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Tytuł:
Functional Conservation of the Small GTPase Rho5/Rac1-A Tale of Yeast and Men.
Autorzy:
Bischof L; AG Genetik, Fachbereich Biologie/Chemie, University of Osnabrück, Barbarastrasse 11, D-49076 Osnabrück, Germany.
Schweitzer F; AG Genetik, Fachbereich Biologie/Chemie, University of Osnabrück, Barbarastrasse 11, D-49076 Osnabrück, Germany.
Heinisch JJ; AG Genetik, Fachbereich Biologie/Chemie, University of Osnabrück, Barbarastrasse 11, D-49076 Osnabrück, Germany.
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Źródło:
Cells [Cells] 2024 Mar 07; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Saccharomyces cerevisiae*/metabolism
Monomeric GTP-Binding Proteins*/metabolism
Male ; Humans ; Oxidative Stress ; rho GTP-Binding Proteins/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Rab37 mediates trafficking and membrane presentation of PD-1 to sustain T cell exhaustion in lung cancer.
Autorzy:
Kuo WT; Department of Pharmacology, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 701, Taiwan.
Kuo IY; Department of Pharmacology, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 701, Taiwan.; Department of Biotechnology, College of Biomedical Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
Hsieh HC; Institute of Basic Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wu ST; Department of Pharmacology, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 701, Taiwan.
Su WC; Division of Oncology, Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wang YC; Department of Pharmacology, College of Medicine, National Cheng Kung University, No. 1, University Road, Tainan, 701, Taiwan. .; Institute of Basic Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan. .
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Źródło:
Journal of biomedical science [J Biomed Sci] 2024 Feb 07; Vol. 31 (1), pp. 20. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms*/pathology
Monomeric GTP-Binding Proteins*/metabolism
Animals ; Humans ; Mice ; CD8-Positive T-Lymphocytes/metabolism ; Hepatitis A Virus Cellular Receptor 2/metabolism ; Leukocytes, Mononuclear/metabolism ; Mice, Knockout ; Programmed Cell Death 1 Receptor ; rab GTP-Binding Proteins ; T-Cell Exhaustion ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Small GTPase Rab7 Regulates Antigen Processing in B Cells in a Possible Interplay with Autophagy Machinery.
Autorzy:
Runsala M; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, 20014 Turku, Finland.; InFLAMES Research Flagship, University of Turku, 20014 Turku, Finland.; Turku Bioscience, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
Kuokkanen E; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, 20014 Turku, Finland.
Uski E; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, 20014 Turku, Finland.
Šuštar V; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, 20014 Turku, Finland.
Balci MÖ; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, 20014 Turku, Finland.; InFLAMES Research Flagship, University of Turku, 20014 Turku, Finland.; Turku Bioscience, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
Rajala J; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, 20014 Turku, Finland.
Paavola V; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, 20014 Turku, Finland.
Mattila PK; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, 20014 Turku, Finland.; InFLAMES Research Flagship, University of Turku, 20014 Turku, Finland.; Turku Bioscience, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
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Źródło:
Cells [Cells] 2023 Nov 02; Vol. 12 (21). Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigen Presentation*
rab7 GTP-Binding Proteins*
rab GTP-Binding Proteins/metabolism ; B-Lymphocytes ; Autophagy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tissue-specific expression differences in Ras-related GTP-binding proteins in male rats.
Autorzy:
Kincheloe GN; Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Roberson PA; Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Jefferson LS; Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Kimball SR; Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania, USA.
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Źródło:
Physiological reports [Physiol Rep] 2024 Feb; Vol. 12 (3), pp. e15928.
Typ publikacji:
Journal Article
MeSH Terms:
Signal Transduction*/physiology
Monomeric GTP-Binding Proteins*/genetics
Monomeric GTP-Binding Proteins*/chemistry
Monomeric GTP-Binding Proteins*/metabolism
Male ; Rats ; Animals ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Amino Acids/metabolism ; RNA, Messenger/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The eukaryotic-like characteristics of small GTPase, roadblock and TRAPPC3 proteins from Asgard archaea.
Autorzy:
Tran LT; Research Institute for Interdisciplinary Science, Okayama University, Okayama, 700-8530, Japan.
Akıl C; Research Institute for Interdisciplinary Science, Okayama University, Okayama, 700-8530, Japan.; Division of Structural Biology, University of Oxford, Oxford, England.
Senju Y; Research Institute for Interdisciplinary Science, Okayama University, Okayama, 700-8530, Japan.
Robinson RC; Research Institute for Interdisciplinary Science, Okayama University, Okayama, 700-8530, Japan. .; School of Biomolecular Science and Engineering (BSE), Vidyasirimedhi Institute of Science and Technology (VISTEC), Rayong, 21210, Thailand. .
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Źródło:
Communications biology [Commun Biol] 2024 Mar 12; Vol. 7 (1), pp. 273. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Monomeric GTP-Binding Proteins*/chemistry
Archaea/metabolism ; Protein Transport
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Native architecture of a human GBP1 defense complex for cell-autonomous immunity to infection.
Autorzy:
Zhu S; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Bradfield CJ; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Maminska A; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Park ES; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Kim BH; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Kumar P; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Huang S; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Kim M; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Zhang Y; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA.
Bewersdorf J; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Nanobiology Institute, West Haven, CT 06477, USA.
MacMicking JD; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar; Vol. 383 (6686), pp. eabm9903. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
GTP-Binding Proteins*/chemistry
Cell Membrane*/chemistry
Cell Membrane*/immunology
Innate Immunity Recognition*
Bacterial Infections*/immunology
Bacteria*/immunology
Humans ; Cytokines/chemistry ; Electron Microscope Tomography ; Guanosine Triphosphate/chemistry ; Hydrolysis ; Immunity, Cellular ; Cryoelectron Microscopy ; Gasdermins/chemistry ; Phosphate-Binding Proteins/chemistry ; Protein Conformation ; Caspases, Initiator/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Guanylate-binding protein 1 acts as a pro-viral factor for the life cycle of hepatitis C virus.
Autorzy:
Bender D; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
Koulouri A; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
Wen X; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
Glitscher M; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
Schollmeier A; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
Fernandes da Costa L; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
Murra RO; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
Carra GP; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
Haberger V; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
Praefcke GJK; Paul-Ehrlich-Institut, Department Haematology and Transfusion Medicine, Langen, Germany.
Hildt E; Paul-Ehrlich-Institut, Department of Virology, Langen, Germany.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Feb 05; Vol. 20 (2), pp. e1011976. Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Hepacivirus*/physiology
Hepatitis C*/genetics
GTP-Binding Proteins*/genetics
Humans ; Interferons ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
RND3 Potentiates Proinflammatory Activation through NOTCH Signaling in Activated Macrophages.
Autorzy:
de Ávila MJR; Medical School, Biomedicine Institute (IB-UCLM)/Biomedicine Unit, University of Castilla-La Mancha/CSIC, C/Almansa 14, 02008, Albacete, Spain.
López-López S; Medical School, Biomedicine Institute (IB-UCLM)/Biomedicine Unit, University of Castilla-La Mancha/CSIC, C/Almansa 14, 02008, Albacete, Spain.; Research Unit, University Hospital Complex of Albacete, C/Laurel s/n, 02008, Albacete, Spain.
García-Blázquez A; Medical School, Biomedicine Institute (IB-UCLM)/Biomedicine Unit, University of Castilla-La Mancha/CSIC, C/Almansa 14, 02008, Albacete, Spain.
Ruiz-García A; Biochemistry and Molecular Biology Branch, School of Pharmacy/CRIB/Biomedicine Unit, Department of Inorganic and Organic Chemistry and Biochemistry, University of Castilla-La Mancha/CSIC, Albacete, Spain.
González-Gómez MJ; Medical School, Biomedicine Institute (IB-UCLM)/Biomedicine Unit, University of Castilla-La Mancha/CSIC, C/Almansa 14, 02008, Albacete, Spain.
Nueda ML; Biochemistry and Molecular Biology Branch, School of Pharmacy/CRIB/Biomedicine Unit, Department of Inorganic and Organic Chemistry and Biochemistry, University of Castilla-La Mancha/CSIC, Albacete, Spain.
Baladrón V; Medical School, Biomedicine Institute (IB-UCLM)/Biomedicine Unit, University of Castilla-La Mancha/CSIC, C/Almansa 14, 02008, Albacete, Spain.
Pérez-Roger I; Department of Biomedical Sciences School of Health Sciences, University Cardenal Herrera-CEU, CEU Universities, 46115 Alfara del Patriarca, E-46115 Alfara del Patriarca, Valencia, Spain.
Poch E; Department of Biomedical Sciences School of Health Sciences, University Cardenal Herrera-CEU, CEU Universities, 46115 Alfara del Patriarca, E-46115 Alfara del Patriarca, Valencia, Spain.
Ballester-Lurbe B; Department of Biomedical Sciences School of Health Sciences, University Cardenal Herrera-CEU, CEU Universities, 46115 Alfara del Patriarca, E-46115 Alfara del Patriarca, Valencia, Spain.
García-Ramírez JJ; Medical School, Biomedicine Institute (IB-UCLM)/Biomedicine Unit, University of Castilla-La Mancha/CSIC, C/Almansa 14, 02008, Albacete, Spain.
Monsalve EM; Medical School, Biomedicine Institute (IB-UCLM)/Biomedicine Unit, University of Castilla-La Mancha/CSIC, C/Almansa 14, 02008, Albacete, Spain.
Díaz-Guerra MJM; Medical School, Biomedicine Institute (IB-UCLM)/Biomedicine Unit, University of Castilla-La Mancha/CSIC, C/Almansa 14, 02008, Albacete, Spain.
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Źródło:
Journal of immunology research [J Immunol Res] 2024 Feb 02; Vol. 2024, pp. 2264799. Date of Electronic Publication: 2024 Feb 02 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Macrophages*/metabolism
Signal Transduction*
rho GTP-Binding Proteins*/metabolism
Tumor Necrosis Factor-alpha/metabolism ; Animals ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differences in endosomal Rab gene expression between positive and negative COVID-19 patients.
Autorzy:
Atik N; Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, 40161, Indonesia. .
Wirawan F; Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia.
Amalia R; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, West Java, Indonesia.
Khairani AF; Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, 40161, Indonesia.
Pradini GW; Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, 40161, Indonesia.
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Źródło:
BMC research notes [BMC Res Notes] 2022 Jul 15; Vol. 15 (1), pp. 252. Date of Electronic Publication: 2022 Jul 15.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/genetics
rab5 GTP-Binding Proteins*/genetics
rab5 GTP-Binding Proteins*/metabolism
Endosomes/metabolism ; Gene Expression ; Humans ; rab GTP-Binding Proteins/genetics ; rab GTP-Binding Proteins/metabolism ; rab7 GTP-Binding Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clostridium n ovyi's Alpha-Toxin Changes Proteome and Phosphoproteome of HEp-2 Cells.
Autorzy:
Schweitzer T; Institute of Toxicology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.; Core Facility Proteomics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Genth H; Institute of Toxicology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Pich A; Institute of Toxicology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.; Core Facility Proteomics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 01; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 01.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Toxins*/metabolism
Clostridioides difficile*
Monomeric GTP-Binding Proteins*/metabolism
Bacterial Proteins/metabolism ; Enterotoxins/chemistry ; Glycosylation ; Proteome/metabolism ; Proteomics/methods ; Type C Phospholipases/metabolism ; rho GTP-Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comprehensive Analysis of Subcellular Localization, Immune Function and Role in Bacterial wilt Disease Resistance of Solanum lycopersicum Linn. ROP Family Small GTPases.
Autorzy:
Wang Q; School of Horticulture and Plant Protection, Yangzhou University, Yangzhou 225009, China.
Zhang D; School of Horticulture and Plant Protection, Yangzhou University, Yangzhou 225009, China.
Liu C; School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212021, China.
Li Y; Lingnan Guangdong Laboratory of Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 440307, China.
Miao Y; School of Horticulture and Plant Protection, Yangzhou University, Yangzhou 225009, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 27; Vol. 23 (17). Date of Electronic Publication: 2022 Aug 27.
Typ publikacji:
Journal Article
MeSH Terms:
Solanum lycopersicum*/genetics
Solanum lycopersicum*/metabolism
Monomeric GTP-Binding Proteins*/genetics
Ralstonia solanacearum*/metabolism
Disease Resistance/genetics ; Phylogeny ; rho GTP-Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mitochondria dysfunction in Charcot Marie Tooth 2B Peripheral Sensory Neuropathy.
Autorzy:
Gu Y; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA.; Department of Neurology, the Fourth Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.
Guerra F; Department of Biological and Environmental Sciences and Technologies (DiSTeBA), Università del Salento, Via Provinciale Lecce-Monteroni n. 165, 73100, Lecce, Italy.
Hu M; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA.
Pope A; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA.
Sung K; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA.
Yang W; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA.; Department of Neurology, Zhujiang Hospital of Southern Medical University Guangzhou, Guangzhou, 510280, Guangdong Sheng, China.
Jetha S; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA.
Shoff TA; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA.
Gunatilake T; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA.
Dahlkamp O; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA.
Shi LZ; Department of Bioengineering, University of California San Diego, La Jolla, 92093, CA, USA.
Manganelli F; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples 'Federico II', Via Sergio Pansini 5, 80131, Naples, Italy.
Nolano M; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples 'Federico II', Via Sergio Pansini 5, 80131, Naples, Italy.
Zhou Y; School of Biomedical Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, 200030, China.
Ding J; Institute of Neurology, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
Bucci C; Department of Biological and Environmental Sciences and Technologies (DiSTeBA), Università del Salento, Via Provinciale Lecce-Monteroni n. 165, 73100, Lecce, Italy. .
Wu C; Department of Neurosciences, University of California San Diego, La Jolla, 92093, CA, USA. .
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Źródło:
Communications biology [Commun Biol] 2022 Jul 18; Vol. 5 (1), pp. 717. Date of Electronic Publication: 2022 Jul 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Charcot-Marie-Tooth Disease*/genetics
rab GTP-Binding Proteins*/genetics
rab GTP-Binding Proteins*/metabolism
Humans ; Laminopathies ; Mitochondria/metabolism ; Sensory Receptor Cells/metabolism ; rab7 GTP-Binding Proteins
SCR Disease Name:
Charcot-Marie-Tooth disease, Type 2B
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Intracellular Distribution of the Small GTPase Rho5 and Its Dimeric Guanidine Nucleotide Exchange Factor Dck1/Lmo1 Determine Their Function in Oxidative Stress Response.
Autorzy:
Bischof L; Department of Genetics, Faculty of Biology/Chemistry, University of Osnabrueck, Barbarastrasse 11, D-49076 Osnabrueck, Germany.
Schweitzer F; Department of Genetics, Faculty of Biology/Chemistry, University of Osnabrueck, Barbarastrasse 11, D-49076 Osnabrueck, Germany.
Sterk CC; Department of Genetics, Faculty of Biology/Chemistry, University of Osnabrueck, Barbarastrasse 11, D-49076 Osnabrueck, Germany.
Heinisch JJ; Department of Genetics, Faculty of Biology/Chemistry, University of Osnabrueck, Barbarastrasse 11, D-49076 Osnabrueck, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 18; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 18.
Typ publikacji:
Journal Article
MeSH Terms:
Monomeric GTP-Binding Proteins*/metabolism
Saccharomyces cerevisiae Proteins*/metabolism
DNA-Binding Proteins/metabolism ; Guanidine ; Guanine Nucleotide Exchange Factors/genetics ; Guanine Nucleotide Exchange Factors/metabolism ; Humans ; LIM Domain Proteins/metabolism ; Mitochondrial Proteins/metabolism ; Nucleotides/metabolism ; Oxidative Stress ; Saccharomyces cerevisiae/metabolism ; Transcription Factors/metabolism ; rho GTP-Binding Proteins/genetics ; rho GTP-Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The RAL Enigma: Distinct Roles of RALA and RALB in Cancer.
Autorzy:
Richardson DS; The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, The Ohio State University, Columbus, OH 43210, USA.
Spehar JM; The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, The Ohio State University, Columbus, OH 43210, USA.
Han DT; The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, The Ohio State University, Columbus, OH 43210, USA.
Chakravarthy PA; The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, The Ohio State University, Columbus, OH 43210, USA.
Sizemore ST; The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, The Ohio State University, Columbus, OH 43210, USA.
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Źródło:
Cells [Cells] 2022 May 14; Vol. 11 (10). Date of Electronic Publication: 2022 May 14.
Typ publikacji:
Journal Article; Review; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Monomeric GTP-Binding Proteins*/metabolism
Neoplasms*
Cell Survival ; GTPase-Activating Proteins/metabolism ; Humans ; ral GTP-Binding Proteins/genetics ; ral GTP-Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Towards Understanding the Development of Breast Cancer: The Role of RhoJ in the Obesity Microenvironment.
Autorzy:
Bou Malhab LJ; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates.
Nair VA; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates.
Qaisar R; Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates.
Pintus G; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Abdel-Rahman WM; Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates.; Department of Medical Laboratory Sciences, College of Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates.
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Źródło:
Cells [Cells] 2024 Jan 17; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/etiology
Breast Neoplasms*/genetics
Obesity*/complications
rho GTP-Binding Proteins*/genetics
rho GTP-Binding Proteins*/metabolism
Animals ; Female ; Humans ; Mice ; Adipokines ; Adiposity ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Function and mechanism of GBP1 in the development and progression of cervical cancer.
Autorzy:
Wang S; Clinical Laboratory Center, Cancer Hospital Affiliated to Xinjiang Medical University, Xinjiang, China.
Zhang Y; Clinical Laboratory Center, Cancer Hospital Affiliated to Xinjiang Medical University, Xinjiang, China.
Ma X; Clinical Laboratory Center, Cancer Hospital Affiliated to Xinjiang Medical University, Xinjiang, China. .
Feng Y; Clinical Laboratory Center, Cancer Hospital Affiliated to Xinjiang Medical University, Xinjiang, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Jan 02; Vol. 22 (1), pp. 11. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
GTP-Binding Proteins*/genetics
GTP-Binding Proteins*/metabolism
Uterine Cervical Neoplasms*/genetics
Female ; Humans ; Cell Line ; Cell Line, Tumor ; Oncogenes ; RNA-Binding Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167.
Autorzy:
Ghilarducci K; Département de Chimie, Université du Québec à Montréal, Montréal, QC H2X 2J6, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois (CERMO-FC), Université du Québec à Montréal, Montréal, QC H2X 3Y7, Canada.
Cabana VC; Département de Chimie, Université du Québec à Montréal, Montréal, QC H2X 2J6, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois (CERMO-FC), Université du Québec à Montréal, Montréal, QC H2X 3Y7, Canada.
Harake A; Département de Chimie, Université du Québec à Montréal, Montréal, QC H2X 2J6, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois (CERMO-FC), Université du Québec à Montréal, Montréal, QC H2X 3Y7, Canada.
Cappadocia L; Département de Chimie, Université du Québec à Montréal, Montréal, QC H2X 2J6, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois (CERMO-FC), Université du Québec à Montréal, Montréal, QC H2X 3Y7, Canada.
Lussier MP; Département de Chimie, Université du Québec à Montréal, Montréal, QC H2X 2J6, Canada.; Centre d'Excellence en Recherche sur les Maladies Orphelines-Fondation Courtois (CERMO-FC), Université du Québec à Montréal, Montréal, QC H2X 3Y7, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 16; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 16.
Typ publikacji:
Journal Article
MeSH Terms:
Charcot-Marie-Tooth Disease*/metabolism
rab GTP-Binding Proteins*/metabolism
Endosomes/metabolism ; HeLa Cells ; Humans ; Lysosomes/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitination ; Ubiquitins/metabolism ; rab7 GTP-Binding Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The G protein alpha chaperone and guanine-nucleotide exchange factor RIC-8 regulates cilia morphogenesis in Caenorhabditis elegans sensory neurons.
Autorzy:
Campagna CM; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, United States of America.
McMahon H; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, United States of America.
Nechipurenko I; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2023 Nov 01; Vol. 19 (11), pp. e1011015. Date of Electronic Publication: 2023 Nov 01 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Caenorhabditis elegans*/growth & development
Caenorhabditis elegans*/metabolism
Caenorhabditis elegans Proteins*/genetics
Caenorhabditis elegans Proteins*/metabolism
Cilia*/genetics
Cilia*/metabolism
Guanine Nucleotide Exchange Factors*/genetics
Guanine Nucleotide Exchange Factors*/metabolism
Heterotrimeric GTP-Binding Proteins*/genetics
Heterotrimeric GTP-Binding Proteins*/metabolism
Morphogenesis*/genetics
Animals ; Humans ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Nucleotides/metabolism ; Sensory Receptor Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A small Rho GTPase OsRacB is required for pollen germination in rice.
Autorzy:
Xu Y; Joint International Research Laboratory of Metabolic and Developmental Sciences, State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Cai W; Joint International Research Laboratory of Metabolic and Developmental Sciences, State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Chen X; Joint International Research Laboratory of Metabolic and Developmental Sciences, State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Chen M; Joint International Research Laboratory of Metabolic and Developmental Sciences, State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Liang W; Joint International Research Laboratory of Metabolic and Developmental Sciences, State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
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Źródło:
Development, growth & differentiation [Dev Growth Differ] 2022 Feb; Vol. 64 (2), pp. 88-97. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji:
Journal Article
MeSH Terms:
Arabidopsis*/genetics
Arabidopsis*/metabolism
Monomeric GTP-Binding Proteins*/metabolism
Oryza*/genetics
Oryza*/metabolism
Plant Proteins/genetics ; Plant Proteins/metabolism ; Pollen/genetics ; Pollen/metabolism ; rho GTP-Binding Proteins/genetics ; rho GTP-Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
AtRAC7/ROP9 Small GTPase Regulates A. thaliana Immune Systems in Response to B. cinerea Infection.
Autorzy:
García-Soto I; Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca 62210, Morelos, Mexico.; Programa de Doctorado en Ciencias Bioquímicas, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca 62210, Morelos, Mexico.
Formey D; Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca 62210, Morelos, Mexico.
Mora-Toledo A; Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca 62210, Morelos, Mexico.; Facultad de Ciencias, Universidad Nacional Autónoma de México, Coyoacan 04510, Ciudad de México, Mexico.
Cárdenas L; Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, Morelos, Mexico.
Aragón W; Instituto de Biociencias, Universidad Autónoma de Chiapas, Blvd. Príncipe Akishino s/n, Tapachula 30798, Chiapas, Mexico.
Tromas A; La Cité College, Bureau de la Recherche et de l'Innovation, Ottawa, ON K1K 4R3, Canada.
Duque-Ortiz A; Instituto Potosino de Investigación Científica y Tecnológica (IPICYT), San Luis Potosí 78216, San Luis Potosí, Mexico.
Jiménez-Bremont JF; Instituto Potosino de Investigación Científica y Tecnológica (IPICYT), San Luis Potosí 78216, San Luis Potosí, Mexico.
Serrano M; Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca 62210, Morelos, Mexico.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 02; Vol. 25 (1). Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Arabidopsis*/genetics
Monomeric GTP-Binding Proteins*/genetics
Actin Cytoskeleton ; Immune System ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 8475

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