Temat: "G1 Phase Cell Cycle Checkpoints" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: BMP7 regulates lung fibroblast proliferation in newborn rats with bronchopulmonary dysplasia.
Autorzy:: Sun Y; Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Fu J; Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Xue X; Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Yang H; Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Wu L; Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 May; Vol. 17 (5), pp. 6277-6284. Date of Electronic Publication: 2018 Mar 07.
Typ publikacji:: Journal Article
MeSH Terms:: G1 Phase Cell Cycle Checkpoints*
Bone Morphogenetic Protein 7/*biosynthesis
Bronchopulmonary Dysplasia/*metabolism
Fibroblasts/*metabolism
Pulmonary Alveoli/*metabolism
Animals ; Animals, Newborn ; Bronchopulmonary Dysplasia/pathology ; Fibroblasts/pathology ; Gene Expression Regulation ; Pulmonary Alveoli/pathology ; Rats ; Rats, Wistar

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Skocz do pozycji: 2.

Tytuł:: shRNA-mediated RPS15A silencing inhibits U937 acute myeloid leukemia cell proliferation and enhances apoptosis.
Autorzy:: Li G; Department of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Zhang L; Department of Hematology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China.
Liu J; Department of Hematology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China.
Xiao T; Department of Hematology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China.
Liu G; Department of Hematology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China.
Wang J; Department of Hematology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China.
Hou M; Department of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2016 May; Vol. 13 (5), pp. 4400-6. Date of Electronic Publication: 2016 Mar 30.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
G1 Phase Cell Cycle Checkpoints*
Gene Silencing*
Resting Phase, Cell Cycle*
Leukemia, Myeloid, Acute/*metabolism
Neoplasm Proteins/*antagonists & inhibitors
RNA, Small Interfering/*biosynthesis
Ribosomal Proteins/*antagonists & inhibitors
Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Leukemia, Myeloid, Acute/therapy ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; RNA, Small Interfering/genetics ; Ribosomal Proteins/biosynthesis ; Ribosomal Proteins/genetics ; U937 Cells

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Skocz do pozycji: 3.

Tytuł:: Inhibition of WWP2 suppresses proliferation, and induces G1 cell cycle arrest and apoptosis in liver cancer cells.
Autorzy:: Xu SQ; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Qin Y; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Pan DB; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Ye GX; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Wu CJ; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Wang S; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Jiang JY; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Fu J; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Wang CJ; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2016 Mar; Vol. 13 (3), pp. 2261-6. Date of Electronic Publication: 2016 Jan 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*/genetics
G1 Phase Cell Cycle Checkpoints*/genetics
Liver Neoplasms/*pathology
Ubiquitin-Protein Ligases/*metabolism
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/metabolism ; Blotting, Western ; Cell Line, Tumor ; Cell Proliferation ; Cell Survival/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Liver Neoplasms/genetics ; Male ; Middle Aged ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction/genetics ; Ubiquitin-Protein Ligases/genetics ; Up-Regulation/genetics

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Skocz do pozycji: 4.

Tytuł:: Silencing of MAP4K4 by short hairpin RNA suppresses proliferation, induces G1 cell cycle arrest and induces apoptosis in gastric cancer cells.
Autorzy:: Liu YF; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China.
Qu GQ; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China.
Lu YM; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China.
Kong WM; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China.
Liu Y; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China.
Chen WX; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China.
Liao XH; Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2016 Jan; Vol. 13 (1), pp. 41-8. Date of Electronic Publication: 2015 Nov 06.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*/genetics
G1 Phase Cell Cycle Checkpoints*/genetics
Gene Silencing*
Intracellular Signaling Peptides and Proteins/*metabolism
Protein Serine-Threonine Kinases/*metabolism
RNA, Small Interfering/*metabolism
Stomach Neoplasms/*enzymology
Stomach Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Cell Line, Tumor ; Cell Proliferation ; Down-Regulation/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness ; RNA Interference ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Notch/metabolism ; Signal Transduction/genetics ; Stomach Neoplasms/genetics ; bcl-2-Associated X Protein/metabolism

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Skocz do pozycji: 5.

Tytuł:: miR‑296‑3p promotes the proliferation of glioblastoma cells by targeting ICAT.
Autorzy:: Zhou J; Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Du G; Department of Oncology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.
Fu H; Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2020 May; Vol. 21 (5), pp. 2151-2161. Date of Electronic Publication: 2020 Mar 03.
Typ publikacji:: Journal Article
MeSH Terms:: Adaptor Proteins, Signal Transducing/*metabolism
Brain Neoplasms/*metabolism
Cell Proliferation/*genetics
Gene Expression Regulation, Neoplastic/*genetics
Glioblastoma/*metabolism
MicroRNAs/*metabolism
Wnt Signaling Pathway/*genetics
3' Untranslated Regions ; Adaptor Proteins, Signal Transducing/genetics ; Apoptosis/genetics ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Cell Differentiation/genetics ; Cell Line, Tumor ; Cyclin D1/genetics ; Cyclin D1/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Down-Regulation ; G1 Phase Cell Cycle Checkpoints/genetics ; Gene Silencing ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; MicroRNAs/genetics ; Neoplasm Grading ; Up-Regulation

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Skocz do pozycji: 6.

Tytuł:: Suppression of CLEC3A inhibits osteosarcoma cell proliferation and promotes their chemosensitivity through the AKT1/mTOR/HIF1α signaling pathway.
Autorzy:: Ren C; Department of Orthopedics, Guiyang Maternal and Child Health-Care Hospital, Guiyang, Guizhou 550000, P.R. China.
Pan R; Department of Orthopedics, Guiyang Maternal and Child Health-Care Hospital, Guiyang, Guizhou 550000, P.R. China.
Hou L; Department of Orthopedics, Guiyang Maternal and Child Health-Care Hospital, Guiyang, Guizhou 550000, P.R. China.
Wu H; Department of Orthopedics, Guiyang Maternal and Child Health-Care Hospital, Guiyang, Guizhou 550000, P.R. China.
Sun J; Department of Orthopedics, Guiyang Maternal and Child Health-Care Hospital, Guiyang, Guizhou 550000, P.R. China.
Zhang W; Department of Orthopedics, Guiyang Maternal and Child Health-Care Hospital, Guiyang, Guizhou 550000, P.R. China.
Tian X; Department of Orthopedics, Clinical Medical College of Guizhou Medical University, Guiyang, Guizhou 550000, P.R. China.
Chen H; Department of Orthopedics, Guiyang Maternal and Child Health-Care Hospital, Guiyang, Guizhou 550000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2020 Apr; Vol. 21 (4), pp. 1739-1748. Date of Electronic Publication: 2020 Feb 13.
Typ publikacji:: Journal Article
MeSH Terms:: Signal Transduction*/drug effects
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Lectins, C-Type/*metabolism
Osteosarcoma/*drug therapy
Osteosarcoma/*pathology
TOR Serine-Threonine Kinases/*metabolism
Adolescent ; Adult ; Aged ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Child ; Cisplatin/pharmacology ; Doxorubicin/pharmacology ; Female ; G1 Phase Cell Cycle Checkpoints/drug effects ; Humans ; Inhibitory Concentration 50 ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Staging ; Osteosarcoma/metabolism ; Proto-Oncogene Proteins c-akt/metabolism

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Skocz do pozycji: 7.

Tytuł:: Long non‑coding RNA H19 protects H9c2 cells against hypoxia‑induced injury by activating the PI3K/AKT and ERK/p38 pathways.
Autorzy:: Yuan L; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Yu L; Department of Thyroid Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Zhang J; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Zhou Z; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Li C; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Zhou B; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Hu X; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Xu G; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Tang Y; Department of Cardiac Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2020 Apr; Vol. 21 (4), pp. 1709-1716. Date of Electronic Publication: 2020 Feb 06.
Typ publikacji:: Journal Article
MeSH Terms:: MAP Kinase Signaling System*
Cytoprotection/*genetics
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
RNA, Long Noncoding/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Animals ; Apoptosis/genetics ; Cell Hypoxia/genetics ; Cell Line ; G1 Phase Cell Cycle Checkpoints/genetics ; Gene Expression Regulation ; Membrane Potential, Mitochondrial ; RNA, Long Noncoding/genetics ; Rats

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Skocz do pozycji: 8.

Tytuł:: Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF‑κB/COX‑2/PPAR‑γ activities.
Autorzy:: Wang Z; Department of Basic Medicine, Qujing Medical College, Qujing, Yunnan 655000, P.R. China.
Li F; Department of Basic Medicine, Qujing Medical College, Qujing, Yunnan 655000, P.R. China.
Quan Y; School of Nursing, Qujing Medical College, Qujing, Yunnan 655000, P.R. China.
Shen J; Department of Traditional Chinese Medicine, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, Zhejiang 315000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 Jun; Vol. 19 (6), pp. 5417-5423. Date of Electronic Publication: 2019 Apr 25.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2/*metabolism
Flavonoids/*pharmacology
Gene Expression Regulation, Neoplastic/*drug effects
NF-kappa B/*metabolism
PPAR gamma/*metabolism
Apoptosis/drug effects ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cyclooxygenase 2/genetics ; Drugs, Chinese Herbal/pharmacology ; Flavonoids/chemistry ; G1 Phase Cell Cycle Checkpoints/drug effects ; Humans ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; NF-kappa B/genetics ; PPAR gamma/genetics

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Skocz do pozycji: 9.

Tytuł:: MicroRNA‑486‑5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression.
Autorzy:: Shi Y; Department of Decorative Plastic Surgery, The Eighth People's Hospital of Shanghai, Jiangsu University, Shanghai 200233, P.R. China.
Wang L; Department of Decorative Plastic Surgery, The Eighth People's Hospital of Shanghai, Jiangsu University, Shanghai 200233, P.R. China.
Yu P; Department of Decorative Plastic Surgery, The Eighth People's Hospital of Shanghai, Jiangsu University, Shanghai 200233, P.R. China.
Liu Y; Department of Decorative Plastic Surgery, The Eighth People's Hospital of Shanghai, Jiangsu University, Shanghai 200233, P.R. China.
Chen W; Department of Decorative Plastic Surgery, The Eighth People's Hospital of Shanghai, Jiangsu University, Shanghai 200233, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 Jun; Vol. 19 (6), pp. 5203-5210. Date of Electronic Publication: 2019 Apr 24.
Typ publikacji:: Journal Article
MeSH Terms:: Cicatrix, Hypertrophic/*pathology
MicroRNAs/*metabolism
Smad2 Protein/*metabolism
3' Untranslated Regions ; Adult ; Antagomirs/metabolism ; Apoptosis ; Cell Proliferation ; Cicatrix, Hypertrophic/metabolism ; Cyclin-Dependent Kinase 2/metabolism ; Cyclin-Dependent Kinase 4/metabolism ; Female ; Fibroblasts/cytology ; Fibroblasts/metabolism ; G1 Phase Cell Cycle Checkpoints ; Humans ; Male ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/genetics ; Middle Aged ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Smad2 Protein/chemistry ; Smad2 Protein/genetics ; bcl-2-Associated X Protein/metabolism

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Skocz do pozycji: 10.

Tytuł:: Bergapten induces G1 arrest of non‑small cell lung cancer cells, associated with the p53‑mediated cascade.
Autorzy:: Chiang SR; Department of Internal Medicine, Chi Mei Medical Center, Tainan 710, Taiwan, R.O.C.
Lin CS; Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung 402, Taiwan, R.O.C.
Lin HH; Surgical Department, Cardiovascular Division, China Medical University Hospital, Taichung 402, Taiwan, R.O.C.
Shieh PC; Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung 402, Taiwan, R.O.C.
Kao SH; Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung 402, Taiwan, R.O.C.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2019 Mar; Vol. 19 (3), pp. 1972-1978. Date of Electronic Publication: 2019 Jan 02.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung/*drug therapy
Cyclin D1/*genetics
Cyclin-Dependent Kinase 4/*genetics
Tumor Suppressor Protein p53/*genetics
5-Methoxypsoralen/pharmacology ; A549 Cells ; Apoptosis/drug effects ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; G1 Phase Cell Cycle Checkpoints/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Signal Transduction/drug effects

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Skocz do pozycji: 11.

Tytuł:: Silencing of perilipin by short hairpin RNA inhibits proliferation and induces apoptosis in liposarcoma cells.
Autorzy:: Meng LX; Department of Oncology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China.
Zheng YX; Department of Oncology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China.
He ML; Department of Oncology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China.
Zhou XM; Department of Oncology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China.
Sun SY; Department of Pathology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China.
Ding ZJ; Department of Oncology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China.
Meng Q; Department of Oncology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China.
Li BC; Department of Oncology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China.
Sun YW; Department of Oncology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Nov; Vol. 18 (5), pp. 4571-4576. Date of Electronic Publication: 2018 Sep 05.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Proliferation/*genetics
Liposarcoma/*genetics
Perilipin-1/*genetics
RNA, Small Interfering/*genetics
Apoptosis/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Flow Cytometry ; G1 Phase Cell Cycle Checkpoints/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Liposarcoma/pathology ; Perilipin-1/antagonists & inhibitors ; RNA Interference

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Skocz do pozycji: 12.

Tytuł:: Low‑frequency ultrasound and microbubbles combined with simvastatin promote the apoptosis of MCF‑7 cells by affecting the LATS1/YAP/RHAMM pathway.
Autorzy:: Li H; Department of Imaging, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, P.R. China.
Chen C; Department of Imaging, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, P.R. China.
Wang D; Department of Imaging, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Sep; Vol. 18 (3), pp. 2724-2732. Date of Electronic Publication: 2018 Jul 12.
Typ publikacji:: Journal Article
MeSH Terms:: Microbubbles*
Apoptosis/*drug effects
Signal Transduction/*drug effects
Simvastatin/*pharmacology
Adaptor Proteins, Signal Transducing/metabolism ; Extracellular Matrix Proteins/metabolism ; G1 Phase Cell Cycle Checkpoints/drug effects ; Humans ; Hyaluronan Receptors/metabolism ; Kruppel-Like Transcription Factors/metabolism ; MCF-7 Cells ; Phosphoproteins/metabolism ; Protein Serine-Threonine Kinases/metabolism ; Sonication ; Transcription Factors ; YAP-Signaling Proteins

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Skocz do pozycji: 13.

Tytuł:: Downregulation of microRNA‑21 expression inhibits proliferation, and induces G1 arrest and apoptosis via the PTEN/AKT pathway in SKM‑1 cells.
Autorzy:: Li G; Institute of Hematopathy, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.
Song Y; Institute of Hematopathy, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.
Li G; Institute of Hematopathy, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.
Ren J; Institute of Hematopathy, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.
Xie J; Institute of Hematopathy, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.
Zhang Y; Institute of Hematopathy, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.
Gao F; Institute of Hematopathy, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.
Mu J; Institute of Hematopathy, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.
Dai J; Institute of Hematopathy, Xi'an Central Hospital, Xi'an, Shaanxi 710003, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Sep; Vol. 18 (3), pp. 2771-2779. Date of Electronic Publication: 2018 Jul 05.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Cell Proliferation*
MicroRNAs/*metabolism
PTEN Phosphohydrolase/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Antagomirs/metabolism ; Caspase 3/metabolism ; Cell Line, Tumor ; Cyclin D1/metabolism ; Down-Regulation ; G1 Phase Cell Cycle Checkpoints ; Humans ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/genetics ; Myelodysplastic Syndromes/metabolism ; Myelodysplastic Syndromes/pathology ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA Interference ; RNA, Small Interfering/metabolism ; Signal Transduction ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism

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Skocz do pozycji: 14.

Tytuł:: Induction of apoptosis by Bigelovii A through inhibition of NF‑κB activity.
Autorzy:: Guan F; College of Life Science, Nanjing Agricultural University, Nanjing, Jiangsu 210095, P.R. China.
Shan Y; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Jiangsu Key Laboratory for The Research and Uti1ization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu 210014, P.R. China.
Wang Q; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Jiangsu Key Laboratory for The Research and Uti1ization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu 210014, P.R. China.
Wang M; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Jiangsu Key Laboratory for The Research and Uti1ization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu 210014, P.R. China.
Chen Y; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Jiangsu Key Laboratory for The Research and Uti1ization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu 210014, P.R. China.
Yin M; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Jiangsu Key Laboratory for The Research and Uti1ization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu 210014, P.R. China.
Liu F; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Jiangsu Key Laboratory for The Research and Uti1ization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu 210014, P.R. China.
Zhao Y; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Jiangsu Key Laboratory for The Research and Uti1ization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu 210014, P.R. China.
Zhang J; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Jiangsu Key Laboratory for The Research and Uti1ization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu 210014, P.R. China.
Feng X; College of Life Science, Nanjing Agricultural University, Nanjing, Jiangsu 210095, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Aug; Vol. 18 (2), pp. 1600-1608. Date of Electronic Publication: 2018 May 30.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Chenopodiaceae/*chemistry
NF-kappa B/*genetics
Saponins/*pharmacology
Triterpenes/*pharmacology
Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis/genetics ; Caspases/genetics ; Caspases/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cyclin D1/genetics ; Cyclin D1/metabolism ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Female ; G1 Phase Cell Cycle Checkpoints/drug effects ; Humans ; MCF-7 Cells ; NF-KappaB Inhibitor alpha/antagonists & inhibitors ; NF-KappaB Inhibitor alpha/genetics ; NF-KappaB Inhibitor alpha/metabolism ; NF-kappa B/antagonists & inhibitors ; NF-kappa B/metabolism ; Phosphorylation/drug effects ; Poly(ADP-ribose) Polymerases/genetics ; Poly(ADP-ribose) Polymerases/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Saponins/isolation & purification ; Signal Transduction ; Triterpenes/isolation & purification ; bcl-X Protein/genetics ; bcl-X Protein/metabolism

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Skocz do pozycji: 15.

Tytuł:: Sevoflurane suppresses proliferation by upregulating microRNA-203 in breast cancer cells.
Autorzy:: Liu J; Department of Anesthesiology, The Second Clinical College of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Yang L; Department of Anesthesiology, Huangshi Central Hospital, Huangshi, Hubei 435000, P.R. China.
Guo X; Department of Ophthalmology, Third People's Hospital of Jinan, Jinan, Shandong 250100, P.R. China.
Jin G; Department of Anesthesiology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan 450007, P.R. China.
Wang Q; Department of Anesthesiology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan 450007, P.R. China.
Lv D; Department of Anesthesiology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan 450007, P.R. China.
Liu J; Department of Anesthesiology, The Second Clinical College of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Chen Q; Department of Anesthesiology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan 450007, P.R. China.
Song Q; Department of Anesthesiology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan 450007, P.R. China.
Li B; Department of Anesthesiology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan 450007, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Jul; Vol. 18 (1), pp. 455-460. Date of Electronic Publication: 2018 May 03.
Typ publikacji:: Journal Article
MeSH Terms:: Breast Neoplasms/*metabolism
G1 Phase Cell Cycle Checkpoints/*drug effects
Gene Expression Regulation, Neoplastic/*drug effects
Methyl Ethers/*pharmacology
MicroRNAs/*biosynthesis
RNA, Neoplasm/*biosynthesis
Signal Transduction/*drug effects
Up-Regulation/*drug effects
Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Cell Line, Tumor ; Female ; Humans ; MicroRNAs/genetics ; RNA, Neoplasm/genetics ; Sevoflurane ; Signal Transduction/genetics

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Skocz do pozycji: 16.

Tytuł:: Serum starvation-induces down-regulation of Bcl-2/Bax confers apoptosis in tongue coating-related cells in vitro.
Autorzy:: Huang Y; Department of Stomatology, Nanjing Maternity and Child Health Medical Institute, Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Fu Z; Department of Stomatology, Nanjing Maternity and Child Health Medical Institute, Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Dong W; Department of Pathogen and Immunology, Discipline of Chinese and Western Integrative Medicine, College of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, P.R. China.
Zhang Z; Department of Pathogen and Immunology, Discipline of Chinese and Western Integrative Medicine, College of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, P.R. China.
Mu J; Department of Stomatology, Ningbo Dental Hospital, Ningbo, Zhejiang 315100, P.R. China.
Zhang J; Department of Pathogen and Immunology, Discipline of Chinese and Western Integrative Medicine, College of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210023, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Apr; Vol. 17 (4), pp. 5057-5064. Date of Electronic Publication: 2018 Jan 29.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation*
Apoptosis/*genetics
Epithelial Cells/*metabolism
Proto-Oncogene Proteins c-bcl-2/*genetics
Tongue/*cytology
bcl-2-Associated X Protein/*genetics
Cell Proliferation/genetics ; Cells, Cultured ; Epithelial Cells/ultrastructure ; Flow Cytometry ; G1 Phase Cell Cycle Checkpoints/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2-Associated X Protein/metabolism

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Skocz do pozycji: 17.

Tytuł:: Investigation of the neuroprotective effects of Lycium barbarum water extract in apoptotic cells and Alzheimer's disease mice.
Autorzy:: Hu X; Faculty of Clinical Medicine, Changchun Medical College, Changchun, Jilin 130031, P.R. China.
Qu Y; School of Life Sciences, Jilin University, Changchun, Jilin 130012, P.R. China.
Chu Q; School of Life Sciences, Jilin University, Changchun, Jilin 130012, P.R. China.
Li W; School of Life Sciences, Jilin University, Changchun, Jilin 130012, P.R. China.
He J; School of Life Sciences, Jilin University, Changchun, Jilin 130012, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Mar; Vol. 17 (3), pp. 3599-3606. Date of Electronic Publication: 2017 Dec 19.
Typ publikacji:: Journal Article
MeSH Terms:: Alzheimer Disease/*drug therapy
Lycium/*chemistry
Neuroprotective Agents/*therapeutic use
Plant Extracts/*chemistry
Acetylcholine/metabolism ; Alzheimer Disease/pathology ; Animals ; Apoptosis/drug effects ; Calcium/metabolism ; Cell Survival/drug effects ; Choline O-Acetyltransferase/blood ; Choline O-Acetyltransferase/metabolism ; Disease Models, Animal ; G1 Phase Cell Cycle Checkpoints/drug effects ; Hypothalamus/metabolism ; Lycium/metabolism ; Male ; Maze Learning/drug effects ; Mice ; Mice, Inbred C57BL ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/pharmacology ; PC12 Cells ; Rats ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 18.

Tytuł:: Therapeutic effects of β-elemene via attenuation of the Wnt/β-catenin signaling pathway in cervical cancer cells.
Autorzy:: Wang L; Department of Gynecology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110000, P.R. China.
Zhao Y; Department of Gynecology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110000, P.R. China.
Wu Q; Department of Gynecology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110000, P.R. China.
Guan Y; Department of Biochemistry and Molecular Biology, China Medical University, Shenyang, Liaoning 110000, P.R. China.
Wu X; Department of Gynecology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Mar; Vol. 17 (3), pp. 4299-4306. Date of Electronic Publication: 2018 Jan 18.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Antineoplastic Agents, Phytogenic/*pharmacology
G1 Phase Cell Cycle Checkpoints/*drug effects
Sesquiterpenes/*pharmacology
Signal Transduction/*drug effects
beta Catenin/*genetics
Antineoplastic Agents, Phytogenic/isolation & purification ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Curcuma/chemistry ; Cyclin D1/antagonists & inhibitors ; Cyclin D1/genetics ; Cyclin D1/metabolism ; Cyclin-Dependent Kinase Inhibitor p15/agonists ; Cyclin-Dependent Kinase Inhibitor p15/genetics ; Cyclin-Dependent Kinase Inhibitor p15/metabolism ; Drugs, Chinese Herbal ; HeLa Cells ; Humans ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 9/metabolism ; Proto-Oncogene Proteins c-bcl-2/antagonists & inhibitors ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-myc/antagonists & inhibitors ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; Sesquiterpenes/isolation & purification ; Signal Transduction/genetics ; T Cell Transcription Factor 1/antagonists & inhibitors ; T Cell Transcription Factor 1/genetics ; T Cell Transcription Factor 1/metabolism ; Tumor Suppressor Protein p53/agonists ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; bcl-2-Associated X Protein/agonists ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; beta Catenin/antagonists & inhibitors ; beta Catenin/metabolism

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Skocz do pozycji: 19.

Tytuł:: Suppression of human breast cancer cells by tectorigenin through downregulation of matrix metalloproteinases and MAPK signaling in vitro.
Autorzy:: Zeng L; Department of Surgery, Tinglin Hospital of Jinshan District, Shanghai 201505, P.R. China.
Yuan S; Department of Surgery, Tinglin Hospital of Jinshan District, Shanghai 201505, P.R. China.
Shen J; Department of Surgery, Tinglin Hospital of Jinshan District, Shanghai 201505, P.R. China.
Wu M; Department of Surgery, Tinglin Hospital of Jinshan District, Shanghai 201505, P.R. China.
Pan L; Department of Surgery, Tinglin Hospital of Jinshan District, Shanghai 201505, P.R. China.
Kong X; Department of Surgery, Tinglin Hospital of Jinshan District, Shanghai 201505, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Mar; Vol. 17 (3), pp. 3935-3943. Date of Electronic Publication: 2017 Dec 19.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Antineoplastic Agents, Phytogenic/*pharmacology
Isoflavones/*pharmacology
Matrix Metalloproteinase 2/*genetics
Matrix Metalloproteinase 9/*genetics
Mitogen-Activated Protein Kinases/*genetics
Apoptosis/drug effects ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Line ; Cell Line, Tumor ; Cell Migration Assays ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Female ; G1 Phase Cell Cycle Checkpoints/drug effects ; Humans ; MCF-7 Cells ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/metabolism ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/metabolism ; Mitogen-Activated Protein Kinases/antagonists & inhibitors ; Mitogen-Activated Protein Kinases/metabolism ; Poly(ADP-ribose) Polymerases/genetics ; Poly(ADP-ribose) Polymerases/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Signal Transduction

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Skocz do pozycji: 20.

Tytuł:: Liposome‑delivered baicalein induction of myeloid leukemia K562 cell death via reactive oxygen species generation.
Autorzy:: Wang SX; Department of Natural Sciences, Faculty of Science and Technology, Middlesex University, London NW4 4BT, UK.
Wen X; Department of Natural Sciences, Faculty of Science and Technology, Middlesex University, London NW4 4BT, UK.
Bell C; Department of Natural Sciences, Faculty of Science and Technology, Middlesex University, London NW4 4BT, UK.
Appiah S; Department of Natural Sciences, Faculty of Science and Technology, Middlesex University, London NW4 4BT, UK.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Mar; Vol. 17 (3), pp. 4524-4530. Date of Electronic Publication: 2018 Jan 08.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Flavanones/*pharmacology
Liposomes/*chemistry
Reactive Oxygen Species/*metabolism
Cell Proliferation/drug effects ; Flavanones/chemistry ; G1 Phase Cell Cycle Checkpoints/drug effects ; Humans ; K562 Cells

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