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Tytuł:
Gold Particle Analyser: Detection and quantitative assessment of electron microscopy gold probes.
Autorzy:
Burgoyne T; UCL Institute of Ophthalmology, London, United Kingdom.; Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Futter CE; UCL Institute of Ophthalmology, London, United Kingdom.
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Źródło:
PloS one [PLoS One] 2023 Jul 28; Vol. 18 (7), pp. e0288811. Date of Electronic Publication: 2023 Jul 28 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Silver*
Gold Colloid*/analysis
Immunohistochemistry ; Microscopy, Electron ; Antibodies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Changes in Mitochondrial Size and Morphology in the RPE and Photoreceptors of the Developing and Ageing Zebrafish.
Autorzy:
Burgoyne T; UCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.; Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London SW3 6NP, UK.
Toms M; UCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.; The Francis Crick Institute, London NW1 1AT, UK.
Way C; UCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.
Tracey-White D; UCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.
Futter CE; UCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.
Moosajee M; UCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.; The Francis Crick Institute, London NW1 1AT, UK.; Department of Ophthalmology, Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.; Department of Genetics, Moorfields Eye Hospital NHS Foundation Trust, London EC1V 2PD, UK.
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Źródło:
Cells [Cells] 2022 Nov 09; Vol. 11 (22). Date of Electronic Publication: 2022 Nov 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Retinal Pigment Epithelium*/metabolism
Zebrafish*
Animals ; Mitochondrial Size ; Retina/physiology ; Aging
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Current methods to analyze lysosome morphology, positioning, motility and function.
Autorzy:
Barral DC; CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal.
Staiano L; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.; Institute for Genetic and Biomedical Research, National Research Council (CNR), Milan, Italy.
Guimas Almeida C; CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal.
Cutler DF; MRC Laboratory for Molecular Cell Biology, University College London, London, UK.
Eden ER; University College London (UCL) Institute of Ophthalmology, London, UK.
Futter CE; University College London (UCL) Institute of Ophthalmology, London, UK.
Galione A; Department of Pharmacology, University of Oxford, Oxford, UK.
Marques ARA; CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal.
Medina DL; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.; Medical Genetics Unit, Department of Medical and Translational Science, Federico II University, Naples, Italy.
Napolitano G; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.; Medical Genetics Unit, Department of Medical and Translational Science, Federico II University, Naples, Italy.
Settembre C; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.; Clinical Medicine and Surgery Department, Federico II University, Naples, Italy.
Vieira OV; CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal.
Aerts JMFG; Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
Atakpa-Adaji P; Department of Pharmacology, University of Cambridge, Cambridge, UK.
Bruno G; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
Capuozzo A; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
De Leonibus E; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.; Institute of Biochemistry and Cell Biology, CNR, Rome, Italy.
Di Malta C; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.; Medical Genetics Unit, Department of Medical and Translational Science, Federico II University, Naples, Italy.
Escrevente C; CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal.
Esposito A; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
Grumati P; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
Hall MJ; CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal.
Teodoro RO; CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal.
Lopes SS; CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal.
Luzio JP; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Monfregola J; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
Montefusco S; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
Platt FM; Department of Pharmacology, University of Oxford, Oxford, UK.
Polishchuck R; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
De Risi M; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
Sambri I; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.; Medical Genetics Unit, Department of Medical and Translational Science, Federico II University, Naples, Italy.
Soldati C; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
Seabra MC; CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal.
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Źródło:
Traffic (Copenhagen, Denmark) [Traffic] 2022 May; Vol. 23 (5), pp. 238-269. Date of Electronic Publication: 2022 Apr 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Lysosomes*/metabolism
Metabolic Networks and Pathways*
Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chronically shortened rod outer segments accompany photoreceptor cell death in Choroideremia.
Autorzy:
Meschede IP; UCL Institute of Ophthalmology, London, United Kingdom.
Burgoyne T; UCL Institute of Ophthalmology, London, United Kingdom.
Tolmachova T; Imperial College London, London, United Kingdom.
Seabra MC; UCL Institute of Ophthalmology, London, United Kingdom.; Imperial College London, London, United Kingdom.; CEDOC, NOVA Universidade Nova de Lisboa, Lisbon, Portugal.
Futter CE; UCL Institute of Ophthalmology, London, United Kingdom.
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Źródło:
PloS one [PLoS One] 2020 Nov 17; Vol. 15 (11), pp. e0242284. Date of Electronic Publication: 2020 Nov 17 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Choroideremia/*pathology
Photoreceptor Cells, Vertebrate/*metabolism
Rod Cell Outer Segment/*metabolism
Adaptor Proteins, Signal Transducing/deficiency ; Adaptor Proteins, Signal Transducing/genetics ; Animals ; Choroideremia/metabolism ; Disease Models, Animal ; Female ; Mice ; Mice, Knockout ; Microscopy, Electron, Transmission ; Mitochondria/metabolism ; Photoreceptor Cells, Vertebrate/ultrastructure ; Rhodopsin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.
Autorzy:
Jones S; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, Paul O'Gorman Building, University College London, London, WC1E 6DD, UK.
King PJ; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, Paul O'Gorman Building, University College London, London, WC1E 6DD, UK.
Antonescu CN; Department of Cell Biology, Ryerson University, Toronto, Canada.
Sugiyama MG; Department of Cell Biology, Ryerson University, Toronto, Canada.
Bhamra A; Proteomics Research Core Facility, UCL Cancer Institute, University College London, London, UK.
Surinova S; Proteomics Research Core Facility, UCL Cancer Institute, University College London, London, UK.
Angelopoulos N; Proteomics Research Core Facility, UCL Cancer Institute, University College London, London, UK.
Kragh M; Symphogen A/S, Ballerup, Denmark.
Pedersen MW; Symphogen A/S, Ballerup, Denmark.
Hartley JA; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, Paul O'Gorman Building, University College London, London, WC1E 6DD, UK.
Futter CE; UCL Institute of Ophthalmology, University College London, 11-43 Bath Street, London, EC1V 9EL, UK.
Hochhauser D; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, Paul O'Gorman Building, University College London, London, WC1E 6DD, UK. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jan 20; Vol. 10 (1), pp. 663. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies*
Antineoplastic Agents*
Protein Transport*
Antibodies, Monoclonal/*pharmacology
Endocytosis/*drug effects
Cell Membrane/metabolism ; Cells, Cultured ; DNA-Binding Proteins ; Endosomal Sorting Complexes Required for Transport ; Endosomes/metabolism ; ErbB Receptors/metabolism ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/etiology ; Head and Neck Neoplasms/metabolism ; Humans ; Lysosomes/metabolism ; Phosphoproteins ; Receptors, Cell Surface ; Transcription Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Correlative light and immuno-electron microscopy of retinal tissue cryostat sections.
Autorzy:
Burgoyne T; Institute of Ophthalmology, University College London, London, United Kingdom.; Primary Ciliary Dyskinesia Service, Electron Microscopy Unit, Department of Paediatrics, Royal Brompton Hospital, Sydney Street, London, United Kingdom.
Lane A; Institute of Ophthalmology, University College London, London, United Kingdom.
Laughlin WE; Institute of Ophthalmology, University College London, London, United Kingdom.
Cheetham ME; Institute of Ophthalmology, University College London, London, United Kingdom.
Futter CE; Institute of Ophthalmology, University College London, London, United Kingdom.
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Źródło:
PloS one [PLoS One] 2018 Jan 09; Vol. 13 (1), pp. e0191048. Date of Electronic Publication: 2018 Jan 09 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Light*
Microscopy, Immunoelectron/*methods
Retina/*ultrastructure
Animals ; Mice ; Mice, Inbred C57BL ; Retina/cytology ; Tomography, Optical Coherence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers.
Autorzy:
Stefan CJ; MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London, WC1E 6BT, UK. .
Trimble WS; Cell Biology Program, The Hospital for Sick Children and Department of Biochemistry, University of Toronto, Toronto, Canada. .
Grinstein S; Cell Biology Program, The Hospital for Sick Children and Department of Biochemistry, University of Toronto, Toronto, Canada. .
Drin G; Université Côte d'Azur, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France. .
Reinisch K; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 06520, USA. .
De Camilli P; Department of Neuroscience and Cell Biology, Howard Hughes Medical Institute, Kavli Institute for Neuroscience and Program in Cellular Neuroscience, Neurodegeneration, and Repair, Yale University School of Medicine, New Haven, CT, 06510, USA. .
Cohen S; NICHD, NIH, Bethesda, MD, USA.
Valm AM; NICHD, NIH, Bethesda, MD, USA.
Lippincott-Schwartz J; HHMI Janelia Research Campus, Ashburn, VA, USA. .
Levine TP; UCL Institute of Ophthalmology, 11-43 Bath Street, London, EC1V 9EL, UK. .
Iaea DB; Genentech, 1 DNA Way, South San Francisco, CA, 94080, USA.
Maxfield FR; Department of Biochemistry, Weill Cornell Medical College, 1300 York Ave, New York, NY, 10065, USA. .
Futter CE; UCL Institute of Ophthalmology, 11-43 Bath Street, London, EC1V 9EL, UK. c.futter@ucl.ac.uk.
Eden ER; UCL Institute of Ophthalmology, 11-43 Bath Street, London, EC1V 9EL, UK. .
Judith D; Molecular Cell Biology of Autophagy Laboratory, The Francis Crick Institute, London, UK.
van Vliet AR; Molecular Cell Biology of Autophagy Laboratory, The Francis Crick Institute, London, UK.; Laboratory of Cell Death Research and Therapy, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Agostinis P; Laboratory of Cell Death Research and Therapy, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Tooze SA; Molecular Cell Biology of Autophagy Laboratory, The Francis Crick Institute, London, UK. .
Sugiura A; Kobe University Graduate School of Medicine, 1-5-6 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
McBride HM; Montreal Neurological Institute, McGill University, 3801 University Avenue, Montreal, Quebec, H3A 2B4, Canada. .
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Źródło:
BMC biology [BMC Biol] 2017 Oct 31; Vol. 15 (1), pp. 102. Date of Electronic Publication: 2017 Oct 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Cycle*
Lipid Metabolism*
Organelle Biogenesis*
Biological Transport ; Cell Membrane/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.
Autorzy:
Willén K; Department of Experimental Medical Science, Lund University, 221 84, Lund, Sweden.
Edgar JR; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK.; UCL Institute of Ophthalmology, London, EC1V 9EL, UK.
Hasegawa T; Division of Neurology, Department of Neuroscience and Sensory Organs, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan.
Tanaka N; Division of Cancer Biology and Therapeutics, Miyagi Cancer Center Research Institute, Natori, 981-1293, Japan.
Futter CE; UCL Institute of Ophthalmology, London, EC1V 9EL, UK.
Gouras GK; Department of Experimental Medical Science, Lund University, 221 84, Lund, Sweden. .
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2017 Aug 23; Vol. 12 (1), pp. 61. Date of Electronic Publication: 2017 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Amyloid beta-Protein Precursor/*metabolism
Endosomes/*metabolism
Lysosomes/*metabolism
Multivesicular Bodies/*pathology
Plaque, Amyloid/*pathology
ATPases Associated with Diverse Cellular Activities/metabolism ; Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Animals ; Endosomal Sorting Complexes Required for Transport/metabolism ; Mice, Transgenic ; Neurons/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Host cell autophagy contributes to Plasmodium liver development.
Autorzy:
Thieleke-Matos C; CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056, Lisboa, Portugal.; Instituto Gulbenkian de Ciência, 2780-156, Oeiras, Portugal.
Lopes da Silva M; CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056, Lisboa, Portugal.; Instituto Gulbenkian de Ciência, 2780-156, Oeiras, Portugal.
Cabrita-Santos L; CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056, Lisboa, Portugal.; Instituto Gulbenkian de Ciência, 2780-156, Oeiras, Portugal.
Portal MD; CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056, Lisboa, Portugal.
Rodrigues IP; CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056, Lisboa, Portugal.
Zuzarte-Luis V; Malaria Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028, Lisboa, Portugal.
Ramalho JS; CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056, Lisboa, Portugal.
Futter CE; Institute of Ophthalmology, University College London, London, EC1V 9EL, UK.
Mota MM; Malaria Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028, Lisboa, Portugal.
Barral DC; CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056, Lisboa, Portugal.
Seabra MC; CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056, Lisboa, Portugal.; Instituto Gulbenkian de Ciência, 2780-156, Oeiras, Portugal.; Molecular Medicine Section, National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
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Źródło:
Cellular microbiology [Cell Microbiol] 2016 Mar; Vol. 18 (3), pp. 437-50. Date of Electronic Publication: 2015 Nov 04.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy/*physiology
Host-Parasite Interactions/*physiology
Liver/*parasitology
Malaria/*pathology
Plasmodium berghei/*pathogenicity
Animals ; Apoptosis Regulatory Proteins/metabolism ; Beclin-1 ; Liver/pathology ; Malaria/parasitology ; Mice, Inbred C57BL ; Mice, Transgenic ; Microtubule-Associated Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Leber congenital amaurosis protein AIPL1 and EB proteins co-localize at the photoreceptor cilium.
Autorzy:
Hidalgo-de-Quintana J; Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom.
Schwarz N; Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom.
Meschede IP; Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom.
Stern-Schneider G; Cell and Matrix Biology, Institute of Zoology, Johannes Gutenberg University of Mainz, Mainz, Germany.
Powner MB; Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom.
Morrison EE; Section of Ophthalmology and Neuroscience, Leeds Institute of Molecular Medicine, St James's University Hospital, Leeds, United Kingdom.
Futter CE; Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom.
Wolfrum U; Cell and Matrix Biology, Institute of Zoology, Johannes Gutenberg University of Mainz, Mainz, Germany.
Cheetham ME; Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom.
van der Spuy J; Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom.
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Źródło:
PloS one [PLoS One] 2015 Mar 23; Vol. 10 (3), pp. e0121440. Date of Electronic Publication: 2015 Mar 23 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carrier Proteins/*metabolism
Eye Proteins/*metabolism
Leber Congenital Amaurosis/*metabolism
Microtubule-Associated Proteins/*metabolism
Photoreceptor Cells/*metabolism
Adaptor Proteins, Signal Transducing ; Animals ; Carrier Proteins/genetics ; Cells, Cultured ; Eye Proteins/genetics ; Humans ; Mice ; Microtubules/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Hrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesicles.
Autorzy:
Edgar JR; UCL Institute of Ophthalmology, 11-43 Bath Street, London, EC1V 9EL, UK; Current address: Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 OXY, UK.
Eden ER
Futter CE
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Źródło:
Traffic (Copenhagen, Denmark) [Traffic] 2014 Feb; Vol. 15 (2), pp. 197-211. Date of Electronic Publication: 2014 Jan 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endosomal Sorting Complexes Required for Transport/*metabolism
Multivesicular Bodies/*metabolism
Phosphoproteins/*metabolism
Tetraspanin 30/*metabolism
Epidermal Growth Factor/pharmacology ; HeLa Cells ; Humans ; Multivesicular Bodies/drug effects ; Multivesicular Bodies/ultrastructure ; Protein Transport ; gp100 Melanoma Antigen/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Conditional ablation of the choroideremia gene causes age-related changes in mouse retinal pigment epithelium.
Autorzy:
Wavre-Shapton ST; Molecular Medicine Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Tolmachova T
Lopes da Silva M
Futter CE
Seabra MC
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Źródło:
PloS one [PLoS One] 2013; Vol. 8 (2), pp. e57769. Date of Electronic Publication: 2013 Feb 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Deletion*
Adaptor Proteins, Signal Transducing/*genetics
Aging/*pathology
Retinal Pigment Epithelium/*metabolism
Retinal Pigment Epithelium/*pathology
Adaptor Proteins, Signal Transducing/metabolism ; Aging/metabolism ; Animals ; Bruch Membrane/metabolism ; Bruch Membrane/pathology ; Bruch Membrane/ultrastructure ; Extracellular Space/metabolism ; Integrases/metabolism ; Intracellular Space/metabolism ; Lipofuscin/metabolism ; Melanosomes/metabolism ; Melanosomes/ultrastructure ; Mice ; Mice, Inbred C57BL ; Phagosomes/metabolism ; Phagosomes/ultrastructure ; Protein Transport ; Retinal Pigment Epithelium/ultrastructure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The host endocytic pathway is essential for Plasmodium berghei late liver stage development.
Autorzy:
Lopes da Silva M; CEDOC, Faculdade de Ciências Médicas, FCM, Universidade Nova de Lisboa, Lisboa, 1169-056, Portugal; Instituto Gulbenkian de Ciência, Oeiras, 2780-156, Portugal.
Thieleke-Matos C
Cabrita-Santos L
Ramalho JS
Wavre-Shapton ST
Futter CE
Barral DC
Seabra MC
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Źródło:
Traffic (Copenhagen, Denmark) [Traffic] 2012 Oct; Vol. 13 (10), pp. 1351-63. Date of Electronic Publication: 2012 Aug 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endocytosis*
Host-Parasite Interactions*
Hepatocytes/*metabolism
Hepatocytes/*parasitology
Plasmodium berghei/*growth & development
Plasmodium berghei/*metabolism
Animals ; Cytoplasmic Vesicles/chemistry ; Female ; Lysosomal Membrane Proteins/analysis ; Mice ; Mice, Inbred C57BL ; Schizonts/growth & development ; Tetraspanin 30/analysis ; Tumor Cells, Cultured ; rab GTP-Binding Proteins/analysis ; rab7 GTP-Binding Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The role of EGF receptor ubiquitination in regulating its intracellular traffic.
Autorzy:
Eden ER; UCL Institute of Ophthalmology, University College London, 11-43 Bath Street, London, EC1V 9EL, UK.
Huang F
Sorkin A
Futter CE
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Źródło:
Traffic (Copenhagen, Denmark) [Traffic] 2012 Feb; Vol. 13 (2), pp. 329-37. Date of Electronic Publication: 2011 Nov 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
ErbB Receptors/*metabolism
Protein Transport/*physiology
Ubiquitination/*physiology
Animals ; Aorta/cytology ; Cell Membrane/metabolism ; Cells, Cultured ; Clathrin/genetics ; Clathrin/metabolism ; Endosomal Sorting Complexes Required for Transport/metabolism ; Endosomes/metabolism ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Epidermal Growth Factor/metabolism ; Epidermal Growth Factor/pharmacology ; ErbB Receptors/genetics ; Humans ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Multivesicular Bodies/drug effects ; Multivesicular Bodies/metabolism ; Multivesicular Bodies/ultrastructure ; Mutation/physiology ; Phosphorylation/drug effects ; Protein Binding/drug effects ; Protein Binding/physiology ; Protein Subunits/metabolism ; Protein Transport/drug effects ; Sus scrofa ; Transfection ; Transferrin/metabolism ; Vesicular Transport Proteins/genetics ; Vesicular Transport Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4.
Autorzy:
Qureshi OS; Medical Research Council (MRC) Centre for Immune Regulation, School of Immunity and Infection, Institute of Biomedical Research, University of Birmingham Medical School, Birmingham B15 2TT, UK.
Zheng Y
Nakamura K
Attridge K
Manzotti C
Schmidt EM
Baker J
Jeffery LE
Kaur S
Briggs Z
Hou TZ
Futter CE
Anderson G
Walker LS
Sansom DM
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Źródło:
Science (New York, N.Y.) [Science] 2011 Apr 29; Vol. 332 (6029), pp. 600-3. Date of Electronic Publication: 2011 Apr 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endocytosis*
Antigens, CD/*immunology
B7-1 Antigen/*immunology
B7-2 Antigen/*immunology
CD28 Antigens/*immunology
T-Lymphocyte Subsets/*immunology
Animals ; Antigens, CD/metabolism ; B7-1 Antigen/metabolism ; B7-2 Antigen/metabolism ; CHO Cells ; CTLA-4 Antigen ; Cricetinae ; Cricetulus ; Dendritic Cells/immunology ; Humans ; Jurkat Cells ; Ligands ; Lymphocyte Activation ; Mice ; Mice, Transgenic ; Models, Biological ; Ovalbumin/immunology ; Receptors, Antigen, T-Cell/immunology ; Recombinant Fusion Proteins/metabolism ; T-Lymphocyte Subsets/metabolism ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Annexins and endocytosis.
Autorzy:
Futter CE; Institute of Ophthalmology, University College, London, 11-43 Bath Street, London EC1V 9EL, UK. c.futter@ucl.ac.uk
White IJ
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Źródło:
Traffic (Copenhagen, Denmark) [Traffic] 2007 Aug; Vol. 8 (8), pp. 951-8. Date of Electronic Publication: 2007 Jun 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Annexins/*physiology
Endocytosis/*physiology
Animals ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 22

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