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Tytuł :
The usefulness of the percentage of immature granulocytes in predicting in-hospital mortality in patients with upper gastrointestinal bleeding.
Autorzy :
Narcı H; Mersin University, Faculty of Medicine, Department of Emergency Medicine, Mersin, Turkey. Electronic address: .
Berkeşoğlu M; Mersin University, Faculty of Medicine, Department of General Surgery, Mersin, Turkey.
Üçbilek E; Associate professor, Mersin University, Faculty of Medicine, Department of Gastroenterology, Mersin, Turkey.
Ayrık C; Mersin University, Faculty of Medicine, Department of Emergency Medicine, Mersin, Turkey.
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Źródło :
The American journal of emergency medicine [Am J Emerg Med] 2021 Aug; Vol. 46, pp. 646-650. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Prognosis*
Granulocytes/*classification
Hemorrhage/*blood
Hemorrhage/*mortality
Upper Gastrointestinal Tract/*physiopathology
Aged ; Aged, 80 and over ; Area Under Curve ; Biomarkers/analysis ; Biomarkers/blood ; Female ; Granulocytes/immunology ; Hospital Mortality/trends ; Humans ; Male ; Middle Aged ; ROC Curve ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Evaluation of the accuracy of immature granulocyte percentage in predicting pediatric serious bacterial infection.
Autorzy :
Güngör A; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Göktuğ A; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Tekeli A; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Bodur İ; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Öztürk B; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Güneylioğlu MM; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Yaradılmış RM; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Akca Çağlar A; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Tuygun N; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Karacan CD; Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
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Źródło :
International journal of laboratory hematology [Int J Lab Hematol] 2021 Aug; Vol. 43 (4), pp. 632-637. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Granulocytes*
Severity of Illness Index*
C-Reactive Protein/*metabolism
Meningitis, Bacterial/*blood
Sepsis/*blood
Biomarkers/blood ; Emergency Service, Hospital ; Female ; Humans ; Infant ; Leukocyte Count ; Male ; Predictive Value of Tests ; Retrospective Studies
Czasopismo naukowe
Tytuł :
High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19.
Autorzy :
Lourda M; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden; .; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, 171 77, Stockholm, Sweden.
Dzidic M; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Hertwig L; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Bergsten H; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Palma Medina LM; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Sinha I; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, 171 77, Stockholm, Sweden.
Kvedaraite E; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, 171 77, Stockholm, Sweden.
Chen P; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Muvva JR; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Gorin JB; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Cornillet M; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Emgård J; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Moll K; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
García M; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Maleki KT; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Klingström J; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Michaëlsson J; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Flodström-Tullberg M; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Brighenti S; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Buggert M; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Mjösberg J; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Malmberg KJ; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Sandberg JK; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Henter JI; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, 171 77, Stockholm, Sweden.; Theme of Children's Health, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Folkesson E; Department of Infectious Diseases, Karolinska University Hospital, 171 77, Stockholm, Sweden.; Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, 171 77, Stockholm, Sweden.
Gredmark-Russ S; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.; Department of Infectious Diseases, Karolinska University Hospital, 171 77, Stockholm, Sweden.
Sönnerborg A; Department of Infectious Diseases, Karolinska University Hospital, 171 77, Stockholm, Sweden.; Division of Infectious Diseases and Dermatology, Department of Medicine Huddinge, Karolinska Institutet, 141 52, Stockholm, Sweden.
Eriksson LI; Department of Physiology and Pharmacology, Section for Anesthesiology and Intensive Care, Karolinska Institutet, 171 77, Stockholm, Sweden.; Function Perioperative Medicine and Intensive Care, Karolinska University Hospital, 171 77, Stockholm, Sweden.
Rooyackers O; Function Perioperative Medicine and Intensive Care, Karolinska University Hospital, 171 77, Stockholm, Sweden.; Department of Clinical Interventions and Technology, Division for Anesthesiology and Intensive Care, Karolinska Institutet, 171 77, Stockholm, Sweden.
Aleman S; Department of Infectious Diseases, Karolinska University Hospital, 171 77, Stockholm, Sweden.; Division of Infectious Diseases and Dermatology, Department of Medicine Huddinge, Karolinska Institutet, 141 52, Stockholm, Sweden.
Strålin K; Department of Infectious Diseases, Karolinska University Hospital, 171 77, Stockholm, Sweden.; Division of Infectious Diseases and Dermatology, Department of Medicine Huddinge, Karolinska Institutet, 141 52, Stockholm, Sweden.
Ljunggren HG; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Björkström NK; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Svensson M; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Ponzetta A; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Norrby-Teglund A; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
Chambers BJ; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 52, Stockholm, Sweden.
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Corporate Authors :
Karolinska KI/K COVID-19 Study Group
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Oct 05; Vol. 118 (40).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*immunology
Granulocytes/*immunology
COVID-19/blood ; COVID-19/diagnosis ; COVID-19/physiopathology ; Granulocytes/cytology ; Humans ; Immunity, Innate ; Immunophenotyping ; Leukocyte Count ; Lung/physiopathology ; Models, Biological ; Organ Dysfunction Scores ; SARS-CoV-2 ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Systemic and mucosal mobilization of granulocyte subsets during lentiviral infection.
Autorzy :
Jones R; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Manickam C; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Ram DR; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Kroll K; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Hueber B; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Woolley G; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Shah SV; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Smith S; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Varner V; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Reeves RK; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Ragon Institute of Massachusetts General Hospital, MIT, and Harvard, Cambridge, MA, USA.; Division of Innate and Comparative Immunology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, USA.
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Źródło :
Immunology [Immunology] 2021 Oct; Vol. 164 (2), pp. 348-357. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Granulocytes/*immunology
Lentivirus Infections/*immunology
Macaca mulatta/*immunology
Mucous Membrane/*immunology
Animals ; Basophils/immunology ; Basophils/virology ; Eosinophils/immunology ; Eosinophils/virology ; Flow Cytometry/methods ; Granulocytes/virology ; HIV Infections/immunology ; HIV Infections/virology ; Leukocyte Count/methods ; Mucous Membrane/virology ; Neutrophils/immunology ; Neutrophils/virology ; Receptors, IgG/immunology
Czasopismo naukowe
Tytuł :
Inflammasome Activation in Children With Kawasaki Disease and Multisystem Inflammatory Syndrome.
Autorzy :
Wang WT; Division of Cardiology, Department of Medicine (W.-T.W., M.H., J.Y.-J.S.), University of California, San Diego, La Jolla.
He M; Division of Cardiology, Department of Medicine (W.-T.W., M.H., J.Y.-J.S.), University of California, San Diego, La Jolla.
Shimizu C; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.
Croker BA; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.
Hoffman HM; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.; Rady Children's Hospital, San Diego, CA (H.M.H., A.H.T., J.C.B.).
Tremoulet AH; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.; Rady Children's Hospital, San Diego, CA (H.M.H., A.H.T., J.C.B.).
Burns JC; Department of Pediatrics (C.S., B.A.C., H.M.H., A.H.T., J.C.B.), University of California, San Diego, La Jolla.; Rady Children's Hospital, San Diego, CA (H.M.H., A.H.T., J.C.B.).
Shyy JY; Division of Cardiology, Department of Medicine (W.-T.W., M.H., J.Y.-J.S.), University of California, San Diego, La Jolla.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Sep; Vol. 41 (9), pp. 2509-2511. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji :
Comparative Study; Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*immunology
Granulocytes/*immunology
Inflammasomes/*immunology
Inflammation Mediators/*immunology
Mucocutaneous Lymph Node Syndrome/*immunology
NLR Family, Pyrin Domain-Containing 3 Protein/*immunology
Neutrophils/*immunology
Systemic Inflammatory Response Syndrome/*immunology
Adaptor Proteins, Signal Transducing/blood ; Adaptor Proteins, Signal Transducing/genetics ; COVID-19/blood ; COVID-19/genetics ; Caspase 1/blood ; Caspase 1/genetics ; Caspases, Initiator/blood ; Caspases, Initiator/genetics ; Gene Expression Profiling ; Granulocytes/metabolism ; Humans ; Inflammasomes/genetics ; Inflammasomes/metabolism ; Inflammation Mediators/blood ; Interleukin-1beta/blood ; Interleukin-1beta/genetics ; Mucocutaneous Lymph Node Syndrome/blood ; Mucocutaneous Lymph Node Syndrome/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Neutrophils/metabolism ; Systemic Inflammatory Response Syndrome/blood ; Systemic Inflammatory Response Syndrome/genetics ; Transcriptome
SCR Disease Name :
pediatric multisystem inflammatory disease, COVID-19 related
Raport
Tytuł :
Calcium activity in response to nAChR ligands in murine bone marrow granulocytes with different Gr-1 expression.
Autorzy :
Serov D; Institute of Cell Biophysics of the Russian Academy of Sciences, Pushchino, Russia.; Prokhorov General Physics Institute of the Russian Academy of Sciences, Russia.
Tikhonova I; Institute of Cell Biophysics of the Russian Academy of Sciences, Pushchino, Russia.
Safronova V; Institute of Cell Biophysics of the Russian Academy of Sciences, Pushchino, Russia.
Astashev M; Institute of Cell Biophysics of the Russian Academy of Sciences, Pushchino, Russia.; Prokhorov General Physics Institute of the Russian Academy of Sciences, Russia.
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Źródło :
Cell biology international [Cell Biol Int] 2021 Jul; Vol. 45 (7), pp. 1533-1545. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antigens, Ly/*metabolism
Bone Marrow Cells/*drug effects
Calcium/*metabolism
Calcium Signaling/*drug effects
Cholinergic Agents/*pharmacology
Granulocytes/*drug effects
Receptors, Nicotinic/*drug effects
Animals ; Bone Marrow Cells/metabolism ; Cells, Cultured ; Granulocytes/metabolism ; Ligands ; Male ; Mice, Inbred BALB C ; Nicotine/pharmacology ; Nicotinic Agonists/pharmacology ; Nicotinic Antagonists/pharmacology ; Receptors, Nicotinic/metabolism
Czasopismo naukowe
Tytuł :
Cold Atmospheric Plasma Promotes the Immunoreactivity of Granulocytes In Vitro.
Autorzy :
Kupke LS; Department of Anesthesiology, University Hospital Regensburg, 93053 Regensburg, Germany.; Department of Dermatology, University Hospital Regensburg, 93053 Regensburg, Germany.
Arndt S; Department of Dermatology, University Hospital Regensburg, 93053 Regensburg, Germany.
Lenzer S; Department of Anesthesiology, University Hospital Regensburg, 93053 Regensburg, Germany.; Department of Dermatology, University Hospital Regensburg, 93053 Regensburg, Germany.
Metz S; Department of Anesthesiology, University Hospital Regensburg, 93053 Regensburg, Germany.
Unger P; Department of Dermatology, University Hospital Regensburg, 93053 Regensburg, Germany.
Zimmermann JL; Terraplasma Medical GmbH, 85748 Garching, Germany.
Bosserhoff AK; Emil-Fischer-Center, Institute of Biochemistry, University of Erlangen-Nuernberg (FAU), 91054 Erlangen, Germany.
Gruber M; Department of Anesthesiology, University Hospital Regensburg, 93053 Regensburg, Germany.
Karrer S; Department of Dermatology, University Hospital Regensburg, 93053 Regensburg, Germany.
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Źródło :
Biomolecules [Biomolecules] 2021 Jun 17; Vol. 11 (6). Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Granulocytes/*immunology
Integrins/*immunology
Plasma Gases/*pharmacology
Reactive Nitrogen Species/*immunology
Reactive Oxygen Species/*immunology
Selectins/*immunology
Apoptosis/drug effects ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/immunology ; Granulocytes/cytology ; Humans
Czasopismo naukowe
Tytuł :
STAT1 Is Required for Decreasing Accumulation of Granulocytic Cells via IL-17 during Initial Steps of Colitis-Associated Cancer.
Autorzy :
Delgado-Ramirez Y; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
Baltazar-Perez I; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
Martinez Y; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
Callejas BE; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
Medina-Andrade I; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.; Laboratorio Nacional en Salud, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
Olguín JE; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.; Laboratorio Nacional en Salud, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
Delgado-Buenrostro NL; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
Chirino YI; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
Terrazas LI; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.; Laboratorio Nacional en Salud, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
Leon-Cabrera S; Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.; Carrera de Médico Cirujano, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo. De México 54090, Mexico.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 19; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article
MeSH Terms :
Colitis-Associated Neoplasms/*etiology
Granulocytes/*pathology
Interleukin-17/*physiology
STAT1 Transcription Factor/*physiology
Animals ; Antibodies, Neutralizing/administration & dosage ; Colitis-Associated Neoplasms/pathology ; Colitis-Associated Neoplasms/physiopathology ; Disease Progression ; Female ; Granulocytes/immunology ; Interleukin-17/antagonists & inhibitors ; Interleukin-17/immunology ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; Myeloid-Derived Suppressor Cells/immunology ; Myeloid-Derived Suppressor Cells/pathology ; Neoplasms, Experimental/etiology ; Neoplasms, Experimental/pathology ; Neoplasms, Experimental/physiopathology ; STAT1 Transcription Factor/deficiency ; STAT1 Transcription Factor/genetics ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells.
Autorzy :
Dean MJ; Louisiana State University Cancer Center, New Orleans, LA, United States.
Ochoa JB; Department of Surgery, Ochsner Medical Center, New Orleans, LA, United States.
Sanchez-Pino MD; Louisiana State University Cancer Center, New Orleans, LA, United States.; Department of Genetics, LSU Health, New Orleans, LA, United States.
Zabaleta J; Louisiana State University Cancer Center, New Orleans, LA, United States.; Department of Pediatrics, LSU Health, New Orleans, LA, United States.
Garai J; Louisiana State University Cancer Center, New Orleans, LA, United States.
Del Valle L; Louisiana State University Cancer Center, New Orleans, LA, United States.; Department of Pathology LSU Health, New Orleans, LA, United States.
Wyczechowska D; Louisiana State University Cancer Center, New Orleans, LA, United States.
Baiamonte LB; Tissue Biorepository, Ochsner Medical Center, New Orleans, LA, United States.
Philbrook P; Louisiana State University Cancer Center, New Orleans, LA, United States.; Department of Genetics, LSU Health, New Orleans, LA, United States.
Majumder R; Department of Biochemistry, LSU Health, New Orleans, LA, United States.
Vander Heide RS; Department of Pathology LSU Health, New Orleans, LA, United States.
Dunkenberger L; Louisiana State University Cancer Center, New Orleans, LA, United States.
Thylur RP; Louisiana State University Cancer Center, New Orleans, LA, United States.
Nossaman B; Department of Surgery, Ochsner Medical Center, New Orleans, LA, United States.
Roberts WM; Department of Internal Medicine, Ochsner Medical Center, New Orleans, LA, United States.
Chapple AG; Louisiana State University Cancer Center, New Orleans, LA, United States.; School of Public Health, LSU Health, New Orleans, LA, United States.
Wu J; Department of Genetics, LSU Health, New Orleans, LA, United States.
Hicks C; Department of Genetics, LSU Health, New Orleans, LA, United States.
Collins J; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Luke B; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Johnson R; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.
Koul HK; Louisiana State University Cancer Center, New Orleans, LA, United States.; Department of Biochemistry, LSU Health, New Orleans, LA, United States.
Rees CA; Division of Emergency Medicine, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA, United States.
Morris CR; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, Children's Healthcare of Atlanta, Atlanta, GA, United States.
Garcia-Diaz J; Tissue Biorepository, Ochsner Medical Center, New Orleans, LA, United States.
Ochoa AC; Louisiana State University Cancer Center, New Orleans, LA, United States.; Department of Pediatrics, LSU Health, New Orleans, LA, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Jul 14; Vol. 12, pp. 695972. Date of Electronic Publication: 2021 Jul 14 (Print Publication: 2021).
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*immunology
Granulocytes/*immunology
Myeloid-Derived Suppressor Cells/*immunology
SARS-CoV-2/*immunology
Adult ; Aged ; Aged, 80 and over ; Antiviral Agents/administration & dosage ; Arginase/antagonists & inhibitors ; Arginase/metabolism ; Arginine/administration & dosage ; Arginine/blood ; Arginine/metabolism ; Asymptomatic Infections ; COVID-19/blood ; COVID-19/diagnosis ; COVID-19/drug therapy ; Case-Control Studies ; Drug Therapy, Combination/methods ; Enzyme Inhibitors/administration & dosage ; Female ; Granulocytes/metabolism ; Healthy Volunteers ; Humans ; Interferon Type I/metabolism ; Male ; Middle Aged ; Myeloid-Derived Suppressor Cells/metabolism ; Severity of Illness Index ; Signal Transduction/immunology ; T-Lymphocytes/immunology
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Characterization of low-density granulocytes in COVID-19.
Autorzy :
Cabrera LE; Zoonosis Unit, Department of Virology, University of Helsinki, Helsinki, Finland.
Pekkarinen PT; Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland.; Division of Intensive Care Medicine, Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Alander M; Department of Internal Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Nowlan KHA; Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland.
Nguyen NA; Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland.
Jokiranta S; Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland.
Kuivanen S; Zoonosis Unit, Department of Virology, University of Helsinki, Helsinki, Finland.
Patjas A; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Inflammation Center, Division of Infectious Diseases, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Mero S; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Pakkanen SH; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Heinonen S; New Children's Hospital, Pediatric Research Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Kantele A; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Inflammation Center, Division of Infectious Diseases, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Vapalahti O; Zoonosis Unit, Department of Virology, University of Helsinki, Helsinki, Finland.; Division of Virology and Immunology, HUSLAB Clinical Microbiology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.; Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland.
Kekäläinen E; Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland.; Translational Immunology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Division of Virology and Immunology, HUSLAB Clinical Microbiology, HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland.
Strandin T; Zoonosis Unit, Department of Virology, University of Helsinki, Helsinki, Finland.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Jul 06; Vol. 17 (7), pp. e1009721. Date of Electronic Publication: 2021 Jul 06 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*immunology
Granulocytes/*classification
Acute Disease ; Adult ; Aged ; COVID-19/blood ; Case-Control Studies ; Cohort Studies ; Convalescence ; Disease Progression ; Female ; Follow-Up Studies ; Granulocytes/cytology ; Humans ; Immune Tolerance/immunology ; Male ; Middle Aged ; Scavenger Receptors, Class E/analysis ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Serotonin and dopamine receptors profile on peripheral immune cells from patients with temporal lobe epilepsy.
Autorzy :
Vieira ÉLM; Centre for Addiction and Mental Health - CAMH, Toronto M5T 1R8, Canada.
da Silva MCM; Laboratório de Neurofarmacologia, Departamento de Farmacologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Gonçalves AP; Programa de Neurociências, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Martins GL; Laboratório de Neurofarmacologia, Departamento de Farmacologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Teixeira AL; Instituto de Ensino e Pesquisa, Santa Casa BH, Belo Horizonte 30260-070, Brazil; Neuropsychiatry Program and Immuno-Psychiatry Lab, Department of Psychiatry and Behavioral Sciences, UT Health Houston, 1941 East Road, Houston, TX 77054, USA.
de Oliveira ACP; Laboratório de Neurofarmacologia, Departamento de Farmacologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil; Programa de Neurociências, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil. Electronic address: .
Reis HJ; Laboratório de Neurofarmacologia, Departamento de Farmacologia, ICB, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil; Programa de Neurociências, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil. Electronic address: .
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Źródło :
Journal of neuroimmunology [J Neuroimmunol] 2021 May 15; Vol. 354, pp. 577534. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epilepsy, Temporal Lobe/*immunology
Granulocytes/*immunology
Monocytes/*immunology
Receptors, Dopamine/*immunology
Receptors, Serotonin/*immunology
Adult ; Epilepsy, Temporal Lobe/metabolism ; Female ; Granulocytes/metabolism ; Humans ; Male ; Middle Aged ; Monocytes/metabolism ; Receptors, Dopamine/metabolism ; Receptors, Serotonin/metabolism
Czasopismo naukowe
Tytuł :
HDN-1 induces cell differentiation toward apoptosis in promyelocytic leukemia cells depending on its selective effect on client proteins of Hsp90.
Autorzy :
Qi X; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
Zhang X; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
Liu X; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
Tang W; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
Dai J; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
Chen A; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
Lin Q; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
Zhu T; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China; Open Studio for Druggability Research of Marine Natural Products, Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Aoshanwei, Jimo, Qingdao 266237, PR China.
Li J; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China; Open Studio for Druggability Research of Marine Natural Products, Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Aoshanwei, Jimo, Qingdao 266237, PR China. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Apr 15; Vol. 417, pp. 115459. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Cell Differentiation/*drug effects
Diketopiperazines/*pharmacology
Disulfides/*pharmacology
Granulocytes/*drug effects
HSP90 Heat-Shock Proteins/*antagonists & inhibitors
Leukemia, Promyelocytic, Acute/*drug therapy
Benzoquinones/pharmacology ; CCAAT-Enhancer-Binding Protein-beta/genetics ; CCAAT-Enhancer-Binding Protein-beta/metabolism ; Cell Lineage ; Core Binding Factor Alpha 2 Subunit/genetics ; Core Binding Factor Alpha 2 Subunit/metabolism ; Gene Expression Regulation, Leukemic ; Granulocytes/metabolism ; Granulocytes/pathology ; HL-60 Cells ; HSP90 Heat-Shock Proteins/genetics ; HSP90 Heat-Shock Proteins/metabolism ; Humans ; Lactams, Macrocyclic/pharmacology ; Leukemia, Promyelocytic, Acute/genetics ; Leukemia, Promyelocytic, Acute/metabolism ; Leukemia, Promyelocytic, Acute/pathology ; Oncogene Proteins, Fusion/genetics ; Oncogene Proteins, Fusion/metabolism ; RUNX1 Translocation Partner 1 Protein/genetics ; RUNX1 Translocation Partner 1 Protein/metabolism
Czasopismo naukowe
Tytuł :
Neonatal low-density granulocytes internalize and kill bacteria but suppress monocyte function using extracellular DNA.
Autorzy :
Seman BG; Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506, USA.
Vance JK; Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506, USA.
Akers SM; Department of Pediatrics, West Virginia University School of Medicine, Morgantown, WV 26506, USA.
Robinson CM; Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV 26506, USA .; Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV 26506, USA.
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Źródło :
Journal of cell science [J Cell Sci] 2021 Mar 05; Vol. 134 (5). Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Granulocytes*
Monocytes*
Bacteria ; DNA ; Humans ; Infant, Newborn ; Leukocyte Count ; Neutrophils
Czasopismo naukowe
Tytuł :
Activated low-density granulocytes in peripheral and intervillous blood and neutrophil inflammation in placentas from SLE pregnancies.
Autorzy :
Stockfelt M; Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Larsson G; Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Engström H; Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Puttonen H; Department of Pathology, Sahlgrenska University Hospital, Goteborg, Sweden.
Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; UK Dementia Research, Institute at UCL, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
Sjöwall C; Division of Inflammation and Infection, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Strevens H; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Skåne University Hospital, Lund, Sweden.
Jönsen A; Department of Clinical Sciences, Rheumatology, Lund University, Lund, Sweden.
Bengtsson AA; Department of Clinical Sciences, Rheumatology, Lund University, Lund, Sweden.
Majczuk Sennström M; Department of Womens and Childrens Health, Division for Obstetrics and Gynecology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.
Zickert A; Division of Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Svenungsson E; Division of Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Gunnarsson I; Division of Rheumatology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Trysberg E; Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Jacobsson B; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Goteborg, Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynecology, Gothenburg, Sweden.; Department of Genetics and Bioinformatics, Domain of Health Data and Digitalisation, Institute of Public Health, Oslo, Norway.
Hultgård Ekwall AK; Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Christenson K; Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy at the University of Gothenburg, Goteborg, Sweden.
Bylund J; Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy at the University of Gothenburg, Goteborg, Sweden.
Svensson MND; Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Lundell AC; Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden .
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Źródło :
Lupus science & medicine [Lupus Sci Med] 2021 Mar; Vol. 8 (1).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Granulocytes*
Lupus Erythematosus, Systemic*
Neutrophils*
Adult ; Cesarean Section ; Female ; Heparin, Low-Molecular-Weight ; Humans ; Infant, Newborn ; Inflammation ; Placenta ; Pregnancy ; Pregnancy Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Transcriptional Diversity and Niche-Specific Distribution of Leukocyte Populations during Staphylococcus aureus Craniotomy-Associated Biofilm Infection.
Autorzy :
Aldrich AL; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198.
Horn CM; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198.
Heim CE; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198.
Korshoj LE; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198.
Kielian T; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198 .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Feb 15; Vol. 206 (4), pp. 751-765. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Craniotomy*
Biofilms/*growth & development
Granulocytes/*immunology
Myeloid-Derived Suppressor Cells/*immunology
Staphylococcal Infections/*immunology
Staphylococcus aureus/*physiology
Transcription, Genetic/*immunology
Animals ; Female ; Granulocytes/pathology ; Male ; Mice ; Myeloid-Derived Suppressor Cells/pathology ; Staphylococcal Infections/pathology
Czasopismo naukowe
Tytuł :
Harmful Effects of Granulocytic Myeloid-Derived Suppressor Cells on Tuberculosis Caused by Hypervirulent Mycobacteria.
Autorzy :
Barbosa Bomfim CC; Departamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Pinheiro Amaral E; Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Santiago-Carvalho I; Departamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Almeida Santos G; Departamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Machado Salles É; Departamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Hastreiter AA; Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, Brazil.
Silva do Nascimento R; Departamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Almeida FM; Laboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, Brazil.
Lopes Biá Ventura Simão T; Laboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, Brazil.
Linhares Rezende A; Laboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, Brazil.
Hiroyuki Hirata M; Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, Brazil.
Ambrósio Fock R; Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, Brazil.
Álvarez JM; Departamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Lasunskaia EB; Laboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, Brazil.
D'Império Lima MR; Departamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2021 Feb 13; Vol. 223 (3), pp. 494-507.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Granulocytes*/immunology
Mycobacterium bovis*/pathogenicity
Myeloid-Derived Suppressor Cells*/immunology
Myeloid-Derived Suppressor Cells*/pathology
Tuberculosis*/pathology
Lung/*metabolism
Animals ; Antigens, Ly ; Bone Marrow ; CD11b Antigen ; Cell Proliferation ; Disease Models, Animal ; Immunomodulation ; Lung/pathology ; Mice ; Mice, Inbred C57BL ; Myeloid Cells ; Neutrophils
Czasopismo naukowe
Tytuł :
Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus.
Autorzy :
Bashant KR; NIAMS, National Institutes of Health, Bethesda, Maryland, USA.; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.
Aponte AM; NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Randazzo D; NIAMS, National Institutes of Health, Bethesda, Maryland, USA.
Rezvan Sangsari P; NIBIB, National Institutes of Health, Bethesda, Maryland, USA.
Wood AJ; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.
Bibby JA; NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
West EE; NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Vassallo A; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.
Manna ZG; NIAMS, National Institutes of Health, Bethesda, Maryland, USA.
Playford MP; NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Jordan N; Rheumatology Department, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Hasni S; NIAMS, National Institutes of Health, Bethesda, Maryland, USA.
Gucek M; NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Kemper C; NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Conway Morris A; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.
Morgan NY; NIBIB, National Institutes of Health, Bethesda, Maryland, USA.
Toepfner N; Department of Pediatrics/Carl Gustav Carus University Hospital, Technical University Dresden, Dresden, Sachsen, Germany.
Guck J; Biological Optomechanics Division, Max Planck Institute for the Science of Light, Erlangen, Bayern, Germany.
Mehta NN; NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Chilvers ER; National Heart and Lung Institute, London, UK.
Summers C; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.
Kaplan MJ; NIAMS, National Institutes of Health, Bethesda, Maryland, USA .
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Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2021 Feb; Vol. 80 (2), pp. 209-218. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Granulocytes/*pathology
Lupus Erythematosus, Systemic/*immunology
Membrane Proteins/*analysis
Neutrophils/*pathology
Proteome/*analysis
Case-Control Studies ; Genetic Heterogeneity ; Granulocytes/physiology ; Humans ; Interferon Type I/metabolism ; Lupus Erythematosus, Systemic/blood ; Microvessels/metabolism ; Neutrophils/physiology ; Phosphorylation ; Proteomics
Czasopismo naukowe
Tytuł :
Diacetoxyscirpenol-induced heterophil extracellular traps contribute to the immune toxicity of liver injury in chickens.
Autorzy :
Wu D; School of Life Sciences and Engineering, Foshan University, Foshan, 528225, Guangdong Province, China; Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, Jilin Province, PR China.
Li S; School of Life Sciences and Engineering, Foshan University, Foshan, 528225, Guangdong Province, China; Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, Jilin Province, PR China.
Li P; School of Life Sciences and Engineering, Foshan University, Foshan, 528225, Guangdong Province, China.
Jiang A; School of Life Sciences and Engineering, Foshan University, Foshan, 528225, Guangdong Province, China; Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, Jilin Province, PR China.
Liu Z; School of Life Sciences and Engineering, Foshan University, Foshan, 528225, Guangdong Province, China; Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, Jilin Province, PR China.
Zhang Y; School of Life Sciences and Engineering, Foshan University, Foshan, 528225, Guangdong Province, China; Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, Jilin Province, PR China.
Wang J; Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, Jilin Province, PR China.
Yang Z; School of Life Sciences and Engineering, Foshan University, Foshan, 528225, Guangdong Province, China.
Wei Z; School of Life Sciences and Engineering, Foshan University, Foshan, 528225, Guangdong Province, China. Electronic address: .
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 Feb; Vol. 148, pp. 111926. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article
MeSH Terms :
Chemical and Drug Induced Liver Injury/*immunology
Extracellular Traps/*drug effects
Granulocytes/*drug effects
Immunity, Innate/*drug effects
Trichothecenes/*toxicity
Animals ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury/pathology ; Chickens ; Granulocytes/metabolism ; Liver/pathology ; MAP Kinase Signaling System/physiology ; NADPH Oxidases/metabolism
Czasopismo naukowe
Tytuł :
Elevated circulating pro-inflammatory low-density granulocytes in adult-onset Still's disease.
Autorzy :
Liu Y; Department of Clinical Laboratory.
Xia C; Department of Clinical Laboratory.
Chen J; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China.
Fan C; Department of Clinical Laboratory.
He J; Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China.
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Źródło :
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2021 Jan 05; Vol. 60 (1), pp. 297-303.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Granulocytes*
Leukocytes, Mononuclear*
Still's Disease, Adult-Onset/*blood
Adult ; Female ; Flow Cytometry ; Humans ; Interleukin-6/blood ; Leukocyte Count ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
EFFICIENCY OF BONE MARROW PRECURSOR CELL COLONY-FORMING AS A PREDICTOR OF DISEASE COURSE IN PLASMA CELL MYELOMA PATIENTS WITH A HISTORY OF RADIATION EXPOSURE.
Autorzy :
Minchenko ZM; State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine.
Liubarets TF; State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine.
Balan VV; State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine.
Dmytrenko OO; State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine.
Shlyakhtichenko TY; State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine.
Moyseyenko VO; Bogomolets National Medical University of the Ministry of Health of Ukraine, 13 Tarasa Shevchenka Blvd., Kyiv, 01601, UkrainePrivate Higher Educational Institution «International Academy of Ecology and Medicine», 121 Kharkivske Hwy., Kyiv, 02000, Ukraine.
Silayev YO; State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine.
Bebeshko VG; State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine.
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Transliterated Title :
EFEKTYVNIST' KOLONIIeUTVORENNIa KLITYN-POPEREDNYKIV KISTKOVOGO MOZKU, IaK PROGNOSTYChNYĬ FAKTOR PEREBIGU PLAZMOKLITYNNOÏ MIIeLOMY U OSIB Z RADIATsIĬNYM ANAMNEZOM.
Źródło :
Problemy radiatsiinoi medytsyny ta radiobiolohii [Probl Radiac Med Radiobiol] 2020 Dec; Vol. 25, pp. 490-501.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols*
Chernobyl Nuclear Accident*
Bone Marrow Cells/*immunology
Granulocytes/*immunology
Macrophages/*immunology
Multiple Myeloma/*immunology
Radiation Exposure/*adverse effects
Adult ; Aged ; Antineoplastic Agents/therapeutic use ; Bone Marrow/drug effects ; Bone Marrow/immunology ; Bone Marrow/pathology ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/pathology ; Colony-Forming Units Assay ; Female ; Granulocytes/drug effects ; Granulocytes/pathology ; Humans ; Induced Pluripotent Stem Cells/drug effects ; Induced Pluripotent Stem Cells/immunology ; Induced Pluripotent Stem Cells/pathology ; Macrophages/drug effects ; Macrophages/pathology ; Male ; Middle Aged ; Multiple Myeloma/drug therapy ; Multiple Myeloma/etiology ; Multiple Myeloma/mortality ; Neoplasm Staging ; Remission Induction ; Stem Cells/drug effects ; Stem Cells/immunology ; Stem Cells/pathology ; Survival Analysis
Czasopismo naukowe

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