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Wyświetlanie 1-15 z 15
Tytuł :
MOBP and HIP1 in multiple system atrophy: new α-synuclein partners in glial cytoplasmic inclusions implicated in the disease pathogenesis.
Autorzy :
Bettencourt C; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.
Miki Y; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Piras IS; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
de Silva R; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, UK.
Foti SC; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Talboom JS; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
Revesz T; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Lashley T; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Balazs R; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Viré E; Institute of Prion Diseases, MRC Prion Unit at UCL, Courtauld Building, 33 Cleveland Street, London, UK.
Warner TT; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London, UK.
Huentelman MJ; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
Holton JL; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.
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Źródło :
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2020 Dec 23. Date of Electronic Publication: 2020 Dec 23.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Heterogeneous Nuclear Ribonucleoproteins: Implications in Neurological Diseases.
Autorzy :
Low YH; The Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.; Duke-NUS Medical School, Singapore, Singapore.
Asi Y; The Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
Foti SC; The Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
Lashley T; The Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK. .; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK. .
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Źródło :
Molecular neurobiology [Mol Neurobiol] 2020 Sep 30. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Hippocampal α-synuclein pathology correlates with memory impairment in multiple system atrophy.
Autorzy :
Miki Y; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.; Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Foti SC; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.
Hansen D; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.
Strand KM; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.
Asi YT; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.
Tsushima E; Department of Comprehensive Rehabilitation Science, Hirosaki University Graduate School of Health Sciences, Hirosaki 036-8564, Japan.
Jaunmuktane Z; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.
Lees AJ; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.
Warner TT; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.
Quinn N; UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
Ling H; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.
Holton JL; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK.
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Źródło :
Brain : a journal of neurology [Brain] 2020 Jun 01; Vol. 143 (6), pp. 1798-1810.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Epigenomics and transcriptomics analyses of multiple system atrophy brain tissue supports a role for inflammatory processes in disease pathogenesis.
Autorzy :
Bettencourt C; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK. .; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square Brain Bank for Neurological Disorders, 1 Wakefield street, London, WC1N 1PJ, UK. .
Piras IS; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
Foti SC; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Talboom J; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
Miki Y; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Lashley T; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Balazs R; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Viré E; Institute of Prion Diseases, MRC Prion Unit at UCL, Courtauld Building, 33 Cleveland Street, London, UK.
Warner TT; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square Brain Bank for Neurological Disorders, 1 Wakefield street, London, WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, UK.
Huentelman MJ; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
Holton JL; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square Brain Bank for Neurological Disorders, 1 Wakefield street, London, WC1N 1PJ, UK.
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Źródło :
Acta neuropathologica communications [Acta Neuropathol Commun] 2020 May 14; Vol. 8 (1), pp. 71. Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Raport
Tytuł :
Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges.
Autorzy :
Shibata-Germanos S; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK.
Goodman JR; Department of Anaesthesiology and Perioperative Medicine, Oregon Health & Science University, Portland, OR, USA.; Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR, USA.
Grieg A; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK.
Trivedi CA; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK.
Benson BC; The Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
Foti SC; The Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
Faro A; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK.
Castellan RFP; UCL Institute of Ophthalmology, University College London, London, UK.
Correra RM; UCL Institute of Ophthalmology, University College London, London, UK.
Barber M; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK.
Ruhrberg C; UCL Institute of Ophthalmology, University College London, London, UK.
Weller RO; Clinical Neurosciences (Neuropathology), Faculty of Medicine, Southampton University Hospitals, Southampton, SO16 6YD, UK.
Lashley T; The Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
Iliff JJ; Department of Anaesthesiology and Perioperative Medicine, Oregon Health & Science University, Portland, OR, USA.; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA.
Hawkins TA; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK.
Rihel J; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK. .
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Źródło :
Acta neuropathologica [Acta Neuropathol] 2020 Feb; Vol. 139 (2), pp. 383-401. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*pathology
Endothelial Cells/*pathology
Endothelial Cells/*physiology
Lymphatic System/*pathology
Meninges/*pathology
Adult ; Aged ; Aged, 80 and over ; Amyloid beta-Peptides ; Animals ; Female ; Humans ; Male ; Mice ; Zebrafish
Czasopismo naukowe
Tytuł :
White matter DNA methylation profiling reveals deregulation of HIP1, LMAN2, MOBP, and other loci in multiple system atrophy.
Autorzy :
Bettencourt C; The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK. .; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK. .
Foti SC; The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Miki Y; The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Botia J; Departamento de Ingeniería de la Información y las Comunicaciones, Universidad de Murcia, Murcia, Spain.
Chatterjee A; The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.
Warner TT; The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, UK.
Revesz T; The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Lashley T; The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Balazs R; The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.
Viré E; Institute of Prion Diseases, MRC Prion Unit At UCL, Courtauld Building, 33 Cleveland Street, London, UK.
Holton JL; The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.
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Źródło :
Acta neuropathologica [Acta Neuropathol] 2020 Jan; Vol. 139 (1), pp. 135-156. Date of Electronic Publication: 2019 Sep 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Improving diagnostic accuracy of multiple system atrophy: a clinicopathological study.
Autorzy :
Miki Y; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London, UK.; Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Foti SC; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London, UK.
Asi YT; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London, UK.
Tsushima E; Department of Comprehensive Rehabilitation Science, Hirosaki University Graduate School of Health Sciences, Hirosaki, Japan.
Quinn N; UCL Queen Square Institute of Neurology, London, UK.
Ling H; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London, UK.
Holton JL; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London, UK.
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Źródło :
Brain : a journal of neurology [Brain] 2019 Sep 01; Vol. 142 (9), pp. 2813-2827.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Multiple System Atrophy/*pathology
Multiple System Atrophy/*physiopathology
Adult ; Aged ; Aged, 80 and over ; Diagnosis, Differential ; Female ; Humans ; Lewy Body Disease/diagnosis ; Lewy Body Disease/pathology ; Lewy Body Disease/physiopathology ; Male ; Middle Aged ; Multiple System Atrophy/diagnosis ; Retrospective Studies ; Supranuclear Palsy, Progressive/diagnosis ; Supranuclear Palsy, Progressive/pathology ; Supranuclear Palsy, Progressive/physiopathology ; Tissue Banks/standards
Czasopismo naukowe
Tytuł :
Cerebral mitochondrial electron transport chain dysfunction in multiple system atrophy and Parkinson's disease.
Autorzy :
Foti SC; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK.; Department of Neurodegenerative Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.
Hargreaves I; UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, WC1N 3BG, United Kingdom.; Liverpool John Moores University, School of Pharmacy and Biomedical Sciences, Liverpool, L3 3AF, United Kingdom.
Carrington S; UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, WC1N 3BG, United Kingdom.
Kiely AP; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK.
Houlden H; UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, WC1N 3BG, United Kingdom.
Holton JL; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK. .
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Źródło :
Scientific reports [Sci Rep] 2019 Apr 25; Vol. 9 (1), pp. 6559. Date of Electronic Publication: 2019 Apr 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Electron Transport/*physiology
Multiple System Atrophy/*metabolism
Parkinson Disease/*metabolism
Cerebellum/metabolism ; Humans ; Immunoblotting ; Inclusion Bodies/metabolism ; Mitochondria/metabolism ; Ubiquinone/analogs & derivatives ; Ubiquinone/metabolism ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS.
Autorzy :
Gittings LM; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, 1 Wakefield Street, London, WC1N 1PJ, UK.; UK Dementia Research Institute at UCL, UCL Queen Square Institute of Neurology, University College London, London, UK.
Foti SC; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, 1 Wakefield Street, London, WC1N 1PJ, UK.
Benson BC; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, 1 Wakefield Street, London, WC1N 1PJ, UK.
Gami-Patel P; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, 1 Wakefield Street, London, WC1N 1PJ, UK.
Isaacs AM; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.; UK Dementia Research Institute at UCL, UCL Queen Square Institute of Neurology, University College London, London, UK.
Lashley T; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK. .; Queen Square Brain Bank for Neurological Disorders, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, 1 Wakefield Street, London, WC1N 1PJ, UK. .
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Źródło :
Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Feb 12; Vol. 7 (1), pp. 18. Date of Electronic Publication: 2019 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Frontotemporal Lobar Degeneration/*metabolism
Heterogeneous-Nuclear Ribonucleoproteins/*metabolism
Hippocampus/*pathology
RNA-Binding Protein FUS/*metabolism
Temporal Lobe/*pathology
Adult ; Aged ; Aged, 80 and over ; Female ; Frontotemporal Lobar Degeneration/pathology ; Hippocampus/metabolism ; Humans ; Inclusion Bodies/metabolism ; Inclusion Bodies/pathology ; Intranuclear Inclusion Bodies/metabolism ; Intranuclear Inclusion Bodies/pathology ; Male ; Middle Aged ; Temporal Lobe/metabolism
Czasopismo naukowe
Tytuł :
TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates.
Autorzy :
Laferrière F; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Maniecka Z; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Pérez-Berlanga M; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Hruska-Plochan M; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Gilhespy L; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Hock EM; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Wagner U; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.
Afroz T; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
Boersema PJ; Institute of Biochemistry, Department of Biology, ETH Zurich (ETHZ), Zurich, Switzerland.
Barmettler G; Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland.
Foti SC; Queen Square Brain Bank for Neurological diseases, Department of Movement Disorders, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
Asi YT; Queen Square Brain Bank for Neurological diseases, Department of Movement Disorders, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
Isaacs AM; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, UCL Institute of Neurology, London, UK.
Al-Amoudi A; Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, Basel, Switzerland.
Lewis A; Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, Basel, Switzerland.
Stahlberg H; Center for Cellular Imaging and NanoAnalytics (C-CINA), Biozentrum, University of Basel, Basel, Switzerland.
Ravits J; Department of Neuroscience, University of California, San Diego, La Jolla, CA, USA.
De Giorgi F; INSERM U1084, Laboratoire des Neurosciences Expérimentales et Cliniques, Université de Poitiers, Poitiers, France.; Université de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, Bordeaux, France.; CNRS, Institut des Maladies Neurodégénératives, UMR 5293, Bordeaux, France.
Ichas F; INSERM U1084, Laboratoire des Neurosciences Expérimentales et Cliniques, Université de Poitiers, Poitiers, France.; Université de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, Bordeaux, France.; CNRS, Institut des Maladies Neurodégénératives, UMR 5293, Bordeaux, France.
Bezard E; Université de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, Bordeaux, France.; CNRS, Institut des Maladies Neurodégénératives, UMR 5293, Bordeaux, France.
Picotti P; Center for Microscopy and Image Analysis, University of Zurich, Zurich, Switzerland.
Lashley T; Queen Square Brain Bank for Neurological diseases, Department of Movement Disorders, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
Polymenidou M; Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland. .
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Źródło :
Nature neuroscience [Nat Neurosci] 2019 Jan; Vol. 22 (1), pp. 65-77. Date of Electronic Publication: 2018 Dec 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*metabolism
DNA-Binding Proteins/*metabolism
Frontotemporal Lobar Degeneration/*metabolism
Protein Aggregates/*physiology
Animals ; Brain/pathology ; Disease Progression ; Frontotemporal Lobar Degeneration/pathology ; HEK293 Cells ; Humans ; Inclusion Bodies/metabolism ; Inclusion Bodies/pathology ; Mass Spectrometry ; Mice ; Neurons/metabolism ; Neurons/pathology ; Phosphorylation
Czasopismo naukowe
Tytuł :
Immunohistochemical and Molecular Investigations Show Alteration in the Inflammatory Profile of Multiple System Atrophy Brain.
Autorzy :
Kiely AP; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Murray CE; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Foti SC; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Benson BC; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Courtney R; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Strand C; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Lashley T; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Holton JL; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
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Źródło :
Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2018 Jul 01; Vol. 77 (7), pp. 598-607.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*pathology
Inflammation/*genetics
Inflammation/*pathology
Multiple System Atrophy/*genetics
Multiple System Atrophy/*pathology
Antigens, CD/biosynthesis ; Antigens, CD/genetics ; Antigens, Differentiation, Myelomonocytic/biosynthesis ; Antigens, Differentiation, Myelomonocytic/genetics ; Arginase/biosynthesis ; Arginase/genetics ; Calcium-Binding Proteins ; Chemokines/analysis ; Chemokines/biosynthesis ; Corpus Striatum/pathology ; Cytokines/analysis ; Cytokines/biosynthesis ; DNA-Binding Proteins/biosynthesis ; DNA-Binding Proteins/genetics ; Gene Expression Regulation/genetics ; Humans ; Immunohistochemistry ; Microfilament Proteins ; Microglia/pathology ; Olivopontocerebellar Atrophies/pathology ; Substantia Nigra/pathology
Czasopismo naukowe
Tytuł :
Molecular biomarkers of Alzheimer's disease: progress and prospects.
Autorzy :
Lashley T; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.
Schott JM; Dementia Research Centre, UCL Institute of Neurology, London WC1N 3BG, UK.
Weston P; Dementia Research Centre, UCL Institute of Neurology, London WC1N 3BG, UK.
Murray CE; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.
Wellington H; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.; UK Dementia Research Institute, London WC1N 3BG, UK.
Keshavan A; Dementia Research Centre, UCL Institute of Neurology, London WC1N 3BG, UK.
Foti SC; Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK.
Foiani M; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.; UK Dementia Research Institute, London WC1N 3BG, UK.
Toombs J; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.; UK Dementia Research Institute, London WC1N 3BG, UK.
Rohrer JD; Dementia Research Centre, UCL Institute of Neurology, London WC1N 3BG, UK.
Heslegrave A; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.; UK Dementia Research Institute, London WC1N 3BG, UK.
Zetterberg H; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK .; UK Dementia Research Institute, London WC1N 3BG, UK.; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal S-431 80, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal S-431 80, Sweden.
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Źródło :
Disease models & mechanisms [Dis Model Mech] 2018 May 08; Vol. 11 (5). Date of Electronic Publication: 2018 May 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Alzheimer Disease/*diagnosis
Biomarkers/*metabolism
Alzheimer Disease/blood ; Alzheimer Disease/cerebrospinal fluid ; Alzheimer Disease/pathology ; Animals ; Axons/pathology ; Biomarkers/blood ; Biomarkers/cerebrospinal fluid ; Humans ; Nerve Degeneration/pathology ; Neuroglia/metabolism ; Neuroglia/pathology ; Synapses/metabolism ; Synapses/pathology
Czasopismo naukowe
    Wyświetlanie 1-15 z 15

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