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Tytuł :
Profiling transcriptomic changes and signaling pathways in atopic dermatitis by integrative analyses on multiple databases.
Autorzy :
Xu Y; Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000, Zhejiang, China.
Chen S; Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000, Zhejiang, China.
Chen J; Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000, Zhejiang, China. .
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Źródło :
Molecular genetics and genomics : MGG [Mol Genet Genomics] 2021 Mar; Vol. 296 (2), pp. 341-353. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Computational Biology/*methods
Dermatitis, Atopic/*genetics
Dinitrofluorobenzene/*analogs & derivatives
Gene Expression Profiling/*methods
Animals ; Databases, Genetic ; Dermatitis, Atopic/chemically induced ; Dinitrofluorobenzene/adverse effects ; Disease Models, Animal ; Gene Expression Regulation ; Humans ; Male ; Mice ; Protein Interaction Maps ; Signal Transduction
Czasopismo naukowe
Tytuł :
Transcriptome analysis identifies the differentially expressed genes related to the stemness of limbal stem cells in mice.
Autorzy :
Guo ZH; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China; Stem Cell Laboratory, The Second Affiliated Hospital of Fujian Medical University, China.
Jia YYS; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China.
Zeng YM; The Second Affiliated Hospital of Fujian Medical University, China.
Li ZF; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China.
Lin JS; School of Medicine, Huaqiao University, Quanzhou, Fujian 362021, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Apr 05; Vol. 775, pp. 145447. Date of Electronic Publication: 2021 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Epithelium, Corneal/*chemistry
Gene Expression Profiling/*veterinary
Animals ; Cells, Cultured ; Conjunctiva/chemistry ; Gene Expression Regulation ; High-Throughput Nucleotide Sequencing ; Mice ; Protein Interaction Maps ; Sequence Analysis, RNA ; Stem Cells/chemistry
Czasopismo naukowe
Tytuł :
Genotype and transcriptome effects on somatic embryogenesis in Cryptomeria japonica.
Autorzy :
Izuno A; Department of Forest Molecular Genetics and Biotechnology, Forestry and Forest Products Research Institute, Tsukuba, Ibaraki, Japan.
Maruyama TE; Department of Forest Molecular Genetics and Biotechnology, Forestry and Forest Products Research Institute, Tsukuba, Ibaraki, Japan.
Ueno S; Department of Forest Molecular Genetics and Biotechnology, Forestry and Forest Products Research Institute, Tsukuba, Ibaraki, Japan.
Ujino-Ihara T; Department of Forest Molecular Genetics and Biotechnology, Forestry and Forest Products Research Institute, Tsukuba, Ibaraki, Japan.
Moriguchi Y; Graduate School of Science and Technology, Niigata University, Niigata, Japan.
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Źródło :
PloS one [PLoS One] 2020 Dec 29; Vol. 15 (12), pp. e0244634. Date of Electronic Publication: 2020 Dec 29 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Cryptomeria/*growth & development
Gene Expression Profiling/*methods
Plant Somatic Embryogenesis Techniques/*methods
Cryptomeria/genetics ; Gene Expression Regulation, Developmental ; Gene Expression Regulation, Plant ; Genetic Variation ; Genotype ; Japan ; Plant Proteins ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
Identification of immune-related genes as prognostic factors in bladder cancer.
Autorzy :
Zhu J; Department of Oncology, Changzhou Traditional Chinese Medical Hospital, Changzhou, 213003, Jiangsu, People's Republic of China.
Wang H; Department of Oncology, Jining Tumour Hospital, Jining, People's Republic of China.
Ma T; Department of Oncology, Changzhou Traditional Chinese Medical Hospital, Changzhou, 213003, Jiangsu, People's Republic of China.
He Y; Department of Radio-Oncology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215001, Jiangsu, People's Republic of China.
Shen M; Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, People's Republic of China.
Song W; Department of Gastrointestinal Surgery II, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China.
Wang JJ; Department of Oncology, Taizhou Hospital of Traditional Chinese Medicine, Taizhou, People's Republic of China.
Shi JP; Department of Radio-Oncology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215001, Jiangsu, People's Republic of China.
Wu MY; Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, People's Republic of China.
Liu C; Department of Urology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215001, Jiangsu, People's Republic of China.
Wang WJ; Department of Radio-Oncology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215001, Jiangsu, People's Republic of China. .
Huang YQ; Department of General Practice, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, People's Republic of China.
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 12; Vol. 10 (1), pp. 19695. Date of Electronic Publication: 2020 Nov 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Biomarkers, Tumor/*genetics
Gene Expression Profiling/*methods
Urinary Bladder Neoplasms/*immunology
Case-Control Studies ; Female ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Humans ; Immunity ; Male ; Nomograms ; Prognosis ; ROC Curve ; Regression Analysis ; Sequence Analysis, RNA ; Software ; Survival Analysis ; Transcription Factors/genetics ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/mortality
Czasopismo naukowe
Tytuł :
Proteomic analysis of hypopharyngeal and laryngeal squamous cell carcinoma sheds light on differences in survival.
Autorzy :
Liu J; Department of Otolaryngology-Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410010, China.
Zhu W; Fuzhou Medical College of Nanchang University, Fuzhou, 344000, China.
Li Z; Department of Otolaryngology-Head and Neck Surgery, The Xiangya Hospital, Central South University, Changsha, 410008, China.
Cai G; Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Quanzhou, Fujian Medical University, Quanzhou, 362000, China.
Wang J; Department of Otolaryngology-Head and Neck Surgery, The Xiangya Hospital, Central South University, Changsha, 410008, China.
Tang Q; Department of Otolaryngology-Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410010, China.
Maroun CA; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, 21287, USA.
Zhu G; Department of Otolaryngology-Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410010, China. .; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, 21287, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 10; Vol. 10 (1), pp. 19459. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Carcinoma, Squamous Cell/*genetics
Gene Expression Profiling/*methods
Hypopharyngeal Neoplasms/*genetics
Laryngeal Neoplasms/*genetics
Proteomics/*methods
Aged ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Chromatography, Liquid/methods ; Female ; Gene Ontology ; Gene Regulatory Networks ; Humans ; Hypopharyngeal Neoplasms/metabolism ; Hypopharyngeal Neoplasms/pathology ; Kaplan-Meier Estimate ; Laryngeal Neoplasms/metabolism ; Laryngeal Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Staging ; Tandem Mass Spectrometry/methods
Czasopismo naukowe
Tytuł :
Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short- and long-term models.
Autorzy :
Liu HL; Department of Emergency Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Yeh IJ; Department of Emergency Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Phan NN; NTT Institute of Hi-Technology, Nguyen Tat Thanh University, Ho Chi Minh City, Viet Nam.
Wu YH; Department of Emergency Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Yen MC; Department of Emergency Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Hung JH; Department of Biotechnology, Chia Nan University of Pharmacy and Science, Tainan 71710, Taiwan.
Chiao CC; School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung 82445, Taiwan.
Chen CF; School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung 82445, Taiwan.
Sun Z; Kaiser Permanente, Northern California Regional Laboratories, The Permanente Medical Group, 1725 Eastshore Hwy, Berkeley, CA 94710, USA.
Jiang JZ; Emergency Department, Huashan Hospital North, Fudan University, Shanghai 201508, People's Republic of China.
Hsu HP; Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN 37232, USA. Electronic address: .
Wang CY; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan. Electronic address: .
Lai MD; Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan 70101, Taiwan; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan. Electronic address: .
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Źródło :
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2020 Nov; Vol. 85, pp. 104438. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
COVID-19/*genetics
Gene Expression Profiling/*methods
Lung/*virology
Animals ; COVID-19/metabolism ; COVID-19/virology ; Computational Biology/methods ; Disease Models, Animal ; Disease Progression ; Ferrets ; Gene Expression Regulation ; Gene Ontology ; Reactive Oxygen Species/metabolism ; SARS-CoV-2/pathogenicity
Czasopismo naukowe
Tytuł :
Systematic analysis of molecular mechanisms of heart failure through the pathway and network-based approach.
Autorzy :
Zhang K; Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital & Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, China.
Qin X; Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital & Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, China.
Wen P; Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital & Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, China.
Wu Y; Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital & Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, China. Electronic address: .
Zhuang J; Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital & Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 15; Vol. 265, pp. 118830. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Gene Expression Profiling/*methods
Heart Failure/*genetics
Ventricular Remodeling/*genetics
Gene Ontology ; Heart Failure/physiopathology ; Humans ; RNA, Untranslated/genetics ; Transcription Factors/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Full-Length Transcriptome Analysis of Four Different Tissues of Cephalotaxus oliveri .
Autorzy :
He Z; School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.
Su Y; School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.; Research Institute of Sun Yat-sen University in Shenzhen, Shenzhen 518057, China.
Wang T; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 14; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 14.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Plant*
Cephalotaxus/*genetics
Gene Expression Profiling/*methods
Transcriptome/*genetics
Cytochrome P-450 Enzyme System/classification ; Cytochrome P-450 Enzyme System/genetics ; Gene Ontology ; Molecular Sequence Annotation ; Organ Specificity/genetics ; Phylogeny ; Plant Leaves/genetics ; Plant Proteins/classification ; Plant Proteins/genetics ; Plant Roots/genetics ; Plant Stems/genetics ; Seeds/genetics ; Sequence Analysis, RNA/methods
Czasopismo naukowe
Tytuł :
Genome-Wide Characterization, Evolution, and Expression Profile Analysis of GATA Transcription Factors in Brachypodium distachyon .
Autorzy :
Peng W; Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha 410128, China.; College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
Li W; Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha 410128, China.; College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
Song N; Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha 410128, China.; College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
Tang Z; Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha 410128, China.; College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
Liu J; Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha 410128, China.; College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
Wang Y; Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha 410128, China.; College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
Pan S; Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha 410128, China.; College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
Dai L; Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha 410128, China.; College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
Wang B; Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha 410128, China.; College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 18; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article
MeSH Terms :
Evolution, Molecular*
Gene Expression Profiling*
Gene Expression Regulation, Plant*/drug effects
Genome, Plant*
Brachypodium/*genetics
GATA Transcription Factors/*genetics
Amino Acid Motifs ; Ascomycota/drug effects ; Ascomycota/physiology ; Brachypodium/drug effects ; Chromosomes, Plant/genetics ; Conserved Sequence/genetics ; GATA Transcription Factors/chemistry ; GATA Transcription Factors/metabolism ; Gene Duplication ; Gene Regulatory Networks/drug effects ; Genes, Plant ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Phylogeny ; Plant Growth Regulators/pharmacology ; Synteny/genetics
SCR Organism :
Pyricularia oryzae
Czasopismo naukowe
Tytuł :
Physiological and transcriptomic analyses of yellow horn (Xanthoceras sorbifolia) provide important insights into salt and saline-alkali stress tolerance.
Autorzy :
Wang J; College of Forestry, Shanxi Agricultural University, Taigu, Shanxi, China.; Shanxi Key Laboratory of Functional Oil Tree Cultivation and Research, Taigu, Shanxi, China.
Zhang Y; College of Forestry, Shanxi Agricultural University, Taigu, Shanxi, China.; Shanxi Key Laboratory of Functional Oil Tree Cultivation and Research, Taigu, Shanxi, China.
Yan X; College of Forestry, Shanxi Agricultural University, Taigu, Shanxi, China.; Shanxi Key Laboratory of Functional Oil Tree Cultivation and Research, Taigu, Shanxi, China.
Guo J; College of Forestry, Shanxi Agricultural University, Taigu, Shanxi, China.; Shanxi Key Laboratory of Functional Oil Tree Cultivation and Research, Taigu, Shanxi, China.
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Źródło :
PloS one [PLoS One] 2020 Dec 22; Vol. 15 (12), pp. e0244365. Date of Electronic Publication: 2020 Dec 22 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Electrolytes/*metabolism
Gene Expression Profiling/*methods
Malondialdehyde/*metabolism
Sapindaceae/*growth & development
China ; Chlorophyll/metabolism ; Gene Expression Regulation, Plant ; High-Throughput Nucleotide Sequencing ; Plant Proteins/genetics ; Salt Tolerance ; Sapindaceae/genetics ; Sapindaceae/metabolism ; Sequence Analysis, RNA ; Stress, Physiological
Czasopismo naukowe
Tytuł :
Differential Co-Expression Analyses Allow the Identification of Critical Signalling Pathways Altered during Tumour Transformation and Progression.
Autorzy :
Savino A; Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, Via Nizza 52, 10126 Turin, Italy.
Provero P; Department of Neurosciences 'Rita Levi Montalcini', University of Turin, Corso Massimo D'Ázeglio 52, 10126 Turin, Italy.; Center for Omics Sciences, Ospedale San Raffaele IRCCS, Via Olgettina 60, 20132 Milan, Italy.
Poli V; Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Turin, Via Nizza 52, 10126 Turin, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 12; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gene Regulatory Networks*
Computational Biology/*methods
Gene Expression Regulation, Neoplastic/*genetics
Neoplasms/*metabolism
Signal Transduction/*genetics
Algorithms ; Disease Progression ; Gene Expression Profiling ; Humans ; Neoplasms/genetics ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s.
Autorzy :
Tunbak H; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, E1 2AT, UK.
Enriquez-Gasca R; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, E1 2AT, UK.
Tie CHC; Infection and Immunity, University College London, London, WC1E 6BT, UK.
Gould PA; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, E1 2AT, UK.
Mlcochova P; Department of Medicine, University of Cambridge, CB2 0AF, Cambridge, UK.
Gupta RK; Department of Medicine, University of Cambridge, CB2 0AF, Cambridge, UK.
Fernandes L; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, E1 2AT, UK.
Holt J; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, E1 2AT, UK.
van der Veen AG; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; Leiden University Medical Centre, Department of Immunohematology and Blood Transfusion, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
Giampazolias E; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Burns KH; Department of Pathology, John Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Maillard PV; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, E1 2AT, UK.
Rowe HM; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, E1 2AT, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Nov 03; Vol. 11 (1), pp. 5387. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Epigenesis, Genetic/*physiology
Gene Silencing/*physiology
Interferon Type I/*metabolism
Long Interspersed Nucleotide Elements/*physiology
DEAD Box Protein 58/genetics ; DEAD Box Protein 58/metabolism ; DNA Damage ; Down-Regulation ; Gene Knockout Techniques ; HEK293 Cells ; HeLa Cells ; Humans ; Inflammation ; Interferon-Induced Helicase, IFIH1/metabolism ; Long Interspersed Nucleotide Elements/genetics ; Phosphoproteins/metabolism ; RNA, Double-Stranded ; Sequence Analysis, RNA ; Signal Transduction
Czasopismo naukowe
Tytuł :
Comparative physiological and transcriptomic analysis of pear leaves under distinct training systems.
Autorzy :
Liu Z; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China. .
An L; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.; College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Lin S; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.; College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Wu T; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.
Li X; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.
Tu J; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.
Yang F; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.
Zhu H; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.
Yang L; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.
Cheng Y; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China.
Qin Z; Research Institute of Fruit and Tea, Hubei Academy of Agricultural Sciences, Wuhan, 430064, China. .; College of Life Sciences, Wuhan University, Wuhan, 430072, China. .
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 03; Vol. 10 (1), pp. 18892. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Gene Expression Profiling/*methods
Pyrus/*physiology
Gene Expression Regulation, Plant ; High-Throughput Nucleotide Sequencing ; Photosynthesis ; Plant Leaves/genetics ; Plant Leaves/physiology ; Plant Proteins/genetics ; Pyrus/genetics ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
Therapy-related Myeloid Leukemia With the Translocation t(8;19)(p11;q13) Leading to a KAT6A-LEUTX Fusion Gene.
Autorzy :
Panagopoulos I; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; .
Andersen K; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Ramslien LF; Department of Cancer and Hematological Diseases, Telemark Hospital, Skien, Norway.
Ikonomou IM; Department of Pathology, Oslo University Hospital, Oslo, Norway.
Micci F; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Heim S; Section for Cancer Cytogenetics, Institute for Cancer Genetics and Informatics, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
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Źródło :
Anticancer research [Anticancer Res] 2021 Apr; Vol. 41 (4), pp. 1753-1760.
Typ publikacji :
Case Reports
MeSH Terms :
Chromosomes, Human, Pair 19*
Chromosomes, Human, Pair 8*
Gene Fusion*
Translocation, Genetic*
Biomarkers, Tumor/*genetics
Chemoradiotherapy/*adverse effects
Histone Acetyltransferases/*genetics
Homeodomain Proteins/*genetics
Leukemia, Myeloid, Acute/*etiology
Aged ; Female ; Gene Expression Regulation, Leukemic ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Treatment Outcome ; Uterine Cervical Neoplasms/therapy
Raport
Tytuł :
Weighted minimum feedback vertex sets and implementation in human cancer genes detection.
Autorzy :
Li R; Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto, 611-0011, Japan.
Lin CY; Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto, 611-0011, Japan.; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, 300, Hsinchu, Taiwan.; Center for Intelligent Drug Systems and Smart Bio-devices, National Yang Ming Chiao Tung University, 300, Hsinchu, Taiwan.
Guo WF; School of Electrical Engineering, Zhengzhou University, 450001, Zhengzhou, China.
Akutsu T; Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji, Kyoto, 611-0011, Japan. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Mar 22; Vol. 22 (1), pp. 143. Date of Electronic Publication: 2021 Mar 22.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Neoplasms*/genetics
Algorithms ; Computational Biology ; Feedback ; Gene Expression Profiling ; Humans ; Oncogenes ; Protein Interaction Maps
Czasopismo naukowe
Tytuł :
The origins and genetic interactions of KRAS mutations are allele- and tissue-specific.
Autorzy :
Cook JH; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Melloni GEM; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Gulhan DC; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Park PJ; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA. .
Haigis KM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. .; Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA. .; Broad Institute, Cambridge, MA, USA. .; Harvard Digestive Disease Center, Harvard Medical School, Boston, MA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 22; Vol. 12 (1), pp. 1808. Date of Electronic Publication: 2021 Mar 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Mutation*
Neoplasms/*genetics
Organ Specificity/*genetics
Proto-Oncogene Proteins p21(ras)/*genetics
Alleles ; Gene Expression Regulation, Neoplastic ; Gene Frequency ; Humans
Czasopismo naukowe
Tytuł :
The SR-protein Npl3 is an essential component of the meiotic splicing regulatory network in Saccharomyces cerevisiae.
Autorzy :
Sandhu R; Department of Viticulture and Enology, University of California Davis, Davis, CA, USA.
Sinha A; Department of Viticulture and Enology, University of California Davis, Davis, CA, USA.
Montpetit B; Department of Viticulture and Enology, University of California Davis, Davis, CA, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Mar 18; Vol. 49 (5), pp. 2552-2568.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Fungal*
RNA Splicing*
Meiosis/*genetics
Nuclear Proteins/*physiology
RNA-Binding Proteins/*physiology
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*physiology
Gene Deletion ; Gene Expression ; Introns ; Methylation ; Mitosis ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Recombination, Genetic ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł :
Downregulated ATP6V1B1 expression acidifies the intracellular environment of cancer cells leading to resistance to antibody-dependent cellular cytotoxicity.
Autorzy :
Nishie M; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Suzuki E; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. .; Department of Breast Surgery, Kyoto University Hospital, 54 Shogoin-kawaharacho, Sakyo-ku, Kyoto, 606-8507, Japan. .
Hattori M; Department of Immunosenescence, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kawaguch K; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kataoka TR; Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.
Hirata M; Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.
Pu F; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kotake T; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tsuda M; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yamaguchi A; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Sugie T; Department of Breast Surgery, Kansai Medical University, Osaka, Japan.
Toi M; Department of Breast Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Mar; Vol. 70 (3), pp. 817-830. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Antibody-Dependent Cell Cytotoxicity*
Gene Expression Regulation, Neoplastic*
Neoplasms/*genetics
Neoplasms/*immunology
Tumor Microenvironment/*genetics
Tumor Microenvironment/*immunology
Vacuolar Proton-Translocating ATPases/*genetics
Biomarkers ; Cell Line, Tumor ; Cell Proliferation ; Fluorescent Antibody Technique ; Gene Expression Profiling ; Gene Knockdown Techniques ; Humans ; Hydrogen-Ion Concentration ; Immunohistochemistry ; Intracellular Space/metabolism ; Neoadjuvant Therapy ; Neoplasms/drug therapy ; Neoplasms/pathology ; Treatment Outcome ; Vacuolar Proton-Translocating ATPases/metabolism
Czasopismo naukowe
Tytuł :
Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis.
Autorzy :
Song WM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.; Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.
Agrawal P; Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA.; Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center at NYU Langone Health, New York, NY, USA.
Von Itter R; Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA.; Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center at NYU Langone Health, New York, NY, USA.
Fontanals-Cirera B; Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA.; Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center at NYU Langone Health, New York, NY, USA.
Wang M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.; Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.
Zhou X; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.; Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.
Mahal LK; Department of Chemistry, University of Alberta, Edmonton, Canada.
Hernando E; Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA. .; Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center at NYU Langone Health, New York, NY, USA. .
Zhang B; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA. .; Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA. .; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA. .; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 22; Vol. 12 (1), pp. 1214. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Regulatory Networks*
Models, Biological*
Tumor Microenvironment*/genetics
Melanoma/*pathology
Skin Neoplasms/*pathology
Cell Line, Tumor ; DNA Repair ; DNA, Neoplasm/metabolism ; Gene Expression Regulation, Neoplastic ; Gene Silencing ; Humans ; Interferon-gamma/metabolism ; Melanoma/genetics ; Myosin Type I/metabolism ; Neoplasm Invasiveness ; Prognosis ; RNA Splicing/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reproducibility of Results ; Signal Transduction ; Skin Neoplasms/genetics ; Survival Analysis ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
New Gene Markers Expressed in Porcine Oviductal Epithelial Cells Cultured Primary In Vitro Are Involved in Ontological Groups Representing Physiological Processes of Porcine Oocytes.
Autorzy :
Kulus M; Department of Veterinary Surgery, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Kranc W; Department of Anatomy, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Wojtanowicz-Markiewicz K; Department of Veterinary Surgery, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Celichowski P; Department of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Światły-Błaszkiewicz A; Department of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, 60-780 Poznan, Poland.
Matuszewska E; Department of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, 60-780 Poznan, Poland.
Sujka-Kordowska P; Department of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.; Department of Anatomy and Histology, University of Zielona Gora, 65-046 Zielona Gora, Poland.
Konwerska A; Department of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Zdun M; Department of Basic and Preclinical Sciences, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Bryl R; Department of Anatomy, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Wieczorkiewicz M; Department of Basic and Preclinical Sciences, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Kulus J; Department of Diagnostics and Clinical Sciences, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Stelmach B; Division of Infertility and Reproductive Endocrinology, Department of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, 60-535 Poznan, Poland.
Stefańska K; Department of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Budna-Tukan J; Department of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Petitte JN; Prestage Department of Poultry Science, North Carolina State University, Raleigh, NC 27695, USA.
Mozdziak P; Prestage Department of Poultry Science, North Carolina State University, Raleigh, NC 27695, USA.
Ratajczak K; Department of Veterinary Surgery, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Matysiak J; Department of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, 60-780 Poznan, Poland.
Jaśkowski JM; Department of Diagnostics and Clinical Sciences, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Nowicki M; Department of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Kempisty B; Department of Veterinary Surgery, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.; Department of Anatomy, Poznan University of Medical Sciences, 60-781 Poznan, Poland.; Department of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland.; Prestage Department of Poultry Science, North Carolina State University, Raleigh, NC 27695, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 19; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Epithelial Cells/*metabolism
Oocytes/*metabolism
Oviducts/*cytology
Animals ; Cell Differentiation/genetics ; Cell Shape/genetics ; Cells, Cultured ; Down-Regulation/genetics ; Female ; Gene Ontology ; Gene Regulatory Networks ; Genetic Markers ; Signal Transduction/genetics ; Swine ; Transcriptome ; Up-Regulation/genetics
Czasopismo naukowe

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