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Wyszukujesz frazę ""GAP-43 Protein"" wg kryterium: Temat


Tytuł :
Dl-3-n-butylphthalide promotes neurite outgrowth of primary cortical neurons by Sonic Hedgehog signaling via upregulating Gap43.
Autorzy :
Zhang C; Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China; Hebei Key Laboratory of Vascular Homeostasis and Hebei Collaborative Innovation Center for Cardio-cerebrovascular Disease, Shijiazhuang, Hebei, China.
Cui L; Department of Neurology, Second Hospital of Hebei Medical University; Shijiazhuang, Hebei, China; Hebei Key Laboratory of Vascular Homeostasis and Hebei Collaborative Innovation Center for Cardio-cerebrovascular Disease, Shijiazhuang, Hebei, China.
He W; Department of Neurology, Hebei General Hospital, Shijiazhuang, Hebei, China.
Zhang X; Department of Neurology, Second Hospital of Hebei Medical University; Shijiazhuang, Hebei, China; Hebei Key Laboratory of Vascular Homeostasis and Hebei Collaborative Innovation Center for Cardio-cerebrovascular Disease, Shijiazhuang, Hebei, China.
Liu H; Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2021 Jan 15; Vol. 398 (2), pp. 112420. Date of Electronic Publication: 2020 Dec 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzofurans/*pharmacology
GAP-43 Protein/*metabolism
Hedgehog Proteins/*metabolism
Neurons/*drug effects
Up-Regulation/*drug effects
Animals ; Cell Survival/drug effects ; Cells, Cultured ; Female ; GAP-43 Protein/genetics ; Mice ; Mice, Inbred C57BL ; Neuronal Outgrowth/drug effects ; Neuronal Plasticity/drug effects ; Neurons/metabolism ; Pregnancy ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Transcriptome profiling unveils GAP43 regulates ABC transporters and EIF2 signaling in colorectal cancer cells.
Autorzy :
Chen X; School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150001, China.
Wu H; Department of Clinical Laboratory, Hangzhou Cancer Hospital, Hangzhou,, 320000, Zhejiang, China.; The NHC Key Laboratory of Drug Addition Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, 650000, China.
Feng J; School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150001, China.
Li Y; School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150001, China.
Lv J; School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150001, China.
Shi W; School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150001, China.
Fan W; Department of Infectious and Medicine, Heilongjiang Provincial Hospital, Harbin, 150036, China.
Xiao L; School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150001, China.
Sun D; Department of Pediatrics, Data People's hospital, Shenmu, 719301, China.
Jiang M; Department of Clinical Laboratory, Hangzhou Cancer Hospital, Hangzhou,, 320000, Zhejiang, China. .
Shi M; School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150001, China. .
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Źródło :
BMC cancer [BMC Cancer] 2021 Jan 05; Vol. 21 (1), pp. 24. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Methylation*
Gene Expression Regulation, Neoplastic*
ATP-Binding Cassette Transporters/*metabolism
Biomarkers, Tumor/*metabolism
Colorectal Neoplasms/*pathology
Eukaryotic Initiation Factor-2/*metabolism
GAP-43 Protein/*metabolism
ATP-Binding Cassette Transporters/genetics ; Apoptosis ; Biomarkers, Tumor/genetics ; Cell Proliferation ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Eukaryotic Initiation Factor-2/genetics ; GAP-43 Protein/genetics ; Gene Regulatory Networks ; Humans ; Prognosis ; Promoter Regions, Genetic ; Transcriptome ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Carbamazepine conquers spinal GAP43 deficiency and sciatic Nav1.5 upregulation in diabetic mice: novel mechanisms in alleviating allodynia and hyperalgesia.
Autorzy :
El-Sherbeeny NA; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ring Road, Ismailia, 41522, Egypt. .
Ibrahiem AT; Department of Pathology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Ali HS; Department of Pharmacology, Faculty of Medicine, Assuit University, Assuit, Egypt.; Department of Pharmacology, Faculty of Medicine, University of Tabuk, Tabuk, Saudi Arabia.
Farag NE; Department of Physiology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.; Department of Physiology, College of Medicine, Taif University, Taif, Saudi Arabia.
Toraih EA; Department of Histology and Cell Biology (Genetics Unit), Faculty of Medicine, Suez Canal University, Ismailia, Egypt.; Department of Surgery, School of Medicine, Tulane University, New Orleans, LA, USA.
Zaitone SA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia.
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Źródło :
Archives of pharmacal research [Arch Pharm Res] 2020 Jul; Vol. 43 (7), pp. 724-734. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Carbamazepine/*pharmacology
Diabetes Mellitus, Experimental/*drug therapy
Diabetic Neuropathies/*drug therapy
GAP-43 Protein/*metabolism
NAV1.5 Voltage-Gated Sodium Channel/*metabolism
Spinal Cord/*drug effects
Alloxan/administration & dosage ; Animals ; Carbamazepine/administration & dosage ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/pathology ; Diabetic Neuropathies/metabolism ; Diabetic Neuropathies/pathology ; Disease Models, Animal ; Dose-Response Relationship, Drug ; GAP-43 Protein/genetics ; Hyperalgesia ; Injections, Intraperitoneal ; Male ; Mice ; NAV1.5 Voltage-Gated Sodium Channel/genetics ; Spinal Cord/chemistry ; Spinal Cord/metabolism
Czasopismo naukowe
Tytuł :
The antibiotic doxycycline mimics the NGF signaling in PC12 cells: A relevant mechanism for neuroprotection.
Autorzy :
Amaral LD; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USP, Av Do Café S/n, 14040-903, Ribeirão Preto, SP, Brazil.
Santos NAGD; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USP, Av Do Café S/n, 14040-903, Ribeirão Preto, SP, Brazil.
Sisti FM; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USP, Av Do Café S/n, 14040-903, Ribeirão Preto, SP, Brazil.
Del Bel E; Departamento de Morfologia, Estomatologia e Fisiologia, Faculdade de Odontologia de Ribeirão Preto - USP, 14040-904, Ribeirão Preto, SP, Brazil.
Santos ACD; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USP, Av Do Café S/n, 14040-903, Ribeirão Preto, SP, Brazil. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 May 25; Vol. 341, pp. 109454. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Doxycycline/*pharmacology
Nerve Growth Factor/*metabolism
Animals ; Carbazoles/pharmacology ; Cell Survival/drug effects ; GAP-43 Protein/metabolism ; Indole Alkaloids/pharmacology ; MAP Kinase Signaling System/drug effects ; Nerve Growth Factor/pharmacology ; Neurofilament Proteins/metabolism ; Neuronal Outgrowth/drug effects ; Neuroprotective Agents/pharmacology ; PC12 Cells ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Receptor, trkA/antagonists & inhibitors ; Receptor, trkA/metabolism ; Signal Transduction/drug effects ; Synapsins/metabolism
Czasopismo naukowe
Tytuł :
Effects of combination treatment with transcranial magnetic stimulation and bone marrow mesenchymal stem cell transplantation or Raf inhibition on spinal cord injury in rats.
Autorzy :
Feng S; Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Wang S; Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Sun S; Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Su H; Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Zhang L; Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Apr; Vol. 23 (4). Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Marrow Transplantation/*methods
Indoles/*pharmacology
Mesenchymal Stem Cell Transplantation/*methods
Spinal Cord Injuries/*therapy
Sulfonamides/*pharmacology
Transcranial Magnetic Stimulation/*methods
raf Kinases/*antagonists & inhibitors
Animals ; Brain-Derived Neurotrophic Factor/metabolism ; Cells, Cultured ; Combined Modality Therapy ; Disease Models, Animal ; Female ; GAP-43 Protein/metabolism ; Glial Fibrillary Acidic Protein/metabolism ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/metabolism ; Motor Activity/drug effects ; Rats, Sprague-Dawley ; Recovery of Function/drug effects ; Spinal Cord Injuries/metabolism ; Spinal Cord Injuries/physiopathology ; raf Kinases/metabolism
Czasopismo naukowe
Tytuł :
PtdIns4P-mediated electrostatic forces influence S-acylation of peripheral proteins at the Golgi complex.
Autorzy :
Chumpen Ramirez S; CONICET. Universidad Nacional de Córdoba, Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC), Córdoba, Argentina.; Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Química Biológica Ranwel Caputto, Córdoba, Argentina.
Astrada MR; CONICET. Universidad Nacional de Córdoba, Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC), Córdoba, Argentina.; Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Química Biológica Ranwel Caputto, Córdoba, Argentina.
Daniotti JL; CONICET. Universidad Nacional de Córdoba, Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC), Córdoba, Argentina.; Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Departamento de Química Biológica Ranwel Caputto, Córdoba, Argentina.
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Źródło :
Bioscience reports [Biosci Rep] 2020 Jan 31; Vol. 40 (1).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Processing, Post-Translational*
Disks Large Homolog 4 Protein/*metabolism
GAP-43 Protein/*metabolism
Phosphatidylinositol Phosphates/*metabolism
trans-Golgi Network/*metabolism
Acylation ; Amino Acid Motifs ; Amino Acid Sequence ; Animals ; CHO Cells ; Conserved Sequence ; Cricetulus ; Disks Large Homolog 4 Protein/chemistry ; Disks Large Homolog 4 Protein/genetics ; GAP-43 Protein/chemistry ; GAP-43 Protein/genetics ; Hydrophobic and Hydrophilic Interactions ; Static Electricity ; Time Factors ; trans-Golgi Network/genetics
Czasopismo naukowe
Tytuł :
GAP-43 is involved in the orientation of cell division by interacting with GΑI during neurogenesis.
Autorzy :
Huang R; Institute of Central Laboratory, Capital Institute of Pediatrics, Beijing, China.; Department of Neurobiology, Beijing Institute for Brain Disorders, Beijing Center of Neural Regeneration and Repair, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Capital Medical University, Beijing, China.
Xiao H; Institute of Central Laboratory, Capital Institute of Pediatrics, Beijing, China.; Graduate School of Peking Union Medical College, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.
Zhao J; Department of Neurobiology, Beijing Institute for Brain Disorders, Beijing Center of Neural Regeneration and Repair, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Capital Medical University, Beijing, China.
Ju L; Department of Neurobiology, Beijing Institute for Brain Disorders, Beijing Center of Neural Regeneration and Repair, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Capital Medical University, Beijing, China.
Wen Y; Department of Neurobiology, Beijing Institute for Brain Disorders, Beijing Center of Neural Regeneration and Repair, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Capital Medical University, Beijing, China.; Ningxia Key Laboratory of Cerebrocranial Diseases, Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China.
Xu Q; Department of Neurobiology, Beijing Institute for Brain Disorders, Beijing Center of Neural Regeneration and Repair, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Capital Medical University, Beijing, China.
Cui X; Institute of Central Laboratory, Capital Institute of Pediatrics, Beijing, China.
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Źródło :
The International journal of neuroscience [Int J Neurosci] 2020 Feb; Vol. 130 (2), pp. 144-152. Date of Electronic Publication: 2019 Sep 26.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*growth & development
Cell Division/*physiology
GAP-43 Protein/*physiology
GTP-Binding Protein alpha Subunits/*metabolism
Neurogenesis/*physiology
Animals ; Brain/metabolism ; Embryo, Mammalian ; GAP-43 Protein/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Inactivation of GAP-43 due to the depletion of cellular calcium by the Pb and amyloid peptide induced toxicity: An in vitro approach.
Autorzy :
Ayyalasomayajula N; Department of Cell and Molecular Biology, National Institute of Nutrition (ICMR), Hyderabad, India.
Bandaru M; Department of Cell and Molecular Biology, National Institute of Nutrition (ICMR), Hyderabad, India.
Dixit PK; Berhampur University, Berhampur, India.
Ajumeera R; Department of Cell and Molecular Biology, National Institute of Nutrition (ICMR), Hyderabad, India.
Chetty CS; Savannah State University, GA, USA.
Challa S; Department of Cell and Molecular Biology, National Institute of Nutrition (ICMR), Hyderabad, India. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2020 Jan 25; Vol. 316, pp. 108927. Date of Electronic Publication: 2019 Dec 13.
Typ publikacji :
Journal Article
MeSH Terms :
Amyloid beta-Peptides/*toxicity
Calcium/*metabolism
GAP-43 Protein/*metabolism
Gene Expression Regulation/*drug effects
Lead/*toxicity
Amyloid Precursor Protein Secretases/genetics ; Amyloid Precursor Protein Secretases/metabolism ; Aspartic Acid Endopeptidases/genetics ; Aspartic Acid Endopeptidases/metabolism ; Cell Differentiation/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; GAP-43 Protein/genetics ; Humans ; Protein Kinase C/genetics ; Protein Kinase C/metabolism ; Synaptophysin/genetics ; Synaptophysin/metabolism
Czasopismo naukowe
Tytuł :
Urokinase-type plasminogen activator (uPA) regulates the expression and function of growth-associated protein 43 (GAP-43) in the synapse.
Autorzy :
Merino P; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329-4208.
Diaz A; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329-4208.
Torre ER; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329-4208.
Yepes M; Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Atlanta, Georgia 30329-4208; Department of Neurology and Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, Georgia 30322-0001; Department of Neurology, Veterans Affairs Medical Center, Atlanta, Georgia 30033-4004. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Jan 10; Vol. 295 (2), pp. 619-630. Date of Electronic Publication: 2019 Dec 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
GAP-43 Protein/*metabolism
Synapses/*metabolism
Urokinase-Type Plasminogen Activator/*metabolism
Animals ; Cells, Cultured ; Cerebral Cortex/cytology ; Cerebral Cortex/metabolism ; GAP-43 Protein/analysis ; Mice ; Neurons/cytology ; Neurons/metabolism ; Phosphorylation ; Receptors, N-Methyl-D-Aspartate/analysis ; Receptors, N-Methyl-D-Aspartate/metabolism ; Urokinase-Type Plasminogen Activator/analysis
Czasopismo naukowe
Tytuł :
[Effect of moxibustion on expression of GAP-43 in sciatic nerve trunk and ventral horn of spinal cord of rats with primary sciatica and its nerve repair function].
Autorzy :
Wu MM; Department of Geriatrics, Second Affiliated Hospital of Anhui University of CM, Hefei 230000, China.
Zhang LD; Graduate School of Anhui University of CM.
Yang K; Department of Geriatrics, Second Affiliated Hospital of Anhui University of CM, Hefei 230000, China.
Luo XZ; Graduate School of Anhui University of CM.
Tu JF; Department of Acupuncture and Moxibustion, Beijing Hospital of TCM, Capital Medical University.
Cai SC; Department of Geriatrics, Second Affiliated Hospital of Anhui University of CM, Hefei 230000, China.
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Źródło :
Zhongguo zhen jiu = Chinese acupuncture & moxibustion [Zhongguo Zhen Jiu] 2021 Feb 12; Vol. 41 (2), pp. 183-8.
Typ publikacji :
Journal Article
MeSH Terms :
Electroacupuncture*
Moxibustion*
Sciatica*/therapy
Animals ; GAP-43 Protein/genetics ; Male ; Rats ; Rats, Sprague-Dawley ; Sciatic Nerve ; Spinal Cord
Czasopismo naukowe
Tytuł :
Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids.
Autorzy :
Pinto G; Unité de Trafic Membranaire et Pathogenèse, Institut Pasteur, UMR3691 CNRS, 28 rue du Docteur Roux, F-75015 Paris, France.; Sorbonne Université, ED394 - Physiologie, Physiopathologie et Thérapeutique, F-75005 Paris, France.
Saenz-de-Santa-Maria I; Unité de Trafic Membranaire et Pathogenèse, Institut Pasteur, UMR3691 CNRS, 28 rue du Docteur Roux, F-75015 Paris, France.
Chastagner P; Unité de Trafic Membranaire et Pathogenèse, Institut Pasteur, UMR3691 CNRS, 28 rue du Docteur Roux, F-75015 Paris, France.
Perthame E; Hub de Bioinformatique et Biostatistique - Département Biologie Computationnelle, Institut Pasteur, USR 3756 CNRS, F-75015 Paris, France.
Delmas C; Cancer Research Center of Toulouse (CRCT), Institut National de la Santé et de la Recherche Médicale (INSERM), UMR 1037, Institut Claudius Regaud, Université Toulouse III Paul Sabatier, Toulouse F-31000, France.
Toulas C; Cancer Research Center of Toulouse (CRCT), Institut National de la Santé et de la Recherche Médicale (INSERM), UMR 1037, Institut Claudius Regaud, Université Toulouse III Paul Sabatier, Toulouse F-31000, France.
Moyal-Jonathan-Cohen E; Cancer Research Center of Toulouse (CRCT), Institut National de la Santé et de la Recherche Médicale (INSERM), UMR 1037, Institut Claudius Regaud, Université Toulouse III Paul Sabatier, Toulouse F-31000, France.
Brou C; Unité de Trafic Membranaire et Pathogenèse, Institut Pasteur, UMR3691 CNRS, 28 rue du Docteur Roux, F-75015 Paris, France.
Zurzolo C; Unité de Trafic Membranaire et Pathogenèse, Institut Pasteur, UMR3691 CNRS, 28 rue du Docteur Roux, F-75015 Paris, France.
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Źródło :
The Biochemical journal [Biochem J] 2021 Jan 15; Vol. 478 (1), pp. 21-39.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Communication*
Brain Neoplasms/*metabolism
Cell Surface Extensions/*metabolism
Glioblastoma/*metabolism
Mitochondria/*metabolism
Neoplastic Stem Cells/*metabolism
Organoids/*metabolism
Brain Neoplasms/pathology ; Cell Line, Tumor ; Cell Surface Extensions/pathology ; Cells, Cultured ; Disease Progression ; GAP-43 Protein/metabolism ; Glioblastoma/pathology ; Humans ; Mitochondria/pathology ; Neoplastic Stem Cells/pathology ; Neoplastic Stem Cells/radiation effects ; Organoids/pathology ; Radiation ; Recurrence ; Time-Lapse Imaging
Czasopismo naukowe
Tytuł :
Growth-associated protein 43 promotes thyroid cancer cell lines progression via epithelial-mesenchymal transition.
Autorzy :
Zheng C; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Quan RD; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Wu CY; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Hu J; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Lin BY; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Dong XB; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Xia EJ; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Bhandari A; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Zhang XH; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Wang OC; Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Dec; Vol. 23 (12), pp. 7974-7984. Date of Electronic Publication: 2019 Sep 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphatic Metastasis*
Cell Proliferation/*genetics
Epithelial-Mesenchymal Transition/*genetics
GAP-43 Protein/*metabolism
Thyroid Cancer, Papillary/*metabolism
Thyroid Neoplasms/*metabolism
Adult ; Apoptosis/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cohort Studies ; Databases, Genetic ; Female ; GAP-43 Protein/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Gene Knockdown Techniques ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness/genetics ; Neoplasm Staging ; RNA, Small Interfering ; Risk Factors ; Thyroid Cancer, Papillary/genetics ; Thyroid Cancer, Papillary/pathology ; Thyroid Neoplasms/genetics ; Thyroid Neoplasms/pathology ; Thyroid Neoplasms/secondary
Czasopismo naukowe
Tytuł :
Cerebrospinal fluid growth-associated protein 43 in multiple sclerosis.
Autorzy :
Sandelius Å; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Sandgren S; Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. .
Axelsson M; Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Malmeström C; Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Novakova L; Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Kostanjevecki V; Fujirebio Europe NV, Ghent, Belgium.
Vandijck M; Fujirebio Europe NV, Ghent, Belgium.
Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom.; UK Dementia Research Institute at UCL, London, United Kingdom.
Lycke J; Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
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Źródło :
Scientific reports [Sci Rep] 2019 Nov 21; Vol. 9 (1), pp. 17309. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
GAP-43 Protein/*cerebrospinal fluid
Multiple Sclerosis, Chronic Progressive/*diagnosis
Multiple Sclerosis, Relapsing-Remitting/*diagnosis
Nerve Regeneration/*immunology
Adult ; Biomarkers/cerebrospinal fluid ; Case-Control Studies ; Disease Progression ; Enzyme-Linked Immunosorbent Assay ; Female ; Follow-Up Studies ; GAP-43 Protein/immunology ; Healthy Volunteers ; Humans ; Male ; Multiple Sclerosis, Chronic Progressive/cerebrospinal fluid ; Multiple Sclerosis, Chronic Progressive/immunology ; Multiple Sclerosis, Chronic Progressive/therapy ; Multiple Sclerosis, Relapsing-Remitting/cerebrospinal fluid ; Multiple Sclerosis, Relapsing-Remitting/immunology ; Multiple Sclerosis, Relapsing-Remitting/therapy ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Neuroprotective effect of levetiracetam in mouse diabetic retinopathy: Effect on glucose transporter-1 and GAP43 expression.
Autorzy :
Mohammad HMF; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt; Central Lab., Center of Excellence in Molecular and Cellular Medicine (CEMCM), Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Sami MM; Department of Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Makary S; Department of Medical Physiology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Toraih EA; Genetics Unit, Department of Histology and Cell Biology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt; Molecular Lab, Center of Excellence of Molecular and Cellular Medicine, Suez Canal University, Ismailia, Egypt.
Mohamed AO; Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt.
El-Ghaiesh SH; Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt; Department of Pharmacology, Faculty of Medicine, University of Tabuk, Tabuk, Saudi Arabia. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2019 Sep 01; Vol. 232, pp. 116588. Date of Electronic Publication: 2019 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetic Retinopathy/*drug therapy
Diabetic Retinopathy/*metabolism
GAP-43 Protein/*biosynthesis
Glucose Transporter Type 1/*biosynthesis
Levetiracetam/*pharmacology
Animals ; Blood Glucose/metabolism ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/drug therapy ; Diabetes Mellitus, Experimental/metabolism ; Diabetic Retinopathy/blood ; Diabetic Retinopathy/genetics ; Disease Models, Animal ; GAP-43 Protein/genetics ; Glucose Transporter Type 1/genetics ; Immunohistochemistry ; Inflammation/metabolism ; Interleukin-6/metabolism ; Male ; Mice ; NF-kappa B/metabolism ; Neuroprotective Agents/pharmacology ; Nitric Oxide Synthase Type II/metabolism ; Retina/metabolism ; Retinal Diseases/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Neuritin-overexpressing transgenic mice demonstrate enhanced neuroregeneration capacity and improved spatial learning and memory recovery after ischemia-reperfusion injury.
Autorzy :
Wan K; Department of Biochemistry, College of Medicine, Shihezi University, Shihezi 832000, Xinjiang, China.
Mao F; Department of Biochemistry, College of Medicine, Shihezi University, Shihezi 832000, Xinjiang, China.
Li Q; Department of Biochemistry, College of Medicine, Shihezi University, Shihezi 832000, Xinjiang, China.
Wang L; State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Sciences, Shihezi 832000, Xinjiang, China.
Wei Z; College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471023, Henan, China.
Wang P; College of Animal Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, Henan, China.
Liao X; First Affiliated Hospital, Medical College, Shihezi University, Shihezi 832000, Xinjiang, China.
Xu M; State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Sciences, Shihezi 832000, Xinjiang, China.
Huang J; Department of Biochemistry, College of Medicine, Shihezi University, Shihezi 832000, Xinjiang, China.
Pan Z; Department of Biochemistry, College of Medicine, Shihezi University, Shihezi 832000, Xinjiang, China.
Wang C; Department of Biochemistry, College of Medicine, Shihezi University, Shihezi 832000, Xinjiang, China.
Luo J; State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Sciences, Shihezi 832000, Xinjiang, China.
Gao R; Department of Biochemistry, College of Medicine, Shihezi University, Shihezi 832000, Xinjiang, China.
Gan S; State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Sciences, Shihezi 832000, Xinjiang, China.
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Źródło :
Aging [Aging (Albany NY)] 2020 Dec 15; Vol. 13 (2), pp. 2681-2699. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Memory*
Spatial Learning*
Brain/*physiopathology
Brain Regeneration/*genetics
Neurons/*metabolism
Neuropeptides/*genetics
Reperfusion Injury/*physiopathology
Animals ; Apoptosis ; Brain/blood supply ; Brain/metabolism ; Carotid Artery, Common ; Cell Survival ; Female ; GAP-43 Protein/metabolism ; GPI-Linked Proteins/genetics ; GPI-Linked Proteins/metabolism ; Hippocampus/cytology ; Hippocampus/metabolism ; Male ; Mice ; Mice, Transgenic ; Morris Water Maze Test ; Neurofilament Proteins/metabolism ; Neuropeptides/metabolism ; Poly (ADP-Ribose) Polymerase-1/metabolism ; RNA, Messenger/metabolism ; Rats ; Recovery of Function ; Reperfusion Injury/metabolism ; Synaptophysin/metabolism
Czasopismo naukowe
Tytuł :
Effects of repetitive magnetic stimulation on motor function and GAP43 and 5-HT expression in rats with spinal cord injury.
Autorzy :
Liu H; Department of Rehabilitation, Shanghai Fourth People's Hospital Affiliated with Tongji University School of Medicine, Shanghai, P.R. China.; Department of Rehabilitation, The First Affiliated Hospital of Naval Medical University, Shanghai, P.R. China.
Xiong D; Department of Rehabilitation, The Second People's Hospital of Yibin, Yibin, Sichuan, P.R. China.
Pang R; Department of Rehabilitation, The General Hospital of Western Theater Command, Chengdu, Sichuan, P.R. China.
Deng Q; School of Medicine, Southwest Jiaotong University, Chengdu, Sichuan, P.R. China.
Sun N; Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning, P.R. China.
Zheng J; Department of Rehabilitation, The General Hospital of Western Theater Command, Chengdu, Sichuan, P.R. China.
Liu J; Department of Rehabilitation, The General Hospital of Western Theater Command, Chengdu, Sichuan, P.R. China.
Xiang W; Department of Rehabilitation, The General Hospital of Western Theater Command, Chengdu, Sichuan, P.R. China.
Chen Z; Department of Rehabilitation, The General Hospital of Western Theater Command, Chengdu, Sichuan, P.R. China.
Lu J; Department of Rehabilitation, Chengdu Eighth People's Hospital, Chengdu, Sichuan, P.R. China.
Wang W; Department of Rehabilitation, The General Hospital of Western Theater Command, Chengdu, Sichuan, P.R. China.
Zhang A; Department of Rehabilitation, Shanghai Fourth People's Hospital Affiliated with Tongji University School of Medicine, Shanghai, P.R. China.
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Źródło :
The Journal of international medical research [J Int Med Res] 2020 Dec; Vol. 48 (12), pp. 300060520970765.
Typ publikacji :
Journal Article
MeSH Terms :
Serotonin*
Spinal Cord Injuries*/therapy
Animals ; Apoptosis ; Disease Models, Animal ; GAP-43 Protein/genetics ; Magnetic Phenomena ; Nogo Proteins ; Rats ; Rats, Sprague-Dawley ; Recovery of Function ; Spinal Cord
Czasopismo naukowe
Tytuł :
RVG29-modified microRNA-loaded nanoparticles improve ischemic brain injury by nasal delivery.
Autorzy :
Hao R; Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, ChangChun, Jilin, China.
Sun B; School of Pharmaceutical Sciences, Jilin University, ChangChun, Jilin, China.
Yang L; Affiliated Hospital of Changchun University of Chinese medicine, ChangChun, Jilin, China.
Ma C; Affiliated Hospital of Changchun University of Chinese medicine, ChangChun, Jilin, China.
Li S; Affiliated Hospital of Changchun University of Chinese medicine, ChangChun, Jilin, China.
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Źródło :
Drug delivery [Drug Deliv] 2020 Dec; Vol. 27 (1), pp. 772-781.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*drug effects
Brain Ischemia/*drug therapy
Drug Carriers/*chemistry
Glycoproteins/*chemistry
MicroRNAs/*administration & dosage
Nanoparticles/*chemistry
Peptide Fragments/*chemistry
Polyesters/*chemistry
Polyethylene Glycols/*chemistry
Viral Proteins/*chemistry
Administration, Intranasal ; Animals ; Brain/metabolism ; Brain Ischemia/metabolism ; Disease Models, Animal ; GAP-43 Protein/genetics ; Gene Expression/drug effects ; MicroRNAs/pharmacokinetics ; MicroRNAs/therapeutic use ; Particle Size ; Rats, Sprague-Dawley ; Surface Properties ; rho GTP-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
Spontaneous Neuronal Plasticity in the Contralateral Motor Cortex and Corticospinal Tract after Focal Cortical Infarction in Hypertensive Rats.
Autorzy :
Huang X; Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China.
Wang X; Department of Neurology, Wuzhou Red Cross Hospital, Wuzhou, Guangxi Zhuang Autonomous Region 543002, China.
Yang M; Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China.
Pan X; Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China.
Duan M; Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China.
Wen X; Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China.
Cai H; Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China.
Jiang G; Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China.
Chen L; Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China; Guangxi Key Laboratory of Regenerative Medicine and Guangxi Collaborative Innovation Center for Biomedicine, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Dec; Vol. 29 (12), pp. 105235. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article
MeSH Terms :
Motor Activity*
Neuronal Plasticity*
Forelimb/*innervation
Hypertension, Renovascular/*complications
Infarction, Middle Cerebral Artery/*physiopathology
Motor Cortex/*physiopathology
Pyramidal Tracts/*physiopathology
Animals ; Blood Pressure ; Disease Models, Animal ; GAP-43 Protein/metabolism ; Hypertension, Renovascular/physiopathology ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/metabolism ; Male ; Motor Cortex/metabolism ; Pyramidal Tracts/metabolism ; Rats, Sprague-Dawley ; Recovery of Function ; Synaptophysin/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Methylene blue promotes survival and GAP-43 expression of retinal ganglion cells after optic nerve transection.
Autorzy :
Fung JCL; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China. Electronic address: .
Cho EYP; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
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Źródło :
Life sciences [Life Sci] 2020 Dec 01; Vol. 262, pp. 118462. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article
MeSH Terms :
GAP-43 Protein/*genetics
Methylene Blue/*pharmacology
Neuroprotective Agents/*pharmacology
Optic Nerve Injuries/*drug therapy
Retinal Ganglion Cells/*drug effects
Animals ; Axons ; Cell Survival/drug effects ; Cricetinae ; Disease Models, Animal ; Female ; Intravitreal Injections ; Methylene Blue/administration & dosage ; Nerve Regeneration/drug effects ; Neuroprotective Agents/administration & dosage ; Optic Nerve/drug effects ; Optic Nerve/pathology ; Optic Nerve Injuries/physiopathology ; Retinal Ganglion Cells/cytology ; Time Factors
Czasopismo naukowe
Tytuł :
Effect of Vitamin B Complex Treatment on Macrophages to Schwann Cells Association during Neuroinflammation after Peripheral Nerve Injury.
Autorzy :
Ehmedah A; Institute of Physiology and Biochemistry 'Ivan Djaja', Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia.
Nedeljkovic P; Institute for Orthopedic Surgery 'Banjica', 11000 Belgrade, Serbia.
Dacic S; Institute of Physiology and Biochemistry 'Ivan Djaja', Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia.
Repac J; Institute of Physiology and Biochemistry 'Ivan Djaja', Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia.
Draskovic-Pavlovic B; Institute for Medical Research, Military Medical Academy, 11000 Belgrade, Serbia.
Vučević D; Institute for Medical Research, Military Medical Academy, 11000 Belgrade, Serbia.
Pekovic S; Department of Neurobiology, Institute for Biological Research 'Sinisa Stankovic', National Institute of Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.
Nedeljkovic BB; Institute of Physiology and Biochemistry 'Ivan Djaja', Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia.; Institute for Medical Research, Military Medical Academy, 11000 Belgrade, Serbia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Nov 19; Vol. 25 (22). Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
MeSH Terms :
Inflammation/*pathology
Macrophages/*pathology
Peripheral Nerve Injuries/*pathology
Schwann Cells/*pathology
Vitamin B Complex/*pharmacology
Animals ; Anti-Inflammatory Agents/pharmacology ; Cell Communication/drug effects ; Femoral Nerve/drug effects ; Femoral Nerve/pathology ; Femoral Nerve/physiopathology ; GAP-43 Protein ; Inflammation Mediators/metabolism ; Interleukin-10/pharmacology ; Macrophages/drug effects ; Male ; Peripheral Nerve Injuries/physiopathology ; Rats ; Recovery of Function/drug effects ; Schwann Cells/drug effects ; Tumor Necrosis Factor-alpha/metabolism ; Vitamin B Complex/administration & dosage
Czasopismo naukowe

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