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Wyszukujesz frazę ""GENE expression profiling"" wg kryterium: Temat


Tytuł :
SARS-CoV-2 early infection signature identified potential key infection mechanisms and drug targets.
Autorzy :
Li Y; School of Pharmacy, Chapman University, Irvine, CA, 92618, USA.
Duche A; School of Pharmacy, Chapman University, Irvine, CA, 92618, USA.
Sayer MR; School of Pharmacy, Chapman University, Irvine, CA, 92618, USA.
Roosan D; College of Pharmacy, Western University of Health Sciences, Pomona, CA, 91766, USA.
Khalafalla FG; College of Pharmacy, California Health Sciences University, Clovis, CA, 93612, USA.
Ostrom RS; School of Pharmacy, Chapman University, Irvine, CA, 92618, USA.
Totonchy J; School of Pharmacy, Chapman University, Irvine, CA, 92618, USA.
Roosan MR; School of Pharmacy, Chapman University, Irvine, CA, 92618, USA. .
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Źródło :
BMC genomics [BMC Genomics] 2021 Feb 18; Vol. 22 (1), pp. 125. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Gene Expression Profiling*
COVID-19/*genetics
COVID-19/*virology
SARS-CoV-2/*physiology
A549 Cells ; COVID-19/diagnosis ; Gene Expression Regulation ; Humans ; Models, Biological ; Reproducibility of Results ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Molecular insight, expression profile and subcellular localization of two STAT family members, STAT1a and STAT2, from Japanese eel, Anguilla japonica.
Autorzy :
Liang Y; Fisheries College, Jimei University, Xiamen 361021, China; Fujian Engineering Research Center of Aquatic Breeding and Healthy Aquaculture, Xiamen 361021, China; Key Laboratory of Cultivation and High-value Utilization of Marine Organisms in Fujian Province, Xiamen 361000, China; Engineering Research Center of the Modern Technology for Eel Industry, Ministry of Education, P.R. China, Xiamen 361021, China. Electronic address: .
Liu H; Fisheries College, Jimei University, Xiamen 361021, China.
Li X; Fisheries College, Jimei University, Xiamen 361021, China.
Huang W; Fisheries College, Jimei University, Xiamen 361021, China; Engineering Research Center of the Modern Technology for Eel Industry, Ministry of Education, P.R. China, Xiamen 361021, China.
Huang B; Fisheries College, Jimei University, Xiamen 361021, China; Engineering Research Center of the Modern Technology for Eel Industry, Ministry of Education, P.R. China, Xiamen 361021, China.
Xu J; Fisheries College, Jimei University, Xiamen 361021, China; Engineering Research Center of the Modern Technology for Eel Industry, Ministry of Education, P.R. China, Xiamen 361021, China.
Xiong J; Fisheries College, Jimei University, Xiamen 361021, China; Engineering Research Center of the Modern Technology for Eel Industry, Ministry of Education, P.R. China, Xiamen 361021, China.
Zhai S; Fisheries College, Jimei University, Xiamen 361021, China; Engineering Research Center of the Modern Technology for Eel Industry, Ministry of Education, P.R. China, Xiamen 361021, China.
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Źródło :
Gene [Gene] 2021 Feb 15; Vol. 769, pp. 145257. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Anguilla/*metabolism
STAT Transcription Factors/*metabolism
Subcellular Fractions/*metabolism
Amino Acid Sequence ; Animals ; Base Sequence ; RNA, Messenger/genetics ; STAT Transcription Factors/chemistry ; STAT Transcription Factors/genetics ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
Transcriptome profiling analysis of tea plant (Camellia sinensis) using Oxford Nanopore long-read RNA-Seq technology.
Autorzy :
Wang F; The Department of Life Science and Agriculture, Qiannan Normal University for Nationalities, Duyun 558000, China. Electronic address: .
Chen Z; The Department of Life Science and Agriculture, Qiannan Normal University for Nationalities, Duyun 558000, China.
Pei H; The Department of Life Science and Agriculture, Qiannan Normal University for Nationalities, Duyun 558000, China.
Guo Z; The Department of Life Science and Agriculture, Qiannan Normal University for Nationalities, Duyun 558000, China.
Wen D; The Department of Life Science and Agriculture, Qiannan Normal University for Nationalities, Duyun 558000, China.
Liu R; The Department of Life Science and Agriculture, Qiannan Normal University for Nationalities, Duyun 558000, China.
Song B; The Department of Life Science and Agriculture, Qiannan Normal University for Nationalities, Duyun 558000, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Feb 15; Vol. 769, pp. 145247. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Camellia sinensis/*genetics
Sequence Analysis, RNA/*methods
Alternative Splicing
Czasopismo naukowe
Tytuł :
Identification of suitable mRNAs and microRNAs as reference genes for expression analyses in skin cells under sex hormone exposure.
Autorzy :
Fochi S; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Italy. Electronic address: .
Orlandi E; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Italy. Electronic address: .
Ceccuzzi L; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Italy. Electronic address: .
Rodolfo M; Melanoma and Sarcoma Surgery Unit and Unit of Immunotherapy, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: .
Vergani E; Melanoma and Sarcoma Surgery Unit and Unit of Immunotherapy, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: .
Turco A; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Italy. Electronic address: .
Romanelli MG; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Italy. Electronic address: .
Gomez-Lira M; Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biology and Genetics, University of Verona, Italy. Electronic address: .
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Źródło :
Gene [Gene] 2021 Feb 15; Vol. 769, pp. 145336. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Gonadal Steroid Hormones/*pharmacology
MicroRNAs/*genetics
RNA, Messenger/*genetics
Skin/*drug effects
Cell Line ; Humans ; Skin/metabolism
Czasopismo naukowe
Tytuł :
Identification, characterization, and expression profiles of insulin-like peptides suggest their critical roles in growth regulation of the Pacific oyster, Crassostrea gigas.
Autorzy :
Li Y; Key Laboratory of Mariculture (Ocean University of China), Ministry of Education, and College of Fisheries, Ocean University of China, Qingdao 266003, China.
Fu H; Key Laboratory of Mariculture (Ocean University of China), Ministry of Education, and College of Fisheries, Ocean University of China, Qingdao 266003, China.
Zhang F; Key Laboratory of Mariculture (Ocean University of China), Ministry of Education, and College of Fisheries, Ocean University of China, Qingdao 266003, China.
Ren L; Key Laboratory of Mariculture (Ocean University of China), Ministry of Education, and College of Fisheries, Ocean University of China, Qingdao 266003, China.
Tian J; Key Laboratory of Mariculture (Ocean University of China), Ministry of Education, and College of Fisheries, Ocean University of China, Qingdao 266003, China.
Li Q; Key Laboratory of Mariculture (Ocean University of China), Ministry of Education, and College of Fisheries, Ocean University of China, Qingdao 266003, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China.
Liu S; Key Laboratory of Mariculture (Ocean University of China), Ministry of Education, and College of Fisheries, Ocean University of China, Qingdao 266003, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Feb 15; Vol. 769, pp. 145244. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Crassostrea/*growth & development
Crassostrea/*metabolism
Insulin/*metabolism
Peptides/*metabolism
Amino Acid Sequence ; Animals ; Insulin/genetics ; Peptides/genetics ; Phylogeny
Czasopismo naukowe
Tytuł :
GEOlimma: differential expression analysis and feature selection using pre-existing microarray data.
Autorzy :
Lu L; Department of Biological Sciences, University of Memphis, Memphis, USA.; Department of Computer Science, University of Memphis, Memphis, USA.
Townsend KA; Department of Computer Science, University of Memphis, Memphis, USA.
Daigle BJ Jr; Department of Biological Sciences, University of Memphis, Memphis, USA. .; Department of Computer Science, University of Memphis, Memphis, USA. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Feb 03; Vol. 22 (1), pp. 44. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Computational Biology*
Gene Expression Profiling*
Bayes Theorem ; Child ; Female ; Humans ; Male ; Oligonucleotide Array Sequence Analysis ; Sample Size
Czasopismo naukowe
Tytuł :
Identification of Myocardial Infarction-Associated Genes Using Integrative microRNA-Gene Expression Network Analysis.
Autorzy :
Wang L; Department of Cardiology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yuan W; Department of Cardiology, Jiangsu Taizhou People's Hospital, Taizhou, China.
Huang J; Department of Cardiology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2021 Feb; Vol. 40 (2), pp. 348-358. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Gene Regulatory Networks*
MicroRNAs/*genetics
Myocardial Infarction/*genetics
Animals ; Cell Line ; Male ; Mice ; Myocardial Infarction/metabolism ; Protein Interaction Maps ; Rats
Czasopismo naukowe
Tytuł :
Time-course transcriptome analysis of lungs from mice exposed to ricin by intratracheal inoculation.
Autorzy :
Jiao Z; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Li S; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Su D; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Gan C; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Zhao X; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Gao B; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Qiu Y; Laboratory Animal Center, Academy of Military Medical Science, Beijing, 100071, China.
Song Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Zhou D; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Hu L; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China. Electronic address: .
Yang H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Feb 01; Vol. 337, pp. 57-67. Date of Electronic Publication: 2020 Nov 21.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Warfare Agents*
Gene Expression Profiling*
Lung Diseases/*chemically induced
Ricin/*administration & dosage
Ricin/*toxicity
Acute-Phase Reaction/chemically induced ; Acute-Phase Reaction/pathology ; Animals ; Bronchoalveolar Lavage Fluid ; Cytokines/metabolism ; Endoplasmic Reticulum Stress/drug effects ; Endoplasmic Reticulum Stress/genetics ; Female ; Gene Expression/drug effects ; Genome-Wide Association Study ; Inflammation/chemically induced ; Inflammation/pathology ; Intubation, Intratracheal ; Lung/pathology ; Lung Diseases/genetics ; Lung Diseases/pathology ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
MicroRNA and protein-coding gene expression analysis in idiopathic pulmonary fibrosis yields novel biomarker signatures associated to survival.
Autorzy :
Casanova NG; Department of Medicine, University of Arizona Health Sciences, Tucson, Arizona.
Zhou T; Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, Nevada.
Gonzalez-Garay ML; Department of Medicine, University of Arizona Health Sciences, Tucson, Arizona.
Lussier YA; Center for Biomedical Informatics and Biostatistics, University of Arizona, Tucson, Arizona.
Sweiss N; Section of Rheumatology Department of Medicine, University of Illinois at Chicago, Chicago, Illinois.
Ma SF; Section of Pulmonary/Critical Care, Department of Medicine, University of Chicago, Chicago, Illinois.
Noth I; Division of Pulmonary and Critical Care Department of Medicine, University of Virginia, Charlottesville, Virginia.
Knox KS; Department of Medicine, College of Medicine-Phoenix, University of Arizona Health Sciences, Phoenix, Arizona.
Garcia JGN; Department of Medicine, University of Arizona Health Sciences, Tucson, Arizona. Electronic address: .
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Źródło :
Translational research : the journal of laboratory and clinical medicine [Transl Res] 2021 Feb; Vol. 228, pp. 1-12. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Gene Expression Profiling*
Idiopathic Pulmonary Fibrosis/*genetics
MicroRNAs/*genetics
Proteins/*genetics
Aged ; Biomarkers/metabolism ; Case-Control Studies ; Female ; Humans ; Leukocytes, Mononuclear/metabolism ; Male ; Middle Aged ; Prognosis ; Reproducibility of Results ; Survival Analysis
Czasopismo naukowe
Tytuł :
Brain Transcriptome Analysis Reveals Potential Transcription Factors and Biological Pathways Associated with Feed Efficiency in Commercial DLY Pigs.
Autorzy :
Xu C; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Wang X; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Zhou S; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Wu J; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Geng Q; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Ruan D; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Qiu Y; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Quan J; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Ding R; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Cai G; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Wu Z; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Zheng E; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
Yang J; College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangdong, P.R. China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2021 Feb; Vol. 40 (2), pp. 272-282. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
Animal Feed*
Gene Expression Profiling*
Brain/*metabolism
Swine/*genetics
Swine/*metabolism
Transcription Factors/*metabolism
Animals ; Gene Ontology
Czasopismo naukowe
Tytuł :
Mining influential genes based on deep learning.
Autorzy :
Kong L; College of Agriculture, Nanjing Agricultural University, Jiangsu, 210095, Nanjing, China.
Chen Y; Department of Mathematics, College of Science, Nanjing Agricultural University, Nanjing, 210095, China.
Xu F; Department of Mathematics, College of Science, Nanjing Agricultural University, Nanjing, 210095, China.
Xu M; College of Agriculture, Nanjing Agricultural University, Jiangsu, 210095, Nanjing, China.
Li Z; College of Agriculture, Nanjing Agricultural University, Jiangsu, 210095, Nanjing, China.
Fang J; College of Agriculture, Nanjing Agricultural University, Jiangsu, 210095, Nanjing, China.
Zhang L; Department of Mathematics, College of Science, Nanjing Agricultural University, Nanjing, 210095, China. .
Pian C; Department of Mathematics, College of Science, Nanjing Agricultural University, Nanjing, 210095, China. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Jan 22; Vol. 22 (1), pp. 27. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
Deep Learning*
Gene Expression Profiling*
Genomics*
Genome ; Transcriptome
Czasopismo naukowe
Tytuł :
deepBase v3.0: expression atlas and interactive analysis of ncRNAs from thousands of deep-sequencing data.
Autorzy :
Xie F; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, The Fifth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Liu S; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, The Fifth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Wang J; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, The Fifth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Xuan J; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, The Fifth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Zhang X; School of Medicine, South China University of Technology, Guangzhou 510275, China.
Qu L; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, The Fifth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Zheng L; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, The Fifth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Yang J; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, The Fifth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.; Department of Interventional Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jan 08; Vol. 49 (D1), pp. D877-D883.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Databases, Nucleic Acid*
Gene Expression Profiling*
High-Throughput Nucleotide Sequencing*
RNA, Untranslated/*genetics
Animals ; Exosomes/metabolism ; Gene Expression Regulation ; Gene Regulatory Networks ; Genome ; Humans ; Molecular Sequence Annotation ; Prognosis ; RNA, Transfer/genetics ; RNA, Untranslated/metabolism ; User-Computer Interface
Czasopismo naukowe
Tytuł :
Transcriptomic analysis suggested the involvement of impaired lipid droplet biogenesis in graphene oxide-induced cytotoxicity in human umbilical vein endothelial cells.
Autorzy :
Luo Y; Key Laboratory of Environment-Friendly Chemistry and Application of Ministry of Education, Laboratory of Biochemistry, College of Chemistry, Xiangtan University, Xiangtan, 411105, China.
Wang X; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, 510632, China.
Cao Y; Key Laboratory of Environment-Friendly Chemistry and Application of Ministry of Education, Laboratory of Biochemistry, College of Chemistry, Xiangtan University, Xiangtan, 411105, China. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Jan 05; Vol. 333, pp. 109325. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
Cytotoxins/*toxicity
Graphite/*toxicity
Human Umbilical Vein Endothelial Cells/*drug effects
Human Umbilical Vein Endothelial Cells/*metabolism
Lipid Droplets/*drug effects
Lipid Droplets/*metabolism
Coenzyme A Ligases/genetics ; Fatty Acid Synthase, Type I/genetics ; Human Umbilical Vein Endothelial Cells/cytology ; Humans ; Oxidative Stress/drug effects ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus.
Autorzy :
Que L; Laboratory of Neural Connectivity, Brain Research Institute, Faculties of Medicine and Science, University of Zürich, Zürich, Switzerland.
Lukacsovich D; Laboratory of Neural Connectivity, Brain Research Institute, Faculties of Medicine and Science, University of Zürich, Zürich, Switzerland.
Luo W; Laboratory of Neural Connectivity, Brain Research Institute, Faculties of Medicine and Science, University of Zürich, Zürich, Switzerland.
Földy C; Laboratory of Neural Connectivity, Brain Research Institute, Faculties of Medicine and Science, University of Zürich, Zürich, Switzerland. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 04; Vol. 12 (1), pp. 108. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Hippocampus/*cytology
Interneurons/*cytology
Interneurons/*metabolism
Parvalbumins/*metabolism
Aging/genetics ; Animals ; Cell Adhesion Molecules/metabolism ; Cell Differentiation/genetics ; Electrophysiological Phenomena ; Female ; Gene Expression Regulation ; Hemoglobins/genetics ; Hemoglobins/metabolism ; Male ; Mice ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
Single-cell transcriptome profiling of the vaginal wall in women with severe anterior vaginal prolapse.
Autorzy :
Li Y; Medical Science Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, 100730, Beijing, China.
Zhang QY; CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences, 100101, Beijing, China.; Sino-Danish College, University of Chinese Academy of Sciences, 101408, Beijing, China.
Sun BF; CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences, 100101, Beijing, China.; China National Center for Bioinformation, 100101, Beijing, China.; University of Chinese Academy of Sciences, 100049, Beijing, China.; Institute of Stem Cell and Regeneration, Chinese Academy of Sciences, 100101, Beijing, China.
Ma Y; Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China.
Zhang Y; Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China.
Wang M; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China.
Ma C; Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China.
Shi H; Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China.
Sun Z; Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China.
Chen J; Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China.
Yang YG; CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences, 100101, Beijing, China. .; China National Center for Bioinformation, 100101, Beijing, China. .; University of Chinese Academy of Sciences, 100049, Beijing, China. .; Institute of Stem Cell and Regeneration, Chinese Academy of Sciences, 100101, Beijing, China. .
Zhu L; Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 04; Vol. 12 (1), pp. 87. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Severity of Illness Index*
Single-Cell Analysis*
Uterine Prolapse/*genetics
Vagina/*pathology
Aged ; Cell Communication/genetics ; Female ; Gene Expression Regulation ; Humans ; Ligands ; Middle Aged ; Pelvic Organ Prolapse/genetics ; Pelvic Organ Prolapse/pathology ; Receptors, Cell Surface/metabolism ; Transcription Factors/metabolism ; Uterine Prolapse/pathology
Czasopismo naukowe
Tytuł :
Global computational alignment of tumor and cell line transcriptional profiles.
Autorzy :
Warren A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Chen Y; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Jones A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Shibue T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Hahn WC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Boehm JS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Vazquez F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Tsherniak A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
McFarland JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 04; Vol. 12 (1), pp. 22. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Gene Expression Profiling*
Neoplasms/*genetics
Cell Line, Tumor ; Databases, Genetic ; Epithelial-Mesenchymal Transition/genetics ; Humans ; Integrins/metabolism
Czasopismo naukowe
Tytuł :
Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis.
Autorzy :
Sahlin K; Department of Mathematics, Science for Life Laboratory, Stockholm University, 106 91, Stockholm, Sweden.
Medvedev P; Department of Computer Science and Engineering, The Pennsylvania State University, University Park, PA, USA. .; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA. .; Center for Computational Biology and Bioinformatics, The Pennsylvania State University, University Park, PA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 04; Vol. 12 (1), pp. 2. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Profiling*
Nanopores*
Nanotechnology/*methods
Algorithms ; Alleles ; Animals ; Drosophila melanogaster/genetics ; Exons/genetics ; Gene Expression Regulation ; Heuristics ; Polymorphism, Single Nucleotide/genetics ; Protein Isoforms/metabolism ; RNA Splice Sites/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing.
Autorzy :
Arindrarto W; Center for Computational Biology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Borràs DM; GenomeScan B.V, 2333 BZ, Leiden, The Netherlands.; Department of Chemical Cell Biology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
de Groen RAL; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
van den Berg RR; Department of Human Genetics, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Locher IJ; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
van Diessen SAME; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
van der Holst R; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
van der Meijden ED; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Honders MW; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
de Leeuw RH; Forensic Laboratory for DNA Research, Department of Human Genetics, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Verlaat W; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Jedema I; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Kroes WGM; Department of Clinical Genetics, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Knijnenburg J; Department of Clinical Genetics, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
van Wezel T; Department of Pathology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Vermaat JSP; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Valk PJM; Department of Hematology, Erasmus University Medical Center, 3015CN, Rotterdam, The Netherlands.
Janssen B; GenomeScan B.V, 2333 BZ, Leiden, The Netherlands.
de Knijff P; Forensic Laboratory for DNA Research, Department of Human Genetics, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
van Bergen CAM; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
van den Akker EB; Center for Computational Biology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.; The Delft Bioinformatics Lab, Delft University of Technology, 2628CD, Delft, The Netherlands.; Section of Molecular Epidemiology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Hoen PAC'; Department of Human Genetics, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.; The Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.
Kiełbasa SM; Center for Computational Biology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Laros JFJ; Department of Human Genetics, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Griffioen M; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands. .
Veelken H; Department of Hematology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
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Źródło :
Leukemia [Leukemia] 2021 Jan; Vol. 35 (1), pp. 47-61. Date of Electronic Publication: 2020 Mar 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*/methods
Transcriptome*
Whole Exome Sequencing*/methods
Leukemia, Myeloid, Acute/*diagnosis
Leukemia, Myeloid, Acute/*genetics
Biomarkers, Tumor ; Computational Biology/methods ; Female ; Gene Expression Regulation, Leukemic ; Genetic Variation ; Genomics/methods ; Humans ; Male ; Molecular Diagnostic Techniques ; Mutation ; Oncogene Proteins, Fusion ; Prognosis ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
The coding capacity of SARS-CoV-2.
Autorzy :
Finkel Y; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Mizrahi O; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Nachshon A; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Weingarten-Gabbay S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismal and Evolutionary Biology, Harvard University, Cambridge, MA, USA.
Morgenstern D; de Botton Institute for Protein Profiling, The Nancy and Stephen Grand Israel National Center for Personalised Medicine, Weizmann Institute of Science, Rehovot, Israel.
Yahalom-Ronen Y; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Tamir H; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Achdout H; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Stein D; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona, Israel.
Israeli O; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona, Israel.
Beth-Din A; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona, Israel.
Melamed S; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Weiss S; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Israely T; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Paran N; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel.
Schwartz M; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Stern-Ginossar N; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. .
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Źródło :
Nature [Nature] 2021 Jan; Vol. 589 (7840), pp. 125-130. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Protein Biosynthesis*
Genome, Viral/*genetics
Open Reading Frames/*genetics
SARS-CoV-2/*genetics
Viral Proteins/*biosynthesis
Viral Proteins/*genetics
Animals ; Cell Line ; Humans ; Molecular Sequence Annotation ; Peptides/genetics ; Peptides/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Ribosomes/metabolism ; SARS-CoV-2/immunology ; SARS-CoV-2/metabolism ; SARS-CoV-2/pathogenicity ; Viral Proteins/metabolism
Czasopismo naukowe
Tytuł :
Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures.
Autorzy :
Furusawa H; Department of Medicine.
Cardwell JH; Department of Medicine.
Okamoto T; Department of Medicine.; Department of Radiology.
Walts AD; Department of Medicine.
Konigsberg IR; Department of Medicine.
Kurche JS; Department of Medicine.
Bang TJ; Department of Pathology, and.
Schwarz MI; Department of Medicine.
Brown KK; Department of Medicine.; Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Kropski JA; National Jewish Health, Denver, Colorado.
Rojas M; Vanderbilt University Medical Center, Nashville, Tennessee.
Cool CD; Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, Japan.; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
Lee JS; Department of Medicine.
Wolters PJ; Department of Internal Medicine, University of California, San Francisco, San Francisco, California.
Yang IV; Department of Medicine.
Schwartz DA; Department of Medicine.; Department of Immunology and Microbiology, University of Colorado, Aurora, Colorado.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2020 Nov 15; Vol. 202 (10), pp. 1430-1444.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Expression Profiling*
Alveolitis, Extrinsic Allergic/*genetics
Alveolitis, Extrinsic Allergic/*immunology
Idiopathic Pulmonary Fibrosis/*genetics
Idiopathic Pulmonary Fibrosis/*immunology
Lung Diseases, Interstitial/*genetics
Lung Diseases, Interstitial/*immunology
Adult ; Aged ; Aged, 80 and over ; Alveolitis, Extrinsic Allergic/physiopathology ; Female ; Gene Expression ; Humans ; Idiopathic Pulmonary Fibrosis/physiopathology ; Lung Diseases, Interstitial/physiopathology ; Male ; Middle Aged
Czasopismo naukowe

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