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Wyświetlanie 1-20 z 26
Tytuł:
The Kallikrein-Kinin System: A Novel Mediator of IL-17-Driven Anti-Candida Immunity in the Kidney.
Autorzy:
Ramani K; Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Garg AV; Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Jawale CV; Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Conti HR; Department of Biological Sciences, University of Toledo, Toledo, Ohio, United States of America.
Whibley N; Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Jackson EK; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Shiva SS; Vascular Medicine Institute, Dept. of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Horne W; Richard King Mellon Foundation Institute for Pediatric Research, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Kolls JK; Richard King Mellon Foundation Institute for Pediatric Research, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Gaffen SL; Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Biswas PS; Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2016 Nov 04; Vol. 12 (11), pp. e1005952. Date of Electronic Publication: 2016 Nov 04 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Candidiasis/*immunology
Interleukin-17/*immunology
Kallikrein-Kinin System/*immunology
Kidney Diseases/*immunology
Kidney Diseases/*microbiology
Animals ; Blotting, Western ; Disease Models, Animal ; Flow Cytometry ; Immunohistochemistry ; Mice ; Mice, Inbred C57BL ; Oligonucleotide Array Sequence Analysis ; Real-Time Polymerase Chain Reaction
SCR Disease Name:
Systemic candidiasis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
C/EBPβ Promotes Immunity to Oral Candidiasis through Regulation of β-Defensins.
Autorzy:
Simpson-Abelson MR; Division of Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, United States of America.
Childs EE; Division of Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, United States of America.
Ferreira MC; Division of Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, United States of America.
Bishu S; Division of Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, United States of America.
Conti HR; Division of Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, United States of America.
Gaffen SL; Division of Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Aug 28; Vol. 10 (8), pp. e0136538. Date of Electronic Publication: 2015 Aug 28 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
CCAAT-Enhancer-Binding Protein-beta/*immunology
Candida albicans/*immunology
Candidiasis, Oral/*immunology
Gene Expression Regulation/*immunology
beta-Defensins/*immunology
Animals ; CCAAT-Enhancer-Binding Protein-beta/genetics ; Candidiasis, Oral/genetics ; Candidiasis, Oral/pathology ; Interleukin-17/genetics ; Interleukin-17/immunology ; Mice ; Mice, Knockout ; beta-Defensins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Signaling through IL-17C/IL-17RE is dispensable for immunity to systemic, oral and cutaneous candidiasis.
Autorzy:
Conti HR; University of Pittsburgh, Department of Medicine, Division of Rheumatology & Clinical Immunology, Pittsburgh, PA, United States of America.
Whibley N; University of Pittsburgh, Department of Medicine, Division of Rheumatology & Clinical Immunology, Pittsburgh, PA, United States of America.
Coleman BM; University of Pittsburgh, Department of Medicine, Division of Rheumatology & Clinical Immunology, Pittsburgh, PA, United States of America.
Garg AV; University of Pittsburgh, Department of Medicine, Division of Rheumatology & Clinical Immunology, Pittsburgh, PA, United States of America.
Jaycox JR; Carnegie Mellon University, Dept. of Biological Sciences, Pittsburgh, PA, United States of America.
Gaffen SL; University of Pittsburgh, Department of Medicine, Division of Rheumatology & Clinical Immunology, Pittsburgh, PA, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Apr 07; Vol. 10 (4), pp. e0122807. Date of Electronic Publication: 2015 Apr 07 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Candidiasis/*immunology
Candidiasis/*pathology
Interleukin-17/*metabolism
Protein Subunits/*metabolism
Receptors, Interleukin-17/*metabolism
Signal Transduction/*immunology
Animals ; Candidiasis/metabolism ; Candidiasis, Cutaneous/immunology ; Candidiasis, Cutaneous/metabolism ; Candidiasis, Cutaneous/pathology ; Candidiasis, Oral/immunology ; Candidiasis, Oral/metabolism ; Candidiasis, Oral/pathology ; Disease Resistance ; Female ; Interleukin-17/deficiency ; Male ; Mice ; Mice, Inbred C57BL ; Protein Subunits/deficiency ; Receptors, Interleukin-17/deficiency
SCR Disease Name:
Systemic candidiasis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Brothers in arms: Th17 and Treg responses in Candida albicans immunity.
Autorzy:
Whibley N; Division of Rheumatology & Clinical Immunology, Dept. of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Gaffen SL; Division of Rheumatology & Clinical Immunology, Dept. of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2014 Dec 04; Vol. 10 (12), pp. e1004456. Date of Electronic Publication: 2014 Dec 04 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Candida albicans/*immunology
Candidiasis/*immunology
T-Lymphocytes, Regulatory/*immunology
Th17 Cells/*immunology
Animals ; Candidiasis/therapy ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing.
Autorzy:
Gaffen SL; Division of Rheumatology and Clinical Immunology, S702 BST, 3500 Terrace Street, Pittsburgh, Pennsylvania 15261, USA.
Jain R; Merck Research Laboratories, Palo Alto, 901 California Avenue, Palo Alto, California 94304, USA.
Garg AV; Division of Rheumatology and Clinical Immunology, S702 BST, 3500 Terrace Street, Pittsburgh, Pennsylvania 15261, USA.
Cua DJ; Merck Research Laboratories, Palo Alto, 901 California Avenue, Palo Alto, California 94304, USA.
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Źródło:
Nature reviews. Immunology [Nat Rev Immunol] 2014 Sep; Vol. 14 (9), pp. 585-600.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Autoimmune Diseases/*therapy
Interleukin-17/*immunology
Interleukin-23/*immunology
Th17 Cells/*immunology
Antibodies/therapeutic use ; Cytokines/immunology ; Epithelial Cells/immunology ; Humans ; Interleukin-17/genetics ; Interleukin-23/genetics ; Receptors, Interleukin-17/immunology ; Signal Transduction/immunology ; Tight Junctions/immunology ; Transcription, Genetic/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The anaphase-promoting complex protein 5 (AnapC5) associates with A20 and inhibits IL-17-mediated signal transduction.
Autorzy:
Ho AW; Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Garg AV
Monin L
Simpson-Abelson MR
Kinner L
Gaffen SL
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Źródło:
PloS one [PLoS One] 2013 Jul 29; Vol. 8 (7), pp. e70168. Date of Electronic Publication: 2013 Jul 29 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Signal Transduction*
Apc5 Subunit, Anaphase-Promoting Complex-Cyclosome/*metabolism
DNA-Binding Proteins/*metabolism
Interleukin-17/*metabolism
Intracellular Signaling Peptides and Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Amino Acid Motifs ; Animals ; Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome/metabolism ; Carrier Proteins/metabolism ; Cell Line ; Complement Factor D/metabolism ; Cysteine Endopeptidases ; Mice ; Models, Biological ; Protein Binding ; Protein Interaction Mapping ; Protein Subunits/metabolism ; Receptors, Interleukin-17/chemistry ; Receptors, Interleukin-17/metabolism ; Tumor Necrosis Factor alpha-Induced Protein 3 ; Two-Hybrid System Techniques ; ras Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
NADPH oxidase limits innate immune responses in the lungs in mice.
Autorzy:
Segal BH; Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, United States of America. />Han W
Bushey JJ
Joo M
Bhatti Z
Feminella J
Dennis CG
Vethanayagam RR
Yull FE
Capitano M
Wallace PK
Minderman H
Christman JW
Sporn MB
Chan J
Vinh DC
Holland SM
Romani LR
Gaffen SL
Freeman ML
Blackwell TS
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Źródło:
PloS one [PLoS One] 2010 Mar 16; Vol. 5 (3), pp. e9631. Date of Electronic Publication: 2010 Mar 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Enzymologic*
Granulomatous Disease, Chronic/*immunology
Lung/*immunology
NADPH Oxidases/*metabolism
Animals ; Cytokines/metabolism ; Granulomatous Disease, Chronic/enzymology ; Immunity, Innate ; Inflammation ; Lung/metabolism ; Macrophages/metabolism ; Membrane Glycoproteins/genetics ; Mice ; NADPH Oxidase 2 ; NADPH Oxidases/genetics ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/metabolism ; Oxidation-Reduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 26

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