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    Wyświetlanie 1-13 z 13
    Tytuł:
    Author Correction: Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice.
    Autorzy:
    Stojakovic A; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Trushin S; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Sheu A; Institute for Translational Neuroscience, University of Minnesota Twin Cities, 2101 6th Street SE, Minneapolis, MN, 55455, USA.
    Khalili L; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Chang SY; Department of Neurologic Surgery, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Li X; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Christensen T; Microscopy and Cell Analysis Core, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Salisbury JL; Microscopy and Cell Analysis Core, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.; Department of Biochemistry and Molecular Biology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Geroux RE; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Gateno B; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Flannery PJ; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Dehankar M; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Funk CC; Institute for Systems Biology, Seattle, WA, 98109-5263, USA.
    Wilkins J; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Stepanova A; Division of Neonatology, Department of Pediatrics, Columbia University, 116th St & Broadway, New York, NY, 10027, USA.
    O'Hagan T; Division of Neonatology, Department of Pediatrics, Columbia University, 116th St & Broadway, New York, NY, 10027, USA.
    Galkin A; Division of Neonatology, Department of Pediatrics, Columbia University, 116th St & Broadway, New York, NY, 10027, USA.
    Nesbitt J; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Zhu X; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Tripathi U; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Macura S; Department of Biochemistry and Molecular Biology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Tchkonia T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Pirtskhalava T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Kirkland JL; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Kudgus RA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Schoon RA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Reid JM; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Yamazaki Y; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
    Kanekiyo T; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
    Zhang S; Department of Cardiovascular Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Nemutlu E; Faculty of Pharmacy, Department of Analytical Chemistry, Hacettepe University, Sihhiye, Ankara, 06100, Turkey.
    Dzeja P; Department of Cardiovascular Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Jaspersen A; Microscopy and Cell Analysis Core, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Kwon YIC; Institute for Translational Neuroscience, University of Minnesota Twin Cities, 2101 6th Street SE, Minneapolis, MN, 55455, USA.
    Lee MK; Institute for Translational Neuroscience, University of Minnesota Twin Cities, 2101 6th Street SE, Minneapolis, MN, 55455, USA.
    Trushina E; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. .; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. .
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    Źródło:
    Communications biology [Commun Biol] 2024 Feb 26; Vol. 7 (1), pp. 234. Date of Electronic Publication: 2024 Feb 26.
    Typ publikacji:
    Published Erratum
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
    Autorzy:
    Baloni P; Institute for Systems Biology, Seattle, WA, USA.; School of Health Sciences, Purdue University, West Lafayette, IN, USA.
    Arnold M; Institute of Computational Biology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, Durham, NC, USA.
    Buitrago L; Department of Neurology/Pharmacology, SUNY Downstate Medical Center, Brooklyn, NY, USA.
    Nho K; Indiana Alzheimer's Disease Research Center and Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.
    Moreno H; Department of Neurology/Pharmacology, SUNY Downstate Medical Center, Brooklyn, NY, USA.
    Huynh K; Metabolomics Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
    Brauner B; Institute of Computational Biology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
    Louie G; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, Durham, NC, USA.
    Kueider-Paisley A; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, Durham, NC, USA.
    Suhre K; Department of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, PO 24144, Doha, Qatar.
    Saykin AJ; Indiana Alzheimer's Disease Research Center and Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.
    Ekroos K; Lipidomics Consulting Ltd., Esbo, Finland.
    Meikle PJ; Metabolomics Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
    Hood L; Institute for Systems Biology, Seattle, WA, USA.
    Price ND; Institute for Systems Biology, Seattle, WA, USA.
    Doraiswamy PM; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, Durham, NC, USA.
    Funk CC; Institute for Systems Biology, Seattle, WA, USA.
    Hernández AI; Department of Pathology, SUNY Downstate Medical Center, Brooklyn, NY, USA.
    Kastenmüller G; Institute of Computational Biology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
    Baillie R; Rosa & Co LLC, San Carlos, CA, USA.
    Han X; University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. .
    Kaddurah-Daouk R; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, Durham, NC, USA. .; Department of Medicine, Duke University, Durham, NC, USA. .; Duke Institute of Brain Sciences, Duke University, Durham, NC, USA. .
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    Corporate Authors:
    Alzheimer’s Disease Metabolomics Consortium
    Źródło:
    Communications biology [Commun Biol] 2022 Oct 08; Vol. 5 (1), pp. 1074. Date of Electronic Publication: 2022 Oct 08.
    Typ publikacji:
    Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*/drug therapy
    Alzheimer Disease*/genetics
    Alzheimer Disease*/metabolism
    Animals ; Ceramides ; Fingolimod Hydrochloride ; Genome-Wide Association Study ; Humans ; Mice ; Sphingolipids/metabolism ; Sphingolipids/therapeutic use ; Sphingomyelins/therapeutic use
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Risk factors for severe COVID-19 differ by age for hospitalized adults.
    Autorzy:
    Molani S; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA.
    Hernandez PV; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA.; Washington University School of Medicine, St. Louis, MO, 63110, USA.
    Roper RT; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA.
    Duvvuri VR; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA.
    Baumgartner AM; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA.
    Goldman JD; Swedish Center for Research and Innovation, Seattle, WA, 98109, USA.; Providence St. Joseph Health, Renton, WA, 98057, USA.; Division of Allergy & Infectious Diseases, University of Washington, Seattle, WA, 98109, USA.
    Ertekin-Taner N; Department of Neuroscience, Department of Neurology, Mayo Clinic Jacksonville, Jacksonville, FL, 32224, USA.
    Funk CC; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA.
    Price ND; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA.; Onegevity, a Division of Thorne HealthTech, New York, NY, USA.
    Rappaport N; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA.
    Hadlock JJ; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA. .
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    Źródło:
    Scientific reports [Sci Rep] 2022 Apr 28; Vol. 12 (1), pp. 6568. Date of Electronic Publication: 2022 Apr 28.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    COVID-19*/epidemiology
    Adult ; Hospitalization ; Humans ; Middle Aged ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; United States
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
    Autorzy:
    Heath L; Institute for Systems Biology, Seattle, WA, USA. .; Sage Bionetworks, Seattle, WA, USA. .
    Earls JC; Institute for Systems Biology, Seattle, WA, USA.; Thorne HealthTech, New York, NY, USA.
    Magis AT; Institute for Systems Biology, Seattle, WA, USA.
    Kornilov SA; Institute for Systems Biology, Seattle, WA, USA.
    Lovejoy JC; Institute for Systems Biology, Seattle, WA, USA.
    Funk CC; Institute for Systems Biology, Seattle, WA, USA.
    Rappaport N; Institute for Systems Biology, Seattle, WA, USA.
    Logsdon BA; Sage Bionetworks, Seattle, WA, USA.
    Mangravite LM; Sage Bionetworks, Seattle, WA, USA.
    Kunkle BW; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
    Martin ER; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
    Naj AC; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
    Ertekin-Taner N; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
    Golde TE; Department of Neuroscience, College of Medicine, McKnight Brain Institute, Center for Translational Research in Neurodegenerative Disease University of Florida, Gainesville, FL, USA.
    Hood L; Institute for Systems Biology, Seattle, WA, USA.; Providence St. Joseph Health, Renton, WA, USA.
    Price ND; Institute for Systems Biology, Seattle, WA, USA. .; Thorne HealthTech, New York, NY, USA. .
    Pokaż więcej
    Corporate Authors:
    Alzheimer’s Disease Genetics Consortium
    Źródło:
    Scientific reports [Sci Rep] 2022 Apr 12; Vol. 12 (1), pp. 6117. Date of Electronic Publication: 2022 Apr 12.
    Typ publikacji:
    Journal Article; Meta-Analysis; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*/genetics
    ATP-Binding Cassette Transporters/genetics ; Adult ; Apolipoprotein E2/genetics ; Female ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Genomics ; Humans ; Male ; Polymorphism, Single Nucleotide
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice.
    Autorzy:
    Stojakovic A; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Trushin S; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Sheu A; Institute for Translational Neuroscience, University of Minnesota Twin Cities, 2101 6th Street SE, Minneapolis, MN, 55455, USA.
    Khalili L; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Chang SY; Department of Neurologic Surgery, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Li X; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Christensen T; Microscopy and Cell Analysis Core, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Salisbury JL; Microscopy and Cell Analysis Core, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.; Department of Biochemistry and Molecular Biology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Geroux RE; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Gateno B; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Flannery PJ; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Dehankar M; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Funk CC; Institute for Systems Biology, Seattle, WA, 98109-5263, USA.
    Wilkins J; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Stepanova A; Division of Neonatology, Department of Pediatrics, Columbia University, 116th St & Broadway, New York, NY, 10027, USA.
    O'Hagan T; Division of Neonatology, Department of Pediatrics, Columbia University, 116th St & Broadway, New York, NY, 10027, USA.
    Galkin A; Division of Neonatology, Department of Pediatrics, Columbia University, 116th St & Broadway, New York, NY, 10027, USA.
    Nesbitt J; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Zhu X; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Tripathi U; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Macura S; Department of Biochemistry and Molecular Biology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Tchkonia T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Pirtskhalava T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Kirkland JL; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Kudgus RA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Schoon RA; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Reid JM; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Yamazaki Y; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
    Kanekiyo T; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
    Zhang S; Department of Cardiovascular Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Nemutlu E; Faculty of Pharmacy, Department of Analytical Chemistry, Hacettepe University, Sihhiye, Ankara, 06100, Turkey.
    Dzeja P; Department of Cardiovascular Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Jaspersen A; Microscopy and Cell Analysis Core, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
    Kwon YIC; Institute for Translational Neuroscience, University of Minnesota Twin Cities, 2101 6th Street SE, Minneapolis, MN, 55455, USA.
    Lee MK; Institute for Translational Neuroscience, University of Minnesota Twin Cities, 2101 6th Street SE, Minneapolis, MN, 55455, USA.
    Trushina E; Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. .; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. .
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    Źródło:
    Communications biology [Commun Biol] 2021 Jan 08; Vol. 4 (1), pp. 61. Date of Electronic Publication: 2021 Jan 08.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease/*drug therapy
    Brain/*drug effects
    Cognition/*drug effects
    Electron Transport Complex I/*antagonists & inhibitors
    Pyrones/*therapeutic use
    Alzheimer Disease/metabolism ; Animals ; Brain/metabolism ; Brain/ultrastructure ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Female ; Mice, Inbred C57BL ; Mice, Transgenic ; Neuroprotection ; Proof of Concept Study ; Pyrones/pharmacology ; Signal Transduction/drug effects ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    iREAD: a tool for intron retention detection from RNA-seq data.
    Autorzy:
    Li HD; Center for Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha, Hunan Province, 410083, People's Republic of China.; Institute for Systems Biology, Seattle, WA, 98109, USA.
    Funk CC; Institute for Systems Biology, Seattle, WA, 98109, USA.
    Price ND; Institute for Systems Biology, Seattle, WA, 98109, USA. .
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    Źródło:
    BMC genomics [BMC Genomics] 2020 Feb 06; Vol. 21 (1), pp. 128. Date of Electronic Publication: 2020 Feb 06.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Introns*
    RNA-Seq*
    Software*
    Algorithms ; Animals ; Humans ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.Htt model of Huntington's disease.
    Autorzy:
    Bragg RM
    Coffey SR
    Weston RM
    Ament SA
    Cantle JP
    Minnig S
    Funk CC
    Shuttleworth DD
    Woods EL
    Sullivan BR
    Jones L
    Glickenhaus A
    Anderson JS
    Anderson MD
    Dunnett SB
    Wheeler VC
    MacDonald ME
    Brooks SP
    Price ND
    Carroll JB
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    Źródło:
    Scientific reports [Sci Rep] 2017 Mar 28; Vol. 7, pp. 44960. Date of Electronic Publication: 2017 Mar 28.
    Typ publikacji:
    Journal Article; Published Erratum
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Ion channel expression patterns in glioblastoma stem cells with functional and therapeutic implications for malignancy.
    Autorzy:
    Pollak J; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, United States of America.
    Rai KG; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, United States of America.
    Funk CC; Institute for Systems Biology, Seattle, Washington, United States of America.
    Arora S; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
    Lee E; Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
    Zhu J; Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Department of Hematology and Medical Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
    Price ND; Institute for Systems Biology, Seattle, Washington, United States of America.
    Paddison PJ; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
    Ramirez JM; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, United States of America.; Department of Neurosurgery, University of Washington, Seattle, Washington, United States of America.
    Rostomily RC; Department of Neurosurgery, University of Washington, Seattle, Washington, United States of America.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington, United States of America.; Houston Methodist Research Institute, Houston, Texas, United States of America.; Department of Neurosurgery, Houston Methodist Hospital, Houston, Texas, United States of America.
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    Źródło:
    PloS one [PLoS One] 2017 Mar 06; Vol. 12 (3), pp. e0172884. Date of Electronic Publication: 2017 Mar 06 (Print Publication: 2017).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Expression Regulation, Neoplastic*
    Brain Neoplasms/*genetics
    Glioblastoma/*genetics
    Ion Channels/*genetics
    Neoplastic Stem Cells/*metabolism
    Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Brain Neoplasms/therapy ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Cluster Analysis ; Gap Junctions/genetics ; Gap Junctions/metabolism ; Gene Expression Profiling ; Gene Knockdown Techniques ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Glioblastoma/therapy ; Humans ; Ion Channels/metabolism ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/pathology ; Prognosis ; Signal Transduction ; Survival Analysis ; Transcriptome ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.Htt model of Huntington's disease.
    Autorzy:
    Bragg RM; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Coffey SR; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Weston RM; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA.
    Ament SA; Institute for Systems Biology, Seattle, WA, USA.; Institute for Genome Sciences and Department of Psychiatry, University of Maryland School of Medicine, Baltimore, USA.
    Cantle JP; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Minnig S; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Funk CC; Institute for Systems Biology, Seattle, WA, USA.
    Shuttleworth DD; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Woods EL; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Sullivan BR; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Jones L; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Glickenhaus A; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Anderson JS; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Anderson MD; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.
    Dunnett SB; The Brain Repair Group, Cardiff University School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff, Wales CF10 3AX, United Kingdom.
    Wheeler VC; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston 02114, MA, USA.
    MacDonald ME; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston 02114, MA, USA.
    Brooks SP; The Brain Repair Group, Cardiff University School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff, Wales CF10 3AX, United Kingdom.
    Price ND; Institute for Systems Biology, Seattle, WA, USA.
    Carroll JB; Behavioral Neuroscience Program, Department of Psychology, Western Washington University, Bellingham, WA, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston 02114, MA, USA.
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    Źródło:
    Scientific reports [Sci Rep] 2017 Feb 08; Vol. 7, pp. 41570. Date of Electronic Publication: 2017 Feb 08.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Transcriptional analysis of aggressiveness and heterogeneity across grades of astrocytomas.
    Autorzy:
    Wang C; Institute for Systems Biology, Seattle, Washington, United States of America ; Department of Chemical and Biomolecular Engineering, University of Illinois, Urbana, Illinois, United States of America.
    Funk CC
    Eddy JA
    Price ND
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    Źródło:
    PloS one [PLoS One] 2013 Oct 11; Vol. 8 (10), pp. e76694. Date of Electronic Publication: 2013 Oct 11 (Print Publication: 2013).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Expression Profiling*
    Genetic Heterogeneity*
    Astrocytoma/*genetics
    Astrocytoma/*pathology
    Brain Neoplasms/*genetics
    Brain Neoplasms/*pathology
    Algorithms ; Carcinogenesis/genetics ; Carcinogenesis/pathology ; Databases, Genetic ; Disease Progression ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Genes, Neoplasm ; Humans ; Neoplasm Grading ; Neoplasm Invasiveness ; Oligonucleotide Array Sequence Analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    AUREA: an open-source software system for accurate and user-friendly identification of relative expression molecular signatures.
    Autorzy:
    Earls JC; Institute for Systems Biology, Seattle, WA, USA.
    Eddy JA
    Funk CC
    Ko Y
    Magis AT
    Price ND
    Pokaż więcej
    Źródło:
    BMC bioinformatics [BMC Bioinformatics] 2013 Mar 05; Vol. 14, pp. 78. Date of Electronic Publication: 2013 Mar 05.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Software*
    Transcriptome*
    Algorithms ; Databases, Genetic ; User-Computer Interface
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Multi-study integration of brain cancer transcriptomes reveals organ-level molecular signatures.
    Autorzy:
    Sung J; Institute for Systems Biology, Seattle, Washington, United States of America.
    Kim PJ
    Ma S
    Funk CC
    Magis AT
    Wang Y
    Hood L
    Geman D
    Price ND
    Pokaż więcej
    Źródło:
    PLoS computational biology [PLoS Comput Biol] 2013; Vol. 9 (7), pp. e1003148. Date of Electronic Publication: 2013 Jul 25.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Transcriptome*
    Brain Neoplasms/*genetics
    Biomarkers, Tumor/metabolism ; Brain Neoplasms/metabolism ; Computational Biology ; Humans ; Reproducibility of Results
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Climate. Food security under climate change.
    Autorzy:
    Brown ME; Science Systems and Applications, Inc., NASA Goddard Space Flight Center Biospheric Sciences Branch, Code 614.4, Greenbelt, MD 20771, USA. />Funk CC
    Pokaż więcej
    Źródło:
    Science (New York, N.Y.) [Science] 2008 Feb 01; Vol. 319 (5863), pp. 580-1.
    Typ publikacji:
    Comment; Journal Article
    MeSH Terms:
    Agriculture*/economics
    Agriculture*/methods
    Agriculture*/trends
    Climate*
    Crops, Agricultural*/economics
    Food Supply*/economics
    Costs and Cost Analysis ; Developing Countries ; Forecasting ; Humans ; Malnutrition/etiology ; Models, Statistical ; Poverty ; Tropical Climate
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-13 z 13

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