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    Wyświetlanie 1-19 z 19
    Tytuł:
    Activation of platelet-rich plasma by pulse electric fields: Voltage, pulse width and calcium concentration can be used to control and tune the release of growth factors, serotonin and hemoglobin.
    Autorzy:
    Neculaes B; GE Research, Niskayuna, NY, United States of America.
    Frelinger AL 3rd; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, United States of America.
    Gerrits AJ; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, United States of America.
    Gremmel T; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, United States of America.; Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.; Department of Internal Medicine I, Cardiology and Intensive Care Medicine, Landesklinikum Mistelbach-Gaenserndorf, Mistelbach, Austria.
    Forde EE; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, United States of America.
    Klopman S; GE Research, Niskayuna, NY, United States of America.
    Carmichael SL; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, United States of America.
    Michelson AD; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, United States of America.
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    Źródło:
    PloS one [PLoS One] 2021 Apr 23; Vol. 16 (4), pp. e0249209. Date of Electronic Publication: 2021 Apr 23 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Electricity*
    Epidermal Growth Factor/*analysis
    Hemoglobins/*analysis
    Platelet-Derived Growth Factor/*analysis
    Platelet-Rich Plasma/*metabolism
    Serotonin/*analysis
    Blood Cell Count ; Calcium/chemistry ; Calcium/pharmacology ; Enzyme-Linked Immunosorbent Assay ; Epidermal Growth Factor/metabolism ; Hemoglobins/metabolism ; Humans ; Platelet Activation/drug effects ; Platelet-Derived Growth Factor/metabolism ; Serotonin/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Platelet count and disease - editorial policy.
    Autorzy:
    Harrison P; Institute for Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
    Lordkipanidzé M; Faculty of Pharmacy, Université De Montréal, Montréal, Canada.; Research Center, Montreal Heart Institute, Montréal, Canada.
    Frelinger AL 3rd; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.
    Thomas MR; Institute for Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
    Watson SP; Institute for Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
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    Źródło:
    Platelets [Platelets] 2020 Nov 16; Vol. 31 (8), pp. 969-970. Date of Electronic Publication: 2020 Aug 07.
    Typ publikacji:
    Editorial
    Opinia redakcyjna
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Platelet surface marker analysis by mass cytometry.
    Autorzy:
    Blair TA; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School , Boston, MA, USA.
    Frelinger AL 3rd; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School , Boston, MA, USA.
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    Źródło:
    Platelets [Platelets] 2020 Jul 03; Vol. 31 (5), pp. 633-640. Date of Electronic Publication: 2019 Sep 22.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Blood Platelets/*metabolism
    Flow Cytometry/*methods
    Blood Platelets/cytology ; Humans
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Publisher Correction: GLS-409, an Antagonist of Both P2Y 1 and P2Y 12 , Potently Inhibits Canine Coronary Artery Thrombosis and Reversibly Inhibits Human Platelet Activation.
    Autorzy:
    Smolensky Koganov E; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.
    Michelson AD; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.
    Yanachkov IB; GLSynthesis Inc., Worcester, MA, USA.
    Yanachkova MI; GLSynthesis Inc., Worcester, MA, USA.
    Wright GE; GLSynthesis Inc., Worcester, MA, USA.
    Przyklenk K; Cardiovascular Research Institute and Departments of Physiology and Emergency Medicine, Wayne State University School of Medicine, Detroit, MI, USA.
    Frelinger AL 3rd; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA. Andrew.Frelinger@childrens.harvard.edu.
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    Źródło:
    Scientific reports [Sci Rep] 2018 Nov 29; Vol. 8 (1), pp. 17580. Date of Electronic Publication: 2018 Nov 29.
    Typ publikacji:
    Published Erratum
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Using flow cytometry to monitor glycoprotein IIb-IIIa activation.
    Autorzy:
    Frelinger AL 3rd; a Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center , Harvard Medical School , Boston , MA , USA.
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    Źródło:
    Platelets [Platelets] 2018 Nov; Vol. 29 (7), pp. 670-676. Date of Electronic Publication: 2018 May 25.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Flow Cytometry*/methods
    Platelet Activation*
    Blood Platelets/*metabolism
    Integrin beta3/*metabolism
    Biomarkers ; Humans
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    GLS-409, an Antagonist of Both P2Y 1 and P2Y 12 , Potently Inhibits Canine Coronary Artery Thrombosis and Reversibly Inhibits Human Platelet Activation.
    Autorzy:
    Smolensky Koganov E; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.
    Michelson AD; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.
    Yanachkov IB; GLSynthesis Inc., Worcester, MA, USA.
    Yanachkova MI; GLSynthesis Inc., Worcester, MA, USA.
    Wright GE; GLSynthesis Inc., Worcester, MA, USA.
    Przyklenk K; Cardiovascular Research Institute and Departments of Physiology and Emergency Medicine, Wayne State University School of Medicine, Detroit, MI, USA.
    Frelinger AL 3rd; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA. Andrew.Frelinger@childrens.harvard.edu.
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    Źródło:
    Scientific reports [Sci Rep] 2018 Sep 28; Vol. 8 (1), pp. 14529. Date of Electronic Publication: 2018 Sep 28.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Coronary Thrombosis/*veterinary
    Dinucleoside Phosphates/*therapeutic use
    Dog Diseases/*drug therapy
    Platelet Activation/*drug effects
    Purinergic P2Y Receptor Antagonists/*therapeutic use
    Animals ; Coronary Thrombosis/drug therapy ; Coronary Thrombosis/metabolism ; Dog Diseases/metabolism ; Dogs ; Female ; Humans ; Platelet Aggregation Inhibitors/therapeutic use ; Receptors, Purinergic P2Y1/metabolism ; Receptors, Purinergic P2Y12/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Tunable activation of therapeutic platelet-rich plasma by pulse electric field: Differential effects on clot formation, growth factor release, and platelet morphology.
    Autorzy:
    Frelinger AL 3rd; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, United States of America.
    Gerrits AJ; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, United States of America.
    Neculaes VB; GE Global Research Center, Niskayuna, New York, United States of America.
    Gremmel T; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, United States of America.; Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
    Torres AS; GE Global Research Center, Niskayuna, New York, United States of America.
    Caiafa A; GE Global Research Center, Niskayuna, New York, United States of America.
    Carmichael SL; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, United States of America.
    Michelson AD; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, United States of America.
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    Źródło:
    PloS one [PLoS One] 2018 Sep 26; Vol. 13 (9), pp. e0203557. Date of Electronic Publication: 2018 Sep 26 (Print Publication: 2018).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Intercellular Signaling Peptides and Proteins/*metabolism
    Platelet Activation/*physiology
    Platelet-Rich Plasma/*metabolism
    Electrochemical Techniques ; Enzyme-Linked Immunosorbent Assay ; Epidermal Growth Factor/metabolism ; Healthy Volunteers ; Humans ; Microscopy, Electron, Transmission ; P-Selectin/metabolism ; Platelet-Derived Growth Factor/metabolism ; Thrombelastography ; Toll-Like Receptor 9/metabolism ; Vascular Endothelial Growth Factor A/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Modification of Pulsed Electric Field Conditions Results in Distinct Activation Profiles of Platelet-Rich Plasma.
    Autorzy:
    Frelinger AL 3rd; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
    Gerrits AJ; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
    Garner AL; School of Nuclear Engineering, Purdue University, West Lafayette, Indiana, United States of America.
    Torres AS; GE Global Research Center, Niskayuna, New York, United States of America.
    Caiafa A; GE Global Research Center, Niskayuna, New York, United States of America.
    Morton CA; GE Global Research Center, Niskayuna, New York, United States of America.
    Berny-Lang MA; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
    Carmichael SL; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
    Neculaes VB; GE Global Research Center, Niskayuna, New York, United States of America.
    Michelson AD; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
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    Źródło:
    PloS one [PLoS One] 2016 Aug 24; Vol. 11 (8), pp. e0160933. Date of Electronic Publication: 2016 Aug 24 (Print Publication: 2016).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Platelet Activation*
    Platelet-Rich Plasma*
    Pulsed Radiofrequency Treatment*
    Biomarkers ; Blood Coagulation ; Blood Platelets/metabolism ; Cell Line ; Cell Proliferation ; Cell-Derived Microparticles/metabolism ; Humans ; Immunophenotyping ; Intercellular Signaling Peptides and Proteins/metabolism ; Phenotype ; Wound Healing
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    In Vivo and protease-activated receptor-1-mediated platelet activation in patients presenting for cardiac catheterization.
    Autorzy:
    Gremmel T; a Division of Hematology/Oncology , Center for Platelet Research Studies, Boston Children´s Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA.; b Department of Internal Medicine II , Medical University of Vienna , Vienna , Austria.
    Michelson AD; a Division of Hematology/Oncology , Center for Platelet Research Studies, Boston Children´s Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA.
    Frelinger AL 3rd; a Division of Hematology/Oncology , Center for Platelet Research Studies, Boston Children´s Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA.
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    Źródło:
    Platelets [Platelets] 2016 Jun; Vol. 27 (4), pp. 308-16. Date of Electronic Publication: 2015 Nov 10.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Platelet Activation*/drug effects
    Blood Platelets/*metabolism
    Cardiac Catheterization/*adverse effects
    Receptor, PAR-1/*metabolism
    Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/metabolism ; Acute Coronary Syndrome/therapy ; Aged ; Biomarkers ; Blood Platelets/drug effects ; Comorbidity ; Coronary Angiography ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/metabolism ; Coronary Artery Disease/therapy ; Female ; Humans ; Male ; Middle Aged ; Monocytes/metabolism ; Odds Ratio ; P-Selectin/metabolism ; Platelet Aggregation/drug effects ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism ; Platelet Membrane Glycoproteins/metabolism ; ROC Curve ; Receptors, Thrombin/therapeutic use
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Platelet-rich plasma stimulated by pulse electric fields: Platelet activation, procoagulant markers, growth factor release and cell proliferation.
    Autorzy:
    Frelinger AL 3rd; a Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA and.
    Torres AS; b GE Global Research Center , Niskayuna , NY , USA.
    Caiafa A; b GE Global Research Center , Niskayuna , NY , USA.
    Morton CA; b GE Global Research Center , Niskayuna , NY , USA.
    Berny-Lang MA; a Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA and.
    Gerrits AJ; a Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA and.
    Carmichael SL; a Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA and.
    Neculaes VB; b GE Global Research Center , Niskayuna , NY , USA.
    Michelson AD; a Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA and.
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    Źródło:
    Platelets [Platelets] 2016; Vol. 27 (2), pp. 128-35. Date of Electronic Publication: 2015 Jun 01.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Electricity*
    Epidermal Growth Factor/*metabolism
    Platelet-Rich Plasma/*cytology
    Animals ; Annexin A5/biosynthesis ; Annexin A5/genetics ; Blood Platelets/cytology ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Cattle ; Cell Line ; Cell Proliferation/drug effects ; Cell-Derived Microparticles/metabolism ; Electric Stimulation ; Epidermal Growth Factor/biosynthesis ; Epidermal Growth Factor/genetics ; Epithelial Cells/cytology ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Flow Cytometry ; Gene Expression ; Humans ; Octoxynol/pharmacology ; P-Selectin/biosynthesis ; P-Selectin/genetics ; Platelet Activation/drug effects ; Platelet-Rich Plasma/metabolism ; Receptors, Thrombin/chemistry ; Thrombin/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Aspirin response: Differences in serum thromboxane B2 levels between clinical studies.
    Autorzy:
    Brun C; a Division of General Internal Medicine , Geneva University Hospitals , Geneva , Switzerland .; b Geneva Platelet Group, University of Geneva School of Medicine , Geneva , Switzerland .
    Daali Y; b Geneva Platelet Group, University of Geneva School of Medicine , Geneva , Switzerland .; c Division of Clinical Pharmacology , Geneva University Hospitals , Geneva , Switzerland .
    Combescure C; d Division of Clinical Epidemiology , Geneva University Hospitals , Geneva , Switzerland .
    Zufferey A; b Geneva Platelet Group, University of Geneva School of Medicine , Geneva , Switzerland .
    Michelson AD; e Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA .
    Fontana P; b Geneva Platelet Group, University of Geneva School of Medicine , Geneva , Switzerland .; f Division of Angiology and Haemostasis , Geneva University Hospitals , Geneva , Switzerland , and.
    Reny JL; b Geneva Platelet Group, University of Geneva School of Medicine , Geneva , Switzerland .; g Division of Internal Medicine and Rehabilitation, Trois-Chêne, Department of Internal Medicine, Rehabilitation and Geriatrics , Geneva University Hospitals , Geneva , Switzerland.
    Frelinger AL 3rd; e Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA .
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    Źródło:
    Platelets [Platelets] 2016; Vol. 27 (3), pp. 196-202. Date of Electronic Publication: 2015 Aug 13.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Aspirin/*pharmacology
    Platelet Aggregation Inhibitors/*pharmacology
    Thromboxane B2/*blood
    Aged ; Aspirin/therapeutic use ; Biomarkers ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/drug therapy ; Chromatography, Liquid ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Male ; Middle Aged ; Platelet Aggregation Inhibitors/therapeutic use ; Tandem Mass Spectrometry ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Soluble CD40 Ligand in Aspirin-Treated Patients Undergoing Cardiac Catheterization.
    Autorzy:
    Gremmel T; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children´s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America; Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
    Frelinger AL 3rd; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children´s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
    Michelson AD; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children´s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
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    Źródło:
    PloS one [PLoS One] 2015 Aug 03; Vol. 10 (8), pp. e0134599. Date of Electronic Publication: 2015 Aug 03 (Print Publication: 2015).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cardiac Catheterization*
    Aspirin/*therapeutic use
    CD40 Ligand/*blood
    Cardiovascular Diseases/*blood
    Platelet Aggregation Inhibitors/*therapeutic use
    Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/drug therapy ; Clopidogrel ; Female ; Humans ; Male ; Middle Aged ; Ticlopidine/analogs & derivatives ; Ticlopidine/therapeutic use
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Do immature platelet levels in chest pain patients presenting to the emergency department aid in the diagnosis of acute coronary syndrome?
    Autorzy:
    Berny-Lang MA; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
    Darling CE
    Frelinger AL 3rd
    Barnard MR
    Smith CS
    Michelson AD
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    Źródło:
    International journal of laboratory hematology [Int J Lab Hematol] 2015 Feb; Vol. 37 (1), pp. 112-9. Date of Electronic Publication: 2014 May 08.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Emergency Service, Hospital*
    Platelet Count*
    Acute Coronary Syndrome/*blood
    Acute Coronary Syndrome/*diagnosis
    Blood Platelets/*cytology
    Chest Pain/*diagnosis
    Chest Pain/*etiology
    Aged ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Risk Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The effect of prasugrel on ADP-stimulated markers of platelet activation in patients with sickle cell disease.
    Autorzy:
    Jakubowski JA; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis , IN , USA .
    Zhou C
    Winters KJ
    Lachno DR
    Howard J
    Payne CD
    Mant T
    Jurcevic S
    Frelinger AL 3rd
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    Źródło:
    Platelets [Platelets] 2015; Vol. 26 (5), pp. 474-9. Date of Electronic Publication: 2014 Aug 20.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Adenosine Diphosphate/*metabolism
    Anemia, Sickle Cell/*blood
    Anemia, Sickle Cell/*drug therapy
    Blood Platelets/*drug effects
    Blood Platelets/*metabolism
    Platelet Activation/*drug effects
    Platelet Aggregation Inhibitors/*therapeutic use
    Prasugrel Hydrochloride/*therapeutic use
    Adenosine Diphosphate/pharmacology ; Adult ; Biomarkers ; Case-Control Studies ; Female ; Humans ; Leukocytes/drug effects ; Leukocytes/metabolism ; Male ; Middle Aged ; Platelet Aggregation Inhibitors/pharmacology ; Prasugrel Hydrochloride/pharmacology ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Antiplatelet activity, P2Y₁ and P2Y₁₂ inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'″-P¹ ,P⁴-dithio-P²,P³-chloromethylenetetraphosphate.
    Autorzy:
    Chang H; Center for Platelet Function Studies, Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America; Hematology Division, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan.
    Yanachkov IB; GLSynthesis Inc., Worcester, Massachusetts, United States of America.
    Dix EJ; GLSynthesis Inc., Worcester, Massachusetts, United States of America.
    Yanachkova M; GLSynthesis Inc., Worcester, Massachusetts, United States of America.
    Li Y; Center for Platelet Function Studies, Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
    Barnard MR; Center for Platelet Function Studies, Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
    Wright GE; GLSynthesis Inc., Worcester, Massachusetts, United States of America.
    Michelson AD; Center for Platelet Function Studies, Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
    Frelinger AL 3rd; Center for Platelet Function Studies, Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
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    Źródło:
    PloS one [PLoS One] 2014 Apr 10; Vol. 9 (4), pp. e94780. Date of Electronic Publication: 2014 Apr 10 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Dinucleoside Phosphates/*pharmacology
    Platelet Aggregation/*drug effects
    Purinergic P2Y Receptor Antagonists/*pharmacology
    Receptors, Purinergic P2Y1/*metabolism
    Dinucleoside Phosphates/pharmacokinetics ; Humans ; Platelet Function Tests ; Purinergic P2Y Receptor Antagonists/pharmacokinetics ; Stereoisomerism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Platelet activation and inhibition in sickle cell disease (pains) study.
    Autorzy:
    Frelinger AL 3rd; Center for Platelet Research Studies, Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School , Boston, MA , USA.
    Jakubowski JA
    Brooks JK
    Carmichael SL
    Berny-Lang MA
    Barnard MR
    Heeney MM
    Michelson AD
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    Źródło:
    Platelets [Platelets] 2014; Vol. 25 (1), pp. 27-35. Date of Electronic Publication: 2013 Mar 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Anemia, Sickle Cell/*blood
    Blood Platelets/*drug effects
    Piperazines/*administration & dosage
    Platelet Activation/*drug effects
    Platelet Aggregation/*drug effects
    Purinergic P2Y Receptor Antagonists/*administration & dosage
    Adenosine Diphosphate/blood ; Adolescent ; Adult ; Anemia, Sickle Cell/drug therapy ; Blood Platelets/metabolism ; Case-Control Studies ; Female ; Humans ; Male ; Platelet Aggregation Inhibitors/metabolism ; Platelet Aggregation Inhibitors/pharmacology ; Receptors, Purinergic P2Y12/blood
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors.
    Autorzy:
    Scheer FA; Medical Chronobiology Program, Division of Sleep Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America. />Michelson AD
    Frelinger AL 3rd
    Evoniuk H
    Kelly EE
    McCarthy M
    Doamekpor LA
    Barnard MR
    Shea SA
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2011; Vol. 6 (9), pp. e24549. Date of Electronic Publication: 2011 Sep 08.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Circadian Rhythm*
    Platelet Activation*
    Adult ; Behavior ; Blood Pressure ; Body Temperature ; Cardiovascular System ; Exercise ; Female ; Humans ; Light ; Male ; Stress, Psychological ; Temperature ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Nephropathy in type 1 diabetes is associated with increased circulating activated platelets and platelet hyperreactivity.
    Autorzy:
    Tarnow I; Department of Small Animal Clinical Science, Faculty of Life Sciences, University of Copenhagen, Frederiksberg C, Denmark. />Michelson AD
    Barnard MR
    Frelinger AL 3rd
    Aasted B
    Jensen BR
    Parving HH
    Rossing P
    Tarnow L
    Pokaż więcej
    Źródło:
    Platelets [Platelets] 2009 Nov; Vol. 20 (7), pp. 513-9.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Blood Platelets/*physiology
    Diabetes Mellitus, Type 1/*blood
    Diabetic Nephropathies/*blood
    Case-Control Studies ; Female ; Flow Cytometry ; Humans ; Male ; Middle Aged ; Platelet Activation/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation.
    Autorzy:
    Loftus JC; Committee on Vascular Biology, Research Institute of Scripps Clinic, La Jolla, CA 92037.
    O'Toole TE
    Plow EF
    Glass A
    Frelinger AL 3rd
    Ginsberg MH
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 1990 Aug 24; Vol. 249 (4971), pp. 915-8.
    Typ publikacji:
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Mutation*
    Integrins/*genetics
    Platelet Membrane Glycoproteins/*genetics
    Amino Acid Sequence ; Animals ; Aspartic Acid ; Base Sequence ; Binding Sites ; Cell Line ; Integrins/metabolism ; Ligands ; Macromolecular Substances ; Molecular Sequence Data ; Oligonucleotide Probes ; Platelet Membrane Glycoproteins/metabolism ; Polymerase Chain Reaction ; Protein Conformation ; Sequence Homology, Nucleic Acid ; Tyrosine
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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