- Tytuł:
- mTOR inhibition improves fibroblast growth factor receptor targeting in hepatocellular carcinoma.
- Autorzy:
- Źródło:
- British journal of cancer [Br J Cancer] 2015 Mar 03; Vol. 112 (5), pp. 841-50. Date of Electronic Publication: 2015 Feb 17.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Carcinoma, Hepatocellular/*drug therapy
Liver Neoplasms/*drug therapy
Phenylurea Compounds/*pharmacology
Pyrimidines/*pharmacology
Receptor, Fibroblast Growth Factor, Type 1/*antagonists & inhibitorsSirolimus /*pharmacology
TOR Serine-Threonine Kinases/*antagonists & inhibitors
Animals ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Drug Synergism ; Gene Expression Regulation, Neoplastic/drug effects ; Hep G2 Cells ; Humans ; Liver Neoplasms/pathology ; Mice ; Mice, Nude ; Neoplasm Transplantation ; Phenylurea Compounds/administration & dosage ; Pyrimidines/administration & dosage ; Signal Transduction/drug effects ;Sirolimus /administration & dosage ; Xenograft Model Antitumor Assays
Czasopismo naukowe