suurmeijer AJH; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Szuhai K; Cell and Chemical Biology, Leiden University Medical Center, Leiden.
Bovée JVMG; Departments of Pathology.
Baumhoer D; Bone Tumour Reference Centre, Institute of Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2021 May 01; Vol. 45 (5), pp. 690-693.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/genetics
Bone Neoplasms*/chemistry
Bone Neoplasms*/genetics
Bone Neoplasms*/pathology
Dental Cementum*/chemistry
Dental Cementum*/pathology
Gene Rearrangement*
Odontogenic Tumors*/chemistry
Odontogenic Tumors*/genetics
Odontogenic Tumors*/pathology
Osteoblastoma*/chemistry
Osteoblastoma*/genetics
Osteoblastoma*/pathology
Proto-Oncogene Proteins c-fos*/analysis
Proto-Oncogene Proteins c-fos*/genetics
Tooth Root*/chemistry
Tooth Root*/pathology
Adolescent ; Adult ; Child ; Female ; Humans ; Immunohistochemistry ; In Situ Hybridization, Fluorescence ; Male ; Middle Aged ; Netherlands ; Switzerland ; Young Adult
Czasopismo naukowe
Tytuł :
The super-cooling compound icilin stimulates c-Fos and Egr-1 expression and activity involving TRPM8 channel activation, Ca ion influx and activation of the ternary complex factor Elk-1.
Autorzy :
Ulrich M; Department of Medical Biochemistry and Molecular Biology, Germany.
Wissenbach U; Experimental and Clinical Pharmacology, Saarland University Medical Faculty, D-66421 Homburg, Germany.
Thiel G; Department of Medical Biochemistry and Molecular Biology, Germany. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2020 Jul; Vol. 177, pp. 113936. Date of Electronic Publication: 2020 Mar 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, fos*
Calcium/*metabolism
Early Growth Response Protein 1/*metabolism
Ions/*metabolism
Proto-Oncogene Proteins c-fos/*metabolism
Pyrimidinones/*pharmacology
Signal Transduction/*drug effects
TRPM Cation Channels/*metabolism
ets-Domain Protein Elk-1/*metabolism
Calcium Channels/metabolism ; Early Growth Response Protein 1/genetics ; Gene Expression Regulation/drug effects ; Gene Transfer Techniques ; HEK293 Cells ; Humans ; Promoter Regions, Genetic ; Transcription, Genetic/drug effects ; Transcriptional Activation/drug effects ; ets-Domain Protein Elk-1/genetics
Czasopismo naukowe
Tytuł :
The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis.
Autorzy :
Seidenberg J; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, 8952 Schlieren, Switzerland.
Stellato M; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, 8952 Schlieren, Switzerland.
Hukara A; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, 8952 Schlieren, Switzerland.
Ludewig B; Institute of Immunobiology, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland.; Institute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland.
Klingel K; Cardiopathology, Institute for Pathology and Neuropathology, University Hospital Tubingen, D-72076 Tubingen, Germany.
Distler O; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, 8952 Schlieren, Switzerland.
Błyszczuk P; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, 8952 Schlieren, Switzerland.; Department of Clinical Immunology, Jagiellonian University Medical College, 30-663 Krakow, Poland.
Kania G; Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, 8952 Schlieren, Switzerland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 13; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Fibroblasts/*metabolism
Fos-Related Antigen-2/*metabolism
Heart Failure/*metabolism
Myocardium/*metabolism
Transcription Factor AP-1/*metabolism
Aged ; Animals ; Female ; Fibroblasts/pathology ; Fibrosis ; Fos-Related Antigen-2/genetics ; Heart Failure/genetics ; Heart Failure/pathology ; Humans ; Male ; Mice ; Mice, Transgenic ; Middle Aged ; Myocardium/pathology ; Transcription Factor AP-1/genetics
Czasopismo naukowe
Tytuł :
Temporal changes in Egr-1 and c-fos expression in rat models of myocardial ischemia.
Autorzy :
Zhai LQ; Department of Pathology, Shanxi Provincial People's Hospital, Taiyuan, China.
Guo XJ; Department of Pathology, School of Forensic Medicine, Shanxi Medical University, Taiyuan, China.
Li Z; Department of Pathology, School of Forensic Medicine, Shanxi Medical University, Taiyuan, China.
Sun RF; Department of Pathology, School of Forensic Medicine, Shanxi Medical University, Taiyuan, China.
Jin QQ; Department of Pathology, School of Forensic Medicine, Shanxi Medical University, Taiyuan, China.
Liu MZ; Department of Pathology, School of Forensic Medicine, Shanxi Medical University, Taiyuan, China.
Guo HL; Department of Pathology, School of Forensic Medicine, Shanxi Medical University, Taiyuan, China.
Gao CR; Department of Pathology, School of Forensic Medicine, Shanxi Medical University, Taiyuan, China. .
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Źródło :
Annals of palliative medicine [Ann Palliat Med] 2021 Feb; Vol. 10 (2), pp. 1411-1420. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article
MeSH Terms :
Myocardial Ischemia*
Proto-Oncogene Proteins c-fos*/genetics
Animals ; Myocardium ; RNA, Messenger/genetics ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Elevated c-fos expression is correlated with phenotypic switching of human vascular smooth muscle cells derived from lower limb venous varicosities.
Autorzy :
Guo Z; Department of Vascular Surgery Fudan University, Shanghai, People's Republic of China.
Luo C; Department of Cardiac Surgery, Fudan University, Shanghai, People's Republic of China.
Zhu T; Department of Vascular Surgery Fudan University, Shanghai, People's Republic of China.
Li L; Zhongshan Hospital and Department of Vascular Surgery, Huadong Hospital, Fudan University, Shanghai, People's Republic of China.
Zhang W; Zhongshan Hospital and Department of Vascular Surgery, Huadong Hospital, Fudan University, Shanghai, People's Republic of China. Electronic address: .
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Źródło :
Journal of vascular surgery. Venous and lymphatic disorders [J Vasc Surg Venous Lymphat Disord] 2021 Jan; Vol. 9 (1), pp. 242-251. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
Lower Extremity/*blood supply
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Proto-Oncogene Proteins c-fos/*metabolism
Varicose Veins/*metabolism
Actins/genetics ; Actins/metabolism ; Aged ; Case-Control Studies ; Cell Movement ; Cell Proliferation ; Cells, Cultured ; Female ; Humans ; Male ; Middle Aged ; Muscle, Smooth, Vascular/pathology ; Muscle, Smooth, Vascular/surgery ; Myocytes, Smooth Muscle/pathology ; Osteopontin/genetics ; Osteopontin/metabolism ; Phenotype ; Proto-Oncogene Proteins c-fos/genetics ; Signal Transduction ; Up-Regulation ; Varicose Veins/genetics ; Varicose Veins/pathology ; Varicose Veins/surgery ; Veins/metabolism ; Veins/pathology ; Veins/surgery
Czasopismo naukowe
Tytuł :
Post-weaning social isolation increases ΔFosB/FosB protein expression in sex-specific patterns in the prelimbic/infralimbic cortex and hippocampus in mice.
Autorzy :
Noback M; Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, USA.
Zhang G; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, USA.
White N; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, USA.
Barrow JC; Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, USA.
Carr GV; Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA; Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, USA. Electronic address: .
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Źródło :
Neuroscience letters [Neurosci Lett] 2021 Jan 01; Vol. 740, pp. 135423. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Weaning*
Cerebral Cortex/*metabolism
Hippocampus/*metabolism
Limbic System/*metabolism
Proto-Oncogene Proteins c-fos/*biosynthesis
Social Isolation/*psychology
Animals ; Female ; Gene Expression Regulation ; Male ; Mice ; Mice, Inbred C57BL ; Prefrontal Cortex/metabolism ; Proto-Oncogene Proteins c-fos/genetics ; Sex Characteristics
Czasopismo naukowe
Tytuł :
Coupling Computational and Intracellular Screening and Selection Toward Co-compatible cJun and cFos Antagonists.
Autorzy :
Lathbridge A; Department of Biology & Biochemistry , University of Bath , Claverton Down , Bath BA2 7AY , United Kingdom.
Michalowska AS; Department of Biology & Biochemistry , University of Bath , Claverton Down , Bath BA2 7AY , United Kingdom.
Mason JM; Department of Biology & Biochemistry , University of Bath , Claverton Down , Bath BA2 7AY , United Kingdom.
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Źródło :
Biochemistry [Biochemistry] 2020 Feb 04; Vol. 59 (4), pp. 530-540. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Computational Biology/*methods
Proto-Oncogene Proteins c-fos/*antagonists & inhibitors
Proto-Oncogene Proteins c-jun/*antagonists & inhibitors
Amino Acid Sequence ; Basic-Leucine Zipper Transcription Factors/chemistry ; Basic-Leucine Zipper Transcription Factors/metabolism ; Cell Proliferation ; Computer Simulation ; Dimerization ; Genes, fos/physiology ; Genes, jun/physiology ; Humans ; Oncogenes ; Peptide Library ; Peptides/metabolism ; Protein Binding ; Proto-Oncogene Proteins c-fos/metabolism ; Proto-Oncogene Proteins c-jun/metabolism ; Signal Transduction ; Transcription Factor AP-1/chemistry ; Transcription Factor AP-1/metabolism
Czasopismo naukowe
Tytuł :
Impairing activation of phospholipid synthesis by c-Fos interferes with glioblastoma cell proliferation.
Autorzy :
Prucca CG; CIQUIBIC (CONICET), Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Racca AC; CIQUIBIC (CONICET), Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Velazquez FN; CIQUIBIC (CONICET), Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Cardozo Gizzi AM; CIQUIBIC (CONICET), Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Rodríguez Berdini L; CIQUIBIC (CONICET), Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Caputto BL; CIQUIBIC (CONICET), Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
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Źródło :
The Biochemical journal [Biochem J] 2020 Dec 11; Vol. 477 (23), pp. 4675-4688.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
Glioblastoma/*metabolism
Minor Histocompatibility Antigens/*metabolism
Phospholipids/*biosynthesis
Phosphotransferases (Alcohol Group Acceptor)/*metabolism
Proto-Oncogene Proteins c-fos/*metabolism
Cell Line, Tumor ; Enzyme Activation ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; Minor Histocompatibility Antigens/genetics ; Phospholipids/genetics ; Phosphotransferases (Alcohol Group Acceptor)/genetics ; Proto-Oncogene Proteins c-fos/genetics ; Transcription Factor AP-1/genetics ; Transcription Factor AP-1/metabolism
Czasopismo naukowe
Tytuł :
Ayahuasca blocks the reinstatement of methylphenidate-induced conditioned place preference in mice: behavioral and brain Fos expression evaluations.
Autorzy :
Reis HS; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Rodrigues IRS; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Anjos-Santos A; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Libarino-Santos M; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Serra YA; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Cata-Preta EG; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Oliveira-Campos D; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Kisaki ND; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Barros-Santos T; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Yokoyama TS; Department of Pharmacology, Universidade Federal de São Paulo, Leal Prado Building, Botucatu 862 Street, 04024-002, Vila Clementino, São Paulo, SP, Brazil.
Cruz FC; Department of Pharmacology, Universidade Federal de São Paulo, Leal Prado Building, Botucatu 862 Street, 04024-002, Vila Clementino, São Paulo, SP, Brazil.
Oliveira-Lima AJ; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Barbosa PCR; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil.
Berro LF; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil. .; Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, 2500 N State St, Jackson, MS, 39216, USA. .
Marinho EAV; Department of Health Sciences, Universidade Estadual de Santa Cruz, Rod. Ilhéus/Itabuna, Km 16, Ilhéus, BA, 45662-0, Brazil. .
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2020 Nov; Vol. 237 (11), pp. 3269-3281. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Banisteriopsis*
Brain/*drug effects
Brain/*metabolism
Conditioning, Classical/*drug effects
Methylphenidate/*administration & dosage
Proto-Oncogene Proteins c-fos/*biosynthesis
Administration, Oral ; Animals ; Central Nervous System Stimulants/administration & dosage ; Conditioning, Classical/physiology ; Drug-Seeking Behavior/drug effects ; Drug-Seeking Behavior/physiology ; Gene Expression ; Hallucinogens/administration & dosage ; Male ; Mice ; Proto-Oncogene Proteins c-fos/genetics
Czasopismo naukowe
Tytuł :
Transcriptomic Changes in Endothelial Cells Triggered by Na,K-ATPase Inhibition: A Search for Upstream Na i Sensitive Genes.
Autorzy :
Klimanova EA; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Sidorenko SV; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Abramicheva PA; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Tverskoi AM; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences (RAS), 119991 Moscow, Russia.
Orlov SN; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Lopina OD; Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 27; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 27.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Cells/*metabolism
Gene Expression Profiling/*methods
Ouabain/*pharmacology
Proto-Oncogene Proteins c-fos/*genetics
Endothelial Cells/cytology ; Endothelial Cells/drug effects ; G-Quadruplexes ; Gene Expression Regulation/drug effects ; Human Umbilical Vein Endothelial Cells ; Humans ; Molecular Conformation ; Proto-Oncogene Proteins c-fos/chemistry ; Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Long-term instillation to four natural representative chrysotile of China induce the inactivation of P53 and P16 and the activation of C-JUN and C-FOS in the lung tissues of Wistar rats.
Autorzy :
Luo Y; School of Public Health, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Deng J; Medical Laboratory, Sichuan Mianyang 404 Hospital, No.2 Affiliated Hospital of North Sichuan Medical College, Mianyang 621000, Sichuan Province, China.
Cui Y; School of Public Health, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Li T; Key Laboratory of Ministry of Education, Myocardial electrical laboratory, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Bai J; School of Public Health, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Huang L; School of Public Health, Southwest Medical University, Luzhou, 646000, Sichuan, China.
Sun Y; School of Earth Science and Environmental Engineering, Southwest Jiaotong University, Chengdu, 611756, Sichuan, China.
Dong F; Key Laboratory of Solid Waste Treatment and the Resource Recycle, Southwest University of Science and Technology, Mianyang, 621010, Sichuan, China. Electronic address: .
Zhang Q; School of Public Health, Southwest Medical University, Luzhou, 646000, Sichuan, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Oct 15; Vol. 333, pp. 140-149. Date of Electronic Publication: 2020 Aug 02.
Typ publikacji :
Journal Article
MeSH Terms :
Asbestos, Serpentine/*toxicity
Cyclin-Dependent Kinase Inhibitor p16/*metabolism
Environmental Pollutants/*toxicity
JNK Mitogen-Activated Protein Kinases/*metabolism
Lung/*drug effects
Proto-Oncogene Proteins c-fos/*metabolism
Tumor Suppressor Protein p53/*metabolism
Animals ; Asbestos, Serpentine/chemistry ; Bronchoalveolar Lavage Fluid/cytology ; China ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; Cytokines/metabolism ; Environmental Pollutants/chemistry ; Gene Expression/drug effects ; Inhalation Exposure/adverse effects ; JNK Mitogen-Activated Protein Kinases/genetics ; Leukocyte Count ; Leukocytes/cytology ; Leukocytes/drug effects ; Lung/immunology ; Lung/metabolism ; Lung/pathology ; Male ; Mineral Fibers/toxicity ; Proto-Oncogene Proteins c-fos/genetics ; Rats, Wistar ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł :
Antidepressants upregulate c-Fos expression in the lateral entorhinal cortex and hippocampal dorsal subiculum: Study in rats.
Autorzy :
Ionov ID; Centre on Theoretical Problems in Physical and Chemical Pharmacology, Russian Academy of Sciences, Moscow, Russia. Electronic address: .
Pushinskaya II; Timpharm LTD, Moscow, Russia.
Gorev NP; Timpharm LTD, Moscow, Russia.
Frenkel DD; Timpharm LTD, Moscow, Russia.
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Źródło :
Brain research bulletin [Brain Res Bull] 2019 Nov; Vol. 153, pp. 102-108. Date of Electronic Publication: 2019 Aug 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antidepressive Agents/*metabolism
Antidepressive Agents/*pharmacology
Genes, fos/*drug effects
Animals ; Brain/drug effects ; Brain/metabolism ; Depression/drug therapy ; Depression/metabolism ; Entorhinal Cortex/drug effects ; Entorhinal Cortex/metabolism ; Gene Expression Regulation/drug effects ; Genes, fos/genetics ; Hippocampus/drug effects ; Hippocampus/metabolism ; Male ; Neural Pathways/metabolism ; Neurons/metabolism ; Proto-Oncogene Proteins c-fos/genetics ; Proto-Oncogene Proteins c-fos/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Hsa_circ_0001869 promotes NSCLC progression via sponging miR-638 and enhancing FOSL2 expression.
Autorzy :
Xu P; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Wang L; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Xie X; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Hu F; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Yang Q; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Hu R; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Jiang L; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Ding F; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Mei J; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Liu J; Department of Anesthesiology, Shanghai Tongji Hospital, Tongji Medical School, Tongji University, Shanghai 200065, China.
Xiao H; Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
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Źródło :
Aging [Aging (Albany NY)] 2020 Nov 20; Vol. 12 (23), pp. 23836-23848. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Non-Small-Cell Lung/*metabolism
Fos-Related Antigen-2/*metabolism
Lung Neoplasms/*metabolism
MicroRNAs/*metabolism
RNA, Circular/*metabolism
A549 Cells ; Animals ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Movement ; Cell Proliferation ; Computational Biology ; Databases, Genetic ; Disease Progression ; Female ; Fos-Related Antigen-2/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Male ; Mice, Inbred BALB C ; Mice, Nude ; MicroRNAs/genetics ; Middle Aged ; Neoplasm Invasiveness ; RNA, Circular/genetics ; Signal Transduction ; Tumor Burden
Czasopismo naukowe
Tytuł :
Deletion of Stk11 and Fos in mouse BLA projection neurons alters intrinsic excitability and impairs formation of long-term aversive memory.
Autorzy :
Levitan D; Departments of Biology, Brandeis University, Waltham, United States.
Liu C; Departments of Biology, Brandeis University, Waltham, United States.
Yang T; Departments of Biology, Brandeis University, Waltham, United States.
Shima Y; Departments of Biology, Brandeis University, Waltham, United States.
Lin JY; Departments of Psychology, Brandeis University, Waltham, United States.; Volen Center for Complex Systems, Brandeis University, Waltham, United States.
Wachutka J; Departments of Psychology, Brandeis University, Waltham, United States.
Marrero Y; Departments of Psychology, Brandeis University, Waltham, United States.
Ali Marandi Ghoddousi R; Departments of Biology, Brandeis University, Waltham, United States.
Veiga Beltrame ED; Departments of Psychology, Brandeis University, Waltham, United States.
Richter TA; Departments of Biology, Brandeis University, Waltham, United States.
Katz DB; Departments of Psychology, Brandeis University, Waltham, United States.; Volen Center for Complex Systems, Brandeis University, Waltham, United States.
Nelson SB; Departments of Biology, Brandeis University, Waltham, United States.; Volen Center for Complex Systems, Brandeis University, Waltham, United States.
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Źródło :
ELife [Elife] 2020 Aug 11; Vol. 9. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Basolateral Nuclear Complex*/chemistry
Basolateral Nuclear Complex*/cytology
Basolateral Nuclear Complex*/metabolism
Protein-Serine-Threonine Kinases*/genetics
Protein-Serine-Threonine Kinases*/metabolism
Proto-Oncogene Proteins c-fos*/genetics
Proto-Oncogene Proteins c-fos*/metabolism
Conditioning, Classical/*physiology
Memory, Long-Term/*physiology
Animals ; Female ; Gene Knockout Techniques ; Male ; Mice ; Neurons/chemistry ; Neurons/metabolism ; Taste/physiology
Czasopismo naukowe
Tytuł :
Identification of the internal ribosome entry sites in the 5'‑untranslated region of the c‑fos gene.
Autorzy :
Li H; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Chen Y; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Zhang J; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Lin Y; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Yang Z; Division of Biology, Kansas State University, Manhattan, KS 66506, USA.
Tan J; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Qiao W; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
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Źródło :
International journal of molecular medicine [Int J Mol Med] 2021 Apr; Vol. 47 (4). Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
5' Untranslated Regions/*genetics
Gene Expression Regulation/*genetics
Genes, fos/*genetics
Internal Ribosome Entry Sites/*genetics
Proto-Oncogene Proteins c-fos/*genetics
Autoantigens/metabolism ; Base Sequence/genetics ; Cell Line, Tumor ; Enterovirus A, Human/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; Protein Biosynthesis/genetics ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Rhabdomyosarcoma/metabolism ; Rhabdomyosarcoma/virology ; Ribonucleoproteins/metabolism ; Ribosomes/metabolism ; Transcription Factor AP-1/genetics ; Transcription, Genetic/genetics
Czasopismo naukowe
Tytuł :
Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance.
Autorzy :
Eagle AL; Department of Physiology, Michigan State University, East Lansing, MI, USA.
Manning CE; Department of Physiology, Michigan State University, East Lansing, MI, USA.
Williams ES; Department of Physiology, Michigan State University, East Lansing, MI, USA.
Bastle RM; Department of Neuroscience, Icahn School of Medicine, Mount Sinai, New York, NY, USA.
Gajewski PA; Department of Physiology, Michigan State University, East Lansing, MI, USA.
Garrison A; Department of Physiology, Michigan State University, East Lansing, MI, USA.
Wirtz AJ; Department of Physiology, Michigan State University, East Lansing, MI, USA.
Akguen S; Department of Physiology, Michigan State University, East Lansing, MI, USA.
Brandel-Ankrapp K; Department of Physiology, Michigan State University, East Lansing, MI, USA.
Endege W; Department of Neurology, Massachusetts General Hospital, Cambridge, MA, USA.
Boyce FM; Department of Neurology, Massachusetts General Hospital, Cambridge, MA, USA.
Ohnishi YN; Department of Pharmacology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.; Department of Medical Biophysics and Radiation Biology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.
Mazei-Robison M; Department of Physiology, Michigan State University, East Lansing, MI, USA.
Maze I; Department of Neuroscience, Icahn School of Medicine, Mount Sinai, New York, NY, USA.
Neve RL; Gene Technology Transfer Core, Massachusetts General Hospital, Cambridge, MA, USA.
Robison AJ; Department of Physiology, Michigan State University, East Lansing, MI, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Sep 08; Vol. 11 (1), pp. 4484. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Avoidance Learning/*physiology
Hippocampus/*physiology
Proto-Oncogene Proteins c-fos/*physiology
Animals ; Anxiety/metabolism ; Behavior, Animal/physiology ; Gene Knockout Techniques ; Gene Silencing ; Hippocampus/anatomy & histology ; Hippocampus/cytology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neurons/metabolism ; Proto-Oncogene Proteins c-fos/deficiency ; Proto-Oncogene Proteins c-fos/genetics ; Social Behavior ; Stress, Psychological
Czasopismo naukowe
Tytuł :
MicroRNA miR-29c-3p modulates FOS expression to repress EMT and cell proliferation while induces apoptosis in TGF-β2-treated lens epithelial cells regulated by lncRNA KCNQ1OT1.
Autorzy :
Yao L; Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, China.
Yang L; Tianjin Key Laboratory of Tianjin Nankai Hospital, Tianjin, China.
Song H; Department of Ophthalmology, Tianjin Eye Hospital, Tianjin, China.
Liu T; Department of Ophthalmology, Beijing Capital International Airport Hospital, Beijing, China.
Yan H; Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Sep; Vol. 129, pp. 110290. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Cataract/*metabolism
Cell Proliferation/*drug effects
Epithelial Cells/*drug effects
Epithelial-Mesenchymal Transition/*drug effects
Lens, Crystalline/*drug effects
MicroRNAs/*metabolism
Proto-Oncogene Proteins c-fos/*metabolism
Transforming Growth Factor beta2/*pharmacology
Case-Control Studies ; Cataract/genetics ; Cataract/pathology ; Cell Line ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Gene Expression Regulation ; Humans ; Lens, Crystalline/metabolism ; Lens, Crystalline/pathology ; MicroRNAs/genetics ; Potassium Channels, Voltage-Gated/genetics ; Potassium Channels, Voltage-Gated/metabolism ; Proto-Oncogene Proteins c-fos/genetics ; Signal Transduction
Czasopismo naukowe

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