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Tytuł :
Exogenous recombinant Hsp70 mediates neuroprotection after photothrombotic stroke.
Autorzy :
Demyanenko S; Laboratory 'Molecular Neurobiology', Academy of Biology and Biotechnology, Southern Federal University, Prospect Stachki 194/1, Rostov-on-Don, 344090, Russia.
Nikul V; Laboratory 'Molecular Neurobiology', Academy of Biology and Biotechnology, Southern Federal University, Prospect Stachki 194/1, Rostov-on-Don, 344090, Russia.
Rodkin S; Laboratory 'Molecular Neurobiology', Academy of Biology and Biotechnology, Southern Federal University, Prospect Stachki 194/1, Rostov-on-Don, 344090, Russia.
Davletshin A; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, 119991, Russia.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, 119991, Russia. .
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, 119991, Russia.
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Źródło :
Cell stress & chaperones [Cell Stress Chaperones] 2021 Jan; Vol. 26 (1), pp. 103-114. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
[Effects of the Hydrogen Sulfide Donor GYY4137 and HSP70 Protein on the Activation of SH-SY5Y Cells by Lipopolysaccharide].
Autorzy :
Yurinskaya MM; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino Scientific Center for Biological Research, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290 Russia.
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.
Afanasiev VN; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino Scientific Center for Biological Research, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290 Russia.
Evgen'ev MB; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino Scientific Center for Biological Research, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290 Russia.; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; .
Vinokurov MG; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino Scientific Center for Biological Research, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290 Russia.
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Źródło :
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2020 Nov-Dec; Vol. 54 (6), pp. 1018-1028.
Typ publikacji :
Journal Article
MeSH Terms :
Hydrogen Sulfide*/pharmacology
HSP70 Heat-Shock Proteins/*metabolism
Morpholines/*pharmacology
Organothiophosphorus Compounds/*pharmacology
Cell Line, Tumor ; Cytokines ; Humans ; Lipopolysaccharides/pharmacology ; Reactive Oxygen Species/metabolism ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
[Exogenous HSP70 and Signaling Pathways Involved in the Inhibition of LPS-Induced Neurotoxicity of Neuroblastoma Cells].
Autorzy :
Yurinskaya MM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow region, 142290 Russia.
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow region, 142290 Russia.; .
Vinokurov MG; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow region, 142290 Russia.
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Źródło :
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2020 Jan-Feb; Vol. 54 (1), pp. 128-136.
Typ publikacji :
Journal Article
MeSH Terms :
Culture Media, Conditioned/*chemistry
HSP70 Heat-Shock Proteins/*pharmacology
Lipopolysaccharides/*toxicity
Neuroblastoma/*drug therapy
Neuroprotection/*drug effects
Neuroprotective Agents/*pharmacology
Signal Transduction/*drug effects
Apoptosis/drug effects ; Culture Media, Conditioned/pharmacology ; Humans ; Lipopolysaccharides/immunology ; Microglia/drug effects ; Microglia/immunology ; Microglia/metabolism ; Neuroblastoma/metabolism ; Neuroblastoma/pathology ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
The molecular chaperone Hsp70 from the thermotolerant Diptera species differs from the Drosophila paralog in its thermostability and higher refolding capacity at extreme temperatures.
Autorzy :
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, Russia, 119991.
Sverchinsky D; Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia, 194064.
Davletshin A; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, Russia, 119991.
Margulis BA; Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia, 194064.
Mitkevich V; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, Russia, 119991.
Kulikov AM; Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia, 119991.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, Russia, 119991. .
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Źródło :
Cell stress & chaperones [Cell Stress Chaperones] 2019 Nov; Vol. 24 (6), pp. 1163-1173. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Species Specificity*
Drosophila melanogaster/*metabolism
HSP70 Heat-Shock Proteins/*chemistry
HSP70 Heat-Shock Proteins/*physiology
Heat-Shock Response/*physiology
Animals ; Cloning, Molecular ; Escherichia coli/genetics ; Hot Temperature ; Thermotolerance/physiology
Czasopismo naukowe
Tytuł :
[The Major Human Stress Protein Hsp70 as a Factor of Protein Homeostasis and a Cytokine-Like Regulator].
Autorzy :
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; .
Zatsepina OG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.
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Źródło :
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2019 Mar-Apr; Vol. 53 (2), pp. 200-217.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Homeostasis*/drug effects
Proteostasis*/drug effects
Cytokines/*metabolism
HSP70 Heat-Shock Proteins/*metabolism
Cytokines/immunology ; Cytokines/pharmacology ; Cytokines/therapeutic use ; HSP70 Heat-Shock Proteins/immunology ; HSP70 Heat-Shock Proteins/pharmacology ; HSP70 Heat-Shock Proteins/therapeutic use ; Humans
Czasopismo naukowe
Tytuł :
Heat shock protein 70 from a thermotolerant Diptera species provides higher thermoresistance to Drosophila larvae than correspondent endogenous gene.
Autorzy :
Shilova VY; Engelhardt Institute of Molecular Biology, RAS, Moscow, Russia.; Institute of Cell Biophysics, RAS, Pushchino, Moscow, Russia.
Zatsepina OG; Engelhardt Institute of Molecular Biology, RAS, Moscow, Russia.
Garbuz DG; Engelhardt Institute of Molecular Biology, RAS, Moscow, Russia.
Funikov SY; Engelhardt Institute of Molecular Biology, RAS, Moscow, Russia.
Zelentsova ES; Engelhardt Institute of Molecular Biology, RAS, Moscow, Russia.
Schostak NG; Engelhardt Institute of Molecular Biology, RAS, Moscow, Russia.
Kulikov AM; Institute of Developmental Biology, RAS, Moscow, Russia.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, RAS, Moscow, Russia.; Institute of Cell Biophysics, RAS, Pushchino, Moscow, Russia.
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Źródło :
Insect molecular biology [Insect Mol Biol] 2018 Feb; Vol. 27 (1), pp. 61-72. Date of Electronic Publication: 2017 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heat-Shock Response*
Thermotolerance*
Diptera/*physiology
HSP70 Heat-Shock Proteins/*genetics
Insect Proteins/*genetics
Animals ; Diptera/genetics ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/genetics ; Drosophila melanogaster/growth & development ; Drosophila melanogaster/physiology ; HSP70 Heat-Shock Proteins/metabolism ; Insect Proteins/metabolism ; Larva/genetics ; Larva/growth & development ; Larva/physiology ; Longevity ; Promoter Regions, Genetic ; Species Specificity
Czasopismo naukowe
Tytuł :
Interplay between recombinant Hsp70 and proteasomes: proteasome activity modulation and ubiquitin-independent cleavage of Hsp70.
Autorzy :
Morozov AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, 119991, Russia. .
Astakhova TM; Koltzov Institute of Developmental Biology, Russian Academy of Sciences, Vavilov str. 26, Moscow, 124319, Russia.
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, 119991, Russia.
Krasnov GS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, 119991, Russia.
Bobkova NV; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Institutskaya st. 3, Pushchino, Moscow Region, 142290, Russia.
Zatsepina OG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, 119991, Russia.
Karpov VL; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, 119991, Russia.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov str. 32, Moscow, 119991, Russia.
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Źródło :
Cell stress & chaperones [Cell Stress Chaperones] 2017 Sep; Vol. 22 (5), pp. 687-697. Date of Electronic Publication: 2017 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
HSP70 Heat-Shock Proteins/*metabolism
Proteasome Endopeptidase Complex/*metabolism
Ubiquitin/*metabolism
Cell Line ; Electrophoresis, Polyacrylamide Gel ; HSP70 Heat-Shock Proteins/genetics ; Humans ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Czasopismo naukowe
Tytuł :
[Regulation of heat shock gene expression in response to stress].
Autorzy :
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.; .
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Źródło :
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2017 May-Jun; Vol. 51 (3), pp. 400-417.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Transcription, Genetic*
Heat-Shock Proteins/*genetics
Heat-Shock Response/*genetics
Transcriptional Activation/*genetics
Animals ; DNA-Binding Proteins/genetics ; Drosophila Proteins/genetics ; Drosophila melanogaster/genetics ; Gene Expression Regulation, Plant ; HSP70 Heat-Shock Proteins/genetics ; Heat Shock Transcription Factors ; Heat-Shock Proteins/biosynthesis ; Hot Temperature ; Membrane Proteins/genetics ; Sumoylation/genetics ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
[The evolution of heat shock genes and expression patterns of heat shock proteins in the species from temperature contrasting habitats].
Autorzy :
Garbuz DG
Evgen’ev MB
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Źródło :
Genetika [Genetika] 2017 Jan; Vol. 53 (1), pp. 12-30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Ecosystem*
Evolution, Molecular*
Heat-Shock Proteins*/biosynthesis
Heat-Shock Proteins*/genetics
Hot Temperature*
Phylogeny*
Gene Expression Regulation/*physiology
Czasopismo naukowe
Tytuł :
Molecular Mechanisms Underlying Neuroprotective Effect of Intranasal Administration of Human Hsp70 in Mouse Model of Alzheimer's Disease.
Autorzy :
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Moscow, Russia.; Institute of Cell Biophysics, RAS, Pushchino, Moscow region, Russia.
Krasnov GS; Engelhardt Institute of Molecular Biology, Moscow, Russia.
Nesterova IV; Institute of Cell Biophysics, RAS, Pushchino, Moscow region, Russia.
Garbuz DG; Engelhardt Institute of Molecular Biology, Moscow, Russia.
Karpov VL; Engelhardt Institute of Molecular Biology, Moscow, Russia.
Morozov AV; Engelhardt Institute of Molecular Biology, Moscow, Russia.
Snezhkina AV; Engelhardt Institute of Molecular Biology, Moscow, Russia.
Samokhin AN; Institute of Cell Biophysics, RAS, Pushchino, Moscow region, Russia.
Sergeev A; Institute of Cell Biophysics, RAS, Pushchino, Moscow region, Russia.
Kulikov AM; Institute of Developmental Biology, Moscow, Russia.
Bobkova NV; Institute of Cell Biophysics, RAS, Pushchino, Moscow region, Russia.
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Źródło :
Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2017; Vol. 59 (4), pp. 1415-1426.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease/*drug therapy
Gene Expression Regulation/*drug effects
HSP70 Heat-Shock Proteins/*administration & dosage
Neuroprostanes/*administration & dosage
Administration, Intranasal/methods ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Amyloid beta-Protein Precursor/genetics ; Analysis of Variance ; Animals ; Brain/pathology ; Disease Models, Animal ; Gene Expression Regulation/genetics ; Humans ; Male ; Mice ; Mice, Transgenic ; Mutation/genetics ; Neurons/drug effects ; Presenilin-1/genetics
Czasopismo naukowe
Tytuł :
[Heat-shock protein HSP70 decreases activity of proteasomes in human neuroblastoma cells treated by amyloid-beta 1-42 with isomerized Asp7].
Autorzy :
Morozov AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; .
Yurinskaya MM; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290 Russia.
Mitkevich VA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Preobrazhenskaia OV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Vinokurov MG; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290 Russia.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Karpov VL; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Makarov AA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
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Źródło :
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2017 Jan-Feb; Vol. 51 (1), pp. 166-171.
Typ publikacji :
Journal Article
MeSH Terms :
Neuroblastoma*
HSP70 Heat-Shock Proteins/*pharmacology
Proteasome Endopeptidase Complex/*metabolism
Alzheimer Disease ; Amyloid beta-Peptides ; Animals ; Cell Line, Tumor ; Humans ; Mice ; Peptide Fragments
Czasopismo naukowe
Tytuł :
The development of modified human Hsp70 (HSPA1A) and its production in the milk of transgenic mice.
Autorzy :
Gurskiy YG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.; Institute of Experimental Cardiology, Cardiology Research Center, Moscow, 125552, Russia.
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Soshnikova NV; Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
Krasnov AN; Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
Deikin A; Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
Lazarev VF; Institute of Cytology, Russian Academy of Sciences, 194064, St. Petersburg, Russia.
Sverchinskyi D; Institute of Cytology, Russian Academy of Sciences, 194064, St. Petersburg, Russia.
Margulis BA; Institute of Cytology, Russian Academy of Sciences, 194064, St. Petersburg, Russia.
Zatsepina OG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Karpov VL; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Belzhelarskaya SN; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Feoktistova E; Institute of Experimental Cardiology, Cardiology Research Center, Moscow, 125552, Russia.
Georgieva SG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.; Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia. .; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow, Russia. .
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Źródło :
Cell stress & chaperones [Cell Stress Chaperones] 2016 Nov; Vol. 21 (6), pp. 1055-1064. Date of Electronic Publication: 2016 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
HSP70 Heat-Shock Proteins/*metabolism
Milk/*metabolism
Animals ; Female ; HSP70 Heat-Shock Proteins/genetics ; Humans ; Lipopolysaccharides/toxicity ; Male ; Mice ; Mice, Inbred C3H ; Mice, Transgenic ; Mutagenesis, Site-Directed ; Neutrophils/cytology ; Neutrophils/drug effects ; Neutrophils/metabolism ; Protein Refolding ; Reactive Oxygen Species/metabolism ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Interplay between RNA interference and heat shock response systems in Drosophila melanogaster.
Autorzy :
Funikov SY; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russian Federation.
Ryazansky SS; Institute of Molecular Genetics, Russian Academy of Sciences, Moscow 123182, Russian Federation.
Kanapin AA; University of Oxford, Oxford, UK.
Logacheva MD; Lomonosov Moscow State University, Moscow 119991, Russian Federation.
Penin AA; Lomonosov Moscow State University, Moscow 119991, Russian Federation.; Institute for Information Transmission Problems of the Russian Academy of Sciences, Moscow 127051, Russian Federation.
Snezhkina AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russian Federation.
Shilova VY; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russian Federation.
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russian Federation.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russian Federation .
Zatsepina OG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russian Federation.
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Źródło :
Open biology [Open Biol] 2016 Oct; Vol. 6 (10).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heat-Shock Response*
Drosophila melanogaster/*genetics
High-Throughput Nucleotide Sequencing/*methods
MicroRNAs/*genetics
Sequence Analysis, RNA/*methods
Animals ; Drosophila Proteins ; Drosophila melanogaster/classification ; Gene Deletion ; Gene Expression Regulation ; HSP70 Heat-Shock Proteins/genetics ; RNA Interference
Czasopismo naukowe
Tytuł :
A Drosophila heat shock response represents an exception rather than a rule amongst Diptera species.
Autorzy :
Zatsepina OG; Engelgardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Przhiboro AA; Zoological Institute, Russian Academy of Sciences, St. Petersburg, Russia.; Tyumen State University, Tyumen, Russia.
Yushenova IA; Engelgardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Shilova V; Engelgardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Zelentsova ES; Engelgardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Shostak NG; Engelgardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Evgen'ev MB; Engelgardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Garbuz DG; Engelgardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
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Źródło :
Insect molecular biology [Insect Mol Biol] 2016 Aug; Vol. 25 (4), pp. 431-49. Date of Electronic Publication: 2016 Apr 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heat-Shock Response*
Diptera/*physiology
HSP70 Heat-Shock Proteins/*genetics
Animals ; Biological Evolution ; Diptera/genetics ; Diptera/growth & development ; Drosophila melanogaster/genetics ; Drosophila melanogaster/growth & development ; Drosophila melanogaster/physiology ; HSP70 Heat-Shock Proteins/metabolism ; Larva/genetics ; Larva/growth & development ; Larva/physiology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Species Specificity
Czasopismo naukowe

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