Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates.
Autorzy :
García-Huerta P; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Sector B, Second Floor, Faculty of Medicine, University of Chile, Independencia 1027, P.O. Box 70086, Santiago, Chile. Troncoso-Escudero P; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Sector B, Second Floor, Faculty of Medicine, University of Chile, Independencia 1027, P.O. Box 70086, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile. Wu D; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Thiruvalluvan A; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Cisternas-Olmedo M; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile. Henríquez DR; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Department of Cell Biology, Faculty of Sciences, University of Chile, Santiago, Chile. Plate L; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA. Chana-Cuevas P; Faculty of Medical Sciences, University of Santiago de Chile, Santiago, Chile. Saquel C; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile. Thielen P; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, 02115, USA. Longo KA; Proteostasis Therapeutics, Cambridge, MA, USA. GeddesBJ; Proteostasis Therapeutics, Cambridge, MA, USA. Lederkremer GZ; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel. Sharma N; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel. Shenkman M; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel. Naphade S; Buck Institute for Research on Aging, Novato, CA, 94945, USA. Sardi SP; Rare and Neurological Diseases Therapeutic Area, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA. Spichiger C; Faculty of Sciences, Institute of Biochemistry and Microbiology, University Austral of Chile, Valdivia, Chile. Richter HG; Faculty of Medicine, Institute of Anatomy, Histology and Pathology, University Austral of Chile, Valdivia, Chile. Court FA; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile.; Buck Institute for Research on Aging, Novato, CA, 94945, USA. Tshilenge KT; Buck Institute for Research on Aging, Novato, CA, 94945, USA. Ellerby LM; Buck Institute for Research on Aging, Novato, CA, 94945, USA. Wiseman RL; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA. Gonzalez-Billault C; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Department of Cell Biology, Faculty of Sciences, University of Chile, Santiago, Chile.; Buck Institute for Research on Aging, Novato, CA, 94945, USA. Bergink S; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Vidal RL; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile. .; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile. .; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile. . Hetz C; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile. .; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile. .; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Sector B, Second Floor, Faculty of Medicine, University of Chile, Independencia 1027, P.O. Box 70086, Santiago, Chile. .; Buck Institute for Research on Aging, Novato, CA, 94945, USA. .
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Źródło :
Acta neuropathologica [Acta Neuropathol] 2020 Nov; Vol. 140 (5), pp. 737-764. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Defining preoperative imaging findings of sacral chordomas associated with decreased overall survival and local recurrence.
Autorzy :
Munger AM; Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA. GeddesBJ; Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA. Lee FY; Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
General Health Adverse Events Within 30 Days Following Anterior Cervical Discectomy and Fusion in US Patients: A Comparison of Spine Surgeons' Perceptions and Reported Data for Rates and Risk Factors.
Autorzy :
Ondeck NT; Yale School of Medicine, New Haven, CT, USA. Bohl DD; Rush University Medical Center, Chicago, IL, USA. Bovonratwet P; Yale School of Medicine, New Haven, CT, USA. GeddesBJ; Yale School of Medicine, New Haven, CT, USA. Cui JJ; Yale School of Medicine, New Haven, CT, USA. McLynn RP; Yale School of Medicine, New Haven, CT, USA. Samuel AM; Hospital for Special Surgery, New York, NY, USA. Grauer JN; Yale School of Medicine, New Haven, CT, USA.
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Źródło :
Global spine journal [Global Spine J] 2018 Jun; Vol. 8 (4), pp. 345-353. Date of Electronic Publication: 2017 Sep 14.
Inaccuracies in ICD Coding for Obesity Would Be Expected to Bias Administrative Database Spine Studies Toward Overestimating the Impact of Obesity on Perioperative Adverse Outcomes.
Comparison of 30-Day Complications Between Navigated and Conventional Single-level Instrumented Posterior Lumbar Fusion: A Propensity Score Matched Analysis.
Use of a Novel Pathway for Early Discharge Was Associated With a 48% Shorter Length of Stay After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.
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