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Tytuł:
Azacitidine–venetoclax versus azacitidine salvage treatment for primary induction failure or first relapsed acute myeloid leukaemia patients.
Autorzy:
Petit, C.
Saillard, C.
Mohty, B.
Hicheri, Y.
Villetard, F.
Maisano, V.
Charbonnier, A.
Rey, J.
D'Incan, E.
Rouzaud, C.
GelsiBoyer, V.
Murati, A.
Lhoumeau, A. C.
Ittel, A.
Mozziconacci, M. J.
Alary, A. S.
Hospital, M.‐A.
Vey, N.
Garciaz, S.
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Temat:
ACUTE myeloid leukemia
AZACITIDINE
STEM cell transplantation
DISEASE relapse
SURVIVAL rate
Źródło:
European Journal of Haematology; Apr2024, Vol. 112 Issue 4, p530-537, 8p
Czasopismo naukowe
Tytuł:
Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML)
Autorzy:
Coppin, EAff1, Aff2, Aff3, Aff4
Gelsi-Boyer, VAff1, Aff2, Aff3, Aff4
Morelli, XAff1, Aff2, Aff3, Aff4
Cervera, NAff1, Aff2, Aff3, Aff4
Murati, AAff1, Aff2, Aff3, Aff4
Pandolfi, P PAff5, Aff6, Aff7
Birnbaum, DAff1, Aff2, Aff3, Aff4
Nunès, J AAff1, Aff2, Aff3, Aff4, IDleu2014288_cor8
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Źródło:
Leukemia. 29(2):500-502
Czasopismo naukowe
Tytuł:
SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias
Autorzy:
Damm, FAff1, Aff2, Aff3
Itzykson, RAff1, Aff2, Aff4
Kosmider, OAff5, Aff6, Aff7
Droin, NAff1, Aff2, Aff4
Renneville, A
Chesnais, VAff5, Aff6, Aff7
Gelsi-Boyer, VAff9, Aff10, Aff11
de Botton, SAff1, Aff2, Aff3, Aff12
Vey, NAff9, Aff11, Aff13
Preudhomme, CAff8, Aff14, Aff15
Clavert, A
Delabesse, E
Park, S
Birnbaum, DAff9, Aff10, Aff11
Fontenay, MAff5, Aff6, Aff7
Bernard, O AAff1, Aff2, Aff3
Solary, EAff1, Aff2, Aff4, Aff9, IDleu201335_cor17
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Źródło:
Leukemia. 27(6):1401-1403
Czasopismo naukowe
Tytuł:
Gene expression profiling separates chronic myelomonocytic leukemia in two molecular subtypes
Autorzy:
Gelsi-Boyer, VAff1, Aff7, Aff5, Aff2, Aff3
Cervera, NAff1, Aff7, Aff5
Bertucci, FAff1, Aff7, Aff5, Aff3
Trouplin, VAff1, Aff7, Aff5, Aff2
Remy, VAff1, Aff7, Aff5
Olschwang, SAff1, Aff7, Aff5
Chaffanet, MAff1, Aff7, Aff5
Vey, N
Mozziconacci, M-JAff1, Aff7, Aff5, Aff2
Birnbaum, DAff1, Aff7, Aff5, ID2404805_cor10
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Źródło:
Leukemia. 21(11):2359-2362
Czasopismo naukowe
Tytuł:
PCM1-JAK2 fusion in myeloproliferative disorders and acute erythroid leukemia with t(8;9) translocation
Autorzy:
Murati, AAff1, Aff2
Gelsi-Boyer, VAff1, Aff2, Aff3
Adélaïde, J
Perot, C
Talmant, P
Giraudier, S
Lodé, L
Letessier, A
Delaval, B
Brunel, V
Imbert, M
Garand, R
Xerri, LAff2, Aff3
Birnbaum, D
Mozziconacci, M JAff1, Aff2, ID2403879_cor15
Chaffanet, M
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Źródło:
Leukemia. 19(9):1692-1696
Czasopismo naukowe
Tytuł:
Azacitidine Plus Venetoclax for the Treatment of Relapsed and Newly Diagnosed Acute Myeloid Leukemia Patients.
Autorzy:
Garciaz S; INSERM, CNRS, Department of Hematology, Institut Paoli-Calmettes, Aix-Marseille University, 13009 Marseille, France.; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Hospital MA; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Alary AS; Department of Molecular Biology, Institut Paoli-Calmettes, 13009 Marseille, France.
Saillard C; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Hicheri Y; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Mohty B; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Rey J; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
D'Incan E; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Charbonnier A; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Villetard F; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Maisano V; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Lombardi L; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
Ittel A; Department of Biopathology, Institut Paoli-Calmettes, 13009 Marseille, France.
Mozziconacci MJ; Department of Biopathology, Institut Paoli-Calmettes, 13009 Marseille, France.
Gelsi-Boyer V; Department of Biopathology, Institut Paoli-Calmettes, 13009 Marseille, France.; Predictive Laboratory Oncology, Equipe Labellisée Ligue Contre le Cancer, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR 1068, CNRS UMR725, Aix-Marseille Université, 13007 Marseille, France.
Vey N; INSERM, CNRS, Department of Hematology, Institut Paoli-Calmettes, Aix-Marseille University, 13009 Marseille, France.; Deparment of Hematology, Institut Paoli-Calmettes, 13009 Marseille, France.
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Źródło:
Cancers [Cancers (Basel)] 2022 Apr 16; Vol. 14 (8). Date of Electronic Publication: 2022 Apr 16.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms
Autorzy:
Kosmider, OAff1, Aff2, Aff3, Aff4, Aff5
Gelsi-Boyer, V
Slama, LAff1, Aff2, Aff3, Aff4
Dreyfus, FAff2, Aff3, Aff4, Aff5, Aff7
Beyne-Rauzy, O
Quesnel, B
Hunault-Berger, M
Slama, B
Vey, N
Lacombe, CAff1, Aff2, Aff3, Aff4, Aff5
Solary, E
Birnbaum, D
Bernard, O AAff1, Aff14
Fontenay, MAff1, Aff2, Aff3, Aff4, Aff5, IDleu201052_cor14
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Źródło:
Leukemia. 24(5):1094-1096
Czasopismo naukowe
Tytuł:
Mutation patterns in essential thrombocythemia, polycythemia vera and secondary myelofibrosis.
Autorzy:
Wanquet A; a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.; b Aix-Marseille Université , Marseille , France.; c Département d'Hématologie , Institut Paoli-Calmettes , Marseille , France.
Courtier F; a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.; b Aix-Marseille Université , Marseille , France.
Guille A; a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.
Carbuccia N; a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.
Garnier S; a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.
Adélaide J; a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.
Gelsi-Boyer V; a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.; b Aix-Marseille Université , Marseille , France.; d Département de BioPathologie , Institut Paoli-Calmettes , Marseille , France.
Mozziconacci MJ; d Département de BioPathologie , Institut Paoli-Calmettes , Marseille , France.
Rey J; c Département d'Hématologie , Institut Paoli-Calmettes , Marseille , France.
Vey N; b Aix-Marseille Université , Marseille , France.; c Département d'Hématologie , Institut Paoli-Calmettes , Marseille , France.
Birnbaum D; a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.; b Aix-Marseille Université , Marseille , France.
Murati A; a Laboratoire d'Oncologie Prédictive , Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille , Inserm U1068 CNRS UMR 7258 , Marseille , France.; b Aix-Marseille Université , Marseille , France.; d Département de BioPathologie , Institut Paoli-Calmettes , Marseille , France.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2019 May; Vol. 60 (5), pp. 1289-1293. Date of Electronic Publication: 2019 Jan 02.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Predisposition to Disease*
Mutation*
Polycythemia Vera/*genetics
Primary Myelofibrosis/*genetics
Thrombocythemia, Essential/*genetics
Biomarkers ; Genetic Association Studies ; Humans ; Kaplan-Meier Estimate ; Polycythemia Vera/diagnosis ; Polycythemia Vera/mortality ; Primary Myelofibrosis/diagnosis ; Primary Myelofibrosis/mortality ; Prognosis ; Thrombocythemia, Essential/diagnosis ; Thrombocythemia, Essential/mortality
Raport
Tytuł:
Assessment of 2022 European LeukemiaNet risk classification system in real‐world cohort from China.
Autorzy:
Chen, Enbo (AUTHOR)
Jiao, Changqing (AUTHOR)
Yu, Jian (AUTHOR)
Gong, Yu (AUTHOR)
Jin, Duo (AUTHOR)
Ma, Xiaoyu (AUTHOR)
Cui, Jianling (AUTHOR)
Wu, Zhonghui (AUTHOR)
Zhou, Junjie (AUTHOR)
Wang, Haixia (AUTHOR)
Su, Bobing (AUTHOR)
Ge, Jian (AUTHOR)
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Źródło:
Cancer Medicine. Dec2023, Vol. 12 Issue 24, p21615-21626. 12p.
Czasopismo naukowe
Tytuł:
Discovery of novel enasidenib analogues targeting inhibition of mutant isocitrate dehydrogenase 2 as antileukaemic agents.
Autorzy:
Khalil, Ahmed F. (AUTHOR)
El-Moselhy, Tarek F. (AUTHOR)
El-Bastawissy, Eman A. (AUTHOR)
Abdelhady, Rasha (AUTHOR)
Younis, Nancy S. (AUTHOR)
El-Hamamsy, Mervat H. (AUTHOR)
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Źródło:
Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-22. 22p.
Czasopismo naukowe
Tytuł:
Alterations of the expression of TET2 and DNA 5-hmC predict poor prognosis in Myelodysplastic Neoplasms.
Autorzy:
Seethy, Ashikh A. (AUTHOR)
Pethusamy, Karthikeyan (AUTHOR)
Kushwaha, Tushar (AUTHOR)
Kumar, Gaurav (AUTHOR)
Talukdar, Joyeeta (AUTHOR)
Chaubey, Rekha (AUTHOR)
Sundaram, Udayakumar Dharmalingam (AUTHOR)
Mahapatra, Manoranjan (AUTHOR)
Saxena, Renu (AUTHOR)
Dhar, Ruby (AUTHOR)
Inampudi, Krishna K. (AUTHOR)
Karmakar, Subhradip (AUTHOR)
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Źródło:
BMC Cancer. 10/26/2023, Vol. 23 Issue 1, p1-18. 18p.
Czasopismo naukowe
Tytuł:
Chromosome‐level Asian elephant genome assembly and comparative genomics of long‐lived mammals reveal the common substitutions for cancer resistance.
Autorzy:
Li, Xuanjing (AUTHOR)
Wang, Pengcheng (AUTHOR)
Pan, Qi (AUTHOR)
Liu, Gaoming (AUTHOR)
Liu, Weiqiang (AUTHOR)
Omotoso, Olatunde (AUTHOR)
Du, Juan (AUTHOR)
Li, Zihao (AUTHOR)
Yu, Yang (AUTHOR)
Huang, Yun (AUTHOR)
Zhu, Pingfen (AUTHOR)
Li, Meng (AUTHOR)
Zhou, Xuming (AUTHOR)
Pokaż więcej
Źródło:
Aging Cell. Sep2023, Vol. 22 Issue 9, p1-16. 16p.
Czasopismo naukowe
Tytuł:
YY1 Knockdown Relieves the Differentiation Block and Restores Apoptosis in AML Cells.
Autorzy:
Noguera, Nelida Ines (AUTHOR)
Travaglini, Serena (AUTHOR)
Scalea, Stefania (AUTHOR)
Catalanotto, Caterina (AUTHOR)
Reale, Anna (AUTHOR)
Zampieri, Michele (AUTHOR)
Zaza, Alessandra (AUTHOR)
Ricciardi, Maria Rosaria (AUTHOR)
Angelini, Daniela Francesca (AUTHOR)
Tafuri, Agostino (AUTHOR)
Ottone, Tiziana (AUTHOR)
Voso, Maria Teresa (AUTHOR)
Zardo, Giuseppe (AUTHOR)
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Źródło:
Cancers. Aug2023, Vol. 15 Issue 15, p4010. 22p.
Czasopismo naukowe
Tytuł:
59 Myelodysplastic syndromes with isolated neutropenia or thrombocytopenia: Are they refractory cytopenias with unilineage dysplasia? A GFM registry study
Autorzy:
Gyan, E.
Andrieu, V.
Caille, A.
Park, S.
Stamatoullas, A.
Sélosse, V.
Bordessoule, D.
Gelsi-Boyer, V.
Ades, L.
Vey, N.
Cheze, S.
Beyne-Rauzy, O.
Sapena, R.
Zerazhi, H.
Legros, L.
Guerci-Bresler, A.
Fenaux, P.
Dreyfus, F.
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Źródło:
In Leukemia Research 2011 35 Supplement 1:S22-S22
Czasopismo naukowe
Tytuł:
ZNF703 mRNA-Targeting Antisense Oligonucleotide Blocks Cell Proliferation and Induces Apoptosis in Breast Cancer Cell Lines.
Autorzy:
Udu-Ituma, Sandra (AUTHOR)
Adélaïde, José (AUTHOR)
Le, Thi Khanh (AUTHOR)
Omabe, Kenneth (AUTHOR)
Finetti, Pascal (AUTHOR)
Paris, Clément (AUTHOR)
Guille, Arnaud (AUTHOR)
Bertucci, François (AUTHOR)
Birnbaum, Daniel (AUTHOR)
Rocchi, Palma (AUTHOR)
Chaffanet, Max (AUTHOR)
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Źródło:
Pharmaceutics. Jul2023, Vol. 15 Issue 7, p1930. 17p.
Czasopismo naukowe
Tytuł:
Extreme Gradient Boosting Tuned with Metaheuristic Algorithms for Predicting Myeloid NGS Onco-Somatic Variant Pathogenicity.
Autorzy:
Pellegrino, Eric (AUTHOR)
Camilla, Clara (AUTHOR)
Abbou, Norman (AUTHOR)
Beaufils, Nathalie (AUTHOR)
Pissier, Christel (AUTHOR)
Gabert, Jean (AUTHOR)
Nanni-Metellus, Isabelle (AUTHOR)
Ouafik, L'Houcine (AUTHOR)
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Źródło:
Bioengineering (Basel). Jul2023, Vol. 10 Issue 7, p753. 38p.
Czasopismo naukowe
Tytuł:
Clinical characteristics and prognosis analysis of patients with de novo ASXL1‐mutated AML treated with the C‐HUNAN‐AML‐15 protocol: A multicenter study by the South China Pediatric AML Collaborative Group.
Autorzy:
Zeng, Minhui (AUTHOR)
Chen, Keke (AUTHOR)
Tian, Xin (AUTHOR)
Zou, Runying (AUTHOR)
Feng, Xiaoqin (AUTHOR)
Li, Chunfu (AUTHOR)
Li, Jian (AUTHOR)
Zheng, Mincui (AUTHOR)
Mai, Huirong (AUTHOR)
Yang, Lihua (AUTHOR)
He, Yingyi (AUTHOR)
Xu, Honggui (AUTHOR)
Wen, Hong (AUTHOR)
He, Xiangling (AUTHOR)
Pokaż więcej
Źródło:
Cancer Medicine. Jun2023, Vol. 12 Issue 12, p13182-13192. 11p.
Czasopismo naukowe
Tytuł:
Cytological Diagnosis of Classic Myeloproliferative Neoplasms at the Age of Molecular Biology.
Autorzy:
Combaluzier, Sophie (AUTHOR)
Quessada, Julie (AUTHOR)
Abbou, Norman (AUTHOR)
Arcani, Robin (AUTHOR)
Tichadou, Antoine (AUTHOR)
Gabert, Jean (AUTHOR)
Costello, Régis (AUTHOR)
Loosveld, Marie (AUTHOR)
Venton, Geoffroy (AUTHOR)
Berda-Haddad, Yaël (AUTHOR)
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Źródło:
Cells (2073-4409). Mar2023, Vol. 12 Issue 6, p946. 23p.
Czasopismo naukowe
Tytuł:
Lenalidomide treatment for patients with myelodysplastic syndrome and low blast count acute myeloid leukemia after azacitidine failure.
Autorzy:
Prebet T
Charbonnier A
Gelsi-Boyer V
Mozziconacci MJ
Blaise D
Vey N
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2013 Jul; Vol. 54 (7), pp. 1538-40. Date of Electronic Publication: 2012 Nov 29.
Typ publikacji:
Letter
MeSH Terms:
Leukemia, Myeloid, Acute/*drug therapy
Leukemia, Myeloid, Acute/*pathology
Myelodysplastic Syndromes/*drug therapy
Thalidomide/*analogs & derivatives
Azacitidine/administration & dosage ; Azacitidine/therapeutic use ; Humans ; Lenalidomide ; Leukemia, Myeloid, Acute/mortality ; Myelodysplastic Syndromes/mortality ; Thalidomide/administration & dosage ; Thalidomide/therapeutic use ; Treatment Failure ; Treatment Outcome
Opinia redakcyjna
Tytuł:
Impact of Molecular Biology in Diagnosis, Prognosis, and Therapeutic Management of BCR::ABL1 -Negative Myeloproliferative Neoplasm.
Autorzy:
Abbou, Norman (AUTHOR)
Piazzola, Pauline (AUTHOR)
Gabert, Jean (AUTHOR)
Ernest, Vincent (AUTHOR)
Arcani, Robin (AUTHOR)
Couderc, Anne-Laure (AUTHOR)
Tichadou, Antoine (AUTHOR)
Roche, Pauline (AUTHOR)
Farnault, Laure (AUTHOR)
Colle, Julien (AUTHOR)
Ouafik, L'houcine (AUTHOR)
Morange, Pierre (AUTHOR)
Costello, Régis (AUTHOR)
Venton, Geoffroy (AUTHOR)
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Źródło:
Cells (2073-4409). Jan2023, Vol. 12 Issue 1, p105. 12p.
Czasopismo naukowe
Tytuł:
A Novel Chalcone Derivative Regulates the Expression and Phosphorylation of ERK1/2 by Inhibiting Fli-1 Promoter Activity for Preventing the Malignant Progression of Erythroleukemia.
Autorzy:
Mo, Min (AUTHOR)
Ma, Youfen (AUTHOR)
Yu, Jia (AUTHOR)
Ahmad, Mashaal (AUTHOR)
Wan, Xinwei (AUTHOR)
Yu, Zijiang (AUTHOR)
Xu, Bixue (AUTHOR)
Luo, Heng (AUTHOR)
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Źródło:
Catalysts (2073-4344). Jan2023, Vol. 13 Issue 1, p84. 19p.
Czasopismo naukowe
Tytuł:
Tumor mutation burden involving epigenetic regulatory genes and the RhoA GTPase predicts overall survival in nodal mature T-cell lymphomas.
Autorzy:
de Pádua Covas Lage, Luís Alberto (AUTHOR)
Culler, Hebert Fabrício (AUTHOR)
Barreto, Guilherme Carneiro (AUTHOR)
Reichert, Cadiele Oliana (AUTHOR)
Levy, Débora (AUTHOR)
de Oliveira Costa, Renata (AUTHOR)
Rocha, Vanderson (AUTHOR)
Pereira, Juliana (AUTHOR)
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Źródło:
Clinical Epigenetics. 12/19/2022, Vol. 14 Issue 1, p1-8. 8p.
Czasopismo naukowe
Tytuł:
Increased copy number of imprinted genes in the chromosomal region 20q11-q13.32 is associated with resistance to antitumor agents in cancer cell lines.
Autorzy:
Krushkal, Julia (AUTHOR)
Vural, Suleyman (AUTHOR)
Jensen, Travis L. (AUTHOR)
Wright, George (AUTHOR)
Zhao, Yingdong (AUTHOR)
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Źródło:
Clinical Epigenetics. 12/2/2022, Vol. 14 Issue 1, p1-26. 26p.
Czasopismo naukowe
Tytuł:
The prognostic value of the interaction between ASXL1 and TET2 gene mutations in patients with chronic myelomonocytic leukemia: a meta-analysis.
Autorzy:
Zhao, Wenxia (AUTHOR)
Zhang, Conghui (AUTHOR)
Li, Yiming (AUTHOR)
Li, Yang (AUTHOR)
Liu, Yang (AUTHOR)
Sun, Xiaoyu (AUTHOR)
Liu, Mingyan (AUTHOR)
Shao, Rongguang (AUTHOR)
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Źródło:
Hematology. Dec2022, Vol. 27 Issue 1, p367-378. 12p.
Czasopismo naukowe
Tytuł:
The Revelation of Continuously Organized, Co-Overexpressed Protein-Coding Genes with Roles in Cellular Communications in Breast Cancer.
Autorzy:
Paul, Aswathy Mary (AUTHOR)
Amjesh, Revikumar (AUTHOR)
George, Bijesh (AUTHOR)
Sankaran, Deivendran (AUTHOR)
Sandiford, Oleta A. (AUTHOR)
Rameshwar, Pranela (AUTHOR)
Pillai, Madhavan Radhakrishna (AUTHOR)
Kumar, Rakesh (AUTHOR)
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Źródło:
Cells (2073-4409). Dec2022, Vol. 11 Issue 23, p3806. 25p.
Czasopismo naukowe
Tytuł:
Myeloid malignancies: mutations, models and management.
Autorzy:
Murati A; Centre de Recherche en Cancérologie de Marseille, Laboratoire d'Oncologie Moléculaire; UMR1068 Inserm, Institut Paoli-Calmettes, 27 Bd, Leï Roure, BP 30059, Marseille, 13273, France.
Brecqueville M
Devillier R
Mozziconacci MJ
Gelsi-Boyer V
Birnbaum D
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Źródło:
BMC cancer [BMC Cancer] 2012 Jul 23; Vol. 12, pp. 304. Date of Electronic Publication: 2012 Jul 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Mutation*
Leukemia, Myeloid/*genetics
Myelodysplastic Syndromes/*genetics
Myeloproliferative Disorders/*genetics
Cell Transformation, Neoplastic/genetics ; Humans ; Leukemia, Myeloid/metabolism ; Leukemia, Myeloid/therapy ; Models, Biological ; Myelodysplastic Syndromes/metabolism ; Myelodysplastic Syndromes/therapy ; Myeloproliferative Disorders/metabolism ; Myeloproliferative Disorders/therapy
Czasopismo naukowe
Tytuł:
Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.
Autorzy:
Gelsi-Boyer V; Centre de Recherche en Cancérologie de Marseille, Laboratoire d'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, Marseille, France. />Brecqueville M
Devillier R
Murati A
Mozziconacci MJ
Birnbaum D
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2012 Mar 21; Vol. 5, pp. 12. Date of Electronic Publication: 2012 Mar 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Mutation*/physiology
Bone Marrow Diseases/*classification
Bone Marrow Diseases/*diagnosis
Bone Marrow Diseases/*genetics
Repressor Proteins/*genetics
DNA Mutational Analysis ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myelomonocytic, Chronic/diagnosis ; Leukemia, Myelomonocytic, Chronic/genetics ; Models, Biological ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/genetics ; Myeloproliferative Disorders/diagnosis ; Myeloproliferative Disorders/genetics ; Prognosis
Czasopismo naukowe
Tytuł:
Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias.
Autorzy:
Rocquain J; Laboratoire d'Oncologie Moléculaire, UMR891 Inserm, Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille, Marseille, France.
Carbuccia N
Trouplin V
Raynaud S
Murati A
Nezri M
Tadrist Z
Olschwang S
Vey N
Birnbaum D
Gelsi-Boyer V
Mozziconacci MJ
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Źródło:
BMC cancer [BMC Cancer] 2010 Aug 02; Vol. 10, pp. 401. Date of Electronic Publication: 2010 Aug 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Leukemia, Myeloid, Acute/*genetics
Mutation/*genetics
Myelodysplastic Syndromes/*genetics
Neoplasm Proteins/*genetics
Aged ; Aged, 80 and over ; Core Binding Factor Alpha 2 Subunit/genetics ; DNA, Neoplasm/genetics ; DNA-Binding Proteins/genetics ; Dioxygenases ; Female ; Genes, ras/physiology ; Humans ; Isocitrate Dehydrogenase/genetics ; Janus Kinase 2/genetics ; Leukemia, Myeloid, Acute/pathology ; Male ; Middle Aged ; Myelodysplastic Syndromes/pathology ; Nuclear Proteins/genetics ; Nucleophosmin ; Polymerase Chain Reaction ; Prognosis ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins c-cbl/genetics ; Proto-Oncogene Proteins p21(ras) ; Repressor Proteins/genetics ; WT1 Proteins/genetics ; fms-Like Tyrosine Kinase 3/genetics ; ras Proteins/genetics
Czasopismo naukowe
Tytuł:
Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1 genes.
Autorzy:
Gelsi-Boyer V; Centre de Recherche en Cancérologie de Marseille, Laboratoire d'Oncologie Moléculaire, UMR891 Inserm, Institut Paoli-Calmettes, Marseille, France. />Trouplin V
Adélaïde J
Aceto N
Remy V
Pinson S
Houdayer C
Arnoulet C
Sainty D
Bentires-Alj M
Olschwang S
Vey N
Mozziconacci MJ
Birnbaum D
Chaffanet M
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Źródło:
BMC cancer [BMC Cancer] 2008 Oct 16; Vol. 8, pp. 299. Date of Electronic Publication: 2008 Oct 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Profiling*
Core Binding Factor Alpha 2 Subunit/*genetics
Genes, ras/*genetics
Leukemia, Myelomonocytic, Chronic/*genetics
Chromosomes, Human, Pair 21 ; Comparative Genomic Hybridization ; Humans ; Leukemia, Myelomonocytic, Chronic/pathology ; Mutation ; Oncogene Proteins, Fusion/genetics ; Sequence Analysis, DNA ; Signal Transduction/genetics ; Ubiquitin Thiolesterase/genetics
Czasopismo naukowe
Tytuł:
Targeted NGS on sequential bone marrow biopsies aids in the evaluation of cytopenias and monocytosis and documents clonal evolution—a proof of principle study
Autorzy:
Nann, Dominik
Rau, Achim
Mahmutovic, Lejla
Steinhilber, Julia
Meca, Vanessa
Federmann, BirgitAff1, Aff2, Aff3, Aff4
Vogel, Wichard
Bonzheim, Irina
Quintanilla-Martinez, LeticiaAff1, Aff4
Fend, FalkoAff1, IDs00428023036271_cor10
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Źródło:
Virchows Archiv: European Journal of Pathology. 483(6):835-845
Czasopismo naukowe
Tytuł:
PCR‐Fluo‐ASXL1‐FA: A fast, sensitive and inexpensive complementary method to detect ASXL1 mutations in haematological malignancies.
Autorzy:
Friedrich, Chloé
Zalmaï, Loria
Gay, Juliette
Coude, Marie Magdeleine
Bravetti, Clotilde
Vazquez, Romain
Temple, Marie
Duroyon, Eugénie
Darnige, Luc
Decroocq, Justine
Alary, Anne Sophie
Kosmider, Olivier
Pokaż więcej
Źródło:
International Journal of Laboratory Hematology. Oct2022, Vol. 44 Issue 5, p928-933. 6p.
Czasopismo naukowe
Tytuł:
The characteristics and clinical prognosis analysis of ASXL1 mutations in Chinese adult patients with primary cytogenetically normal acute myeloid leukemia by next-generation sequencing.
Autorzy:
Xu, Jing (AUTHOR)
Hao, Zhuanghui (AUTHOR)
Chen, Xian (AUTHOR)
Hong, Minglin (AUTHOR)
Muyey, Daniel muteb (AUTHOR)
Chen, Xiuhua (AUTHOR)
Wang, Hongwei (AUTHOR)
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Źródło:
Leukemia & Lymphoma. Oct2022, Vol. 63 Issue 10, p2321-2329. 9p.
Czasopismo naukowe
Tytuł:
The ABNL-MARRO 001 study: a phase 1–2 study of randomly allocated active myeloid target compound combinations in MDS/MPN overlap syndromes.
Autorzy:
Moyo, Tamara K. (AUTHOR)
Mendler, Jason H. (AUTHOR)
Itzykson, Raphael (AUTHOR)
Kishtagari, Ashwin (AUTHOR)
Solary, Eric (AUTHOR)
Seegmiller, Adam C. (AUTHOR)
Gerds, Aaron T. (AUTHOR)
Ayers, Gregory D. (AUTHOR)
Dezern, Amy E. (AUTHOR)
Nazha, Aziz (AUTHOR)
Valent, Peter (AUTHOR)
van de Loosdrecht, Arjan A. (AUTHOR)
Onida, Francesco (AUTHOR)
Pleyer, Lisa (AUTHOR)
Cirici, Blanca Xicoy (AUTHOR)
Tibes, Raoul (AUTHOR)
Geissler, Klaus (AUTHOR)
Komrokji, Rami S. (AUTHOR)
Zhang, Jing (AUTHOR)
Germing, Ulrich (AUTHOR)
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Źródło:
BMC Cancer. 9/25/2022, Vol. 22 Issue 1, p1-15. 15p.
Czasopismo naukowe
Tytuł:
Zrsr2 Is Essential for the Embryonic Development and Splicing of Minor Introns in RNA and Protein Processing Genes in Zebrafish.
Autorzy:
Weinstein, Rachel (AUTHOR)
Bishop, Kevin (AUTHOR)
Broadbridge, Elizabeth (AUTHOR)
Yu, Kai (AUTHOR)
Carrington, Blake (AUTHOR)
Elkahloun, Abdel (AUTHOR)
Zhen, Tao (AUTHOR)
Pei, Wuhong (AUTHOR)
Burgess, Shawn M. (AUTHOR)
Liu, Paul (AUTHOR)
Bresciani, Erica (AUTHOR)
Sood, Raman (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Sep2022, Vol. 23 Issue 18, pN.PAG-N.PAG. 15p.
Czasopismo naukowe
Tytuł:
Real-World Data on Chronic Myelomonocytic Leukemia: Clinical and Molecular Characteristics, Treatment, Emerging Drugs, and Patient Outcomes.
Autorzy:
Castaño-Díez, Sandra (AUTHOR)
López-Guerra, Mónica (AUTHOR)
Bosch-Castañeda, Cristina (AUTHOR)
Bataller, Alex (AUTHOR)
Charry, Paola (AUTHOR)
Esteban, Daniel (AUTHOR)
Guijarro, Francesca (AUTHOR)
Jiménez-Vicente, Carlos (AUTHOR)
Castillo-Girón, Carlos (AUTHOR)
Cortes, Albert (AUTHOR)
Martínez-Roca, Alexandra (AUTHOR)
Triguero, Ana (AUTHOR)
Álamo, José Ramón (AUTHOR)
Beà, Silvia (AUTHOR)
Costa, Dolors (AUTHOR)
Colomer, Dolors (AUTHOR)
Rozman, María (AUTHOR)
Esteve, Jordi (AUTHOR)
Díaz-Beyá, Marina (AUTHOR)
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Źródło:
Cancers. Sep2022, Vol. 14 Issue 17, p4107. 21p.
Czasopismo naukowe
Tytuł:
High-Throughput CRISPR Screening in Hematological Neoplasms.
Autorzy:
Ancos-Pintado, Raquel (AUTHOR)
Bragado-García, Irene (AUTHOR)
Morales, María Luz (AUTHOR)
García-Vicente, Roberto (AUTHOR)
Arroyo-Barea, Andrés (AUTHOR)
Rodríguez-García, Alba (AUTHOR)
Martínez-López, Joaquín (AUTHOR)
Linares, María (AUTHOR)
Hernández-Sánchez, María (AUTHOR)
Pokaż więcej
Źródło:
Cancers. Aug2022, Vol. 14 Issue 15, p3612-3612. 34p.
Czasopismo naukowe
Tytuł:
Genomic landscape of myelodysplastic/myeloproliferative neoplasm can predict response to hypomethylating agent therapy.
Autorzy:
Karantanos, Theodoros (AUTHOR)
Tsai, Hua-Ling (AUTHOR)
Gondek, Lukasz P. (AUTHOR)
DeZern, Amy E. (AUTHOR)
Ghiaur, Gabriel (AUTHOR)
Dalton, W. Brian (AUTHOR)
Gojo, Ivana (AUTHOR)
Prince, Gabrielle T. (AUTHOR)
Webster, Jonathan (AUTHOR)
Ambinder, Alexander (AUTHOR)
Smith, B. Douglas (AUTHOR)
Levis, Mark J. (AUTHOR)
Varadhan, Ravi (AUTHOR)
Jones, Richard J. (AUTHOR)
Jain, Tania (AUTHOR)
Pokaż więcej
Źródło:
Leukemia & Lymphoma. Aug2022, Vol. 63 Issue 8, p1942-1948. 7p.
Czasopismo naukowe
Tytuł:
Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers.
Autorzy:
Letessier A; Centre de Recherche en Cancérologie de Marseille, Département d'Oncologie Moléculaire, UMR599 Inserm/Institut Paoli-Calmettes, Marseille, France. <>
Sircoulomb F
Ginestier C
Cervera N
Monville F
Gelsi-Boyer V
Esterni B
Geneix J
Finetti P
Zemmour C
Viens P
Charafe-Jauffret E
Jacquemier J
Birnbaum D
Chaffanet M
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2006 Oct 13; Vol. 6, pp. 245. Date of Electronic Publication: 2006 Oct 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chromosomes, Human, Pair 11*
Chromosomes, Human, Pair 12*
Chromosomes, Human, Pair 17*
Chromosomes, Human, Pair 20*
Chromosomes, Human, Pair 8*
Gene Amplification*
Breast Neoplasms/*genetics
Carcinoma/*genetics
Adult ; Aged ; Aged, 80 and over ; Biomarkers ; Female ; Gene Frequency ; Humans ; Middle Aged ; Models, Biological ; Neoplasm Metastasis/diagnosis ; Prognosis ; Statistics as Topic
Czasopismo naukowe
Tytuł:
Integrated genomic sequencing in myeloid blast crisis chronic myeloid leukemia (MBC-CML), identified potentially important findings in the context of leukemogenesis model.
Autorzy:
Kazemi-Sefat, Golnaz Ensieh (AUTHOR)
Keramatipour, Mohammad (AUTHOR)
Vaezi, Mohammad (AUTHOR)
Razavi, Seyed Mohsen (AUTHOR)
Kavousi, Kaveh (AUTHOR)
Talebi, Amin (AUTHOR)
Rostami, Shahrbanoo (AUTHOR)
Yaghmaei, Marjan (AUTHOR)
Chahardouli, Bahram (AUTHOR)
Talebi, Saeed (AUTHOR)
Mousavizadeh‬, Kazem (AUTHOR)
Pokaż więcej
Źródło:
Scientific Reports. 7/27/2022, Vol. 12 Issue 1, p1-13. 13p.
Czasopismo naukowe
Tytuł:
Mutations in the miR-142 gene are not common in myeloproliferative neoplasms.
Autorzy:
Galka-Marciniak, Paulina (AUTHOR)
Kanduła, Zuzanna (AUTHOR)
Tire, Adrian (AUTHOR)
Wegorek, Wladyslaw (AUTHOR)
Gwozdz-Bak, Kinga (AUTHOR)
Handschuh, Luiza (AUTHOR)
Giefing, Maciej (AUTHOR)
Lewandowski, Krzysztof (AUTHOR)
Kozlowski, Piotr (AUTHOR)
Pokaż więcej
Źródło:
Scientific Reports. 6/28/2022, Vol. 12 Issue 1, p1-5. 5p.
Czasopismo naukowe

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