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Wyszukujesz frazę ""Fructose"" wg kryterium: Temat


Tytuł :
KHK inhibition for the treatment of hereditary fructose intolerance and nonalcoholic fatty liver disease: a double-edged sword.
Autorzy :
Pinheiro FC; Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul RS, Brazil. .; BRAIN Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil. .; Federal University of Pampa (Unipampa), Itaqui, RS, Brazil. .; Medical Genetic Service, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 350, Porto Alegre, RS, 90035-903, Brazil. .
Sperb-Ludwig F; Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul RS, Brazil.; BRAIN Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Schwartz IVD; Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul RS, Brazil.; BRAIN Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.; Genetics Department, Biosciences Institute, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.; Medical Genetics Department, HCPA, Porto Alegre, RS, Brazil.
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Sep; Vol. 77 (17), pp. 3465-3466. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Fructose Intolerance*
Non-alcoholic Fatty Liver Disease*
Fructose ; Humans
Czasopismo naukowe
Tytuł :
Fructose-Induced Intestinal Microbiota Shift Following Two Types of Short-Term High-Fructose Dietary Phases.
Autorzy :
Beisner J; Institute of Nutritional Medicine, University of Hohenheim, Fruwirthstr. 12, 70599 Stuttgart, Germany.
Gonzalez-Granda A; Institute of Nutritional Medicine, University of Hohenheim, Fruwirthstr. 12, 70599 Stuttgart, Germany.
Basrai M; Institute of Nutritional Medicine, University of Hohenheim, Fruwirthstr. 12, 70599 Stuttgart, Germany.
Damms-Machado A; Institute of Nutritional Medicine, University of Hohenheim, Fruwirthstr. 12, 70599 Stuttgart, Germany.
Bischoff SC; Institute of Nutritional Medicine, University of Hohenheim, Fruwirthstr. 12, 70599 Stuttgart, Germany.
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Źródło :
Nutrients [Nutrients] 2020 Nov 10; Vol. 12 (11). Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Dietary Supplements*
Feces/*microbiology
Fructose/*administration & dosage
Gastrointestinal Microbiome/*physiology
RNA, Ribosomal, 16S/*genetics
Adult ; Animals ; Bacteroidetes/growth & development ; Diet, Carbohydrate-Restricted ; Female ; Firmicutes/growth & development ; Fruit ; Healthy Volunteers ; High Fructose Corn Syrup/administration & dosage ; Humans ; Pilot Projects ; Young Adult
Czasopismo naukowe
Tytuł :
Pitfalls in the Diagnosis of Hereditary Fructose Intolerance.
Autorzy :
Kim AY; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and .
Hughes JJ; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Pipitone Dempsey A; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and.
Sondergaard Schatz K; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and.
Wang T; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and.
Gunay-Aygun M; Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland; and.
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Źródło :
Pediatrics [Pediatrics] 2020 Aug; Vol. 146 (2).
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Fructose Intolerance/*diagnosis
Adult ; Aged ; Asymptomatic Diseases ; Child ; Child, Preschool ; Developmental Disabilities/genetics ; Direct-To-Consumer Screening and Testing ; Dwarfism/genetics ; Failure to Thrive/genetics ; Female ; Food Preferences ; Fructose Intolerance/genetics ; Fructose-Bisphosphate Aldolase/genetics ; Fruit/adverse effects ; Genetic Testing ; Humans ; Incidental Findings ; Infertility, Female ; Male ; Preconception Care ; Vegetables/adverse effects ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
The antitumor role of a newly discovered α-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
Autorzy :
Wang J; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China.
Li Z; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China.
Yang X; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China.
Qiao Y; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China.
Feng C; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China.
Yu S; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China.
Jing H; Department of Pharmacology and Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, School of Pharmacy, Fourth Military Medical University, Xi'an, China; School of Pharmacy, Xi'an Medical University, Xi'an, China.
Liu W; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China.
Ren L; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China.
Duan Q; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China. Electronic address: .
Li XQ; Department of Pharmacology and Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, School of Pharmacy, Fourth Military Medical University, Xi'an, China.
Cao W; Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling, 712100, China; Department of Pharmacology and Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, School of Pharmacy, Fourth Military Medical University, Xi'an, China. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Mar 01; Vol. 255, pp. 117532. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Coleoptera/*chemistry
Fructose-Bisphosphate Aldolase/*genetics
Gene Expression Regulation, Neoplastic/*drug effects
Glucans/*pharmacology
Liver Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Fructose-Bisphosphate Aldolase/antagonists & inhibitors ; Fructose-Bisphosphate Aldolase/metabolism ; Glucans/chemistry ; Glucans/isolation & purification ; Glycolysis/drug effects ; Glycolysis/genetics ; Hep G2 Cells ; Hexokinase/genetics ; Hexokinase/metabolism ; Humans ; L-Lactate Dehydrogenase/genetics ; L-Lactate Dehydrogenase/metabolism ; Larva/chemistry ; Liver Neoplasms/enzymology ; Liver Neoplasms/genetics ; Liver Neoplasms/pathology ; Mice ; Pyruvate Kinase/genetics ; Pyruvate Kinase/metabolism ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Fructose Induces Fluconazole Resistance in Candida albicans through Activation of Mdr1 and Cdr1 Transporters.
Autorzy :
Suchodolski J; Department of Biotransformation, Faculty of Biotechnology, University of Wrocław, 50-383 Wrocław, Poland.
Krasowska A; Department of Biotransformation, Faculty of Biotechnology, University of Wrocław, 50-383 Wrocław, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 21; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 21.
Typ publikacji :
Journal Article
MeSH Terms :
Candida albicans/*drug effects
Drug Resistance, Fungal/*drug effects
Fluconazole/*pharmacology
Fructose/*pharmacology
Fungal Proteins/*metabolism
Membrane Transport Proteins/*metabolism
Candida albicans/cytology ; Carbon/pharmacology ; Cell Proliferation/drug effects ; Drug Resistance, Multiple/drug effects ; Fructose/blood ; Green Fluorescent Proteins/metabolism ; Subcellular Fractions/metabolism
Czasopismo naukowe
Tytuł :
Diagnostic Utility of Carbohydrate Breath Tests for SIBO, Fructose, and Lactose Intolerance.
Autorzy :
Amieva-Balmori M; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.; Universidad Veracruzana, Veracruz, Mexico.
Coss-Adame E; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.; Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico.
Rao NS; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.
Dávalos-Pantoja BM; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.
Rao SSC; Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA. .
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Źródło :
Digestive diseases and sciences [Dig Dis Sci] 2020 May; Vol. 65 (5), pp. 1405-1413. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Blind Loop Syndrome/*diagnosis
Breath Tests/*methods
Carbohydrates/*analysis
Fructose Metabolism, Inborn Errors/*diagnosis
Lactose Intolerance/*diagnosis
Adult ; Blind Loop Syndrome/epidemiology ; Diagnosis, Differential ; Female ; Fructose/analysis ; Fructose Metabolism, Inborn Errors/epidemiology ; Glucose/analysis ; Humans ; Lactose/analysis ; Lactose Intolerance/epidemiology ; Male ; Middle Aged ; Predictive Value of Tests ; Prevalence
Czasopismo naukowe
Tytuł :
Apolipoprotein A5 controls fructose-induced metabolic dysregulation in mice.
Autorzy :
Ress C; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria; Christan Doppler Laboratory for Metabolic Crosstalk, Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Dobner J; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria; Christan Doppler Laboratory for Metabolic Crosstalk, Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Rufinatscha K; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria; Christan Doppler Laboratory for Metabolic Crosstalk, Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Staels B; Institut Pasteur de Lille, CHU Lille, Univ. Lille - EGID, Lille, France.
Hofer M; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria; Christan Doppler Laboratory for Metabolic Crosstalk, Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Folie S; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria; Christan Doppler Laboratory for Metabolic Crosstalk, Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Radlinger B; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria; Christan Doppler Laboratory for Metabolic Crosstalk, Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Adolph TE; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Rubin EM; Department of Genome Sciences, Lawrence Berkeley National Laboratory, Berkeley and DOE Joint Genome Institute, Walnut Creek, USA.
Roden M; Institute for Clinical Diabetology, German Diabetes Center (DDZ), Heinrich Heine University, Düsseldorf, Germany; German Center for Diabetes Research, München-Neuherberg, Germany; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Tilg H; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Kaser S; Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria; Christan Doppler Laboratory for Metabolic Crosstalk, Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: .
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Źródło :
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2021 Mar 10; Vol. 31 (3), pp. 972-978. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dietary Sugars*
Fructose*
Insulin Resistance*
Apolipoprotein A-V/*deficiency
Blood Glucose/*metabolism
Insulin/*blood
Liver/*metabolism
Non-alcoholic Fatty Liver Disease/*metabolism
Triglycerides/*metabolism
Animals ; Apolipoprotein A-V/genetics ; Biomarkers/blood ; Disease Models, Animal ; Fatty Acids/blood ; Mice, Knockout ; Non-alcoholic Fatty Liver Disease/genetics ; Non-alcoholic Fatty Liver Disease/prevention & control
Czasopismo naukowe
Tytuł :
Cloning, purification and characterisation of cytosolic fructose-1,6-bisphosphatase from mung bean (Vigna radiata).
Autorzy :
Chen L; Department of Food Science and Technology, National University of Singapore, Singapore 117542, Singapore; National University of Singapore (Suzhou) Research Institute, 377 Lin Quan Street, Suzhou Industrial Park, Suzhou, Jiangsu 215123, PR China.
Zhao X; Department of Food Science and Technology, National University of Singapore, Singapore 117542, Singapore; National University of Singapore (Suzhou) Research Institute, 377 Lin Quan Street, Suzhou Industrial Park, Suzhou, Jiangsu 215123, PR China.
He Y; Department of Food Science and Technology, National University of Singapore, Singapore 117542, Singapore; National University of Singapore (Suzhou) Research Institute, 377 Lin Quan Street, Suzhou Industrial Park, Suzhou, Jiangsu 215123, PR China.
Yang H; Department of Food Science and Technology, National University of Singapore, Singapore 117542, Singapore; National University of Singapore (Suzhou) Research Institute, 377 Lin Quan Street, Suzhou Industrial Park, Suzhou, Jiangsu 215123, PR China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Jun 15; Vol. 347, pp. 128973. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Cytosol/*enzymology
Fructose-Bisphosphatase/*genetics
Fructose-Bisphosphatase/*isolation & purification
Vigna/*enzymology
Vigna/*genetics
Adenosine Monophosphate/metabolism ; Animals ; Binding Sites ; Cloning, Molecular ; Fructose-Bisphosphatase/chemistry ; Fructose-Bisphosphatase/metabolism ; Kinetics ; Molecular Docking Simulation ; Mutagenesis, Site-Directed ; Vigna/cytology
Czasopismo naukowe
Tytuł :
Recent advances in fructose intake and risk of hyperuricemia.
Autorzy :
Zhang C; Department of Medical Laboratory, Shenzhen Longhua District Central Hospital, Guangdong Medical University, Shenzhen, Guangdong, 518110, PR China.
Li L; Department of Quality Control, Shenzhen Longhua District Central Hospital, Guangdong Medical University, Shenzhen, Guangdong, 518110, PR China.
Zhang Y; Clinical Laboratory, Shenzhen Longhua District Central Hospital, Guangdong Medical University, Shenzhen, Guangdong, 518110, PR China.
Zeng C; Department of Medical Laboratory, Shenzhen Longhua District Central Hospital, Guangdong Medical University, Shenzhen, Guangdong, 518110, PR China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 Nov; Vol. 131, pp. 110795. Date of Electronic Publication: 2020 Sep 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Diet*
Fructose/*adverse effects
Hyperuricemia/*epidemiology
Animals ; Fructose/administration & dosage ; Fructose/metabolism ; Humans ; Risk ; Uric Acid/blood
Czasopismo naukowe
Tytuł :
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
Autorzy :
He X; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences (CAS), Shanghai, China.; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China.
Li M; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences (CAS), Shanghai, China.; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China.
Yu H; The Eastern Hepatobiliary Surgery Hospital, Shanghai, China.
Liu G; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences (CAS), Shanghai, China.; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China.
Wang N; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences (CAS), Shanghai, China.; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China.
Yin C; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Tu Q; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Narla G; Division of Genetic Medicine, Department of International Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
Tao Y; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences (CAS), Shanghai, China.
Cheng S; The Eastern Hepatobiliary Surgery Hospital, Shanghai, China.
Yin H; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences (CAS), Shanghai, China.; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.; Key Laboratory of Food Safety Risk Assessment, Ministry of Health, Beijing, China.
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Źródło :
PLoS biology [PLoS Biol] 2020 Dec 04; Vol. 18 (12), pp. e3000803. Date of Electronic Publication: 2020 Dec 04 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Hepatocellular/*metabolism
Fructose-Bisphosphate Aldolase/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Animals ; Apoptosis/drug effects ; Carcinoma, Hepatocellular/physiopathology ; Cell Line, Tumor ; Cell Survival/genetics ; China ; Fructose-Bisphosphate Aldolase/biosynthesis ; Fructose-Bisphosphate Aldolase/genetics ; Glucose/metabolism ; Humans ; Liver Neoplasms/metabolism ; Male ; Mice ; Mice, Nude ; Phosphorylation ; Protein Phosphatase 2/metabolism ; Protein Phosphatase 2/physiology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
High fructose intake and the route towards cardiometabolic diseases.
Autorzy :
Lelis DF; Postgraduate Program in Health Sciences, Montes Claros State University, Montes Claros, MG 39401-089, Brazil.
Andrade JMO; Postgraduate Program in Health Sciences, Montes Claros State University, Montes Claros, MG 39401-089, Brazil.
Almenara CCP; Department of Physiological Sciences, Federal University of Espírito Santo, Vitória, ES 27042-755, Brazil.
Broseguini-Filho GB; Department of Physiological Sciences, Federal University of Espírito Santo, Vitória, ES 27042-755, Brazil.
Mill JG; Department of Physiological Sciences, Federal University of Espírito Santo, Vitória, ES 27042-755, Brazil.
Baldo MP; Postgraduate Program in Health Sciences, Montes Claros State University, Montes Claros, MG 39401-089, Brazil; Department of Medicine, Centro Universitário UNIFIPMOC, Montes Claros, MG 39408-007, Brazil; Department of Pathophysiology, Montes Claros State University, Montes Claros, MG 39401-089, Brazil. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118235. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cardiovascular Diseases/*etiology
Fructose/*administration & dosage
High Fructose Corn Syrup/*administration & dosage
Animals ; Cardiovascular Diseases/metabolism ; Diet ; Feeding Behavior ; Fructose/adverse effects ; High Fructose Corn Syrup/adverse effects ; Humans ; Quality of Life ; Sweetening Agents/administration & dosage ; Sweetening Agents/adverse effects
Czasopismo naukowe
Tytuł :
Fructose 1,6- bis phosphatase: getting the message across.
Autorzy :
Timson DJ; School of Pharmacy and Biomolecular Sciences, University of Brighton, Huxley Building, Lewes Road, Brighton BN2 4GJ, U.K. .
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Źródło :
Bioscience reports [Biosci Rep] 2019 Mar 06; Vol. 39 (3). Date of Electronic Publication: 2019 Mar 06 (Print Publication: 2019).
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Diabetes Mellitus, Type 2*
Fructose-Bisphosphatase*
Adenosine Monophosphate ; Animals ; Fructose ; Mutation
Czasopismo naukowe
Tytuł :
Constitutive inorganic pyrophosphatase as a reciprocal regulator of three inducible enzymes in Escherichia coli.
Autorzy :
Vorobyeva NN; Department of Chemistry and Belozersky, Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russian Federation.
Kurilova SA; Department of Chemistry and Belozersky, Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russian Federation.
Vlasova AV; Department of Chemistry and Belozersky, Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russian Federation.
Anashkin VA; Department of Chemistry and Belozersky, Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russian Federation.
Nazarova TI; Department of Chemistry and Belozersky, Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russian Federation.
Rodina EV; Department of Chemistry and Belozersky, Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russian Federation.
Baykov AA; Department of Chemistry and Belozersky, Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russian Federation. Electronic address: .
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2021 Jan; Vol. 1865 (1), pp. 129762. Date of Electronic Publication: 2020 Oct 11.
Typ publikacji :
Journal Article
MeSH Terms :
Escherichia coli/*metabolism
Escherichia coli Proteins/*metabolism
Fructose-Bisphosphate Aldolase/*metabolism
Glucose-6-Phosphate Isomerase/*metabolism
Glutamate Decarboxylase/*metabolism
Inorganic Pyrophosphatase/*metabolism
Membrane Proteins/*metabolism
Escherichia coli/chemistry ; Escherichia coli Infections/microbiology ; Escherichia coli Proteins/chemistry ; Fructose-Bisphosphate Aldolase/chemistry ; Glucose-6-Phosphate Isomerase/chemistry ; Glutamate Decarboxylase/chemistry ; Humans ; Inorganic Pyrophosphatase/chemistry ; Kinetics ; Membrane Proteins/chemistry ; Protein Multimerization
Czasopismo naukowe
Tytuł :
High-level expression of Thermobifida fusca glucose isomerase for high fructose corn syrup biosynthesis.
Autorzy :
Zhu F; College of Biology and Pharmaceutical Engineering, Anhui Engineering Laboratory for Conservation and Sustainable Utilization of Traditional Chinese Medicine Resources, West Anhui University, Lu'an City 237012, China.
Deng H; College of Biology and Pharmaceutical Engineering, Anhui Engineering Laboratory for Conservation and Sustainable Utilization of Traditional Chinese Medicine Resources, West Anhui University, Lu'an City 237012, China.
He X; College of Biology and Pharmaceutical Engineering, Anhui Engineering Laboratory for Conservation and Sustainable Utilization of Traditional Chinese Medicine Resources, West Anhui University, Lu'an City 237012, China.
Song X; College of Biology and Pharmaceutical Engineering, Anhui Engineering Laboratory for Conservation and Sustainable Utilization of Traditional Chinese Medicine Resources, West Anhui University, Lu'an City 237012, China.
Chen N; College of Biology and Pharmaceutical Engineering, Anhui Engineering Laboratory for Conservation and Sustainable Utilization of Traditional Chinese Medicine Resources, West Anhui University, Lu'an City 237012, China. Electronic address: .
Wang W; School of Life Sciences, Anhui Agricultural University, Hefei 230036, China. Electronic address: .
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Źródło :
Enzyme and microbial technology [Enzyme Microb Technol] 2020 Apr; Vol. 135, pp. 109494. Date of Electronic Publication: 2019 Dec 13.
Typ publikacji :
Journal Article
MeSH Terms :
Actinobacteria/*enzymology
Aldose-Ketose Isomerases/*metabolism
Bacterial Proteins/*metabolism
High Fructose Corn Syrup/*metabolism
Actinobacteria/genetics ; Aldose-Ketose Isomerases/chemistry ; Aldose-Ketose Isomerases/genetics ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Catalytic Domain ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Fructose/metabolism ; Gene Expression ; Glucose/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
The effect of corn syrup and whey on the conversion process of CO to ethanol using Clostridium ljungdahlii.
Autorzy :
Gunay B; Department of Bioengineering, Faculty of Engineering, Ege University, 35100, Izmir, Turkey.
Azbar N; Department of Bioengineering, Faculty of Engineering, Ege University, 35100, Izmir, Turkey.
Keskin T; Department of Bioengineering, Faculty of Engineering, Ege University, 35100, Izmir, Turkey; Department of Environmental Protection Technologies, Izmir Democracy University, 35140, Izmir, Turkey. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2020 Dec; Vol. 261, pp. 127734. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article
MeSH Terms :
Biofuels/*analysis
Carbon Monoxide/*chemistry
Ethanol/*analysis
High Fructose Corn Syrup/*chemistry
Whey/*chemistry
Carbon Monoxide/metabolism ; Clostridium/metabolism ; Culture Media/metabolism ; Ethanol/metabolism ; Fermentation ; High Fructose Corn Syrup/metabolism ; Powders ; Whey/metabolism
SCR Organism :
Clostridium ljungdahlii
Czasopismo naukowe
Tytuł :
Berberine attenuates fructose-induced insulin resistance by stimulating the hepatic LKB1/AMPK/PGC1α pathway in mice.
Autorzy :
Li Y; Henan Key Laboratory for Modern Research on Zhongjing's Herbal Formulae, Scientific Research and Experiment Center, Henan University of Chinese Medicine, Zhengzhou, Henan, PR China.
Wang B; Henan Key Laboratory for Modern Research on Zhongjing's Herbal Formulae, Scientific Research and Experiment Center, Henan University of Chinese Medicine, Zhengzhou, Henan, PR China.
Shen J; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, PR China.
Bai M; Henan Key Laboratory for Modern Research on Zhongjing's Herbal Formulae, Scientific Research and Experiment Center, Henan University of Chinese Medicine, Zhengzhou, Henan, PR China.
Xu E; Henan Key Laboratory for Modern Research on Zhongjing's Herbal Formulae, Scientific Research and Experiment Center, Henan University of Chinese Medicine, Zhengzhou, Henan, PR China.
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Źródło :
Pharmaceutical biology [Pharm Biol] 2020 Dec; Vol. 58 (1), pp. 385-392.
Typ publikacji :
Journal Article
MeSH Terms :
Berberine/*pharmacology
Fructose/*toxicity
Insulin Resistance/*physiology
Liver/*metabolism
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/*metabolism
Protein Kinases/*metabolism
Protein-Serine-Threonine Kinases/*metabolism
Animals ; Dose-Response Relationship, Drug ; Fructose/antagonists & inhibitors ; Liver/drug effects ; Male ; Mice ; Mice, Inbred ICR ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose.
Autorzy :
Futatsugi K; Pfizer Inc. Medicine Design, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Smith AC; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Tu M; Pfizer Inc. Medicine Design, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Raymer B; Pfizer Inc. Medicine Design, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Ahn K; Pfizer Inc. Internal Medicine Research Unit, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Coffey SB; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Dowling MS; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Fernando DP; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Gutierrez JA; Pfizer Inc. Internal Medicine Research Unit, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Huard K; Pfizer Inc. Medicine Design, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Jasti J; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Kalgutkar AS; Pfizer Inc. Medicine Design, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Knafels JD; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Pandit J; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Parris KD; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Perez S; Pfizer Inc. Internal Medicine Research Unit, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Pfefferkorn JA; Pfizer Inc. Internal Medicine Research Unit, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Price DA; Pfizer Inc. Medicine Design, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Ryder T; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Shavnya A; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Stock IA; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Tsai AS; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Tesz GJ; Pfizer Inc. Internal Medicine Research Unit, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Thuma BA; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Weng Y; Pfizer Inc. Medicine Design, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Wisniewska HM; Pfizer Inc. Medicine Design, Eastern Point Road, Groton, Connecticut 06340, United States.
Xing G; Pfizer Inc. Internal Medicine Research Unit, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
Zhou J; Pfizer Inc. Drug Safety R&D, Eastern Point Road, Groton, Connecticut 06340, United States.
Magee TV; Pfizer Inc. Medicine Design, 1 Portland Street, Cambridge, Massachusetts 02139, United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Nov 25; Vol. 63 (22), pp. 13546-13560. Date of Electronic Publication: 2020 Sep 27.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Discovery/*methods
Enzyme Inhibitors/*chemistry
Fructokinases/*antagonists & inhibitors
Fructokinases/*metabolism
Fructose/*adverse effects
Metabolic Diseases/*enzymology
Animals ; Crystallography, X-Ray ; Dogs ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Fructose/administration & dosage ; Hepatocytes/drug effects ; Hepatocytes/enzymology ; Humans ; Insulin Resistance/physiology ; Male ; Metabolic Diseases/chemically induced ; Metabolic Diseases/drug therapy ; Protein Structure, Secondary ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Topoisomerase activity is linked to altered nucleosome positioning and transcriptional regulation in the fission yeast fbp1 gene.
Autorzy :
Asada R; Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji-shi, Tokyo, Japan.; Department of Viticulture and Enology, University of California, Davis, Davis, California, United States of America.
Senmatsu S; Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji-shi, Tokyo, Japan.
Montpetit B; Department of Viticulture and Enology, University of California, Davis, Davis, California, United States of America.
Hirota K; Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji-shi, Tokyo, Japan.
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Źródło :
PloS one [PLoS One] 2020 Nov 12; Vol. 15 (11), pp. e0242348. Date of Electronic Publication: 2020 Nov 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Topoisomerases/*metabolism
Fructose-Bisphosphatase/*metabolism
Nucleosomes/*genetics
Chromatin/metabolism ; Chromatin Assembly and Disassembly ; DNA/genetics ; DNA/metabolism ; DNA Topoisomerases/physiology ; Fructose-Bisphosphatase/genetics ; Gene Expression Regulation, Fungal/genetics ; Nucleosomes/metabolism ; Promoter Regions, Genetic/genetics ; Schizosaccharomyces/metabolism ; Schizosaccharomyces pombe Proteins/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic/genetics
Czasopismo naukowe
Tytuł :
Methane breath tests and blood sugar tests in children with suspected carbohydrate malabsorption.
Autorzy :
Schneider C; Department of Pediatrics, Rostock University Medical Center, Ernst-Heydemann-Str. 8, 18057, Rostock, Germany.
Wutzke KD; Department of Pediatrics, Rostock University Medical Center, Ernst-Heydemann-Str. 8, 18057, Rostock, Germany.
Däbritz J; Department of Pediatrics, Rostock University Medical Center, Ernst-Heydemann-Str. 8, 18057, Rostock, Germany. .; Centre for Immunobiology, Blizard Institute, Barts Cancer Institute, The Barts & The London School of Medicine & Dentistry, Queen Mary University of London, London, UK. .
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 04; Vol. 10 (1), pp. 18972. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fructose Intolerance/*diagnosis
Hydrogen/*analysis
Lactose Intolerance/*diagnosis
Methane/*analysis
Adolescent ; Blood Glucose ; Breath Tests ; Child ; Child, Preschool ; Female ; Fructose Intolerance/blood ; Humans ; Lactose Intolerance/blood ; Male ; Reproducibility of Results ; Retrospective Studies
Czasopismo naukowe

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