Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Galactosylceramides"" wg kryterium: Temat


Tytuł :
Effects of Glycon and Temperature on Self-Assembly Behaviors of α-Galactosyl Ceramide in Water.
Autorzy :
Miyazaki R; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.
Nargis M; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.
Ihsan AB; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.
Nakajima N; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.; Biotechnology Research Center, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.
Hamada M; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.; Biotechnology Research Center, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.
Koyama Y; Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.; Biotechnology Research Center, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan.
Pokaż więcej
Źródło :
Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2021 Jul 06; Vol. 37 (26), pp. 7936-7944. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Galactosylceramides*
Water*
Hydrophobic and Hydrophilic Interactions ; Micelles ; Temperature
Czasopismo naukowe
Tytuł :
Synthesis and Evaluation of Liposomal Anti-GM3 Cancer Vaccine Candidates Covalently and Noncovalently Adjuvanted by αGalCer.
Autorzy :
Yin XG; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Lu J; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Wang J; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Zhang RY; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Wang XF; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Liao CM; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Liu XP; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Liu Z; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Guo J; Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, P. R. China.
Pokaż więcej
Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Feb 25; Vol. 64 (4), pp. 1951-1965. Date of Electronic Publication: 2021 Feb 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adjuvants, Immunologic/*pharmacology
Cancer Vaccines/*pharmacology
G(M3) Ganglioside/*pharmacology
Galactosylceramides/*pharmacology
Adjuvants, Immunologic/chemical synthesis ; Animals ; Cancer Vaccines/chemical synthesis ; Cancer Vaccines/immunology ; Carbohydrate Sequence ; Female ; G(M3) Ganglioside/analogs & derivatives ; G(M3) Ganglioside/immunology ; Galactosylceramides/chemical synthesis ; Galactosylceramides/immunology ; Humans ; Immunity, Humoral/drug effects ; Immunoglobulin G/immunology ; Liposomes/chemistry ; Mice, Inbred BALB C ; Natural Killer T-Cells/immunology ; THP-1 Cells
Czasopismo naukowe
Tytuł :
The Adjuvant of α-Galactosylceramide Presented by Gold Nanoparticles Enhances Antitumor Immune Responses of MUC1 Antigen-Based Tumor Vaccines.
Autorzy :
Liu Y; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and KLMDASR of Tianjin, Nankai University, Tianjin 300353, People's Republic of China.
Wang Z; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and KLMDASR of Tianjin, Nankai University, Tianjin 300353, People's Republic of China.
Yu F; College of Life Sciences, Nankai University, Tianjin 300071, People's Republic of China.
Li M; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and KLMDASR of Tianjin, Nankai University, Tianjin 300353, People's Republic of China.
Zhu H; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and KLMDASR of Tianjin, Nankai University, Tianjin 300353, People's Republic of China.
Wang K; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and KLMDASR of Tianjin, Nankai University, Tianjin 300353, People's Republic of China.
Meng M; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and KLMDASR of Tianjin, Nankai University, Tianjin 300353, People's Republic of China.
Zhao W; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and KLMDASR of Tianjin, Nankai University, Tianjin 300353, People's Republic of China.
Pokaż więcej
Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Jan 14; Vol. 16, pp. 403-420. Date of Electronic Publication: 2021 Jan 14 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic/*pharmacology
Antigens, Neoplasm/*immunology
Cancer Vaccines/*immunology
Galactosylceramides/*pharmacology
Gold/*pharmacology
Metal Nanoparticles/*chemistry
Mucin-1/*immunology
Adjuvants, Immunologic/administration & dosage ; Animals ; Antibodies, Neoplasm/immunology ; Bone Marrow Cells/drug effects ; Bone Marrow Cells/metabolism ; Cell Line, Tumor ; Cytokines/metabolism ; Cytotoxicity, Immunologic/drug effects ; Dendritic Cells/drug effects ; Dendritic Cells/metabolism ; Female ; Galactosylceramides/chemical synthesis ; Galactosylceramides/chemistry ; Humans ; Immune Sera/metabolism ; Melanoma/immunology ; Melanoma/pathology ; Metal Nanoparticles/ultrastructure ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Spleen/pathology ; T-Lymphocytes, Cytotoxic/drug effects ; T-Lymphocytes, Cytotoxic/immunology
Czasopismo naukowe
Tytuł :
Using agonists for iNKT cells in cancer therapy.
Autorzy :
Painter GF; Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand. Electronic address: .
Burn OK; Malaghan Institute of Medical Research, Wellington, New Zealand.
Hermans IF; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand; Malaghan Institute of Medical Research, Wellington, New Zealand. Electronic address: .
Pokaż więcej
Źródło :
Molecular immunology [Mol Immunol] 2021 Feb; Vol. 130, pp. 1-6. Date of Electronic Publication: 2020 Dec 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Galactosylceramides/*therapeutic use
Immunotherapy/*methods
Lymphocyte Activation/*drug effects
Natural Killer T-Cells/*drug effects
Neoplasms/*therapy
Adjuvants, Immunologic/therapeutic use ; Animals ; Antigen-Presenting Cells/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cancer Vaccines/therapeutic use ; Galactosylceramides/pharmacology ; Humans ; Lymphocyte Activation/physiology ; Natural Killer T-Cells/physiology ; Natural Killer T-Cells/transplantation ; Neoplasms/immunology
Czasopismo naukowe
Tytuł :
Amide-Linked C4″-Saccharide Modification of KRN7000 Provides Potent Stimulation of Human Invariant NKT Cells and Anti-Tumor Immunity in a Humanized Mouse Model.
Autorzy :
Saavedra-Avila NA
Keshipeddy S; Department of Chemistry, The University of Connecticut, Storrs, Connecticut 06269-3060, United States.
Guberman-Pfeffer MJ; Department of Chemistry, The University of Connecticut, Storrs, Connecticut 06269-3060, United States.
Pérez-Gallegos A
Saini NK
Schäfer C; Millennium Institute on Immunology and Immunotherapy, Programa de Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Carreño LJ; Millennium Institute on Immunology and Immunotherapy, Programa de Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Gascón JA; Department of Chemistry, The University of Connecticut, Storrs, Connecticut 06269-3060, United States.
Porcelli SA
Howell AR; Department of Chemistry, The University of Connecticut, Storrs, Connecticut 06269-3060, United States.
Pokaż więcej
Źródło :
ACS chemical biology [ACS Chem Biol] 2020 Dec 18; Vol. 15 (12), pp. 3176-3186. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Amides/*chemistry
Galactosylceramides/*chemistry
Killer Cells, Natural/*drug effects
Neoplasms/*immunology
Sugars/*chemistry
Animals ; Galactosylceramides/pharmacology ; Glycolipids/pharmacology ; Humans ; Killer Cells, Natural/immunology ; Mice ; Models, Animal
Czasopismo naukowe
Tytuł :
Polar functional group-containing glycolipid CD1d ligands modulate cytokine-biasing responses and prevent experimental colitis.
Autorzy :
Inuki S; Graduate School of Science and Technology, Keio University, Hiyoshi, Kohoku-ku, Yokohama, Kanagawa, 223-8522, Japan.; Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, 606-8501, Japan.
Hirata N; Graduate School of Science and Technology, Keio University, Hiyoshi, Kohoku-ku, Yokohama, Kanagawa, 223-8522, Japan.
Kashiwabara E; Graduate School of Science and Technology, Keio University, Hiyoshi, Kohoku-ku, Yokohama, Kanagawa, 223-8522, Japan.
Kishi J; Graduate School of Science and Technology, Keio University, Hiyoshi, Kohoku-ku, Yokohama, Kanagawa, 223-8522, Japan.
Aiba T; Graduate School of Science and Technology, Keio University, Hiyoshi, Kohoku-ku, Yokohama, Kanagawa, 223-8522, Japan.; Department of Chemistry, Graduate School of Science, Osaka University, Machikaneyama-cho, Toyonaka, Osaka, 560-0043, Japan.
Teratani T; School of Medicine, Keio University, Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Nakamura W; Discovery and Research, ONO Pharmaceutical Co., Ltd., Sakurai, Shimamoto, Mishima, Osaka, 618-8585, Japan.
Kojima Y; Discovery and Research, ONO Pharmaceutical Co., Ltd., Sakurai, Shimamoto, Mishima, Osaka, 618-8585, Japan.
Maruyama T; Discovery and Research, ONO Pharmaceutical Co., Ltd., Sakurai, Shimamoto, Mishima, Osaka, 618-8585, Japan.
Kanai T; School of Medicine, Keio University, Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Fujimoto Y; Graduate School of Science and Technology, Keio University, Hiyoshi, Kohoku-ku, Yokohama, Kanagawa, 223-8522, Japan. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2020 Sep 25; Vol. 10 (1), pp. 15766. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD1d/*metabolism
Colitis, Ulcerative/*metabolism
Colitis, Ulcerative/*prevention & control
Cytokines/*metabolism
Galactosylceramides/*chemistry
Galactosylceramides/*pharmacology
Glycolipids/*metabolism
Animals ; Disease Models, Animal ; Drug Design ; Galactosylceramides/metabolism ; Ligands ; Mice ; Solubility ; Structure-Activity Relationship ; Water/chemistry
Czasopismo naukowe
Tytuł :
Two bacterial glycosphingolipid synthases responsible for the synthesis of glucuronosylceramide and α-galactosylceramide.
Autorzy :
Okino N; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan .
Li M; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Qu Q; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Nakagawa T; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Hayashi Y; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Matsumoto M; Electric Power Development Co., Ltd., Wakamatsu Institute, Wakamatsu-ku, Kitakyushu, Fukuoka, Japan.
Ishibashi Y; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Ito M; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.; Innovative Bio-architecture Center, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Nishi-ku, Fukuoka, Japan.
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Jul 31; Vol. 295 (31), pp. 10709-10725. Date of Electronic Publication: 2020 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bacterial Proteins/*metabolism
Galactosylceramides/*biosynthesis
Galactosyltransferases/*metabolism
Glucuronosyltransferase/*metabolism
Glycosphingolipids/*biosynthesis
Zymomonas/*enzymology
Bacterial Proteins/genetics ; Bacteroides fragilis/enzymology ; Bacteroides fragilis/genetics ; Galactosylceramides/genetics ; Galactosyltransferases/genetics ; Glucuronosyltransferase/genetics ; Glycosphingolipids/genetics ; Zymomonas/genetics
Czasopismo naukowe
Tytuł :
Photo effect on the CD1d-binding ability of azobenzene-attached analogues of α-GalCer.
Autorzy :
Kanamori T; School of Life Science and Technology, Tokyo Institute of Technology, 4259 J2-10 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan.
Numata T; School of Life Science and Technology, Tokyo Institute of Technology, 4259 J2-10 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan.
Kuwabara S; School of Life Science and Technology, Tokyo Institute of Technology, 4259 J2-10 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan.
Ishii Y; Department of Immunological Diagnosis, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421 Japan.
Watarai H; Department of Immunology and Stem Cell Biology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan.
Yuasa H; School of Life Science and Technology, Tokyo Institute of Technology, 4259 J2-10 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan. Electronic address: .
Pokaż więcej
Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Mar 01; Vol. 30 (5), pp. 126960. Date of Electronic Publication: 2020 Jan 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD1d/*metabolism
Azo Compounds/*metabolism
Galactosylceramides/*metabolism
Animals ; Antigens, CD1d/chemistry ; Azo Compounds/chemical synthesis ; Azo Compounds/radiation effects ; Galactosylceramides/chemical synthesis ; Galactosylceramides/radiation effects ; Humans ; Mice ; Molecular Docking Simulation ; Natural Killer T-Cells/metabolism ; Protein Binding/radiation effects
Czasopismo naukowe
Tytuł :
Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T- and iNKT Cell Responses.
Autorzy :
Stolk DA; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
de Haas A; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Vree J; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.; Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Duinkerken S; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Lübbers J; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
van de Ven R; Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.; Department of Otolaryngology/Head and Neck Surgery, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Ambrosini M; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Kalay H; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Bruijns S; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
van der Vliet HJ; Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.; LAVA Therapeutics, Utrecht, Netherlands.
de Gruijl TD; Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
van Kooyk Y; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2020 May 27; Vol. 11, pp. 990. Date of Electronic Publication: 2020 May 27 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CD8-Positive T-Lymphocytes/*drug effects
Cancer Vaccines/*pharmacology
Dendritic Cells/*drug effects
Galactosylceramides/*pharmacology
Lewis Blood Group Antigens/*pharmacology
Melanoma/*drug therapy
Natural Killer T-Cells/*drug effects
Peptides/*pharmacology
Skin Neoplasms/*drug therapy
Adaptive Immunity/drug effects ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Cancer Vaccines/immunology ; Cells, Cultured ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Galactosylceramides/immunology ; Humans ; Immunity, Innate/drug effects ; Lewis Blood Group Antigens/immunology ; Liposomes ; Lymphocyte Activation/drug effects ; Melanoma/immunology ; Melanoma/metabolism ; Natural Killer T-Cells/immunology ; Natural Killer T-Cells/metabolism ; Peptides/immunology ; Skin/drug effects ; Skin/immunology ; Skin/metabolism ; Skin Neoplasms/immunology ; Skin Neoplasms/metabolism ; Tissue Culture Techniques
Czasopismo naukowe
Tytuł :
Optical Control of Cytokine Production Using Photoswitchable Galactosylceramides.
Autorzy :
Hartrampf N; Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, USA.
Seki T; The Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, 455 First Avenue, 7th Floor, New York, NY, 10016, USA.; Department of Obstetrics and Gynecology, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo, 105, Japan.
Baumann A; Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, USA.
Watson P; Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, USA.
Vepřek NA; Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, USA.; Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377, München, Germany.
Hetzler BE; Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377, München, Germany.
Hoffmann-Röder A; Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, USA.
Tsuji M; The Aaron Diamond AIDS Research Center, Affiliate of the Rockefeller University, 455 First Avenue, 7th Floor, New York, NY, 10016, USA.
Trauner D; Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, USA.; Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377, München, Germany.
Pokaż więcej
Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Apr 06; Vol. 26 (20), pp. 4476-4479. Date of Electronic Publication: 2020 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD1d/*metabolism
Cytokines/*chemistry
Galactosylceramides/*pharmacology
Glycolipids/*chemistry
Killer Cells, Natural/*drug effects
Antigens, CD1d/chemistry ; Cytokines/metabolism ; Galactosylceramides/chemistry ; Killer Cells, Natural/chemistry ; Natural Killer T-Cells ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Design and Discovery of Covalent α-GalCer Derivatives as Potent CD1d Ligands.
Autorzy :
Kishi J; Faculty of Science and Technology , Keio University , 3-14-1 Hiyoshi , Yokohama , Kanagawa 223-8522 , Japan.
Inuki S; Faculty of Science and Technology , Keio University , 3-14-1 Hiyoshi , Yokohama , Kanagawa 223-8522 , Japan.; Graduate School of Pharmaceutical Sciences , Kyoto University , 46-29 Yoshida-Shimo-Adachi-cho, Sakyo-ku , Kyoto , Kyoto 606-8501 , Japan.
Kashiwabara E; Faculty of Science and Technology , Keio University , 3-14-1 Hiyoshi , Yokohama , Kanagawa 223-8522 , Japan.
Suzuki T; Biomolecular Characterization Unit , RIKEN Center for Sustainable Resource Science , 2-1, Hirosawa , Wako , Saitama 351-0198 Japan.
Dohmae N; Biomolecular Characterization Unit , RIKEN Center for Sustainable Resource Science , 2-1, Hirosawa , Wako , Saitama 351-0198 Japan.
Fujimoto Y; Faculty of Science and Technology , Keio University , 3-14-1 Hiyoshi , Yokohama , Kanagawa 223-8522 , Japan.
Pokaż więcej
Źródło :
ACS chemical biology [ACS Chem Biol] 2020 Feb 21; Vol. 15 (2), pp. 353-359. Date of Electronic Publication: 2020 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD1d/*metabolism
Galactosylceramides/*pharmacology
Acetamides/chemical synthesis ; Acetamides/metabolism ; Acetamides/pharmacology ; Acrylamides/chemical synthesis ; Acrylamides/metabolism ; Acrylamides/pharmacology ; Animals ; Antigens, CD1d/chemistry ; Cysteine/chemistry ; Drug Design ; Drug Discovery ; Galactosylceramides/chemical synthesis ; Galactosylceramides/metabolism ; Interferon-gamma/metabolism ; Interleukin-4/metabolism ; Ligands ; Lymphocyte Activation/drug effects ; Mice ; Molecular Docking Simulation ; Natural Killer T-Cells/drug effects ; Natural Killer T-Cells/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł :
Synthesis and biological activities of amino acids functionalized α-GalCer analogues.
Autorzy :
Ma W; Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China.
Bi J; Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China. Electronic address: .
Zhao C; School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Zhang Z; Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China.
Liu T; Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China.
Zhang G; Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China. Electronic address: .
Pokaż więcej
Źródło :
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Jan 01; Vol. 28 (1), pp. 115141. Date of Electronic Publication: 2019 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adjuvants, Immunologic/*pharmacology
Amino Acids/*pharmacology
Cytokines/*biosynthesis
Galactosylceramides/*pharmacology
Natural Killer T-Cells/*drug effects
Adjuvants, Immunologic/chemical synthesis ; Adjuvants, Immunologic/chemistry ; Amino Acids/chemistry ; Animals ; Cell Proliferation/drug effects ; Cytokines/immunology ; Dose-Response Relationship, Drug ; Female ; Galactosylceramides/chemical synthesis ; Galactosylceramides/chemistry ; Mice ; Mice, Inbred C57BL ; Molecular Structure ; Natural Killer T-Cells/immunology ; Spleen/drug effects ; Spleen/immunology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Galactocerebroside biosynthesis pathways of Mycoplasma species: an antigen triggering Guillain-Barré-Stohl syndrome.
Autorzy :
Gaspari E; Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, the Netherlands.
Koehorst JJ; Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, the Netherlands.
Frey J; Vetsuisse, University of Bern, Bern, Switzerland.
Martins Dos Santos VAP; Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, the Netherlands.; LifeGlimmer GmbH, Berlin, Germany.
Suarez-Diez M; Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, the Netherlands.
Pokaż więcej
Źródło :
Microbial biotechnology [Microb Biotechnol] 2021 May; Vol. 14 (3), pp. 1201-1211. Date of Electronic Publication: 2021 Mar 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Guillain-Barre Syndrome*
Pneumonia, Mycoplasma*
Galactosylceramides ; Glycolipids ; Humans ; Mycoplasma pneumoniae/genetics
Czasopismo naukowe
Tytuł :
Contribution of Invariant Natural Killer T Cells to the Clearance of Pseudomonas aeruginosa from Skin Wounds.
Autorzy :
Tanno H; Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Kanno E; Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Sato S; Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Asao Y; Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Shimono M; Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Kurosaka S; Department of Plastic and Reconstructive Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Oikawa Y; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Ishi S; Department of Plastic and Reconstructive Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Shoji M; Department of Plastic and Reconstructive Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Sato K; Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Kasamatsu J; Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Miyasaka T; Division of Pathophysiology, Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Sendai 981-8558, Japan.
Yamamoto H; Graduate School of Health Sciences, Niigata University, 2-746 Asahimachi-dori, Chuo-ku, Niigata 951-8518, Japan.
Ishii K; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Imai Y; Department of Plastic and Reconstructive Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Tachi M; Department of Plastic and Reconstructive Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Kawakami K; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.; Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 10; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 10.
Typ publikacji :
Journal Article
MeSH Terms :
Natural Killer T-Cells/*immunology
Re-Epithelialization/*genetics
Skin/*immunology
Wound Healing/*genetics
Animals ; Calgranulin B/genetics ; Galactosylceramides/pharmacology ; Gene Expression Regulation/drug effects ; Humans ; Interferon-gamma/genetics ; Interleukin-17/genetics ; Interleukin-23/genetics ; Interleukins/genetics ; Leukocytes/immunology ; Leukocytes/microbiology ; Mice ; Pore Forming Cytotoxic Proteins/pharmacology ; Pseudomonas aeruginosa/genetics ; Pseudomonas aeruginosa/pathogenicity ; Re-Epithelialization/immunology ; Skin/microbiology ; Skin/pathology ; Wound Healing/immunology
Czasopismo naukowe
Tytuł :
Fully Synthetic Invariant NKT Cell-Dependent Self-Adjuvanting Antitumor Vaccines Eliciting Potent Immune Response in Mice.
Autorzy :
Chen PG; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.
Hu HG; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.
Sun ZY; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.
Li QQ; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.
Zhang BD; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.
Wu JJ; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.
Li WH; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.
Zhao YF; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.
Chen YX; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.
Li YM; Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (the Ministry of Education), Department of Chemistry , Tsinghua University , 100084 Beijing , China.; Beijing Institute for Brain Disorders , 100069 Beijing , China.
Pokaż więcej
Źródło :
Molecular pharmaceutics [Mol Pharm] 2020 Feb 03; Vol. 17 (2), pp. 417-425. Date of Electronic Publication: 2019 Dec 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunogenicity, Vaccine*
Adjuvants, Immunologic/*administration & dosage
Cancer Vaccines/*immunology
Galactosylceramides/*administration & dosage
Immunization/*methods
Natural Killer T-Cells/*immunology
Vaccines, Synthetic/*immunology
Adjuvants, Immunologic/chemistry ; Animals ; Antigen-Presenting Cells/immunology ; Antigens, Neoplasm/chemistry ; Antigens, Neoplasm/genetics ; Cancer Vaccines/administration & dosage ; Click Chemistry/methods ; Dendritic Cells/immunology ; Female ; Galactosylceramides/chemistry ; Humans ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; MCF-7 Cells ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mucin-1/chemistry ; Mucin-1/genetics ; Transfection ; Vaccines, Synthetic/administration & dosage
Czasopismo naukowe
Tytuł :
Activation of Invariant Natural Killer T Cell Subsets in C57BL/6J Mice by Different Injection Modes of α-galactosylceramide.
Autorzy :
Meng M; Medical School of Hebei University, Baoding, Hebei Province, China AND Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-autoimmune Diseases in Hebei Province, Baoding, China. .
Chen S; Medical School of Hebei University, Baoding, Hebei Province, China AND Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-autoimmune Diseases in Hebei Province, Baoding, China. .
Gao X; Medical School of Hebei University, Baoding, Hebei Province, China AND Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-autoimmune Diseases in Hebei Province, Baoding, China. .
Liu H; Medical School of Hebei University, Baoding, Hebei Province, China AND Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-autoimmune Diseases in Hebei Province, Baoding, China. .
Zhao H; Medical School of Hebei University, Baoding, Hebei Province, China AND Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-autoimmune Diseases in Hebei Province, Baoding, China. .
Zhang J; Department of Pathology, The First Centre Hospital of Baoding, Baoding, Hebei Province, China. .
Zhang J; Medical School of Hebei University, Baoding, Hebei Province, China AND Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-autoimmune Diseases in Hebei Province, Baoding, China. .
Chen D; Medical School of Hebei University, Baoding, Hebei Province, China AND Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-autoimmune Diseases in Hebei Province, Baoding, China. .
Pokaż więcej
Źródło :
Iranian journal of allergy, asthma, and immunology [Iran J Allergy Asthma Immunol] 2020 Feb 01; Vol. 19 (1), pp. 35-44. Date of Electronic Publication: 2020 Feb 01.
Typ publikacji :
Journal Article
MeSH Terms :
Galactosylceramides/*administration & dosage
Lymphocyte Activation/*drug effects
Natural Killer T-Cells/*drug effects
T-Lymphocyte Subsets/*drug effects
Animals ; Galactosylceramides/immunology ; Injections, Intraperitoneal ; Injections, Subcutaneous ; Liver/drug effects ; Liver/immunology ; Lymphocyte Activation/immunology ; Mice, Inbred C57BL ; Natural Killer T-Cells/immunology ; Spleen/drug effects ; Spleen/immunology ; T-Lymphocyte Subsets/immunology ; Thymus Gland/drug effects ; Thymus Gland/immunology
Czasopismo naukowe
Tytuł :
Structure-Function Implications of the Ability of Monoclonal Antibodies Against α-Galactosylceramide-CD1d Complex to Recognize β-Mannosylceramide Presentation by CD1d.
Autorzy :
Clark K; Vaccine Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Yau J; Vaccine Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Bloom A; Vaccine Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Wang J; Division of Immune Regulation, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Venzon DJ; Biostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Suzuki M; Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute (NHLBI), NIH, Bethesda, MD, United States.
Pasquet L; Vaccine Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Compton BJ; The Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand.
Cardell SL; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Porcelli SA; Department of Microbiology and Immunology and Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, United States.
Painter GF; The Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand.
Zajonc DM; Division of Immune Regulation, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.; Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Berzofsky JA; Vaccine Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Terabe M; Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2019 Oct 09; Vol. 10, pp. 2355. Date of Electronic Publication: 2019 Oct 09 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Galactosylceramides*/chemistry
Galactosylceramides*/immunology
Antibodies, Monoclonal, Murine-Derived/*immunology
Antigen Presentation/*immunology
Antigens, CD1d/*immunology
Natural Killer T-Cells/*immunology
Animals ; Antigens, CD1d/chemistry ; Humans ; Mice ; Mice, Inbred BALB C ; Natural Killer T-Cells/pathology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
3,4-Dideoxy-3,3,4,4-tetrafluoro- and 4-OH epimeric 3-deoxy-3,3-difluoro-α-GalCer analogues: Synthesis and biological evaluation on human iNKT cells stimulation.
Autorzy :
Golten S; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France.
Patinec A; CRCINA, Inserm, Université d'Angers, Université de Nantes, 22 Boulevard Benoni Goullin, 44200, Nantes, France.
Akoumany K; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France.
Rocher J; CRCINA, Inserm, Université d'Angers, Université de Nantes, 22 Boulevard Benoni Goullin, 44200, Nantes, France.
Graton J; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France.
Jacquemin D; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France.
Le Questel JY; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France.
Tessier A; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France.
Lebreton J; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France.
Blot V; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France.
Pipelier M; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France.
Douillard JY; Centre René Gauducheau, Centre Régional de Lutte Contre le Cancer Nantes-Atlantique, 44805, Saint-Herblain Cedex, France.
Le Pendu J; CRCINA, Inserm, Université d'Angers, Université de Nantes, 22 Boulevard Benoni Goullin, 44200, Nantes, France.
Linclau B; School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, United Kingdom.
Dubreuil D; Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2 rue de la Houssinière, BP 92208, 44322, Nantes Cedex 3, France. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2019 Sep 15; Vol. 178, pp. 195-213. Date of Electronic Publication: 2019 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD1d/*metabolism
Galactosylceramides/*pharmacology
Natural Killer T-Cells/*drug effects
Receptors, Antigen, T-Cell/*metabolism
Antigens, CD1d/chemistry ; Galactosylceramides/chemical synthesis ; Galactosylceramides/chemistry ; Galactosylceramides/metabolism ; HeLa Cells ; Humans ; Hydrogen Bonding ; Interferon-gamma/metabolism ; Interleukin-13/metabolism ; Models, Molecular ; Molecular Conformation ; Protein Binding ; Receptors, Antigen, T-Cell/chemistry ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Bacterial immunogenic α-galactosylceramide identified in the murine large intestine: dependency on diet and inflammation.
Autorzy :
von Gerichten J; Lipid Pathobiochemistry Group, Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Heidelberg, Germany.
Lamprecht D; Lipid Pathobiochemistry Group, Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany.
Opálka L; Lipid Pathobiochemistry Group, Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany.; Skin Barrier Research Group, Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Soulard D; Centre d'Infection et d'Immunité de Lille, Inserm U1019, CNRS UMR 8204, University of Lille, CHU Lille, Institut Pasteur de Lille, Lille, France.
Marsching C; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany.
Pilz R; Lipid Pathobiochemistry Group, Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany.; Faculty of Biosciences, University of Heidelberg, Heidelberg, Germany.
Sencio V; Centre d'Infection et d'Immunité de Lille, Inserm U1019, CNRS UMR 8204, University of Lille, CHU Lille, Institut Pasteur de Lille, Lille, France.
Herzer S; Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany.
Galy B; Division of Virus-Associated Carcinogenesis, German Cancer Research Center, Heidelberg, Germany.
Nordström V; Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany.
Hopf C; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany.
Gröne HJ; Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany.; Institute of Pharmacology, University of Marburg, Marburg, Germany.
Trottein F; Centre d'Infection et d'Immunité de Lille, Inserm U1019, CNRS UMR 8204, University of Lille, CHU Lille, Institut Pasteur de Lille, Lille, France.
Sandhoff R; Lipid Pathobiochemistry Group, Department of Cellular and Molecular Pathology, German Cancer Research Center, Heidelberg, Germany .
Pokaż więcej
Źródło :
Journal of lipid research [J Lipid Res] 2019 Nov; Vol. 60 (11), pp. 1892-1904. Date of Electronic Publication: 2019 Sep 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diet*
Bacteroides fragilis/*chemistry
Bacteroides fragilis/*immunology
Galactosylceramides/*immunology
Inflammation/*immunology
Intestine, Large/*immunology
Intestine, Large/*metabolism
Animals ; Galactosylceramides/genetics ; Inflammation/microbiology ; Intestine, Large/microbiology ; Mice ; Mice, Inbred Strains
Czasopismo naukowe
Tytuł :
Towards a surrogate system to express human lipid binding TCRs.
Autorzy :
Wang R; School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.
Pscheid R; School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.
Ghumra A; School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.
Kan LYL; School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.
Cochrane S; Unilever Safety and Environmental Assurance Centre (SEAC), Colworth Science Park, Sharnbrook, MK44 1LQ, UK.
Fairclough L; School of Life Sciences, University of Nottingham, Nottingham, NG7 2RD, UK.
Alcocer MJC; School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK. .
Pokaż więcej
Źródło :
Biotechnology letters [Biotechnol Lett] 2019 Oct; Vol. 41 (10), pp. 1095-1104. Date of Electronic Publication: 2019 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Galactosylceramides/*metabolism
Jurkat Cells/*metabolism
Natural Killer T-Cells/*metabolism
Receptors, Antigen, T-Cell/*metabolism
Animals ; Galactosylceramides/immunology ; Gene Expression ; Humans ; Jurkat Cells/immunology ; Mice ; Natural Killer T-Cells/immunology ; Protein Binding ; Receptors, Antigen, T-Cell/genetics ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies