Autor: "Freitag, DF" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Correction to: The role of machine learning in clinical research: transforming the future of evidence generation.
Autorzy:: Weissler EH; Duke Clinical Research Institute, Duke University School of Medicine, Box 2834, Durham, NC, 27701, USA. .
Naumann T; Microsoft Research, Cambridge, MA, USA.
Andersson T; AstraZeneca, Gothenburg, Sweden.
Ranganath R; Courant Institute of Mathematical Science, New York University, New York, NY, USA.
Elemento O; Englander Institute for Precision Medicine, Weill Cornell Medical College, New York, NY, USA.
Luo Y; Northwestern University Clinical and Translational Sciences Institute, Northwestern University, Chicago, IL, USA.
Freitag DF; Division Pharmaceuticals, Open Innovation and Digital Technologies, Bayer AG, Wuppertal, Germany.
Benoit J; University of Alberta, Edmonton, Alberta, Canada.
Hughes MC; Department of Computer Science, Tufts University, Medford, MA, USA.
Khan F; AstraZeneca, Gothenburg, Sweden.
Slater P; Billion Minds, Inc., Seattle, WA, USA.
Shameer K; AstraZeneca, Gothenburg, Sweden.
Roe M; Verana Health, San Francisco, CA, USA.
Hutchison E; AstraZeneca, Gothenburg, Sweden.
Kollins SH; Duke Clinical Research Institute, Duke University School of Medicine, Box 2834, Durham, NC, 27701, USA.
Broedl U; Boehringer-Ingelheim, Burlington, Canada.
Meng Z; Sanofi, Cambridge, MA, USA.
Wong JL; Sanofi, Washington, DC, USA.
Curtis L; Duke Clinical Research Institute, Duke University School of Medicine, Box 2834, Durham, NC, 27701, USA.
Huang E; Duke Clinical Research Institute, Duke University School of Medicine, Box 2834, Durham, NC, 27701, USA.; Duke Forge, Durham, NC, USA.
Ghassemi M; Vector Institute, University of Toronto, Toronto, Ontario, Canada.; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA.; CIFAR AI Chair, Vector Institute, Toronto, Ontario, Canada.; Pokaż więcej
Źródło:: Trials [Trials] 2021 Sep 06; Vol. 22 (1), pp. 593. Date of Electronic Publication: 2021 Sep 06.
Typ publikacji:: Published Erratum

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Skocz do pozycji: 2.

Tytuł:: The role of machine learning in clinical research: transforming the future of evidence generation.
Autorzy:: Weissler EH; Duke Clinical Research Institute, Duke University School of Medicine, Box 2834, Durham, NC, 27701, USA. .
Naumann T; Microsoft Research, Cambridge, MA, USA.
Andersson T; AstraZeneca, Gothenburg, Sweden.
Ranganath R; Courant Institute of Mathematical Science, New York University, New York, NY, USA.
Elemento O; Englander Institute for Precision Medicine, Weill Cornell Medical College, New York, NY, USA.
Luo Y; Northwestern University Clinical and Translational Sciences Institute, Northwestern University, Chicago, IL, USA.
Freitag DF; Division Pharmaceuticals, Open Innovation and Digital Technologies, Bayer AG, Wuppertal, Germany.
Benoit J; University of Alberta, Edmonton, Alberta, Canada.
Hughes MC; Department of Computer Science, Tufts University, Medford, MA, USA.
Khan F; AstraZeneca, Gothenburg, Sweden.
Slater P; Billion Minds, Inc., Seattle, WA, USA.
Shameer K; AstraZeneca, Gothenburg, Sweden.
Roe M; Verana Health, San Francisco, CA, USA.
Hutchison E; AstraZeneca, Gothenburg, Sweden.
Kollins SH; Duke Clinical Research Institute, Duke University School of Medicine, Box 2834, Durham, NC, 27701, USA.
Broedl U; Boehringer-Ingelheim, Burlington, Canada.
Meng Z; Sanofi, Cambridge, MA, USA.
Wong JL; Sanofi, Washington, DC, USA.
Curtis L; Duke Clinical Research Institute, Duke University School of Medicine, Box 2834, Durham, NC, 27701, USA.
Huang E; Duke Clinical Research Institute, Duke University School of Medicine, Box 2834, Durham, NC, 27701, USA.; Duke Forge, Durham, NC, USA.
Ghassemi M; Vector Institute, University of Toronto, Toronto, Ontario, Canada.; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA.; CIFAR AI Chair, Vector Institute, Toronto, Ontario, Canada.; Pokaż więcej
Źródło:: Trials [Trials] 2021 Aug 16; Vol. 22 (1), pp. 537. Date of Electronic Publication: 2021 Aug 16.
Typ publikacji:: Letter; Review
MeSH Terms:: Artificial Intelligence*
Machine Learning*
Humans ; United States ; United States Food and Drug Administration

Recenzja

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Skocz do pozycji: 3.

Tytuł:: Machine learning for subtype definition and risk prediction in heart failure, acute coronary syndromes and atrial fibrillation: systematic review of validity and clinical utility.
Autorzy:: Banerjee A; Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK. .; Health Data Research UK, University College London, London, UK. .; University College London Hospitals NHS Trust, 235 Euston Road, London, UK. .; Barts Health NHS Trust, The Royal London Hospital, Whitechapel Rd, London, UK. .
Chen S; Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.; Health Data Research UK, University College London, London, UK.
Fatemifar G; Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.; Health Data Research UK, University College London, London, UK.
Zeina M; Medical School, King's College London, London, UK.
Lumbers RT; Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.; Health Data Research UK, University College London, London, UK.; University College London Hospitals NHS Trust, 235 Euston Road, London, UK.
Mielke J; Bayer AG, Division Pharmaceuticals, Open Innovation & Digital Technologies, Wuppertal, Germany.
Gill S; University of Birmingham Institute of Cardiovascular Sciences and University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Kotecha D; University of Birmingham Institute of Cardiovascular Sciences and University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.; Department of Cardiology, University Medical Centre Utrecht, Utrecht, the Netherlands.
Freitag DF; Bayer AG, Division Pharmaceuticals, Open Innovation & Digital Technologies, Wuppertal, Germany.
Denaxas S; Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.; Health Data Research UK, University College London, London, UK.; The Alan Turing Institute, London, UK.
Hemingway H; Institute of Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK.; Health Data Research UK, University College London, London, UK.; University College London Hospitals Biomedical Research Centre (UCLH BRC), London, UK.; Pokaż więcej
Źródło:: BMC medicine [BMC Med] 2021 Apr 06; Vol. 19 (1), pp. 85. Date of Electronic Publication: 2021 Apr 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms:: Acute Coronary Syndrome*/diagnosis
Acute Coronary Syndrome*/epidemiology
Atrial Fibrillation*/diagnosis
Atrial Fibrillation*/epidemiology
Heart Failure*/diagnosis
Heart Failure*/epidemiology
Cost-Benefit Analysis ; Humans ; Machine Learning

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Skocz do pozycji: 4.

Tytuł:: Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions.
Autorzy:: Burgess S; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.
Freitag DF; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.
Khan H; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.
Gorman DN; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.
Thompson SG; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Oct 10; Vol. 9 (10), pp. e108891. Date of Electronic Publication: 2014 Oct 10 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mendelian Randomization Analysis*
Coronary Artery Disease/*epidemiology
Coronary Artery Disease/*genetics
Cholesterol, HDL/blood ; Cholesterol, HDL/genetics ; Cholesterol, LDL/blood ; Cholesterol, LDL/genetics ; Coronary Artery Disease/blood ; Genetic Variation ; Humans ; Risk Factors ; Triglycerides/blood ; Triglycerides/genetics

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Tytuł:: Common variants associated with plasma triglycerides and risk for coronary artery disease.
Autorzy:: Do R; 1] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. [4] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.
Willer CJ
Schmidt EM
Sengupta S
Gao C
Peloso GM
Gustafsson S
Kanoni S
Ganna A
Chen J
Buchkovich ML
Mora S
Beckmann JS
Bragg-Gresham JL
Chang HY
Demirkan A
Den Hertog HM
Donnelly LA
Ehret GB
Esko T
Feitosa MF
Ferreira T
Fischer K
Fontanillas P
Fraser RM
Freitag DF
Gurdasani D
Heikkilä K
Hyppönen E
Isaacs A
Jackson AU
Johansson A
Johnson T
Kaakinen M
Kettunen J
Kleber ME
Li X
Luan J
Lyytikäinen LP
Magnusson PK
Mangino M
Mihailov E
Montasser ME
Müller-Nurasyid M
Nolte IM
O'Connell JR
Palmer CD
Perola M
Petersen AK
Sanna S
Saxena R
Service SK
Shah S
Shungin D
Sidore C
Song C
Strawbridge RJ
Surakka I
Tanaka T
Teslovich TM
Thorleifsson G
Van den Herik EG
Voight BF
Volcik KA
Waite LL
Wong A
Wu Y
Zhang W
Absher D
Asiki G
Barroso I
Been LF
Bolton JL
Bonnycastle LL
Brambilla P
Burnett MS
Cesana G
Dimitriou M
Doney AS
Döring A
Elliott P
Epstein SE
Eyjolfsson GI
Gigante B
Goodarzi MO
Grallert H
Gravito ML
Groves CJ
Hallmans G
Hartikainen AL
Hayward C
Hernandez D
Hicks AA
Holm H
Hung YJ
Illig T
Jones MR
Kaleebu P
Kastelein JJ
Khaw KT
Kim E
Klopp N
Komulainen P
Kumari M
Langenberg C
Lehtimäki T
Lin SY
Lindström J
Loos RJ
Mach F
McArdle WL
Meisinger C
Mitchell BD
Müller G
Nagaraja R
Narisu N
Nieminen TV
Nsubuga RN
Olafsson I
Ong KK
Palotie A
Papamarkou T
Pomilla C
Pouta A
Rader DJ
Reilly MP
Ridker PM
Rivadeneira F
Rudan I
Ruokonen A
Samani N
Scharnagl H
Seeley J
Silander K
Stančáková A
Stirrups K
Swift AJ
Tiret L
Uitterlinden AG
van Pelt LJ
Vedantam S
Wainwright N
Wijmenga C
Wild SH
Willemsen G
Wilsgaard T
Wilson JF
Young EH
Zhao JH
Adair LS
Arveiler D
Assimes TL
Bandinelli S
Bennett F
Bochud M
Boehm BO
Boomsma DI
Borecki IB
Bornstein SR
Bovet P
Burnier M
Campbell H
Chakravarti A
Chambers JC
Chen YD
Collins FS
Cooper RS
Danesh J
Dedoussis G
de Faire U
Feranil AB
Ferrières J
Ferrucci L
Freimer NB
Gieger C
Groop LC
Gudnason V
Gyllensten U
Hamsten A
Harris TB
Hingorani A
Hirschhorn JN
Hofman A
Hovingh GK
Hsiung CA
Humphries SE
Hunt SC
Hveem K
Iribarren C
Järvelin MR
Jula A
Kähönen M
Kaprio J
Kesäniemi A
Kivimaki M
Kooner JS
Koudstaal PJ
Krauss RM
Kuh D
Kuusisto J
Kyvik KO
Laakso M
Lakka TA
Lind L
Lindgren CM
Martin NG
März W
McCarthy MI
McKenzie CA
Meneton P
Metspalu A
Moilanen L
Morris AD
Munroe PB
Njølstad I
Pedersen NL
Power C
Pramstaller PP
Price JF
Psaty BM
Quertermous T
Rauramaa R
Saleheen D
Salomaa V
Sanghera DK
Saramies J
Schwarz PE
Sheu WH
Shuldiner AR
Siegbahn A
Spector TD
Stefansson K
Strachan DP
Tayo BO
Tremoli E
Tuomilehto J
Uusitupa M
van Duijn CM
Vollenweider P
Wallentin L
Wareham NJ
Whitfield JB
Wolffenbuttel BH
Altshuler D
Ordovas JM
Boerwinkle E
Palmer CN
Thorsteinsdottir U
Chasman DI
Rotter JI
Franks PW
Ripatti S
Cupples LA
Sandhu MS
Rich SS
Boehnke M
Deloukas P
Mohlke KL
Ingelsson E
Abecasis GR
Daly MJ
Neale BM
Kathiresan S; Pokaż więcej
Źródło:: Nature genetics [Nat Genet] 2013 Nov; Vol. 45 (11), pp. 1345-52. Date of Electronic Publication: 2013 Oct 06.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cholesterol, HDL/*genetics
Cholesterol, LDL/*genetics
Coronary Artery Disease/*blood
Triglycerides/*blood
Triglycerides/*genetics
Biological Transport ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Coronary Artery Disease/epidemiology ; Coronary Artery Disease/genetics ; Humans ; Polymorphism, Single Nucleotide ; Risk Factors ; Triglycerides/metabolism

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Skocz do pozycji: 6.

Tytuł:: Discovery and refinement of loci associated with lipid levels.
Autorzy:: Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
Schmidt EM; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.
Sengupta S; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Broad Institute, Program in Medical and Population Genetics, Cambridge, Massachusetts 02142, USA.
Gustafsson S; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.; Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Kanoni S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.
Ganna A; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.; Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Chen J; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
Buchkovich ML; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 USA.
Mora S; Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave., Boston MA 02215, USA.; Harvard Medical School, Boston MA 02115, USA.
Beckmann JS; Service of Medical Genetics, Lausanne University Hospital, Lausanne, Switzerland.; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.
Bragg-Gresham JL; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
Chang HY; Division of Preventive Medicine and Health Services Research, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Demirkan A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Den Hertog HM; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.
Do R; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
Donnelly LA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School. Dundee, DD1 9SY, United Kingdom.
Ehret GB; Cardiology, Department of Specialities of Medicine, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, Switzerland.; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Esko T; Broad Institute, Program in Medical and Population Genetics, Cambridge, Massachusetts 02142, USA.; Estonian Genome Center of the University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Feitosa MF; Department of Genetics, Washington University School of Medicine, USA.
Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, United Kingdom.
Fischer K; Estonian Genome Center of the University of Tartu, Tartu, Estonia.
Fontanillas P; Broad Institute, Program in Medical and Population Genetics, Cambridge, Massachusetts 02142, USA.
Fraser RM; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, United Kingdom.
Freitag DF; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Gurdasani D; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Heikkilä K; Hjelt Institute, Department of Public Health, University of Helsinki, Finland.
Hyppönen E; Centre For Paediatric Epidemiology and Biostatistics/MRC Centre of Epidemiology for Child Health, University College of London Institute of Child Health, London, United Kingdom.
Isaacs A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Centre for Medical Systems Biology, Leiden, the Netherlands.
Jackson AU; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
Johansson Å; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Johnson T; Genome Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Clinical Pharmacology, NIHR Cardiovascular Biomedical Research Unit, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry Queen Mary University of London, London, UK.
Kaakinen M; Biocenter Oulu, University of Oulu, Oulu, Finland.; Institute of Health Sciences, University of Oulu, Finland.
Kettunen J; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland.; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland.
Kleber ME; Department of Internal Medicine II - Cardiology, University of Ulm Medical Centre, Ulm, Germany.; Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty of Mannheim, University of Heidelberg, Ludolf-Krehl-Strasse 7-11, 68167 Mannheim, Germany.
Li X; Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, United Kingdom.
Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere 33014, Finland.
Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Mihailov E; Estonian Genome Center of the University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Montasser ME; Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland.
Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians University, Munich, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-University of Munich, Munich, Germany.
Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, The Netherlands.
O'Connell JR; Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland.
Palmer CD; Broad Institute, Program in Medical and Population Genetics, Cambridge, Massachusetts 02142, USA.; Division of Endocrinology, Children's Hospital Boston, Massachusetts 02115, USA.; Division of Genetics, Program in Genomics, Children's Hospital, Boston, Massachusetts 02115, USA.
Perola M; Estonian Genome Center of the University of Tartu, Tartu, Estonia.; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland.; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland.
Petersen AK; Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.
Sanna S; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, 09042, Italy.
Saxena R; Massachusetts General Hospital/Broad Institute, Harvard University, Cambridge, MA, USA.
Service SK; Center for Neurobehavioral Genetics, The Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.
Shah S; Genetic Epidemiology Group, Deparment of Epidemiology and Public Health, UCL, London WC1E 6BT, United Kingdom.
Shungin D; Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Scania University Hosptial, Malmö, Sweden.; Department of Odontology, Umeå University, Umeå, Sweden.; Department of Public Health and Primary Care, Unit of Medicine, Umeå University, Umeå, Sweden.
Sidore C; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, 09042, Italy.; Dipartimento di Scienze Biomediche, Universita di Sassari, 07100 SS, Italy.
Song C; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.; Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Strawbridge RJ; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
Surakka I; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland.; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland.
Tanaka T; Clinical Research Branch, National Institute Health, Baltimore, MD, USA.
Teslovich TM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
Thorleifsson G; deCODE Genetics/Amgen, 101 Reykjavik, Iceland.
Van den Herik EG; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.
Voight BF; Department of Genetics, University of Pennsylvania - School of Medicine, Philadelphia PA, 19104, USA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - School of Medicine, Philadelphia PA, 19104, USA.
Volcik KA; Human Genetics Center, University of Texas Health Science Center - School of Public Health, Houston, TX 77030, USA.
Waite LL; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
Wong A; MRC Unit for Lifelong Health and Ageing, 33 Bedford Place, London, WC1B 5JU, United Kingdom.
Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 USA.
Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Ealing Hospital, Southall, Middlesex UB1 3HW, United Kingdom.
Absher D; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
Asiki G; MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda.
Barroso I; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.; University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Level 4, Institute of Metabolic Science Box 289 Addenbrooke's Hospital Cambridge CB2 OQQ, UK.
Been LF; Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Bolton JL; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, United Kingdom.
Bonnycastle LL; Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.
Brambilla P; Department of Experimental Medicine, University of Milano Bicocca, Italy.
Burnett MS; MedStar Health Research Institute, 6525 Belcrest Road, Suite 700, Hyattsville, MD 20782, USA.
Cesana G; Research Centre on Public Health, University of Milano Bicocca, Italy.
Dimitriou M; Department of Dietetics-Nutrition, Harokopio University, 70 El. Venizelou Str, Athens, Greece.
Doney ASF; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School. Dundee, DD1 9SY, United Kingdom.
Döring A; Institute of Epidemiology I, Helmholtz Zentrum München, Neuherberg 85764, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, Neuherberg 85764, Germany.
Elliott P; Institute of Health Sciences, University of Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, UK.
Epstein SE; MedStar Health Research Institute, 6525 Belcrest Road, Suite 700, Hyattsville, MD 20782, USA.
Ingi Eyjolfsson G; The Laboratory in Mjodd, 108 Reykjavik, Iceland.
Gigante B; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Goodarzi MO; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.
Gravito ML; Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Groves CJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, OX3 7LJ, United Kingdom.
Hallmans G; Department of Public Health and Clinical Medicine, Nutritional research, Umeå University, Umeå, Sweden.
Hartikainen AL; Department of Clinical Sciences/Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland.
Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA.
Hicks AA; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany.
Holm H; deCODE Genetics/Amgen, 101 Reykjavik, Iceland.
Hung YJ; Division of Endocrinology & Metabolism, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Illig T; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover 30625, Germany.
Jones MR; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Kaleebu P; MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda.
Kastelein JJP; Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Khaw KT; Clinical Gerontology Unit, University of Cambridge, Cambridge, United Kingdom.
Kim E; Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Klopp N; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover 30625, Germany.
Komulainen P; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
Kumari M; Genetic Epidemiology Group, Deparment of Epidemiology and Public Health, UCL, London WC1E 6BT, United Kingdom.
Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, United Kingdom.
Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere 33014, Finland.
Lin SY; Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Lindström J; Diabetes Prevention Unit, National Institute for Health and Welfare, 00271 Helsinki, Finland.
Loos RJF; MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, United Kingdom.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, USA.; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at ount Sinai, New York, USA.; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York.
Mach F; Cardiology, Department of Specialities of Medicine, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, Switzerland.
McArdle WL; School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, United Kingdom.
Meisinger C; Institute of Epidemiology I, Helmholtz Zentrum München, Neuherberg 85764, Germany.
Mitchell BD; Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland.
Müller G; Institute for Medical Informatics and Biometrics, University of Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, 01307 Dresden, Germany.
Nagaraja R; Laboratory of Genetics, National Institute on Aging, Baltimore, MD21224, USA.
Narisu N; Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.
Nieminen TVM; Department of Clinical Pharmacology, University of Tampere School of Medicine, Tamperew 33014, Finland.; Department of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland.; Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.
Nsubuga RN; MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda.
Olafsson I; Department of Clinical Biochemistry, Landspitali University Hospital, 101 Reykjavik, Iceland.
Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, United Kingdom.; MRC Unit for Lifelong Health and Ageing, 33 Bedford Place, London, WC1B 5JU, United Kingdom.
Palotie A; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland.; Department of Medical Genetics, Haartman Institute, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Genetic Epidemiology Group, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United ingdom.
Papamarkou T; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; Department of Statistical Sciences, University College of London, London, United Kingdom.
Pomilla C; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Pouta A; Department of Clinical Sciences/Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland.; National Institute for Health and Welfare, Oulu, Finland.
Rader DJ; Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Building 421, Translational Research Center, Philadelphia, PA 19104-5158, USA.; Division of Translational Medicine and Human Genetics, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Building 421, Translational Research Center, Philadelphia, PA 19104-5158, USA.
Reilly MP; Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Building 421, Translational Research Center, Philadelphia, PA 19104-5158, USA.; Division of Translational Medicine and Human Genetics, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, Building 421, Translational Research Center, Philadelphia, PA 19104-5158, USA.
Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave., Boston MA 02215, USA.; Harvard Medical School, Boston MA 02115, USA.
Rivadeneira F; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging NCHA), Leiden, The Netherlands.
Rudan I; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, United Kingdom.
Ruokonen A; Department of Clinical Sciences/Clinical Chemistry, University of Oulu, Oulu, Finland.
Samani N; National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK.; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, LE3 9QP, UK.
Scharnagl H; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria.
Seeley J; MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda.; School of International Development, University of East Anglia, Norwich NR4 7TJ, United Kingdom.
Silander K; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland.; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland.
Stančáková A; University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland.
Stirrups K; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.
Swift AJ; Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.
Tiret L; INSERM UMRS 937, Pierre and Marie Curie University, Paris, France.
Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging NCHA), Leiden, The Netherlands.
van Pelt LJ; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, The Netherlands.; LifeLines Cohort Study, University of Groningen, University Medical Center Groningen, The Netherlands.
Vedantam S; Broad Institute, Program in Medical and Population Genetics, Cambridge, Massachusetts 02142, USA.; Division of Endocrinology, Children's Hospital Boston, Massachusetts 02115, USA.; Division of Genetics, Program in Genomics, Children's Hospital, Boston, Massachusetts 02115, USA.
Wainwright N; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Wijmenga C; LifeLines Cohort Study, University of Groningen, University Medical Center Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, The Netherlands.
Wild SH; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, United Kingdom.
Willemsen G; Department of Biological Psychology, VU Univ, Amsterdam, The Netherlands.
Wilsgaard T; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Wilson JF; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, United Kingdom.
Young EH; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Zhao JH; MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, United Kingdom.
Adair LS; Department of Nutrition, University of North Carolina, Chapel Hill, NC, USA.
Arveiler D; Department of Epidemiology and Public Health, EA 3430, University of Strasbourg, Faculty of Medicine, Strasbourg, France.
Assimes TL; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.
Bennett F; Chemical Pathology, Department of Pathology, University of the West Indies, Mona, Kingston 7, Jamaica.
Bochud M; Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Route de la Corniche 10, 1010 Lausanne, Switzerland.
Boehm BO; Division of Endocrinology and Diabetes, Department of Internal Medicine, Ulm University Medical Centre, Ulm, Germany.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Boomsma DI; Department of Biological Psychology, VU Univ, Amsterdam, The Netherlands.
Borecki IB; Department of Genetics, Washington University School of Medicine, USA.
Bornstein SR; Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, 01307 Dresden, Germany.
Bovet P; Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Route de la Corniche 10, 1010 Lausanne, Switzerland.; Ministry of Health, Victoria, Republic of Seychelles.
Burnier M; Service of Nephrology, Lausanne University Hospital, Lausanne, Switzerland.
Campbell H; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, United Kingdom.
Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Ealing Hospital, Southall, Middlesex UB1 3HW, United Kingdom.; Imperial College Healthcare NHS Trust, London, United Kingdom.
Chen YI; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Department of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Collins FS; Genome Technology Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.
Cooper RS; Department of Preventive Medicine and Epidemiology, Loyola University Medical School, Maywood, Illinois 60153, USA.
Danesh J; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Dedoussis G; Department of Dietetics-Nutrition, Harokopio University, 70 El. Venizelou Str, Athens, Greece.
de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Feranil AB; Office of Population Studies Foundation, University of San Carlos, Talamban, Cebu City, Philippines.
Ferrières J; Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse, France.
Ferrucci L; Clinical Research Branch, National Institute Health, Baltimore, MD, USA.
Freimer NB; Center for Neurobehavioral Genetics, The Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.; Department of Psychiatry, University of California, Los Angeles, USA.
Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.
Groop LC; Department of Clinical Sciences, Lund University, SE-20502, Malmö, Sweden.; Department of Medicine, Helsinki University Hospital, FI-00029 Helsinki, Finland.
Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.
Gyllensten U; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Hamsten A; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Harris TB; Laboratory of Epidemiology, Demography, and Biometry, National Institute on Ageing, Bethesda, MD, USA.
Hingorani A; Genetic Epidemiology Group, Deparment of Epidemiology and Public Health, UCL, London WC1E 6BT, United Kingdom.
Hirschhorn JN; Broad Institute, Program in Medical and Population Genetics, Cambridge, Massachusetts 02142, USA.; Division of Endocrinology, Children's Hospital Boston, Massachusetts 02115, USA.; Division of Genetics, Program in Genomics, Children's Hospital, Boston, Massachusetts 02115, USA.
Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging NCHA), Leiden, The Netherlands.
Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Hsiung CA; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Humphries SE; Cardiovascular Genetics, BHF Laboratories, Institute Cardiovascular Science, University College London, London, United Kingdom.
Hunt SC; Cardiovascular Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.
Iribarren C; Kaiser Permanente, Division of Research, Oakland, CA, USA.
Järvelin MR; Biocenter Oulu, University of Oulu, Oulu, Finland.; Institute of Health Sciences, University of Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, UK.; National Institute for Health and Welfare, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.
Jula A; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland.
Kähönen M; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere 33014, Finland.
Kaprio J; Hjelt Institute, Department of Public Health, University of Helsinki, Finland.; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland.; Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland.
Kesäniemi A; Institute of Clinical Medicine, Department of Medicine, University of Oulu and Clinical Research Center, Oulu University Hospital, Oulu, Finland.
Kivimaki M; Genetic Epidemiology Group, Deparment of Epidemiology and Public Health, UCL, London WC1E 6BT, United Kingdom.
Kooner JS; Ealing Hospital, Southall, Middlesex UB1 3HW, United Kingdom.; Imperial College Healthcare NHS Trust, London, United Kingdom.; National Heart & Lung Institute, Imperial College London, Hammersmith Hospital, London, United Kingdom.
Koudstaal PJ; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.
Krauss RM; Children's Hospital Oakland Research Institute, 5700 Martin Luther King Junior Way, Oakland, CA 94609, USA.
Kuh D; MRC Unit for Lifelong Health and Ageing, 33 Bedford Place, London, WC1B 5JU, United Kingdom.
Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland.
Kyvik KO; Institute of Regional Health Services Research, University of Southern Denmark, Odense, Denmark.; Odense Patient data Explorative Network (OPEN), Odense University Hospital, Odense, Denmark.
Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland.
Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Finland.
Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, United Kingdom.
Martin NG; Queensland Institute of Medical Research, Locked Bag 2000, Royal Brisbane Hospital, Queensland 4029, Australia.
März W; Mannheim Institute of Public Health, Social and Preventive Medicine, Medical Faculty of Mannheim, University of Heidelberg, Ludolf-Krehl-Strasse 7-11, 68167 Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria.; Synlab Academy, Synlab Services GmbH,Gottlieb-Daimler-Straße 25, 68165 Mannheim, Germany.
McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, OX3 7LJ, United Kingdom.
McKenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Kingston 7, Jamaica.
Meneton P; U872 Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, 75006 Paris, France.
Metspalu A; Estonian Genome Center of the University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Moilanen L; Department of Medicine, Kuopio University Hospital, Kuopio, Finland.
Morris AD; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School. Dundee, DD1 9SY, United Kingdom.
Munroe PB; Genome Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Clinical Pharmacology, NIHR Cardiovascular Biomedical Research Unit, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry Queen Mary University of London, London, UK.
Njølstad I; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Power C; Centre For Paediatric Epidemiology and Biostatistics/MRC Centre of Epidemiology for Child Health, University College of London Institute of Child Health, London, United Kingdom.
Pramstaller PP; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany.; Department of Neurology, General Central Hospital, Bolzano, Italy.; Department of Neurology, University of Lübeck, Lübeck, Germany.
Price JF; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, United Kingdom.
Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA.; Group Health Research Institute, Group Health Cooperative, Seattle, WA, USA.
Quertermous T; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.
Saleheen D; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; Center for Non-Communicable Diseases, Karachi, Pakistan.; Department of Medicine, University of Pennsylvania, USA.
Salomaa V; Unit of Chronic Disease Epidemiology and Prevention, National Institute for Health and Welfare, Helsinki, Finland.
Sanghera DK; Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Saramies J; South Karelia Central Hospital, Lappeenranta, Finland.
Schwarz PEH; Department of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, 01307 Dresden, Germany.; Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), Dresden, Germany.
Sheu WH; Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Shuldiner AR; Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland, School of Medicine, Baltimore, Maryland.; Geriatric Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore, Maryland.
Siegbahn A; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Stefansson K; deCODE Genetics/Amgen, 101 Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavík, Iceland.
Strachan DP; Division of Population Health Sciences and Education, St George's, University of London, Cranmer Terrace, London SW17 0RE, United Kingdom.
Tayo BO; Department of Preventive Medicine and Epidemiology, Loyola University Medical School, Maywood, Illinois 60153, USA.
Tremoli E; Department of Pharmacological Sciences, University of Milan, Monzino Cardiology Center, IRCCS, Milan, Italy.
Tuomilehto J; Diabetes Prevention Unit, National Institute for Health and Welfare, 00271 Helsinki, Finland.; Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria.; King Abdulaziz University, Faculty of Medicine, Jeddah 21589, Saudi Arabia.; Red RECAVA Grupo RD06/0014/0015, Hospital Universitario La Paz, 28046.
Uusitupa M; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.; Research Unit, Kuopio University Hospital, Kuopio, Finland.
van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Centre for Medical Systems Biology, Leiden, the Netherlands.
Vollenweider P; Department of Medicine, Lausanne University Hospital, Switzerland.
Wallentin L; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, United Kingdom.
Whitfield JB; Queensland Institute of Medical Research, Locked Bag 2000, Royal Brisbane Hospital, Queensland 4029, Australia.
Wolffenbuttel BHR; LifeLines Cohort Study, University of Groningen, University Medical Center Groningen, The Netherlands.; Department of Endocrinology, University of Groningen, University Medical Center Groningen, The Netherlands.
Ordovas JM; Department of Cardiovascular Epidemiology and Population Genetics, National Center for rdiovascular Investigation, Madrid, Spain.; IMDEA-Alimentacion, Madrid, Spain.; Nutrition and Genomics Laboratory, Jean Mayer-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA.
Boerwinkle E; Human Genetics Center, University of Texas Health Science Center - School of Public Health, Houston, TX 77030, USA.
Palmer CNA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School. Dundee, DD1 9SY, United Kingdom.
Thorsteinsdottir U; deCODE Genetics/Amgen, 101 Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavík, Iceland.
Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave., Boston MA 02215, USA.; Harvard Medical School, Boston MA 02115, USA.
Rotter JI; Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Franks PW; Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Scania University Hosptial, Malmö, Sweden.; Department of Public Health and Primary Care, Unit of Medicine, Umeå University, Umeå, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.
Ripatti S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland.; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland.
Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.; Framingham Heart Study, Framingham, MA, USA.
Sandhu MS; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA.
Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
Deloukas P; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, United Kingdom.
Kathiresan S; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Broad Institute, Program in Medical and Population Genetics, Cambridge, Massachusetts 02142, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA.
Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 USA.
Ingelsson E; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden.; Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, United Kingdom.
Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Pokaż więcej
Corporate Authors:: Global Lipids Genetics Consortium
Źródło:: Nature genetics [Nat Genet] 2013 Nov; Vol. 45 (11), pp. 1274-1283. Date of Electronic Publication: 2013 Oct 06.
Typ publikacji:: Journal Article
MeSH Terms:: Coronary Artery Disease/*blood
Coronary Artery Disease/*genetics
Lipids/*blood
Lipids/*genetics
Asian People/genetics ; Black People/genetics ; Cholesterol, HDL/blood ; Cholesterol, HDL/genetics ; Cholesterol, LDL/blood ; Cholesterol, LDL/genetics ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Genotype ; Humans ; Triglycerides/blood ; Triglycerides/genetics ; White People/genetics

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Tytuł:: Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.
Autorzy:: Ferreira RC; Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.
Freitag DF
Cutler AJ
Howson JM
Rainbow DB
Smyth DJ
Kaptoge S
Clarke P
Boreham C
Coulson RM
Pekalski ML
Chen WM
Onengut-Gumuscu S
Rich SS
Butterworth AS
Malarstig A
Danesh J
Todd JA; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2013 Apr; Vol. 9 (4), pp. e1003444. Date of Electronic Publication: 2013 Apr 04.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Association Studies*
Inflammation*/blood
Inflammation*/genetics
Inflammation*/metabolism
Protein Isoforms*/blood
Protein Isoforms*/genetics
Protein Isoforms*/metabolism
Receptors, Interleukin-6*/blood
Receptors, Interleukin-6*/genetics
Receptors, Interleukin-6*/metabolism
Alleles ; Amino Acid Substitution/genetics ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/genetics ; Humans ; Leukocytes, Mononuclear/metabolism ; Mutation ; Phosphorylation ; Risk Factors ; Signal Transduction

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