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Tytuł :
Quantification of SARS-CoV-2 neutralizing antibody by a pseudotyped virus-based assay.
Autorzy :
Nie J; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Li Q; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.; Graduate School of Peking Union Medical College, Beijing, China.
Wu J; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.; Wuhan Institute of Biological Products, Wuhan, China.
Zhao C; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Hao H; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Liu H; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Zhang L; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Nie L; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Qin H; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Wang M; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Lu Q; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Li X; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Sun Q; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Liu J; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China.
Fan C; Division of Animal Model Research, Institute for Laboratory Animal Resources, National Institutes for Food and Drug Control, Beijing, China.
Huang W; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China. .
Xu M; Institute for Biological Product Control, National Institutes for Food and Drug Control and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China. .
Wang Y; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and WHO Collaborating Center for Standardization and Evaluation of Biologicals, Beijing, China. .; Graduate School of Peking Union Medical College, Beijing, China. .
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Źródło :
Nature protocols [Nat Protoc] 2020 Nov; Vol. 15 (11), pp. 3699-3715. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Techniques*
Antibodies, Neutralizing/*analysis
Betacoronavirus/*immunology
Coronavirus Infections/*virology
Pneumonia, Viral/*virology
Animals ; COVID-19 ; Female ; HEK293 Cells ; Humans ; Mice ; Pandemics ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
The use of host cell DNA methylation analysis in the detection and management of women with advanced cervical intraepithelial neoplasia: a review.
Autorzy :
Kremer WW; Department of Pathology, Cancer Centre Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Steenbergen R; Department of Pathology, Cancer Centre Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Heideman D; Department of Pathology, Cancer Centre Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Kenter GG; Obstetrics and Gynaecology, Cancer Centre Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Centre for Gynaecological Oncology Amsterdam, Antoni van Leeuwenhoek-Netherlands Cancer Institute and Amsterdam UMC, Amsterdam, The Netherlands.
Meijer C; Department of Pathology, Cancer Centre Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
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Źródło :
BJOG : an international journal of obstetrics and gynaecology [BJOG] 2021 Feb; Vol. 128 (3), pp. 504-514. Date of Electronic Publication: 2020 Aug 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Genetic Techniques*
Cervical Intraepithelial Neoplasia/*diagnosis
DNA Methylation/*genetics
Early Detection of Cancer/*methods
Uterine Cervical Neoplasms/*diagnosis
Adult ; Carcinogenesis/genetics ; Cervical Intraepithelial Neoplasia/genetics ; Cervical Intraepithelial Neoplasia/virology ; Cervix Uteri/virology ; DNA, Viral/genetics ; Female ; Humans ; Middle Aged ; Papillomaviridae/genetics ; Papillomavirus Infections/complications ; Triage/methods ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/virology
Czasopismo naukowe
Tytuł :
[Three-dimensional chromosome conformation capture and its derived technologies].
Autorzy :
Tian H; Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, College of Life Sciences, Capital Normal University, Beijing 100048, China.
Yang Z; Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, College of Life Sciences, Capital Normal University, Beijing 100048, China.
Xu X; Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, College of Life Sciences, Capital Normal University, Beijing 100048, China.
Liu L; Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, College of Life Sciences, Capital Normal University, Beijing 100048, China.
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Źródło :
Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2020 Oct 25; Vol. 36 (10), pp. 2040-2050.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Chromatin*/genetics
Chromosomes*/chemistry
Chromosomes*/genetics
Genetic Techniques*
Cell Nucleus ; Genome/genetics
Czasopismo naukowe
Tytuł :
Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria.
Autorzy :
Lee RA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.; Division of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115.; Division of Infectious Diseases, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215.
Puig H; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.; Institute for Medical Engineering and Science, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
Nguyen PQ; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138.
Angenent-Mari NM; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.; Institute for Medical Engineering and Science, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
Donghia NM; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115.
McGee JP; Division of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115.
Dvorin JD; Division of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115.
Klapperich CM; Department of Biomedical Engineering, Boston University, Boston, MA 02215.
Pollock NR; Division of Infectious Diseases, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215.; Department of Laboratory Medicine, Boston Children's Hospital, Boston, MA 02115.
Collins JJ; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115; .; Institute for Medical Engineering and Science, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.; Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 13; Vol. 117 (41), pp. 25722-25731. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Clustered Regularly Interspaced Short Palindromic Repeats*
Diagnostic Techniques and Procedures*
Genetic Techniques*
Carrier State/*diagnosis
Malaria/*diagnosis
Plasmodium/*genetics
Plasmodium/*isolation & purification
Carrier State/parasitology ; Humans ; Malaria/parasitology ; Plasmodium/classification ; Plasmodium/physiology
Czasopismo naukowe
Tytuł :
Causal inference in genetic trio studies.
Autorzy :
Bates S; Department of Statistics, Stanford University, Stanford, CA 94305; .
Sesia M; Department of Data Sciences and Operations, Marshall School of Business, University of Southern California, Los Angeles, CA 90089.
Sabatti C; Department of Statistics, Stanford University, Stanford, CA 94305.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305.
Candès E; Department of Statistics, Stanford University, Stanford, CA 94305; .; Department of Mathematics, Stanford University, Stanford, CA 94305.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 29; Vol. 117 (39), pp. 24117-24126. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Comparative Study; Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Genetic Association Studies*
Genetic Techniques*
Genetic Variation*
Heredity*
Phenotype*
Humans
Czasopismo naukowe
Tytuł :
Comprehensive Dual- and Triple-Feature Intersectional Single-Vector Delivery of Diverse Functional Payloads to Cells of Behaving Mammals.
Autorzy :
Fenno LE; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Ramakrishnan C; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Kim YS; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Evans KE; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Lo M; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Vesuna S; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Inoue M; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Cheung KYM; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Yuen E; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Pichamoorthy N; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Hong ASO; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Deisseroth K; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Sep 09; Vol. 107 (5), pp. 836-853.e11. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Genetic Techniques*
Neurons*
Optogenetics*
Animals ; Dependovirus ; Genetic Vectors ; HEK293 Cells ; Humans
Czasopismo naukowe
Tytuł :
High-Resolution Whole-Genome Analysis of Sister-Chromatid Contacts.
Autorzy :
Espinosa E; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Université Paris Sud, 1 Avenue de la Terrasse, 91198 Gif-sur-Yvette, France.
Paly E; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Université Paris Sud, 1 Avenue de la Terrasse, 91198 Gif-sur-Yvette, France.
Barre FX; Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Université Paris Sud, 1 Avenue de la Terrasse, 91198 Gif-sur-Yvette, France. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Sep 03; Vol. 79 (5), pp. 857-869.e3. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Techniques*
Chromatids/*physiology
Vibrio cholerae/*genetics
Chromosomes, Bacterial/physiology ; DNA Replication ; DNA, Bacterial ; High-Throughput Nucleotide Sequencing ; Integrases/metabolism ; Nucleic Acid Conformation
Czasopismo naukowe
Tytuł :
Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non-Small Cell Lung Cancer.
Autorzy :
Li F; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Ng WL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Luster TA; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
Hu H; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Sviderskiy VO; Department of Pathology, New York University School of Medicine, New York, New York.
Dowling CM; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Hollinshead KER; Department of Radiation Oncology, Perlmutter Cancer Center, New York University School of Medicine, New York, New York.
Zouitine P; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Zhang H; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Huang Q; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Ranieri M; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Wang W; S. Arthur Localio Laboratory, Department of Surgery, New York University School of Medicine, New York, New York.
Fang Z; State Key Laboratory of Cell Biology, Innovation Center for Cell Signaling Network, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Chen T; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Deng J; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Zhao K; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.
So HC; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.; Department of Psychiatry, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.
Khodadadi-Jamayran A; Applied Bioinformatics Laboratories and Genome Technology Center, Division of Advanced Research Technologies, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Xu M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Karatza A; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Pyon V; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Li S; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Pan Y; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Labbe K; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Almonte C; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Poirier JT; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
Miller G; S. Arthur Localio Laboratory, Department of Surgery, New York University School of Medicine, New York, New York.
Possemato R; Department of Pathology, New York University School of Medicine, New York, New York.
Qi J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts. .; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Wong KK; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York. .
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Źródło :
Cancer research [Cancer Res] 2020 Sep 01; Vol. 80 (17), pp. 3556-3567. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Carcinoma, Non-Small-Cell Lung*/pathology
Genetic Techniques*
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Nuclear Proteins/*metabolism
Animals ; Cell Line, Tumor ; Clustered Regularly Interspaced Short Palindromic Repeats ; Epigenesis, Genetic ; Heterografts ; Humans ; Mice ; Nuclear Proteins/genetics
Czasopismo naukowe
Tytuł :
Comparison of commercial manual extraction kits for RNA isolation from canine whole blood.
Autorzy :
Tesfamichael DH; University of Wisconsin, Madison School of Veterinary Medicine, Madison, WI.
Wood MW; University of Wisconsin, Madison School of Veterinary Medicine, Madison, WI.
Pritchard JC; University of Wisconsin, Madison School of Veterinary Medicine, Madison, WI.
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Źródło :
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2020 Sep; Vol. 32 (5), pp. 737-741. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Blood Chemical Analysis/*veterinary
Dogs/*blood
Genetic Techniques/*veterinary
RNA/*isolation & purification
Animals ; Blood Chemical Analysis/instrumentation ; Genetic Techniques/instrumentation ; RNA/analysis ; Reagent Kits, Diagnostic/veterinary
Czasopismo naukowe
Tytuł :
SPARC enables genetic manipulation of precise proportions of cells.
Autorzy :
Isaacman-Beck J; Department of Neurobiology, Stanford University, Stanford, CA, USA.
Paik KC; Department of Neurobiology, Stanford University, Stanford, CA, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
Wienecke CFR; Department of Neurobiology, Stanford University, Stanford, CA, USA.
Yang HH; Department of Neurobiology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Fisher YE; Department of Neurobiology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Wang IE; Department of Neurobiology, Stanford University, Stanford, CA, USA.; Freenome, South San Francisco, CA, USA.
Ishida IG; Laboratory of Integrative Brain Function and Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Maimon G; Laboratory of Integrative Brain Function and Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Wilson RI; Department of Neurobiology and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Clandinin TR; Department of Neurobiology, Stanford University, Stanford, CA, USA. .
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Źródło :
Nature neuroscience [Nat Neurosci] 2020 Sep; Vol. 23 (9), pp. 1168-1175. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Genetic Techniques*
Neurons*
Recombinases*
Transgenes*
Animals ; Drosophila
Czasopismo naukowe
Tytuł :
A method for scoring the cell type-specific impacts of noncoding variants in personal genomes.
Autorzy :
Li W; Department of Statistics, Department of Biomedical Data Science, Bio-X Program, Stanford University, Stanford, CA 94305.; Ministry of Education Key Laboratory of Bioinformatics, Research Department of Bioinformatics at the Beijing National Research Center for Information Science and Technology, Center for Synthetic and Systems Biology, Department of Automation, Tsinghua University, Beijing 100084, China.
Duren Z; Department of Statistics, Department of Biomedical Data Science, Bio-X Program, Stanford University, Stanford, CA 94305.
Jiang R; Ministry of Education Key Laboratory of Bioinformatics, Research Department of Bioinformatics at the Beijing National Research Center for Information Science and Technology, Center for Synthetic and Systems Biology, Department of Automation, Tsinghua University, Beijing 100084, China .
Wong WH; Department of Statistics, Department of Biomedical Data Science, Bio-X Program, Stanford University, Stanford, CA 94305; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 01; Vol. 117 (35), pp. 21364-21372. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Genetic Techniques*
Genetic Variation*
Genome, Human*
Models, Genetic*
Regulatory Elements, Transcriptional*
Body Height/genetics ; Gene Expression Profiling ; Genome-Wide Association Study ; Humans ; Quantitative Trait Loci ; Software ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
[A temperature-inducible Targetron system for efficient gene inactivation in Escherichia coli].
Autorzy :
Zhao X; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang 550004, Guizhou, China.
Cheng Y; Department of ICU, The Affiliate Hospital of Guizhou Medical University, Guiyang 550004, Guizhou, China.
Wu C; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang 550004, Guizhou, China.
Ren W; Department of Immunology, Guizhou Medical University, Guiyang 550004, Guizhou, China.
Rao F; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang 550004, Guizhou, China.
Zhou Q; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang 550004, Guizhou, China.
Cui G; Department of Microbiology, Guizhou Medical University, Guiyang 550025, Guizhou, China.
Qi X; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang 550004, Guizhou, China.
Hong W; Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang 550004, Guizhou, China.
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Źródło :
Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2020 Aug 25; Vol. 36 (8), pp. 1659-1671.
Typ publikacji :
Journal Article
MeSH Terms :
Escherichia coli*/genetics
Gene Silencing*
Gene Targeting*/methods
Genetic Techniques*
Temperature*
Flagella ; Mutation ; Plasmids
Czasopismo naukowe
Tytuł :
A Pipeline using Bilateral In Utero Electroporation to Interrogate Genetic Influences on Rodent Behavior.
Autorzy :
Comer AL; The Graduate Program for Neuroscience, Boston University; Department of Biology, Boston University; Neurophotonics Center, Boston University; Center for Systems Neuroscience, Boston University.
Sriram B; Research and Early Development, Biogen.
Yen WW; Department of Biology, Boston University.
Cruz-Martín A; The Graduate Program for Neuroscience, Boston University; Department of Biology, Boston University; Neurophotonics Center, Boston University; Center for Systems Neuroscience, Boston University; Department Pharmacology and Experimental Therapeutics, Boston University; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 May 21 (159). Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Video-Audio Media
MeSH Terms :
Behavior, Animal*
Genetic Techniques*
Electroporation/*methods
Animals ; Feasibility Studies ; Mice ; Mice, Transgenic ; Plasmids/genetics
Czasopismo naukowe
Tytuł :
Development of a new macrophage-specific TRAP mouse (Mac ) and definition of the renal macrophage translational signature.
Autorzy :
Hofmeister A; Department of Internal Medicine and Nephrology, University Hospital Giessen and Marburg, Philipps-University, Marburg, Germany.
Thomaßen MC; Department of Internal Medicine and Nephrology, University Hospital Giessen and Marburg, Philipps-University, Marburg, Germany.
Markert S; Department of Internal Medicine and Nephrology, University Hospital Giessen and Marburg, Philipps-University, Marburg, Germany.
Marquardt A; Institute of Pathology, Julius-Maximilians-University Würzburg and Comprehensive Cancer Center Mainfranken, Würzburg, Germany.
Preußner M; Department of Internal Medicine and Nephrology, University Hospital Giessen and Marburg, Philipps-University, Marburg, Germany.
Rußwurm M; Department of Internal Medicine and Nephrology, University Hospital Giessen and Marburg, Philipps-University, Marburg, Germany.
Schermuly RT; Department of Internal Medicine, Universities of Giessen and Marburg Lung Center, Giessen, Germany.
Steinhoff U; Institute for Medical Microbiology and Hygiene, Philipps-University, Marburg, Germany.
Gröne HJ; Institute of Pharmacology, Philipps-University, Marburg, Germany.; Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany.
Hoyer J; Department of Internal Medicine and Nephrology, University Hospital Giessen and Marburg, Philipps-University, Marburg, Germany.
Humphreys BD; Division of Nephrology, Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.; Department of Developmental Biology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Grgic I; Department of Internal Medicine and Nephrology, University Hospital Giessen and Marburg, Philipps-University, Marburg, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2020 May 05; Vol. 10 (1), pp. 7519. Date of Electronic Publication: 2020 May 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Techniques*
Protein Biosynthesis*
Kidney/*cytology
Macrophages/*metabolism
Animals ; Dendritic Cells/metabolism ; Gene Expression Profiling ; Green Fluorescent Proteins/metabolism ; Immunohistochemistry ; Inflammation ; Mice ; Mice, Transgenic ; RNA/metabolism ; RNA-Seq ; Ribosomes/metabolism ; Transgenes
Czasopismo naukowe
Tytuł :
Adrenocortical tumorigenesis: Lessons from genetics.
Autorzy :
Kamilaris CDC; Section on Endocrinology and Genetics & Inter-Institute Endocrinology Fellowship Program, Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
Hannah-Shmouni F; Section on Endocrinology and Genetics & Inter-Institute Endocrinology Fellowship Program, Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
Stratakis CA; Section on Endocrinology and Genetics & Inter-Institute Endocrinology Fellowship Program, Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, 20892, USA. Electronic address: .
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Źródło :
Best practice & research. Clinical endocrinology & metabolism [Best Pract Res Clin Endocrinol Metab] 2020 May; Vol. 34 (3), pp. 101428. Date of Electronic Publication: 2020 May 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms :
Genetic Techniques*/trends
Adrenal Cortex/*pathology
Adrenal Cortex Neoplasms/*genetics
Carcinogenesis/*genetics
Adrenal Cortex/metabolism ; Adrenal Cortex Neoplasms/metabolism ; Adrenal Cortex Neoplasms/pathology ; Aldosterone/analysis ; Aldosterone/blood ; DNA Mutational Analysis ; Humans ; Hyperplasia/genetics ; Mutation ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
sRNA/L1 retrotransposition: using siRNAs and miRNAs to expand the applications of the cell culture-based LINE-1 retrotransposition assay.
Autorzy :
Tristan-Ramos P; Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, GENYO, Granada, Spain.; Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain.
Morell S; Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, GENYO, Granada, Spain.
Sanchez L; Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, GENYO, Granada, Spain.
Toledo B; Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, GENYO, Granada, Spain.; Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain.
Garcia-Perez JL; Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, GENYO, Granada, Spain.; MRC-Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Heras SR; Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, GENYO, Granada, Spain.; Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain.
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Źródło :
Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2020 Mar 30; Vol. 375 (1795), pp. 20190346. Date of Electronic Publication: 2020 Feb 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Techniques*
Long Interspersed Nucleotide Elements*
Retroelements*
MicroRNAs/*genetics
RNA, Small Interfering/*genetics
Cell Culture Techniques
Czasopismo naukowe
Tytuł :
Spectrochemical identification of kanamycin resistance genes in artificial microbial communities using Clover-assay.
Autorzy :
Jin N; School of Environment, Tsinghua University, Beijing 100084, PR China; Lancaster Environment Centre, Lancaster University, Lancaster LA1 4YQ, UK.
Morais CLM; Lancashire Teaching Hospitals NHS Trust, Fulwood, Preston PR2 9HT, UK.
Martin FL; Lancashire Teaching Hospitals NHS Trust, Fulwood, Preston PR2 9HT, UK; Biocel Ltd., Hull, Yorkshire, UK.
Zhang D; School of Environment, Tsinghua University, Beijing 100084, PR China; Lancaster Environment Centre, Lancaster University, Lancaster LA1 4YQ, UK; Research Institute for Environmental Innovation (Suzhou), Tsinghua, Suzhou 215163, PR China. Electronic address: .
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Źródło :
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2020 Mar 20; Vol. 181, pp. 113108. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Techniques*
Deuterium Oxide/*chemistry
Kanamycin Resistance/*genetics
Microbiota/*genetics
Spectrum Analysis, Raman/*methods
Czasopismo naukowe
Tytuł :
Targeting Key Genes to Tailor Old and New Crops for a Greener Agriculture.
Autorzy :
Fernie AR; Department of Molecular Physiology, Max-Planck-Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476 Potsdam, Germany. Electronic address: .
Yan J; National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China. Electronic address: .
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Źródło :
Molecular plant [Mol Plant] 2020 Mar 02; Vol. 13 (3), pp. 354-356. Date of Electronic Publication: 2020 Feb 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Agriculture*
Genetic Techniques*
Genes, Plant/*genetics
Cities ; Sustainable Development
Czasopismo naukowe
Tytuł :
Novel Genetically Encoded Bright Positive Calcium Indicator NCaMP7 Based on the mNeonGreen Fluorescent Protein.
Autorzy :
Subach OM; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.
Sotskov VP; Institute for Advanced Brain Studies, M.V. Lomonosov Moscow State University, Moscow 119991, Russia.
Plusnin VV; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.
Gruzdeva AM; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.; Institute for Advanced Brain Studies, M.V. Lomonosov Moscow State University, Moscow 119991, Russia.
Barykina NV; P.K. Anokhin Research Institute of Normal Physiology, Moscow 125315, Russia.
Ivashkina OI; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.; Institute for Advanced Brain Studies, M.V. Lomonosov Moscow State University, Moscow 119991, Russia.; P.K. Anokhin Research Institute of Normal Physiology, Moscow 125315, Russia.
Anokhin KV; Institute for Advanced Brain Studies, M.V. Lomonosov Moscow State University, Moscow 119991, Russia.; P.K. Anokhin Research Institute of Normal Physiology, Moscow 125315, Russia.
Nikolaeva AY; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.
Korzhenevskiy DA; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.
Vlaskina AV; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.
Lazarenko VA; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.
Boyko KM; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russia.
Rakitina TV; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow 117997, Russia.
Varizhuk AM; Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow 119435, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Moscow 119435, Russia.
Pozmogova GE; Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow 119435, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Moscow 119435, Russia.
Podgorny OV; M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow 117997, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow 117997, Russia.; N.K. Koltzov Institute of Developmental Biology, RAS, Moscow 119334, Russia.
Piatkevich KD; Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Westlake University, Hangzhou, Zhejiang 310024, China.
Boyden ES; Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Subach FV; National Research Center 'Kurchatov Institute', Moscow 123182, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Feb 28; Vol. 21 (5). Date of Electronic Publication: 2020 Feb 28.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Techniques*
Calcium/*metabolism
Green Fluorescent Proteins/*metabolism
Animals ; Behavior, Animal ; Cells, Cultured ; Crystallography, X-Ray ; Fluorometry ; HeLa Cells ; Hippocampus/metabolism ; Humans ; Indicators and Reagents ; Kinetics ; Mice, Inbred C57BL ; Models, Molecular ; Neurons/metabolism ; Photons ; Visual Cortex/physiology ; Wakefulness
Czasopismo naukowe

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