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Wyszukujesz frazę ""Furans"" wg kryterium: Temat


Tytuł :
Protocatechuic acid protects against hepatorenal toxicities in rats exposed to Furan.
Autorzy :
Owumi SE; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, University of Ibadan, Ibadan, Nigeria.
Bello SA; Nutrition and Industrial Biochemistry Laboratories, Department of Biochemistry, University of Ibadan, Ibadan, Nigeria.
Idowu TB; Nutrition and Industrial Biochemistry Laboratories, Department of Biochemistry, University of Ibadan, Ibadan, Nigeria.
Arunsi UO; Department of Cancer Immunology and Biotechnology, School of Medicine, University of Nottingham, Nottingham, UK.
Oyelere AK; School of Biochemistry and Chemistry, Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, USA.
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Źródło :
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Jul; Vol. 45 (4), pp. 1840-1850. Date of Electronic Publication: 2021 Feb 28.
Typ publikacji :
Journal Article
MeSH Terms :
Furans*/toxicity
Hydroxybenzoates*/pharmacology
Kidney*/drug effects
Kidney*/pathology
Liver*/drug effects
Liver*/pathology
Tumor Necrosis Factor-alpha*/metabolism
Animals ; Antioxidants/metabolism ; Interleukin-10/metabolism ; Oxidative Stress ; Rats ; Reactive Nitrogen Species/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Replacing liquid chromatography with tailored ion chromatography: A green method for detecting furfuryl alcohol and understanding its properties.
Autorzy :
Yang Y; State Key Laboratory of Urban Water Resource and Environment, Shenzhen Key Laboratory of Organic Pollution Prevention and Control, Harbin Institute of Technology, Shenzhen 518055, China.
Wei Y; State Key Laboratory of Urban Water Resource and Environment, Shenzhen Key Laboratory of Organic Pollution Prevention and Control, Harbin Institute of Technology, Shenzhen 518055, China.
Li J; State Key Laboratory of Urban Water Resource and Environment, Shenzhen Key Laboratory of Organic Pollution Prevention and Control, Harbin Institute of Technology, Shenzhen 518055, China.
Chen B; State Key Laboratory of Urban Water Resource and Environment, Shenzhen Key Laboratory of Organic Pollution Prevention and Control, Harbin Institute of Technology, Shenzhen 518055, China. Electronic address: .
Ma W; State Key Laboratory of Urban Water Resource and Environment, Shenzhen Key Laboratory of Organic Pollution Prevention and Control, Harbin Institute of Technology, Shenzhen 518055, China.
Liu W; State Key Laboratory of Urban Water Resource and Environment, Shenzhen Key Laboratory of Organic Pollution Prevention and Control, Harbin Institute of Technology, Shenzhen 518055, China.
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2022 Jun 21; Vol. 1673, pp. 463090. Date of Electronic Publication: 2022 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Furans*/chemistry
Hydrogen Peroxide*/chemistry
Chromatography, Liquid ; Humans ; Solvents ; Water
Czasopismo naukowe
Tytuł :
Rotational Spectroscopy of 2-Furoic Acid and Its Dimer: Conformational Distribution and Double Proton Tunneling.
Autorzy :
Insausti A; Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.; Departamento de Química Física, Universidad del País Vasco (UPV/EHU), Barrio Sarriena s/n, 48940, Leioa, Spain.; Instituto Biofisika (UPV/EHU, CSIC), Barrio Sarriena s/n, 48940, Leioa, Spain.
Ma J; Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.
Yang Q; Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.
Xie F; Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.; Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
Xu Y; Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.
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Źródło :
Chemphyschem : a European journal of chemical physics and physical chemistry [Chemphyschem] 2022 Jun 20; Vol. 23 (12), pp. e202200176. Date of Electronic Publication: 2022 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
Furans*
Protons*
Molecular Conformation ; Spectrum Analysis
Czasopismo naukowe
Tytuł :
Convergent Synthesis of the C1-C29 Framework of Amphidinolide F.
Autorzy :
Romiti F; School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, U.K.
Decultot L; School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, U.K.
Clark JS; School of Chemistry, University of Glasgow, Joseph Black Building, University Avenue, Glasgow G12 8QQ, U.K.
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Źródło :
The Journal of organic chemistry [J Org Chem] 2022 Jun 17; Vol. 87 (12), pp. 8126-8141. Date of Electronic Publication: 2022 Jun 08.
Typ publikacji :
Journal Article
MeSH Terms :
Furans*
Macrolides*
Molecular Structure ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Phase 1 study of the liposomal formulation of eribulin (E7389-LF): Results from the breast cancer expansion cohort.
Autorzy :
Masuda N; Department of Surgery, Breast Oncology, National Hospital Organization Osaka National Hospital, Osaka, Japan. Electronic address: .
Ono M; Department of Medical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Mukohara T; Department of Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Yasojima H; Department of Surgery, Breast Oncology, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Shimoi T; Department of Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
Kobayashi K; Department of Breast Medical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Harano K; Department of Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Mizutani M; Department of Surgery, Breast Oncology, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Tanioka M; Department of Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
Takahashi S; Department of Medical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Kogawa T; Department of Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Suzuki T; Japan and Asia Clinical Development Department, Oncology Business Group, Eisai Co., Ltd., Tokyo, Japan.
Okumura S; Japan and Asia Clinical Development Department, Oncology Business Group, Eisai Co., Ltd., Tokyo, Japan.
Takase T; Clinical Data Science Department, Medicine Development Center, Eisai Co., Ltd., Tokyo, Japan.
Nagai R; Clinical Data Science Department, Medicine Development Center, Eisai Co., Ltd., Tokyo, Japan.
Semba T; Tsukuba Research Department, Oncology Business Group, Eisai Co., Ltd., Ibaraki, Japan.
Zhao ZM; Translational Science, Oncology Business Group, Eisai Inc., Nutley, NJ, USA.
Ren M; Biostats, Oncology Business Group, Eisai Inc., Nutley, NJ, USA.
Yonemori K; Department of Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
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Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2022 Jun; Vol. 168, pp. 108-118. Date of Electronic Publication: 2022 Apr 29.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms*/drug therapy
Breast Neoplasms*/pathology
Furans*/adverse effects
Ketones*/adverse effects
Cohort Studies ; Drug Compounding ; Febrile Neutropenia ; Female ; Humans ; Liposomes ; Triple Negative Breast Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
Identification of 2-furanmethanethiol contributing to roast aroma in honkaku shochu and awamori.
Autorzy :
Osafune Y; National Research Institute of Brewing, 3-7-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-0046, Japan. Electronic address: .
Toshida K; National Research Institute of Brewing, 3-7-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-0046, Japan.
Han J; National Research Institute of Brewing, 3-7-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-0046, Japan.
Kishimoto T; National Research Institute of Brewing, 3-7-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-0046, Japan.
Iizuka-Furukawa S; National Research Institute of Brewing, 3-7-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-0046, Japan.
Isogai A; National Research Institute of Brewing, 3-7-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-0046, Japan.
Mukai N; National Research Institute of Brewing, 3-7-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-0046, Japan.
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Źródło :
Journal of bioscience and bioengineering [J Biosci Bioeng] 2022 Jun; Vol. 133 (6), pp. 555-559. Date of Electronic Publication: 2022 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
Furans*
Odorants*/analysis
Fermentation ; Sulfhydryl Compounds
Czasopismo naukowe
Tytuł :
Theoretical Studies of Furan and Thiophene Nanothreads: Structures, Cycloaddition Barriers, and Activation Volumes.
Autorzy :
Chen B; Donostia International Physics Center, Paseo Manuel de Lardizabal, 4, Donostia-San Sebastian 20018, Spain.; Ikerbasque, Basque Foundation for Science, Plaza Euskadi 5, Bilbao 48009, Spain.
Crespi VH; Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Department of Physics, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Materials Research Institute, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.; Department of Materials Science and Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Hoffmann R; Baker Laboratory, Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
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Źródło :
Journal of the American Chemical Society [J Am Chem Soc] 2022 May 25; Vol. 144 (20), pp. 9044-9056. Date of Electronic Publication: 2022 May 12.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Furans*/chemistry
Thiophenes*
Cycloaddition Reaction ; Models, Theoretical ; Polymers/chemistry
Czasopismo naukowe
Tytuł :
Molecular Dynamics Study of the Photodegradation of Polymeric Chains.
Autorzy :
Erickson M; Department of Coatings and Polymeric Materials, North Dakota State University, Fargo, North Dakota 58108, United States.
Han Y; Department of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States.
Rasulev B; Department of Coatings and Polymeric Materials, North Dakota State University, Fargo, North Dakota 58108, United States.
Kilin D; Department of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States.
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Źródło :
The journal of physical chemistry letters [J Phys Chem Lett] 2022 May 19; Vol. 13 (19), pp. 4374-4380. Date of Electronic Publication: 2022 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Dicarboxylic Acids*/chemistry
Dicarboxylic Acids*/metabolism
Furans*/chemistry
Biomass ; Molecular Dynamics Simulation ; Photolysis ; Water
Czasopismo naukowe
Tytuł :
Conditions to Control Furan Ring Opening during Furfuryl Alcohol Polymerization.
Autorzy :
Quinquet L; Institut de Chimie de Nice, Université Côte d'Azur, CNRS, UMR 7272, 06108 Nice, France.
Delliere P; Institut de Chimie de Nice, Université Côte d'Azur, CNRS, UMR 7272, 06108 Nice, France.
Guigo N; Institut de Chimie de Nice, Université Côte d'Azur, CNRS, UMR 7272, 06108 Nice, France.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2022 May 17; Vol. 27 (10). Date of Electronic Publication: 2022 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Esters*
Furans*/chemistry
Polymerization ; Spectroscopy, Fourier Transform Infrared ; Water
Czasopismo naukowe
Tytuł :
An Easy Access to Furan-Fused Polyheterocyclic Systems.
Autorzy :
Benzi A; Dipartimento di Chimica e Chimica Industriale, Università degli Studi di Genova, Via Dodecaneso 31, 16146 Genova, Italy.
Bianchi L; Dipartimento di Chimica e Chimica Industriale, Università degli Studi di Genova, Via Dodecaneso 31, 16146 Genova, Italy.
Giorgi G; Dipartimento di Biotecnologie, Chimica e Farmacia, Università di Siena, Via A. Moro, 53100 Siena, Italy.
Maccagno M; Dipartimento di Chimica e Chimica Industriale, Università degli Studi di Genova, Via Dodecaneso 31, 16146 Genova, Italy.
Petrillo G; Dipartimento di Chimica e Chimica Industriale, Università degli Studi di Genova, Via Dodecaneso 31, 16146 Genova, Italy.
Spinelli D; Dipartimento di Chimica 'G. Ciamician', Alma Mater Studiorum-University of Bologna, Via F. Selmi 2, 40126 Bologna, Italy.
Tavani C; Dipartimento di Chimica e Chimica Industriale, Università degli Studi di Genova, Via Dodecaneso 31, 16146 Genova, Italy.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2022 May 14; Vol. 27 (10). Date of Electronic Publication: 2022 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Carbon*/chemistry
Furans*/chemistry
Alcohols ; Amines ; Thiophenes
Czasopismo naukowe
Tytuł :
Effects of 3, 4-divanillyltetrahydrofuran from Urtica fissa on sexual dysfunction in diabetic mice.
Autorzy :
Yang WJ; School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, China. Electronic address: .
Ma YM; College of Chemistry and Chemical Engineering(,), Shaanxi University of Science & Technology, Xi'an, 710021, China; Key Laboratory of Chemical Additives for China National Light Industry, Xi'an, 710021, China. Electronic address: .
Gong P; School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, China. Electronic address: .
Wang L; School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, China. Electronic address: .
Chang XN; School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, China. Electronic address: .
Liu M; School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, China. Electronic address: .
Shuai ZR; School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an, 710021, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 May 10; Vol. 289, pp. 115060. Date of Electronic Publication: 2022 Feb 01.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental/*drug therapy
Furans/*pharmacology
Hypogonadism/*drug therapy
Lignin/*pharmacology
Urticaceae/*chemistry
Animals ; Diabetes Mellitus, Experimental/complications ; Female ; Furans/isolation & purification ; Gene Expression Regulation/drug effects ; Hypogonadism/etiology ; Insulin Resistance ; Lignin/isolation & purification ; Male ; Mice ; Mice, Inbred ICR ; Molecular Docking Simulation ; Nuclear Receptor Subfamily 4, Group A, Member 1/genetics ; Sexual Behavior, Animal/drug effects ; Sexual Dysfunction, Physiological/drug therapy ; Sexual Dysfunction, Physiological/etiology ; Streptozocin ; Testis/drug effects ; Testosterone/blood
Czasopismo naukowe
Tytuł :
Enzymatic Cascade for the Synthesis of 2,5-Furandicarboxylic Acid in Biphasic and Microaqueous Conditions: 'Media-Agnostic' Biocatalysts for Biorefineries.
Autorzy :
Milić M; Biocatalysis and Bioprocessing Group, Department of Biological and Chemical Engineering, Aarhus University, Gustav Wieds Vej 10, 8000, Aarhus C, Denmark.
Byström E; SpinChem AB, Tvistevägen 48C, SE-90736, Umeå, Sweden.
Domínguez de María P; Sustainable Momentum S L, Av. Ansite 3, 4-6, 35011, Las Palmas de Gran Canaria, Spain.
Kara S; Biocatalysis and Bioprocessing Group, Department of Biological and Chemical Engineering, Aarhus University, Gustav Wieds Vej 10, 8000, Aarhus C, Denmark.; Institute of Technical Chemistry, Leibniz University Hannover, Callinstr. 5, 30167, Hannover, Germany.
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Źródło :
ChemSusChem [ChemSusChem] 2022 May 06; Vol. 15 (9), pp. e202102704. Date of Electronic Publication: 2022 Apr 19.
Typ publikacji :
Journal Article
MeSH Terms :
Dicarboxylic Acids*
Furans*
Biocatalysis ; Galactose Oxidase ; Water
Czasopismo naukowe
Tytuł :
Synthesis, Reactivity, and Properties of Benz[ a ]azulenes via the [8 + 2] Cycloaddition of 2 H -Cyclohepta[ b ]furan-2-ones with an Enamine.
Autorzy :
Shoji T; Graduate School of Science and Technology, Shinshu University, Matsumoto 390-8621, Japan.; Department of Chemical Biology and Applied Chemistry, College of Engineering, Nihon University, Koriyama 963-8642, Japan.
Yamazaki A; Graduate School of Science and Technology, Shinshu University, Matsumoto 390-8621, Japan.
Katoh R; Department of Chemical Biology and Applied Chemistry, College of Engineering, Nihon University, Koriyama 963-8642, Japan.
Shimamura K; Department of Chemical Biology and Applied Chemistry, College of Engineering, Nihon University, Koriyama 963-8642, Japan.
Sakai R; Department of Chemical Biology and Applied Chemistry, College of Engineering, Nihon University, Koriyama 963-8642, Japan.
Yasunami M; Department of Chemical Biology and Applied Chemistry, College of Engineering, Nihon University, Koriyama 963-8642, Japan.
Okujima T; Department of Chemistry and Biology, Graduate School of Science and Engineering, Ehime University, Matsuyama 790-8577, Japan.
Ito S; Graduate School of Science and Technology, Hirosaki University, Hirosaki 036-8561, Japan.
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Źródło :
The Journal of organic chemistry [J Org Chem] 2022 May 06; Vol. 87 (9), pp. 5827-5845. Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Azulenes*/chemistry
Furans*
Cyclization ; Cycloaddition Reaction ; Magnetic Resonance Spectroscopy
Czasopismo naukowe
Tytuł :
A molecular substitutional disorder case study suitable for instruction: L 2 Cr (L is 2,5-bis{[(2,6-diisopropylphenyl)imino]methyl}pyrrol-1-ide).
Autorzy :
Salisbury BA; Department of Chemistry and Biochemistry, Center for Catalytic Science and Technology, University of Delaware, Newark, DE 18716, USA.
Young JF; Department of Chemistry and Biochemistry, Center for Catalytic Science and Technology, University of Delaware, Newark, DE 18716, USA.
Theopold KH; Department of Chemistry and Biochemistry, Center for Catalytic Science and Technology, University of Delaware, Newark, DE 18716, USA.
Yap GPA; Department of Chemistry and Biochemistry, Center for Catalytic Science and Technology, University of Delaware, Newark, DE 18716, USA.
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Źródło :
Acta crystallographica. Section C, Structural chemistry [Acta Crystallogr C Struct Chem] 2022 May 01; Vol. 78 (Pt 5), pp. 295-298. Date of Electronic Publication: 2022 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Chromium*/chemistry
Furans*/chemistry
Chromium Compounds/*chemistry
Crystallography, X-Ray ; Hydrogen Bonding ; Ligands
Czasopismo naukowe
Tytuł :
Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main protease.
Autorzy :
Dou X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Sun Q; BNLMS, Peking-Tsinghua Center for Life Sciences at College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Xu G; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Liu Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Zhang C; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Wang B; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Lu Y; BNLMS, Peking-Tsinghua Center for Life Sciences at College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Guo Z; BNLMS, Peking-Tsinghua Center for Life Sciences at College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Su L; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Huo T; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Zhao X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Wang C; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Yu Z; BNLMS, Peking-Tsinghua Center for Life Sciences at College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Song S; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Zhang L; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Liu Z; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Lai L; BNLMS, Peking-Tsinghua Center for Life Sciences at College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China; Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China. Electronic address: .
Jiao N; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2022 Aug 05; Vol. 238, pp. 114508. Date of Electronic Publication: 2022 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/drug therapy
Coronavirus 3C Proteases*/antagonists & inhibitors
Coronavirus 3C Proteases*/chemistry
Coronavirus 3C Proteases*/metabolism
Furans*/chemistry
Furans*/pharmacology
SARS-CoV-2*/drug effects
SARS-CoV-2*/enzymology
Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Drug Discovery/methods ; Humans ; Hydrazines/pharmacology ; Molecular Docking Simulation ; Protease Inhibitors/chemistry ; Protease Inhibitors/pharmacology
Czasopismo naukowe
Tytuł :
Development of Novel Dihydrofuro[3,4- d ]pyrimidine Derivatives as HIV-1 NNRTIs to Overcome the Highly Resistant Mutant Strains F227L/V106A and K103N/Y181C.
Autorzy :
Kang D; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Sun Y; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Feng D; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Gao S; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Wang Z; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Jing L; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Zhang T; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Jiang X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Lin H; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
De Clercq E; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000 Leuven, Belgium.
Pannecouque C; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000 Leuven, Belgium.
Zhan P; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Liu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2022 Feb 10; Vol. 65 (3), pp. 2458-2470. Date of Electronic Publication: 2022 Jan 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents/*pharmacology
Furans/*pharmacology
HIV Reverse Transcriptase/*antagonists & inhibitors
HIV-1/*drug effects
Pyrimidines/*pharmacology
Reverse Transcriptase Inhibitors/*pharmacology
Animals ; Anti-HIV Agents/chemical synthesis ; Anti-HIV Agents/metabolism ; Anti-HIV Agents/pharmacokinetics ; Drug Design ; Female ; Furans/chemical synthesis ; Furans/metabolism ; Furans/pharmacokinetics ; HIV Reverse Transcriptase/genetics ; HIV Reverse Transcriptase/metabolism ; HIV-1/enzymology ; Male ; Mice ; Molecular Docking Simulation ; Molecular Structure ; Mutation ; Protein Binding ; Pyrimidines/chemical synthesis ; Pyrimidines/metabolism ; Pyrimidines/pharmacokinetics ; Rats, Sprague-Dawley ; Reverse Transcriptase Inhibitors/chemical synthesis ; Reverse Transcriptase Inhibitors/metabolism ; Reverse Transcriptase Inhibitors/pharmacokinetics ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
The Tetrahydrofuran Motif in Polyketide Marine Drugs.
Autorzy :
Fernández-Peña L; Department of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, Spain.
Díez-Poza C; Department of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, Spain.
González-Andrés P; Department of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, Spain.
Barbero A; Department of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, Spain.
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Źródło :
Marine drugs [Mar Drugs] 2022 Feb 03; Vol. 20 (2). Date of Electronic Publication: 2022 Feb 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biological Products/*pharmacology
Furans/*pharmacology
Polyketides/*pharmacology
Animals ; Aquatic Organisms ; Biological Products/chemistry ; Biological Products/isolation & purification ; Furans/chemistry ; Furans/isolation & purification ; Humans ; Polyketides/chemistry ; Polyketides/isolation & purification
Czasopismo naukowe
Tytuł :
Optimization of G-CSF dosing schedule in patients treated with eribulin: a modeling approach.
Autorzy :
Reda M; Oncology Department, Centre Georges-François Leclerc, Dijon, France.
Macaire P; Pharmacy Department, Centre Georges-François Leclerc, 1 rue Pr Marion, 21079, Dijon, France.; INSERM U1231, University of Burgundy Franche-Comté, Dijon, France.
Bellio H; Oncology Department, Centre Georges-François Leclerc, Dijon, France.
Uwer L; Oncology Department, Institut de Cancérologie de Lorraine, Alexis Vautrin, Vandœuvre-lès-Nancy, France.
Ilie S; Oncology Department, Centre Georges-François Leclerc, Dijon, France.
Lorgis V; Oncology Department, Centre Georges-François Leclerc, Dijon, France.
Hennequin A; Oncology Department, Centre Georges-François Leclerc, Dijon, France.
Ladoire S; Oncology Department, Centre Georges-François Leclerc, Dijon, France.; Pharmacy Department, Centre Georges-François Leclerc, 1 rue Pr Marion, 21079, Dijon, France.
Rederstorff E; Department of Epidemiology and Biostatistics, Georges François Leclerc Center, Dijon, France.
Fumoleau P; Oncology Department, Centre Georges-François Leclerc, Dijon, France.
Isambert N; Oncology Department, Centre Georges-François Leclerc, Dijon, France.
Bonnin N; Medical Oncology, Institut de Cancérologie des Hospices Civils de Lyon (IC-HCL), CITOHL, Université Claude Bernard Lyon 1, GINECO, Lyon, France.
You B; Medical Oncology, Institut de Cancérologie des Hospices Civils de Lyon (IC-HCL), CITOHL, Université Claude Bernard Lyon 1, GINECO, Lyon, France.
Freyer G; Medical Oncology, Institut de Cancérologie des Hospices Civils de Lyon (IC-HCL), CITOHL, Université Claude Bernard Lyon 1, GINECO, Lyon, France.
Desmoulins I; Oncology Department, Centre Georges-François Leclerc, Dijon, France.
Schmitt A; Pharmacy Department, Centre Georges-François Leclerc, 1 rue Pr Marion, 21079, Dijon, France. .; INSERM U1231, University of Burgundy Franche-Comté, Dijon, France. .
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Źródło :
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2022 Feb; Vol. 89 (2), pp. 197-208. Date of Electronic Publication: 2022 Jan 08.
Typ publikacji :
Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Biological*
Antineoplastic Agents/*administration & dosage
Breast Neoplasms/*drug therapy
Furans/*administration & dosage
Granulocyte Colony-Stimulating Factor/*administration & dosage
Ketones/*administration & dosage
Adult ; Aged ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/pharmacokinetics ; Drug Administration Schedule ; Female ; Furans/adverse effects ; Furans/pharmacokinetics ; Humans ; Ketones/adverse effects ; Ketones/pharmacokinetics ; Middle Aged ; Neutropenia/chemically induced ; Neutropenia/prevention & control
Czasopismo naukowe
Tytuł :
Clinical and preclinical features of eribulin-related peripheral neuropathy.
Autorzy :
Tarasiuk O; School of Medicine and Surgery, Experimental Neurology Unit and Milan Center for Neuroscience, University of Milano-Bicocca, Monza, Italy.
Cavaletti G; School of Medicine and Surgery, Experimental Neurology Unit and Milan Center for Neuroscience, University of Milano-Bicocca, Monza, Italy. Electronic address: .
Meregalli C; School of Medicine and Surgery, Experimental Neurology Unit and Milan Center for Neuroscience, University of Milano-Bicocca, Monza, Italy.
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Źródło :
Experimental neurology [Exp Neurol] 2022 Feb; Vol. 348, pp. 113925. Date of Electronic Publication: 2021 Nov 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Furans/*therapeutic use
Ketones/*therapeutic use
Microtubules/*drug effects
Peripheral Nervous System Diseases/*chemically induced
Animals ; Antineoplastic Agents/metabolism ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Clinical Trials as Topic/methods ; Drug Evaluation, Preclinical/methods ; Furans/metabolism ; Furans/pharmacology ; Humans ; Ketones/metabolism ; Ketones/pharmacology ; Microtubules/metabolism ; Peripheral Nervous System Diseases/metabolism ; Peripheral Nervous System Diseases/prevention & control
Czasopismo naukowe
Tytuł :
Analysis of furan and its major furan derivatives in coffee products on the Chinese market using HS-GC-MS and the estimated exposure of the Chinese population.
Autorzy :
Cao P; China National Center for Food Safety Risk Assessment, Beijing 100022, China. Electronic address: .
Zhang L; China National Center for Food Safety Risk Assessment, Beijing 100022, China. Electronic address: .
Yang Y; Chinese Academy of Inspection and Quarantine, Beijing 100176, China. Electronic address: .
Wang XD; China National Center for Food Safety Risk Assessment, Beijing 100022, China. Electronic address: .
Liu ZP; China National Center for Food Safety Risk Assessment, Beijing 100022, China.
Li JW; China National Center for Food Safety Risk Assessment, Beijing 100022, China. Electronic address: .
Wang LY; Zhe Jiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China. Electronic address: .
Chung S; Faculty of Medicine, Macau University of Science and Technology, Macao, China. Electronic address: .
Zhou M; Center for Statistical Science & Department of Industrial Engineering, Tsinghua University, Beijing 100084, China.
Deng K; Center for Statistical Science & Department of Industrial Engineering, Tsinghua University, Beijing 100084, China. Electronic address: .
Zhou PP; China National Center for Food Safety Risk Assessment, Beijing 100022, China. Electronic address: .
Wu PG; Zhe Jiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2022 Sep 01; Vol. 387, pp. 132823. Date of Electronic Publication: 2022 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Coffee*/chemistry
Furans*/analysis
China ; Gas Chromatography-Mass Spectrometry/methods
Czasopismo naukowe

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