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Tytuł :
Multi-omics analysis of the prognosis and therapeutic significance of circadian clock in ovarian cancer.
Autorzy :
Zhu J; Department of Gynecology, Maoming People's Hospital, Maoming, Guangdong 525000, China.
Zhou Q; Department of Gynecology, Huazhou Traditional Chinese Medicine Hospital, Maoming, Guangdong 525000, China.
Pan M; Department of Gynecology, Maoming People's Hospital, Maoming, Guangdong 525000, China. Electronic address: .
Zhou C; Department of Gynecology, Southern Medical University Affiliated Maternal & Child Health Hospital of Foshan, Foshan, Guangdong 528000, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jul 01; Vol. 788, pp. 145644. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Circadian Rhythm Signaling Peptides and Proteins/*genetics
Gene Expression Profiling/*methods
Ovarian Neoplasms/*genetics
Ovarian Neoplasms/*mortality
Circadian Clocks ; Databases, Genetic ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Prognosis ; Sequence Analysis, RNA ; Survival Analysis ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Identification of hub genes, pathways, and related transcription factors in systemic lupus erythematosus: A preliminary bioinformatics analysis.
Autorzy :
Wang Y; Department of Medical Genetics and Cell Biology, Ningxia Medical University, Key Laboratory of Fertility Preservation and Maintenance, Ministry of Education, Key Laboratory of Reproduction and Heredity of Ningxia Hui Autonomous Region, Yinchuan, Ningxia, PR China.
Ma Q
Huo Z
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Jun 25; Vol. 100 (25), pp. e26499.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Gene Expression Regulation/*immunology
Lupus Erythematosus, Systemic/*genetics
Transcription Factors/*metabolism
Biomarkers/analysis ; Computational Biology ; Datasets as Topic ; Gene Expression Profiling ; Humans ; Lupus Erythematosus, Systemic/immunology ; Oligonucleotide Array Sequence Analysis ; Protein Interaction Mapping ; Protein Interaction Maps/genetics ; Signal Transduction/genetics ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
A unique neurogenomic state emerges after aggressive confrontations in males of the fish Betta splendens.
Autorzy :
Vu TD; School of Pharmacy, Kitasato University, Tokyo, Japan; School of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan; Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan.
Iwasaki Y; Nagahama Institute of Bio-Science and Technology, Nagahama, Japan.
Oshima K; School of Pharmacy, Kitasato University, Tokyo, Japan.
Chiu MT; Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan.
Nikaido M; School of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
Okada N; School of Pharmacy, Kitasato University, Tokyo, Japan; Department of Life Sciences, National Cheng Kung University, Tainan, Taiwan; Nagahama Institute of Bio-Science and Technology, Nagahama, Japan. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jun 05; Vol. 784, pp. 145601. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Aggression/*physiology
Fishes/*physiology
Gene Expression Profiling/*veterinary
Animals ; Behavior, Animal/physiology ; Brain/metabolism ; Fish Proteins/genetics ; Fishes/genetics ; Gene Expression Regulation ; High-Throughput Nucleotide Sequencing ; Male ; Sequence Analysis, RNA ; Territoriality
Czasopismo naukowe
Tytuł :
African Americans and European Americans exhibit distinct gene expression patterns across tissues and tumors associated with immunologic functions and environmental exposures.
Autorzy :
Singh U; Bioinformatics and Computational Biology Program, Iowa State University, Ames, IA, 50011, USA.; Center for Metabolic Biology, Iowa State University, Ames, IA, 50011, USA.; Genetics Development and Cell Biology, Iowa State University, Ames, IA, 50011, USA.
Hernandez KM; Department of Medicine, University of Chicago, Chicago, IL, 60637, USA.; Center for Translational Data Science, University of Chicago, Chicago, IL, 60637, USA.
Aronow BJ; Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
Wurtele ES; Bioinformatics and Computational Biology Program, Iowa State University, Ames, IA, 50011, USA. .; Center for Metabolic Biology, Iowa State University, Ames, IA, 50011, USA. .; Genetics Development and Cell Biology, Iowa State University, Ames, IA, 50011, USA. .
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Źródło :
Scientific reports [Sci Rep] 2021 May 10; Vol. 11 (1), pp. 9905. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Regulation, Neoplastic*
African Americans/*genetics
COVID-19/*genetics
European Continental Ancestry Group/*genetics
Gene Expression Profiling/*methods
Neoplasms/*genetics
COVID-19/epidemiology ; COVID-19/virology ; Chemokine CCL3/genetics ; Gene Regulatory Networks ; Glutathione Transferase/genetics ; Humans ; Neoplasms/classification ; Neoplasms/ethnology ; Nuclear Proteins/genetics ; Pandemics ; Prognosis ; RNA-Seq/methods ; SARS-CoV-2/isolation & purification ; SARS-CoV-2/physiology ; Socioeconomic Factors ; United States/epidemiology
Czasopismo naukowe
Tytuł :
CRISPR-Cas9 editing of non-coding genomic loci as a means of controlling gene expression in the sea urchin.
Autorzy :
Pieplow A; Department of Molecular Biology, Cellular Biology and Biochemistry, Brown University, Providence, RI, 02912, USA.
Dastaw M; Ethiopian Biotechnology Institute, Addis Ababa University, NBH1, 4killo King George VI St, Addis Ababa, Ethiopia.
Sakuma T; Division of Integrated Sciences for Life, Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, 739-8526, Japan.
Sakamoto N; Division of Integrated Sciences for Life, Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, 739-8526, Japan.
Yamamoto T; Division of Integrated Sciences for Life, Graduate School of Integrated Sciences for Life, Hiroshima University, Hiroshima, 739-8526, Japan.
Yajima M; Department of Molecular Biology, Cellular Biology and Biochemistry, Brown University, Providence, RI, 02912, USA.
Oulhen N; Department of Molecular Biology, Cellular Biology and Biochemistry, Brown University, Providence, RI, 02912, USA.
Wessel GM; Department of Molecular Biology, Cellular Biology and Biochemistry, Brown University, Providence, RI, 02912, USA. Electronic address: .
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Źródło :
Developmental biology [Dev Biol] 2021 Apr; Vol. 472, pp. 85-97. Date of Electronic Publication: 2021 Jan 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
CRISPR-Cas Systems*
Gene Expression Regulation, Developmental*
Genetic Loci*
Gene Editing/*methods
Promoter Regions, Genetic/*genetics
Strongylocentrotus purpuratus/*embryology
Strongylocentrotus purpuratus/*genetics
Animals ; Animals, Genetically Modified ; CRISPR-Associated Protein 9/genetics ; Embryo, Nonmammalian/metabolism ; Embryonic Development/genetics ; Gene Expression ; Gene Knockout Techniques ; Germ Cells/metabolism ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Nodal Protein/genetics ; Nodal Protein/metabolism ; RNA, Guide/genetics ; RNA, Messenger/genetics ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Transcription, Genetic/genetics
Czasopismo naukowe
Tytuł :
Profiling transcriptomic changes and signaling pathways in atopic dermatitis by integrative analyses on multiple databases.
Autorzy :
Xu Y; Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000, Zhejiang, China.
Chen S; Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000, Zhejiang, China.
Chen J; Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000, Zhejiang, China. .
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Źródło :
Molecular genetics and genomics : MGG [Mol Genet Genomics] 2021 Mar; Vol. 296 (2), pp. 341-353. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Computational Biology/*methods
Dermatitis, Atopic/*genetics
Dinitrofluorobenzene/*analogs & derivatives
Gene Expression Profiling/*methods
Animals ; Databases, Genetic ; Dermatitis, Atopic/chemically induced ; Dinitrofluorobenzene/adverse effects ; Disease Models, Animal ; Gene Expression Regulation ; Humans ; Male ; Mice ; Protein Interaction Maps ; Signal Transduction
Czasopismo naukowe
Tytuł :
Identification and validation of inferior prognostic genes associated with immune signatures and chemotherapy outcome in acute myeloid leukemia.
Autorzy :
Wang J; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China.; Department of Pharmacy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Hao JP; Department of Hematology, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Uddin MN; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Wu Y; Department of General Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Chen R; Department of Hematology, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Li DF; Department of Pharmacy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Xiong DQ; Department of Pharmacy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Ding N; Department of Pharmacy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Yang JH; Department of Pharmacy, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Ding XS; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
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Źródło :
Aging [Aging (Albany NY)] 2021 Jun 18; Vol. 13 (12), pp. 16445-16470. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Gene Expression Regulation, Leukemic*
Leukemia, Myeloid, Acute/*genetics
Leukemia, Myeloid, Acute/*immunology
Female ; Gene Ontology ; Gene Regulatory Networks ; Genes, Essential ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Male ; Middle Aged ; Prognosis ; Protein Interaction Maps/genetics ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; ROC Curve ; Reproducibility of Results ; Signal Transduction/genetics ; Transcriptome/genetics ; Treatment Outcome ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł :
Transcriptome analysis identifies the differentially expressed genes related to the stemness of limbal stem cells in mice.
Autorzy :
Guo ZH; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China; Stem Cell Laboratory, The Second Affiliated Hospital of Fujian Medical University, China.
Jia YYS; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China.
Zeng YM; The Second Affiliated Hospital of Fujian Medical University, China.
Li ZF; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China.
Lin JS; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Apr 05; Vol. 775, pp. 145447. Date of Electronic Publication: 2021 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Epithelium, Corneal/*chemistry
Gene Expression Profiling/*veterinary
Animals ; Cells, Cultured ; Conjunctiva/chemistry ; Gene Expression Regulation ; High-Throughput Nucleotide Sequencing ; Mice ; Protein Interaction Maps ; Sequence Analysis, RNA ; Stem Cells/chemistry
Czasopismo naukowe
Tytuł :
Integrative genomic expression analysis reveals stable differences between lung cancer and systemic sclerosis.
Autorzy :
Li H; Department of Rheumatology and Immunology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, 518020, China.; Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou, 510632, China.
Ding L; Department of Rheumatology and Immunology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, 518020, China.
Hong X; Department of Rheumatology and Immunology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, 518020, China.
Chen Y; Department of Rheumatology and Immunology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, 518020, China.
Liao R; Department of Rheumatology and Immunology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, 518020, China.
Wang T; Department of Rheumatology and Immunology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, 518020, China.; Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou, 510632, China.
Meng S; Department of Rheumatology and Immunology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, 518020, China.
Jiang Z; Department of Microbiology and Immunology, College of Basic Medicine and Public Hygiene, Jinan University, Guangzhou, 510632, China. .
Liu D; Department of Rheumatology and Immunology, Shenzhen People's Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, 518020, China. .; The First Affiliated Hospital (Shenzhen People's Hospital) Southern University of Science and Technology, Shenzhen, 518055, China. .
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Źródło :
BMC cancer [BMC Cancer] 2021 Mar 10; Vol. 21 (1), pp. 259. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Biomarkers, Tumor/*genetics
Gene Expression Regulation, Neoplastic/*immunology
Lung Neoplasms/*genetics
Scleroderma, Systemic/*genetics
Case-Control Studies ; Computational Biology ; Datasets as Topic ; Gene Expression Profiling ; Healthy Volunteers ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/epidemiology ; Lung Neoplasms/immunology ; Protein Interaction Mapping ; Protein Interaction Maps/genetics ; Risk Factors ; Scleroderma, Systemic/epidemiology ; Scleroderma, Systemic/immunology
Czasopismo naukowe
Tytuł :
Network mapping of primary CD34+ cells by Ampliseq based whole transcriptome targeted resequencing identifies unexplored differentiation regulatory relationships.
Autorzy :
Schwaber JL; Avectas, Toronto, Ontario, Canada.
Korbie D; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Queensland, Australia.
Andersen S; Australian Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.
Lin E; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Queensland, Australia.
Chrysanthopoulos PK; BlueRock Therapeutics, Toronto, Ontario, Canada.
Trau M; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Queensland, Australia.
Nielsen LK; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Queensland, Australia.
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Źródło :
PloS one [PLoS One] 2021 Feb 05; Vol. 16 (2), pp. e0246107. Date of Electronic Publication: 2021 Feb 05 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Antigens, CD34/*metabolism
Fetal Blood/*cytology
Gene Expression Profiling/*methods
Neutrophils/*cytology
RNA, Untranslated/*genetics
Aryl Hydrocarbon Receptor Nuclear Translocator/genetics ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Cell Differentiation ; Cell Lineage ; Cell Proliferation ; DNA-Binding Proteins/genetics ; Female ; Fetal Blood/immunology ; Gene Expression Regulation ; Humans ; Mass Spectrometry ; Neutrophils/immunology ; Pregnancy ; Primary Cell Culture ; Proteomics ; Proto-Oncogene Proteins/genetics ; Sequence Analysis, RNA ; Trans-Activators/genetics ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Based on the whole genome clarified the evolution and expression process of fatty acid desaturase genes in three soybeans.
Autorzy :
Zhang B; Institute of Soil and Water Conservation, Chinese Academy of Sciences & Ministry of Water Resource, Yangling 712100, China; University of the Chinese Academy of Sciences, Beijing 100049, China.
Xia P; Zhejiang Province Key Laboratory of Plant Secondary Metabolism and Regulation, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China. Electronic address: .
Yu H; Institute of Soil and Water Conservation, Chinese Academy of Sciences & Ministry of Water Resource, Yangling 712100, China; University of the Chinese Academy of Sciences, Beijing 100049, China.
Li W; Institute of Soil and Water Conservation, Chinese Academy of Sciences & Ministry of Water Resource, Yangling 712100, China; University of the Chinese Academy of Sciences, Beijing 100049, China.
Chai W; Institute of Biotechnology, Hangzhou Academy of Agricultural Sciences, Hangzhou 310024, China.
Liang Z; Institute of Soil and Water Conservation, Chinese Academy of Sciences & Ministry of Water Resource, Yangling 712100, China; University of the Chinese Academy of Sciences, Beijing 100049, China; Zhejiang Province Key Laboratory of Plant Secondary Metabolism and Regulation, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 01; Vol. 182, pp. 1966-1980. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Gene Expression Regulation, Enzymologic*
Gene Expression Regulation, Plant*
Genome, Plant*
Fatty Acid Desaturases/*genetics
Soybeans/*enzymology
Soybeans/*genetics
Arabidopsis/genetics ; Chromosomes, Plant/genetics ; Conserved Sequence/genetics ; Droughts ; Fatty Acid Desaturases/metabolism ; Gene Duplication ; Gene Expression Profiling ; Genes, Plant ; Multigene Family ; Nucleotide Motifs/genetics ; Oryza/genetics ; Phylogeny ; Promoter Regions, Genetic ; Salt Stress/genetics ; Temperature
Czasopismo naukowe
Tytuł :
Comparative transcriptome analysis reveals distinct gene expression profiles in Brachypodium distachyon infected by two fungal pathogens.
Autorzy :
Zhu G; State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Gao C; State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Wu C; State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Li M; State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Xu JR; Department of Botany and Plant Pathology, Purdue University, West Lafayette, IN, 47907, USA.
Liu H; State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Wang Q; State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest A&F University, Yangling, 712100, Shaanxi, China. .
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Źródło :
BMC plant biology [BMC Plant Biol] 2021 Jun 30; Vol. 21 (1), pp. 304. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Gene Expression Regulation, Plant*
Ascomycota/*physiology
Brachypodium/*genetics
Brachypodium/*microbiology
Fusarium/*physiology
Gene Ontology ; Gene Regulatory Networks ; Host-Pathogen Interactions/genetics ; Plant Diseases/microbiology ; Protein Interaction Maps/genetics
SCR Organism :
Fusarium graminearum; Pyricularia oryzae
Czasopismo naukowe
Tytuł :
Integrated analysis of long noncoding RNAs and mRNA expression profiles reveals the potential role of lncRNAs in early stage of post-peripheral nerve injury in Sprague-Dawley rats.
Autorzy :
Zhang Y; Department of Plastic Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
Zhu Z; Department of Plastic Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
Liu X; Department of Plastic Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
Xu S; Department of Plastic Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
Zhang Y; Department of Plastic Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
Xu Y; Department of Plastic Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.
He B; Department of Orthopedics, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
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Źródło :
Aging [Aging (Albany NY)] 2021 May 08; Vol. 13 (10), pp. 13909-13925. Date of Electronic Publication: 2021 May 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Gene Expression Regulation*
Peripheral Nerve Injuries/*genetics
RNA, Long Noncoding/*genetics
RNA, Messenger/*genetics
Animals ; Gene Ontology ; Gene Regulatory Networks ; RNA, Long Noncoding/metabolism ; RNA, Messenger/metabolism ; Rats, Sprague-Dawley ; Reproducibility of Results ; Sciatic Nerve/metabolism ; Sciatic Nerve/pathology
Czasopismo naukowe
Tytuł :
Screen Key Genes Associated with Distraction-Induced Osteogenesis of Stem Cells Using Bioinformatics Methods.
Autorzy :
Chen J; UCL Centre for Biomaterials in Surgical Reconstruction and Regeneration, Division of Surgery & Interventional Science, University College London, London NW3 2PF, UK.
Hua J; UCL Institute of Orthopaedics and Musculoskeletal Science, Division of Surgery & Interventional Science, University College London, Stanmore, London HA7 4AP, UK.; The Griffin Institute (Northwick Park Institute for Medical Research), Harrow, London HA1 3UJ, UK.; Faculty of Science and Technology, Middlesex University, London NW4 4BT, UK.
Song W; UCL Centre for Biomaterials in Surgical Reconstruction and Regeneration, Division of Surgery & Interventional Science, University College London, London NW3 2PF, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 17; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*/methods
Transcriptome*
Computational Biology/*methods
Osteogenesis/*genetics
Stem Cells/*cytology
Stem Cells/*metabolism
Biomarkers ; Cell Differentiation/genetics ; Gene Ontology ; Gene Regulatory Networks ; Humans ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/metabolism ; Protein Interaction Mapping ; Protein Interaction Maps
Czasopismo naukowe
Tytuł :
In-Silico Evaluation of Genetic Alterations in Ovarian Carcinoma and Therapeutic Efficacy of NSC777201, as a Novel Multi-Target Agent for TTK, NEK2, and CDK1.
Autorzy :
Khedkar HN; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Academia Sinica, Taipei 11031, Taiwan.; Graduate Institute for Cancer Biology & Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.
Wang YC; Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Yadav VK; The Program for Translational Medicine, Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Shuang Ho Hospital, New Taipei City 23561, Taiwan.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Srivastava P; The Program for Translational Medicine, Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.
Lawal B; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Academia Sinica, Taipei 11031, Taiwan.; Graduate Institute for Cancer Biology & Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.
Mokgautsi N; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Academia Sinica, Taipei 11031, Taiwan.; Graduate Institute for Cancer Biology & Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.
Sumitra MR; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Academia Sinica, Taipei 11031, Taiwan.; Graduate Institute for Cancer Biology & Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.
Wu ATH; The Program for Translational Medicine, Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; The PhD Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan.; Clinical Research Center, Taipei Medical University Hospital, Taipei Medical University, Taipei 11031, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 11490, Taiwan.
Huang HS; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Academia Sinica, Taipei 11031, Taiwan.; Graduate Institute for Cancer Biology & Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 11490, Taiwan.; National Defense Medical Center, School of Pharmacy, Taipei 11490, Taiwan.; PhD Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 31; Vol. 22 (11). Date of Electronic Publication: 2021 May 31.
Typ publikacji :
Journal Article
MeSH Terms :
Computational Biology*/methods
Drug Discovery*/methods
Gene Expression Profiling*
Genetic Variation*
Ovarian Neoplasms/*genetics
Ovarian Neoplasms/*metabolism
Protein Kinase Inhibitors/*chemistry
Biomarkers, Tumor ; CDC2 Protein Kinase/antagonists & inhibitors ; CDC2 Protein Kinase/chemistry ; Cell Cycle Proteins/antagonists & inhibitors ; Cell Cycle Proteins/chemistry ; Female ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Humans ; Models, Molecular ; Molecular Conformation ; Molecular Structure ; NIMA-Related Kinases/antagonists & inhibitors ; NIMA-Related Kinases/chemistry ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/mortality ; Prognosis ; Protein Interaction Mapping ; Protein Interaction Maps ; Protein Kinase Inhibitors/pharmacology ; Protein-Serine-Threonine Kinases/antagonists & inhibitors ; Protein-Serine-Threonine Kinases/chemistry ; Protein-Tyrosine Kinases/antagonists & inhibitors ; Protein-Tyrosine Kinases/chemistry ; Structure-Activity Relationship ; Transcriptome
Czasopismo naukowe
Tytuł :
Potential role of chimeric genes in pathway-related gene co-expression modules.
Autorzy :
Li P; College of Life Science, Shihezi University, Shihezi, Xinjiang, 832000, China.
Li Y; College of Life Science, Shihezi University, Shihezi, Xinjiang, 832000, China.
Ma L; College of Life Science, Shihezi University, Shihezi, Xinjiang, 832000, China. .
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Źródło :
World journal of surgical oncology [World J Surg Oncol] 2021 May 12; Vol. 19 (1), pp. 149. Date of Electronic Publication: 2021 May 12.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Gene Regulatory Networks*
Animals ; Gene Ontology ; Prognosis ; Swine
Czasopismo naukowe
Tytuł :
Simultaneous learning of individual microRNA-gene interactions and regulatory comodules.
Autorzy :
Roth M; Google North America, San Francisco, USA.
Jain P; Electrical Engineering, Indian Institute of Technology Bombay, Mumbai, India.
Koo J; NVIDIA North America, Santa Clara, USA.
Chaterji S; Agricultural and Biological Engineering, Purdue University, West Lafayette, IN, USA. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 May 10; Vol. 22 (1), pp. 237. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
MicroRNAs*/genetics
Gene Expression Profiling ; Gene Expression Regulation ; Humans ; RNA, Messenger ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
Role of ethylene in the regulatory mechanism underlying the abortion of ovules after fertilization in Xanthoceras sorbifolium.
Autorzy :
Zhou Q; Institute of Botany, Chinese Academy of Sciences, Beijing, China. .; Key Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, Xiangshan, Beijing, China. .
Cai Q; Institute of Botany, Chinese Academy of Sciences, Beijing, China.
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Źródło :
Plant molecular biology [Plant Mol Biol] 2021 May; Vol. 106 (1-2), pp. 67-84. Date of Electronic Publication: 2021 Feb 21.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Plant*
Ethylenes/*metabolism
Fertilization/*genetics
Ovule/*physiology
Sapindaceae/*genetics
Sapindaceae/*physiology
DNA Fragmentation ; Fruit/drug effects ; Fruit/genetics ; Gene Expression Profiling ; Gene Ontology ; Gene Silencing ; Genes, Plant ; Models, Biological ; Molecular Sequence Annotation ; Ovule/genetics ; Phosphorus/deficiency ; Phosphorus/pharmacology ; Plant Growth Regulators/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Transcription Factors/metabolism ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
Variance in expression and localization of sex-related genes CgDsx, CgBHMG1 and CgFoxl2 during diploid and triploid Pacific oyster Crassostrea gigas gonad differentiation.
Autorzy :
Yue C; Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China.
Li Q; Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China; Laboratory of Tropical Marine Germplasm Resources and Breeding Engineering, Sanya Oceanographic Institution, Ocean University of China, Sanya 572000, China. Electronic address: .
Yu H; Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China.
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Źródło :
Gene [Gene] 2021 Jul 20; Vol. 790, pp. 145692. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Diploidy*
Gene Expression Regulation*
Sex Differentiation*
Triploidy*
DNA-Binding Proteins/*metabolism
Forkhead Box Protein L2/*metabolism
Gonads/*metabolism
Animals ; Crassostrea ; DNA-Binding Proteins/genetics ; Forkhead Box Protein L2/genetics ; Gene Expression Profiling ; Gene Regulatory Networks ; Gonads/growth & development
Czasopismo naukowe
Tytuł :
Mitochondrial ribosomal small subunit proteins (MRPS) MRPS6 and MRPS23 show dysregulation in breast cancer affecting tumorigenic cellular processes.
Autorzy :
Oviya RP; Department of Molecular Oncology, Cancer Institute (WIA), Adyar, Chennai 600020, Tamil Nadu, India.
Gopal G; Department of Molecular Oncology, Cancer Institute (WIA), Adyar, Chennai 600020, Tamil Nadu, India. Electronic address: .
Shirley SS; Department of Oncopathology, Cancer Institute (WIA), Adyar, Chennai 600020, Tamil Nadu, India.
Sridevi V; Department of Surgical Oncology, Cancer Institute (WIA), Adyar, Chennai 600020, Tamil Nadu, India.
Jayavelu S; Department of Molecular Oncology, Cancer Institute (WIA), Adyar, Chennai 600020, Tamil Nadu, India.
Rajkumar T; Department of Molecular Oncology, Cancer Institute (WIA), Adyar, Chennai 600020, Tamil Nadu, India.
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Źródło :
Gene [Gene] 2021 Jul 20; Vol. 790, pp. 145697. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenesis*
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
Breast Neoplasms/*pathology
Mitochondrial Proteins/*metabolism
Mitochondrial Ribosomes/*metabolism
Apoptosis ; Biomarkers, Tumor/genetics ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Cell Proliferation ; Female ; Gene Expression Profiling ; Gene Regulatory Networks ; Humans ; Mitochondrial Proteins/genetics ; Prognosis ; Tumor Cells, Cultured
Czasopismo naukowe

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