Autor: "Gandhi, S." - OpacWWW

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Tytuł:: Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death.
Autorzy:: Hughes C; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Choi ML; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Yi JH; Centre for Synaptic Plasticity, Faculty of Health Sciences, University of Bristol, Whitson Street, Bristol, BS1 3NY, UK.; Center for Synaptic Brain Dysfunctions, Institute for Basic Science, Daejeon, 34126, Republic of Korea.
Kim SC; Centre for Synaptic Plasticity, Faculty of Health Sciences, University of Bristol, Whitson Street, Bristol, BS1 3NY, UK.; UK-Dementia Research Institute at King's College London, King's College, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 9NU, UK.
Drews A; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; The German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, Venusberg-Campus, Gebäude 99, 53127, Bonn, Germany.
George-Hyslop PS; Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus The Keith Peters Building Hills Road, Cambridge, CB2 0XY, UK.
Bryant C; Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK.
Gandhi S; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Cho K; Centre for Synaptic Plasticity, Faculty of Health Sciences, University of Bristol, Whitson Street, Bristol, BS1 3NY, UK.; UK-Dementia Research Institute at King's College London, King's College, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 9NU, UK.
Klenerman D; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. .; UK Dementia Research Institute, University of Cambridge, Cambridge, CB2 0XY, UK. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2020 Feb 18; Vol. 3 (1), pp. 79. Date of Electronic Publication: 2020 Feb 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amyloid beta-Peptides/*physiology
Neurons/*physiology
Protein Aggregates/*physiology
Amyloid beta-Peptides/metabolism ; Amyloid beta-Peptides/pharmacology ; Animals ; Animals, Newborn ; Cell Death/drug effects ; Cells, Cultured ; Embryo, Mammalian ; Long-Term Potentiation/drug effects ; Male ; Mice ; Neurons/drug effects ; Protein Aggregation, Pathological/metabolism ; Protein Aggregation, Pathological/physiopathology ; Protein Aggregation, Pathological/psychology ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar ; Signal Transduction/drug effects ; Toll-Like Receptor 4/metabolism

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