- Tytuł:
-
Galectin-3 impairment of MYCN-dependent
apoptosis -sensitive phenotype is antagonized by nutlin-3 in neuroblastoma cells. - Autorzy:
- Źródło:
- PloS one [PLoS One] 2012; Vol. 7 (11), pp. e49139. Date of Electronic Publication: 2012 Nov 09.
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Apoptosis *
Galectin 3/*metabolism
Imidazoles/*pharmacology
Neuroblastoma/*metabolism
Neuroblastoma/*pathology
Nuclear Proteins/*metabolism
Oncogene Proteins/*metabolism
Piperazines/*pharmacology
Carrier Proteins/metabolism ; Cell Line, Tumor ; Cytoprotection/drug effects ; DNA Damage ; Galectin 3/genetics ; Gene Amplification ; Gene Dosage ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Knockdown Techniques ; Humans ; Models, Biological ; N-Myc Proto-Oncogene Protein ; Neuroblastoma/genetics ; Phenotype ; Protein Serine-Threonine Kinases/metabolism ; Protein Transport/drug effects ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe