Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""GLUCOSE clamp technique"" wg kryterium: Temat


Tytuł :
NSAID-Induced Enteropathy Affects Regulation of Hepatic Glucose Production by Decreasing GLP-1 Secretion.
Autorzy :
Herz H; Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Song Y; Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Ye Y; Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Tian L; Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Linden B; Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Abu El Haija M; Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Stanford University School of Medicine & Lucile Packard Children's Hospital, Palo Alto, CA 94304, USA.
Chu Y; Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Grobe JL; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Comprehensive Rodent Metabolic Phenotyping Core, Medical College of Wisconsin, Milwaiukee, WI 53226, USA.; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Lengeling RW; Gastroenterology Section, Grand River Medical Group, Dubuque, IA 52001, USA.
Mokadem M; Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.; Fraternal Orders of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA 52242, USA.; Obesity Research & Education Initiative, University of Iowa, Iowa City, IA 52242, USA.; Veterans Affairs Health Care System, Iowa City, IA 52242, USA.
Pokaż więcej
Źródło :
Nutrients [Nutrients] 2021 Dec 28; Vol. 14 (1). Date of Electronic Publication: 2021 Dec 28.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*adverse effects
Glucagon-Like Peptide 1/*metabolism
Glucose/*biosynthesis
Intestinal Diseases/*chemically induced
Animals ; Diet, High-Fat ; Disease Models, Animal ; Glucagon-Like Peptide-1 Receptor/antagonists & inhibitors ; Glucose Clamp Technique ; Glucose Intolerance/chemically induced ; Ibuprofen/adverse effects ; Insulin/metabolism ; Insulin Resistance/physiology ; Liver/metabolism ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Pharmacokinetic and pharmacodynamic bioequivalence of biosimilar MYL-1601D with US and European insulin aspart in healthy volunteers: A randomized, double-blind, crossover, euglycaemic glucose clamp study.
Autorzy :
Hövelmann U; Profil Institute, Neuss, Germany.
Raiter Y; Viatris Inc., Amstelveen, The Netherlands.
Chullikana A; Biocon Biologics Limited, Bengaluru, India.
Liu M; Viatris Inc., Morgantown, West Virginia, USA.
Donnelly C; Viatris Inc., Morgantown, West Virginia, USA.
Lawrence T; Viatris Inc., Morgantown, West Virginia, USA.
Sengupta N; Biocon Biologics Limited, Bengaluru, India.
Cl G; Biocon Biologics Limited, Bengaluru, India.
Ranganna G; Viatris Inc., Bengaluru, India.
Barve A; Viatris Inc., Canonsburg, Pennsylvania, USA.
Pokaż więcej
Źródło :
Diabetes, obesity & metabolism [Diabetes Obes Metab] 2021 Dec; Vol. 23 (12), pp. 2670-2678. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Biosimilar Pharmaceuticals*/adverse effects
Insulin Aspart*
Area Under Curve ; Cross-Over Studies ; Double-Blind Method ; Glucose ; Glucose Clamp Technique ; Healthy Volunteers ; Humans ; Hypoglycemic Agents ; Therapeutic Equivalency
Czasopismo naukowe
Tytuł :
Mechanisms of action of duodenal mucosal resurfacing in insulin resistant women with polycystic ovary syndrome.
Autorzy :
Kaur V; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK.
Dimitriadis GK; Department of Endocrinology, King's College Hospital NHS Foundation Trust, Denmark Hill, SE5 9RS, UK.
Pérez-Pevida B; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK.
Bansi DS; Department of Gastroenterology, Imperial College Healthcare NHS Trust, UK.
Jayasena C; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK.
Bate D; Warwickshire Institute for Diabetes, Endocrinology & Metabolism, University Hospitals Coventry & Warwickshire, UK.
Houghton R; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK.
Fielding BA; Department of Nutritional Sciences, University of Surrey, UK.
Balfoussia D; Department of Gynaecology, Imperial College Healthcare NHS Trust, UK.
Webber L; Department of Gynaecology, Imperial College Healthcare NHS Trust, UK.
Miao Y; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK.
Mears F; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK.
Jackson N; Department of Nutritional Sciences, University of Surrey, UK.
Coppin L; Department of Nutritional Sciences, University of Surrey, UK.
Perez J; Biostatistics, Avania Clinical, USA.
Williams M; Biostatistics, Avania Clinical, USA.
Johnson B; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK.
Umpleby AM; Department of Nutritional Sciences, University of Surrey, UK.
Randeva HS; Warwickshire Institute for Diabetes, Endocrinology & Metabolism, University Hospitals Coventry & Warwickshire, UK; Department of Experimental & Translational Medicine, Warwick Medical School, UK.
Miras AD; Department of Metabolism, Digestion and Reproduction, Imperial College London, UK. Electronic address: .
Pokaż więcej
Źródło :
Metabolism: clinical and experimental [Metabolism] 2021 Dec; Vol. 125, pp. 154908. Date of Electronic Publication: 2021 Oct 07.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Duodenum/*metabolism
Endoscopy/*methods
Glycated Hemoglobin A/*analysis
Insulin Resistance/*physiology
Intestinal Mucosa/*metabolism
Obesity/*metabolism
Polycystic Ovary Syndrome/*therapy
Adult ; Double-Blind Method ; Female ; Glucose Clamp Technique ; Glucose Tolerance Test ; Humans ; Polycystic Ovary Syndrome/metabolism ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Novel Laboratory Index, Based on Fasting Blood Parameters, Accurately Reflects Insulin Sensitivity.
Autorzy :
Karczewska-Kupczewska M; Department of Internal Medicine and Metabolic Diseases, Medical University of Białystok, 15-276 Białystok, Poland.
Nikołajuk A; Department of Prophylaxis of Metabolic Diseases, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.
Stefanowicz M; Department of Metabolic Diseases, Medical University of Białystok, Białystok, Poland.
Matulewicz N; Department of Metabolic Diseases, Medical University of Białystok, Białystok, Poland.
Arnoriaga-Rodriguez M; Department of Diabetes, Endocrinology and Nutrition, Dr. Josep Trueta University Hospital; Department of Medical Sciences, Faculty of Medicine, University of Girona; and CIBERobn Pathophysiology of Obesity and Nutrition, Girona, Spain.
Fernandez-Real JM; Department of Diabetes, Endocrinology and Nutrition, Dr. Josep Trueta University Hospital; Department of Medical Sciences, Faculty of Medicine, University of Girona; and CIBERobn Pathophysiology of Obesity and Nutrition, Girona, Spain.
Strączkowski M; Department of Prophylaxis of Metabolic Diseases, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.
Pokaż więcej
Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2021 Nov 19; Vol. 106 (12), pp. e5208-e5221.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fasting*
Insulin Resistance*
Blood Glucose/*analysis
Diabetes Mellitus, Type 2/*diagnosis
Laboratories/*statistics & numerical data
Obesity/*physiopathology
Prediabetic State/*diagnosis
Adolescent ; Adult ; Biomarkers/blood ; Cohort Studies ; Diabetes Mellitus, Type 2/blood ; Female ; Follow-Up Studies ; Glucose Clamp Technique ; Glucose Tolerance Test ; Humans ; Insulin/blood ; Male ; Prediabetic State/blood ; Prognosis ; Young Adult
Czasopismo naukowe
Tytuł :
Serum secreted frizzled-related protein 5 in relation to insulin sensitivity and its regulation by insulin and free fatty acids.
Autorzy :
Rydzewska M; Department of Internal Medicine and Metabolic Diseases, Medical University of Białystok, Białystok, Poland.
Nikołajuk A; Department of Prophylaxis of Metabolic Diseases, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.
Matulewicz N; Department of Metabolic Diseases, Medical University of Białystok, Białystok, Poland.
Stefanowicz M; Department of Metabolic Diseases, Medical University of Białystok, Białystok, Poland.
Karczewska-Kupczewska M; Department of Internal Medicine and Metabolic Diseases, Medical University of Białystok, Białystok, Poland. .
Pokaż więcej
Źródło :
Endocrine [Endocrine] 2021 Nov; Vol. 74 (2), pp. 300-307. Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptor Proteins, Signal Transducing*
Fatty Acids, Nonesterified*
Insulin Resistance*
Glucose Clamp Technique ; Humans ; Insulin ; Intracellular Signaling Peptides and Proteins ; Male
Czasopismo naukowe
Tytuł :
Good agreement between hyperinsulinemic-euglycemic clamp and 2 hours oral minimal model assessed insulin sensitivity in adolescents.
Autorzy :
Carreau AM; Department of Pediatrics, Division of Pediatric Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Xie D; Department of Pediatrics, Division of Pediatric Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Garcia-Reyes Y; Department of Pediatrics, Division of Pediatric Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Rahat H; Department of Pediatrics, Division of Pediatric Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Bartlette K; Department of Applied Mathematics and Statistics, Colorado School of Mines, Golden, Colorado, USA.
Behn CD; Department of Pediatrics, Division of Pediatric Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.; Department of Applied Mathematics and Statistics, Colorado School of Mines, Golden, Colorado, USA.
Pyle L; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.; Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado, USA.
Nadeau KJ; Department of Pediatrics, Division of Pediatric Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.; Center for Women's Health Research, Aurora, Colorado, USA.
Cree-Green M; Department of Pediatrics, Division of Pediatric Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.; Center for Women's Health Research, Aurora, Colorado, USA.
Pokaż więcej
Źródło :
Pediatric diabetes [Pediatr Diabetes] 2020 Nov; Vol. 21 (7), pp. 1159-1168. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucose Clamp Technique*
Insulin Resistance*
Polycystic Ovary Syndrome/*metabolism
Adolescent ; Age Factors ; Body Mass Index ; Child ; Cross-Sectional Studies ; Female ; Glucose Tolerance Test ; Humans ; Polycystic Ovary Syndrome/complications ; Reproducibility of Results ; Young Adult
Czasopismo naukowe
Tytuł :
Real-time Continuous Glucose Monitoring During a Hyperinsulinemic-Hypoglycemic Clamp Significantly Underestimates the Degree of Hypoglycemia.
Autorzy :
Farrell CM; Division of Systems Medicine, School of Medicine, University of Dundee, Dundee, U.K.
McNeilly AD; Division of Systems Medicine, School of Medicine, University of Dundee, Dundee, U.K.
Hapca SM; Computing Science and Mathematics, Faculty of Natural Sciences, University of Stirling, Stirling, U.K.
McCrimmon RJ; Division of Systems Medicine, School of Medicine, University of Dundee, Dundee, U.K. .
Pokaż więcej
Źródło :
Diabetes care [Diabetes Care] 2020 Oct; Vol. 43 (10), pp. e142-e143. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Controlled Clinical Trial; Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucose Clamp Technique*/instrumentation
Glucose Clamp Technique*/methods
Blood Glucose/*analysis
Diabetes Mellitus, Type 1/*blood
Hypoglycemia/*blood
Hypoglycemia/*diagnosis
Adult ; Awareness ; Blood Glucose/metabolism ; Blood Glucose Self-Monitoring/instrumentation ; Blood Glucose Self-Monitoring/methods ; Computer Systems ; Diabetes Mellitus, Type 1/diagnosis ; Diabetes Mellitus, Type 1/drug therapy ; Female ; Humans ; Hypoglycemia/chemically induced ; Hypoglycemia/psychology ; Hypoglycemic Agents/administration & dosage ; Insulin/administration & dosage ; Male ; Predictive Value of Tests
Raport
Tytuł :
Lipid accumulation product (LAP) as a potential index to predict risk of insulin resistance in young, non-obese Asian Indian males from Southern India: observations from hyperinsulinemic-euglycemic clamp studies.
Autorzy :
Anoop S S; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.
Dasgupta R; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India .
Rebekah G; Biostatistics, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.
Jose A; Department of Clinical Biochemistry, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.
Inbakumari MP; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.
Finney G; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.
Thomas N; Department of Clinical Biochemistry, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.
Pokaż więcej
Źródło :
BMJ open diabetes research & care [BMJ Open Diabetes Res Care] 2021 Sep; Vol. 9 (1).
Typ publikacji :
Journal Article
MeSH Terms :
Insulin Resistance*
Lipid Accumulation Product*
Glucose Clamp Technique ; Humans ; India/epidemiology ; Male ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Subcutaneous Adipose Tissue Metabolic Function and Insulin Sensitivity in People With Obesity.
Autorzy :
Koh HE; Division of Geriatrics and Nutritional Science, Washington University School of Medicine, St. Louis, MO.
van Vliet S; Division of Geriatrics and Nutritional Science, Washington University School of Medicine, St. Louis, MO.
Pietka TA; Division of Geriatrics and Nutritional Science, Washington University School of Medicine, St. Louis, MO.
Meyer GA; Program in Physical Therapy, Washington University School of Medicine, St. Louis, MO.
Razani B; Division of Cardiology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
Laforest R; Department of Radiology, Washington University School of Medicine, St. Louis, MO.
Gropler RJ; Department of Radiology, Washington University School of Medicine, St. Louis, MO.
Mittendorfer B; Division of Geriatrics and Nutritional Science, Washington University School of Medicine, St. Louis, MO .
Pokaż więcej
Źródło :
Diabetes [Diabetes] 2021 Oct; Vol. 70 (10), pp. 2225-2236. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance/*physiology
Obesity/*metabolism
Subcutaneous Fat/*metabolism
Adult ; Body Composition/physiology ; Case-Control Studies ; Female ; Glucose/metabolism ; Glucose Clamp Technique ; Humans ; Insulin/pharmacology ; Lipolysis/drug effects ; Male ; Middle Aged ; Obesity/pathology ; Subcutaneous Fat/drug effects ; Subcutaneous Fat/pathology
Czasopismo naukowe
Tytuł :
Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons.
Autorzy :
Farias Quipildor G; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY.; Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY.; Fleischer Institute for Diabetes & Metabolism, Albert Einstein College of Medicine, Bronx, NY.
Mao K; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY.; Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY.; Fleischer Institute for Diabetes & Metabolism, Albert Einstein College of Medicine, Bronx, NY.
Beltran PJ; Oncology Research, Amgen Inc., Thousand Oaks, CA.
Barzilai N; Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY.; Fleischer Institute for Diabetes & Metabolism, Albert Einstein College of Medicine, Bronx, NY.; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY.; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY.
Huffman DM; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY .; Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY.; Fleischer Institute for Diabetes & Metabolism, Albert Einstein College of Medicine, Bronx, NY.; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY.
Pokaż więcej
Źródło :
Diabetes [Diabetes] 2021 Oct; Vol. 70 (10), pp. 2237-2249. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Glucose/*metabolism
Insulin/*pharmacology
Neurons/*physiology
Adult ; Agouti-Related Protein/genetics ; Agouti-Related Protein/metabolism ; Animals ; Carbohydrate Metabolism/drug effects ; Carbohydrate Metabolism/genetics ; Cells, Cultured ; Glucose Clamp Technique ; Humans ; Hypothalamus/drug effects ; Hypothalamus/metabolism ; Injections, Intraventricular ; Insulin/administration & dosage ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neurons/drug effects ; Neurons/metabolism ; Rats ; Rats, Inbred BN ; Rats, Inbred F344 ; Receptor, IGF Type 1/genetics ; Receptor, IGF Type 1/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Hyperinsulinemic Compensation for Insulin Resistance Occurs Independent of Elevated Glycemia in Male Dogs.
Autorzy :
Ader M; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Pokaż więcej
Źródło :
Endocrinology [Endocrinology] 2021 Sep 01; Vol. 162 (9).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hyperglycemia/*complications
Hyperinsulinism/*etiology
Insulin Resistance/*physiology
Animals ; Blood Glucose/physiology ; Diet, High-Fat/adverse effects ; Dogs ; Glucose Clamp Technique ; Glucose Tolerance Test ; Hyperglycemia/metabolism ; Hyperinsulinism/metabolism ; Male
Czasopismo naukowe
Tytuł :
FXR in the dorsal vagal complex is sufficient and necessary for upper small intestinal microbiome-mediated changes of TCDCA to alter insulin action in rats.
Autorzy :
Zhang SY; Toronto General Hospital Research Institute, UHN, Toronto, Ontario, Canada.
Li RJW; Toronto General Hospital Research Institute, UHN, Toronto, Ontario, Canada.; Physiology, University of Toronto, Toronto, Ontario, Canada.
Lim YM; Toronto General Hospital Research Institute, UHN, Toronto, Ontario, Canada.; Medical Research Institute, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Batchuluun B; Toronto General Hospital Research Institute, UHN, Toronto, Ontario, Canada.
Liu H; Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, Beijing, China.
Waise TMZ; Toronto General Hospital Research Institute, UHN, Toronto, Ontario, Canada.
Lam TKT; Toronto General Hospital Research Institute, UHN, Toronto, Ontario, Canada .; Physiology, University of Toronto, Toronto, Ontario, Canada.; Medicine, University of Toronto, Toronto, Ontario, Canada.; Banting and Best Diabetes Centre, University of Toronto, Toronto, Ontario, Canada.
Pokaż więcej
Źródło :
Gut [Gut] 2021 Sep; Vol. 70 (9), pp. 1675-1683. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance*/physiology
Brain Stem/*physiology
Gastrointestinal Microbiome/*physiology
Intestine, Small/*microbiology
Receptors, Cytoplasmic and Nuclear/*metabolism
Taurochenodeoxycholic Acid/*metabolism
Animals ; Brain/metabolism ; Brain Chemistry ; Brain Stem/metabolism ; Diet, High-Fat ; Fecal Microbiota Transplantation ; Gene Knockdown Techniques ; Glucose Clamp Technique ; Intestine, Small/metabolism ; Rats ; Receptors, Cytoplasmic and Nuclear/analysis ; Taurochenodeoxycholic Acid/analysis
Czasopismo naukowe
Tytuł :
A single bout of exercise improves vascular insulin sensitivity in adults with obesity.
Autorzy :
Heiston EM; Department of Internal Medicine, Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA.; Department of Kinesiology, University of Virginia, Charlottesville, Virginia, USA.
Liu Z; Division of Endocrinology & Metabolism, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Ballantyne A; Department of Kinesiology, University of Virginia, Charlottesville, Virginia, USA.
Kranz S; Department of Kinesiology, University of Virginia, Charlottesville, Virginia, USA.
Malin SK; Department of Kinesiology, University of Virginia, Charlottesville, Virginia, USA.; Department of Kinesiology & Health, Rutgers University, New Brunswick, New Jersey, USA.; Division of Endocrinology, Metabolism & Nutrition, Department of Medicine, Rutgers University, New Brunswick, New Jersey, USA.; The New Jersey Institute for Food, Nutrition and Health, Rutgers University, New Brunswick, New Jersey, USA.; Institute of Translational Medicine and Science, Rutgers University, New Brunswick, New Jersey, USA.
Pokaż więcej
Źródło :
Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2021 Sep; Vol. 29 (9), pp. 1487-1496. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji :
Controlled Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance*
Adult ; Blood Glucose ; Cross-Over Studies ; Glucose Clamp Technique ; Humans ; Insulin ; Obesity
Czasopismo naukowe
Tytuł :
New Insights on the Interactions Between Insulin Clearance and the Main Glucose Homeostasis Mechanisms.
Autorzy :
Bizzotto R; CNR Institute of Neuroscience, Padua, Italy .
Tricò D; Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
Natali A; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Gastaldelli A; CNR Institute of Clinical Physiology, Padua, Italy.
Muscelli E; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
De Fronzo RA; Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX.
Arslanian S; Center for Pediatric Research in Obesity and Metabolism, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA.
Ferrannini E; CNR Institute of Clinical Physiology, Padua, Italy.
Mari A; CNR Institute of Neuroscience, Padua, Italy.
Pokaż więcej
Źródło :
Diabetes care [Diabetes Care] 2021 Sep; Vol. 44 (9), pp. 2115-2123. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2*
Insulin Resistance*
Blood Glucose ; Female ; Glucose ; Glucose Clamp Technique ; Homeostasis ; Humans ; Insulin/metabolism ; Insulin Secretion
Czasopismo naukowe
Tytuł :
Insulin-Mediated Substrate Use in Women With Different Phenotypes of PCOS: the Role of Androgens.
Autorzy :
Tosi F; Endocrinology, Diabetes and Metabolism, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona I-37126, Italy.
Villani M; Endocrinology, Diabetes and Metabolism, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona I-37126, Italy.
Migazzi M; Endocrinology, Diabetes and Metabolism, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona I-37126, Italy.
Faccin G; Endocrinology, Diabetes and Metabolism, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona I-37126, Italy.
Garofalo S; Endocrinology, Diabetes and Metabolism, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona I-37126, Italy.
Fiers T; Laboratory for Hormonology and Department of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium.
Kaufman JM; Laboratory for Hormonology and Department of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium.
Bonora E; Endocrinology, Diabetes and Metabolism, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona I-37126, Italy.
Moghetti P; Endocrinology, Diabetes and Metabolism, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona I-37126, Italy.
Pokaż więcej
Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2021 Aug 18; Vol. 106 (9), pp. e3414-e3425.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Androgens/*metabolism
Insulin/*metabolism
Polycystic Ovary Syndrome/*metabolism
Adiposity ; Adult ; Androgens/blood ; Blood Glucose/metabolism ; Calorimetry, Indirect ; Fatty Acids, Nonesterified/blood ; Female ; Glucose/metabolism ; Glucose Clamp Technique ; Humans ; Hyperinsulinism/blood ; Hyperinsulinism/metabolism ; Lipid Metabolism ; Ovulation ; Oxidation-Reduction ; Phenotype ; Young Adult
Czasopismo naukowe
Tytuł :
Additional Insulin Is Required in Both the Early and Late Postprandial Periods for Meals High in Protein and Fat: A Randomized Trial.
Autorzy :
Keating B; Perth Children's Hospital, Nedlands, WA, 6009, Australia.; Telethon Kids Institute, The University of Western Australia, Nedlands, WA, 6009, Australia.
Smart CEM; John Hunter Children's Hospital, New Lambton Heights, NSW, 2305, Australia.; Hunter Medical Research Institute, New Lambton Heights, NSW, 2305, Australia.; University of Newcastle, Callaghan, NSW, 2308, Australia.
Harray AJ; Telethon Kids Institute, The University of Western Australia, Nedlands, WA, 6009, Australia.; Curtin University, Bentley, WA, 6102, Australia.
Paramalingam N; Perth Children's Hospital, Nedlands, WA, 6009, Australia.; Telethon Kids Institute, The University of Western Australia, Nedlands, WA, 6009, Australia.; The University of Western Australia, Crawley, WA, 6009, Australia.
Smith G; Perth Children's Hospital, Nedlands, WA, 6009, Australia.
Jones TW; Perth Children's Hospital, Nedlands, WA, 6009, Australia.; Telethon Kids Institute, The University of Western Australia, Nedlands, WA, 6009, Australia.; The University of Western Australia, Crawley, WA, 6009, Australia.
King BR; John Hunter Children's Hospital, New Lambton Heights, NSW, 2305, Australia.; Hunter Medical Research Institute, New Lambton Heights, NSW, 2305, Australia.; University of Newcastle, Callaghan, NSW, 2308, Australia.
Davis EA; Perth Children's Hospital, Nedlands, WA, 6009, Australia.; Telethon Kids Institute, The University of Western Australia, Nedlands, WA, 6009, Australia.; The University of Western Australia, Crawley, WA, 6009, Australia.
Pokaż więcej
Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2021 Aug 18; Vol. 106 (9), pp. e3611-e3618.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Postprandial Period*
Diabetes Mellitus, Type 1/*blood
Diabetes Mellitus, Type 1/*drug therapy
Dietary Fats/*pharmacology
Dietary Proteins/*pharmacology
Hypoglycemic Agents/*therapeutic use
Insulin/*therapeutic use
Adolescent ; Blood Glucose/analysis ; Child ; Cross-Over Studies ; Dietary Carbohydrates ; Female ; Glucose Clamp Technique ; Humans ; Hypoglycemic Agents/administration & dosage ; Insulin/administration & dosage ; Male ; Meals ; Young Adult
Czasopismo naukowe
Tytuł :
ALDH2 rs671 Is Associated With Elevated FPG, Reduced Glucose Clearance and Hepatic Insulin Resistance in Japanese Men.
Autorzy :
Takeno K; Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.; Sportology Center, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
Tamura Y; Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.; Sportology Center, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
Kakehi S; Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.; Sportology Center, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
Kaga H; Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
Kawamori R; Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.; Sportology Center, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
Watada H; Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.; Sportology Center, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.; Center for Identification of Diabetic Therapeutic Targets, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.; Center for Molecular Diabetology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
Pokaż więcej
Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2021 Aug 18; Vol. 106 (9), pp. e3573-e3581.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Aldehyde Dehydrogenase, Mitochondrial/*genetics
Blood Glucose/*metabolism
Insulin Resistance/*genetics
Liver/*metabolism
Adiposity/genetics ; Adult ; Alcohol Drinking/genetics ; Asians ; Genome-Wide Association Study ; Genotype ; Glucose Clamp Technique ; Humans ; Lipid Metabolism/genetics ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Male ; Middle Aged ; Muscle, Skeletal/metabolism ; Prospective Studies
Czasopismo naukowe
Tytuł :
Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans.
Autorzy :
Axelrod CL; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA; Department of Translational Services, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Fealy CE; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Erickson ML; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Davuluri G; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA; Sarcopenia and Malnutrition Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Fujioka H; Cryo-Electron Microscopy Core, Case Western Reserve University, Cleveland, OH 44109, USA; Center for Mitochondrial Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Dantas WS; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Huang E; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Pergola K; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA; Department of Translational Services, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Mey JT; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
King WT; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA; Department of Translational Services, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Mulya A; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Hsia D; Clinical Trials Unit, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Burguera B; Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
Tandler B; Center for Mitochondrial Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Department of Biological Sciences, Case Western Reserve University School of Dental Medicine, Cleveland, OH 44106, USA.
Hoppel CL; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA; Center for Mitochondrial Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Department of Pharmacology, Case Western Reserve University, Cleveland, OH 44109, USA.
Kirwan JP; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. Electronic address: .
Pokaż więcej
Źródło :
Metabolism: clinical and experimental [Metabolism] 2021 Aug; Vol. 121, pp. 154803. Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms :
Insulin/*metabolism
Lipids/*pharmacology
Mitochondria, Muscle/*drug effects
Mitochondrial Dynamics/*drug effects
Adult ; Biopsy ; Cell Respiration/drug effects ; Emulsions/administration & dosage ; Emulsions/pharmacology ; Fatty Acids/administration & dosage ; Fatty Acids/pharmacology ; Female ; Glucose Clamp Technique ; Healthy Volunteers ; Humans ; Infusions, Intravenous ; Insulin Resistance/physiology ; Lipid Metabolism/drug effects ; Lipid Metabolism/physiology ; Lipids/administration & dosage ; Male ; Metabolic Networks and Pathways/drug effects ; Mitochondria, Muscle/pathology ; Mitochondria, Muscle/physiology ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Phospholipids/administration & dosage ; Phospholipids/pharmacology ; Soybean Oil/administration & dosage ; Soybean Oil/pharmacology
Czasopismo naukowe
Tytuł :
Oscillations of C-peptide in the euglycemic clamp and their effect on the pharmacodynamic assessment of insulin preparations.
Autorzy :
Liu H; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China.
Yu H; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China.
Qiao J; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China.
Sun L; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China.
Li J; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China.
Tan H; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China.
Yu Y; Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China.
Pokaż więcej
Źródło :
Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2021 Aug; Vol. 35 (4), pp. 771-780. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Glucose/*drug effects
Hypoglycemic Agents/*pharmacology
Insulin Aspart/*pharmacology
Adolescent ; Adult ; Area Under Curve ; C-Peptide/metabolism ; Glucose Clamp Technique ; Humans ; Hypoglycemic Agents/administration & dosage ; Insulin Aspart/administration & dosage ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens.
Autorzy :
Cai W; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.; Department of Biomedical Sciences, New York Institute of Technology, College of Osteopathic Medicine, Old Westbury, NY.
Zhang X; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Batista TM; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
García-Martín R; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Softic S; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.; Department of Pediatrics, University of Kentucky, College of Medicine, Lexington, KY.
Wang G; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Ramirez AK; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Konishi M; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
O'Neill BT; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA.; Division of Endocrinology and Metabolism, Fraternal Order of Eagles Diabetes Research Center, University of Iowa Carver College of Medicine, Iowa City, IA.
Kim JH; Program in Molecular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.; Department of Food Science and Biotechnology, Sungshin University, Seoul, South Korea.
Kim JK; Program in Molecular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.; Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, MA.
Kahn CR; Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA .
Pokaż więcej
Źródło :
Diabetes [Diabetes] 2021 Aug; Vol. 70 (8), pp. 1857-1873. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation/*drug effects
Hippocampus/*metabolism
Hypothalamus/*metabolism
Insulin/*pharmacology
Lipogenesis/*physiology
Nucleus Accumbens/*metabolism
Animals ; Astrocytes/drug effects ; Astrocytes/metabolism ; Glucose Clamp Technique ; Hippocampus/drug effects ; Hypothalamus/drug effects ; Lipogenesis/drug effects ; Male ; Mice ; Neurons/drug effects ; Neurons/metabolism ; Nucleus Accumbens/drug effects
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies